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21 results on '"Ismail, Sophia Rasheeqa"'

1. The effects of school-based hygiene intervention programme: Systematic review and meta-analysis.

Author

Ismail, Sophia Rasheeqa, Radzi, Ranina, Megat Kamaruddin, Puteri Sofia Nadira, Lokman, Ezarul Faradianna, Lim, Han Yin, Abdul Rahim, Nusaibah, Yow, Hui Yin, Arumugam, Daarshini, Ngu, Alex, Low, Annie Ching Yi, Wong, Eng Hwa, Patil, Sapna, Madhavan, Priya, Nordin, Ruslin Bin, van der Werf, Esther, and Lai, Nai Ming

Subjects
*ORAL hygiene, *DENTAL hygiene, *CLINICAL trials, *SCHOOL attendance, *DENTAL caries, *HAND washing
Abstract

Children are susceptible to infections due to frequent participation in school group activities and their often-suboptimal hygiene practices. Frequent infections in children affect school attendance, academic performances, and general health. The effectiveness of school-based hygiene-related intervention programmes need to be informed by updated high-quality synthesised evidence. In this systematic review, we searched PubMed and Cochrane CENTRAL for randomised and non-randomised interventional studies that evaluated school-based hygiene-related interventions. We assessed risk-of-bias (Cochrane risk-of-bias 2 tool), performed random-effect meta-analysis (RevMan 5.4) and rated certainty-of-evidence (GRADE). Thirty-nine trials (41 reports), published from 2011 to 2024 from 22 countries were included. Twenty-three studies contributed data for meta-analysis. All school-based interventions were compared with standard curriculum and demonstrated very low to low certainty-of-evidence due to study methodological limitations and imprecision. Hand-body hygiene interventions may improve knowledge, attitudes and practices (SMD 2.30, 95%CI 1.17 to 3.44, 6 studies, 7301 participants), increase handwashing practices (RR 1.75, 95%CI 1.41 to 2.17, 5 studies, 5479 participants), and reduce infection-related absenteeism (RR 0.74, 95%CI 0.66 to 0.83, 5 studies, 1017852 observations). Genital hygiene interventions may improve attitude (SMD 6.53, 95%CI 2.40 to 10.66, 2 studies, 2644 participants) and practices (RR 2.44, 95%CI 1.28 to 4.68, 1 study, 1201 participants). However, intervention effects on oral hygiene appeared mixed, with worsening of the oral hygiene score (SMD 3.12, 95%CI 1.87 to 4.37, 2 studies, 652 participants) but improved dental hygiene (SMD -0.33, 95%CI -0.53 to -0.13, 3 studies, 4824 participants) and dental caries scores (SMD -0.34, 95%CI -0.52 to -0.16, 4 studies, 2352 participants). Limited evidence suggests that interventions targeting hand-body and genital hygiene practices may improve knowledge, practices, and infection-related absenteeism. However, the effects on oral hygiene intervention appeared mixed. Future research should strengthen randomisation and intervention documentation, and evaluate hygiene-related behaviour, academic performances and health outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Risk Factors of Secondary Cardiovascular Events in a Multi-Ethnic Asian Population with Acute Myocardial Infarction: A Retrospective Cohort Study from Malaysia

Author

Ismail, Sophia Rasheeqa, Mohammad, Mohd Shawal Faizal, Butterworth, Adam S, Chowdhury, Rajiv, Danesh, John, Di Angelantonio, Emanuele, Griffin, Simon J, Pennells, Lisa, Wood, Angela M, Md Noh, Mohd Fairulnizal, Shah, Shamsul Azhar, Ismail, Sophia Rasheeqa [0000-0002-4271-0241], Chowdhury, Rajiv [0000-0003-4881-5690], Shah, Shamsul Azhar [0000-0003-0635-1816], and Apollo - University of Cambridge Repository

Subjects
myocardial infarction, Asian, cardiovascular mortality, risk factors, major adverse cardiovascular events
Abstract

