977 results on '"Ismail, O. A."'
Search Results
2. Dynamics of extreme spillovers across European sustainability markets
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Mensi, Walid, Fasanya, Ismail O., Vo, Xuan Vinh, and Kang, Sang Hoon
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- 2024
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3. Critical appraisal of Monkeypox (Mpox) in Africa using scoping and systematic review methods
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Abdul-Azeez A. Anjorin, Ismail A. Odetokun, Oluwaseyi S. Ashaka, Temitope O. Fadipe, Aliyu Muhammed, Jean B. Nyandwi, Oyewale M. Morakinyo, Akeem B. Dauda, Mutiat A. Adetona, Sodiq O. Tijani, Wasiu O. Salami, Murtala B. Isah, George Gachara, Abdulazeez O. Giwa, Mohammed Lounis, Aala M. Maisara, Ezekiel F. Hallie, Ismail O. Adesanya, Rasha Mosbah, Kingsley N Ukwaja, and Mohammed A. Ibrahim
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monkey pox virus ,africa ,epidemiology ,one health ,Science - Abstract
Africa remains a battlefield for the emergence and re-emergence of deadly aetiologies including the Lassa fever virus from 1969, Monkey pox (mpox) virus from 1970, and Ebola virus from 1976 till date, among others. With the recent index case of mpox following rapid spread from Africa to different continents, a critical appraisal of the disease to x-ray its dynamics in Africa is warranted. This study integrated a mix of scoping and systematic reviews to converse the epidemiology and biosecurity/environmental issues from one health perspective. Our scoping review used major scientific databases based on their relevance and reliability, while the PROSPERO-registered systematic review followed the PRISMA guidelines. Phylogeny analysis was performed to compare recent outbreaks of mpox with the existing genotypic information. The genetic analysis focused on the H3L gene that codes for envelope proteins involved in viral attachment. Transmission of mpox virus was reported mainly in four routes. Animals implicated include monkeys, squirrels, and pigs. Risk factors include age, gender, occupation, climate, travel, political instability, and vaccination status. Different circulating strains were reported with eight-point mutations found to occur in Africa. Observed clustering within the predominant West African (WA) clade and the recent outbreak strains corroborate the reports of WA clade in other non-African and non-endemic countries. Viral adaptation in the WA clade enhanced person-to-person transmissibility, spreading to over 100 countries. Hence, there is need to address Mpox host-associated physiological and biochemical changes, the development of Mpox virus-specific diagnostic kits and vaccines, and studies on the disease's socio-ecological, economic and psychological consequences.
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- 2024
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4. Do fintech, natural resources and globalization matter during ecological crises? A step towards ecological sustainability
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Kingsley I. Okere, Stephen Kelechi Dimnwobi, and Ismail O. Fasanya
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Environmental sustainability ,FinTech ,Natural resources ,Globalization ,North Africa ,Management. Industrial management ,HD28-70 ,Business ,HF5001-6182 - Abstract
The rate of biodiversity loss and forest depletion has surged significantly, primarily driven by the substantial increase in worldwide environmental deterioration. This alarming development is nearing the critical temperature limit of 2 °C, necessitating increased scrutiny. This study therefore adopts the Load Capacity Curve framework that amalgamates these concepts, offering a guide for implementing a robust and sustainable adaptation plan in the North African region. The research utilized data spanning from 1991 to 2022 and employed advanced quantitative methods, including quantile regression (QR), augmented mean group (AMG), and the Half-Panel Jackknife (HPJ) Wald-type test, to explore causality. The empirical findings challenge the notion of a U-shaped relationship between per capita GDP and ecological load capacity, revealing instead an inverted U-shaped pattern at the 25th and 50th quantiles. Additionally, the study identifies a negative and significant association between natural resource rents and globalization with the ecological load capacity factor, indicating a detrimental effect. On the other hand, Fintech demonstrates a statistically significant and positive impact on environmental sustainability, indicating a mitigating effect. Causality tests further reveal bidirectional causality between ecological load capacity and per capita GDP, GDP squared, and Fintech, while a unidirectional positive relationship exists between globalization and ecological load capacity. Based on these findings, the study puts forth several policy recommendations to support informed decision-making.
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- 2024
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5. Single-crystal X-ray, spectroscopy, quantum chemical calculations, and molecular docking investigation of ruthenium (II) polypyridyl complexes of curcumin as a potential chemotherapy drug in the treatment of malignant glioblastoma (GBM)
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Rajee, Abdullahi O., Obaleye, Joshua A., Louis, Hitler, Aliyu, Abdulbasit A., Lawal, Amudat, Amodu, Ismail O., Timothy, Rawlings A., Ayinla, Sheriff O., Adesope, Kareemat T., and Manicum, Amanda-Lee E.
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- 2024
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6. A protocol for the study of environmental risk factors and candidate gene–environment interactions in neurodegenerative disorders in Nigeria (SERGEND): A cross-sectional descriptive study
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Oluwadamilola Omolara Ojo, Osigwe P Agabi, Ismail O Ishola, Olajumoke O Oshinaike, Sani A Abubakar, Kolawole W Wahab, Abiodun H Bello, Rufus O Akinyemi, Uduak Williams, Simon I Ozomma, Oluchi Ekenze, Emmanuel Iwuozo, Yakub W Nyandaiti, Francis I Ojini, Henry Houlden, John Hardy, and Njideka Ulunma Okubadejo
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africa ,apoe ,dementia ,environmental risk ,genetics ,nigeria ,parkinsonism ,snca ,Medicine (General) ,R5-920 - Abstract
Introduction: The risk of developing neurodegenerative disorders (NDDs) such as Alzheimer’s disease and related dementias (ADRD) and Parkinson’s disease and atypical parkinsonism (PDAP), has been alluded to arise predominantly from the interplay between environmental exposures and genetic variability. The contributions of these factors to NDD in Black sub-Saharan Africans are largely unknown. The broad aim of SERGEND is to investigate the effect of specific environmental exposures and genetic variability on the risk of developing ADRD and PDAP in our population. Methods: The SERGEND, a national, multi-center, cross-sectional, descriptive study, will be conducted in Nigeria, within academic hospitals located in all six geopolitical zones of the country. The study population will comprise 3000 consenting adult Nigerians aged 18 years and above, residing within the recruiting geopolitical zone in the preceding 12 months. Cases will be persons with ADRD or PDAP and age-matched healthy controls. Assessments will include dementia and parkinsonism-specific case ascertainment, disease severity, functional status, and environmental risk factors assessment. Genotyping for APOE and SNCA REP1 polymorphic variability will be conducted. Future analyses will be performed on biobanked samples. Ethics and Dissemination: The study protocol was approved by the National Health Research Ethics Committee in Nigeria, with institutional HREC concordant approval for all participating sites before enrollment of the study participants. Written informed consent was obtained from all study participants or identified proxies. The study results will be published in peer-reviewed journals and as conference abstracts. Trial Registration: International Standard Registered Clinical/soCial sTudy Number (ISRCTN) registry (www.isrctn.com). Trial registration number: ISRCTN10548575. Locator ID: https://doi.org/10.1186/ISRCTN10548575
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- 2024
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7. Demographic and clinical correlates of depression among older adults with arthritis in Nigeria
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Yesiru A. Kareem, Placidus N. Ogualili, Kehinde A. Alatishe, Ismail O. Adesina, Fatima A. Ali, Taiwo A. Alatishe, and Richard Uwakwe
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demographic ,clinical ,correlates ,depression ,older adults ,Psychiatry ,RC435-571 - Abstract
Background: Older adults have a high prevalence of chronic conditions like arthritis with morbidities, especially depression ranging up to 40% – 70%. Therefore, it is important to explore depression in older adults with arthritis. Aim: This study aimed to determine if any demographic and clinical factors are associated with depression in older adults aged ≥ 60 years with arthritis attending a rheumatology clinic. Setting: This is a cross-sectional study conducted over 6 months among 127 older adults on follow-up care in a university teaching hospital in the North-Eastern region of Nigeria. Methods: A clinical proforma with information about the type of arthritis, duration of illness, hospitalisation, use of medications, co-morbidity was utilised for the data collection. The Geriatric Depression Scale (GDS-30), sociodemographic questionnaire and clinical proforma were administered. Data were analysed using Statistical Product and Service Solutions (SPSS) version 26.0 with the level of significance set as 0.05. Results: The mean age (± standard deviation [s.d.]) was 66.6 (± 5.5) years, with males constituting 57.5%. The prevalence of depression was 57.8%. Osteoarthritis 30.2%, while 69.8% had rheumatoid arthritis. Sociodemographic factors associated with depression include age (p = 0.049), marital status (p = 0.001), and level of education (p = 0.001). Duration of illness (p = 0.02), hospitalisation (p = 0.03), and number of medications (p = 0.01) were clinical factors associated with depression score. Conclusion: The prevalence of depression in older people with arthritis is high and was associated with females, the widowed, no formal education; and those with long duration of illness, those using multiple medications, and those with repeated hospitalisation. Contribution: This finding can enhance the suspicion index for depression to establish standard operating procedures, which will help to improve therapeutic practice for caring for the older adult age group.
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- 2024
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8. Do fintech, natural resources and globalization matter during ecological crises? A step towards ecological sustainability
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Okere, Kingsley I., Dimnwobi, Stephen Kelechi, and Fasanya, Ismail O.
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- 2024
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9. Utilizing Mitracarpus scaber extracts for green synthesis of silver nanoparticles: Exploring physicochemical properties and potential chemopreventive activity against N-methyl-nitrosourea- induced prostate carcinoma in rats
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Adesipe, Temitayo I., Iweala, Emeka J., Ishola, Ismail O., Arotiba, Omotayo A., and Adebayo, Abiodun H.
