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2. North American Practice-Based Recommendations for Transjugular Intrahepatic Portosystemic Shunts in Portal Hypertension.

Author

Boike, Justin, Thornburg, Bartley, Asrani, Sumeet, Fallon, Michael, Fortune, Brett, Izzy, Manhal, Verna, Elizabeth, Abraldes, Juan, Allegretti, Andrew, Bajaj, Jasmohan, Biggins, Scott, Darcy, Michael, Farr, Maryjane, Farsad, Khashayar, Garcia-Tsao, Guadalupe, Hall, Shelley, Jadlowiec, Caroline, Krowka, Michael, Laberge, Jeanne, Lee, Edward, Mulligan, David, Nadim, Mitra, Northup, Patrick, Salem, Riad, Shatzel, Joseph, Shaw, Cathryn, Simonetto, Douglas, Susman, Jonathan, Kolli, K, and VanWagner, Lisa

Subjects
Ascites, Cirrhosis, Complications, Consensus Statement, End-Stage Liver Disease, Guidance Document, TIPS Procedure, Variceal Bleeding, Ascites, Esophageal and Gastric Varices, Gastrointestinal Hemorrhage, Humans, Hypertension, Portal, Portasystemic Shunt, Transjugular Intrahepatic, Treatment Outcome
Abstract

Complications of portal hypertension, including ascites, gastrointestinal bleeding, hepatic hydrothorax, and hepatic encephalopathy, are associated with significant morbidity and mortality. Despite few high-quality randomized controlled trials to guide therapeutic decisions, transjugular intrahepatic portosystemic shunt (TIPS) creation has emerged as a crucial therapeutic option to treat complications of portal hypertension. In North America, the decision to perform TIPS involves gastroenterologists, hepatologists, and interventional radiologists, but TIPS creation is performed by interventional radiologists. This is in contrast to other parts of the world where TIPS creation is performed primarily by hepatologists. Thus, the successful use of TIPS in North America is dependent on a multidisciplinary approach and technical expertise, so as to optimize outcomes. Recently, new procedural techniques, TIPS stent technology, and indications for TIPS have emerged. As a result, practices and outcomes vary greatly across institutions and significant knowledge gaps exist. In this consensus statement, the Advancing Liver Therapeutic Approaches group critically reviews the application of TIPS in the management of portal hypertension. Advancing Liver Therapeutic Approaches convened a multidisciplinary group of North American experts from hepatology, interventional radiology, transplant surgery, nephrology, cardiology, pulmonology, and hematology to critically review existing literature and develop practice-based recommendations for the use of TIPS in patients with any cause of portal hypertension in terms of candidate selection, procedural best practices and, post-TIPS management; and to develop areas of consensus for TIPS indications and the prevention of complications. Finally, future research directions are identified related to TIPS for the management of portal hypertension.

Published
2022

3. Cirrhotic cardiomyopathy: Appraisal of the original and revised criteria in predicting posttransplant cardiac outcomes.

Author

Spann, Ashley, Ajayi, Teminioluwa, Montgomery, Garren, Shwetar, Mohammed, Oje, Adesola, Annis, Jeffrey, Slaughter, James, Alexopoulos, Sophoclis, Brittain, Evan, Izzy, Manhal, and Coe, Christopher

Subjects
Adult, Cardiomyopathies, Cardiovascular Diseases, Humans, Liver Cirrhosis, Liver Transplantation, Retrospective Studies, Risk Factors
Abstract

Cardiovascular disease (CVD) significantly contributes to morbidity and mortality after liver transplantation (LT). Cirrhotic cardiomyopathy (CCM) is a risk factor for CVD after transplant. CCM criteria were originally introduced in 2005 with a revision proposed in 2020 reflecting echocardiographic technology advancements. This study assesses the two criteria sets in predicting major adverse cardiac events (MACE) after transplant. This single-center retrospective study reviewed adult LT recipients between January 1, 2009, and December 31, 2018. Patients with insufficient pre-LT echocardiographic data, prior ischemic heart disease, portopulmonary hypertension, or longitudinal care elsewhere were excluded. The primary composite outcome was MACE (arrhythmia, heart failure, cardiac arrest, and/or cardiac death) after transplant. Of 1165 patients, 210 met the eligibility criteria. CCM was present in 162 patients (77%) per the original criteria and 64 patients (30%) per the revised criteria. There were 44 MACE and 31 deaths in the study period. Of the deaths, 38.7% occurred secondary to CVD. CCM defined by the original criteria was not associated with MACE after LT (p = 0.21), but the revised definition was significantly associated with MACE (hazard ratio [HR], 1.93; 95% confidence interval, 1.05-3.56; p = 0.04) on multivariable analysis. Echocardiographic variable analysis demonstrated low septal e as the most predictive variable for MACE after LT (HR, 3.45; p

Published
2022

4. Summary of a consensus conference on heart-liver transplantation

Author

Kobashigawa, Jon, VanWagner, Lisa B., Hall, Shelley, Ardehali, Abbas, Baran, David, Bhimaraj, Arvind, Bonham, Clark Andrew, Breda, Joao Roberto, Chen, Sharon, Czer, Lawrence, Alessandro, David D', Daugherty, Tami, De Marco, Teresa, Emamaullee, Juliet, Emerson, Dominic, Entwistle, John W., Esmailian, Fardad, Estep, Jerry, Gaber, Osama, Ganger, Daniel, Gebel, Howard, Ebel, Noelle Hanako, Harmath, Carla, Heimbach, Julie, Izzy, Manhal, Jackson, Annette, Jeevanandam, Val, Kahn, Jeffrey, Kaldas, Fady, Kamath, Patrick, Kilic, Ahmet, Kittleson, Michelle, Kuo, Alex, Kushwaha, Sudhir, Kwong, Allison, Lewis, Matthew, Loebe, Matthias, Lui, George, Madsen, Joren, McLean, Rhondalyn, Menachem, Jonathan, Mobley, Constance, Mufti, Arji, Patel, Jignesh, Pereira, Naveen, Pinney, Sean, Potter, Lisa, Sack, Jordan, Sahota, Amandeep, Schiano, Thomas D., Schlendorf, Kelly, Shingina, Alexandra, Takeda, Koji, Taner, Timucin, Te, Helen, Teuteberg, Jeffrey, Tompkins, Rose, Verna, Betsy, Wall, Anji, Jeevanandam, Valluvan, Lui, George K., Motayagheni, Negar, Patel, Nikhil, and Sani, Maryam

Published
2024
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7. Pancreatic adenocarcinoma in liver transplant recipients: a case series.