This retrospective cohort study investigated the incidence and risk factors of major adverse cardiovascular events (MACE) after 1 year of first-documented myocardial infarctions (MIs) in a multi-ethnic Asian population. Secondary MACE were observed in 231 (14.3%) individuals, including 92 (5.7%) cardiovascular-related deaths. Both histories of hypertension and diabetes were associated with secondary MACE after adjustment for age, sex, and ethnicity (HR 1.60 [95%CI 1.22-2.12] and 1.46 [95%CI 1.09-1.97], respectively). With further adjustments for traditional risk factors, individuals with conduction disturbances demonstrated higher risks of MACE: new left-bundle branch block (HR 2.86 [95%CI 1.15-6.55]), right-bundle branch block (HR 2.09 [95%CI 1.02-4.29]), and second-degree heart block (HR 2.45 [95%CI 0.59-10.16]). These associations were broadly similar across different age, sex, and ethnicity groups, although somewhat greater for history of hypertension and BMI among women versus men, for HbA1c control in individuals aged >50 years, and for LVEF ≤ 40% in those with Indian versus Chinese or Bumiputera ethnicities. Several traditional and cardiac risk factors are associated with a higher risk of secondary major adverse cardiovascular events. In addition to hypertension and diabetes, the identification of conduction disturbances in individuals with first-onset MI may be useful for the risk stratification of high-risk individuals.

Published
2023

4. Risk Factors of Secondary Cardiovascular Events in a Multi-Ethnic Asian Population with Acute Myocardial Infarction: A Retrospective Cohort Study from Malaysia

Author

Ismail, Sophia Rasheeqa, primary, Mohammad, Mohd Shawal Faizal, additional, Butterworth, Adam S., additional, Chowdhury, Rajiv, additional, Danesh, John, additional, Di Angelantonio, Emanuele, additional, Griffin, Simon J., additional, Pennells, Lisa, additional, Wood, Angela M., additional, Md Noh, Mohd Fairulnizal, additional, and Shah, Shamsul Azhar, additional

Published
2023
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7. Investigating Genetic and Other Determinants of First-Onset Myocardial Infarction in Malaysia: Protocol for the Malaysian Acute Vascular Events Risk Study (Preprint)

Author

Chowdhury, Rajiv, primary, Noh, Mohd Fairulnizal Md, additional, Ismail, Sophia Rasheeqa, additional, van Daalen, Kim Robin, additional, Kamaruddin, Puteri Sofia Nadira Megat, additional, Zulkiply, Siti Hafizah, additional, Azizul, Nur Hayati, additional, Khalid, Norhayati Mustafa, additional, Ali, Azizan, additional, Idris, Izyan Mohd, additional, Mei, Yong Shih, additional, Abdullah, Shazana Rifham, additional, Faridus, Norfashihah, additional, Yusof, Nur Azirah Md, additional, Yusoff, Nur Najwa Farahin M, additional, Jamal, Rahman, additional, Rahim, Aizai Azan Abdul, additional, Ghapar, Abdul Kahar Abdul, additional, Radhakrishnan, Ammu Kutty, additional, Fong, Alan Yean Yip, additional, Ismail, Omar, additional, Krishinan, Saravanan, additional, Lee, Chuey Yan, additional, Bang, Liew Houng, additional, Mageswaren, Eashwary, additional, Mahendran, Kauthaman, additional, Amin, Nor Hanim Mohd, additional, Muthusamy, Gunavathy, additional, Jin, Aaron Ong Hean, additional, Ramli, Ahmad Wazi, additional, Ross, Noel Thomas, additional, Ruhani, Anwar Irawan, additional, Yahya, Mansor, additional, Yusoff, Yusniza, additional, Abidin, Siti Khairani Zainal, additional, Amado, Laryssa, additional, Bolton, Thomas, additional, Weston, Sophie, additional, Crawte, Jason, additional, Ovenden, Niko, additional, Michielsen, Ank, additional, Monower, Md Mostafa, additional, Mahiyuddin, Wan Rozita Wan, additional, Wood, Angela, additional, Di Angelantonio, Emanuele, additional, Sulaiman, Nur Suffia, additional, Danesh, John, additional, and Butterworth, Adam S, additional

Published
2021
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8. The Malaysian Acute Vascular Events Risk (MAVERIK) study protocol: studying genetic and other determinants of first-ever myocardial infarction in Malaysia (Preprint)

