31 results on '"Ismail, N. E."'
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2. The Influence of Pitch Factor in Reducing Computed Tomography Head Dose Exposure: Single–Centre Trials
- Author
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Ismail, N. E., primary, Mahmood, F., additional, and Karim, M. K. A., additional
- Published
- 2018
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3. Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the global burden of disease study 2020, release 1
- Author
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Galles N. C., Liu P. Y., Updike R. L., Fullman N., Nguyen J., Rolfe S., Sbarra A. N., Schipp M. F., Marks A., Abady G. G., Abbas K. M., Abbasi S. W., Abbastabar H., Abd-Allah F., Abdoli A., Abolhassani H., Abosetugn A. E., Adabi M., Adamu A. A., Adetokunboh O. O., Adnani Q. E. S., Advani S. M., Afzal S., Aghamir S. M. K., Ahinkorah B. O., Ahmad S., Ahmad T., Ahmadi S., Ahmed H., Ahmed M. B., Ahmed Rashid T., Ahmed Salih Y., Akalu Y., Aklilu A., Akunna C. J., Al Hamad H., Alahdab F., Albano L., Alemayehu Y., Alene K. A., Al-Eyadhy A., Alhassan R. K., Ali L., Aljunid S. M., Almustanyir S., Altirkawi K. A., Alvis-Guzman N., Amu H., Andrei C. L., Andrei T., Ansar A., Ansari-Moghaddam A., Antonazzo I. C., Antony B., Arabloo J., Arab-Zozani M., Artanti K. D., Arulappan J., Awan A. T., Awoke M. A., Ayza M. A., Azarian G., Azzam A. Y., B D. B., Babar Z. -U. -D., Balakrishnan S., Banach M., Bante S. A., Barnighausen T. W., Barqawi H. J., Barrow A., Bassat Q., Bayarmagnai N., Bejarano Ramirez D. F., Bekuma T. T., Belay H. G., Belgaumi U. I., Bhagavathula A. S., Bhandari D., Bhardwaj N., Bhardwaj P., Bhaskar S., Bhattacharyya K., Bibi S., Bijani A., Biondi A., Boloor A., Braithwaite D., Buonsenso D., Butt Z. A., Camargos P., Carreras G., Carvalho F., Castaneda-Orjuela C. A., Chakinala R. C., Charan J., Chatterjee S., Chattu S. K., Chattu V. K., Chowdhury F. R., Christopher D. J., Chu D. -T., Chung S. -C., Cortesi P. A., Costa V. M., Couto R. A. S., Dadras O., Dagnew A. B., Dagnew B., Dai X., Dandona L., Dandona R., De Neve J. -W., Derbew Molla M., Derseh B. T., Desai R., Desta A. A., Dhamnetiya D., Dhimal M. L., Dhimal M., Dianatinasab M., Diaz D., Djalalinia S., Dorostkar F., Edem B., Edinur H. A., Eftekharzadeh S., El Sayed I., El Sayed Zaki M., Elhadi M., El-Jaafary S. I., Elsharkawy A., Enany S., Erkhembayar R., Esezobor C. I., Eskandarieh S., Ezeonwumelu I. J., Ezzikouri S., Fares J., Faris P. S., Feleke B. E., Ferede T. Y., Fernandes E., Fernandes J. C., Ferrara P., Filip I., Fischer F., Francis M. R., Fukumoto T., Gad M. M., Gaidhane S., Gallus S., Garg T., Geberemariyam B. S., Gebre T., Gebregiorgis B. G., Gebremedhin K. B., Gebremichael B., Gessner B. D., Ghadiri K., Ghafourifard M., Ghashghaee A., Gilani S. A., Glavan I. -R., Glushkova E. V., Golechha M., Gonfa K. B., Gopalani S. V., Goudarzi H., Gubari M. I. M., Guo Y., Gupta V. B., Gupta V. K., Gutierrez R. A., Haeuser E., Halwani R., Hamidi S., Hanif A., Haque S., Harapan H., Hargono A., Hashi A., Hassan S., Hassanein M. H., Hassanipour S., Hassankhani H., Hay S. I., Hayat K., Hegazy M. I., Heidari G., Hezam K., Holla R., Hoque M. E., Hosseini M., Hosseinzadeh M., Hostiuc M., Househ M., Hsieh V. C. -R., Huang J., Humayun A., Hussain R., Hussein N. R., Ibitoye S. E., Ilesanmi O. S., Ilic I. M., Ilic M. D., Inamdar S., Iqbal U., Irham L. M., Irvani S. S. N., Islam S. M. S., Ismail N. E., Itumalla R., Jha R. P., Joukar F., Kabir A., Kabir Z., Kalhor R., Kamal Z., Kamande S. M., Kandel H., Karch A., Kassahun G., Kassebaum N. J., Katoto P. D., Kelkay B., Kengne A. P., Khader Y. S., Khajuria H., Khalil I. A., Khan E. A., Khan G., Khan J., Khan M., Khan M. A., Khang Y. -H., Khoja A. T., Khubchandani J., Kim G. R., Kim M. S., Kim Y. J., Kimokoti R. W., Kisa A., Kisa S., Korshunov V. A., Kosen S., Kuate Defo B., Kulkarni V., Kumar A., Kumar G. A., Kumar N., Kwarteng A., La Vecchia C., Lami F. H., Landires I., Lasrado S., Lassi Z. S., Lee H., Lee Y. Y., Levi M., Lewycka S., Li S., Liu X., Lobo S. W., Lopukhov P. D., Lozano R., Lutzky Saute R., Magdy Abd El Razek M., Makki A., Malik A. A., Mansour-Ghanaei F., Mansournia M. A., Mantovani L. G., Martins-Melo F. R., Matthews P. C., Medina J. R. C., Mendoza W., Menezes R. G., Mengesha E. W., Meretoja T. J., Mersha A. G., Mesregah M. K., Mestrovic T., Miazgowski B., Milne G. J., Mirica A., Mirrakhimov E. M., Mirzaei H. R., Misra S., Mithra P., Moghadaszadeh M., Mohamed T. A., Mohammad K. A., Mohammad Y., Mohammadi M., Mohammadian-Hafshejani A., Mohammed A., Mohammed S., Mohapatra A., Mokdad A. H., Molokhia M., Monasta L., Moni M. A., Montasir A. A., Moore C. E., Moradi G., Moradzadeh R., Moraga P., Mueller U. O., Munro S. B., Naghavi M., Naimzada M. D., Naveed M., Nayak B. P., Negoi I., Neupane Kandel S., Nguyen T. H., Nikbakhsh R., Ningrum D. N. A., Nixon M. R., Nnaji C. A., Noubiap J. J., Nunez-Samudio V., Nwatah V. E., Oancea B., Ochir C., Ogbo F. A., Olagunju A. T., Olakunde B. O., Onwujekwe O. E., Otstavnov N., Otstavnov S. S., Owolabi M. O., Padubidri J. R., Pakshir K., Park E. -C., Pashazadeh Kan F., Pathak M., Paudel R., Pawar S., Pereira J., Peres M. F. P., Perianayagam A., Pinheiro M., Pirestani M., Podder V., Polibin R. V., Pollok R. C. G., Postma M. J., Pottoo F. H., Rabiee M., Rabiee N., Radfar A., Rafiei A., Rahimi-Movaghar V., Rahman M., Rahmani A. M., Rahmawaty S., Rajesh A., Ramshaw R. E., Ranasinghe P., Rao C. R., Rao S. J., Rathi P., Rawaf D. L., Rawaf S., Renzaho A. M. N., Rezaei N., Rezai M. S., Rios-Blancas M., Rogowski E. L. B., Ronfani L., Rwegerera G. M., Saad A. M., Sabour S., Saddik B., Saeb M. R., Saeed U., Sahebkar A., Sahraian M. A., Salam N., Salimzadeh H., Samaei M., Samy A. M., Sanabria J., Sanmarchi F., Santric-Milicevic M. M., Sartorius B., Sarveazad A., Sathian B., Sawhney M., Saxena D., Saxena S., Seidu A. -A., Seylani A., Shaikh M. A., Shamsizadeh M., Shetty P. H., Shigematsu M., Shin J. I., Sidemo N. B., Singh A., Singh J. A., Sinha S., Skryabin V. Y., Skryabina A. A., Soheili A., Tadesse E. G., Tamiru A. T., Tan K. -K., Tekalegn Y., Temsah M. -H., Thakur B., Thapar R., Thavamani A., Tobe-Gai R., Tohidinik H. R., Tovani-Palone M. R., Traini E., Tran B. X., Tripathi M., Tsegaye B., Tsegaye G. W., Ullah A., Ullah S., Unim B., Vacante M., Velazquez D. Z., Vo B., Vollmer S., Vu G. T., Vu L. G., Waheed Y., Winkler A. S., Wiysonge C. S., Yigit V., Yirdaw B. W., Yon D. K., Yonemoto N., Yu C., Yuce D., Yunusa I., Zamani M., Zamanian M., Zewdie D. T., Zhang Z. -J., Zhong C., Zumla A., Murray C. J. L., Lim S. S., Mosser J. F., Aghamir S., Sahraian M., Mansournia M., Mirzaei H., Temsah M., Andrei C., Glavan I., Antonazzo I., Singh Mtech A., Padubidri J., Babar Z., De Neve J., Noubiap J., Chakinala R., Chattu S., Chattu V., Chu D., Chung S., Kumar G., Gilani S., Gupta V., Hargono Dr A., Islam S., Hsieh V., Irvani S. N., Ismail N., Khang Y., Yon D., Kim G., Park E., Shin J., Kim M., Kim Y., Lee Y., Medina J. C., Naimzada M., Rahmani A., Rezai M., Rao S., Saeb M., Seidu A., Tan K., Tohidinik H., Zhang Z., Galles, N, Liu, P, Updike, R, Fullman, N, Nguyen, J, Rolfe, S, Sbarra, A, Schipp, M, Marks, A, Abady, G, Abbas, K, Abbasi, S, Abbastabar, H, Abd-Allah, F, Abdoli, A, Abolhassani, H, Abosetugn, A, Adabi, M, Adamu, A, Adetokunboh, O, Adnani, Q, Advani, S, Afzal, S, Aghamir, S, Ahinkorah, B, Ahmad, S, Ahmad, T, Ahmadi, S, Ahmed, H, Ahmed, M, Ahmed Rashid, T, Ahmed Salih, Y, Akalu, Y, Aklilu, A, Akunna, C, Al Hamad, H, Alahdab, F, Albano, L, Alemayehu, Y, Alene, K, Al-Eyadhy, A, Alhassan, R, Ali, L, Aljunid, S, Almustanyir, S, Altirkawi, K, Alvis-Guzman, N, Amu, H, Andrei, C, Andrei, T, Ansar, A, Ansari-Moghaddam, A, Antonazzo, I, Antony, B, Arabloo, J, Arab-Zozani, M, Artanti, K, Arulappan, J, Awan, A, Awoke, M, Ayza, M, Azarian, G, Azzam, A, B, D, Babar, Z, Balakrishnan, S, Banach, M, Bante, S, Barnighausen, T, Barqawi, H, Barrow, A, Bassat, Q, Bayarmagnai, N, Bejarano Ramirez, D, Bekuma, T, Belay, H, Belgaumi, U, Bhagavathula, A, Bhandari, D, Bhardwaj, N, Bhardwaj, P, Bhaskar, S, Bhattacharyya, K, Bibi, S, Bijani, A, Biondi, A, Boloor, A, Braithwaite, D, Buonsenso, D, Butt, Z, Camargos, P, Carreras, G, Carvalho, F, Castaneda-Orjuela, C, Chakinala, R, Charan, J, Chatterjee, S, Chattu, S, Chattu, V, Chowdhury, F, Christopher, D, Chu, D, Chung, S, Cortesi, P, Costa, V, Couto, R, Dadras, O, Dagnew, A, Dagnew, B, Dai, X, Dandona, L, Dandona, R, De Neve, J, Derbew Molla, M, Derseh, B, Desai, R, Desta, A, Dhamnetiya, D, Dhimal, M, Dianatinasab, M, Diaz, D, Djalalinia, S, Dorostkar, F, Edem, B, Edinur, H, Eftekharzadeh, S, El Sayed, I, El Sayed Zaki, M, Elhadi, M, El-Jaafary, S, Elsharkawy, A, Enany, S, Erkhembayar, R, Esezobor, C, Eskandarieh, S, Ezeonwumelu, I, Ezzikouri, S, Fares, J, Faris, P, Feleke, B, Ferede, T, Fernandes, E, Fernandes, J, Ferrara, P, Filip, I, Fischer, F, Francis, M, Fukumoto, T, Gad, M, Gaidhane, S, Gallus, S, Garg, T, Geberemariyam, B, Gebre, T, Gebregiorgis, B, Gebremedhin, K, Gebremichael, B, Gessner, B, Ghadiri, K, Ghafourifard, M, Ghashghaee, A, Gilani, S, Glavan, I, Glushkova, E, Golechha, M, Gonfa, K, Gopalani, S, Goudarzi, H, Gubari, M, Guo, Y, Gupta, V, Gutierrez, R, Haeuser, E, Halwani, R, Hamidi, S, Hanif, A, Haque, S, Harapan, H, Hargono, A, Hashi, A, Hassan, S, Hassanein, M, Hassanipour, S, Hassankhani, H, Hay, S, Hayat, K, Hegazy, M, Heidari, G, Hezam, K, Holla, R, Hoque, M, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Househ, M, Hsieh, V, Huang, J, Humayun, A, Hussain, R, Hussein, N, Ibitoye, S, Ilesanmi, O, Ilic, I, Ilic, M, Inamdar, S, Iqbal, U, Irham, L, Irvani, S, Islam, S, Ismail, N, Itumalla, R, Jha, R, Joukar, F, Kabir, A, Kabir, Z, Kalhor, R, Kamal, Z, Kamande, S, Kandel, H, Karch, A, Kassahun, G, Kassebaum, N, Katoto, P, Kelkay, B, Kengne, A, Khader, Y, Khajuria, H, Khalil, I, Khan, E, Khan, G, Khan, J, Khan, M, Khang, Y, Khoja, A, Khubchandani, J, Kim, G, Kim, M, Kim, Y, Kimokoti, R, Kisa, A, Kisa, S, Korshunov, V, Kosen, S, Kuate Defo, B, Kulkarni, V, Kumar, A, Kumar, G, Kumar, N, Kwarteng, A, La Vecchia, C, Lami, F, Landires, I, Lasrado, S, Lassi, Z, Lee, H, Lee, Y, Levi, M, Lewycka, S, Li, S, Liu, X, Lobo, S, Lopukhov, P, Lozano, R, Lutzky Saute, R, Magdy Abd El Razek, M, Makki, A, Malik, A, Mansour-Ghanaei, F, Mansournia, M, Mantovani, L, Martins-Melo, F, Matthews, P, Medina, J, Mendoza, W, Menezes, R, Mengesha, E, Meretoja, T, Mersha, A, Mesregah, M, Mestrovic, T, Miazgowski, B, Milne, G, Mirica, A, Mirrakhimov, E, Mirzaei, H, Misra, S, Mithra, P, Moghadaszadeh, M, Mohamed, T, Mohammad, K, Mohammad, Y, Mohammadi, M, Mohammadian-Hafshejani, A, Mohammed, A, Mohammed, S, Mohapatra, A, Mokdad, A, Molokhia, M, Monasta, L, Moni, M, Montasir, A, Moore, C, Moradi, G, Moradzadeh, R, Moraga, P, Mueller, U, Munro, S, Naghavi, M, Naimzada, M, Naveed, M, Nayak, B, Negoi, I, Neupane Kandel, S, Nguyen, T, Nikbakhsh, R, Ningrum, D, Nixon, M, Nnaji, C, Noubiap, J, Nunez-Samudio, V, Nwatah, V, Oancea, B, Ochir, C, Ogbo, F, Olagunju, A, Olakunde, B, Onwujekwe, O, Otstavnov, N, Otstavnov, S, Owolabi, M, Padubidri, J, Pakshir, K, Park, E, Pashazadeh Kan, F, Pathak, M, Paudel, R, Pawar, S, Pereira, J, Peres, M, Perianayagam, A, Pinheiro, M, Pirestani, M, Podder, V, Polibin, R, Pollok, R, Postma, M, Pottoo, F, Rabiee, M, Rabiee, N, Radfar, A, Rafiei, A, Rahimi-Movaghar, V, Rahman, M, Rahmani, A, Rahmawaty, S, Rajesh, A, Ramshaw, R, Ranasinghe, P, Rao, C, Rao, S, Rathi, P, Rawaf, D, Rawaf, S, Renzaho, A, Rezaei, N, Rezai, M, Rios-Blancas, M, Rogowski, E, Ronfani, L, Rwegerera, G, Saad, A, Sabour, S, Saddik, B, Saeb, M, Saeed, U, Sahebkar, A, Sahraian, M, Salam, N, Salimzadeh, H, Samaei, M, Samy, A, Sanabria, J, Sanmarchi, F, Santric-Milicevic, M, Sartorius, B, Sarveazad, A, Sathian, B, Sawhney, M, Saxena, D, Saxena, S, Seidu, A, Seylani, A, Shaikh, M, Shamsizadeh, M, Shetty, P, Shigematsu, M, Shin, J, Sidemo, N, Singh, A, Singh, J, Sinha, S, Skryabin, V, Skryabina, A, Soheili, A, Tadesse, E, Tamiru, A, Tan, K, Tekalegn, Y, Temsah, M, Thakur, B, Thapar, R, Thavamani, A, Tobe-Gai, R, Tohidinik, H, Tovani-Palone, M, Traini, E, Tran, B, Tripathi, M, Tsegaye, B, Tsegaye, G, Ullah, A, Ullah, S, Unim, B, Vacante, M, Velazquez, D, Vo, B, Vollmer, S, Vu, G, Vu, L, Waheed, Y, Winkler, A, Wiysonge, C, Yigit, V, Yirdaw, B, Yon, D, Yonemoto, N, Yu, C, Yuce, D, Yunusa, I, Zamani, M, Zamanian, M, Zewdie, D, Zhang, Z, Zhong, C, Zumla, A, Murray, C, Lim, S, Mosser, J, Singh Mtech, A, Hargono Dr, A, Value, Affordability and Sustainability (VALUE), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Microbes in Health and Disease (MHD), Tampere University, Health Sciences, HUS Comprehensive Cancer Center, University of Helsinki, Helsinki University Hospital Area, Abbas, Kaja [0000-0003-0563-1576], Veritati - Repositório Institucional da Universidade Católica Portuguesa, and GBD 2020, Release 1, Vaccine Coverage Collaborators
- Subjects
Vaccine coverage ,Vacunación de rutina ,Time Factors ,Vaccination Coverage ,Global Plan of Action on Vaccines ,Service delivery framework ,IMPACT ,Global Health ,Cobertura de vacunas ,Routine childhood vaccination ,Global Burden of Disease ,Public Health ,Underserved Population ,Polio vaccine ,0302 clinical medicine ,WORLDWIDE ,Routine immunisation ,Global health ,Medicine ,030212 general & internal medicine ,Child ,11 Medical and Health Sciences ,General Medicine ,Articles ,childhood vaccination, GBD ,Plan de Acción Mundial sobre Vacunas ,3142 Public health care science, environmental and occupational health ,3. Good health ,ddc ,Vaccination ,Poliovirus Vaccines ,Action plan ,Life Sciences & Biomedicine ,Vacunación infantil ,MED/42 - IGIENE GENERALE E APPLICATA ,030231 tropical medicine ,Measles Vaccine ,03 medical and health sciences ,Medicine, General & Internal ,Environmental health ,General & Internal Medicine ,Humans ,IMMUNIZATION COVERAGE ,VALIDITY ,Vaccination approaches ,PROGRESS ,Diphtheria-Tetanus-Pertussis Vaccine ,CONFLICT ,Equity (economics) ,Science & Technology ,business.industry ,MORTALITY ,GBD 2020, Release 1, Vaccine Coverage Collaborators ,Global burden of disease, injury and risk factors ,Child vaccination ,Global vaccine policies ,Políticas mundiales de vacunación ,Carga global de enfermedades, lesiones y factores de riesgo ,Global vaccination policies ,3121 General medicine, internal medicine and other clinical medicine ,Childhood vaccination ,Measles vaccine ,Routine vaccination ,business ,Vaccine programme implementation - Abstract
