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309 results on '"Itani, M."'

3. Comprehensive Analysis of Adverse Events Associated with Gastric Peroral Endoscopic Myotomy: An International Multicenter Study

Author

Ichkhanian, Y., Vosoughi, K., Aghaie Meybodi, M., Jacques, J., Sethi, A., Patel, A. A., Aadam, A. A., Triggs, J. R., Bapaye, A., Dorwat, S., Benias, P., Chaves, D. M., Barret, M., Law, R. J., Browers, N., Pioche, M., Draganov, P. V., Kotzev, A., Estremera, F., Albeniz, E., Ujiki, M. B., Callahan, Z. M., Itani, M. I., Brewer, O. G., and Khashab, M. A.

Published
2021
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5. Characterization of adnexal lesions using photoacoustic imaging to improve ultrasound O‐RADS risk assessment

Author

Zhu, Q., primary, L., Hongbo, additional, Middleton, W. D., additional, Itani, M., additional, Hagemann, I. S., additional, Hagemann, A. R., additional, Hoegger, M. J., additional, Thaker, P. H., additional, Kuroki, L. M., additional, McCourt, C. K., additional, Mutch, D. G., additional, Powell, M. A., additional, and Siegel, C. L., additional

Published
2023
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8. Characterization of adnexal lesions using photoacoustic imaging to improve sonographic O‐RADS risk assessment.

Author

Zhu, Q., Luo, H., Middleton, W. D., Itani, M., Hagemann, I. S., Hagemann, A. R., Hoegger, M. J., Thaker, P. H., Kuroki, L. M., MCourt, C. K., Mutch, D. G., Powell, M. A., and Siegel, C. L.

Subjects
ADNEXAL diseases, FALLOPIAN tubes, RISK assessment, LOGISTIC regression analysis, REGRESSION analysis, SURGICAL pathology, ACOUSTIC imaging
Abstract

Objective: To assess the impact of photoacoustic imaging (PAI) on the assessment of ovarian/adnexal lesion(s) of different risk categories using the sonographic ovarian‐adnexal imaging‐reporting‐data system (O‐RADS) in women undergoing planned oophorectomy. Method: This prospective study enrolled women with ovarian/adnexal lesion(s) suggestive of malignancy referred for oophorectomy. Participants underwent clinical ultrasound (US) examination followed by coregistered US and PAI prior to oophorectomy. Each ovarian/adnexal lesion was graded by two radiologists using the US O‐RADS scale. PAI was used to compute relative total hemoglobin concentration (rHbT) and blood oxygenation saturation (%sO2) colormaps in the region of interest. Lesions were categorized by histopathology into malignant ovarian/adnexal lesion, malignant Fallopian tube only and several benign categories, in order to assess the impact of incorporating PAI in the assessment of risk of malignancy with O‐RADS. Malignant and benign histologic groups were compared with respect to rHbT and %sO2 and logistic regression models were developed based on tumor marker CA125 alone, US‐based O‐RADS alone, PAI‐based rHbT with %sO2, and the combination of CA125, O‐RADS, rHbT and %sO2. Areas under the receiver‐operating‐characteristics curve (AUC) were used to compare the diagnostic performance of the models. Results: There were 93 lesions identified on imaging among 68 women (mean age, 52 (range, 21–79) years). Surgical pathology revealed 14 patients with malignant ovarian/adnexal lesion, two with malignant Fallopian tube only and 52 with benign findings. rHbT was significantly higher in malignant compared with benign lesions. %sO2 was lower in malignant lesions, but the difference was not statistically significant for all benign categories. Feature analysis revealed that rHbT, CA125, O‐RADS and %sO2 were the most important predictors of malignancy. Logistic regression models revealed an AUC of 0.789 (95% CI, 0.626–0.953) for CA125 alone, AUC of 0.857 (95% CI, 0.733–0.981) for O‐RADS only, AUC of 0.883 (95% CI, 0.760–1) for CA125 and O‐RADS and an AUC of 0.900 (95% CI, 0.815–0.985) for rHbT and %sO2 in the prediction of malignancy. A model utilizing all four predictors (CA125, O‐RADS, rHbT and %sO2) achieved superior performance, with an AUC of 0.970 (95% CI, 0.932–1), sensitivity of 100% and specificity of 82%. Conclusions: Incorporating the additional information provided by PAI‐derived rHbT and %sO2 improves significantly the performance of US‐based O‐RADS in the diagnosis of adnexal lesions. © 2023 International Society of Ultrasound in Obstetrics and Gynecology. [ABSTRACT FROM AUTHOR]