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- 2024
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10. Suicidal behaviour among patients with congestive cardiac failure in a Nigerian teaching hospital
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Tomilola O. Shofu-Akanji, Bolanle A. Ola, Dapo A. Adegbaju, Adeola O. Ajibare, Adefemi A. Adeoye, and Ismail O. Adesina
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congestive cardiac failure ,heart failure ,suicidal behaviour ,suicidal ideation ,suicidal attempt ,sociodemographic factors ,clinical factors ,Psychiatry ,RC435-571 - Abstract
Background: Suicidal behaviour is an established psychiatric complication of congestive cardiac failure (CCF), contributing significantly to morbidity and death by suicide. The magnitude and risk factors for suicidal behaviour among patients with CCF are yet to be unpacked, especially in developing nations such as Nigeria. Aim: To determine the prevalence of suicidal behaviour and the risk factors associated with suicidal behaviour, among patients with CCF in Nigeria. Setting: Cardiology outpatient clinic of Lagos State University Teaching Hospital, Lagos, Nigeria. Methods: A cross-sectional study was conducted among 98 randomly selected patients with a diagnosis of CCF. Participants were assessed with a socio-demographic and clinical factors questionnaire and Beck Scale of Suicidal Ideation. Chi-square test, t-test and logistic regression were used to analyse data. Results: The prevalence of suicidal ideation and suicidal attempt among patients with CCF was 52% and 1%, respectively. No socio-demographic factor was significantly associated with suicidal ideation. Clinical factors associated with suicidal ideation were age at diagnosis (p = 0.042), aetiology of CCF (p = 0.001) and severity of CCF (p = 0.032). Only the severity of CCF (odds ratio [OR] = 20.557, p = 0.014) predicted suicidal ideation among patients with CCF. Conclusion: Suicidal behaviour constitutes a huge burden among the outpatient CCF population. The identification of clinical risk factors for suicidal ideation (age at diagnosis, aetiology and severity of CCF) further illuminates a pathway to mortality among patients with CCF. Contribution: The findings lend a voice to the need for screening for suicidal behaviour, suicide prevention programmes, surveillance systems and government policies that support mental health for patients with CCF.
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- 2024
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11. Modeling the Interactionof F-gases on Ruthenium-Doped Boron Nitridenanotube
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Louis, Hitler, Amodu, Ismail O., Eno, Ededet A., Benjamin, Innocent, Gber, Terkumbur E., Unimuke, Tomsmith O., Isang, Bartholomew B., and Adeyinka, Adedapo S.
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- 2023
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12. Glimepiride Prevents 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Induced Dopamine Neurons Degeneration Through Attenuation of Glia Activation and Oxidative Stress in Mice
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Oduola-Akande, Mariam D., Ishola, Ismail O., Olubodun-Obadun, Taiwo G., Akande, Adeola J., and Adeyemi, Olufunmilayo O.
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- 2023
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13. Cajanus cajan (L) Millsp seeds extract prevents rotenone-induced motor- and non-motor features of Parkinson disease in mice: Insight into mechanisms of neuroprotection
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Olubodun-Obadun, Taiwo G., Ishola, Ismail O., Folarin, Oluwabusayo R., Oladoja, Farouk A., Gilbert, Taidinda T., Aniekwensi, Ifunanya M., Bisiriyu, Afolabi, Joseph-Iwebi, Nkem A., Adebanjo, Foluke O., Olopade, James O., and Adeyemi, Olufunmilayo O.
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- 2024
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14. Mn-doped covalent organic framework (COF), graphene, and their nanocomposite (Mn@GP/COF) as sensors for oil-dissolved gases in transformer: A computational study
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Amodu, Ismail O., Raimi, Monsurat, Ogbogu, Miracle N., Benjamin, Innocent, Gulack, Alpha O., Adeyinka, Adedapo S., and Louis, Hitler
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- 2024
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15. Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial
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Faust, Saul N, Haynes, Richard, Jones, Christine E, Staplin, Natalie, Whittaker, Elizabeth, Jaki, Thomas, Juszczak, Ed, Spata, Enti, Wan, Mandy, Bamford, Alasdair, Dimitri, Paul, Finn, Adam, Furness, John, Ramanan, Athimalaipet V, Gale, Christopher, Cathie, Katrina, Drysdale, Simon, Bernatoniene, Jolanta, Murray, Clare, Roehr, Charles C, Fleming, Paul, Riordan, Andrew, Bandi, Srini, Jyothish, Deepthi, Evans, Jennifer, Emonts, Marieke, Kelly, Dominic, Pathan, Nazima, Davies, Patrick, Hague, Rosie, Pollock, Louisa, Semple, Malcolm G, Peto, Leon, Baillie, J Kenneth, Buch, Maya, Jeffery, Katie, Knight, Marian, Lim, Wei Shen, Montgomery, Alan, Mukherjee, Aparna, Mumford, Andrew, Rowan, Kathryn, Thwaites, Guy, Mafham, Marion, Emberson, Jonathan, Landray, Martin J, Horby, Peter W, Chappell, Lucy, Day, Jeremy, Dung, DV, Quang, NN, Binh, Prof, Burhan, E, Alisjahbana, B, Koirala, J, Basnet, S, Kestelyn, E, Basnyat, B, Gyanwali, P, Hamers, RL, Sandercock, P, Darbyshire, J, DeMets, D, Fowler, R, Lalloo, D, Munavvar, M, Roberts, I, Warris, A, Wittes, J, Craddock-Bamford, A, Barton, J, Basoglu, A, Brown, R, Brudlo, W, Denis, E, Fletcher, L, Howard, S, Musini, S, Taylor, K, Cui, G, Goodenough, B, King, A, Lay, M, Murray, D, Stevens, W, Wallendszus, K, Welsh, R, Crichton, C, Davies, J, Goldacre, R, Harper, C, Knight, F, Nunn, M, Salih, H, Welch, J, Campbell, M, Pessoa-Amorim, G, Zayed, M, Wiles, J, Bagley, G, Cameron, S, Chamberlain, S, Farrell, B, Freeman, H, Kennedy, A, Whitehouse, A, Wilkinson, S, Wood, C, Reith, C, Davies, K, Halls, H, Holland, L, Truell, R, Wilson, K, Lingwood, Emma, Howie, L, Lunn, M, Rodgers, Penelope, Amuasi, J, Baird, K, Bao, T, Bittaye, M, Bonney, J, D'Alessandro, U, Dhimal, M, Huyen, T, Jagne, A, Karkey, A, Maiga, O, Matey, E, Nadjm, B, Nel, J, Pant, S, Puspatriani, K, Rahardjani, M, Raijal, S, Rees, H, Rimainar, A, Roberts, C, Rocca, A, Shrestha, S, Usuf, E, Vidaillic, C, Wulandari, F, Alexander, A, Amezaga, M, Armah, C, Asghar, A, Aubrey, P, Barker-Williams, K, Barnard, A, Bartholomew, J, Beaumont-Jewell, D, Beddows, S, Beety, J, Birch, C, Boyle, P, Brend, M, Brookes, M, Callens, C, Campbell, D, Campbell, H, Cate, H, Chambers, E, Chapman, K, Coe, A, Collins, J, Crawshaw, S, Das, S, De Soyza, A, Denton, E, Dicks, P, Dolman, M, Donaldson, K, Dowden, L, Dowling, S, Drake, C, Duckles-Leech, H, Duffy, H, Gerdes, L, Gibbons, K, Gill, L, Gilmour, K, Goodwin, J, Graham, J, Green, C, Hall, C, Hall, A, Hampshire, K, Hanson, J, Harman, T, Harper, H, Harrison, S, Hicks, J, Hodgson, H, Hough, M, Jackson, S, Johnson, G, Kirk, J, Lemoine, N, Levett, C, Lock, S, Lockett, T, Logan, M, Lomme, K, Luo, J, McMillan, N, Membrey, H, Mguni, N, Minton, J, Monaghan, H, Murphy, S, Muzengi, N, Naz, M, Nickson, I, Odam, M, Ohia, U, Okell, E, Oliver, A, Pearson, K, Pine, K, Pleass, R, Porter, D, Porter, L, Potter, A, Poustie, V, Pratt, S, Price, A, Priest, A, Rodgers, A, Rook, C, Ryan, P, Sam, S, Sharratt, P, Sheffield, J, Shenton, J, Shirley, K, Skinner, T, Slade, H, Sutu, M, Taylor, J, Thomas, E, Tinkler, H, Unsworth, A, Usher, R, van't Hoff, W, Walker, S, Walters, J, Walton, E, Warmington, J, Wayman, E, Williams, P, Williamson, J, Williamson, D, Yelnoorkar, F, Knight, M, Hodson, K, Pavord, S, Williamson, C, Bowman, L, Chen, F, Clarke, R, Goonasekara, M, Herrington, W, Judge, P, Ng, S, Preiss, D, Sammons, E, Zhu, D, Arkley, C, Bowker, P, Bruce, J, Byrne-Watts, V, Chapman, G, Coleman, G, Denwood, T, Gray, J, Harrison, D, Mather, N, Pinches, H, Rees, A, Rees, S, Turner, G, Abani, O, Abbas, A, Abbas, F, Abbas, J, Abbas, K, Abbas, M, Abbasi, S, Abbass, H, Abbott, A, Abdallah, N, Abdelaziz, A, Abdelfattah, M, Abdelqader, B, Abdul, A, Abdul, B, Abdul, S, Abdul Rasheed, A, Abdulakeem, A, Abdul-Kadir, R, Abdullah, A, Abdulmumeen, A, Abdul-Raheem, R, Abdulshukkoor, N, Abdusamad, K, Abed