Medir la vacunación infantil de rutina es crucial para informar las políticas mundiales de vacunación y la implementación de programas, y para hacer un seguimiento del progreso hacia los objetivos establecidos por el Plan de Acción Mundial sobre Vacunas (GVAP) y la Agenda de Inmunización 2030. Se necesitan estimaciones sólidas de la cobertura de vacunación de rutina para identificar los éxitos pasados y persistentes. vulnerabilidades. A partir del Estudio de la carga global de enfermedades, lesiones y factores de riesgo (GBD) 2020, versión 1, realizamos un análisis sistemático de las tendencias de cobertura de vacunas a nivel mundial, regional y nacional utilizando un marco estadístico, por vacuna y a lo largo del tiempo. Métodos Para este análisis recopilamos 55 326 observaciones específicas del país, de la cohorte, del año, de la vacuna y de la dosis de la cobertura de vacunación infantil de rutina entre 1980 y 2019. Utilizando el proceso de regresión gaussiana espaciotemporal, Estimaciones específicas por año de 11 indicadores de cobertura de vacunación infantil de rutina para 204 países y territorios desde 1980 hasta 2019, ajustando los sesgos en los datos informados por los países y reflejando los desabastecimientos informados y las interrupciones en el suministro. Analizamos las tendencias mundiales y regionales en la cobertura y el número de niños con dosis cero (definidos como aquellos que nunca recibieron una dosis de vacuna contra la difteria, el tétanos y la tos ferina [DTP]), el progreso hacia los objetivos del GVAP y la relación entre la cobertura de la vacuna y el desarrollo sociodemográfico. Recomendaciones Para 2019, la cobertura mundial de la tercera dosis de DTP (DTP3; 81,6 % [intervalo de incertidumbre del 95 % 80,4–82,7]) se duplicó con creces con respecto a los niveles estimados en 1980 (39,9 % [37,5–42 ·1]), al igual que la cobertura mundial de la vacuna antisarampionosa de primera dosis (MCV1; del 38,5 % [35,4–41,3] en 1980 al 83,6 % [82,3–84,8 ] en 2019). La cobertura de la vacuna antipoliomielítica de tercera dosis (Pol3) también aumentó, del 42,6 % (41,4–44,1) en 1980 al 79,8 % (78,4–81,1) en 2019, y la cobertura mundial de vacunas más nuevas Las vacunas aumentaron rápidamente entre 2000 y 2019. La cantidad mundial de niños que recibieron dosis cero se redujo en casi un 75 % entre 1980 y 2019, de 56,8 millones (52,6–60,9) a 14,5 millones (13,4– 15·9). Sin embargo, durante la última década, la cobertura mundial de vacunas se estabilizó en general; 94 países y territorios registraron una disminución de la cobertura de DTP3 desde 2010. Se estimó que solo 11 países y territorios alcanzaron el objetivo nacional del GVAP de al menos una cobertura del 90 % para todas las vacunas evaluadas en 2019. Interpretación Después de lograr grandes avances en la cobertura de vacunación infantil en todo el mundo, en gran parte del mundo este progreso se estancó o se revirtió de 2010 a 2019. Estos hallazgos subrayan la importancia de revisar las estrategias de inmunización de rutina y los enfoques programáticos, centrando la prestación de servicios en torno a la equidad y las poblaciones desatendidas. Fortalecer los datos de vacunas y los sistemas de monitoreo es crucial para estas actividades, ahora y hasta 2030, para garantizar que todos los niños tengan acceso y puedan beneficiarse de las vacunas que salvan vidas. Measuring routine childhood vaccination is crucial to inform global vaccine policies and programme implementation, and to track progress towards targets set by the Global Vaccine Action Plan (GVAP) and Immunization Agenda 2030. Robust estimates of routine vaccine coverage are needed to identify past successes and persistent vulnerabilities. Drawing from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020, Release 1, we did a systematic analysis of global, regional, and national vaccine coverage trends using a statistical framework, by vaccine and over time. Methods For this analysis we collated 55 326 country-specific, cohort-specific, year-specific, vaccine-specific, and dose-specific observations of routine childhood vaccination coverage between 1980 and 2019. Using spatiotemporal Gaussian process regression, we produced location-specific and year-specific estimates of 11 routine childhood vaccine coverage indicators for 204 countries and territories from 1980 to 2019, adjusting for biases in country-reported data and reflecting reported stockouts and supply disruptions. We analysed global and regional trends in coverage and numbers of zero-dose children (defined as those who never received a diphtheria-tetanus-pertussis [DTP] vaccine dose), progress towards GVAP targets, and the relationship between vaccine coverage and sociodemographic development. Findings By 2019, global coverage of third-dose DTP (DTP3; 81·6% [95% uncertainty interval 80·4–82·7]) more than doubled from levels estimated in 1980 (39·9% [37·5–42·1]), as did global coverage of the first-dose measles-containing vaccine (MCV1; from 38·5% [35·4–41·3] in 1980 to 83·6% [82·3–84·8] in 2019). Third-dose polio vaccine (Pol3) coverage also increased, from 42·6% (41·4–44·1) in 1980 to 79·8% (78·4–81·1) in 2019, and global coverage of newer vaccines increased rapidly between 2000 and 2019. The global number of zero-dose children fell by nearly 75% between 1980 and 2019, from 56·8 million (52·6–60·9) to 14·5 million (13·4–15·9). However, over the past decade, global vaccine coverage broadly plateaued; 94 countries and territories recorded decreasing DTP3 coverage since 2010. Only 11 countries and territories were estimated to have reached the national GVAP target of at least 90% coverage for all assessed vaccines in 2019. Interpretation After achieving large gains in childhood vaccine coverage worldwide, in much of the world this progress was stalled or reversed from 2010 to 2019. These findings underscore the importance of revisiting routine immunisation strategies and programmatic approaches, recentring service delivery around equity and underserved populations. Strengthening vaccine data and monitoring systems is crucial to these pursuits, now and through to 2030, to ensure that all children have access to, and can benefit from, lifesaving vaccines.
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- 2021
4. Assessing performance of the Healthcare Access and Quality Index, overall and by select age groups, for 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019
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Lozano, R., Haakenstad, A., Yearwood, J. A., Fullman, N., Bintz, C., Bienhoff, K., Weaver, M. R., Nandakumar, V., Joffe, J. N., LeGrand, K. E., Knight, M., Abbafati, C., Abbasi-Kangevari, M., Abdoli, A., Zuniga, R. A. A., Adedeji, I. A., Adekanmbi, V., Adetokunboh, O. O., Afzal, M. S., Afzal, S., Agudelo-Botero, M., Ahinkorah, B. O., Ahmad, S., Ahmadi, A., Ahmadi, S., Ahmed, A., Rashid, T. A., Aji, B., Akande-Sholabi, W., Alam, K., Al Hamad, H., Alhassan, R. K., Ali, L., Alipour, V., Aljunid, S. M., Ameyaw, E. K., Amin, T. T., Amu, H., Amugsi, D. A., Ancuceanu, R., Andrade, P. P., Anjum, A., Arabloo, J., Arab-Zozani, M., Ariffin, H., Arulappan, J., Aryan, Z., Ashraf, T., Atnafu, D. D., Atreya, A., Ausloos, M., Avila-Burgos, L., Ayano, G., Ayanore, M. A., Azari, S., Badiye, A. D., Baig, A. A., Bairwa, M., Bakkannavar, S. M., Baliga, S., Banik, P. C., Barnighausen, T. W., Barra, F., Barrow, A., Basu, S., Bayati, M., Belete, R., Bell, A. W., Bhagat, D. S., Bhagavathula, A. S., Bhardwaj, P., Bhardwaj, N., Bhaskar, S., Bhattacharyya, K., Bhutta, Z. A., Bibi, S., Bijani, A., Bikbov, B., Biondi, A., Bolarinwa, O. A., Bonny, A., Brenner, H., Buonsenso, D., Burkart, K., Busse, R., Butt, Z. A., Butt, N. S., dos Santos, F. L. C., Cahuana Hurtado, Lucero, Camera, Luis Alberto, Cardenas, R., Carneiro, V. L. A., Catala-Lopez, F., Chandan, J. S., Charan, J., Chavan, P. P., Chen, S. M., Chen, S., Choudhari, S. G., Chowdhury, E. K., Chowdhury, M. A. K., Cirillo, M., Corso, B., Dadras, O., Dahlawi, S. M. A., Dai, X. C., Dandona, L., Dandona, R., Dangel, W. J., Davila-Cervantes, C. A., Davletov, K., Deuba, K., Dhimal, M., Dhimal, M. L., Djalalinia, S., Do, H. P., Doshmangir, L., Duncan, B. B., Effiong, A., Ehsani-Chimeh, E., Elgendy, I. Y., Elhadi, M., El Sayed, I., El Tantawi, M., Erku, D. A., Eskandarieh, S., Fares, J., Farzadfar, F., Ferrero, S., Desideri, L. F., Fischer, F., Foigt, N. A., Foroutan, M., Fukumoto, T., Gaal, P. A., Gaihre, S., Gardner, W. M., Garg, T., Obsa, A. G., Ghafourifard, M., Ghashghaee, A., Ghith, N., Gilani, S. A., Gill, P. S., Goharinezhad, S., Golechha, M., Guadamuz, J. S., Guo, Y. M., Das Gupta, R., Gupta, R., Gupta, V. K., Gupta, V. B., Hamiduzzaman, M., Hanif, A., Haro, J. M., Hasaballah, A. I., Hasan, M. M., Hasan, M. T., Hashi, A., Hay, S. I., Hayat, K., Heidari, M., Heidari, G., Henry, N. J., Herteliu, C., Holla, R., Hossain, S., Hossain, S. J., Hossain, M. B. H., Hosseinzadeh, M., Hostiuc, S., Hoveidamanesh, S., Hsieh, V. C. R., Hu, G. Q., Huang, J. J., Huda, M. M., Ifeagwu, S. C., Ikuta, K. S., Ilesanmi, O. S., Irvani, S. S. N., Islam, R. M., Islam, S. M. S., Ismail, N. E., Iso, H., Isola, G., Itumalla, R., Iwagami, M., Jahani, M. A., Jahanmehr, N., Jain, R., Jakovljevic, M., Janodia, M. D., Jayapal, S. K., Jayaram, S., Jha, R. P., Jonas, J. B., Joo, T., Joseph, N., Jurisson, M., Kabir, A., Kalankesh, L. R., Kalhor, R., Kamath, A. M., Kamenov, K., Kandel, H., Kantar, R. S., Kapoor, N., Karanikolos, M., Katikireddi, S. V., Kavetskyy, T., Kawakami, N., Kayode, G. A., Keikavoosi-Arani, L., Keykhaei, M., Khader, Y. S., Khajuria, H., Khalilov, R., Khammarnia, M., Khan, M. N., Khan, M. A. B., Khan, M., Khezeli, M., Kim, M. S., Kim, Y. J., Kisa, S., Kisa, A., Klymchuk, V., Koly, K. N., Korzh, O., Kosen, S., Koul, P. A., Defo, B. K., Kumar, G. A., Kusuma, D., Kyu, H. H., Larsson, A. O., Lasrado, S., Lee, W. C., Lee, Y. H., Lee, C. B., Li, S. S., Lucchetti, G., Mahajan, P. B., Majeed, A., Makki, A., Malekzadeh, R., Malik, A. A., Malta, D. C., Mansournia, M. A., Mantovani, L. G., Martinez-Valle, A., Martins-Melo, F. R., Masoumi, S. Z., Mathur, M. R., Maude, R. J., Maulik, P. K., McKee, M., Mendoza, W., Menezes, R. G., Mensah, G. A., Meretoja, A., Meretoja, T. J., Mestrovic, T., Michalek, I. M., Mirrakhimov, E. M., Misganaw, A., Misra, S., Moazen, B., Mohammadi, M., Mohammed, S., Moitra, M., Mokdad, A. H., Molokhia, M., Monasta, L., Moni, M. A., Moradi, G., Moreira, R. S., Mosser, J. F., Mostafavi, E., Mouodi, S., Nagarajan, A. J., Nagata, C., Naghavi, M., Nangia, V., Swamy, S. N., Narayana, A. I., Nascimento, B. R., Nassereldine, H., Nayak, B. P., Nazari, J., Negoi, I., Nepal, S., Kandel, S. N., Ngunjiri, J. W., Nguyen, H. L. T, Nguyen, C. T., Ningrum, D. N. A., Noubiap, J. J., Oancea, B., Oghenetega, O. B., Oh, I. H., Olagunju, A. T., Olakunde, B. O., Bali, A. O., Omer, E., Onwujekwe, O. E., Otoiu, A., Padubidri, J. R., Palladino, R., Pana, A., Panda-Jonas, S., Pandi-Perumal, S. R., Pardhan, S., Pasupula, D. K., Pathak, P. K., Patton, G. C., Pawar, S., Pereira, J., Pilania, M., Piroozi, B., Podder, V., Pokhrel, K. N., Postma, M. J., Prada, S. I., Syed, Z. Q., Rabiee, N., Radhakrishnan, R. A., Rahman, M. M., Rahman, M., Rahman, M. H. U., Rahmani, A. M., Ranabhat, C. L., Rao, C. R., Rao, S. J., Rasella, D., Rawaf, S., Rawaf, D. L., Rawal, L., Renzaho, A. M. N., Reshmi, B., Resnikoff, S., Rezapour, A., Riahi, S. M., Ripon, R. K., Sacco, S., Sadeghi, M., Saeed, U., Sahebkar, A., Sahiledengle, B., Sahoo, H., Sahu, M., Salama, J. S., Salamati, P., Samy, A. M., Sanabria, J., Santric-Milicevic, M. M., Sathian, B., Sawhney, M., Schmidt, M. I., Seidu, A. A., Sepanlou, S. G., Seylani, A., Shaikh, M. A., Sheikh, A., Shetty, A., Shigematsu, M., Shiri, R., Shivakumar, K. M., Shokri, A., Singh, J. A., Sinha, D. N., Skryabin, V. Y., Skryabina, A. A., Sofi-Mahmudi, A., Sousa, R. A. R. C., Stephens, J. H., Sun, J., Szocska, M., Tabares-Seisdedos, R., Tadbiri, H., Tamiru, A. T., Thankappan, K. R., Topor-Madry, R., Tovani-Palone, M. R., Tran, M. T. N., Tran, B. X., Tripathi, N., Tripathy, J. P., Troeger, C. E., Uezono, D. R., Ullah, S., Ullah, A., Unnikrishnan, B., Vacante, M., Tahbaz, S. V., Valdez, P. R., Vasic, M., Veroux, M., Vervoort, D., Violante, F. S., Vladimirov, S. K., Vlassov, V., Vo, B., Waheed, Y., Wamai, R. G., Wang, Y. P., Wang, Y. Z., Ward, P., Wiangkham, T., Yadav, L., Jabbari, S. H. Y., Yamagishi, K., Yaya, S., Yazdi-Feyzabadi, V., Yi, S. Y., Yigit, V., Yonemoto, N., Younis, M. Z., Yu, C. H., Yunusa, I., Bin Zaman, S., Zastrozhin, M. S., Zhang, Z. J., Zhong, C. W., Zuniga, Y. M. H., Lim, S. S., Murray, C. J. L., GBD 2019 Healthcare Access Quality, Clinicum, Department of Neurosciences, HUS Comprehensive Cancer Center, Haakenstad, Annie, Yearwood, Jamal Akeem, Fullman, Nancy, Bintz, Corinne, Bienhoff, Kelly, Weaver, Marcia R, Nandakumar, Vishnu, Joffe, Jonah N, Legrand, Kate E, Knight, Megan, Abbafati, Cristiana, Abbasi-Kangevari, Mohsen, Abdoli, Amir, Abeldaño Zuñiga, Roberto Ariel, Adedeji, Isaac Akinkunmi, Adekanmbi, Victor, Adetokunboh, Olatunji O, Afzal, Muhammad Sohail, Afzal, Saira, Agudelo-Botero, Marcela, Ahinkorah, Bright Opoku, Ahmad, Sajjad, Ahmadi, Ali, Ahmadi, Sepideh, Ahmed, Ali, Ahmed Rashid, Tarik, Aji, Budi, Akande-Sholabi, Wuraola, Alam, Khurshid, Al Hamad, Hanadi, Alhassan, Robert Kaba, Ali, Liaqat, Alipour, Vahid, Aljunid, Syed Mohamed, Ameyaw, Edward Kwabena, Amin, Tarek Tawfik, Amu, Hubert, Amugsi, Dickson A, Ancuceanu, Robert, Andrade, Pedro Prata, Anjum, Afifa, Arabloo, Jalal, Arab-Zozani, Morteza, Ariffin, Hany, Arulappan, Judie, Aryan, Zahra, Ashraf, Tahira, Atnafu, Desta Debalkie, Atreya, Alok, Ausloos, Marcel, Avila-Burgos, Leticia, Ayano, Getinet, Ayanore, Martin Amogre, Azari, Samad, Badiye, Ashish D, Baig, Atif Amin, Bairwa, Mohan, Bakkannavar, Shankar M, Baliga, Shrikala, Banik, Palash Chandra, Bärnighausen, Till Winfried, Barra, Fabio, Barrow, Amadou, Basu, Sanjay, Bayati, Mohsen, Belete, Rebuma, Bell, Arielle Wilder, Bhagat, Devidas S, Bhagavathula, Akshaya Srikanth, Bhardwaj, Pankaj, Bhardwaj, Nikha, Bhaskar, Sonu, Bhattacharyya, Krittika, Bhutta, Zulfiqar A, Bibi, Sadia, Bijani, Ali, Bikbov, Bori, Biondi, Antonio, Bolarinwa, Obasanjo Afolabi, Bonny, Aime, Brenner, Hermann, Buonsenso, Danilo, Burkart, Katrin, Busse, Reinhard, Butt, Zahid A, Butt, Nadeem Shafique, Caetano dos Santos, Florentino Luciano, Cahuana-Hurtado, Lucero, Cámera, Luis