Author

Rauf, Muhammad, Ziogas, Ioannis, Sealock, Julia, Davis, Lea, Izzy, Manhal, Alexopoulos, Sophoclis, and Matsuoka, Lea

Subjects
Liver transplantation (LT), case series, immunosuppression, malignancy, pancreatic adenocarcinoma
Abstract

BACKGROUND: Malignancy is one of the known leading causes of death among long-term liver transplantation (LT) survivors. Pancreatic cancer has an incidence of 7.6/100,000 in North America and constitutes a diagnostic challenge post-LT. METHODS: This is a single-center, retrospective review of the electronic health records (EHRs) of LT recipients with pancreatic adenocarcinoma (1990-2019). The prevalence of pancreatic adenocarcinoma in our institutional non-LT population was assessed using an institutional de-identified database (Synthetic Derivative). RESULTS: Six out of 2,232 (0.27%) LT recipients were diagnosed with pancreatic adenocarcinoma. Median age at diagnosis was 66.0 years (IQR, 57.8-71.8 years). Median time from LT to pancreatic adenocarcinoma diagnosis was 8.9 years (IQR, 4.7-16.2 years), the median size on imaging was 3.2 cm (IQR, 3.1-4.7 cm), and all tumors were located on the head of the pancreas. Three patients underwent surgical resection (one with adjuvant chemotherapy), two underwent palliative care, and one palliative chemotherapy with gemcitabine and abraxane. Over a median follow-up of 220.5 days (IQR, 144.8-399.5 days), all six patients died due to disease progression (100%). Pancreatic adenocarcinoma was diagnosed in 5,033 out of 2,484,772 (0.20%) individuals in the Synthetic Derivative. CONCLUSIONS: Our findings identified an increased incidence of pancreatic adenocarcinoma following LT compared to the general population.

Published
2021

11. The novel SALT-M score predicts 1-year post-transplant mortality in patients with severe acute-on-chronic liver failure

Author

Al Attar, Atef, Kosari, Kambiz, Garcia, Richard, Salmastyan, Gevork, Cranford, William, Patel, Preet, Xue, Pei, Mishra, Soumya, Parks, Madison, Flocco, Gianina, Gao, Jing, Wu, Tiffany, Thanneeru, Priya, Reddy, Vikrant, Hurtado, Mariana, Mohamed, Islam, Vyhmeister, Ross, Lopez, Christine R., Campbell, Braidie, Winters, Adam C., Simpson, Mary Ann, Ying, Xiaohan, Hernaez, Ruben, Karvellas, Constantine J., Liu, Yan, Sacleux, Sophie-Caroline, Khemichian, Saro, Stein, Lance L., Shetty, Kirti, Lindenmeyer, Christina C., Boike, Justin R., Simonetto, Douglas A., Rahimi, Robert S., Jalal, Prasun K., Izzy, Manhal, Kriss, Michael S., Im, Gene Y., Lin, Ming V., Jou, Janice H., Fortune, Brett E., Cholankeril, George, Kuo, Alexander, Mahmud, Nadim, Kanwal, Fasiha, Saliba, Faouzi, Sundaram, Vinay, Artzner, Thierry, and Jalan, Rajiv

Published
2023
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12. List of contributors

Author

Abraldes, Juan Gonzalez, primary, Altieri, Mario, additional, Arroyo, Vicente, additional, Attia, Dina, additional, Baiges, Anna, additional, Baik, Soon Koo, additional, Betancourt, Fabian, additional, Chadha, Ryan, additional, Chahal, Daljeet, additional, Chen, Po-Hung, additional, Desai, Moreshwar S., additional, Doycheva, Iliana, additional, Fernandez, Javier, additional, Fouad, Yasser, additional, García-Pagán, Juan Carlos, additional, Gorgis, Noelle, additional, Gurram, Harini, additional, Hernández-Gea, Virginia, additional, Iqbal, Shaz, additional, Izzy, Manhal, additional, Jo, Jennifer, additional, Kang, Seong Hee, additional, Khalifa, Rofida, additional, Koseki, Masahiro, additional, Kuwabara, Masanari, additional, Lee, Samuel S., additional, Lisman, Ton, additional, Liu, Hongqun, additional, Luo, Xuefeng, additional, Magaz, Marta, additional, Marquez, Vladimir, additional, Moreau, Richard, additional, Nicoar-Farcu, Oana, additional, Niwa, Koichiro, additional, Okada, Atsushi, additional, Pollak, P. Timothy, additional, Saito, Yuki, additional, Singu, Bonifasius S., additional, Soy, Guillem, additional, Taniguchi, Tatsunori, additional, Turon, Fanny, additional, Valérie, Paradis, additional, VanWagner, Lisa B., additional, Verbeeck, Roger K., additional, Watt, Kymberly D., additional, Wong, Florence, additional, and Wray, Christopher L., additional

Published
2023
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14. Enhanced recovery for liver transplantation: recommendations from the 2022 International Liver Transplantation Society consensus conference