Author

Chowdhury, Rajiv, primary, Noh, Mohd Fairulnizal Bin Md, additional, Ismail, Sophia Rasheeqa, additional, van Daalen, Kim Robin, additional, Kamaruddin, Puteri Sofia Nadira Megat, additional, Zulkiply, Siti Hafizah, additional, Azizul, Nur Hayati, additional, Khalid, Norhayati Mustafa, additional, Ali, Azizan, additional, Idris, Izyan Mohd, additional, Mei, Yong Shih, additional, Abdullah, Shazana Rifham, additional, Faridus, Norfashihah, additional, Yusof, Nur Azirah Md, additional, Yusoff, Nur Najwa Farahin M, additional, Jamal, Rahman, additional, Rahim, Aizai Azan Abdul, additional, Radhakrishnan, Ammu Kutty, additional, Ghapar, Abdul Kahar Abdul, additional, Fong, Alan Yean Yip, additional, Ismail, Omar, additional, Krishinan, Saravanan, additional, Yan, Lee Chuey, additional, Bang, Liew Houng, additional, Mageswaren, Eashwary, additional, Mahendran, Kauthaman, additional, Amin, Nor Hanim Mohd, additional, Muthusamy, Gunavathy, additional, Jin, Aaron Ong Hean, additional, Ramli, Ahmad Wazi, additional, Ross, Noel Thomas, additional, Ruhani, Anwar Irawan, additional, Yahya, Mansor, additional, Yusoff, Yusniza, additional, Abidin, Siti Khairani Zainal, additional, Amado, Laryssa, additional, Bolton, Thomas, additional, Weston, Sophie, additional, Crawte, Jason, additional, Ovenden, Niko, additional, Michielsen, Ank, additional, Monower, Md Mostafa, additional, Mahiyuddin, Wan Rozita Wan, additional, Wood, Angela, additional, Di Angelantonio, Emanuele, additional, Sulaiman, Nur Suffia, additional, Danesh, John, additional, and Butterworth, Adam S., additional

Published
2021
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18. Investigating Genetic and Other Determinants of First-Onset Myocardial Infarction in Malaysia: Protocol for the Malaysian Acute Vascular Events Risk Study.

Author

Chowdhury, Rajiv, Noh, Mohd Fairulnizal Md, Ismail, Sophia Rasheeqa, van Daalen, Kim Robin, Kamaruddin, Puteri Sofia Nadira Megat, Zulkiply, Hafizah, Azizul, Nur Hayati, Khalid, Norhayati Mustafa, Ali, Azizan, Idris, Izyan Mohd, Mei, Yong Shih, Abdullah, Shazana Rifham, Faridus, Norfashihah, Yusof, Nur Azirah Md, Yusoff, Nur Najwa Farahin M., Jamal, Rahman, Rahim, Aizai Azan Abdul, Ghapar, Abdul Kahar Abdul, Radhakrishnan, Ammu Kutty, and Fong, Alan Yean Yip

Subjects
MYOCARDIAL infarction, PUBLIC health, CARDIOVASCULAR diseases, MEDICAL care
Abstract

Background: Although the burden of premature myocardial infarction (MI) is high in Malaysia, direct evidence on the determinants of MI in this multi-ethnic population remains sparse. Objective: The Malaysian Acute Vascular Events Risk (MAVERIK) study is a retrospective case-control study established to investigate the genomic, lipid-related, and other determinants of acute MI in Malaysia. In this paper, we report the study protocol and early results. Methods: By June 2019, we had enrolled approximately 2500 patients with their first MI and 2500 controls without cardiovascular disease, who were frequency-matched by age, sex, and ethnicity, from 17 hospitals in Malaysia. For each participant, serum and whole blood have been collected and stored. Clinical, demographic, and behavioral information has been obtained using a 200-item questionnaire. Results: Tobacco consumption, a history of diabetes, hypertension, markers of visceral adiposity, indicators of lower socioeconomic status, and a family history of coronary disease were more prevalent in cases than in controls. Adjusted (age and sex) logistic regression models for traditional risk factors indicated that current smoking (odds ratio [OR] 4.11, 95% CI 3.56-4.75; P<.001), previous smoking (OR 1.34, 95% CI 1.12-1.60; P=.001), a history of high blood pressure (OR 2.13, 95% CI 1.86-2.44; P<.001), a history of diabetes mellitus (OR 2.72, 95% CI 2.34-3.17; P<.001), a family history of coronary heart disease (OR 1.28, 95% CI 1.07-1.55; P=.009), and obesity (BMI >30 kg/m2; OR 1.19, 95% CI 1.05-1.34; P=.009) were associated with MI in age- and sex-adjusted models. Conclusions: The MAVERIK study can serve as a useful platform to investigate genetic and other risk factors for MI in an understudied Southeast Asian population. It should help to hasten the discovery of disease-causing pathways and inform regionally appropriate strategies that optimize public health action. [ABSTRACT FROM AUTHOR]

