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International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 13, 12, 13A12O: 1-5

International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 13, 12, 13A12S: 1-8

Various feed additives are used to increase productivity in poultry farming. The purpose of our research was to study the effectiveness of the developed and patented mineral feed additive “Cu-Active” for the prevention of hypocuporosis, increasing the performance and meat quality of broiler chickens. The research work was carried out in the laboratories of the Vitebsk State Academy of Veterinary Medicine and at the enterprise of ОАО “Poultry Farm “Rassvet”. It has been established that the patented mineral feed additive “Cu-Active” is not toxic for the protozoa Tetrahymena pyriformis and has an adsorption activity against sanitary-indicatory microorganisms (the number of mesophilic aerobic and facultative anaerobic microorganisms) at a level of 10.8 mg/g. The experimental poultry meat is of good quality according to organoleptic indices. The resulting carcasses meet the requirements of Grade I. Carcass yield - 71.0%. Saturation of the body with copper contributed to an increase in the natural resistance of the experimental poultry, a decrease in endogenous intoxication and the intensity of natural blood serum fluorescence, and, consequently, the normalization of the liver tissue functional activity. The introduction of a patented additive to compound feed for broiler chickens on the poultry farm contributes to an increase in average daily gains – by 1.9%, ensuring the poultry safety by at least 96.6% and reducing feed consumption by 4.1%. The level of profitability of poultry meat production increases by 0.51%. We recommend introducing the patented additive “Cu-Active” into compound feed for poultry in order to prevent microelementoses, hypocuporosis in particular, at a dose of 0.005%.

Nitric oxide (NO) is intensively synthesized in the embryo of birds. There is evidence that NO mediates myogenesis at the embryonic stage. In this regard, it might be possible to control muscle development and meat productivity by modulating NO synthesis. Using high-precision and a highly sensitive enzymatic sensor, the authors found that it is not the rate of synthesis that correlates with meat productivity, but the rate of NO oxidation to nitrate, which occurs in the tissues of the embryo. In broilers, it is several orders of magnitude higher than in layers. This indicator is solely due to the characteristics of embryonic tissues and is allelically determined. In-ovo arginine supplementation, a source of NO, did not lead to a significant increase in its synthesis and oxidation, but occasionally increased live weight gain, which was likely associated with a deficiency of free arginine and was not directly related to the effect of nitric oxide. Exogenous NO donors were oxidized with the same intensity as endogenous donors. These compounds did not have a significant effect on growth rate. Also, a reduction of 50% in the rate of NO synthesis under the action of a NO synthase inhibitor did not affect this parameter. Thus, regulation of poultry meat productivity is possible by modulating gene expression related to embryonic NO oxidation and ensuring an optimal amino acid and energy equilibrium, rather than by promoting embryonic NO synthesis. Keywords: Nitric oxide (NO), NO donor compounds, nitrate, arginine, live weight

The recommendations summarize the results of the use of feed additives (ASD-2F, vitamin preparations, antioxidants, prebiotics) that stimulate the productivity and preservation of poultry, the production of quality products, both under normal conditions of feeding and keeping the bird, and in stressful situations.

International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 11, 15, 11A15U: 1-6

International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 11, 16, 11A16L: 1-9