El Khaleq, Y, Abedalla, M, Abeer Ul Amna, A, Abel, L, Abernethy, K, Abeywickrema, M, Abhinaya, C, Aboaba, A, Aboagye-Odei, A, Aboelela, H, Abo-Leyah, H, Abouelela, K, Abou-Haggar, A, Abouibrahim, M, Abousamra, A, Abouzaid, M, Abraham, M, Abraham, T, Abraheem, A, Abrams, J, Abrams, R, Abu, H, Abu-Arafeh, A, Abubacker, S, Abung, A, Abusamra, Y, Aceampong, Y, Achara, A, Acharya, D, Acheampong, S, Acheampong, P, Acheson, J, Achieng, S, Acosta, A, Acquah, R, Acton, C, Adabie-Ankrah, J, Adair, P, Adam, F, Adam, M, Adamali, H, Adamczyk, M, Adams, C, Adams, D, Adams, K, Adams, L, Adams, N, Adams, R, Adams, T, Adamu-Ikeme, L, Adati, K, Adcock, K, Addo, A, Adeagbo, O, Adebiyi, A, Adedeji, O, Adegeye, Y, Adegoke, K, Adell, V, Adenwalla, S, Adeoye, F, Adesemoye, O, Adewunmi, E, Adeyanju, A, Adeyemi, J, Adeyemo, T, Adhikary, R, Aditya, A, Adkins, G, Adnan, A, Aeron-Thomas, J, Affleck, D, Afnan, C, Afridi, M, Aftab, Z, Agarwal, M, Agbeko, R, Agbo, C, Aggarwal, S, Aghababaie, A, Aguilar Jimenez, L, Ahamed Sadiq, S, Ahammed Nazeer, M, Ahmed, A, Ahmed, B, Ahmed, F, Ahmed, H, Ahmed, I, Ahmed, K, Ahmed, L, Ahmad, M, Ahmed, N, Ahmed, O, Ahmed, R, Ahmad, S, Ahmed, S H, Ahmed Ali, R, Ahmed Mohamud, B, Ahmer, S, Ahonia, A, Aiken, C, Ail, D, Ainsworth, M, Aissa, M, Aitken, L, Ajay, B, Ajibode, A, Ajmi, A, Akhtar, N, Akili, S, Akinbiyi, B, Akindolie, O, Akinfenwa, Y, Akinkugbe, O, Akinpelu, I, Akram, M, Aktinade, O, Akudi, U, Al Aaraj, A, Al Balushi, A, Al Dakhola, M, Al Swaifi, A, Al-Abadi, E, Alabi, A, Aladangady, N, Alafifi, M, Alam, A, Alam, S, Al-Asadi, A, Alatzoglou, K, Albert, P, Albon, L, Alcala, A, Alcorn, G, Alcorn, S, Aldana, A, Alderdice, D, Aldesouki, A, Aldouri, R, Aldridge, J, Aldridge, N, Alegria, A, Alexander, C, Alexander, J, Alexander, P, Al-Fori, J, Alghazawi, L, Alhabsha, O, Al-Hakim, B, Alhameed, R, Al-Hayali, M, Al-Hity, S, Ali, A, Ali, F, Ali, J, Ali, M, Ali, N, Ali, O, Ali, R, Ali, S, Aliberti, E, Alin, J, Alina, A, Alipustain, A, Aliyuda, F, Alizaedeh, K, Al-Jibury, M, Al-Juboori, S, Al-Khalil, M, Alkhudhayri, A, Alkhusheh, M, Allan, F, Allan, N, Allanson, A, Allcock, R, Allen, E, Allen, J, Allen, K, Allen, L, Allen, P, Allen, R, Allen, S, Allen, T, Alli, A, Allison, K, Allman, B, Allsup, D, Allsop, H, Allsop, L, Almahroos, A, Al-Moasseb, H, Al-Obaidi, M, Alomari, L, Al-Rabahi, A, Al-Ramadhani, B, Al-Saadi, Z, Al-Sammarraie, R, Alshaer, I, Al-Shahi Salman, R, Al-Shamkhani, W, Alsheikh, F, Al-Sheklly, B, Altaf, S, Alty, A, Alvarez, M, Alvarez Corral, M, Alveyn, E, Alzetani, M, Amamou, S, Amar, N, Ambalavanan, S, Ambrogetti, R, Ambrose, C, Ameen, A, Ames, K, Amin, A, Amin, K, Amin, S, Amin, T, Amit, B, Amjad, A, Amjad, N, Amosun, V, Amsal, M, Amsha, K, Amutio Martin, N, Amy, P, Anada, A, Anand, A, Anandappa, S, Anantapatnaikuni, S, Anderson, E, Anderson, J, Anderson, L, Anderson, M, Anderson, N, Anderson, R, Anderson, S, Anderson, W, Andreou, P, Andrews, A, Andrews, J, Aneke, K, Ang, A, Ang, W, Angel, T, Angela, A, Angelini, P, Anguvaa, L, Anichtchik, O, Anim-Somuah, M, Aniruddhan, K, Annett, J, Anning, L, Anstey, P, Anstey, R, Anthony, A, Anthony-Pillai, A, Antill, P, Antonnia, Z, Anu, V, Anwar, M, Apetri, E, Apostolopoulos, A, Appleby, S, Appleyard, D, Aquino, M, Araba, B, Aransiola, S, Araujo, M, Archer, A, Archer, D, Archer, S, Arcoria, D, Ardley, C, Arias, A, Aribike, O, Arimoto, R, Armata, I, Armistead, J, Armitage, A, Armstrong, C, Armstrong, M, Armstrong, S, Armstrong, W, Armtrong, P, Arndt, H, Arnison-Newgass, C, Arnold, D, Arnold, R, Arnott, A, Arora, D, Arora, R, Arora, K, Arora, P, Arter, A, Arumaithurai, A, Arya, A, Arya, R, Asandei, D, Asghar, M, Ashab, M, Ashbrook-Raby, C, Ashby, H, Ashcroft, J, Ashcroft, S, Asher, G, Ashfak, Z, Ashfaq, A, Ashish, A, Ashley, D, Ashman-Flavell, S, Ashok, S, Ashour, A, Ashraf, S, Ashraf, M, Ashraq, M, Ashton, D, Ashton, S, Ashworth, A, Ashworth, F, Ashworth, R, Aslam, A, Aslam, I, Aslam, S, Aslett, L, Asogan, H, Asrar, A, Assaf, O, Astin-Chamberlain, R, Athorne, D, Atkins, B, Atkins, C, Atkins, S, Atkinson, J, Atkinson, V, Atomode, A, Atraskiewicz, B, Attia, A, Attubato, E, Attwood, M, Auer, Z, Aujayeb, A, Aung, A, Aung, H, Aung, K, Aung, N, Aung, Y, Aung, Z, Austin, E, Austin, K, Auwal, A, Avari, M, Avery, M, Aveyard, N, Avis, J, Aviss, G, Avram, C, Avram, P, Awadelkareem, A, Awadzi, G, Awaly, M, Awan, A, Awoseyila, A, Aya, A, Ayaz, E, Ayers, A, Azam, J, Azeem, A, Azharuddin, M, Aziz, A, Aziz, G, Aziz, I, Aziz, N, Azkoul, A, Azman Shah, A, Azzopardi, G, Azzoug, H, Babatunde, F, Babi, M, Babiker, B, Babington, G, Babirecki, M, Babores, M, Babs-Osibodu, A, Bacciarelli, S, Bachar, R, Bachour, M, Bacon, G, Bacon, J, Badal, B, Bader, M, Badhan, G, Badhrinarayanan, S, Bae, J, Baggaley, A, Baggott, A, Bagmane, D, Bagshaw, L, Bahadori, K, Bailey, A, Bailey, J, Bailey, K, Bailey, L, Bailey, M, Bailey, P, Bailey, S, Baillie, H, Baillie, J, Bain, J, Bains, V, Baird, D, Baird, E, Baird, S, Baird, T, Baird, Y, Bajandouh, A, Baker, D, Baker, E, Baker, J, Baker, K, Baker, M, Baker, R, Baker, T, Baker, V, Bakere, H, Bakerly, N, Baker-Moffatt, M, Bakhai, A, Bakhtiar, N, Bakoulas, P, Bakthavatsalam, D, Balachandran, N, 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Zulaikha, R, Zulfikar, S, Zullo, C, and Zuriaga-Alvaro, A
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- 2024
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16. Enhancing photovoltaic materials: DFT insights into structural modification of benzo [1, 2-b: 4, 5-b1]dithiophene unit (BDT)-based molecule
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Doust Mohammadi, Mohsen, Abbas, Faheem, Louis, Hitler, Amadu, Ismail O., Khalid, Maria, and Gber, Terkumbur E.
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- 2024
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17. Influence of alkaline-earth metals (B = Be, Mg, Ca) doping on the structural, electronic, optoelectronic, thermodynamic, and core-level spectroscopic studies of CsBCl3 halide perovskites
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Ikot, Immaculata J., Louis, Hitler, Ogunwale, Goodness J., Amodu, Ismail O., Ashishie, Providence B., Ekeng-ita, Emmanuel, and Adeyinka, Adedapo S.
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- 2023
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18. Chemical characterisation of sulfated polysaccharides from the red seaweed Centroceras clavulatum and their in vitro immunostimulatory and antioxidant properties
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Uzeme P. Aluta, Ademola Z. Aderolu, Ismail O. Ishola, Mohammad Alyassin, Gordon A. Morris, and Olumayokun A. Olajide
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Centroceras clavulatum ,Sulfated polysaccharides ,Carp leukocyte culture ,Reactive intermediates ,Antioxidant activity ,Nutrition. Foods and food supply ,TX341-641 ,Nutritional diseases. Deficiency diseases ,RC620-627 - Abstract
Phycocolloids have aroused research interest due to their remarkable functional properties, including immunostimulatory and antioxidant activities. In this study, the yield of Centroceras clavulatum sulfated polysaccharides (CCSP) was 4.36% and had a sulfate content of 9.42%. The main monosaccharide units of CCSP were galactose (25.23 ± 0.81 mg/l) and glucose (4.32 ± 0.31 mg/l). Specifically, FT-IR spectrum of CCSP revealed a peak at 843 cm−1 which indicates the occurrence of sulfate groups on C-4 of galactose. CCSP stimulated Carp Leukocyte Culture (CLC) cell line to generate reactive oxygen species (ROS) and nitric oxide (NO) in a dose-dependent manner. Remarkably, exposure of CLC cells to CCSP at a dose of 12.5 µg/ml significantly increased superoxide dismutase activity and reduced malondialdehyde level. These results suggest that CCSP could stimulate CLC cells without compromising the intracellular antioxidant system, hence, may have potential applications as nutraceuticals.
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- 2023
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19. Chemical characterisation of sulfated polysaccharides from the red seaweed Centroceras clavulatum and their in vitro immunostimulatory and antioxidant properties
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Aluta, Uzeme P., Aderolu, Ademola Z., Ishola, Ismail O., Alyassin, Mohammad, Morris, Gordon A., and Olajide, Olumayokun A.