Published
2022
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21. The Malaysian Acute Vascular Events Risk (MAVERIK) study protocol: studying genetic and other determinants of first-ever myocardial infarction in Malaysia (Preprint)

Author

Chowdhury, Rajiv, Noh, Mohd Fairulnizal Bin Md, Ismail, Sophia Rasheeqa, Van Daalen, Kim Robin, Kamaruddin, Puteri Sofia Nadira Megat, Zulkiply, Siti Hafizah, Azizul, Nur Hayati, Khalid, Norhayati Mustafa, Ali, Azizan, Idris, Izyan Mohd, Mei, Yong Shih, Abdullah, Shazana Rifham, Faridus, Norfashihah, Yusof, Nur Azirah Md, Yusoff, Nur Najwa Farahin M, Jamal, Rahman, Rahim, Aizai Azan Abdul, Radhakrishnan, Ammu Kutty, Ghapar, Abdul Kahar Abdul, Fong, Alan Yean Yip, Ismail, Omar, Krishinan, Saravanan, Yan, Lee Chuey, Bang, Liew Houng, Mageswaren, Eashwary, Mahendran, Kauthaman, Amin, Nor Hanim Mohd, Muthusamy, Gunavathy, Jin, Aaron Ong Hean, Ramli, Ahmad Wazi, Ross, Noel Thomas, Ruhani, Anwar Irawan, Yahya, Mansor, Yusoff, Yusniza, Abidin, Siti Khairani Zainal, Amado, Laryssa, Bolton, Thomas, Weston, Sophie, Crawte, Jason, Ovenden, Niko, Michielsen, Ank, Monower, Md Mostafa, Mahiyuddin, Wan Rozita Wan, Wood, Angela, Di Angelantonio, Emanuele, Sulaiman, Nur Suffia, Danesh, John, Butterworth, Adam S, Wood, Angela [0000-0002-7937-304X], Di Angelantonio, Emanuele [0000-0001-8776-6719], Danesh, John [0000-0003-1158-6791], Butterworth, Adam [0000-0002-6915-9015], and Apollo - University of Cambridge Repository

Abstract

INTRODUCTION: Although the burden of premature myocardial infarction (MI) is high in Malaysia, direct evidence on the determinants of MI in this multi-ethnic population remains sparse. The Malaysian Acute Vascular Events Risk (MAVERIK) study is a retrospective case-control study established to enable investigation of genomic, lipid-related and other determinants of acute MI in Malaysia. To our knowledge, it represents the largest case-control study of MI and related traits in Malaysia. In this paper, we report the study’s design and initial results. METHODS: By June 2019, MAVERIK had enrolled about 2500 patients with first-ever MI and 2500 controls without cardiovascular disease (CVD), frequency-matched by age, sex and ethnicity, from 17 hospitals in Malaysia. For each participant, serum and whole blood have been collected and stored. Clinical, demographic and behavioural information has been obtained using a 200-item questionnaire. RESULTS: Tobacco consumption, history of diabetes, hypertension, markers of visceral adiposity, indicators of lower socioeconomic status, and family history of coronary disease were more prevalent in cases than controls. Crude and adjusted (age, sex) logistic regression models for traditional risk factors indicated that current smoking, previous smoking, history of high blood pressure, history of diabetes mellitus, family history of CHD and obesity (BMI>30) were associated with MI in age- and sex-adjusted models. CONCLUSION: The MAVERIK study can serve as a useful platform to investigate genetic and other risk factors for MI in an under-studied South-East Asian population. It should help to hasten discovery of disease-causing pathways and to inform regionally appropriate strategies that optimise public health action.

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