Published
2023
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11. Correction to: Comprehensive analysis of adverse events associated with gastric peroral endoscopic myotomy: an international multicenter study

Author

Ichkhanian, Y., Vosoughi, K., Aghaie Meybodi, M., Jacques, J., Sethi, A., Patel, A. A., Aadam, A. A., Triggs, J. R., Bapaye, A., Dorwat, S., Benias, P., Chaves, D. M., Barret, M., Law, R. J., Browers, N., Pioche, M., Draganov, P. V., Kotzev, A., Estremera, F., Albeniz, E., Ujiki, M. B., Callahan, Z. M., Itani, M. I., Brewer, O. G., and Khashab, M. A.

Published
2021
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12. Evaluation of competency-driven training for facilitators delivering a psychological intervention for children in Lebanon: a proof-of-concept study

Author

Jordans, M. J. D., primary, Steen, F., additional, Koppenol-Gonzalez, G. V., additional, El Masri, R., additional, Coetzee, A. R., additional, Chamate, S., additional, Ghatasheh, M., additional, Pedersen, G. A., additional, Itani, M., additional, El Chammay, R., additional, Schafer, A., additional, and Kohrt, B. A., additional

Published
2022
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15. Diagnosis and prevalence of diabetic polyneuropathy: a cross‐sectional study of Danish patients with type 2 diabetes

Author

Gylfadottir, S. S., primary, Itani, M., additional, Krøigård, T., additional, Kristensen, A. G., additional, Christensen, D. H., additional, Nicolaisen, S. K., additional, Karlsson, P., additional, Callaghan, B. C., additional, Bennett, D. L., additional, Andersen, H., additional, Tankisi, H., additional, Nielsen, J. S., additional, Andersen, N. T., additional, Jensen, T. S., additional, Thomsen, R. W., additional, Sindrup, S. H., additional, and Finnerup, N. B., additional

Published
2020
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17. Correction to: Comprehensive analysis of adverse events associated with gastric peroral endoscopic myotomy: an international multicenter study

Author

Ichkhanian, Y., primary, Vosoughi, K., additional, Aghaie Meybodi, M., additional, Jacques, J., additional, Sethi, A., additional, Patel, A. A., additional, Aadam, A. A., additional, Triggs, J. R., additional, Bapaye, A., additional, Dorwat, S., additional, Benias, P., additional, Chaves, D. M., additional, Barret, M., additional, Law, R. J., additional, Browers, N., additional, Pioche, M., additional, Draganov, P. V., additional, Kotzev, A., additional, Estremera, F., additional, Albeniz, E., additional, Ujiki, M. B., additional, Callahan, Z. M., additional, Itani, M. I., additional, Brewer, O. G., additional, and Khashab, M. A., additional

Published
2020
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18. Comprehensive Analysis of Adverse Events Associated with Gastric Peroral Endoscopic Myotomy: An International Multicenter Study

Author

Ichkhanian, Y., primary, Vosoughi, K., additional, Aghaie Meybodi, M., additional, Jacques, J., additional, Sethi, A., additional, Patel, A. A., additional, Aadam, A. A., additional, Triggs, J. R., additional, Bapaye, A., additional, Dorwat, S., additional, Benias, P., additional, Chaves, D. M., additional, Barret, M., additional, Law, R. J., additional, Browers, N., additional, Pioche, M., additional, Draganov, P. V., additional, Kotzev, A., additional, Estremera, F., additional, Albeniz, E., additional, Ujiki, M. B., additional, Callahan, Z. M., additional, Itani, M. I., additional, Brewer, O. G., additional, and Khashab, M. A., additional

Published
2020
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23. Dynamic single node failure recovery in distributed storage systems

Author

Itani, M., Sharafeddine, S., Elkabani, I., Itani, M., Sharafeddine, S., and Elkabani, I.