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- 2023
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20. Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
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Abani, O, Abbas, A, Abbas, F, Abbas, J, Abbas, K, Abbas, M, Abbasi, S, Abbass, H, Abbott, A, Abdallah, N, Abdelaziz, A, Abdelfattah, M, Abdelqader, B, Abdul, A, Abdul, B, Abdul, S, Abdul Rasheed, A, Abdulakeem, A, Abdul-Kadir, R, Abdullah, A, Abdulmumeen, A, Abdul-Raheem, R, Abdulshukkoor, N, Abdusamad, K, Abed El Khaleq, Y, Abedalla, M, Abeer Ul Amna, A, Abel, L, Abernethy, K, Abeywickrema, M, Abhinaya, C, Abidin, A, Aboaba, A, Aboagye-Odei, A, Aboah, C, Aboelela, H, Abo-Leyah, H, Abouelela, K, Abou-Haggar, A, Abouibrahim, M, Abousamra, A, Abouzaid, M, Abraham, M, Abraham, T, Abraheem, A, Abrams, J, Abrams, R, Abu, HJ, Abu-Arafeh, A, Abubacker, SM, Abung, A, Abusamra, Y, Aceampong, Y, Achara, A, Acharya, D, Acheampong, F, Acheampong, P, Acheampong, S, Acheson, J, Achieng, S, Acosta, A, Acquah, R, Acton, C, Adabie-Ankrah, J, Adair, P, Adam, AS, Adam, F, Adam, M, Adamali, H, Adamczyk, M, Adams, C, Adams, D, Adams, K, Adams, L, Adams, N, Adams, R, Adams, T, Adamu-Ikeme, L, Adatia, K, Adcock, K, Addai-Boampong, L, Addo, A, Adeagbo, O, Adebiyi, A, Adedeji, O, Adegeye, Y, Adegoke, K, Adell, V, Adenwalla, S, Adeoye, FW, Adesemoye, OA, Adewunmi, EO, Adeyanju, A, Adeyemi, J, Adeyemo, T, Adhikari, B, Adhikari, SA, Adhikary, R, Aditya, A, Adjepong, P, Adkins, G, Adnan, A, Adriaanse, M, Aeron-Thomas, J, Affleck, D, Afnan, C, Afridi, M, Afrim, P, Afriyie, FA, Aftab, ZA, Afum-Adjei Awuah, A, Agarwal, M, Agasiya, PN, Agbeko, R, Agbo, C, Aggarwal, S, Aghababaie, A, Aguilar Jimenez, L, Agyekum, JA, Agyen, K, Ahadome, EK, Ahamed Sadiq, S, Ahammed Nazeer, MH, Ahmad, M, Ahmad, S, Ahmed, A, Ahmed, BAR, Ahmed, B, Ahmed, F, Ahmed, H, Ahmed, I, Ahmed, K, Ahmed, L, Ahmed, M, Ahmed, MC, Ahmed, MS, Ahmed, N, Ahmed, O, Ahmed, RA, Ahmed, R, Ahmed, S, Ahmed, SG, Ahmed, SH, Ahmed Ali, R, Ahmed Mohamud, B, Ahmer, S, Ahonia, A, Aidoo, C, Aiken, C, Ail, D, Ainsworth, M, Aissa, M, Aitken, L, Ajay, B, Ajibode, A, Ajmi, A, Akhtar, N, Akili, S, Akinbiyi, B, Akindolie, O, Akinfenwa, Y, Akinkugbe, O, Akinpelu, I, Akram, M, Aktinade, O, Akudi, U, Al Aaraj, ASAR, Al Balushi, A, Al Dakhola, M, Al Swaifi, A, Al-Abadi, E, Alabi, A, Aladangady, N, Alafifi, M, Alam, A, Alam, S, Al-Asadi, A, Alatzoglou, K, Albert, P, Albertus, A, Albon, L, Alcala, A, Alcorn, G, Alcorn, S, Aldana, A, Alderdice, D, Aldesouki, A, Aldouri, R, Aldridge, J, Aldridge, N, Ale, RM, Alegria, A, Alexander, A, Alexander, C, Alexander, J, Alexander, PDG, Al-fori, J, Alghazawi, L, Alhabsha, O, Al-Hakim, B, Alhameed, R, Al-Hayali, M, Al-Hity, S, Ali, A, Ali, FR, Ali, J, Ali, M, Ali, MS, Ali, N, Ali, O, Ali, R, Ali, S, Aliberti, E, Alin, J, Alina, A, Alipustain, A, Alisjahbana, B, Aliyuda, F, Alizadeh, K, Al-Jibury, M, Al-Juboori, S, Al-Khalil, M, Alkhudhayri, A, Alkhusheh, M, Allan, F, Allan, N, Allanson, A, Allcock, R, Allen, E, Allen, J, Allen, K, Allen, L, Allen, P, Allen, R, Allen, S, Allen, T, Alli, A, Allison, K, Allman, B, Allsop, HK, Allsop, L, Allsup, D, Almahroos, AFT, Al-Moasseb, H, Al-Obaidi, M, Alomari, L, Al-Rabahi, A, Al-Ramadhani, B, Al-Saadi, Z, Al-Sammarraie, R, Alshaer, I, Al-Shahi Salman, R, Al-Shamkhani, W, Alsheikh, F, Al-Sheklly, B, Altaf, S, Alty, A, Alvarez, M, Alvarez Corral, M, Alveyn, E, Alzetani, M, Amamou, S, Amar, N, Ambalavanan, S, Ambrogetti, R, Ambrose, C, Ameen, A, Amelia Ganefianty, A, Ames, K, Amezaga, MR, Amin, A, Amin, K, Amin, S, Amin, T, Amit, B, Amjad, A, Amjad, N, Amoah-Dankwa, J, Amoako-Adusei, A, Amosun, V, Amsal, M, Amsha, K, Amuasi, J, Amutio Martin, N, Amy, P, Anada, A, Anand, A, Anandappa, S, Anantapatnaikuni, SD, Andari, NKN, Anderson, E, Anderson, J, Anderson, L, Anderson, M, Anderson, N, Anderson, R, Anderson, S, Anderson, W, Andreou, P, Andrews, A, Andrews, J, Aneke, K, Ang, A, Ang, WW, Angel, T, Angela, A, Angelini, P, Anguvaa, L, Anichtchik, O, Anim-Somuah, M, Aniruddhan, K, Annett, J, Anning, L, Ansah, M, Anstey, PJ, Anstey, R, Anthony, A, Anthony-Pillai, A, Antill, P, Antonina, Z, Anu, V, Anwar, M, Anwar, S, Apetri, E, Apostolopoulos, A, Appleby, S, Appleyard, D, Aquino, MF, Araba, B, Aransiola, S, Araujo, M, Archer, A, Archer, D, Archer, S, Arcoria, D, Ardley, C, Arhin-Sam, G, Arias, A-M, Aribike, O, Arimoto, R, Arisanti, NLPE, Arkley, C, Armah, C, Armata, I, Armistead, J, Armitage, A, Armstrong, C, Armstrong, M, Armstrong, S, Armstrong, W, Armtrong, P, Arndt, H, Arnison-Newgass, C, Arnold, D, Arnold, R, Arnott, A, Arora, D, Arora, K, Arora, P, Arora, R, Arter, A, Arthur, A, Artini, NM, Arumaithurai, A, Arya, A, Arya, R, Aryal, D, Asandei, D, Asare, GA, Asghar, A, Asghar, M, Ashab, A, Ashbrook-Raby, C, Ashby, H, Ashcroft, J, Ashcroft, S, Asher, G, Ashfak, Z, Ashfaq, A, Asiamah, HA, Ashish, A, Ashley, D, Ashman-Flavell, S, Ashok, S, Ashour, A-E-A, Ashraf, MZ, Ashraf, S, Ashraq, MB, Ashton, D, Ashton, S, Ashworth, A, Ashworth, FJ, Ashworth, R, Aslam, A, Aslam, I, Aslam, S, Aslett, L, Asogan, H, Asrar, A, Assaf, O, Astin-Chamberlain, R, Atabudzi, YE, Athavale, P, Athorne, D, Atkins, B, Atkins, C, Atkins, S, Atkinson, J, Atkinson, V, Atomode, A, Atraskiewicz, B, Attia, AA, Attubato, E, Attwood, M, Aubrey, P, Auer, Z, Aujayeb, A, Aung, AT, Aung, H, Aung, HWW, Aung, KK, Aung, KT, Aung, N, Aung, Y, Aung, ZM, Austin, E, Austin, K, Auwal, A, Avari, M, Avery, M, Aveyard, N, Avis, J, Aviss, G, Avram, C, Avram, P, Awadelkareem, A, Awadzi, G, Awaly, M, Awan, A, Awisi, S, Aya, A, Ayaz, E, Ayerh, JM, Ayers, A, Azam, J, Azeem, A, Azharuddin, M, Aziz, A, Aziz, G, Aziz, I, Aziz, N, Azkoul, A, Azman Shah, A, Azzopardi, G, Azzoug, H, Babatunde, F, Babi, M, Babiker, B, Babington, G, Babirecki, M, Babores, M, Babs-Osibodu, AO, Bac, T, Bacciarelli, S, Bachar, R, Bachour, M-E, Bachti, A, Bacon, G, Bacon, J, Badal, B, Badat, A, Bader, M, Badhan, GR, Badhrinarayanan, S, Bae, JP, Baggaley, A, Baggott, A, Bagley, G, Bagmane, D, Bagshaw, L, Bahadori, K, Bahurupi, Y, Bailey, A, Bailey, J, Bailey, K, Bailey, L, Bailey, MA, Bailey, M, Bailey, P, Bailey, S, Baillie, H, Baillie, JK, Bain, J, Bains, V, Baird, D, Baird, E, Baird, K, Baird, S, Baird, T, Baird, Y, Bajandouh, A, Baker, DC, Baker, E, Baker, J, Baker, K, Baker, M, Baker, R, Baker, T-A, Baker, V, Bakere, H, Bakerly, N, Baker-Moffatt, M, Bakhai, A, Bakhtiar, N, Bakoulas, P, Bakthavatsalam, D, Balachandran, N, Balan, A, Balasingam, P, Balaskas, T, Balasubramaniam, M, Balatoni, N, Balcombe, A, Baldwin, A, Baldwin, C, Baldwin, D, Baldwin, F, Baldwin-Jones, R, Bale, N, Balfour, J, Ball, M, Ball, Ro, Ballard, K, Balluz, I, Balmforth, C, Balogh, E, Baltmr, A, Baluwala, A, Bambridge, G, Bamford, A, Bamford, P, Bamgboye, A, Bancroft, E, Bancroft, H, Banda, J, Bandaru, K, Bandi, S, Bandla, N, Bandyopadhyam, S, Banerjee, A, Banerjee, R, Bang, P, Baniya, S, Bani-Saad, O, Banks, H, Banks, L, Banks, P, Bann, C, Bannister, H, Bannister, O, Banton, L, Bao, T, Baptist, M, Baqai, T, Baral, AM, Baral, SC, Baramova, D, Barber, R, Barbon, E, Barbosa, M, Barbour, J, Barclay, A, Barclay, C, Bardsley, G, Bareford, S, Bari, S, Barimbing, M, Barker, A, Barker, D, Barker, E, Barker, H, Barker, J, Barker, L, Barker, O, Barker-Williams, K, Barkha, S, Barla, J, Barlow, G, Barlow, R, Barlow, V, Barnacle, J, Barnard, A, Barnes, D, Barnes, N, Barnes, R, Barnes, T, Barnetson, C, Barnett, A, Barnett-Vanes, A, Barning, PG, Barnsley, W, Barr, A, Barr, D, Barr, J, Barr, C, Barratt, N, Barratt, S, Barrera, M, Barrett, A, Barrett, Fi, Barrett, J, Barrett, S, Barrow, E, Bartholomew, J, Barthwal, MS, Bartlett, C, Bartlett, G, Bartlett, J, Bartlett, L, Bartley, S, Bartolmeu-Pires, S, Barton, A, Barton, G, Barton, J, Barton, L, Barton, R, Baruah, R, Baryschpolec, S, Bashir, H, Bashyal, A, Basker, B, Basnet, S, Basnyat, B, Basoglu, A, Basran, A, Bassett, J, Bassett, G, Bassford, C, Bassoy, B, Bastion, V, Bastola, A, Basumatary, A, Basvi, P, Batac, JA, Bataduwaarachchi, VR, Bate, T, Bateman, HJ, Bateman, K, Bateman, V, Bates, E, Bates, H, Bates, M, Bates, S, Batham, S, Batista, A, Batla, A, Batra, D, Batty, H, Batty, T, Batty, A, Baum, M, Baumber, R, Bautista, C, Bawa, F, Bawa, T, Bawani, FS, Bax, S, Baxter, M, Baxter, N, Baxter, Z, Bayes, H, Bayo, L-A, Bazari, F, Bazaz, R, Bazli, A, Beacham, L, Beadles, W, Beadon, K, Beak, P, Beale, A, Beard, K, Bearpark, J, Beasley, A, Beattie, S, Beaumont, K, Beaumont-Jewell, D, Beaver, T, Beavis, S, Beazley, C, Beck, S, Beckett, V, Beckitt, R, Beckley, S, Beddall, H, Beddows, S, Beeby, D, Beeby, S, Beech, G, Beecroft, M, Beer, N, Beer, Sa, Beety, J, Bega, G, Begg, A, Begg, S, Beghini, S, Begum, A, Begum, S, Behan, T, Behrouzi, R, Beishon, J, Beith, C, Belcher, J, Belfield, H, Belfield, K, Belgaumkar, A, Bell, D, Bell, G, Bell, J, Bell, L, Bell, N, Bell, P, Bell, S, Bellamu, J, Bellamy, M, Bellamy, T, Bellini, A, Bellis, A, Bellis, F, Bendall, L, Benesh, N, Benetti, N, Bengu, SA, Benham, L, Benison-Horner, G, Benkenstein, S, Benn, T, Bennett, A, Bennett, C, Bennett, D, Bennett, G, Bennett, K, Bennett, L, Bennett, MR, Bennett, S, Bennion, K, Benoy, G, Benson, V, Bentley, A, Bentley, J, Benton, I, Beranova, E, Beresford, M, Bergin, C, Bergstrom, M, Bernatoniene, J, Berriman, T, Berry, Z, Best, F, Best, K, Bester, A-M, Beuvink, Y, Bevan, E, Bevins, S, Bewick, T, Bexley, A, Beyatli, S, Beynon, F, Bhadi, A, Bhagani, S, Bhakta, S, Bhalla, R, Bhandal, K, Bhandari, A, Bhandari, LN, Bhandari, S, Bhanich Supapol, J, Bhanot, A, Bhanot, R, Bhasin, S, Bhat, A, Bhat, P, Bhatnagar, R, Bhatt, K, Bhayani, J, Bhojwani, D, Bhuie, P, Bhuiyan, MS, Bhuiyan, S, Bibby, A, Bibi, F, Bibi, N, Bibi, S, Bicanic, T, Bidgood, S, Bigg, J, Biggs, S, Biju, A, Bikov, A, Billingham, S, Billings, J, Binh, P, Binns, A, BinRofaie, M, Bintcliffe, O, Birch, C, Birch, J, Birchall, K, Bird, S, Birt, M, Bishop, C, Bishop, K, Bishop, L, Bisnauthsing, K, Biswas, N, Bittaye, M, Biuk, S, Blachford, K, Black, E, Black, H, Black, K, Black, M, Black, P, Black, V, Blackgrove, H, Blackledge, B, Blackler, J, Blackley, S, Blackman, H, Blackstock, C, Blair, C, Blakemore, F, Blamey, H, Bland, A, Blane, S, Blankley, S, Blaxill, P, Blaylock, K, Blazeby, J, Blencowe, N, Bloom, B, Bloomfield, J, Bloss, A, Blowers, A, Blows, S, Bloxham, H, Blrd, S, Blundell, L, Blunsum, A, Blunt, M, Blunt, T, Blyth, I, Blyth, K, Blythe, A, Blythe, K, Boahen, KA, Boampoaa, M, Board, S, Boatemah, E, Bobie, B, Bobruk, K, Bodalia, PN, Bodasing, N, Boden, M, Bodenham, T, Boehmer, G, Boffito, M, Bohanan, K, Bohmova, K, Bohnacker, N, Bokhandi, S, Bokhar, M, Bokhari, S, Bokhari, SO, Bokobza, I, Boles, A, Bolger, C, Bonaconsa, C, Bond, C, Bond, H, Bond, S, Bond, T, Bone, A, Boniface, G, Bonney, J, Bonney, L, Booker, L, Boot, S, Boothroyd, M, Borbone, J, Borman, N, Bosence, S, Bostock, K, Botting, N, Bottrill, F, Bouattia, H, Bough, L, Boughton, H, Boult, Z, Boumrah, T, Bourke, M, Bourke, S, Bourne, M, Bousfield, R, Boustred, L, Bowes, A, Bowker, P, Bowker, T, Bowler, H, Bowman, L, Bowman, S, Bowmer, R, Bowring, A, Bowyer, H, Boyd, A, Boyd, J, Boyd, L, Boyer, N, Boyle, N, Boyle, P, Boyle, R, Boyles, L, Brace, L, Bracken, A, Bradder, J, Bradley, CJ, Bradley, P, Bradley-Potts, J, Bradshaw, L, Bradshaw, Z, Brady, C, Brady, R, Brady, S, Braga Sardo, P, Braganza, D, Braithwaite, M, Brammer, S, Branch, M, Brankin-Frisby, T, Brannigan, J, Brattan, S, Bray, F, Bray, N, Brazil, M, Brear, L, Brear, Tr, Brearey, S, Bremner, L, Brend, M, Bresges, C, Bressington, C, Bretland, G, Brewer, C, Bridgett, M, Bridgwood, G, Brigham, S, Bright, J, Brightling, C, Brigstock, T, Brimfield, L, Brinksman, P, Brinkworth, E, Brittain-Long, R, Britten, V, Britton, H, Broad, L, Broadhead, S, Broadhurst, R, Broadley, A, Broadway, M, Brockelsby, C, Brocken, M, Brockley, T, Brodsky, M, Brogan, F, Brohan, L, Brokke, F, Brolly, J, Bromley, D, Brooke-Ball, H, Brooker, V, Brookes, M, Brooking, D, Brooks, A, Brooks, D, Brooks, J, Brooks, K, Brooks, N, Brooks, P, Brooks, R, Brooks, S, Broom, M, Broomhead, N, Broughton, C, Broughton, N, Brouns, M, Brown, A, Brown, C, Brown, E, Brown, H, Brown, J, Brown, L, Brown, N, Brown, P, Brown, R, Brown, S, Brown, T, Browne, B, Browne, C, Browne, D, Browne, M, Brownlee, S, Brraka, A, Bruce, J, Bruce, M, Brudlo, W, Brunchi, A, Brunskill, N, Brunton, A, Brunton, M, Bryant, M, Bryden, E, Brzezicki, H, Buazon, A, Buch, MH, Buchan, R, Buchanan, R, Buche, D, Buck, A, Buck, L, Buckland, M, Buckley, C, Buckley, L, Buckley, P, Buckley, S, Buckman, C, Budds, A, Bugg, G, Bujazia, R, Bukhari, M, Bukhari, S, Bulbulia, R, Bull, A, Bull, D, Bull, K, Bull, R, Bull, Th, Bullock, E, Bullock, S, Bulteel, N, Bumunarachchi, K, Bungue-Tuble, R, Burbidge, O, Burchett, C, Burda, D, Burden, C, Burden, TG, Burgess, Mi, Burgess, R, Burgess, S, Burhan, E, Burhan, H, Burke, H, Burke, K, Burman, A, Burnard, S, Burnett, C, Burnett, S, Burns, A, Burns, C, Burns, J, Burns, K, Burrage, D, Burrows, K, Burston, C, Burton, A, Burton, B, Burton, F, Burton, H, Burton, M, Butar butar, M, Butcher, D, Butler, A, Butler, E, Butler, J, Butler, P, Butler, S, Butt, A-T, Butt, M, Butt, MM, Butterworth, C, Butterworth-Cowin, N, Buttery, R, Buttle, T, Button, H, Buttress, D, Bye, H, Byrne, J, Byrne, W, Byrne-Watts, V, Cabandugama, A, Cabrero, L, Caddy, S, Cade, R, Cadwgan, A, Cahilog, Z, Cahyareny, A, Cairney, D, Calderwood, J, Caldow, D, Cale, E, Calisti, G, Callaghan, D, Callaghan, J, Callens, C, Callum, D, Calver, C, Cambell-Kelly, M, Camburn, T, Cameron, DR, Cameron, E, Cameron, F, Cameron, S, Camm, C, Cammack, FD, Campbell, A, Campbell, B, Campbell, D, Campbell, H, Campbell, J, Campbell, K, Campbell, M, Campbell, R, Campbell, W, Campbell Hewson, Q, Camsooksai, J, Canclini, L, Candido, SM, Candlish, J, Caneja, C, Cann, A, Cann, J, Cannan, R, Cannon, A, Cannon, E, Cannon, M, Cannon, P, Cannons, V, Canonizado, E, Cantliff, J, Cap, N, Caplin, B, Capocci, S, Caponi, N, Capp, A, Capstick, R, Capstick, T, Caraenache, C, Card, A, Cardwell, M, Carey, C, Carey, R, Carley, S, Carlin, F, Carlin, T, Carmichael, S, Carmody, M, Carnahan, M, Caroline, C, Carpenter, J, Carr, S, Carrasco, A, Carrington, Z, Carroll, A, Carroll, P, Carson, R, Cart, C, Carter, E, Carter, J, Carter, M, Carter, N, Carter, P, Cartwright, D, Cartwright, J-A, Carty, C, Carty, L, Carungcong, J, Carver, C, Carver, E, Carver, R, Casey, S, Cassells, A, Castiello, T, Castle, G, Castles, B, Caswell, M, Catana, AM, Cate, H, Catelan