Alberto, Cárdenas, Rosario, Carneiro, Vera L A, Catalá-López, Ferrán, Chandan, Joht Singh, Charan, Jaykaran, Chavan, Prachi P, Chen, Simiao, Chen, Shu, Choudhari, Sonali Gajanan, Chowdhury, Enayet Karim, Chowdhury, Mohiuddin Ahsanul Kabir, Cirillo, Massimo, Corso, Barbara, Dadras, Omid, Dahlawi, Saad M A, Dai, Xiaochen, Dandona, Lalit, Dandona, Rakhi, Dangel, William Jame, Dávila-Cervantes, Claudio Alberto, Davletov, Kairat, Deuba, Keshab, Dhimal, Meghnath, Dhimal, Mandira Lamichhane, Djalalinia, Shirin, Do, Huyen Phuc, Doshmangir, Leila, Duncan, Bruce B, Effiong, Andem, Ehsani-Chimeh, Elham, Elgendy, Islam Y, Elhadi, Muhammed, El Sayed, Iman, El Tantawi, Maha, Erku, Daniel Asfaw, Eskandarieh, Sharareh, Fares, Jawad, Farzadfar, Farshad, Ferrero, Simone, Ferro Desideri, Lorenzo, Fischer, Florian, Foigt, Nataliya A, Foroutan, Masoud, Fukumoto, Takeshi, Gaal, Peter Andra, Gaihre, Santosh, Gardner, William M, Garg, Tushar, Getachew Obsa, Abera, Ghafourifard, Mansour, Ghashghaee, Ahmad, Ghith, Nermin, Gilani, Syed Amir, Gill, Paramjit Singh, Goharinezhad, Salime, Golechha, Mahaveer, Guadamuz, Jenny S, Guo, Yuming, Gupta, Rajat Da, Gupta, Rajeev, Gupta, Vivek Kumar, Gupta, Veer Bala, Hamiduzzaman, Mohammad, Hanif, Asif, Haro, Josep Maria, Hasaballah, Ahmed I, Hasan, Md Mehedi, Hasan, M Tasdik, Hashi, Abdiwahab, Hay, Simon I, Hayat, Khezar, Heidari, Mohammad, Heidari, Golnaz, Henry, Nathaniel J, Herteliu, Claudiu, Holla, Ramesh, Hossain, Sahadat, Hossain, Sheikh Jamal, Hossain, Mohammad Bellal Hossain, Hosseinzadeh, Mehdi, Hostiuc, Sorin, Hoveidamanesh, Soodabeh, Hsieh, Vivian Chia-rong, Hu, Guoqing, Huang, Junjie, Huda, M Mamun, Ifeagwu, Susan C, Ikuta, Kevin S, Ilesanmi, Olayinka Stephen, Irvani, Seyed Sina Naghibi, Islam, Rakibul M, Islam, Sheikh Mohammed Shariful, Ismail, Nahlah Elkudssiah, Iso, Hiroyasu, Isola, Gaetano, Itumalla, Ramaiah, Iwagami, Masao, Jahani, Mohammad Ali, Jahanmehr, Nader, Jain, Rajesh, Jakovljevic, Mihajlo, Janodia, Manthan Dilipkumar, Jayapal, Sathish Kumar, Jayaram, Shubha, Jha, Ravi Prakash, Jonas, Jost B, Joo, Tama, Joseph, Nitin, Jürisson, Mikk, Kabir, Ali, Kalankesh, Leila R, Kalhor, Rohollah, Kamath, Aruna M, Kamenov, Kaloyan, Kandel, Himal, Kantar, Rami S, Kapoor, Neeti, Karanikolos, Marina, Katikireddi, Srinivasa Vittal, Kavetskyy, Tara, Kawakami, Norito, Kayode, Gbenga A, Keikavoosi-Arani, Leila, Keykhaei, Mohammad, Khader, Yousef Saleh, Khajuria, Himanshu, Khalilov, Rovshan, Khammarnia, Mohammad, Khan, Md Nuruzzaman, Khan, Moien AB, Khan, Maseer, Khezeli, Mehdi, Kim, Min Seo, Kim, Yun Jin, Kisa, Sezer, Kisa, Adnan, Klymchuk, Vitalii, Koly, Kamrun Nahar, Korzh, Oleksii, Kosen, Soewarta, Koul, Parvaiz A, Kuate Defo, Barthelemy, Kumar, G Anil, Kusuma, Dian, Kyu, Hmwe Hmwe, Larsson, Anders O, Lasrado, Savita, Lee, Wei-Chen, Lee, Yo Han, Lee, Chiachi Bonnie, Li, Shanshan, Lucchetti, Giancarlo, Mahajan, Preetam Bhalchandra, Majeed, Azeem, Makki, Alaa, Malekzadeh, Reza, Malik, Ahmad Azam, Malta, Deborah Carvalho, Mansournia, Mohammad Ali, Mantovani, Lorenzo Giovanni, Martinez-Valle, Adolfo, Martins-Melo, Francisco Rogerlândio, Masoumi, Seyedeh Zahra, Mathur, Manu Raj, Maude, Richard Jame, Maulik, Pallab K, Mckee, Martin, Mendoza, Walter, Menezes, Ritesh G, Mensah, George A, Meretoja, Atte, Meretoja, Tuomo J, Mestrovic, Tomislav, Michalek, Irmina Maria, Mirrakhimov, Erkin M, Misganaw, Awoke, Misra, Sanjeev, Moazen, Babak, Mohammadi, Mokhtar, Mohammed, Shafiu, Moitra, Modhurima, Mokdad, Ali H, Molokhia, Mariam, Monasta, Lorenzo, Moni, Mohammad Ali, Moradi, Ghobad, Moreira, Rafael Silveira, Mosser, Jonathan F, Mostafavi, Ebrahim, Mouodi, Simin, Nagarajan, Ahamarshan Jayaraman, Nagata, Chie, Naghavi, Mohsen, Nangia, Vinay, Narasimha Swamy, Sreeniva, Narayana, Aparna Ichalangod, Nascimento, Bruno Ramo, Nassereldine, Hasan, Nayak, Biswa Prakash, Nazari, Javad, Negoi, Ionut, Nepal, Samata, Neupane Kandel, Sandhya, Ngunjiri, Josephine W, Nguyen, Huong Lan Thi, Nguyen, Cuong Tat, Ningrum, Dina Nur Anggraini, Noubiap, Jean Jacque, Oancea, Bogdan, Oghenetega, Onome Bright, Oh, In-Hwan, Olagunju, Andrew T, Olakunde, Babayemi Oluwaseun, Omar Bali, Ahmed, Omer, Emad, Onwujekwe, Obinna E, Otoiu, Adrian, Padubidri, Jagadish Rao, Palladino, Raffaele, Pana, Adrian, Panda-Jonas, Songhomitra, Pandi-Perumal, Seithikurippu R, Pardhan, Shahina, Pasupula, Deepak Kumar, Pathak, Praveen Kumar, Patton, George C, Pawar, Shrikant, Pereira, Jeevan, Pilania, Manju, Piroozi, Bakhtiar, Podder, Vivek, Pokhrel, Khem Narayan, Postma, Maarten J, Prada, Sergio I, Quazi Syed, Zahiruddin, Rabiee, Navid, Radhakrishnan, Raghu Anekal, Rahman, Md Mosfequr, Rahman, Mosiur, Rahman, Mahfuzar, Rahman, Mohammad Hifz Ur, Rahmani, Amir Masoud, Ranabhat, Chhabi Lal, Rao, Chythra R, Rao, Sowmya J, Rasella, Davide, Rawaf, Salman, Rawaf, David Laith, Rawal, Lal, Renzaho, Andre M N, Reshmi, Bhageerathy, Resnikoff, Serge, Rezapour, Aziz, Riahi, Seyed Mohammad, Ripon, Rezaul Karim, Sacco, Simona, Sadeghi, Masoumeh, Saeed, Umar, Sahebkar, Amirhossein, Sahiledengle, Biniyam, Sahoo, Harihar, Sahu, Maitreyi, Salama, Joseph S, Salamati, Payman, Samy, Abdallah M, Sanabria, Juan, Santric-Milicevic, Milena M, Sathian, Brijesh, Sawhney, Monika, Schmidt, Maria Inê, Seidu, Abdul-Aziz, Sepanlou, Sadaf G, Seylani, Allen, Shaikh, Masood Ali, Sheikh, Aziz, Shetty, Adithi, Shigematsu, Mika, Shiri, Rahman, Shivakumar, K M, Shokri, Azad, Singh, Jasvinder A, Sinha, Dhirendra Narain, Skryabin, Valentin Yurievich, Skryabina, Anna Aleksandrovna, Sofi-Mahmudi, Ahmad, Sousa, Raúl A R C, Stephens, Jacqueline H, Sun, Jing, Szócska, Mikló, Tabarés-Seisdedos, Rafael, Tadbiri, Hooman, Tamiru, Animut Tagele, Thankappan, Kavumpurathu Raman, Topor-Madry, Roman, Tovani-Palone, Marcos Roberto, Tran, Mai Thi Ngoc, Tran, Bach Xuan, Tripathi, Niharika, Tripathy, Jaya Prasad, Troeger, Christopher E, Uezono, Deinzel Roble, Ullah, Saif, Ullah, Anayat, Unnikrishnan, Bhaskaran, Vacante, Marco, Valadan Tahbaz, Sahel, Valdez, Pascual R, Vasic, Milena, Veroux, Massimiliano, Vervoort, Dominique, Violante, Francesco S, Vladimirov, Sergey Konstantinovitch, Vlassov, Vasily, Vo, Bay, Waheed, Yasir, Wamai, Richard G, Wang, Yuan-Pang, Wang, Yanzhong, Ward, Paul, Wiangkham, Taweewat, Yadav, Lalit, Yahyazadeh Jabbari, Seyed Hossein, Yamagishi, Kazumasa, Yaya, Sanni, Yazdi-Feyzabadi, Vahid, Yi, Siyan, Yiğit, Vahit, Yonemoto, Naohiro, Younis, Mustafa Z, Yu, Chuanhua, Yunusa, Ismaeel, Zaman, Sojib Bin, Zastrozhin, Mikhail Sergeevich, Zhang, Zhi-Jiang, Zhong, Chenwen, Zuniga, Yves Miel H, Lim, Stephen S, Murray, Christopher J L, Lozano, Rafael, Haakenstad, A, Yearwood, J, Fullman, N, Bintz, C, Bienhoff, K, Weaver, M, Nandakumar, V, Joffe, J, Legrand, K, Knight, M, Abbafati, C, Abbasi-Kangevari, M, Abdoli, A, Abeldano Zuniga, R, Adedeji, I, Adekanmbi, V, Adetokunboh, O, Afzal, M, Afzal, S, Agudelo-Botero, M, Ahinkorah, B, Ahmad, S, Ahmadi, A, Ahmadi, S, Ahmed, A, Ahmed Rashid, T, Aji, B, Akande-Sholabi, W, Alam, K, Al Hamad, H, Alhassan, R, Ali, L, Alipour, V, Aljunid, S, Ameyaw, E, Amin, T, Amu, H, Amugsi, D, Ancuceanu, R, Andrade, P, Anjum, A, Arabloo, J, Arab-Zozani, M, Ariffin, H, Arulappan, J, Aryan, Z, Ashraf, T, Atnafu, D, Atreya, A, Ausloos, M, Avila-Burgos, L, Ayano, G, Ayanore, M, Azari, S, Badiye, A, Baig, A, Bairwa, M, Bakkannavar, S, Baliga, S, Banik, P, Barnighausen, T, Barra, F, Barrow, A, Basu, S, Bayati, M, Belete, R, Bell, A, Bhagat, D, Bhagavathula, A, Bhardwaj, P, Bhardwaj, N, Bhaskar, S, Bhattacharyya, K, Bhutta, Z, Bibi, S, Bijani, A, Bikbov, B, Biondi, A, Bolarinwa, O, Bonny, A, Brenner, H, Buonsenso, D, Burkart, K, Busse, R, Butt, Z, Butt, N, Caetano dos Santos, F, Cahuana-Hurtado, L, Camera, L, Cardenas, R, Carneiro, V, Catala-Lopez, F, Chandan, J, Charan, J, Chavan, P, Chen, S, Choudhari, S, Chowdhury, E, Chowdhury, M, Cirillo, M, Corso, B, Dadras, O, Dahlawi, S, Dai, X, Dandona, L, Dandona, R, Dangel, W, Davila-Cervantes, C, Davletov, K, Deuba, K, Dhimal, M, Djalalinia, S, Do, H, Doshmangir, L, Duncan, B, Effiong, A, Ehsani-Chimeh, E, Elgendy, I, Elhadi, M, El Sayed, I, El Tantawi, M, Erku, D, Eskandarieh, S, Fares, J, Farzadfar, F, Ferrero, S, Ferro Desideri, L, Fischer, F, Foigt, N, Foroutan, M, Fukumoto, T, Gaal, P, Gaihre, S, Gardner, W, Garg, T, Getachew Obsa, A, Ghafourifard, M, Ghashghaee, A, Ghith, N, Gilani, S, Gill, P, Goharinezhad, S, Golechha, M, Guadamuz, J, Guo, Y, Gupta, R, Gupta, V, Hamiduzzaman, M, Hanif, A, Haro, J, Hasaballah, A, Hasan, M, Hashi, A, Hay, S, Hayat, K, Heidari, M, Heidari, G, Henry, N, Herteliu, C, Holla, R, Hossain, S, Hossain, M, Hosseinzadeh, M, Hostiuc, S, Hoveidamanesh, S, Hsieh, V, Hu, G, Huang, J, Huda, M, Ifeagwu, S, Ikuta, K, Ilesanmi, O, Irvani, S, Islam, R, Islam, S, Ismail, N, Iso, H, Isola, G, Itumalla, R, Iwagami, M, Jahani, M, Jahanmehr, N, Jain, R, Jakovljevic, M, Janodia, M, Jayapal, S, Jayaram, S, Jha, R, Jonas, J, Joo, T, Joseph, N, Jurisson, M, Kabir, A, Kalankesh, L, Kalhor, R, Kamath, A, Kamenov, K, Kandel, H, Kantar, R, Kapoor, N, Karanikolos, M, Katikireddi, S, Kavetskyy, T, Kawakami, N, Kayode, G, Keikavoosi-Arani, L, Keykhaei, M, Khader, Y, Khajuria, H, Khalilov, R, Khammarnia, M, Khan, M, Khezeli, M, Kim, M, Kim, Y, Kisa, S, Kisa, A, Klymchuk, V, Koly, K, Korzh, O, Kosen, S, Koul, P, Kuate Defo, B, Kumar, G, Kusuma, D, Kyu, H, Larsson, A, Lasrado, S, Lee, W, Lee, Y, Lee, C, Li, S, Lucchetti, G, Mahajan, P, Majeed, A, Makki, A, Malekzadeh, R, Malik, A, Malta, D, Mansournia, M, Mantovani, L, Martinez-Valle, A, Martins-Melo, F, Masoumi, S, Mathur, M, Maude, R, Maulik, P, Mckee, M, Mendoza, W, Menezes, R, Mensah, G, Meretoja, A, Meretoja, T, Mestrovic, T, Michalek, I, Mirrakhimov, E, Misganaw, A, Misra, S, Moazen, B, Mohammadi, M, Mohammed, S, Moitra, M, Mokdad, A, Molokhia, M, Monasta, L, Moni, M, Moradi, G, Moreira, R, Mosser, J, Mostafavi, E, Mouodi, S, Nagarajan, A, Nagata, C, Naghavi, M, Nangia, V, Narasimha Swamy, S, Narayana, A, Nascimento, B, Nassereldine, H, Nayak, B, Nazari, J, Negoi, I, Nepal, S, Neupane Kandel, S, Ngunjiri, J, Nguyen, H, Nguyen, C, Ningrum, D, Noubiap, J, Oancea, B, Oghenetega, O, Oh, I, Olagunju, A, Olakunde, B, Omar Bali, A, Omer, E, Onwujekwe, O, Otoiu, A, Padubidri, J, Palladino, R, Pana, A, Panda-Jonas, S, Pandi-Perumal, S, Pardhan, S, Pasupula, D, Pathak, P, Patton, G, Pawar, S, Pereira, J, Pilania, M, Piroozi, B, Podder, V, Pokhrel, K, Postma, M, Prada, S, Quazi Syed, Z, Rabiee, N, Radhakrishnan, R, Rahman, M, Rahmani, A, Ranabhat, C, Rao, C, Rao, S, Rasella, D, Rawaf, S, Rawaf, D, Rawal, L, Renzaho, A, Reshmi, B, Resnikoff, S, Rezapour, A, Riahi, S, Ripon, R, Sacco, S, Sadeghi, M, Saeed, U, Sahebkar, A, Sahiledengle, B, Sahoo, H, Sahu, M, Salama, J, Salamati, P, Samy, A, Sanabria, J, Santric-Milicevic, M, Sathian, B, Sawhney, M, Schmidt, M, Seidu, A, Sepanlou, S, Seylani, A, Shaikh, M, Sheikh, A, Shetty, A, Shigematsu, M, Shiri, R, Shivakumar, K, Shokri, A, Singh, J, Sinha, D, Skryabin, V, Skryabina, A, Sofi-Mahmudi, A, Sousa, R, Stephens, J, Sun, J, Szocska, M, Tabares-Seisdedos, R, Tadbiri, H, Tamiru, A, Thankappan, K, Topor-Madry, R, Tovani-Palone, M, Tran, M, Tran, B, Tripathi, N, Tripathy, J, Troeger, C, Uezono, D, Ullah, S, Ullah, A, Unnikrishnan, B, Vacante, M, Valadan Tahbaz, S, Valdez, P, Vasic, M, Veroux, M, Vervoort, D, Violante, F, Vladimirov, S, Vlassov, V, Vo, B, Waheed, Y, Wamai, R, Wang, Y, Ward, P, Wiangkham, T, Yadav, L, Yahyazadeh Jabbari, S, Yamagishi, K, Yaya, S, Yazdi-Feyzabadi, V, Yi, S, Yigit, V, Yonemoto, N, Younis, M, Yu, C, Yunusa, I, Zaman, S, Zastrozhin, M, Zhang, Z, Zhong, C, Zuniga, Y, Lim, S, Murray, C, Lozano, R, Bill & Melinda Gates Foundation, King Edward Medical University (Pakistán), Kuwait University (Kuwait), Romanian National Authority for Scientific Research and Innovation, Romanian Ministry of Research Innovation and Digitalization, Alexander von Humboldt Foundation, Federal Ministry of Education & Research (Alemania), Unión Europea. Comisión Europea. H2020, University of Aberdeen (Reino Unido), Novo Nordisk Foundation, National Health and Medical Research Council (Australia), National Research, Development and Innovation Office (Hungria), National Records of Scotland (Reino Unido), Medical Research Council (Reino Unido), Scottish Government (Reino Unido), Jatiya Kabi Kazi Nazrul Islam University (Bangladesh), Xiamen University Malaysia (Malasia), National Council for Scientific and Technological Development (Brasil), Ministero della Salute (Italia), Fondazione IRCCS. Istituto Nazionale dei Tumori, King College London, IRCCS Materno Infantile Burlo Garofolo (Italia), Edwards Lifesciences Foundation, Fundação de Amparo à Pesquisa do Estado de Minas Gerais (Brasil), Manipal Academy of Higher Education (India), Ministerio de Ciencia e Innovación. Centro de Excelencia Severo Ochoa (España), Government of Catalonia (España), International Center of Medical Sciences Research (Pakistán), Ain Shams University (Egipto), Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red - CIBERSAM (Salud Mental), INCLIVA Health Research Institute (España), Canadian Institutes of Health Research, Australian Government, and Ministry of Education, Science and Technological Development (Serbia)
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Adult ,Adolescent ,Population ,Global Health ,Health Services Accessibility ,Global Burden of Disease ,Health system quality ,Young Adult ,Nations ,Health systems ,health care access ,Risk Factors ,Quality-Adjusted Life Year ,Humans ,Child ,Global Burden of Disease Study 2019 ,Health-care access ,Aged ,Quality of Health Care ,quality ,performance ,The Healthcare Access and Quality Index ,Risk Factor ,Infant, Newborn ,Infant ,eu-repo/semantics/review [info] ,Public Health, Global Health, Social Medicine and Epidemiology ,General Medicine ,Health-care quality ,Middle Aged ,3141 Health care science ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,Indicator ,Medical-care ,Child, Preschool ,Deaths ,Amenable mortality ,Quality-Adjusted Life Years ,Age groups ,Trends ,Human - Abstract
