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Juvenile nasopharyngeal angiofibroma (JNA) is the most common locally aggressive benign tumor of the nasopharynx, presenting with an incidence in male adolescents of up to 1:150,000. The main symptoms of JNA include epistaxis and progressive nasal obstruction. Its diagnosis is based on clinical and radiologic findings. Open or endoscopic surgery is the treatment of choice and its rate of recurrence ranges from 13% to 46%. Two 13-year-old male patients presented with a history of progressive nasal obstruction and recurrent epistaxis. CT and magnetic resonance imaging (MRI) revealed a tumorous lesion that extends from the pterygopalatine fossa to surrounding areas. They were diagnosed with JNA II-C (case 1) and III-B (case 2) according to Radkowski. Embolization and subsequent surgical resection was performed. After 2 years of follow-up, the patients remain asymptomatic without recurrence. The nature of the JNA makes its treatment a challenge, which must be approached in a multidisciplinary manner to achieve results with lower morbidity and mortality.

The glomus tumor (GT) is a benign neoplasm originating from the cells of the glomus body; its incidence in the head and neck region is 0.6%. Clinically, it presents as a small, soft, and solitary nodule with variable size and location. Histologically, it is classified into glomangioma, glomangiomyoma, and solid glomus tumor. Surgery is the treatment of choice and recurrence is rare. We present the case of a 29-year-old female patient, who presented with an exophytic lesion that was soft, painful, and bleeding, located at the level of the interdental papilla between the 11th and 21st teeth. The panoramic radiograph did not reveal relevant data and excisional biopsy was performed. The histopathologic report indicates glomangioma. Currently, after 1 year of follow-up, the patient remains asymptomatic with no recurrence. The intraoral GT are extremely rare, and their timely diagnosis will help reduce the morbidity associated with them.

The purpose of the present article was to present a clinical case of an 11-year-old girl with peripheral ossifying fibroma (POF). Additionally, after performing a literature review, we identified clinical information that occurs more frequently in association with POF, such evidence would help professionals in yielding a specific diagnosis and tailor a more specific therapeutic approach with the objective to decrease morbidities' associated with POF. This lesion represents the third most common lesion of all localized reactive hyperplastic lesions. Clinical aspects related to this pathology include the fact that it occurs most frequently in women between the first and second decades of life. It affects anterior maxillary region and interferes with normal functioning of this anatomical structure. After conducting the literature search, we found that it can also be presented in a considerable number of males with pain and hyperemia being the most common clinical manifestations. We found that often clinical cases are presented with incomplete information. It is important that in order to get to a consensus with respect to updates about information related to this lesion, new case series that include complete clinical information, radiographic analysis, and histopathology tests could be presented.