Author

Mayr, Andreas, Dominguez, Beatriz, Muller, Elmi, Rando, Karina, Enoch, Mary Anne, Tamir, Noam, Healy, Pamela, Manser, Tanja, Briggs, Tim, Chaudhary, Abhideep, Humar, Abhinav, Jafarian, Ali, Soin, Arvinder Singh, Eghtesad, Bijan, Miller, Charles, Cherqui, Daniel, Samuel, Didier, Broering, Dieter, Pomfret, Elizabeth, Villamil, Federico, Durand, Francois, Berlakovich, Gabriela, McCaughan, Geoffrey, Auzinger, Georg, Testa, Giuliano, Klintmalm, Goran, Belghiti, Jacques, Findlay, James, Lai, Jennifer, Fung, John, Klinck, John, Roberts, John, Liu, Linda, Cattral, Mark, Ghobrial, Mark, Selzner, Markus, Ramsay, Michael, Rela, Mohamed, Ascher, Nancy, Man, Nancy Kwan, Selzner, Nazia, Burra, Patrizia, Friend, Peter, Busuttil, Ronald, Hwang, Shin, McCluskey, Stuart, Mas, Valeria, Vohra, Vijay, Vij, Vivek, Merritt, William, Tokat, Yaman, Kang, Yoogoo, Chan, Albert, Mazzola, Alessandra, Hessheimer, Amelia, Rammohan, Ashwin, Hogan, Brian, Vinaixa, Carmen, Nasralla, David, Victor, David, De Martin, Eleonora, Alconchel, Felipe, Roll, Garrett, Kabacam, Gokhan, Sapisochin, Gonzalo, Campos-Varela, Isabel, Liu, Jiang, Patel, Madhukar S., Izzy, Manhal, Kalisvaart, Marit, Adams, Megan, Goldaracena, Nicholas, Tinguely, Pascale, Hernandez-Alejandro, Roberto, Chadha, Ryan, Shaker, Tamer Mahmoud, Klair, Tarunjeet S., Pan, Terry, Tanaka, Tomohiro, Yoon, Uzung, Kirchner, Varvara, Hannon, Vivienne, Cheah, Yee Lee, Frola, Carlo, Morkane, Clare, Milliken, Don, Lurje, Georg, Potts, Jonathan, Fernandez, Thomas, Badenoch, Adam, Mukhtar, Ahmed, Zanetto, Alberto, Montano-Loza, Aldo, Chieh, Alfred Kow Wei, Shetty, Amol, DeWolf, Andre, Olmos, Andrea, Mrzljak, Anna, Blasi, Annabel, Berzigotti, Annalisa, Malik, Ashish, Rajakumar, Akila, Davidson, Brian, O'Farrell, Bryan, Kotton, Camille, Imber, Charles, Kwon, Choon Hyuck David, Wray, Christopher, Ahn, Chul-Soo, Krenn, Claus, Quintini, Cristiano, Maluf, Daniel, Mina, Daniel Santa, Sellers, Daniel, Balci, Deniz, Patel, Dhupal, Rudow, Dianne LaPointe, Monbaliu, Diethard, Bezinover, Dmitri, Krzanicki, Dominik, Kim, Dong-Sik, Brombosz, Elizabeth, Blumberg, Emily, Weiss, Emmanuel, Wey, Emmanuel, Kaldas, Fady, Saliba, Faouzi, Pittau, Gabriella, Wagener, Gebhard, Song, Gi-Won, Biancofiore, Gianni, Crespo, Gonzalo, Rodríguez, Gonzalo, Palli, Graciela Martinez, McKenna, Gregory, Petrowsky, Henrik, Egawa, Hiroto, Montasser, Iman, Pirenne, Jacques, Eason, James, Guarrera, James, Pomposelli, James, Lerut, Jan, Emond, Jean, Boehly, Jennifer, Towey, Jennifer, Hillingsø, Jens G, de Jonge, Jeroen, Caicedo, Juan, Heimbach, Julie, Emamaullee, Juliet Ann, Bartoszko, Justyna, Ma, Ka Wing, Kronish, Kate, Forkin, Katherine T., Chok, Kenneth Siu Ho, Olthoff, Kim, Reyntjens, Koen, Lee, Kwang-Woong, Suh, Kyung-Suk, Denehy, Linda, van der Laan, Luc J.W., McCormack, Lucas, Gorvin, Lucy, Ruffolo, Luis, Bhat, Mamatha, Ramírez, María Amalia Matamoros, Londoño, Maria-Carlota, Gitman, Marina, Levstik, Mark, de Santibañes, Martin, Lindsay, Martine, Parotto, Matteo, Armstrong, Matthew, Kasahara, Mureo, Schofield, Nick, Rizkalla, Nicole, Akamatsu, Nobuhisa, Scatton, Olivier, Keskin, Onur, Imventarza, Oscar, Andacoglu, Oya, Muiesan, Paolo, Giorgio, Patricia, Northup, Patrick, Matins, Paulo, Abt, Peter, Newsome, Philip N, Dutkowski, Philipp, Bhangui, Pooja, Bhangui, Prashant, Tandon, Puneeta, Brustia, Raffaele, Planinsic, Raymond, Brown, Robert, Porte, Robert, Barth, Rolf, Ciria, Rubén, Florman, Sander, Dharancy, Sebastien, Pai, Sher-Lu, Yagi, Shintaro, Nadalin, Silvio, Chinnakotla, Srinath, Forbes, Stuart J, Rahman, Suehana, Hong, Suk Kyun, Liying, Sun, Orloff, Susan, Rubman, Susan, Eguchi, Susumu, Ikegami, Toru, Reichman, Trevor, Settmacher, Utz, Aluvihare, Varuna, Xia, Victor, Yoon, Young-In, Soejima, Yuji, Genyk, Yuri, Jalal, Arif, Borakati, Aditya, Gustar, Adrian, Mohamed, Ahmed, Ramirez, Alejandro, Rothnie, Alex, Scott, Aneya, Sharma, Anika, Munro, Annalise, Mahay, Arun, Liew, Belle, Hidalgo, Camila, Crouch, Cara, Yan, Cheung Tsz, Tschuor, Christoph, Shaw, Conrad, Schizas, Dimitrios, Fritche, Dominic, Huda, Fabia Ferdousi, Wells, Gemma, Farrer, Giselle, Kwok, Hiu Tat, Kostakis, Ioannis, Mestre-Costa, Joao, Fan, Ka Hay, Fan, Ka Siu, Fraser, Kyra, Jeilani, Lelia, Pang, Li, Lenti, Lorenzo, Kathirvel, Manikandan, Zachiotis, Marinos, Vailas, Michail, Milan, Michele Mazza, Elnagar, Mohamed, Alradhawi, Mohammad, Dimitrokallis, Nikolaos, Machairas, Nikolaos, Morare, Nolitha, Yeung, Oscar, Khanal, Pragalva, Satish, Pranav, Ghani, Shahi Abdul, Makhdoom, Shahroo, Arulrajan, Sithhipratha, Bogan, Stephanie, Pericleous, Stephanos, Blakemore, Timon, Otti, Vanessa, Lam, Walter, Jackson, Whitney, Abdi, Zakee, Pollok, Joerg M, Berenguer, Marina, Niemann, Claus U, Raptis, Dimitri A, and Spiro, Michael

Published
2023
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17. Safety and efficacy of continuous terlipressin infusion in HRS-AKI in a transplant population

Author

Reddy, K. Rajender, primary, Weinberg, Ethan M., additional, Gonzalez, Stevan A., additional, Izzy, Manhal J., additional, Simonetto, Douglas A., additional, Frederick, R. Todd, additional, Rubin, Raymond A., additional, Fricker, Zachary, additional, Ikahihifo-Bender, Jade, additional, Harte, Maggie, additional, Garcia, Sandra, additional, Campbell, Kathryn, additional, Olofson, Amy, additional, Razavi, Ryan F., additional, James, Janelle M., additional, Patel, Het, additional, Kim-Lee, Grace, additional, Witkiewicz, Sherry, additional, Tobin, William, additional, and Jamil, Khurram, additional

Published
2024
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26. Worldwide variations in COVID-19 vaccination policies and practices in liver transplant settings: results of a multi-society global survey

Author

Di Maira, Tommaso, primary, Vinaixa, Carmen, additional, Izzy, Manhal, additional, Paolo Russo, Francesco, additional, Kirchner, Varvara A., additional, Rammohan, Ashwin, additional, Belli, Luca Saverio, additional, Polak, Wojciech Grzegorz, additional, Berg, Thomas, additional, and Berenguer, Marina, additional

Published
2024
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27. Evaluation of terlipressin-related patient outcomes in hepatorenal syndrome-acute kidney injury using point-of-care echocardiography.

Author

Premkumar, Madhumita, Kajal, Kamal, Reddy, K. Rajender, Izzy, Manhal, Kulkarni, Anand V., Duseja, Ajay Kumar, Sihag, K. Bhupendra, Divyaveer, Smita, Gupta, Ankur, Taneja, Sunil, De, Arka, Verma, Nipun, Rathi, Sahaj, Bhujade, Harish, Chaluvashetty, Sreedhara B., Roy, Akash, Kumar, Vishesh, Siddhartha, Vuppada, Singh, Virendra, and Bahl, Ajay

Published
2024
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28. The novel SALT-M score predicts 1-year post-transplant mortality in patients with severe acute-on-chronic liver failure

Author

Hernaez, Ruben, primary, Karvellas, Constantine J., additional, Liu, Yan, additional, Sacleux, Sophie-Caroline, additional, Khemichian, Saro, additional, Stein, Lance L., additional, Shetty, Kirti, additional, Lindenmeyer, Christina C., additional, Boike, Justin R., additional, Simonetto, Douglas A., additional, Rahimi, Robert S., additional, Jalal, Prasun K., additional, Izzy, Manhal, additional, Kriss, Michael S., additional, Im, Gene Y., additional, Lin, Ming V., additional, Jou, Janice H., additional, Fortune, Brett E., additional, Cholankeril, George, additional, Kuo, Alexander, additional, Mahmud, Nadim, additional, Kanwal, Fasiha, additional, Saliba, Faouzi, additional, Sundaram, Vinay, additional, Artzner, Thierry, additional, Jalan, Rajiv, additional, Al Attar, Atef, additional, Kosari, Kambiz, additional, Garcia, Richard, additional, Salmastyan, Gevork, additional, Cranford, William, additional, Patel, Preet, additional, Xue, Pei, additional, Mishra, Soumya, additional, Parks, Madison, additional, Flocco, Gianina, additional, Gao, Jing, additional, Wu, Tiffany, additional, Thanneeru, Priya, additional, Reddy, Vikrant, additional, Hurtado, Mariana, additional, Mohamed, Islam, additional, Vyhmeister, Ross, additional, Lopez, Christine R., additional, Campbell, Braidie, additional, Winters, Adam C., additional, Simpson, Mary Ann, additional, and Ying, Xiaohan, additional

Published
2023
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32. Launch of the International Living Donor Liver Transplantation Outcomes Registry