Zborowski, A, Cathcart, S, Cathie, K, Catibog, D, Catley, C, Catlow, L, Caudwell, M, Cavazza, A, Cave, A, Cave, L, Cavinato, S, Cawa, F, Cawley, K, Caws, C, Cawthorne, K, Cendl, H, Century, H, Cernova, J, Cesay, M, Cetti, E, Chabane, S, Chablani, M, Chabo, C, Chacko, J, Chadwick, D, Chadwick, J, Chadwick, R, Chakkarapani, E, Chakraborty, A, Chakraborty, M, Chakravorty, M, Chalakova, P, Chalise, BS, Chalmers, J, Chalmers, R, Chamberlain, G, Chamberlain, S, Chambers, E, Chambers, J, Chambers, L, Chambers, N, Chan, A, Chan, C, Chan, E, Chan, M, Chan, K, Chan, P, Chan, R (P-C), Chan, XHS, Chandler, C, Chandler, H, Chandler, KJ, Chandler, S, Chandler, Z, Chandra, S, Chandran, N, Chandrasekaran, B, Chang, Y, Chanh, HQ, Chaplin, G, Chaplin, J, Chapman, G, Chapman, J, Chapman, K, Chapman, L, Chapman, M, Chapman, P, Chapman, T, Chappell, L, Charalambou, A, Charles, B, Charlton, D, Charlton, S, Chatar, K, Chatha, C, Chatterton, D, Chau, N, Chaube, R, Chaudhary, MYN, Chaudhary, B, Chaudhry, I, Chaudhry, Z, Chaudhuri, K, Chaudhuri, N, Chaudhury, M, Chauhan, A, Chauhan, RS, Chavasse, A, Chavasse, N, Chawla, V, Cheater, L, Cheaveau, J, Cheeld, C, Cheeseman, M, Chen, F, Chen, HM, Chen, T, Cheng, F, Cheng, LY, Cheng, Z, Chenoweth, H, Cheong, CH, Cherian, JJ, Cherian, S, Cherrie, M, Cheshire, H, Cheung, CK, Cheung, E, Cheung, K, Cheung, M, Cheyne, C, Chhabra, S, Chia, WL, Chiang, E, Chiapparino, A, Chicano, R, Chikara, G, Chikungwa, M, Chikwanha, ZA, Chilcott, G, Chilcott, S, Chilvers, A, Chimbo, P, Chin, KW, Chin, WJ, Chineka, R, Chingale, A, Chinonso, E, Chin-Saad, C, Chirgwin, M, Chisem, H, Chisenga, C, Chisholm, C, Chisnall, B, Chiswick, C, Chita, S, Chitalia, N, Chiu, M, Chiverton, L, Chivima, B, Chmiel, C, Choi, S, Choon Kon Yune, W, Chopra, M, Choudhary, V, Choudhury, O, Choudhury, S, Chow, B-L, Chowdhury, M, Chowdhury, S, Chrisopoulou, A, Christenssen, V, Christian, P, Christides, A, Christie, F, Christmas, D, Christoforou, G, Christopherson, T, Christou, A, Christy, M, Chrysostomou, P, Chua, Y, Chudgar, D, Chudleigh, R, Chukkambotla, S, Chukwu, ME, Chukwulobelu, I, Chung, CY, Church, E, Church, SR, Churchill, D, Cianci, N, Cicconi, P, Cinardo, P, Cipinova, Z, Cipriano, B, Clamp, S, Clancy, B, Clapham, M, Clare, E, Clare, S, Clark, A, Clark, C, Clark, D, Clark, E, Clark, F, Clark, G, Clark, J, Clark, K, Clark, L, Clark, M, Clark, N, Clark, P, Clark, R, Clark, T, Clark, Z, Clarke, A, Clarke, J, Clarke, P, Clarke, R, Clarke, S, Claxton, A, Claxton, L, Clay, K, Clayton, C, Clayton, E, Clayton, O, Clayton-Smith, J, Clearyb, B, Cleaver, C, Cleeton, R, Clement, I, Clemente de la Torre, C, Clements, J, Clements, S, Clenton, S, Cliff, S, Clifford, R, Clifford, S, Clive, A, Clouston, J, Clubb, V, Clueit, S, Clutterbuck, L, Clyne, A, Coakley, M, Coakley, PGL, Cobain, K, Cochrane, A, Cochrane, P, Cockayne, L, Cockerell, M, Cockerill, H, Cocks, S, Codling, R, Coe, A, Coetzee, S, Coey, D, Cohen, D, Cohen, J, Cohen, O, Cohn, M, Coke, L, Coker, O, Colbeck, N, Colbert, R, Cole, E, Cole, J, Coleman, G, Coleman, M, Coleman, N, Coles, H, Colin, M, Colino-Acevedo, A, Colley, J, Collie, K, Collier, A, Collier, D, Collier, H, Collingwood, T, Collini, P, Collins, E, Collins, J, Collins, K, Collins, M, Collins, N, Collins, S, Collins, V, Collinson, A, Collinson, B, Collinson, J, Collis, M, Colmar, M, Colton, HE, Colton, J, Colville, K, Colvin, C, Combes, E, Comer, D, Comerford, A, Concannon, D, Condliffe, A, Condliffe, R, Connell, E, Connell, L, Connell, N, Connelly, K, Connolly, G, Connor, E, Conroy, A, Conroy, K, Conteh, V, Convery, R, Conway, F, Conway, G, Conway, R, Conyngham, J-A, Cook, A, Cook, C, Cook, E, Cook, G, Cook, H, Cook, J, Cook, M, Cook, S, Cooke, D, Cooke, G, Cooke, H, Cooke, 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von Oven, L, Vooght, C, Vu Thai, KT, Vutipongsatorn, K, Vuylsteke, A, Vyras, E, Wach, R, Wadams, B, Wadd, S, Waddington, N, Wade, P, Wadsley, J, Wadsworth, K, Wafa, SEI, Wagstaff, D, Wagstaff, L, Wahab, D, Wahbi, Z, Waheed Adigun, A, Waidyanatha, S, Waite, A, Wake, R, Wakefield, A, Wakeford, W, Wakinshaw, F, Waldeck, E, Walden, A, Walding, L, Waldron, A, Waldron, J, Wales, E, Wali, B, Walker, D, Walker, G, Walker, H, Walker, I, Walker, K, Walker, L, Walker, O, Walker, R, Walker, S, Wallace, G, Wallbutton, R, Wallen, J, Wallendszus, K, Waller, A, Waller, R, Wallis, G, Wallis, L, Wallis, M, Walmsley, E, Walsh, D, Walsh, E, Walsh, L, Walstow, D, Walter, D, Walters, A, Walters, H, Walters, J, Walton, E, Walton, L, Walton, M, Walton, O, Walton, S, Wan, M, Wanda, J, Wands, M, Wane, R, Wang, F, Wang, N, Wang, R, Wang, S, Warbrick, D, Warburton, S, Ward, C, Ward, D, Ward, E, Ward, H, Ward, J, Ward, L, Ward, N, Ward, R, Ward, T, Warden, SA, Wardere, G, Wardle, S, Wardy, H, Waring, G, Waring, S, 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Wongkyezeng, AA, Wood, A, Wood, C, Wood, D, Wood, F, Wood, G, Wood, H, Wood, J, Wood, L, Wood, M, Wood, S, Wood, T, Woodall, K, Woodfield, R, Woodford, C, Woodford, E, Woodford, J, Woodhead, L, Woodhead, T, Woodland, P, Woodman, M, Woodmansey, S, Woods, C, Woods, J, Woods, K, Woods, S, Woodward, Z, Woolcock, M, Wooldridge, G, Woolf, R, Woollard, C, Woollen, L, Woolley, E, Woolley, J, Woosey, D, Wootton, D, Wootton, J, Worley, D, Worton, S, Wraight, J, Wray, M, Wren, K, Wren, L, Wrey Brown, C, Wright, C, Wright, D, Wright, F, Wright, H, Wright, I, Wright, L, Wright, R, Wright, S, Wright, T, Wroe, C, Wroe, H, Wu, H, Wu, P, Wubetu, J, Wulandari, F, Wulandari, R, Wurie, S, Wyatt, C, Wyn-Griffiths, F, Wynter, I, Xavier, B, Xhikola, A, Xia, BE, Xia, Z, Yacoba, E, Yadav, S, Yakubi, M, Yan, M, Yanagisawa, Y, Yang, F, Yang, Y, Yanney, M, Yap, WL, Yaqoob, N, Yasmin, S, Yates, B, Yates, D, Yates, E, Yates, H, Yates, T, Yates, M, Ye, J, Yearwood Martin, C, Yein, K, Yelnoorkar, F, Yen, LM, Yeoh, A, Yeung, CY, Yew, P, Yewatkar, D, Ylquimiche Melly, L, Ynter, I, Yong, H, Yorke, J, Youens, J, Younes Ibrahim, A, Young, E, Young, G, Young, L, Yousafzar, A, Youssouf, S, Yousuf, A, Yovita, H, Yu, C, Yuan, JSJ, Yufaniaputri, N, Yung, B, Yusef, D, Yusef, S, Yusuf, I, Zafar, A-S, Zagalo, S, Zaher, S, Zahoor, A, Zainab, M, Zak, T, Zaki, K, Zakir, N, Zalewska, K, Zamalloa, A, Zaman, M, Zaman, S, Zamikula, J, Zammit, L, Zammit-Mangion, M, Zawadzka, M, Zayed, M, Zebracki, E, Zehnder, D, Zeidan, L, Zeinali, D, Zhang, J, Zhao, X, Zheng, D, Zhu, D, Zia, M, Zibdeh, O, Zill-E-Huma, R, Zin, ET, Zincone, E, Zindoga, G, Zinkin, E, Zinyemba, V, Zipitis, C, Zitter, L, Zmierczak, A, Zubikarai, G, Zubir, A, Zuhra, N, Zulaikha, R, Zulfikar, S, Zullo, C, and Zuriaga-Alvaro, A
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- 2023
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21. Standardized seed extract of Cajanus cajan (L) Millsp. produced antinociceptive and anti-inflammatory actions through inhibition of inflammatory mediators and activation of opioidergic signaling
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Olubodun-Obadun, Taiwo G., Ishola, Ismail O., Osumuo, Chisom A., and Adeyemi, Olufunmilayo O.
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- 2023
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22. Arctium lappa root extract based emulgels attenuate inducible cytokines and prostaglandins formation: Potential in the management of chronic inflammatory disorders
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Kola-Mustapha, Adeola Tawakalitu, Abdulrahman, Muhammed Olawale, and Ishola, Ismail O.