Background: Health-care needs change throughout the life course. It is thus crucial to assess whether health systems provide access to quality health care for all ages. Drawing from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019), we measured the Healthcare Access and Quality (HAQ) Index overall and for select age groups in 204 locations from 1990 to 2019. Methods: We distinguished the overall HAQ Index (ages 0-74 years) from scores for select age groups: the young (ages 0-14 years), working (ages 15-64 years), and post-working (ages 65-74 years) groups. For GBD 2019, HAQ Index construction methods were updated to use the arithmetic mean of scaled mortality-to-incidence ratios (MIRs) and risk-standardised death rates (RSDRs) for 32 causes of death that should not occur in the presence of timely, quality health care. Across locations and years, MIRs and RSDRs were scaled from 0 (worst) to 100 (best) separately, putting the HAQ Index on a different relative scale for each age group. We estimated absolute convergence for each group on the basis of whether the HAQ Index grew faster in absolute terms between 1990 and 2019 in countries with lower 1990 HAQ Index scores than countries with higher 1990 HAQ Index scores and by Socio-demographic Index (SDI) quintile. SDI is a summary metric of overall development. Findings: Between 1990 and 2019, the HAQ Index increased overall (by 19·6 points, 95% uncertainty interval 17·9-21·3), as well as among the young (22·5, 19·9-24·7), working (17·2, 15·2-19·1), and post-working (15·1, 13·2-17·0) age groups. Large differences in HAQ Index scores were present across SDI levels in 2019, with the overall index ranging from 30·7 (28·6-33·0) on average in low-SDI countries to 83·4 (82·4-84·3) on average in high-SDI countries. Similarly large ranges between low-SDI and high-SDI countries, respectively, were estimated in the HAQ Index for the young (40·4-89·0), working (33·8-82·8), and post-working (30·4-79·1) groups. Absolute convergence in HAQ Index was estimated in the young group only. In contrast, divergence was estimated among the working and post-working groups, driven by slow progress in low-SDI countries. Interpretation: Although major gaps remain across levels of social and economic development, convergence in the young group is an encouraging sign of reduced disparities in health-care access and quality. However, divergence in the working and post-working groups indicates that health-care access and quality is lagging at lower levels of social and economic development. To meet the needs of ageing populations, health systems need to improve health-care access and quality for working-age adults and older populations while continuing to realise gains among the young. O Adetokunboh acknowledges support from Department of Science and Innovation and National Research Foundation. S Afzal acknowledges the institutional support of King Edward Medical University. S Aljunid acknowledges Department of Health Policy and Management, College of Public Health, Health Science Centre, Kuwait University for the approval and support to participate in this research project. M Ausloos, C Herteliu, and A Pana acknowledge partial support by a grant of the Romanian National Authority for Scientific Research and Innovation, CNDS-UEFISCDI, project number PN-III-P4-ID-PCCF-2016-0084. C Herteliu also acknowledges partial support by a grant of the Romanian Ministry of Research Innovation and Digitalization, MCID, project number ID-585-CTR-42-PFE-2021. T Bärnighausen was supported by the Alexander von Humboldt Foundation through the Alexander von Humboldt Professor award, funded by the Federal Ministry of Education and Research. B Bikbov acknowledges funding from the European Union’s Horizon 2020 research and innovation programme under Marie Sklodowska-Curie grant agreement No. 703226. Institute of Applied Health Sciences; School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Scotland. The salary for N Ghith is covered by a grant from Novo Nordisk Foundation (NNF16OC0021856). V B Gupta acknowledges funding support from National Health and Medical Research Council (NHMRC) Australia. V K Gupta acknowledges funding support from National Health and Medical Research Council (NHMRC) Australia. T Joo acknowledges support from the National Research, Development and Innovation Office of Hungary under grant RRF-2.3.1-21-2022-00006 (Data-driven Health Division of Health Security National Laboratory). S Vittal Katikireddi acknowledges funding from a NRS Senior Clinical Fellowship (SCAF/15/02), the Medical Research Council (MC_UU_00022/2), and the Scottish Government Chief Scientist Office (SPHSU17). M N Khan acknowledges the support of Jatiya Kabi Kazi Nazrul Islam University, Mymensingh, Bangladesh. Y J Kim acknowledges support from the Research Management Centre Xiamen University Malaysia [XMUMRF/2020-C6/ITCM/0004]. G Lucchetti is a grantee of the Brazilian National Council for Scientific and Technological Development Research Productivity - Level 1D. L Mantovani acknowledges support by Italian Ministry of Health Ricerca Corrente - IRCCS Multimedica. M Molokhia acknowledges support by the National Institute for Health Research Biomedical Research Center at Guy’s and St Thomas’ National Health Service Foundation Trust and King’s College London. L Monasta reports support for the present manuscript from the Italian Ministry of Health on project Ricerca Corrente 34/2017 and payments made to the Institute for Maternal and Child Health IRCCS Burlo Garofolo. R Moreira acknowledges the CNPQ productivity grant (316607/2021-5). B R Nascimento is partially supported by CNPq (Research Productivity Grant, 312382/2019-7), the Edwards Lifesciences Foundation (Improving the prevention and detection of Heart Valve disease across the Lifespan, 2021), and FAPEMIG (grant APQ-000627-20). J R Padubidri acknowledges Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, India for their constant support in conducting research. D Rasella reports financial support from the Spanish Ministry of Science and Innovation and State Research Agency through the Centro de Excelencia Severo Ochoa 2019-2023 programme (CEX2018-000806-S), and financial support from the Generalitat de Catalunya through the Centres de Recerca de Catalunya programme. U Saeed would like to acknowledge the International Center of Medical Sciences Research (ICMSR), Islamabad (44000), Pakistan. A M Samy acknowledges the support from Ain Shams University and the Egyptian Fulbright Mission Program. U Saeed would like to acknowledge Kasturba Medical College, Mangalore. Manipal Academy of Higher Education, Manipal for supporting research activities. R T-S is supported by the Spanish Ministry of Science and Innovation, Institute of Health Carlos III, CIBERSAM, INCLIVA (PID2021-129099OB-I00). D Vervoort is supported by the Canadian Institutes of Health Research (CIHR) Vanier Canada Graduate Scholarship. S B Zaman acknowledges receiving a scholarship from the Australian Government Research Training Program (RTP) in support of his academic career. Serbian part of this GBD contribution was co-financed through Grant OI 175 014 of the Ministry of Education Science and Technological Development of The Republic of Serbia. This work was supported, in whole or in part, by the Bill & Melinda Gates Foundation OPP1152504. Under the grant conditions of the Foundation, a Creative Commons Attribution 4.0 Generic License has already been assigned to the Author Accepted Manuscript version that might arise from this submission. Sí
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- 2022
5. ASSOCIATION OF DEPRESSION RISK WITH ASTHMA CONTROL, MEDICATION ADHERENCE AND QUALITY OF LIFE AMONG ADULT ASTHMATICS ATTENDING CHEST CLINIC IN A TERTIARY CARE HOSPITAL: 477
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ISMAIL, N E, AHAD, S, and MAHENDRAN, K
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- 2012
6. ASTHMA SEVERITY, EMOTIONAL AND FUNCTIONAL DISTURBANCES (QUALITY OF LIFE) AMONG OUTPATIENT ASTHMATIC ADOLESCENTS IN A TERTIARY CARE PUBLIC HOSPITAL: 095
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ISMAIL, N E, HAMEED, M A, MUHAMMAD, A S, and KHAN, MAN
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- 2012
7. IMMUNOHISTOCHEMICAL EVIDENCE FOR TH1 CYTOKINE PREDOMINANCE IN THE LIVER OF CHILDREN WITH AUTOIMMUNE HEPATITIS
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Ismail, N. E., Portmann, B., Hussain, M., Williams, R., Mieli-Vergani, G., and Vergani, D.
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- 1999
8. Density Functional Theory Studies on Guanine and Cytosine
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Zaharim, W. N., primary, Sulaiman, S., primary, Abu Bakar, S. N., primary, Ismail, N. E., primary, Rozak, H., primary, and Watanabe, I., primary
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- 2018
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9. Correlations between Lymphocytes, Mid-Cell Fractions and Granulocytes with Human Blood Characteristics Using Low Power He-Ne Laser Radiation
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Houssein, Hend A. A., primary, Jaafar, M. S., additional, Ramli, R. M., additional, Ismail, N. E., additional, Ahmad, A. L., additional, Bermakai, M. Y., additional, Yahya, A. K., additional, and Alam, Shah, additional
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- 2010
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10. Fetal Biometry of Head Circumference for Malaysian Pregnant Women
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Ramli, Remsen Maizan, primary, Jaafar, M. S., additional, Ismail, N. E., additional, Saltani, Hend A. A., additional, Ahmad, A. L., additional, Bermakai, M. Yahaya, additional, Yahya, A. K., additional, and Alam, Shah, additional
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- 2010
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11. Study on Interactions of Continuous Low Power CO[sub 2] Laser with Malaysian Molar Teeth
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Ahmad, A. L., primary, Jaafar, M. S., additional, Ramzun, M. R., additional, Bermakai, M. Yahaya, additional, Ismail, N. E., additional, Houssien, Hend A. A., additional, Yahya, A. K., additional, and Alam, Shah, additional
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- 2010
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12. Study on Interactions of Continuous Low Power CO2 Laser with Malaysian Molar Teeth.
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Ahmad, A. L., Jaafar, M. S., Ramzun, M. R., Bermakai, M. Yahaya, Ismail, N. E., and Houssien, Hend A. A.
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MOLARS ,LASERS ,DENTISTRY ,INFRARED spectra ,FOURIER transform infrared spectroscopy - Abstract
Recent studies have shown that CO
2 lasers can successfully be used at low-energy densities in dentistry. The CO2 laser is effective for a dental hard tissue since it strongly absorbs light in certain regions of the infrared spectrum because of the carbonate and hydroxyl groups in the structure. In this study, nineteen samples of molars extracted human teeth were irradiated with low power CO2 laser. Laser power of 3W, 6W, 9W, 12W, 15W and 18W, with exposure time of 5 s and 10 s, and distance between laser aperture and sample of 4 cm were used. Laser power above 18W is seen to damage the teeth. The teeth compositions were analyzed using the Fourier Transform Infrared Spectroscopy (FTIR). High laser power caused higher reflectance of the beam because the increased in temperature increasing the rate of chemical reaction, hence, the products after the irradiation. This situation can be explained by the Arrhenius equation [1]. [ABSTRACT FROM AUTHOR]- Published
- 2010
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13. Mapping magnetic anomalies of the great water tank, Kashmir smast (Pakistan)
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Saad, R., Ismail, N. E. H., Mokhtar Saidin, and Karamah, S. S.
14. Magnetic signature at rebound area of meteorite impact crater at Bukit Bunuh, Lenggong, Perak, Malaysia
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Nordiana, M. M., Saad, R., Mokhtar Saidin, Ismail, N. E. H., and Ismail, N. F. I.
15. Overburden of meteorite impact crater at Bukit Bunuh, Lenggong, Perak (Malaysia) using 2-D resistivity imaging
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Nordiana, M. M., Saad, R., Mokhtar Saidin, Ismail, N. E. H., Bery, A. A., and Rao, R. R.
16. Assessing the psychometric properties of the malaysian version of perceived diabetes self-management scale for diabetes mellitus
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Al Abboud, S. A., SOHAIL AHMAD, Ismail, N. E., and Bidin, M. B. L.
17. Bukit bunuh subsurface study using gravity method for meteorite impact indicators
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Saad, R., Mokhtar Saidin, Kiu, Y. C., and Ismail, N. E. H.
18. Subsurface study using 2-D resistivity imaging method for meteorite impact at Bukit Bunuh, Perak
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Saad, R., Mokhtar Saidin, M., Muztaza, N. M., Ismail, N. A., Ismail, N. E. H., Andy Anderson Bery, and Mohamad, E. T.
19. Structure of the Bukit Bunuh, Perak (Malaysia) impact crater using seismic refraction method
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Nordiana, M. M., Saad, R., Mokhtar Saidin, Nawawi, M. N. M., Ismail, N. A., Ismail, N. E. H., and Bery, A. A.
20. Assessing the efficacy of Enhancing Horizontal Resolution (EHR) technique using 2D resistivity method
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Nordiana, M. M., Saad, R., M Ikhsan Nawawi, Adiat, K. A. N., Ismail, N. A., Ismail, N. E. H., and Bery, A. A.
21. Integration of magnetic and 2-d resistivity methods for meteorite impact at Lenggong, Perak (Malaysia)
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Nordiana, M. M., Saad, R., Saidin, M., Ismail, N. E. H., Kiu, Y. C., Azwin, I. N., and Andy Anderson Bery
22. Mapping alluvial landscape using 2-D resistivity with EHR technique at Lembah Bujang, Kedah (Malaysia)
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Nordiana, M. M., Saad, R., Mokhtar Saidin, Shyeh, S. K., Kiu, Y. C., Ismail, N. A., and Ismail, N. E. H.
23. AN ASSESSMENT OF KNOWLEDGE OF COPD AMONG MALAYSIAN ADULTS USING MALAY VERSION OF BRISTOL COPD KNOWLEDGE QUESTIONNAIRE
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SOHAIL AHMAD, Ismail, A. I., Ghani, M. F. A., Leong, K. K., Zim, M. A. M., and Ismail, N. E.
24. A qualitative study exploring the impact of stigma in the lives of adult asthma patients in Selangor Malaysia
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SOHAIL AHMAD and Ismail, N. E.
25. Stigma in the lives of asthma patients: A review from the literature
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SOHAIL AHMAD and Ismail, N. E.