Author

Staubli, Sebastian, primary, Grover, Alexander Steen, additional, Turner, Benedict R H, additional, Raptis, Dimitri A, additional, Spiro, Michael, additional, Tinguely, Pascale, additional, Berenguer, Marina, additional, Rela, Mohamed, additional, Raptis, Dimitri A., additional, Pomfret, Elizabeth, additional, Egawa, Hiroto, additional, Kim, Ki-Hun, additional, Bhangui, Prashant, additional, Yi, Nam J., additional, Chaudhary, Abhideep, additional, Humar, Abhinav, additional, Shaked, Abraham, additional, Chan, Albert, additional, Chieh, Alfred K.W., additional, Jafarian, Ali, additional, Soin, Arvinder S., additional, Chen, Chao-Long, additional, Miller, Charles, additional, Wang, Chih-Chi, additional, Azoulay, Daniel, additional, Cherqui, Daniel, additional, Balci, Deniz, additional, Joo, Dong J., additional, Testa, Giulano, additional, Kabacam, Gokhan, additional, Sapisochin, Gonzalo, additional, Eilers, Helge, additional, Ozden, Ilgin, additional, Lerut, Jan, additional, Roberts, John P., additional, Dong, Jia-Hong, additional, Liu, Jiang, additional, Olthoff, Kim, additional, Hasegawa, Kiyoshi, additional, Man, Kwan, additional, Patel, Madhukar S., additional, Cattral, Mark, additional, Malago, Massimo, additional, Kasahara, Mureo, additional, Ascher, Nancy, additional, Selzner-Malekkiani, Nazia, additional, Bhangui, Pooja, additional, Jalan, Rajiv, additional, Kamel, Refaat, additional, Adam, Rene, additional, Troisi, Roberto I., additional, Nadalin, Silvio, additional, Asthana, Sonal, additional, McCluskey, Stuart A., additional, Gupta, Subhash, additional, Eguchi, Susumu, additional, Pan, Terry, additional, Wong, Tiffany C.L., additional, Vohra, Vijay, additional, Vij, Vivek, additional, Andraus, Wellington, additional, Tokat, Yaman, additional, Soejima, Yuji, additional, Mayr, Andreas, additional, Dominguez, Beatriz, additional, Muller, Elmi, additional, Rando, Karina, additional, Rammoha, Ashwin, additional, Roll, Garrett, additional, Izzy, Manhal, additional, De Santibanes, Martin, additional, Andacoglu, Oya, additional, Kirchner, Varvara A., additional, De Martin, Eleonora, additional, Fernandez, Thomas, additional, Turner, Benedict R.H., additional, Chikkala, Bhargava, additional, Hidalgo-Salina, Camila, additional, Mellul, Emmanuel, additional, Syeda, Gulbahar, additional, Kantsedikas, Ilya, additional, Patel, Krishnakumure, additional, Zachiotis, Marinos, additional, Raja, Meera, additional, Reji, Nidhi, additional, Machairas, Nikolaos, additional, Staubli, Sebastian, additional, Ghani, Shahi A., additional, Grover, Steen, additional, Bousi, Stelios-Elion, additional, and Oberkofler, Christian E., additional

Published
2023
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34. Addressing the Burden and Management Strategies for Disparities and Inequities Among Liver Transplant Professionals: The ILTS Experience

Author

Andacoglu, Oya, primary, Izzy, Manhal, additional, Adelmann, Dieter, additional, Aguilera, Victoria, additional, Becchetti, Chiara, additional, Berenguer, Marina, additional, Berlakovich, Gabriella A., additional, Ghosh, Simantika, additional, Giorgakis, Emmanouil, additional, Kemmer, Nyingi, additional, Lunsford, Keri E., additional, Montasser, Iman F., additional, Montenovo, Martin I., additional, Mrzljak, Anna, additional, Pai, Sher-Lu, additional, Scalera, Irene, additional, and Selzner, Nazia, additional

Published
2023
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35. Strategies to eliminate hepatitis C virus infection in the Americas

Author

Diaz, Luis Antonio, primary, García, Sergio, additional, Khan, Rayan, additional, Ayares, Gustavo, additional, Monasterio, Javier Uribe, additional, Idalsoaga, Francisco, additional, Fuentes, Eduardo, additional, Medel, María Paz, additional, Ramirez, Carolina, additional, Lazo, Mariana, additional, Ferreccio, Catterina, additional, Mendizabal, Manuel, additional, Dirchwolf, Melisa, additional, Guerra, Patricia, additional, Oliveira, Claudia, additional, Pessoa, Mário, additional, Álvares-da-Silva, Mario, additional, Sebastiani, Giada, additional, Brahmania, Mayur, additional, Ramji, Alnoor, additional, Niazi, Mina, additional, Ko, Hin HIn, additional, Feld, Jordan J., additional, Restrepo, Juan Carlos, additional, Ramirez, Wagner, additional, Alfaro, Omar, additional, Castellanos-Fernández, Marlen, additional, Carrera, Enrique, additional, Aguirre, Jose Roberto, additional, Maldonado Cardona, Katherine Emilia, additional, Sanchez, Abel, additional, Sánchez, Marco, additional, Andara, Maria Teresa, additional, Castro-Narro, Graciela, additional, Chávez-Tapia, Norberto Carlos, additional, Méndez-Sánchez, Nahum, additional, Adames, Enrique, additional, Lombardo, Julissa, additional, Girala, Marcos, additional, Morán, Elias, additional, Padilla, P. Martin, additional, Diaz-Ferrer, Javier, additional, Tagle, Martin, additional, Mainardi, Victoria, additional, Hernandez, Nélia, additional, Martinez, Edmundo, additional, Alvarado-Tapias, Edilmar, additional, Robert, Leon, additional, Hernandez-Tejero, Maria, additional, De Sicilia, Mauricio Garcia Saenz, additional, Zhang, Wei, additional, Bajaj, Jasmohan S., additional, Tapper, Elliot, additional, Izzy, Manhal, additional, Gish, Robert G., additional, Attar, Bashar, additional, Cotter, Thomas, additional, Kamath, Patrick S., additional, Singal, Ashwani, additional, Bataller, Ramon, additional, Mezzano, Gabriel, additional, Soza, Alejandro, additional, Lazarus, Jeffrey, additional, Arrese, Marco, additional, and Arab, Juan Pablo, additional

Published
2023
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36. Safety and efficacy of continuous infusion terlipressin in acute kidney injury-hepatorenal syndrome: the Infuse study