Abstract

With the emergence of many erasure coding techniques that help provide reliability in practical distributed storage systems, we use fractional repetition coding on the given data and optimize the allocation of data blocks on system nodes in a way that minimizes the system repair cost. We selected fractional repetition coding due to its simple repair mechanism that minimizes the repair and disk access bandwidths together with the property of un-coded repair process. To minimize the system repair cost, we formulate our problem using incidence matrices and solve it heuristically using genetic algorithms for all possible cases of single node failures. We then address three practical extensions that respectively account for newly arriving blocks, newly arriving nodes and variable priority files. A re-optimization mechanism for the storage allocation matrix is proposed for the first two extensions that can be easily implemented in real time without the need to redistribute original on-node blocks. The third extension is addressed by implementing variable fractional repetition codes which is shown to achieve significant cost reduction. The contributions of the paper are four fold: (i) generating an optimized block distribution scheme among the nodes of a given data center for fixed and variable size blocks; (ii) optimization of storage allocation under dynamic environments with data block arrivals; (iii) optimization of storage allocation with newly added storage nodes; and (iv) generating an effective block distribution scheme among the nodes by accounting for varying priorities among data blocks. We present a wide range of results for the various proposed algorithms and considered scenarios to quantify the achievable performance gains.

Published
2018

29. Compression of the material characteristics of steel, aluminum, wood and woven graphite epoxy composites in response to high strain rate load

Author

Allazadeh, M. R., Itani, M. K., and Wosu, S. N.

Subjects
TJ
Abstract

The stresses developed in the material by impact load are analyzed experimentally, numerically, and analytically for specimens out of steel, aluminum, wood and woven graphite epoxy composites to investigate the material response to high strain rate stresses for aforementioned materials. The applied strain rates in experiments were set to be within 950 and 3500 s-1. The thin circular shape specimens were examined with high strain rate laboratory tests using the perforation split Hopkinson pressure bar (P-SHPB) with dimensional ratio accepted for One-dimensional stress analysis hypothesis. The article describes analytical solutions for one dimensional in detail to be implemented for numerical analyzing via trapezoid computation. The graphs of the four listed materials with two different thicknesses are compared for the specimen’s energy absorbed, specimen’s strain rate, stress strain rate relationship of the specimen, maximum energy absorbed, and maximum strain in specimen. It turned out that the dependency of deformation on energy absorption follows a power law for the woven composite and is approximated with linear relationships for aluminum and steel. Studying the effect of thickness in energy absorbed shows that doubling the thickness of the specimen reduces the strain of the specimen by 50 percentages for woven graphite epoxy and wood specimens, but the reduction is 25 percentages in the steel and aluminum specimens

Published
2012

31. The value of close monitoring in vestibular rehabilitation therapy.

Author

Itani, M, Koaik, Y, and Sabri, A

Subjects
*ACADEMIC medical centers, *COMPARATIVE studies, *VESTIBULAR apparatus diseases, *HOME environment, *TREATMENT effectiveness, *RETROSPECTIVE studies, *CLINICAL supervision, *DESCRIPTIVE statistics
Abstract

Background:Vestibular rehabilitation therapy is a well-established treatment modality for patients with vestibular problems.Hypothesis:Performing vestibular rehabilitation therapy in a closely monitored setting may result in a better outcome than a home exercise programme.Methods:A retrospective study was conducted of patients undergoing vestibular rehabilitation therapy between June 2005 and November 2012 in a tertiary university hospital. The Dynamic Gait Index, the main outcome measure, was utilised before and after the rehabilitation programme. The magnitude of improvement for all patients was analysed, mainly to compare the home exercise group with the closely monitored therapy group.Results:Only 32 patients underwent the vestibular rehabilitation therapy programme. In all patients, there was significant improvement in the mean Dynamic Gait Index score (from 11.75 to 17.38; p < 0.01). Dynamic Gait Index improvement was significantly higher with closely monitored therapy (mean improvement of 7.83 vs 2.79; p < 0.01).Conclusion:The small sample size is a major limitation; nevertheless, closely monitored vestibular rehabilitation therapy resulted in improved performance status. More studies are needed to establish the efficiency of vestibular rehabilitation therapy and compare closely monitored therapy with tailored home exercise rehabilitation. [ABSTRACT FROM AUTHOR]