26. Diabetes mortality and trends before 25 years of age: an analysis of the Global Burden of Disease Study 2019
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Ewerton Cousin, Bruce B Duncan, Caroline Stein, Kanyin Liane Ong, Theo Vos, Cristiana Abbafati, Mohsen Abbasi-Kangevari, Michael Abdelmasseh, Amir Abdoli, Rami Abd-Rabu, Hassan Abolhassani, Eman Abu-Gharbieh, Manfred Mario Kokou Accrombessi, Qorinah Estiningtyas Sakilah Adnani, Muhammad Sohail Afzal, Gina Agarwal, Krishna K Agrawaal, Marcela Agudelo-Botero, Bright Opoku Ahinkorah, Sajjad Ahmad, Tauseef Ahmad, Keivan Ahmadi, Sepideh Ahmadi, Ali Ahmadi, Ali Ahmed, Yusra Ahmed Salih, Wuraola Akande-Sholabi, Tayyaba Akram, Hanadi Al Hamad, Ziyad Al-Aly, Jacqueline Elizabeth Alcalde-Rabanal, Vahid Alipour, Syed Mohamed Aljunid, Rajaa M Al-Raddadi, Nelson Alvis-Guzman, Saeed Amini, Robert Ancuceanu, Tudorel Andrei, Catalina Liliana Andrei, Ranjit Mohan Anjana, Adnan Ansar, Ippazio Cosimo Antonazzo, Benny Antony, Anayochukwu Edward Anyasodor, Jalal Arabloo, Damian Arizmendi, Benedetta Armocida, Anton A Artamonov, Judie Arulappan, Zahra Aryan, Samaneh Asgari, Tahira Ashraf, Thomas Astell-Burt, Prince Atorkey, Maha Moh'd Wahbi Atout, Martin Amogre Ayanore, Ashish D Badiye, Atif Amin Baig, Mohan Bairwa, Jennifer L Baker, Ovidiu Constantin Baltatu, Palash Chandra Banik, Anthony Barnett, Mark Thomaz Ugliara Barone, Francesco Barone-Adesi, Amadou Barrow, Neeraj Bedi, Rebuma Belete, Uzma Iqbal Belgaumi, Arielle Wilder Bell, Derrick A Bennett, Isabela M Bensenor, David Beran, Akshaya Srikanth Bhagavathula, Sonu Bhaskar, Krittika Bhattacharyya, Vijayalakshmi S Bhojaraja, Ali Bijani, Boris Bikbov, Setognal Birara, Virginia Bodolica, Aime Bonny, Hermann Brenner, Nikolay Ivanovich Briko, Zahid A Butt, Florentino Luciano Caetano dos Santos, Luis Alberto Cámera, Ismael R Campos-Nonato, Yin Cao, Chao Cao, Ester Cerin, Promit Ananyo Chakraborty, Joht Singh Chandan, Vijay Kumar Chattu, Simiao Chen, Jee-Young Jasmine Choi, Sonali Gajanan Choudhari, Enayet Karim Chowdhury, Dinh-Toi Chu, Barbara Corso, Omid Dadras, Xiaochen Dai, Albertino Antonio Moura Damasceno, Lalit Dandona, Rakhi Dandona, Claudio Alberto Dávila-Cervantes, Jan-Walter De Neve, Edgar Denova-Gutiérrez, Deepak Dhamnetiya, Daniel Diaz, Sanam Ebtehaj, Hisham Atan Edinur, Sahar Eftekharzadeh, Iman El Sayed, Islam Y Elgendy, Muhammed Elhadi, Mohamed A Elmonem, Mohammed Faisaluddin, Umar Farooque, Xiaoqi Feng, Eduarda Fernandes, Florian Fischer, David Flood, Marisa Freitas, Peter Andras Gaal, Mohamed M Gad, Piyada Gaewkhiew, Lemma Getacher, Mansour Ghafourifard, Reza Ghanei Gheshlagh, Ahmad Ghashghaee, Nermin Ghith, Ghozali Ghozali, Paramjit Singh Gill, Ibrahim Abdelmageed Ginawi, Ekaterina Vladimirovna Glushkova, Mahaveer Golechha, Sameer Vali Gopalani, Rafael Alves Guimarães, Rajat Das Gupta, Rajeev Gupta, Vivek Kumar Gupta, Veer Bala Gupta, Sapna Gupta, Tesfa Dejenie Habtewold, Nima Hafezi-Nejad, Rabih Halwani, Asif Hanif, Graeme J Hankey, Shafiul Haque, Ahmed I Hasaballah, Syed Shahzad Hasan, Abdiwahab Hashi, Soheil Hassanipour, Simon I Hay, Khezar Hayat, Mohammad Heidari, Mohammad Bellal Hossain Hossain, Sahadat Hossain, Mostafa Hosseini, Soodabeh Hoveidamanesh, Junjie Huang, Ayesha Humayun, Rabia Hussain, Bing-Fang Hwang, Segun Emmanuel Ibitoye, Kevin S Ikuta, Leeberk Raja Inbaraj, Usman Iqbal, Md Shariful Islam, Sheikh Mohammed Shariful Islam, Rakibul M Islam, Nahlah Elkudssiah Ismail, Gaetano Isola, Ramaiah Itumalla, Masao Iwagami, Ihoghosa Osamuyi Iyamu, Mohammad Ali Jahani, Mihajlo Jakovljevic, Ranil Jayawardena, Ravi Prakash Jha, Oommen John, Jost B Jonas, Tamas Joo, Ali Kabir, Rohollah Kalhor, Ashwin Kamath, Tanuj Kanchan, Himal Kandel, Neeti Kapoor, Gbenga A Kayode, Sewnet Adem Kebede, Pedram Keshavarz, Mohammad Keykhaei, Yousef Saleh Khader, Himanshu Khajuria, Moien AB Khan, Md Nuruzzaman Khan, Maseer Khan, Amir M Khater, Tawfik Ahmed Muthafer Khoja, Jagdish Khubchandani, Min Seo Kim, Yun Jin Kim, Ruth W Kimokoti, Sezer Kisa, Adnan Kisa, Mika Kivimäki, Vladimir Andreevich Korshunov, Oleksii Korzh, Ai Koyanagi, Kewal Krishan, Barthelemy Kuate Defo, G Anil Kumar, Nithin Kumar, Dian Kusuma, Carlo La Vecchia, Ben Lacey, Anders O Larsson, Savita Lasrado, Wei-Chen Lee, Chiachi Bonnie Lee, Paul H Lee, Shaun Wen Huey Lee, Ming-Chieh Li, Stephen S Lim, Lee-Ling Lim, Giancarlo Lucchetti, Azeem Majeed, Ahmad Azam Malik, Borhan Mansouri, Lorenzo Giovanni Mantovani, Santi Martini, Prashant Mathur, Colm McAlinden, Nafiul Mehedi, Teferi Mekonnen, Ritesh G Menezes, Amanual Getnet Mersha, Junmei Miao Jonasson, Tomasz Miazgowski, Irmina Maria Michalek, Andreea Mirica, Erkin M Mirrakhimov, Agha Zeeshan Mirza, Prasanna Mithra, Abdollah Mohammadian-Hafshejani, Reza Mohammadpourhodki, Arif Mohammed, Ali H Mokdad, Mariam Molokhia, Lorenzo Monasta, Mohammad Ali Moni, Farhad Moradpour, Rahmatollah Moradzadeh, Ebrahim Mostafavi, Ulrich Otto Mueller, Christopher J L Murray, Ahmad Mustafa, Gabriele Nagel, Vinay Nangia, Atta Abbas Naqvi, Biswa Prakash Nayak, Javad Nazari, Rawlance Ndejjo, Ruxandra Irina Negoi, Sandhya Neupane Kandel, Cuong Tat Nguyen, Huong Lan Thi Nguyen, Jean Jacques Noubiap, Christoph Nowak, Bogdan Oancea, Oluwakemi Ololade Odukoya, Ayodipupo Sikiru Oguntade, Temitope T Ojo, Andrew T Olagunju, Obinna E Onwujekwe, Alberto Ortiz, Mayowa O Owolabi, Raffaele Palladino, Songhomitra Panda-Jonas, Seithikurippu R Pandi-Perumal, Shahina Pardhan, Tarang Parekh, Mojtaba Parvizi, Veincent Christian Filipino Pepito, Arokiasamy Perianayagam, Ionela-Roxana Petcu, Manju Pilania, Vivek Podder, Roman V Polibin, Maarten J Postma, Akila Prashant, Navid Rabiee, Mohammad Rabiee, Vafa Rahimi-Movaghar, Muhammad Aziz Rahman, Md. Mosfequr Rahman, Mosiur Rahman, Setyaningrum Rahmawaty, Nazanin Rajai, Pradhum Ram, Juwel Rana, Kamal Ranabhat, Priyanga Ranasinghe, Chythra R Rao, Satish Rao, Salman Rawaf, David Laith Rawaf, Lal Rawal, Andre M N Renzaho, Nima Rezaei, Aziz Rezapour, Seyed Mohammad Riahi, Daniela Ribeiro, Jefferson Antonio Buendia Rodriguez, Leonardo Roever, Peter Rohloff, Godfrey M Rwegerera, Paul MacDaragh Ryan, Maha Mohamed Saber-Ayad, Siamak Sabour, Basema Saddik, Sahar Saeedi Moghaddam, Amirhossein Sahebkar, Harihar Sahoo, KM Saif-Ur-Rahman, Hamideh Salimzadeh, Mehrnoosh Samaei, Juan Sanabria, Milena M Santric-Milicevic, Brijesh Sathian, Thirunavukkarasu Sathish, Markus P Schlaich, Abdul-Aziz Seidu, Mario Šekerija, Nachimuthu Senthil Kumar, Allen Seylani, Masood Ali Shaikh, Hina Shamshad, Md Shajedur Rahman Shawon, Sara Sheikhbahaei, Jeevan K Shetty, Rahman Shiri, K M Shivakumar, Kerem Shuval, Jasvinder A Singh, Ambrish Singh, Valentin Yurievich Skryabin, Anna Aleksandrovna Skryabina, Ahmad Sofi-Mahmudi, Amin Soheili, Jing Sun, Viktória Szerencsés, Miklós Szócska, Rafael Tabarés-Seisdedos, Hooman Tadbiri, Eyayou Girma Tadesse, Md. Tariqujjaman, Kavumpurathu Raman Thankappan, Rekha Thapar, Nihal Thomas, Binod Timalsina, Ruoyan Tobe-Gai, Marcello Tonelli, Marcos Roberto Tovani-Palone, Bach Xuan Tran, Jaya Prasad Tripathy, Lorainne Tudor Car, Biruk Shalmeno Tusa, Riaz Uddin, Era Upadhyay, Sahel Valadan Tahbaz, Pascual R Valdez, Tommi Juhani Vasankari, Madhur Verma, Victor E Villalobos-Daniel, Sergey Konstantinovitch Vladimirov, Bay Vo, Giang Thu Vu, Rade Vukovic, Yasir Waheed, Richard G Wamai, Andrea Werdecker, Nuwan Darshana Wickramasinghe, Andrea Sylvia Winkler, Befikadu Legesse Wubishet, Xiaoyue Xu, Suowen Xu, Seyed Hossein Yahyazadeh Jabbari, Hiroshi Yatsuya, Sanni Yaya, Taklo Simeneh Yazie Yazie, Siyan Yi, Naohiro Yonemoto, Ismaeel Yunusa, Siddhesh Zadey, Sojib Bin Zaman, Maryam Zamanian, Nelson Zamora, Mikhail Sergeevich Zastrozhin, Anasthasia Zastrozhina, Zhi-Jiang Zhang, Chenwen Zhong, Mohammad Zmaili, Alimuddin Zumla, Mohsen Naghavi, Maria Inês Schmidt, Tampere University, Clinical Medicine, QE Econometrics, RS: GSBE other - not theme-related research, Department of Public Health, University of Helsinki, Cousin, E, Duncan, B, Stein, C, Ong, K, Vos, T, Abbafati, C, Abbasi-Kangevari, M, Abdelmasseh, M, Abdoli, A, Abd-Rabu, R, Abolhassani, H, Abu-Gharbieh, E, Accrombessi, M, Adnani, Q, Afzal, M, Agarwal, G, Agrawaal, K, Agudelo-Botero, M, Ahinkorah, B, Ahmad, S, Ahmad, T, Ahmadi, K, Ahmadi, S, Ahmadi, A, Ahmed, A, Ahmed Salih, Y, Akande-Sholabi, W, Akram, T, Al Hamad, H, Al-Aly, Z, Alcalde-Rabanal, J, Alipour, V, Aljunid, S, Al-Raddadi, R, Alvis-Guzman, N, Amini, S, Ancuceanu, R, Andrei, T, Andrei, C, Anjana, R, Ansar, A, Antonazzo, I, Antony, B, Anyasodor, A, Arabloo, J, Arizmendi, D, Armocida, B, Artamonov, A, Arulappan, J, Aryan, Z, Asgari, S, Ashraf, T, Astell-Burt, T, Atorkey, P, Atout, M, Ayanore, M, Badiye, A, Baig, A, Bairwa, M, Baker, J, Baltatu, O, Banik, P, Barnett, A, Barone, M, Barone-Adesi, F, Barrow, A, Bedi, N, Belete, R, Belgaumi, U, Bell, A, Bennett, D, Bensenor, I, Beran, D, Bhagavathula, A, Bhaskar, S, Bhattacharyya, K, Bhojaraja, V, Bijani, A, Bikbov, B, Birara, S, Bodolica, V, Bonny, A, Brenner, H, Briko, N, Butt, Z, Caetano dos Santos, F, Camera, L, Campos-Nonato, I, Cao, Y, Cao, C, Cerin, E, Chakraborty, P, Chandan, J, Chattu, V, Chen, S, Choi, J, Choudhari, S, Chowdhury, E, Chu, D, Corso, B, Dadras, O, Dai, X, Damasceno, A, Dandona, L, Dandona, R, Davila-Cervantes, C, De Neve, J, Denova-Gutierrez, E, Dhamnetiya, D, Diaz, D, Ebtehaj, S, Edinur, H, Eftekharzadeh, S, El Sayed, I, Elgendy, I, Elhadi, M, Elmonem, M, Faisaluddin, M, Farooque, U, Feng, X, Fernandes, E, Fischer, F, Flood, D, Freitas, M, Gaal, P, Gad, M, Gaewkhiew, P, Getacher, L, Ghafourifard, M, Ghanei Gheshlagh, R, Ghashghaee, A, Ghith, N, Ghozali, G, Gill, P, Ginawi, I, Glushkova, E, Golechha, M, Gopalani, S, Guimaraes, R, Gupta, R, Gupta, V, Gupta, S, Habtewold, T, Hafezi-Nejad, N, Halwani, R, Hanif, A, Hankey, G, Haque, S, Hasaballah, A, Hasan, S, Hashi, A, Hassanipour, S, Hay, S, Hayat, K, Heidari, M, Hossain, M, Hossain, S, Hosseini, M, Hoveidamanesh, S, Huang, J, Humayun, A, Hussain, R, Hwang, B, Ibitoye, S, Ikuta, K, Inbaraj, L, Iqbal, U, Islam, M, Islam, S, Islam, R, Ismail, N, Isola, G, Itumalla, R, Iwagami, M, Iyamu, I, Jahani, M, Jakovljevic, M, Jayawardena, R, Jha, R, John, O, Jonas, J, Joo, T, Kabir, A, Kalhor, R, Kamath, A, Kanchan, T, Kandel, H, Kapoor, N, Kayode, G, Kebede, S, Keshavarz, P, Keykhaei, M, Khader, Y, Khajuria, H, Khan, M, Khater, A, Khoja, T, Khubchandani, J, Kim, M, Kim, Y, Kimokoti, R, Kisa, S, Kisa, A, Kivimaki, M, Korshunov, V, Korzh, O, Koyanagi, A, Krishan, K, Kuate Defo, B, Kumar, G, Kumar, N, Kusuma, D, La Vecchia, C, Lacey, B, Larsson, A, Lasrado, S, Lee, W, Lee, C, Lee, P, Lee, S, Li, M, Lim, S, Lim, L, Lucchetti, G, Majeed, A, Malik, A, Mansouri, B, Mantovani, L, Martini, S, Mathur, P, Mcalinden, C, Mehedi, N, Mekonnen, T, Menezes, R, Mersha, A, Miao Jonasson, J, Miazgowski, T, Michalek, I, Mirica, A, Mirrakhimov, E, Mirza, A, Mithra, P, Mohammadian-Hafshejani, A, Mohammadpourhodki, R, Mohammed, A, Mokdad, A, Molokhia, M, Monasta, L, Moni, M, Moradpour, F, Moradzadeh, R, Mostafavi, E, Mueller, U, Murray, C, Mustafa, A, Nagel, G, Nangia, V, Naqvi, A, Nayak, B, Nazari, J, Ndejjo, R, Negoi, R, Neupane Kandel, S, Nguyen, C, Nguyen, H, Noubiap, J, Nowak, C, Oancea, B, Odukoya, O, Oguntade, A, Ojo, T, Olagunju, A, Onwujekwe, O, Ortiz, A, Owolabi, M, Palladino, R, Panda-Jonas, S, Pandi-Perumal, S, Pardhan, S, Parekh, T, Parvizi, M, Pepito, V, Perianayagam, A, Petcu, I, Pilania, M, Podder, V, Polibin, R, Postma, M, Prashant, A, Rabiee, N, Rabiee, M, Rahimi-Movaghar, V, Rahman, M, Rahmawaty, S, Rajai, N, Ram, P, Rana, J, Ranabhat, K, Ranasinghe, P, Rao, C, Rao, S, Rawaf, S, Rawaf, D, Rawal, L, Renzaho, A, Rezaei, N, Rezapour, A, Riahi, S, Ribeiro, D, Rodriguez, J, Roever, L, Rohloff, P, Rwegerera, G, Ryan, P, Saber-Ayad, M, Sabour, S, Saddik, B, Saeedi Moghaddam, S, Sahebkar, A, Sahoo, H, Saif-Ur-Rahman, K, Salimzadeh, H, Samaei, M, Sanabria, J, Santric-Milicevic, M, Sathian, B, Sathish, T, Schlaich, M, Seidu, A, Sekerija, M, Senthil Kumar, N, Seylani, A, Shaikh, M, Shamshad, H, Shawon, M, Sheikhbahaei, S, Shetty, J, Shiri, R, Shivakumar, K, Shuval, K, Singh, J, Singh, A, Skryabin, V, Skryabina, A, Sofi-Mahmudi, A, Soheili, A, Sun, J, Szerencses, V, Szocska, M, Tabares-Seisdedos, R, Tadbiri, H, Tadesse, E, Tariqujjaman, M, Thankappan, K, Thapar, R, Thomas, N, Timalsina, B, Tobe-Gai, R, Tonelli, M, Tovani-Palone, M, Tran, B, Tripathy, J, Tudor Car, L, Tusa, B, Uddin, R, Upadhyay, E, Valadan Tahbaz, S, Valdez, P, Vasankari, T, Verma, M, Villalobos-Daniel, V, Vladimirov, S, Vo, B, Vu, G, Vukovic, R, Waheed, Y, Wamai, R, Werdecker, A, Wickramasinghe, N, Winkler, A, Wubishet, B, Xu, X, Xu, S, Yahyazadeh Jabbari, S, Yatsuya, H, Yaya, S, Yazie, T, Yi, S, Yonemoto, N, Yunusa, I, Zadey, S, Zaman, S, Zamanian, M, Zamora, N, Zastrozhin, M, Zastrozhina, A, Zhang, Z, Zhong, C, Zmaili, M, Zumla, A, Naghavi, M, Schmidt, M, GBD 2019 Diabetes Mortality Collaborators, Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Value, Affordability and Sustainability (VALUE), Microbes in Health and Disease (MHD), Cousin, E., Duncan, B. B., Stein, C., Ong, K. L., Vos, T., Abbafati, C., Abbasi-Kangevari, M., Abdelmasseh, M., Abdoli, A., Abd-Rabu, R., Abolhassani, H., Abu-Gharbieh, E., Accrombessi, M. M. K., Adnani, Q. E. S., Afzal, M. S., Agarwal, G., Agrawaal, K. K., Agudelo-Botero, M., Ahinkorah, B. O., Ahmad, S., Ahmad, T., Ahmadi, K., Ahmadi, S., Ahmadi, A., Ahmed, A., Ahmed Salih, Y., Akande-Sholabi, W., Akram, T., Al Hamad, H., Al-Aly, Z., Alcalde-Rabanal, J. E., Alipour, V., Aljunid, S. M., Al-Raddadi, R. M., Alvis-Guzman, N., Amini, S., Ancuceanu, R., Andrei, T., Andrei, C. L., Anjana, R. M., Ansar, A., Antonazzo, I. C., Antony, B., Anyasodor, A. E., Arabloo, J., Arizmendi, D., Armocida, B., Artamonov, A. A., Arulappan, J., Aryan, Z., Asgari, S., Ashraf, T., Astell-Burt, T., Atorkey, P., Atout, M. M. W., Ayanore, M. A., Badiye, A. D., Baig, A. A., Bairwa, M., Baker, J. L., Baltatu, O. C., Banik, P. C., Barnett, A., Barone, M. T. U., Barone-Adesi, F., Barrow, A., Bedi, N., Belete, R., Belgaumi, U. I., Bell, A. W., Bennett, D. A., Bensenor, I. M., Beran, D., Bhagavathula, A. S., Bhaskar, S., Bhattacharyya, K., Bhojaraja, V. S., Bijani, A., Bikbov, B., Birara, S., Bodolica, V., Bonny, A., Brenner, H., Briko, N. I., Butt, Z. A., Caetano