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The global shift from a fossil fuel-based to an electrical-based society is commonly viewed as an ecological improvement. However, the electrical power industry is a major source of carbon dioxide emissions, and incorporating renewable energy can still negatively impact the environment. Despite rising research in renewable energy, the impact of renewable energy consumption on the environment is poorly known. Here, we review the integration of renewable energies into the electricity sector from social, environmental, and economic perspectives. We found that implementing solar photovoltaic, battery storage, wind, hydropower, and bioenergy can provide 504,000 jobs in 2030 and 4.18 million jobs in 2050. For desalinization, photovoltaic/wind/battery storage systems supported by a diesel generator can reduce the cost of water production by 69% and adverse environmental effects by 90%, compared to full fossil fuel systems. The potential of carbon emission reduction increases with the percentage of renewable energy sources utilized. The photovoltaic/wind/hydroelectric system is the most effective in addressing climate change, producing a 2.11–5.46% increase in power generation and a 3.74–71.61% guarantee in share ratios. Compared to single energy systems, hybrid energy systems are more reliable and better equipped to withstand the impacts of climate change on the power supply.

New technologies, systems, societal organization and policies for energy saving are urgently needed in the context of accelerated climate change, the Ukraine conflict and the past coronavirus disease 2019 pandemic. For instance, concerns about market and policy responses that could lead to new lock-ins, such as investing in liquefied natural gas infrastructure and using all available fossil fuels to compensate for Russian gas supply cuts, may hinder decarbonization efforts. Here we review energy-saving solutions with a focus on the actual energy crisis, green alternatives to fossil fuel heating, energy saving in buildings and transportation, artificial intelligence for sustainable energy, and implications for the environment and society. Green alternatives include biomass boilers and stoves, hybrid heat pumps, geothermal heating, solar thermal systems, solar photovoltaics systems into electric boilers, compressed natural gas and hydrogen. We also detail case studies in Germany which is planning a 100% renewable energy switch by 2050 and developing the storage of compressed air in China, with emphasis on technical and economic aspects. The global energy consumption in 2020 was 30.01% for the industry, 26.18% for transport, and 22.08% for residential sectors. 10–40% of energy consumption can be reduced using renewable energy sources, passive design strategies, smart grid analytics, energy-efficient building systems, and intelligent energy monitoring. Electric vehicles offer the highest cost-per-kilometer reduction of 75% and the lowest energy loss of 33%, yet battery-related issues, cost, and weight are challenging. 5–30% of energy can be saved using automated and networked vehicles. Artificial intelligence shows a huge potential in energy saving by improving weather forecasting and machine maintenance and enabling connectivity across homes, workplaces, and transportation. For instance, 18.97–42.60% of energy consumption can be reduced in buildings through deep neural networking. In the electricity sector, artificial intelligence can automate power generation, distribution, and transmission operations, balance the grid without human intervention, enable lightning-speed trading and arbitrage decisions at scale, and eliminate the need for manual adjustments by end-users.

The development and recycling of biomass production can partly solve issues of energy, climate change, population growth, food and feed shortages, and environmental pollution. For instance, the use of seaweeds as feedstocks can reduce our reliance on fossil fuel resources, ensure the synthesis of cost-effective and eco-friendly products and biofuels, and develop sustainable biorefinery processes. Nonetheless, seaweeds use in several biorefineries is still in the infancy stage compared to terrestrial plants-based lignocellulosic biomass. Therefore, here we review seaweed biorefineries with focus on seaweed production, economical benefits, and seaweed use as feedstock for anaerobic digestion, biochar, bioplastics, crop health, food, livestock feed, pharmaceuticals and cosmetics. Globally, seaweeds could sequester between 61 and 268 megatonnes of carbon per year, with an average of 173 megatonnes. Nearly 90% of carbon is sequestered by exporting biomass to deep water, while the remaining 10% is buried in coastal sediments. 500 gigatonnes of seaweeds could replace nearly 40% of the current soy protein production. Seaweeds contain valuable bioactive molecules that could be applied as antimicrobial, antioxidant, antiviral, antifungal, anticancer, contraceptive, anti-inflammatory, anti-coagulants, and in other cosmetics and skincare products.

Cryptosporidium spp. is an obligate intracellular parasite that has become a community threat. The pathological consequences of cryptosporidiosis vary not only in different Cryptosporidium species but even among different isolates of the same species. The present study aimed to track the serological and immunohistopathological differences between animals infected by Cryptosporidium parvum "Iowa isolate" (CPI) and Cryptosporidium parvum "water isolate" isolated from a local water supply in Assiut Governorate, Egypt (CPW). Three experimental groups were encountered: negative control group (C), the CPI group and the CPW group; each contains ten Swiss albino mice. Serum cytokine: IL10 and TNF-α were measured. Expression of Cryptosporidium antigen and CD3 in the intestinal, pulmonary and brain tissue were evaluated through immunohistochemical assay. IL10 and TNF-α were elevated in both infected groups, over expression of Cryptosporidium protein and CD3 in the intestinal, pulmonary and brain tissue in CPW infected group compared to Iowa infected one. Multi-organs affection occurred in the CPW indicating more severe pathogenicity and virulence than standard Iowa isolate. The local C. parvum isolate was more virulent than tested Iowa isolate as it spread extra-intestinally to reach brain tissue.