Author

Reddy, K. Rajender, primary, Weinberg, Ethan, additional, Gonzalez, Stevan, additional, Izzy, Manhal, additional, Simonetto, Douglas, additional, Frederick, Richard, additional, Rubin, Raymond, additional, Fricker, Zachary, additional, Kim-Lee, Grace, additional, Witkiewicz, Sherry, additional, Tobin, William, additional, and Jamil, Khurram, additional

Published
2023
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38. O- 23 STRATEGIES TO ELIMINATE HEPATITIS C VIRUS INFECTION IN THE AMERICAS

Author

Díaz, Luis Antonio, García, Sergio, Khan, Rayan, Ayares, Gustavo, Uribe, Javier, Idalsoaga, Francisco, Fuentealba, José Miguel, Fuentes, Eduardo, Maldonado, Katherine, Lazo, Mariana, Ferreccio, Catterina, Mendizabal, Manuel, Dirchwolf, Melisa, Guerra, Patricia, Oliveira, Claudia P., Guimarães, Mario, Reis, Mario, Sebastiani, Giada, Brahmania, Mayur, Ramji, Alnoor, Niazi, Mina, Ko, Hin Hin, Feld, Jordan, Restrepo, Juan Carlos, Ramírez, Wagner, Alfaro, Omar, Castellanos-Fernández, Marlen, Carrera, Enrique, Ayala, José Roberto Aguirre, Sánchez, Abel, Sánchez, Marco, Andara, María Teresa, Castro, Graciela, Chavez-Tapia, Norberto, Mendez-Sanchez, Nahum, Adames, Enrique, Lombardo, Julissa, Girala, Marcos, Morán, Elías, Padilla-Machaca, Martin, Díaz, Javier, Tagle, Martín, Mainardi, Victoria, Hernandez, Nelia, Martínez, Edmundo, Alvarado-Tapias, Edilmar, Leon, Roberto, Talal, Andrew, Thomas, Emmanuel, Springer, Sandra, Garcia-Saenz-de-Sicilia, Mauricio, Zhang, Wei, Bajaj, Jasmohan, Tapper, Elliot B., Izzy, Manhal J., Gish, Robert G., Attar, Bashar, Cotter, Thomas G., Lucey, Michael R., Kamath, Patrick S., Singal, Ashwani K., Bataller, Ramón, Mezzano, Gabriel, Soza, Alejandro, Lazarus, Jeffrey V., Arrese, Marco, and Arab, Juan Pablo

Published
2024
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43. Cirrhotic cardiomyopathy influences clinical outcomes and enhances performance of conventional risk prediction models in acute‐on‐chronic liver failure with severe sepsis.

Author

Kajal, Kamal, Premkumar, Madhumita, Izzy, Manhal, Kulkarni, Anand V., Duseja, Ajay Kumar, Divyaveer, Smita, Loganathan, Sekar, Sihag, Bhupendra, Gupta, Ankur, Bahl, Ajay, Rathi, Sahaj, Taneja, Sunil, De, Arka, Verma, Nipun, Sharma, Navneet, Kaur, Harpreet, Zohmangaihi, Deepy, Kumar, Vishesh, Bhujade, Harish, and Chaluvashetty, Sreedhara B.

Subjects
LIVER failure, BRAIN natriuretic factor, PREDICTION models, SEPSIS, INTENSIVE care units
Abstract

Summary: Background: Point‐of‐care echocardiography (POC‐Echo) is an essential intensive care hemodynamic monitoring tool. Aims: To assess POC‐Echo parameters [i.e., cardiac index (CI), systemic vascular resistance index (SVRI) and cirrhotic cardiomyopathy (CCM) markers] and serum biomarkers in predicting circulatory failure (need for vasopressors) and mortality in patients with acute‐on‐chronic liver failure (ACLF) having sepsis‐induced hypotension. Methods: We performed serial POC‐Echo within 6 hours (h) of presentation and subsequently at 24, 48 and 72 h in patients with ACLF and sepsis‐induced hypotension admitted to our liver intensive care unit. Clinical data, POC‐Echo data and serum biomarkers were collected prospectively. Results: We enrolled 120 patients [59% men, aged 49 ± 12 years, 56% alcohol‐related disease and median MELDNa of 30 (27–32)], of whom 68 (56.6%) had circulatory failure, with overall mortality of 60%. CCM was present in 52.5%. The predictors of circulatory failure were CI (aHR −1.5; p = 0.021), N‐terminal brain natriuretic peptide (aHR −1.1; p = 0.007) and CCM markers; e′ septal mitral velocity (aHR −0.5; p = 0.039) and E/e′ ratio (aHR −1.2; p = 0.045). Reduction in CI by 20% and SVRI by 15% at 72 h predicted mortality with a sensitivity of 84% and 72%, and specificity 76% and 65%, respectively (p < 0.001). The MELD‐CCM model and CLIF‐CCM model were computed as MELDNa + 1.815 × E/e′ (septal) + 0.402 × e′ (septal) and CLIF‐C ACLF + 1.815 × E/e′ (septal) + 0.402 × e′ (septal), respectively, based on multivariable logistic regression. Both scores outperformed MELDNa (z‐score = −2.073, p = 0.038) and CLIF‐C ACLF score (z score = −2.683, p‐value = 0.007), respectively, in predicting 90‐day mortality. Conclusion: POC‐Echo measurements such as CCM markers (E/e' and e' velocity) and change in CI reliably predict circulatory failure and mortality in ACLF with severe sepsis. CCM markers significantly enhanced the CLIF‐C ACLF and MELDNa predictive performance. [ABSTRACT FROM AUTHOR]

Published
2023
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45. Enhanced recovery for liver transplantation: recommendations from the 2022 International Liver Transplantation Society consensus conference