dos Santos, F. L., Camera, L. A., Campos-Nonato, I. R., Cao, Y., Cao, C., Cerin, E., Chakraborty, P. A., Chandan, J. S., Chattu, V. K., Chen, S., Choi, J. -Y. J., Choudhari, S. G., Chowdhury, E. K., Chu, D. -T., Corso, B., Dadras, O., Dai, X., Damasceno, A. A. M., Dandona, L., Dandona, R., Davila-Cervantes, C. A., De Neve, J. -W., Denova-Gutierrez, E., Dhamnetiya, D., Diaz, D., Ebtehaj, S., Edinur, H. A., Eftekharzadeh, S., El Sayed, I., Elgendy, I. Y., Elhadi, M., Elmonem, M. A., Faisaluddin, M., Farooque, U., Feng, X., Fernandes, E., Fischer, F., Flood, D., Freitas, M., Gaal, P. A., Gad, M. M., Gaewkhiew, P., Getacher, L., Ghafourifard, M., Ghanei Gheshlagh, R., Ghashghaee, A., Ghith, N., Ghozali, G., Gill, P. S., Ginawi, I. A., Glushkova, E. V., Golechha, M., Gopalani, S. V., Guimaraes, R. A., Gupta, R. D., Gupta, R., Gupta, V. K., Gupta, V. B., Gupta, S., Habtewold, T. D., Hafezi-Nejad, N., Halwani, R., Hanif, A., Hankey, G. J., Haque, S., Hasaballah, A. I., Hasan, S. S., Hashi, A., Hassanipour, S., Hay, S. I., Hayat, K., Heidari, M., Hossain, M. B. H., Hossain, S., Hosseini, M., Hoveidamanesh, S., Huang, J., Humayun, A., Hussain, R., Hwang, B. -F., Ibitoye, S. E., Ikuta, K. S., Inbaraj, L. R., Iqbal, U., Islam, M. S., Islam, S. M. S., Islam, R. M., Ismail, N. E., Isola, G., Itumalla, R., Iwagami, M., Iyamu, I. O., Jahani, M. A., Jakovljevic, M., Jayawardena, R., Jha, R. P., John, O., Jonas, J. B., Joo, T., Kabir, A., Kalhor, R., Kamath, A., Kanchan, T., Kandel, H., Kapoor, N., Kayode, G. A., Kebede, S. A., Keshavarz, P., Keykhaei, M., Khader, Y. S., Khajuria, H., Khan, M. A., Khan, M. N., Khan, M., Khater, A. M., Khoja, T. A. M., Khubchandani, J., Kim, M. S., Kim, Y. J., Kimokoti, R. W., Kisa, S., Kisa, A., Kivimaki, M., Korshunov, V. A., Korzh, O., Koyanagi, A., Krishan, K., Kuate Defo, B., Kumar, G. A., Kumar, N., Kusuma, D., La Vecchia, C., Lacey, B., Larsson, A. O., Lasrado, S., Lee, W. -C., Lee, C. B., Lee, P. H., Lee, S. W. H., Li, M. -C., Lim, S. S., Lim, L. -L., Lucchetti, G., Majeed, A., Malik, A. A., Mansouri, B., Mantovani, L. G., Martini, S., Mathur, P., Mcalinden, C., Mehedi, N., Mekonnen, T., Menezes, R. G., Mersha, A. G., Miao Jonasson, J., Miazgowski, T., Michalek, I. M., Mirica, A., Mirrakhimov, E. M., Mirza, A. Z., Mithra, P., Mohammadian-Hafshejani, A., Mohammadpourhodki, R., Mohammed, A., Mokdad, A. H., Molokhia, M., Monasta, L., Moni, M. A., Moradpour, F., Moradzadeh, R., Mostafavi, E., Mueller, U. O., Murray, C. J. L., Mustafa, A., Nagel, G., Nangia, V., Naqvi, A. A., Nayak, B. P., Nazari, J., Ndejjo, R., Negoi, R. I., Neupane Kandel, S., Nguyen, C. T., Nguyen, H. L. T., Noubiap, J. J., Nowak, C., Oancea, B., Odukoya, O. O., Oguntade, A. S., Ojo, T. T., Olagunju, A. T., Onwujekwe, O. E., Ortiz, A., Owolabi, M. O., Palladino, R., Panda-Jonas, S., Pandi-Perumal, S. R., Pardhan, S., Parekh, T., Parvizi, M., Pepito, V. C. F., Perianayagam, A., Petcu, I. -R., Pilania, M., Podder, V., Polibin, R. V., Postma, M. J., Prashant, A., Rabiee, N., Rabiee, M., Rahimi-Movaghar, V., Rahman, M. A., Rahman, M. M., Rahman, M., Rahmawaty, S., Rajai, N., Ram, P., Rana, J., Ranabhat, K., Ranasinghe, P., Rao, C. R., Rao, S., Rawaf, S., Rawaf, D. L., Rawal, L., Renzaho, A. M. N., Rezaei, N., Rezapour, A., Riahi, S. M., Ribeiro, D., Rodriguez, J. A. B., Roever, L., Rohloff, P., Rwegerera, G. M., Ryan, P. M., Saber-Ayad, M. M., Sabour, S., Saddik, B., Saeedi Moghaddam, S., Sahebkar, A., Sahoo, H., Saif-Ur-Rahman, K. M., Salimzadeh, H., Samaei, M., Sanabria, J., Santric-Milicevic, M. M., Sathian, B., Sathish, T., Schlaich, M. P., Seidu, A. -A., Sekerija, M., Senthil Kumar, N., Seylani, A., Shaikh, M. A., Shamshad, H., Shawon, M. S. R., Sheikhbahaei, S., Shetty, J. K., Shiri, R., Shivakumar, K. M., Shuval, K., Singh, J. A., Singh, A., Skryabin, V. Y., Skryabina, A. A., Sofi-Mahmudi, A., Soheili, A., Sun, J., Szerencses, V., Szocska, M., Tabares-Seisdedos, R., Tadbiri, H., Tadesse, E. G., Tariqujjaman, M., Thankappan, K. R., Thapar, R., Thomas, N., Timalsina, B., Tobe-Gai, R., Tonelli, M., Tovani-Palone, M. R., Tran, B. X., Tripathy, J. P., Tudor Car, L., Tusa, B. S., Uddin, R., Upadhyay, E., Valadan Tahbaz, S., Valdez, P. R., Vasankari, T. J., Verma, M., Villalobos-Daniel, V. E., Vladimirov, S. K., Vo, B., Vu, G. T., Vukovic, R., Waheed, Y., Wamai, R. G., Werdecker, A., Wickramasinghe, N. D., Winkler, A. S., Wubishet, B. L., Xu, X., Xu, S., Yahyazadeh Jabbari, S. H., Yatsuya, H., Yaya, S., Yazie, T. S. Y., Yi, S., Yonemoto, N., Yunusa, I., Zadey, S., Zaman, S. B., Zamanian, M., Zamora, N., Zastrozhin, M. S., Zastrozhina, A., Zhang, Z. -J., Zhong, C., Zmaili, M., Zumla, A., Naghavi, M., Schmidt, M. I., Collaborators, GBD 2019 Diabetes Mortality, and Lacey, BWH
- Subjects
Adult ,Endocrinology, Diabetes and Metabolism ,CHILDHOOD ,universal health coverage ,Global Health ,3121 Internal medicine ,Global Burden of Disease ,1117 Public Health and Health Services ,Endocrinology ,SDG 3 - Good Health and Well-being ,Risk Factors ,RA0421 ,Internal Medicine ,Humans ,Diabetes mortality ,diabetes, mortality, global burden of disease, under 25 years ,COHORT ,health care services ,COMPLICATIONS ,CHALLENGES ,Diabetes ,Mortality trends ,Age-specific diabetes ,1103 Clinical Sciences ,Public Health, Global Health, Social Medicine and Epidemiology ,BRAZIL ,Type I Diabetes ,INSULIN ,3142 Public health care science, environmental and occupational health ,the Socio-demographic Index ,Treatment ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,Diabetes Mellitus, Type 1 ,Diabetes Mellitus, Type 2 ,1101 Medical Biochemistry and Metabolomics ,diabete ,3121 General medicine, internal medicine and other clinical medicine ,ACCESS ,RA ,RC - Abstract
Background:Diabetes, particularly type 1 diabetes, at younger ages can be a largely preventable cause of death with the correct health care and services. We aimed to evaluate diabetes mortality and trends at ages younger than 25 years globally using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Methods:We used estimates of GBD 2019 to calculate international diabetes mortality at ages younger than 25 years in 1990 and 2019. Data sources for causes of death were obtained from vital registration systems, verbal autopsies, and other surveillance systems for 1990–2019. We estimated death rates for each location using the GBD Cause of Death Ensemble model. We analysed the association of age-standardised death rates per 100 000 population with the Socio-demographic Index (SDI) and a measure of universal health coverage (UHC) and described the variability within SDI quintiles. We present estimates with their 95% uncertainty intervals. Findings:In 2019, 16 300 (95% uncertainty interval 14 200 to 18 900) global deaths due to diabetes (type 1 and 2 combined) occurred in people younger than 25 years and 73·7% (68·3 to 77·4) were classified as due to type 1 diabetes. The age-standardised death rate was 0·50 (0·44 to 0·58) per 100 000 population, and 15 900 (97·5%) of these deaths occurred in low to high-middle SDI countries. The rate was 0·13 (0·12 to 0·14) per 100 000 population in the high SDI quintile, 0·60 (0·51 to 0·70) per 100 000 population in the low-middle SDI quintile, and 0·71 (0·60 to 0·86) per 100 000 population in the low SDI quintile. Within SDI quintiles, we observed large variability in rates across countries, in part explained by the extent of UHC (r2=0·62). From 1990 to 2019, age-standardised death rates decreased globally by 17·0% (−28·4 to −2·9) for all diabetes, and by 21·0% (–33·0 to −5·9) when considering only type 1 diabetes. However, the low SDI quintile had the lowest decline for both all diabetes (−13·6% [–28·4 to 3·4]) and for type 1 diabetes (−13·6% [–29·3 to 8·9]). Interpretation:Decreasing diabetes mortality at ages younger than 25 years remains an important challenge, especially in low and low-middle SDI countries. Inadequate diagnosis and treatment of diabetes is likely to be major contributor to these early deaths, highlighting the urgent need to provide better access to insulin and basic diabetes education and care. This mortality metric, derived from readily available and frequently updated GBD data, can help to monitor preventable diabetes-related deaths over time globally, aligned with the UN's Sustainable Development Targets, and serve as an indicator of the adequacy of basic diabetes care for type 1 and type 2 diabetes across nations. Funding: Bill & Melinda Gates Foundation.
- Published
- 2022
27. Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019:A Systematic Analysis for the Global Burden of Disease Study 2019
- Author
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Global Burden of Disease 2019 Cancer Collaboration, Kocarnik, JM, Compton, K, Dean, FE, Fu, W, Gaw, BL, Harvey, JD, Henrikson, HJ, Lu, D, Pennini, A, Xu, R, Ababneh, E, Abbasi-Kangevari, M, Abbastabar, H, Abd-Elsalam, SM, Abdoli, A, Abedi, A, Abidi, H, Abolhassani, H, Adedeji, IA, Adnani, QES, Advani, SM, Afzal, MS, Aghaali, M, Ahinkorah, BO, Ahmad, S, Ahmad, T, Ahmadi, A, Ahmadi, S, Ahmed Rashid, T, Ahmed Salih, Y, Akalu, GT, Aklilu, A, Akram, T, Akunna, CJ, Al Hamad, H, Alahdab, F, Al-Aly, Z, Ali, S, Alimohamadi, Y, Alipour, V, Aljunid, SM, Alkhayyat, M, Almasi-Hashiani, A, Almasri, NA, Al-Maweri, SAA, Almustanyir, S, Alonso, N, Alvis-Guzman, N, Amu, H, Anbesu, EW, Ancuceanu, R, Ansari, F, Ansari-Moghaddam, A, Antwi, MH, Anvari, D, Anyasodor, AE, Aqeel, M, Arabloo, J, Arab-Zozani, M, Aremu, O, Ariffin, H, Aripov, T, Arshad, M, Artaman, A, Arulappan, J, Asemi, Z, Asghari Jafarabadi, M, Ashraf, T, Atorkey, P, Aujayeb, A, Ausloos, M, Awedew, AF, Ayala Quintanilla, BP, Ayenew, T, Azab, MA, Azadnajafabad, S, Azari Jafari, A, Azarian, G, Azzam, AY, Badiye, AD, Bahadory, S, Baig, AA, Baker, JL, Balakrishnan, S, Banach, M, Bärnighausen, TW, Barone-Adesi, F, Barra, F, Barrow, A, Behzadifar, M, Belgaumi, UI, Bezabhe, WMM, Bezabih, YM, Bhagat, DS, Bhagavathula, AS, Bhardwaj, N, Bhardwaj, P, Bhaskar, S, Bhattacharyya, K, Bhojaraja, VS, Bibi, S, Bijani, A, Biondi, A, Bisignano, C, Bjørge, T, Bleyer, A, Blyuss, O, Bolarinwa, OA, Bolla, SR, Braithwaite, D, Brar, A, Brenner, H, Bustamante-Teixeira, MT, Butt, NS, Butt, ZA, Caetano Dos Santos, FL, Cao, Y, Carreras, G, Catalá-López, F, Cembranel, F, Cerin, E, Cernigliaro, A, Chakinala, RC, Chattu, SK, Chattu, VK, Chaturvedi, P, Chimed-Ochir, O, Cho, DY, Christopher, DJ, Chu, D-T, Chung, MT, Conde, J, Cortés, S, Cortesi, PA, Costa, VM, Cunha, AR, Dadras, O, Dagnew, AB, Dahlawi, SMA, Dai, X, Dandona, L, Dandona, R, Darwesh, AM, Das Neves, J, De la Hoz, FP, Demis, AB, Denova-Gutiérrez, E, Dhamnetiya, D, Dhimal, ML, Dhimal, M, Dianatinasab, M, Diaz, D, Djalalinia, S, Do, HP, Doaei, S, Dorostkar, F, Dos Santos Figueiredo, FW, Driscoll, TR, Ebrahimi, H, Eftekharzadeh, S, El Tantawi, M, El-Abid, H, Elbarazi, I, Elhabashy, HR, Elhadi, M, El-Jaafary, SI, Eshrati, B, Eskandarieh, S, Esmaeilzadeh, F, Etemadi, A, Ezzikouri, S, Faisaluddin, M, Faraon, EJA, Fares, J, Farzadfar, F, Feroze, AH, Ferrero, S, Ferro Desideri, L, Filip, I, Fischer, F, Fisher, JL, Foroutan, M, Fukumoto, T, Gaal, PA, Gad, MM, Gadanya, MA, Gallus, S, Gaspar Fonseca, M, Getachew Obsa, A, Ghafourifard, M, Ghashghaee, A, Ghith, N, Gholamalizadeh, M, Gilani, SA, Ginindza, TG, Gizaw, ATT, Glasbey, JC, Golechha, M, Goleij, P, Gomez, RS, Gopalani, SV, Gorini, G, Goudarzi, H, Grosso, G, Gubari, MIM, Guerra, MR, Guha, A, Gunasekera, DS, Gupta, B, Gupta, VB, Gupta, VK, Gutiérrez, RA, Hafezi-Nejad, N, Haider, MR, Haj-Mirzaian, A, Halwani, R, Hamadeh, RR, Hameed, S, Hamidi, S, Hanif, A, Haque, S, Harlianto, NI, Haro, JM, Hasaballah, AI, Hassanipour, S, Hay, RJ, Hay, SI, Hayat, K, Heidari, G, Heidari, M, Herrera-Serna, BY, Herteliu, C, Hezam, K, Holla, R, Hossain, MM, Hossain, MBH, Hosseini, M-S, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Hostiuc, S, Househ, M, Hsairi, M, Huang, J, Hugo, FN, Hussain, R, Hussein, NR, Hwang, B-F, Iavicoli, I, Ibitoye, SE, Ida, F, Ikuta, KS, Ilesanmi, OS, Ilic, IM, Ilic, MD, Irham, LM, Islam, JY, Islam, RM, Islam, SMS, Ismail, NE, Isola, G, Iwagami, M, Jacob, L, Jain, V, Jakovljevic, MB, Javaheri, T, Jayaram, S, Jazayeri, SB, Jha, RP, Jonas, JB, Joo, T, Joseph, N, Joukar, F, Jürisson, M, Kabir, A, Kahrizi, D, Kalankesh, LR, Kalhor, R, Kaliyadan, F, Kalkonde, Y, Kamath, A, Kameran Al-Salihi, N, Kandel, H, Kapoor, N, Karch, A, Kasa, AS, Katikireddi, SV, Kauppila, JH, Kavetskyy, T, Kebede, SA, Keshavarz, P, Keykhaei, M, Khader, YS, Khalilov, R, Khan, G, Khan, M, Khan, MN, Khan, MAB, Khang, Y-H, Khater, AM, Khayamzadeh, M, Kim, GR, Kim, YJ, Kisa, A, Kisa, S, Kissimova-Skarbek, K, Kopec, JA, Koteeswaran, R, Koul, PA, Koulmane Laxminarayana, SL, Koyanagi, A, Kucuk Bicer, B, Kugbey, N, Kumar, GA, Kumar, N, Kurmi, OP, Kutluk, T, La Vecchia, C, Lami, FH, Landires, I, Lauriola, P, Lee, S-W, Lee, SWH, Lee, W-C, Lee, YH, Leigh, J, Leong, E, Li, J, Li, M-C, Liu, X, Loureiro, JA, Lunevicius, R, Magdy Abd El Razek, M, Majeed, A, Makki, A, Male, S, Malik, AA, Mansournia, MA, Martini, S, Masoumi, SZ, Mathur, P, McKee, M, Mehrotra, R, Mendoza, W, Menezes, RG, Mengesha, EW, Mesregah, MK, Mestrovic, T, Miao Jonasson, J, Miazgowski, B, Miazgowski, T, Michalek, IM, Miller, TR, Mirzaei, H, Mirzaei, HR, Misra, S, Mithra, P, Moghadaszadeh, M, Mohammad, KA, Mohammad, Y, Mohammadi, M, Mohammadi, SM, Mohammadian-Hafshejani, A, Mohammed, S, Moka, N, Mokdad, AH, Molokhia, M, Monasta, L, Moni, MA, Moosavi, MA, Moradi, Y, Moraga, P, Morgado-da-Costa, J, Morrison, SD, Mosapour, A, Mubarik, S, Mwanri, L, Nagarajan, AJ, Nagaraju, SP, Nagata, C, Naimzada, MD, Nangia, V, Naqvi, AA, Narasimha Swamy, S, Ndejjo, R, Nduaguba, SO, Negoi, I, Negru, SM, Neupane Kandel, S, Nguyen, CT, Nguyen, HLT, Niazi, RK, Nnaji, CA, Noor, NM, Nuñez-Samudio, V, Nzoputam, CI, Oancea, B, Ochir, C, Odukoya, OO, Ogbo, FA, Olagunju, AT, Olakunde, BO, Omar, E, Omar