Published
2017
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33. A Comparison of Pattern of Breathing during Incremental Exercise in Patients with Pulmonary Fibrosis and Primary Pulmonary Hypertension

Author

A. Al-Duhaim Ahmad, Abdullah Al-Shimemeri, Al-Moamary Mohamed, Alghadeer Hend, Al-Jahdali Hamdan, Mobeireek Abdullah, and Itani M

Subjects
medicine.medical_specialty, Lung, Respiratory rate, business.industry, Interstitial lung disease, General Medicine, medicine.disease, Pulmonary hypertension, Incremental exercise, medicine.anatomical_structure, Internal medicine, Pulmonary fibrosis, medicine, Breathing, Cardiology, business, Tidal volume
Abstract

It has previously been proposed that the pattern of breathing during exercise, and particularly maximum tidal volume, can be used to distinguish between interstitial lung disease and pulmonary vascular disease; however this has never been formally investigated. This study looks at the impact of incremental exercise on a bicycle ergometer and the impact that such exercise has on breathing pattern, specifically maximum tidal volume. Method: We retrospectively reviewed the incremental exercise tests of 10 patients with pulmonary fibrosis (PF) and 9 with primary pulmonary hypertension (PPH). Patients were exercised using a bicycle ergometer, seated, and breathing into a mouthpiece. Results: The VE/VCO2 relationship was linear in all patients, but PPH patients had higher VE/VCO2 slopes (0.058±0.03) mean ±SD than PF patients (0.039±0.01, P

Published
2013

36. The alpha 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy

Author

Knowlton, K. U., Michel, M. C., Itani, M., Shubeita, H. E., Ishihara, K., Brown, J. H., Chien, K. R., and Other departments

Abstract

alpha 1-Adrenergic agonists induce a hypertrophic phenotype in cultured neonatal rat ventricular myocytes. Quantifiable markers of this phenotype include stimulation of phosphoinositide hydrolysis, transcriptional induction of atrial natriuretic factor (ANF) gene expression, and an increase in myocardial cell size. The aim of the present work was to determine which alpha 1-adrenergic receptor subtype mediates the acquisition of these parameters of myocardial cell hypertrophy. Phosphoinositide hydrolysis is inhibited by low concentrations of 5-methylurapidil (log Ki = -8.7) and (+)-niguldipine (log Ki = -10.6). The alpha-adrenergic receptor-induced increase in transcriptional activation of an ANF luciferase reporter gene is inhibited over the same range of concentrations of 5-methylurapidil (log Ki = -8.2) and (+)-niguldipine (log Ki = -11.2) that inhibit phosphoinositide hydrolysis. In addition, the increase in cell size that accompanies alpha-adrenergic receptor stimulation of cultured ventricular myocytes is blocked by similar concentrations of 5-methylurapidil (log Ki = -8.0) and (+)-niguldipine (log Ki = -10.6). In contrast, treatment with the alpha 1B selective antagonist chlorethylclonidine at a concentration of 10 microM had no effect on the adrenergically mediated induction of ANF luciferase reporter gene expression or the adrenergically induced increase in myocardial cell size. These findings demonstrate that pharmacologically identifiable alpha 1A-adrenergic receptors mediate not only the early effects of alpha 1-adrenergic stimulation such as phosphoinositide hydrolysis, but that they activate the signaling pathways that control transcriptional induction of the ANF luciferase reporter gene and an increase in myocardial cell size. Studies using alpha 1-adrenergic receptor cDNAs to delineate and alter the direct interaction of this receptor subtype with proximal signaling molecules, e.g. GTP binding proteins, should provide a powerful means of assessing their role in the induction of the molecular and morphologic parameters of myocardial cell hypertrophy

Published
1993

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