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- 2023
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23. Acute and sub-chronic oral exposure to ethanolic seed extract of Cajanus Cajan Millsp in rats: Biochemical and histological studies
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Olubodun-Obadun, Taiwo G., Ishola, Ismail O., Kusamotu, Olabode A., Ebu, Collins I., and Adeyemi, Olufunmilayo O.
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- 2023
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24. Modeling of Al12N12, Mg12O12, Ca12O12, and C23N nanostructured as potential anode materials for sodium-ion battery
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Louis, Hitler, Isang, Bartholomew B., Unimuke, Tomsmith O., Gber, Terkumbur E., Amodu, Ismail O., Ikeuba, Alexander I., and Adeyinka, Adedapo S.
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- 2023
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25. Arctium lappa root extract based emulgels attenuate inducible cytokines and prostaglandins formation: Potential in the management of chronic inflammatory disorders
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Adeola Tawakalitu Kola-Mustapha, Muhammed Olawale Abdulrahman, and Ismail O. Ishola
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Chronic inflammatory disorders ,Emulgel formulation ,Traditional medicine ,Arctium lappa ,Phytotherapy ,Science - Abstract
Background: Chronic inflammation contributes significantly to the burden suffered in many disease conditions in Africa with modern treatments often inaccessible to many. Phytotherapy presents a useful way to accelerate access to Universal health coverage with minimal incurred costs. The study was aimed at exploring the in vitro anti-inflammatory action and formulation of Arctium lappa root, a plant grown and available in different regions in Africa, as an herbal emulgel for the management of chronic inflammation Methods: Methanol root extract of Arctium lappa (0.25, 0.50 and 1.00 % w/w) was used for pre-formulation analysis. Phytochemical screening of the extract was done using the Harborne's standardized method for phytochemical analyses. In vitro anti-inflammatory activity was studied by evaluating inhibitory actions of the extracts on Prostaglandin-E (PGE), tumour necrotic factor-α (TNF-α) and cyclooxygenase II (COX-2) using Enzyme-Linked Immunosorbent Assay. Post formulation, the percentage inhibition of the pro-inflammatory cytokines by the herbal emulgels were compared with commercial diclofenac emulgel. The physicochemical properties of the herbal emulgels were also determined. Results: The preliminary qualitative phytochemical analysis of Arctium lappa root extract gave tannins, saponins, phenolics, steroids, glycosides, flavonoids, anthocyanin, terpenoids, and alkaloids as its contents. The extract's inhibitory activities on PGE-2, COX-2 and TNF-α were dose dependent. The formulated herbal emulgel showed that the activities of PGE-2, COX-2 and TNF-α were significantly inhibited in comparison with vehicle-treated control. The physical appearance (which reflected the concentration gradient of the Arctium lappa root extract in the emulgels), consistency and homogeneity of the emulgels were acceptable and spreadable. The pH and viscosity of the emulgels were from 4.97 ± 0.04 to 5.42 ± 0.05 and 3.36 ± 0.40 and 3.95 ± 0.50 Pas, respectively. Conclusion: Here, the emulgel of Arctium lappa root extract showed promising anti-inflammatory property evidenced in its ability to attenuate PGE-2, COX-2 and TNF-α activities in-vitro, which was similar to the effect of diclofenac (a currently used anti-inflammatory agent of synthetic origin). This study is novel, important and of great impact because it provides a useful indication of Arctium lappa as a topical agent in the management of chronic inflammatory disorders. As compared to previous studies, key advances in this research include the first successful attempt to formulate the root extract of Arctium lappa into an emulgel, advancing the application of pharmaceutics in phytotherapy for prospects of improved treatment of inflammation, especially in Africa; and this can be adapted globally beyond the region.
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- 2023
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26. Acute and sub-chronic oral exposure to ethanolic seed extract of Cajanus Cajan Millsp in rats: Biochemical and histological studies
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Taiwo G. Olubodun-Obadun, Ismail O. Ishola, Olabode A. Kusamotu, Collins I. Ebu, and Olufunmilayo O. Adeyemi
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Acute toxicity test ,Granulocytosis ,Lymphocytopenia ,Hematological ,Hormonal analysis ,Subchronic administration ,Science - Abstract
Background: Cajanus cajan (Leguminosae) seed is a perennial legume commonly consumed as food in tropical and semi-tropical regions. It also serves as medicine used in the treatment of various ailments. Hence, this study was designed to investigate the acute and 60-day subchronic toxicity effects of C. cajan ethanol seed extract (Cc) in rats. Methods: Adult Sprague rats (of both sexes) were treated with normal saline (NS) and Cc (20, 100, and 500 mg/kg per body weight, orally) for 60 consecutive days. Animals were weighed weekly as well as monitored for behavioral and morphological changes. At the end of the study, blood samples were collected for biochemical, hematological and hormonal analysis. Vital organs were also collected, weighed and assessed for histology. Results: In the acute toxicity study, no mortality was recorded following single oral administration of Cc up to 2000 mg/kg to mice. Similarly, Cc did not produce any significant (p> 0.05) adverse effects on body weights of vital organs (except for significant decrease in lung weight and increase in heart weight in female rats), Also, Cc caused was no significant effect (p> 0.05) in serum hormonal level, hematological, and biochemical parameters of rats. However, we observed a significant decrease (p
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- 2023
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27. Standardized seed extract of Cajanus cajan (L) Millsp. produced antinociceptive and anti-inflammatory actions through inhibition of inflammatory mediators and activation of opioidergic signaling
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Taiwo G. Olubodun-Obadun, Ismail O. Ishola, Chisom A. Osumuo, and Olufunmilayo O. Adeyemi
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Cyclooxygyenase-2 ,Inflammation ,Flavonoids ,Mu opioid receptor ,Molecular docking ,Nociception ,Other systems of medicine ,RZ201-999 - Abstract
Background and Purpose: Peripheral tissue damage and diseases could lead to persistent pain beyond possible resolution suggestive of disease-promoting condition which gives rise to chronic pain. The inability of current medications to manage some chronic inflammatory and painful conditions necessitate the need for better treatment options. Natural products have been a veritable source for the discovery of more efficacious and safer therapeutics. Cajanus cajan (L) Millsp, (Fabaceae) is used in traditional African medicines for the treatment of painful, gut disturbance and inflammatory conditions. Hence, the current study aims to investigate the anti-inflammatory and antinociceptive actions of the ethanol seed extract of Cajanus cajan (CC) in rodents and possible mechanisms of action. Methods: High performance liquid chromatography coupled with diode-array detection (HPLC-DAD) was used to identify 8 major flavonoids in CC. Antinociceptive activity was investigated using the acetic acid-induced writhing reflex, biphasic formalin-induced flinching behaviour and supraspinal hot plate-evoked nociception in mice. Carrageenan-induced rat paw oedema test was used to evaluate the anti-inflammatory action of CC in rats. Possible mechanism of antinociception and anti-inflammatory actions were examined using both in vivo model and molecular docking procedures against µ-opioid receptor (MOR), cyclooxygenase-2 (COX-2) and phospholipase A2 (PLA2) proteins, respectively. Results: The chromatographic procedure qualitatively and quantitatively confirmed the presence of rutin, quercetin, gallic acid, luteolin, pinostrobin, BiochaninA, formononetin and apigenin in CC. The in vivo nociceptive assay, showed that CC (50, 100, or 200 mg/kg, p.o.) significantly decreased mean number of writhing reflex with peak effect at 50 mg/kg (72% inhibition) when compared with vehicle control in mouse writhing test. Similarly, the biphasic formalin-induced nociception was significantly reduced by CC (50 mg/kg) with 24.61 and 66.73% inhibition of nociceptive reactions in both the early and late phases of formalin-induced inflammatory pain, respectively. In addition, CC significantly increased supraspinal thermally mediated pain threshold with maximum possible effects of 42.25 and 52.16% at CC 50 and 100 mg/kg, respectively, in hot-plate test. Similarly, CC100mg/kg caused time course inhibition of carrageenan-induced paw oedema in rat with peak effect (65.78%, CC 100 mg/kg; 6 h). Interestingly, the antinociceptive action of CC was blocked by the pre-treatment of mice with l-NG-nitro arginine methyl ester (L-NAME) or naloxone. The molecular docking analysis revealed prominent interactions of pinostrobin, physcion and lupeol with MOR, COX-2, and PLA2, respectively. Conclusion: Findings from this study showed that Cajanus cajan seeds extract possesses anti-nociceptive and anti-inflammatory through inhibition of inflammatory mediators (PLA2/COX-2) and activation of opioidergic signalling.
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- 2023
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28. Forecasting stock prices with commodity prices: New evidence from Feasible Quasi Generalized Least Squares (FQGLS) with non-linearities
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Fasanya, Ismail O., Adekoya, Oluwasegun, and Sonola, Ridwan
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- 2023
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29. Fe and Au-codoping of molybdenum carbide (MoC) nanosheet for hydrogen adsorption
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Louis, Hitler, Usun, Benita J., Agwamba, Ernest C., Amodu, Ismail O., Eno, Ededet A., and Adeyinka, Adedapo S.
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- 2023
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30. Assessing the Performance of Al12N12 and Al12P12 Nanostructured Materials for Alkali Metal Ion (Li, Na, K) Batteries
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Hitler Louis, Ernest E. Ekereke, Bartholomew B. Isang, Alexander I. Ikeuba, Ismail O. Amodu, Terkumbur E. Gber, Aniekan E. Owen, Adedapo S. Adeyinka, and Ernest C. Agwamba
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Chemistry ,QD1-999 - Published
- 2022
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31. Design of new bithieno thiophene (BTTI) central core-based small molecules as efficient hole transport materials for perovskite solar cells and donor materials for organic solar cells
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Abbas, Faheem, Mohammadi, Mohsen D., Louis, Hitler, Amodu, Ismail O., Charlie, Destiny E., and Gber, Terkumbur E.
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- 2023
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32. Uncertainty due to infectious diseases and bitcoin-gold nexus: Evidence from a non-parametric causality-in-quantiles approach
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Fasanya, Ismail O., Oyewole, Oluwatomisin, and Dauda, Mariam
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- 2023
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33. Antidepressant- and anxiolytic-like actions of Cajanus cajan seed extract mediated through monoaminergic, nitric oxide-cyclic GMP and GABAergic pathways
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Olubodun-Obadun, Taiwo G., Ishola, Ismail O., Adesokan, Timisola P., Anih, Blessing O., and Adeyemi, Olufunmilayo O.