Bali, A, Omonisi, AEE, Ong, S, Onwujekwe, OE, Orru, H, Ortega-Altamirano, DV, Otstavnov, N, Otstavnov, SS, Owolabi, MO, P A, M, Padubidri, JR, Pakshir, K, Pana, A, Panagiotakos, D, Panda-Jonas, S, Pardhan, S, Park, E-C, Park, E-K, Pashazadeh Kan, F, Patel, HK, Patel, JR, Pati, S, Pattanshetty, SM, Paudel, U, Pereira, DM, Pereira, RB, Perianayagam, A, Pillay, JD, Pirouzpanah, S, Pishgar, F, Podder, I, Postma, MJ, Pourjafar, H, Prashant, A, Preotescu, L, Rabiee, M, Rabiee, N, Radfar, A, Radhakrishnan, RA, Radhakrishnan, V, Rafiee, A, Rahim, F, Rahimzadeh, S, Rahman, M, Rahman, MA, Rahmani, AM, Rajai, N, Rajesh, A, Rakovac, I, Ram, P, Ramezanzadeh, K, Ranabhat, K, Ranasinghe, P, Rao, CR, Rao, SJ, Rawassizadeh, R, Razeghinia, MS, Renzaho, AMN, Rezaei, N, Rezapour, A, Roberts, TJ, Rodriguez, JAB, Rohloff, P, Romoli, M, Ronfani, L, Roshandel, G, Rwegerera, GM, S, M, Sabour, S, Saddik, B, Saeed, U, Sahebkar, A, Sahoo, H, Salehi, S, Salem, MR, Salimzadeh, H, Samaei, M, Samy, AM, Sanabria, J, Sankararaman, S, Santric-Milicevic, MM, Sardiwalla, Y, Sarveazad, A, Sathian, B, Sawhney, M, Saylan, M, Schneider, IJC, Sekerija, M, Seylani, A, Shafaat, O, Shaghaghi, Z, Shaikh, MA, Shamsoddin, E, Shannawaz, M, Sharma, R, Sheikh, A, Sheikhbahaei, S, Shetty, A, Shetty, JK, Shetty, PH, Shibuya, K, Shirkoohi, R, Shivakumar, KM, Shivarov, V, Siabani, S, Siddappa Malleshappa, SK, Silva, DAS, Singh, JA, Sintayehu, Y, Skryabin, VY, Skryabina, AA, Soeberg, MJ, Sofi-Mahmudi, A, Sotoudeh, H, Steiropoulos, P, Straif, K, Subedi, R, Sufiyan, MB, Sultan, I, Sultana, S, Sur, D, Szerencsés, V, Szócska, M, Tabarés-Seisdedos, R, Tabuchi, T, Tadbiri, H, Taherkhani, A, Takahashi, K, Talaat, IM, Tan, K-K, Tat, VY, Tedla, BAA, Tefera, YG, Tehrani-Banihashemi, A, Temsah, M-H, Tesfay, FH, Tessema, GA, Thapar, R, Thavamani, A, Thoguluva Chandrasekar, V, Thomas, N, Tohidinik, HR, Touvier, M, Tovani-Palone, MR, Traini, E, Tran, BX, Tran, KB, Tran, MTN, Tripathy, JP, Tusa, BS, Ullah, I, Ullah, S, Umapathi, KK, Unnikrishnan, B, Upadhyay, E, Vacante, M, Vaezi, M, Valadan Tahbaz, S, Velazquez, DZ, Veroux, M, Violante, FS, Vlassov, V, Vo, B, Volovici, V, Vu, GT, Waheed, Y, Wamai, RG, Ward, P, Wen, YF, Westerman, R, Winkler, AS, Yadav, L, Yahyazadeh Jabbari, SH, Yang, L, Yaya, S, Yazie, TSY, Yeshaw, Y, Yonemoto, N, Younis, MZ, Yousefi, Z, Yu, C, Yuce, D, Yunusa, I, Zadnik, V, Zare, F, Zastrozhin, MS, Zastrozhina, A, Zhang, J, Zhong, C, Zhou, L, Zhu, C, Ziapour, A, Zimmermann, IR, Fitzmaurice, C, Murray, CJL, Force, LM, Value, Affordability and Sustainability (VALUE), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Microbes in Health and Disease (MHD), Kocarnik, J, Compton, K, Dean, F, Fu, W, Gaw, B, Harvey, J, Henrikson, H, Lu, D, Pennini, A, Xu, R, Ababneh, E, Abbasi-Kangevari, M, Abbastabar, H, Abd-Elsalam, S, Abdoli, A, Abedi, A, Abidi, H, Abolhassani, H, Adedeji, I, Adnani, Q, Advani, S, Afzal, M, Aghaali, M, Ahinkorah, B, Ahmad, S, Ahmad, T, Ahmadi, A, Ahmadi, S, Ahmed Rashid, T, Ahmed Salih, Y, Akalu, G, Aklilu, A, Akram, T, Akunna, C, Al Hamad, H, Alahdab, F, Al-Aly, Z, Ali, S, Alimohamadi, Y, Alipour, V, Aljunid, S, Alkhayyat, M, Almasi-Hashiani, A, Almasri, N, Al-Maweri, S, Almustanyir, S, Alonso, N, Alvis-Guzman, N, Amu, H, Anbesu, E, Ancuceanu, R, Ansari, F, Ansari-Moghaddam, A, Antwi, M, Anvari, D, Anyasodor, A, Aqeel, M, Arabloo, J, Arab-Zozani, M, Aremu, O, Ariffin, H, Aripov, T, Arshad, M, Artaman, A, Arulappan, J, Asemi, Z, Asghari Jafarabadi, M, Ashraf, T, Atorkey, P, Aujayeb, A, Ausloos, M, Awedew, A, Ayala Quintanilla, B, Ayenew, T, Azab, M, Azadnajafabad, S, Azari Jafari, A, Azarian, G, Azzam, A, Badiye, A, Bahadory, S, Baig, A, Baker, J, Balakrishnan, S, Banach, M, Barnighausen, T, Barone-Adesi, F, Barra, F, Barrow, A, Behzadifar, M, Belgaumi, U, Bezabhe, W, Bezabih, Y, Bhagat, D, Bhagavathula, A, Bhardwaj, N, Bhardwaj, P, Bhaskar, S, Bhattacharyya, K, Bhojaraja, V, Bibi, S, Bijani, A, Biondi, A, Bisignano, C, Bjorge, T, Bleyer, A, Blyuss, O, Bolarinwa, O, Bolla, S, Braithwaite, D, Brar, A, Brenner, H, Bustamante-Teixeira, M, Butt, N, Butt, Z, Caetano Dos Santos, F, Cao, Y, Carreras, G, Catala-Lopez, F, Cembranel, F, Cerin, E, Cernigliaro, A, Chakinala, R, Chattu, S, Chattu, V, Chaturvedi, P, Chimed-Ochir, O, Cho, D, Christopher, D, Chu, D, Chung, M, Conde, J, Cortes, S, Cortesi, P, Costa, V, Cunha, A, Dadras, O, Dagnew, A, Dahlawi, S, Dai, X, Dandona, L, Dandona, R, Darwesh, A, Das Neves, J, De La Hoz, F, Demis, A, Denova-Gutierrez, E, Dhamnetiya, D, Dhimal, M, Dianatinasab, M, Diaz, D, Djalalinia, S, Do, H, Doaei, S, Dorostkar, F, Dos Santos Figueiredo, F, Driscoll, T, Ebrahimi, H, Eftekharzadeh, S, El Tantawi, M, El-Abid, H, Elbarazi, I, Elhabashy, H, Elhadi, M, El-Jaafary, S, Eshrati, B, Eskandarieh, S, Esmaeilzadeh, F, Etemadi, A, Ezzikouri, S, Faisaluddin, M, Faraon, E, Fares, J, Farzadfar, F, Feroze, A, Ferrero, S, Ferro Desideri, L, Filip, I, Fischer, F, Fisher, J, Foroutan, M, Fukumoto, T, Gaal, P, Gad, M, Gadanya, M, Gallus, S, Gaspar Fonseca, M, Getachew Obsa, A, Ghafourifard, M, Ghashghaee, A, Ghith, N, Gholamalizadeh, M, Gilani, S, Ginindza, T, Gizaw, A, Glasbey, J, Golechha, M, Goleij, P, Gomez, R, Gopalani, S, Gorini, G, Goudarzi, H, Grosso, G, Gubari, M, Guerra, M, Guha, A, Gunasekera, D, Gupta, B, Gupta, V, Gutierrez, R, Hafezi-Nejad, N, Haider, M, Haj-Mirzaian, A, Halwani, R, Hamadeh, R, Hameed, S, Hamidi, S, Hanif, A, Haque, S, Harlianto, N, Haro, J, Hasaballah, A, Hassanipour, S, Hay, R, Hay, S, Hayat, K, Heidari, G, Heidari, M, Herrera-Serna, B, Herteliu, C, Hezam, K, Holla, R, Hossain, M, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Hostiuc, S, Househ, M, Hsairi, M, Huang, J, Hugo, F, Hussain, R, Hussein, N, Hwang, B, Iavicoli, I, Ibitoye, S, Ida, F, Ikuta, K, Ilesanmi, O, Ilic, I, Ilic, M, Irham, L, Islam, J, Islam, R, Islam, S, Ismail, N, Isola, G, Iwagami, M, Jacob, L, Jain, V, Jakovljevic, M, Javaheri, T, Jayaram, S, Jazayeri, S, Jha, R, Jonas, J, Joo, T, Joseph, N, Joukar, F, Jurisson, M, Kabir, A, Kahrizi, D, Kalankesh, L, Kalhor, R, Kaliyadan, F, Kalkonde, Y, Kamath, A, Kameran Al-Salihi, N, Kandel, H, Kapoor, N, Karch, A, Kasa, A, Katikireddi, S, Kauppila, J, Kavetskyy, T, Kebede, S, Keshavarz, P, Keykhaei, M, Khader, Y, Khalilov, R, Khan, G, Khan, M, Khang, Y, Khater, A, Khayamzadeh, M, Kim, G, Kim, Y, Kisa, A, Kisa, S, Kissimova-Skarbek, K, Kopec, J, Koteeswaran, R, Koul, P, Koulmane Laxminarayana, S, Koyanagi, A, Kucuk Bicer, B, Kugbey, N, Kumar, G, Kumar, N, Kurmi, O, Kutluk, T, La Vecchia, C, Lami, F, Landires, I, Lauriola, P, Lee, S, Lee, W, Lee, Y, Leigh, J, Leong, E, Li, J, Li, M, Liu, X, Loureiro, J, Lunevicius, R, Magdy Abd El Razek, M, Majeed, A, Makki, A, Male, S, Malik, A, Mansournia, M, Martini, S, Masoumi, S, Mathur, P, Mckee, M, Mehrotra, R, Mendoza, W, Menezes, R, Mengesha, E, Mesregah, M, Mestrovic, T, Miao Jonasson, J, Miazgowski, B, Miazgowski, T, Michalek, I, Miller, T, Mirzaei, H, Misra, S, Mithra, P, Moghadaszadeh, M, Mohammad, K, Mohammad, Y, Mohammadi, M, Mohammadi, S, Mohammadian-Hafshejani, A, Mohammed, S, Moka, N, Mokdad, A, Molokhia, M, Monasta, L, Moni, M, Moosavi, M, Moradi, Y, Moraga, P, Morgado-Da-Costa, J, Morrison, S, Mosapour, A, Mubarik, S, Mwanri, L, Nagarajan, A, Nagaraju, S, Nagata, C, Naimzada, M, Nangia, V, Naqvi, A, Narasimha Swamy, S, Ndejjo, R, Nduaguba, S, Negoi, I, Negru, S, Neupane Kandel, S, Nguyen, C, Nguyen, H, Niazi, R, Nnaji, C, Noor, N, Nunez-Samudio, V, Nzoputam, C, Oancea, B, Ochir, C, Odukoya, O, Ogbo, F, Olagunju, A, Olakunde, B, Omar, E, Omar Bali, A, Omonisi, A, Ong, S, Onwujekwe, O, Orru, H, Ortega-Altamirano, D, Otstavnov, N, Otstavnov, S, Owolabi, M, P A, M, Padubidri, J, Pakshir, K, Pana, A, Panagiotakos, D, Panda-Jonas, S, Pardhan, S, Park, E, Pashazadeh Kan, F, Patel, H, Patel, J, Pati, S, Pattanshetty, S, Paudel, U, Pereira, D, Pereira, R, Perianayagam, A, Pillay, J, Pirouzpanah, S, Pishgar, F, Podder, I, Postma, M, Pourjafar, H, Prashant, A, Preotescu, L, Rabiee, M, Rabiee, N, Radfar, A, Radhakrishnan, R, Radhakrishnan, V, Rafiee, A, Rahim, F, Rahimzadeh, S, Rahman, M, Rahmani, A, Rajai, N, Rajesh, A, Rakovac, I, Ram, P, Ramezanzadeh, K, Ranabhat, K, Ranasinghe, P, Rao, C, Rao, S, Rawassizadeh, R, Razeghinia, M, Renzaho, A, Rezaei, N, Rezapour, A, Roberts, T, Rodriguez, J, Rohloff, P, Romoli, M, Ronfani, L, Roshandel, G, Rwegerera, G, Manjula, S, Sabour, S, Saddik, B, Saeed, U, Sahebkar, A, Sahoo, H, Salehi, S, Salem, M, Salimzadeh, H, Samaei, M, Samy, A, Sanabria, J, Sankararaman, S, Santric-Milicevic, M, Sardiwalla, Y, Sarveazad, A, Sathian, B, Sawhney, M, Saylan, M, Schneider, I, Sekerija, M, Seylani, A, Shafaat, O, Shaghaghi, Z, Shaikh, M, Shamsoddin, E, Shannawaz, M, Sharma, R, Sheikh, A, Sheikhbahaei, S, Shetty, A, Shetty, J, Shetty, P, Shibuya, K, Shirkoohi, R, Shivakumar, K, Shivarov, V, Siabani, S, Siddappa Malleshappa, S, Silva, D, Singh, J, Sintayehu, Y, Skryabin, V, Skryabina, A, Soeberg, M, Sofi-Mahmudi, A, Sotoudeh, H, Steiropoulos, P, Straif, K, Subedi, R, Sufiyan, M, Sultan, I, Sultana, S, Sur, D, Szerencses, V, Szocska, M, Tabares-Seisdedos, R, Tabuchi, T, Tadbiri, H, Taherkhani, A, Takahashi, K, Talaat, I, Tan, K, Tat, V, Tedla, B, Tefera, Y, Tehrani-Banihashemi, A, Temsah, M, Tesfay, F, Tessema, G, Thapar, R, Thavamani, A, Thoguluva Chandrasekar, V, Thomas, N, Tohidinik, H, Touvier, M, Tovani-Palone, M, Traini, E, Tran, B, Tran, K, Tran, M, Tripathy, J, Tusa, B, Ullah, I, Ullah, S, Umapathi, K, Unnikrishnan, B, Upadhyay, E, Vacante, M, Vaezi, M, Valadan Tahbaz, S, Velazquez, D, Veroux, M, Violante, F, Vlassov, V, Vo, B, Volovici, V, Vu, G, Waheed, Y, Wamai, R, Ward, P, Wen, Y, Westerman, R, Winkler, A, Yadav, L, Yahyazadeh Jabbari, S, Yang, L, Yaya, S, Yazie, T, Yeshaw, Y, Yonemoto, N, Younis, M, Yousefi, Z, Yu, C, Yuce, D, Yunusa, I, Zadnik, V, Zare, F, Zastrozhin, M, Zastrozhina, A, Zhang, J, Zhong, C, Zhou, L, Zhu, C, Ziapour, A, Zimmermann, I, Fitzmaurice, C, Murray, C, Force, L, Kocarnik J.M., Compton K., Dean F.E., Fu W., Gaw B.L., Harvey J.D., Henrikson H.J., Lu D., Pennini A., Xu R., Ababneh E., Abbasi-Kangevari M., Abbastabar H., Abd-Elsalam S.M., Abdoli A., Abedi A., Abidi H., Abolhassani H., Adedeji I.A., Adnani Q.E.S., Advani S.M., Afzal M.S., Aghaali M., Ahinkorah B.O., Ahmad S., Ahmad T., Ahmadi A., Ahmadi S., Ahmed Rashid T., Ahmed Salih Y., Akalu G.T., Aklilu A., Akram T., Akunna C.J., Al Hamad H., Alahdab F., Al-Aly Z., Ali S., Alimohamadi Y., Alipour V., Aljunid S.M., Alkhayyat M., Almasi-Hashiani A., Almasri N.A., Al-Maweri S.A.A., Almustanyir S., Alonso N., Alvis-Guzman N., Amu H., Anbesu E.W., Ancuceanu R., Ansari F., Ansari-Moghaddam A., Antwi M.H., Anvari D., Anyasodor A.E., Aqeel M., Arabloo J., Arab-Zozani M., Aremu O., Ariffin H., Aripov T., Arshad M., Artaman A., Arulappan J., Asemi Z., Asghari Jafarabadi M., Ashraf T., Atorkey P., Aujayeb A., Ausloos M., Awedew A.F., Ayala Quintanilla B.P., Ayenew T., Azab M.A., Azadnajafabad S., Azari Jafari A., Azarian G., Azzam A.Y., Badiye A.D., Bahadory S., Baig A.A., Baker J.L., Balakrishnan S., Banach M., Barnighausen T.W., Barone-Adesi F., Barra F., Barrow A., Behzadifar M., Belgaumi U.I., Bezabhe W.M.M., Bezabih Y.M., Bhagat D.S., Bhagavathula A.S., Bhardwaj N., Bhardwaj P., Bhaskar S., Bhattacharyya K., Bhojaraja V.S., Bibi S., Bijani A., Biondi A., Bisignano C., Bjorge T., Bleyer A., Blyuss O., Bolarinwa O.A., Bolla S.R., Braithwaite D., Brar A., Brenner H., Bustamante-Teixeira M.T., Butt N.S., Butt Z.A., Caetano dos Santos F.L., Cao Y., Carreras G., Catala-Lopez F., Cembranel F., Cerin E., Cernigliaro A., Chakinala R.C., Chattu S.K., Chattu V.K., Chaturvedi P., Chimed-Ochir O., Cho D.Y., Christopher D.J., Chu D.-T., Chung M.T., Conde J., Cortes S., Cortesi P.A., Costa V.M., Cunha A.R., Dadras O., Dagnew A.B., Dahlawi S.M.A., Dai X., Dandona L., Dandona R., Darwesh A.M., das Neves J., De la Hoz F.P., Demis A.B., Denova-Gutierrez E., Dhamnetiya D., Dhimal M.L., Dhimal M., Dianatinasab M., Diaz D., Djalalinia S., Do H.P., Doaei S., Dorostkar F., dos Santos Figueiredo F.W., Driscoll T.R., Ebrahimi H., Eftekharzadeh S., El Tantawi M., El-Abid H., Elbarazi I., Elhabashy H.R., Elhadi M., El-Jaafary S.I., Eshrati B., Eskandarieh S., Esmaeilzadeh F., Etemadi A., Ezzikouri S., Faisaluddin M., Faraon E.J.A., Fares J., Farzadfar F., Feroze A.H., Ferrero S., Ferro Desideri L., Filip I., Fischer F., Fisher J.L., Foroutan M., Fukumoto T., Gaal P.A., Gad M.M., Gadanya M.A., Gallus S., Gaspar Fonseca M., Getachew Obsa A., Ghafourifard M., Ghashghaee A., Ghith N., Gholamalizadeh M., Gilani S.A., Ginindza T.G., Gizaw A.T.T., Glasbey J.C., Golechha M., Goleij P., Gomez R.S., Gopalani S.V., Gorini G., Goudarzi H., Grosso G., Gubari M.I.M., Guerra M.R., Guha A., Gunasekera D.S., Gupta B., Gupta V.B., Gupta V.K., Gutierrez R.A., Hafezi-Nejad N., Haider M.R., Haj-Mirzaian A., Halwani R., Hamadeh R.R., Hameed S., Hamidi S., Hanif A., Haque S., Harlianto N.I., Haro J.M., Hasaballah A.I., Hassanipour S., Hay R.J., Hay S.I., Hayat K., Heidari G., Heidari M., Herrera-Serna B.Y., Herteliu C., Hezam K., Holla R., Hossain M.M., Hossain M.B.H., Hosseini M.-S., Hosseini M., Hosseinzadeh M., Hostiuc M., Hostiuc S., Househ M., Hsairi M., Huang J., Hugo F.N., Hussain R., Hussein N.R., Hwang B.-F., Iavicoli I., Ibitoye S.E., Ida F., Ikuta K.S., Ilesanmi O.S., Ilic I.M., Ilic M.D., Irham L.M., Islam J.Y., Islam R.M., Islam S.M.S., Ismail N.E., Isola G., Iwagami M., Jacob L., Jain V., Jakovljevic M.B., Javaheri T., Jayaram S., Jazayeri S.B., Jha R.P., Jonas J.B., Joo T., Joseph N., Joukar F., Jurisson M., Kabir A., Kahrizi D., Kalankesh L.R., Kalhor R., Kaliyadan F., Kalkonde Y., Kamath A., Kameran Al-Salihi N., Kandel H., Kapoor N., Karch A., Kasa A.S., Katikireddi S.V., Kauppila J.H., Kavetskyy T., Kebede S.A., Keshavarz P., Keykhaei M., Khader Y.S., Khalilov R., Khan G., Khan M., Khan M.N., Khan M.A.B., Khang Y.-H., Khater A.M., Khayamzadeh M., Kim G.R., Kim Y.J., Kisa A., Kisa S., Kissimova-Skarbek K., Kopec J.A., Koteeswaran R., Koul P.A., Koulmane Laxminarayana S.L., Koyanagi A., Kucuk Bicer B., Kugbey N., Kumar G.A., Kumar N., Kurmi O.P., Kutluk T., La Vecchia C., Lami F.H., Landires I., Lauriola P., Lee S.