Author

Pollok, Joerg M, primary, Tinguely, Pascale, additional, Berenguer, Marina, additional, Niemann, Claus U, additional, Raptis, Dimitri A, additional, Spiro, Michael, additional, Mayr, Andreas, additional, Dominguez, Beatriz, additional, Muller, Elmi, additional, Rando, Karina, additional, Enoch, Mary Anne, additional, Tamir, Noam, additional, Healy, Pamela, additional, Manser, Tanja, additional, Briggs, Tim, additional, Chaudhary, Abhideep, additional, Humar, Abhinav, additional, Jafarian, Ali, additional, Soin, Arvinder Singh, additional, Eghtesad, Bijan, additional, Miller, Charles, additional, Cherqui, Daniel, additional, Samuel, Didier, additional, Broering, Dieter, additional, Pomfret, Elizabeth, additional, Villamil, Federico, additional, Durand, Francois, additional, Berlakovich, Gabriela, additional, McCaughan, Geoffrey, additional, Auzinger, Georg, additional, Testa, Giuliano, additional, Klintmalm, Goran, additional, Belghiti, Jacques, additional, Findlay, James, additional, Lai, Jennifer, additional, Fung, John, additional, Klinck, John, additional, Roberts, John, additional, Liu, Linda, additional, Cattral, Mark, additional, Ghobrial, Mark, additional, Selzner, Markus, additional, Ramsay, Michael, additional, Rela, Mohamed, additional, Ascher, Nancy, additional, Man, Nancy Kwan, additional, Selzner, Nazia, additional, Burra, Patrizia, additional, Friend, Peter, additional, Busuttil, Ronald, additional, Hwang, Shin, additional, McCluskey, Stuart, additional, Mas, Valeria, additional, Vohra, Vijay, additional, Vij, Vivek, additional, Merritt, William, additional, Tokat, Yaman, additional, Kang, Yoogoo, additional, Chan, Albert, additional, Mazzola, Alessandra, additional, Hessheimer, Amelia, additional, Rammohan, Ashwin, additional, Hogan, Brian, additional, Vinaixa, Carmen, additional, Nasralla, David, additional, Victor, David, additional, De Martin, Eleonora, additional, Alconchel, Felipe, additional, Roll, Garrett, additional, Kabacam, Gokhan, additional, Sapisochin, Gonzalo, additional, Campos-Varela, Isabel, additional, Liu, Jiang, additional, Patel, Madhukar S., additional, Izzy, Manhal, additional, Kalisvaart, Marit, additional, Adams, Megan, additional, Goldaracena, Nicholas, additional, Hernandez-Alejandro, Roberto, additional, Chadha, Ryan, additional, Shaker, Tamer Mahmoud, additional, Klair, Tarunjeet S., additional, Pan, Terry, additional, Tanaka, Tomohiro, additional, Yoon, Uzung, additional, Kirchner, Varvara, additional, Hannon, Vivienne, additional, Cheah, Yee Lee, additional, Frola, Carlo, additional, Morkane, Clare, additional, Milliken, Don, additional, Lurje, Georg, additional, Potts, Jonathan, additional, Fernandez, Thomas, additional, Badenoch, Adam, additional, Mukhtar, Ahmed, additional, Zanetto, Alberto, additional, Montano-Loza, Aldo, additional, Chieh, Alfred Kow Wei, additional, Shetty, Amol, additional, DeWolf, Andre, additional, Olmos, Andrea, additional, Mrzljak, Anna, additional, Blasi, Annabel, additional, Berzigotti, Annalisa, additional, Malik, Ashish, additional, Rajakumar, Akila, additional, Davidson, Brian, additional, O'Farrell, Bryan, additional, Kotton, Camille, additional, Imber, Charles, additional, Kwon, Choon Hyuck David, additional, Wray, Christopher, additional, Ahn, Chul-Soo, additional, Krenn, Claus, additional, Quintini, Cristiano, additional, Maluf, Daniel, additional, Mina, Daniel Santa, additional, Sellers, Daniel, additional, Balci, Deniz, additional, Patel, Dhupal, additional, Rudow, Dianne LaPointe, additional, Monbaliu, Diethard, additional, Bezinover, Dmitri, additional, Krzanicki, Dominik, additional, Kim, Dong-Sik, additional, Brombosz, Elizabeth, additional, Blumberg, Emily, additional, Weiss, Emmanuel, additional, Wey, Emmanuel, additional, Kaldas, Fady, additional, Saliba, Faouzi, additional, Pittau, Gabriella, additional, Wagener, Gebhard, additional, Song, Gi-Won, additional, Biancofiore, Gianni, additional, Crespo, Gonzalo, additional, Rodríguez, Gonzalo, additional, Palli, Graciela Martinez, additional, McKenna, Gregory, additional, Petrowsky, Henrik, additional, Egawa, Hiroto, additional, Montasser, Iman, additional, Pirenne, Jacques, additional, Eason, James, additional, Guarrera, James, additional, Pomposelli, James, additional, Lerut, Jan, additional, Emond, Jean, additional, Boehly, Jennifer, additional, Towey, Jennifer, additional, Hillingsø, Jens G, additional, de Jonge, Jeroen, additional, Caicedo, Juan, additional, Heimbach, Julie, additional, Emamaullee, Juliet Ann, additional, Bartoszko, Justyna, additional, Ma, Ka Wing, additional, Kronish, Kate, additional, Forkin, Katherine T., additional, Chok, Kenneth Siu Ho, additional, Olthoff, Kim, additional, Reyntjens, Koen, additional, Lee, Kwang-Woong, additional, Suh, Kyung-Suk, additional, Denehy, Linda, additional, van der Laan, Luc J.W., additional, McCormack, Lucas, additional, Gorvin, Lucy, additional, Ruffolo, Luis, additional, Bhat, Mamatha, additional, Ramírez, María Amalia Matamoros, additional, Londoño, Maria-Carlota, additional, Gitman, Marina, additional, Levstik, Mark, additional, de Santibañes, Martin, additional, Lindsay, Martine, additional, Parotto, Matteo, additional, Armstrong, Matthew, additional, Kasahara, Mureo, additional, Schofield, Nick, additional, Rizkalla, Nicole, additional, Akamatsu, Nobuhisa, additional, Scatton, Olivier, additional, Keskin, Onur, additional, Imventarza, Oscar, additional, Andacoglu, Oya, additional, Muiesan, Paolo, additional, Giorgio, Patricia, additional, Northup, Patrick, additional, Matins, Paulo, additional, Abt, Peter, additional, Newsome, Philip N, additional, Dutkowski, Philipp, additional, Bhangui, Pooja, additional, Bhangui, Prashant, additional, Tandon, Puneeta, additional, Brustia, Raffaele, additional, Planinsic, Raymond, additional, Brown, Robert, additional, Porte, Robert, additional, Barth, Rolf, additional, Ciria, Rubén, additional, Florman, Sander, additional, Dharancy, Sebastien, additional, Pai, Sher-Lu, additional, Yagi, Shintaro, additional, Nadalin, Silvio, additional, Chinnakotla, Srinath, additional, Forbes, Stuart J, additional, Rahman, Suehana, additional, Hong, Suk Kyun, additional, Liying, Sun, additional, Orloff, Susan, additional, Rubman, Susan, additional, Eguchi, Susumu, additional, Ikegami, Toru, additional, Reichman, Trevor, additional, Settmacher, Utz, additional, Aluvihare, Varuna, additional, Xia, Victor, additional, Yoon, Young-In, additional, Soejima, Yuji, additional, Genyk, Yuri, additional, Jalal, Arif, additional, Borakati, Aditya, additional, Gustar, Adrian, additional, Mohamed, Ahmed, additional, Ramirez, Alejandro, additional, Rothnie, Alex, additional, Scott, Aneya, additional, Sharma, Anika, additional, Munro, Annalise, additional, Mahay, Arun, additional, Liew, Belle, additional, Hidalgo, Camila, additional, Crouch, Cara, additional, Yan, Cheung Tsz, additional, Tschuor, Christoph, additional, Shaw, Conrad, additional, Schizas, Dimitrios, additional, Fritche, Dominic, additional, Huda, Fabia Ferdousi, additional, Wells, Gemma, additional, Farrer, Giselle, additional, Kwok, Hiu Tat, additional, Kostakis, Ioannis, additional, Mestre-Costa, Joao, additional, Fan, Ka Hay, additional, Fan, Ka Siu, additional, Fraser, Kyra, additional, Jeilani, Lelia, additional, Pang, Li, additional, Lenti, Lorenzo, additional, Kathirvel, Manikandan, additional, Zachiotis, Marinos, additional, Vailas, Michail, additional, Milan, Michele Mazza, additional, Elnagar, Mohamed, additional, Alradhawi, Mohammad, additional, Dimitrokallis, Nikolaos, additional, Machairas, Nikolaos, additional, Morare, Nolitha, additional, Yeung, Oscar, additional, Khanal, Pragalva, additional, Satish, Pranav, additional, Ghani, Shahi Abdul, additional, Makhdoom, Shahroo, additional, Arulrajan, Sithhipratha, additional, Bogan, Stephanie, additional, Pericleous, Stephanos, additional, Blakemore, Timon, additional, Otti, Vanessa, additional, Lam, Walter, additional, Jackson, Whitney, additional, and Abdi, Zakee, additional