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- 2023
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34. Sensor behavior of transition-metals (X = Ag, Au, Pd, and Pt) doped Zn11-X-O12 nanostructured materials for the detection of serotonin
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Louis, Hitler, Patrick, Mary, Amodu, Ismail O., Benjamin, Innocent, Ikot, Immaculata J., Iniama, Grace E., and Adeyinka, Adedapo S.
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- 2023
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35. Crystal structure analysis, magnetic measurement, DFT studies, and adsorption properties of novel 1-(2,5-dimethyphenyl)piperazine tetrachlorocobaltate hydrate
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Gharbi, Chaima, Louis, Hitler, Amodu, Ismail O., Benjamin, Innocent, Fujita, Wataru, Ben Nasr, Chérif, and Khedhiri, Lamia
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- 2023
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36. Halides (Cl, F, and Br) encapsulated Ga12As12 nanocages used to improve the cell voltage for enhanced battery performance
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Mohammadi, Mohsen Doust, Abbas, Faheem, Louis, Hitler, and Amodu, Ismail O.
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- 2023
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37. Trapping of dichlorosilane (H2SiCl2) gas by transition metals doped fullerene nanostructured materials
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Ntui, Tabe N., Louis, Hitler, Isang, Bartholomew B., Imojara, Anna, Amodu, Ismail O., Benjamin, Innocent, Akinterinwa, Ayodele, and Adeyinka, Adedapo S.
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- 2023
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38. On the connection between international REITs and oil markets: The role of economic policy uncertainty
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Fasanya, Ismail O. and Oyewole, Oluwatomisin J.
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- 2023
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39. Evaluation of Terminalia macroptera (Combretaceae) Guill. & Perr stem bark extract incorporated into an emulgel for the potential management of rheumatoid arthritis
- Author
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Kola-Mustapha, Adeola Tawakalitu, Taiwo, Suleiman Olubusayomi, Isiaka, Abimbola Rofiat, Amao, Sherifat Omowunmi, Ishola, Ismail O., Ghazali, Yusuf Oluwagbenga, and Usman, Sukurat O.
- Published
- 2023
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- View/download PDF
40. Output and price volatility spillovers among ECOWAS members: The role of global and regional uncertainties
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Dada, Matthew A., Oyewole, Oluwatomisin J., and Fasanya, Ismail O.
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- 2023
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41. A review on viscoelastic behaviour of plasticizers in ap/al/htpb based composite solid propellant
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Yaacob, I.N., Asli, A.F., Norkhairunnisa, M., Ahmad, K.A., Ismail, O., Salleh, N.A., and Shahedi, S.
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- 2023
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42. Probing the Reactions of Thiourea (CH4N2S) with Metals (X = Au, Hf, Hg, Ir, Os, W, Pt, and Re) Anchored on Fullerene Surfaces (C59X)
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Hitler Louis, Destiny E. Charlie, Ismail O. Amodu, Innocent Benjamin, Terkumbur E. Gber, Ernest C. Agwamba, and Adedapo S. Adeyinka
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Chemistry ,QD1-999 - Published
- 2022
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43. Dataset on biochemical inhibiting activities of selected phytochemicals in Azadirachta indica L as potential NS2B–NS3 proteases inhibitors
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Abel Kolawole Oyebamiji, Sunday A. Akintelu, Ismail O. Akande, Halleluyah O. Aworinde, Oluwafunmilola A. Adepegba, Emmanuel T. Akintayo, Cecillia O. Akintayo, Banjo Semire, and Jonathan O. Babalola
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Azadirachta indica L. ,NS2B–NS3 proteases ,Dengue ,Virus ,DFT ,Affinity ,Computer applications to medicine. Medical informatics ,R858-859.7 ,Science (General) ,Q1-390 - Abstract
The anti-NS2B–NS3 proteases activities of Azadirachta indica L. were investigated via the data obtained from selected bioactive compounds from Azadirachta indica L. The work was investigated using insilico approach and the series of computational software were used to execute the task. The software used were Spartan 14, material studio, Padel, Pymol, Autodock tool, Autodock vina and discovery studio. The obtained descriptors from 2D and 3D of the optimized compounds were screened and they were used to develop QSAR model using material studio software. Also, biological interaction between the selected bioactive compounds from Azadirachta indica L. and NS2B–NS3 proteases (PDB ID: 2fom) were accomplished using docking method and the calculated binding affinity as well as the residues involved in the interaction were reported. More so, the ADMET features for [(5S,6R,7S,8R,9S,10R,11S,12R,13S,17R)-17-(2,5-dihydroxy-2,5-dihydrofuran-3-yl)-11,12-dihydroxy-6‑methoxy-4,4,8,10,13-pentamethyl-1,16-dioxo-6,7,9,11,12,17-hexahydro-5H-cyclopenta[a]phenanthren-7-yl] 3-methylbut-2-enoate (Compound 6) and (10R,13S,14S,17S)-17-[1-(3,4-dihydroxy-5,5-dimethyloxolan-2-yl)ethyl]-4,4,10,13,14-pentamethyl-1,2,5,6,9,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-3-one (compound 12) with lowest binding affinity were investigated and reported.
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- 2023
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44. Technological progress in achieving environmental sustainability in Central and Southern Africa: The role of fossil fuels and institutional quality
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Okere, Kingsley I., primary and Fasanya, Ismail O., additional
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- 2024
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45. Formulation of Entandrophragma utile into an Herbal Emulgel for the Management of Inflammation
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Adeola Tawakalitu Kola-Mustapha, Haneefat Folashade Ibraheem, Suleiman Taiwo, Ismail O. Ishola, Sukurat Olasumbo Usman, and Yusuf Oluwagbenga Ghazali
- Subjects
inflammation ,herbal emulgel ,Entandrophragma utile ,Science ,Chemistry ,QD1-999 ,Inorganic chemistry ,QD146-197 ,General. Including alchemy ,QD1-65 - Abstract
Introduction: Globally, the incidence of inflammation and inflammatory disorders has continued to rise at an alarming rate. Entandrophragma utile is a species of flowering plant widely distributed in Africa and has been used for the management of sickle cell disease, rheumatism, ocular inflammation, duodenal and stomach ulcers. This research aims to formulate and evaluate an anti-inflammatory herbal emulgel using an extract from Entandrophragma utile stem bark (EUB). Method: Using a carrageenan-induced paw oedema model, the anti-inflammatory efficacy of EUB the extract was assessed. The formulated Entandrophragma utile emulgels (EUE) were characterized, and their anti-inflammatory activity was demonstrated, by utilizing diclofenac emulgel-treated rats with complete Freund’s adjuvant (CFA)-induced arthritis model as the positive control group. Results: The emulgels formulated had characterization results within acceptable ranges; pH (4.25–5.80), viscosity (418.9–112.8 mPas), spreadability (25.00–31.82 gcm/s), extrudability (30.86–51.02 g/cm2), and a swelling index of (30–60%). The emulgel produced a concentration-dependent inflammatory inhibition with a peak effect (117.97%) at the end of the 4th week which was comparable to that of commercial diclofenac (127.19%). The phytochemical analysis led to the identification of saponins, flavonoids, phenols, and tannins as active secondary metabolites. Conclusions: The stem bark extract of E. utile possessed noteworthy (p < 0.05) reduction in inflammation in comparison to diclofenac and its emulgel formulation showed enormous potential for treating inflammation and pain.
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- 2023
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46. Modeling of Re(I) tricarbonyl complexes against SARS-CoV-2 receptor via DFT, in-silico molecular docking, and QSAR
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Eno, Ededet A., Louis, Hitler, Unimuke, Tomsmith O., Gber, Terkumbur E., Akpanke, Josephat A., Amodu, Ismail O., Manicum, Amanda-Lee E., and Offiong, Offiong E.
- Published
- 2022
- Full Text
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47. Investors' sentiments and the dynamic connectedness between cryptocurrency and precious metals markets
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Fasanya, Ismail O., Oyewole, Oluwatomisin J., and Oliyide, Johnson A.
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- 2022
- Full Text
- View/download PDF
48. Monoaminergic system involvement in the antidepressant-like and anxiolytic-like properties of novel β-dihydroagarofuran sesquiterpene alkaloid and triterpenes isolated from Gymnosporia heterophylla aerial parts in mice
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Ishola, Ismail O., Olubodun-Obadun, Taiwo G., Ochieng, Charles O., Nwajuwe, Mary C., Mukoro, Reign-el U., and Adeyemi, Olufunmilayo O.
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- 2022
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49. Macroeconomic risk factors and REITs returns predictability in African markets: Evidence from a new approach
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Fasanya, Ismail O. and Adekoya, Oluwasegun B.
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- 2022
- Full Text
- View/download PDF
50. Evaluation of Terminalia macroptera (Combretaceae) Guill. & Perr stem bark extract incorporated into an emulgel for the potential management of rheumatoid arthritis
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Adeola Tawakalitu Kola-Mustapha, Suleiman Olubusayomi Taiwo, Abimbola Rofiat Isiaka, Sherifat Omowunmi Amao, Ismail O. Ishola, Yusuf Oluwagbenga Ghazali, and Sukurat O. Usman
- Subjects
Herbal emulgel ,Terminalia macroptera ,Anti-inflammatory ,Rheumatoid arthritis ,Science - Abstract
Background: Rheumatoid Arthritis (RA) is a chronic disease which causes inflammation and damage to the joint. The goals of treatment are to stop inflammation, relieve symptoms, improve physical function and overall well-being. The purpose of this study was to evaluate Terminalia macroptera stem bark (TMB) ethanol extract and formulate it into an herbal emulgel (TME) for the potential management of RA. Methods: Phytochemical analysis and anti-inflammatory activity of TMB were first evaluated using standard analytical methods and complete Freund's adjuvant (CFA) induced arthritis model in rats respectively. Post-formulation, physical characterization of the carbopol 940 based herbal emulgels (TME) and the reduction in the induced rat paw sizes by the herbal emulgels were evaluated using diclofenac emulgel as the positive control. Results: Phytochemical screening revealed the presence of flavonoids, tannins, terpenoids, saponins, and alkaloids. Inflammatory activity of the extract gave the highest percentage inhibition with TMB (50 mg/kg). The formulated herbal emulgels had good spreadability, extrudability, pH ranging from 4.5±0.2 to 6.9±0.4 and viscosity ranging from 0.36 ± 0.20 to 8.37 ± 0.65 Pas at 6 rpm and 0.26 ± 0.01 to 10.67±0.96 Pas at 12 rpm. TME emulgel significantly (p
- Published
- 2023
- Full Text
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