Published
2023
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46. Management of cardiac diseases in liver transplant recipients: Comprehensive review and multidisciplinary practice-based recommendations

Author

Izzy, Manhal, primary, Fortune, Brett E., additional, Serper, Marina, additional, Bhave, Nicole, additional, deLemos, Andrew, additional, Gallegos-Orozco, Juan F., additional, Guerrero-Miranda, Cesar, additional, Hall, Shelley, additional, Harinstein, Matthew E., additional, Karas, Maria G., additional, Kriss, Michael, additional, Lim, Nicholas, additional, Palardy, Maryse, additional, Sawinski, Deirdre, additional, Schonfeld, Emily, additional, Seetharam, Anil, additional, Sharma, Pratima, additional, Tallaj, Jose, additional, Dadhania, Darshana M., additional, and VanWagner, Lisa B., additional

Published
2022
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47. Addressing the Burden and Management Strategies for Disparities and Inequities Among Liver Transplant Professionals: The ILTS Experience

Author

Andacoglu, Oya, Izzy, Manhal, Adelmann, Dieter, Aguilera, Victoria, Becchetti, Chiara, Berenguer, Marina, Berlakovich, Gabriella A, Ghosh, Simantika, Giorgakis, Emmanouil, Kemmer, Nyingi, Lunsford, Keri E, Montasser, Iman F, Montenovo, Martin I, Mrzljak, Anna, Pai, Sher-Lu, Scalera, Irene, and Selzner, Nazia

Subjects
610 Medicine & health
Abstract

Medical professional environments are becoming increasingly multicultural, international, and diverse in terms of its specialists. Many transplant professionals face challenges related to gender, sexual orientation or racial background in their work environment or experience inequities involving access to leadership positions, professional promotion, and compensation. These circumstances not infrequently become a major source of work-related stress and burnout for these disadvantaged, under-represented transplant professionals. In this review, we aim to 1) discuss the current perceptions regarding disparities among liver transplant providers 2) outline the burden and impact of disparities and inequities in the liver transplant workforce 3) propose potential solutions and role of professional societies to mitigate inequities and maximize inclusion within the transplant community.

Published
2023
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48. Multidisciplinary Approach to Improving Safety in Transesophageal Echocardiography in Patients With Relative Contraindications

Author

Mishra, Kelly L., primary, Baker, Michael T., additional, Siegrist, Kara K., additional, Liao, Alice, additional, Scanga, Andrew E., additional, Naik, Rishi, additional, Izzy, Manhal, additional, Spann, Matthew D., additional, Gillaspie, Erin A., additional, Gonzales, Holly M., additional, and Mendes, Lisa A., additional

Published
2022
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