-W., Lee S.W.H., Lee W.-C., Lee Y.H., Leigh J., Leong E., Li J., Li M.-C., Liu X., Loureiro J.A., Lunevicius R., Magdy Abd El Razek M., Majeed A., Makki A., Male S., Malik A.A., Mansournia M.A., Martini S., Masoumi S.Z., Mathur P., McKee M., Mehrotra R., Mendoza W., Menezes R.G., Mengesha E.W., Mesregah M.K., Mestrovic T., Miao Jonasson J., Miazgowski B., Miazgowski T., Michalek I.M., Miller T.R., Mirzaei H., Mirzaei H.R., Misra S., Mithra P., Moghadaszadeh M., Mohammad K.A., Mohammad Y., Mohammadi M., Mohammadi S.M., Mohammadian-Hafshejani A., Mohammed S., Moka N., Mokdad A.H., Molokhia M., Monasta L., Moni M.A., Moosavi M.A., Moradi Y., Moraga P., Morgado-Da-Costa J., Morrison S.D., Mosapour A., Mubarik S., Mwanri L., Nagarajan A.J., Nagaraju S.P., Nagata C., Naimzada M.D., Nangia V., Naqvi A.A., Narasimha Swamy S., Ndejjo R., Nduaguba S.O., Negoi I., Negru S.M., Neupane Kandel S., Nguyen C.T., Nguyen H.L.T., Niazi R.K., Nnaji C.A., Noor N.M., Nunez-Samudio V., Nzoputam C.I., Oancea B., Ochir C., Odukoya O.O., Ogbo F.A., Olagunju A.T., Olakunde B.O., Omar E., Omar Bali A.O., Omonisi A.E.E., Ong S., Onwujekwe O.E., Orru H., Ortega-Altamirano D.V., Otstavnov N., Otstavnov S.S., Owolabi M.O., P A M., Padubidri J.R., Pakshir K., Pana A., Panagiotakos D., Panda-Jonas S., Pardhan S., Park E.-C., Park E.-K., Pashazadeh Kan F., Patel H.K., Patel J.R., Pati S., Pattanshetty S.M., Paudel U., Pereira D.M., Pereira R.B., Perianayagam A., Pillay J.D., Pirouzpanah S., Pishgar F., Podder I., Postma M.J., Pourjafar H., Prashant A., Preotescu L., Rabiee M., Rabiee N., Radfar A., Radhakrishnan R.A., Radhakrishnan V., Rafiee A., Rahim F., Rahimzadeh S., Rahman M., Rahman M.A., Rahmani A.M., Rajai N., Rajesh A., Rakovac I., Ram P., Ramezanzadeh K., Ranabhat K., Ranasinghe P., Rao C.R., Rao S.J., Rawassizadeh R., Razeghinia M.S., Renzaho A.M.N., Rezaei N., Rezapour A., Roberts T.J., Rodriguez J.A.B., Rohloff P., Romoli M., Ronfani L., Roshandel G., Rwegerera G.M., Manjula S., Sabour S., Saddik B., Saeed U., Sahebkar A., Sahoo H., Salehi S., Salem M.R., Salimzadeh H., Samaei M., Samy A.M., Sanabria J., Sankararaman S., Santric-Milicevic M.M., Sardiwalla Y., Sarveazad A., Sathian B., Sawhney M., Saylan M., Schneider I.J.J., Sekerija M., Seylani A., Shafaat O., Shaghaghi Z., Shaikh M.A., Shamsoddin E., Shannawaz M., Sharma R., Sheikh A., Sheikhbahaei S., Shetty A., Shetty J.K., Shetty P.H., Shibuya K., Shirkoohi R., Shivakumar K.M., Shivarov V., Siabani S., Siddappa Malleshappa S.K., Silva D.A.S., Singh J.A., Sintayehu Y., Skryabin V.Y., Skryabina A.A., Soeberg M.J., Sofi-Mahmudi A., Sotoudeh H., Steiropoulos P., Straif K., Subedi R., Sufiyan M.B., Sultan I., Sultana S., Sur D., Szerencses V., Szocska M., Tabares-Seisdedos R., Tabuchi T., Tadbiri H., Taherkhani A., Takahashi K., Talaat I.M., Tan K.-K., Tat V.Y., Tedla B.A.A., Tefera Y.G., Tehrani-Banihashemi A., Temsah M., Tesfay F.H., Tessema G.A., Thapar R., Thavamani A., Thoguluva Chandrasekar V., Thomas N., Tohidinik H.R., Touvier M., Tovani-Palone M.R., Traini E., Tran B.X., Tran K.B., Tran M.T.N., Tripathy J.P., Tusa B.S., Ullah I., Ullah S., Umapathi K.K., Unnikrishnan B., Upadhyay E., Vacante M., Vaezi M., Valadan Tahbaz S., Velazquez D.Z., Veroux M., Violante F.S., Vlassov V., Vo B., Volovici V., Vu G.T., Waheed Y., Wamai R.G., Ward P., Wen Y.F., Westerman R., Winkler A.S., Yadav L., Yahyazadeh Jabbari S.H., Yang L., Yaya S., Yazie T.S.Y., Yeshaw Y., Yonemoto N., Younis M.Z., Yousefi Z., Yu C., Yuce D., Yunusa I., Zadnik V., Zare F., Zastrozhin M.S., Zastrozhina A., Zhang J., Zhong C., Zhou L., Zhu C., Ziapour A., Zimmermann I.R., Fitzmaurice C., Murray C.J.L., Force L.M., Bill & Melinda Gates Foundation, American Lebanese Syrian Associated Charities, Kuwait University (Kuwait), National University of Malaysia (Malasia), Alexander von Humboldt Foundation, Federal Ministry of Education & Research (Alemania), NIH - National Cancer Institute (NCI) (Estados Unidos), Unión Europea. Comisión Europea. European Research Council (ERC), Unión Europea. Comisión Europea. H2020, Novo Nordisk Foundation, National Health and Medical Research Council (Australia), Jazan University (Arabia Saudí), Romanian National Authority for Scientific Research and Innovation, Ministry of Education (Brasil), National Heart Foundation of Australia, Ministry of Education, Science and Technological Development (Serbia), NHS - Research Scotland (Reino Unido), Medical Research Council (Reino Unido), Scottish Government (Reino Unido), Jatiya Kabi Kazi Nazrul Islam University (Bangladesh), Xiamen University (Malasia), Manipal Academy of Higher Education (India), Sistema Nacional de Investigación (Panamá), Secretaría Nacional de Ciencia, Tecnología e Innovación (Panamá), King College London, National Health Service (Reino Unido), Government of the Russian Federation, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brasil), National Council for Scientific and Technological Development (Brasil), Cancer Prevention and Research Institute of Texas (Estados Unidos), Fundação para a Ciência e Tecnologia (Portugal), Neurosurgery, Kocarnik, J. M., Compton, K., Dean, F. E., Fu, W., Gaw, B. L., Harvey, J. D., Henrikson, H. J., Lu, D., Pennini, A., Xu, R., Ababneh, E., Abbasi-Kangevari, M., Abbastabar, H., Abd-Elsalam, S. M., Abdoli, A., Abedi, A., Abidi, H., Abolhassani, H., Adedeji, I. A., Adnani, Q. E. S., Advani, S. M., Afzal, M. S., Aghaali, M., Ahinkorah, B. O., Ahmad, S., Ahmad, T., Ahmadi, A., Ahmadi, S., Ahmed Rashid, T., Ahmed Salih, Y., Akalu, G. T., Aklilu, A., Akram, T., Akunna, C. J., Al Hamad, H., Alahdab, F., Al-Aly, Z., Ali, S., Alimohamadi, Y., Alipour, V., Aljunid, S. M., Alkhayyat, M., Almasi-Hashiani, A., Almasri, N. A., Al-Maweri, S. A. A., Almustanyir, S., Alonso, N., Alvis-Guzman, N., Amu, H., Anbesu, E. W., Ancuceanu, R., Ansari, F., Ansari-Moghaddam, A., Antwi, M. H., Anvari, D., Anyasodor, A. E., Aqeel, M., Arabloo, J., Arab-Zozani, M., Aremu, O., Ariffin, H., Aripov, T., Arshad, M., Artaman, A., Arulappan, J., Asemi, Z., Asghari Jafarabadi, M., Ashraf, T., Atorkey, P., Aujayeb, A., Ausloos, M., Awedew, A. F., Ayala Quintanilla, B. P., Ayenew, T., Azab, M. A., Azadnajafabad, S., Azari Jafari, A., Azarian, G., Azzam, A. Y., Badiye, A. D., Bahadory, S., Baig, A. A., Baker, J. L., Balakrishnan, S., Banach, M., Barnighausen, T. W., Barone-Adesi, F., Barra, F., Barrow, A., Behzadifar, M., Belgaumi, U. I., Bezabhe, W. M. M., Bezabih, Y. M., Bhagat, D. S., Bhagavathula, A. S., Bhardwaj, N., Bhardwaj, P., Bhaskar, S., Bhattacharyya, K., Bhojaraja, V. S., Bibi, S., Bijani, A., Biondi, A., Bisignano, C., Bjorge, T., Bleyer, A., Blyuss, O., Bolarinwa, O. A., Bolla, S. R., Braithwaite, D., Brar, A., Brenner, H., Bustamante-Teixeira, M. T., Butt, N. S., Butt, Z. A., Caetano Dos Santos, F. L., Cao, Y., Carreras, G., Catala-Lopez, F., Cembranel, F., Cerin, E., Cernigliaro, A., Chakinala, R. C., Chattu, S. K., Chattu, V. K., Chaturvedi, P., Chimed-Ochir, O., Cho, D. Y., Christopher, D. J., Chu, D. -T., Chung, M. T., Conde, J., Cortes, S., Cortesi, P. A., Costa, V. M., Cunha, A. R., Dadras, O., Dagnew, A. B., Dahlawi, S. M. A., Dai, X., Dandona, L., Dandona, R., Darwesh, A. M., Das Neves, J., De La Hoz, F. P., Demis, A. B., Denova-Gutierrez, E., Dhamnetiya, D., Dhimal, M. L., Dhimal, M., Dianatinasab, M., Diaz, D., Djalalinia, S., Do, H. P., Doaei, S., Dorostkar, F., Dos Santos Figueiredo, F. W., Driscoll, T. R., Ebrahimi, H., Eftekharzadeh, S., El Tantawi, M., El-Abid, H., Elbarazi, I., Elhabashy, H. R., Elhadi, M., El-Jaafary, S. I., Eshrati, B., Eskandarieh, S., Esmaeilzadeh, F., Etemadi, A., Ezzikouri, S., Faisaluddin, M., Faraon, E. J. A., Fares, J., Farzadfar, F., Feroze, A. H., Ferrero, S., Ferro Desideri, L., Filip, I., Fischer, F., Fisher, J. L., Foroutan, M., Fukumoto, T., Gaal, P. A., Gad, M. M., Gadanya, M. A., Gallus, S., Gaspar Fonseca, M., Getachew Obsa, A., Ghafourifard, M., Ghashghaee, A., Ghith, N., Gholamalizadeh, M., Gilani, S. A., Ginindza, T. G., Gizaw, A. T. T., Glasbey, J. C., Golechha, M., Goleij, P., Gomez, R. S., Gopalani, S. V., Gorini, G., Goudarzi, H., Grosso, G., Gubari, M. I. M., Guerra, M. R., Guha, A., Gunasekera, D. S., Gupta, B., Gupta, V. B., Gupta, V. K., Gutierrez, R. A., Hafezi-Nejad, N., Haider, M. R., Haj-Mirzaian, A., Halwani, R., Hamadeh, R. R., Hameed, S., Hamidi, S., Hanif, A., Haque, S., Harlianto, N. I., Haro, J. M., Hasaballah, A. I., Hassanipour, S., Hay, R. J., Hay, S. I., Hayat, K., Heidari, G., Heidari, M., Herrera-Serna, B. Y., Herteliu, C., Hezam, K., Holla, R., Hossain, M. M., Hossain, M. B. H., Hosseini, M. -S., Hosseini, M., Hosseinzadeh, M., Hostiuc, M., Hostiuc, S., Househ, M., Hsairi, M., Huang, J., Hugo, F. N., Hussain, R., Hussein, N. R., Hwang, B. -F., Iavicoli, I., Ibitoye, S. E., Ida, F., Ikuta, K. S., Ilesanmi, O. S., Ilic, I. M., Ilic, M. D., Irham, L. M., Islam, J. Y., Islam, R. M., Islam, S. M. S., Ismail, N. E., Isola, G., Iwagami, M., Jacob, L., Jain, V., Jakovljevic, M. B., Javaheri, T., Jayaram, S., Jazayeri, S. B., Jha, R. P., Jonas, J. B., Joo, T., Joseph, N., Joukar, F., Jurisson, M., Kabir, A., Kahrizi, D., Kalankesh, L. R., Kalhor, R., Kaliyadan, F., Kalkonde, Y., Kamath, A., Kameran Al-Salihi, N., Kandel, H., Kapoor, N., Karch, A., Kasa, A. S., Katikireddi, S. V., Kauppila, J. H., Kavetskyy, T., Kebede, S. A., Keshavarz, P., Keykhaei, M., Khader, Y. S., Khalilov, R., Khan, G., Khan, M., Khan, M. N., Khan, M. A. B., Khang, Y. -H., Khater, A. M., Khayamzadeh, M., Kim, G. R., Kim, Y. J., Kisa, A., Kisa, S., Kissimova-Skarbek, K., Kopec, J. A., Koteeswaran, R., Koul, P. A., Koulmane Laxminarayana, S. L., Koyanagi, A., Kucuk Bicer, B., Kugbey, N., Kumar, G. A., Kumar, N., Kurmi, O. P., Kutluk, T., La Vecchia, C., Lami, F. H., Landires, I., Lauriola, P., Lee, S. -W., Lee, S. W. H., Lee, W. -C., Lee, Y. H., Leigh, J., Leong, E., Li, J., Li, M. -C., Liu, X., Loureiro, J. A., Lunevicius, R., Magdy Abd El Razek, M., Majeed, A., Makki, A., Male, S., Malik, A. A., Mansournia, M. A., Martini, S., Masoumi, S. Z., Mathur, P., Mckee, M., Mehrotra, R., Mendoza, W., Menezes, R. G., Mengesha, E. W., Mesregah, M. K., Mestrovic, T., Miao Jonasson, J., Miazgowski, B., Miazgowski, T., Michalek, I. M., Miller, T. R., Mirzaei, H., Mirzaei, H. R., Misra, S., Mithra, P., Moghadaszadeh, M., Mohammad, K. A., Mohammad, Y., Mohammadi, M., Mohammadi, S. M., Mohammadian-Hafshejani, A., Mohammed, S., Moka, N., Mokdad, A. H., Molokhia, M., Monasta, L., Moni, M. A., Moosavi, M. A., Moradi, Y., Moraga, P., Morgado-Da-Costa, J., Morrison, S. D., Mosapour, A., Mubarik, S., Mwanri, L., Nagarajan, A. J., Nagaraju, S. P., Nagata, C., Naimzada, M. D., Nangia, V., Naqvi, A. A., Narasimha Swamy, S., Ndejjo, R., Nduaguba, S. O., Negoi, I., Negru, S. M., Neupane Kandel, S., Nguyen, C. T., Nguyen, H. L. T., Niazi, R. K., Nnaji, C. A., Noor, N. M., Nunez-Samudio, V., Nzoputam, C. I., Oancea, B., Ochir, C., Odukoya, O. O., Ogbo, F. A., Olagunju, A. T., Olakunde, B. O., Omar, E., Omar Bali, A., Omonisi, A. E. E., Ong, S., Onwujekwe, O. E., Orru, H., Ortega-Altamirano, D. V., Otstavnov, N., Otstavnov, S. S., Owolabi, M. O., P A, M., Padubidri, J. R., Pakshir, K., Pana, A., Panagiotakos, D., Panda-Jonas, S., Pardhan, S., Park, E. -C., Park, E. -K., Pashazadeh Kan, F., Patel, H. K., Patel, J. R., Pati, S., Pattanshetty, S. M., Paudel, U., Pereira, D. M., Pereira, R. B., Perianayagam, A., Pillay, J. D., Pirouzpanah, S., Pishgar, F., Podder, I., Postma, M. J., Pourjafar, H., Prashant, A., Preotescu, L., Rabiee, M., Rabiee, N., Radfar, A., Radhakrishnan, R. A., Radhakrishnan, V., Rafiee, A., Rahim, F., Rahimzadeh, S., Rahman, M., Rahman, M. A., Rahmani, A. 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J., Sofi-Mahmudi, A., Sotoudeh, H., Steiropoulos, P., Straif, K., Subedi, R., Sufiyan, M. B., Sultan, I., Sultana, S., Sur, D., Szerencses, V., Szocska, M., Tabares-Seisdedos, R., Tabuchi, T., Tadbiri, H., Taherkhani, A., Takahashi, K., Talaat, I. M., Tan, K. -K., Tat, V. Y., Tedla, B. A. A., Tefera, Y. G., Tehrani-Banihashemi, A., Temsah, M. -H., Tesfay, F. H., Tessema, G. A., Thapar, R., Thavamani, A., Thoguluva Chandrasekar, V., Thomas, N., Tohidinik, H. R., Touvier, M., Tovani-Palone, M. R., Traini, E., Tran, B. X., Tran, K. B., Tran, M. T. N., Tripathy, J. P., Tusa, B. S., Ullah, I., Ullah, S., Umapathi, K. K., Unnikrishnan, B., Upadhyay, E., Vacante, M., Vaezi, M., Valadan Tahbaz, S., Velazquez, D. Z., Veroux, M., Violante, F. S., Vlassov, V., Vo, B., Volovici, V., Vu, G. T., Waheed, Y., Wamai, R. G., Ward, P., Wen, Y. F., Westerman, R., Winkler, A. S., Yadav, L., Yahyazadeh Jabbari, S. H., Yang, L., Yaya, S., Yazie, T. S. Y., Yeshaw, Y., Yonemoto, N., Younis, M. Z., Yousefi, Z., Yu, C., Yuce, D., Yunusa, I., Zadnik, V., Zare, F., Zastrozhin, M. S., Zastrozhina, A., Zhang, J., Zhong, C., Zhou, L., Zhu, C., Ziapour, A., Zimmermann, I. R., Fitzmaurice, C., Murray, C. J. L., and Force, L. M.
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Cancer Research ,GBD ,195 COUNTRIES ,Global Health ,1117 Public Health and Health Services ,Global Burden of Disease ,SDG 3 - Good Health and Well-being ,WORLDWIDE ,Risk Factors ,Neoplasms ,SURVEILLANCE ,SUPPORT ,Global Burden of Disease 2019 Cancer Collaboration ,Prevalence ,Online First ,cancer ,Humans ,1112 Oncology and Carcinogenesis ,public health, cancer, burden of diseases ,PROGRESS ,Original Investigation ,Global burden ,Science & Technology ,CHALLENGES ,Research ,Incidence ,Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762 [VDP] ,COVID-19 ,1112 Oncology and Carcinogenesis, 1117 Public Health and Health Services ,Disability-Adjusted Life Years ,mortality ,STATISTICS ,Oncology ,Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019 A Systematic Analysis for the Global Burden of Disease Study 2019 ,HEALTH-CARE ,TERRITORIES ,Quality-Adjusted Life Years ,Life Sciences & Biomedicine ,Comments - Abstract
Key Points Question What was the burden of cancer globally and across Sociodemographic Index (SDI) groupings in 2019, and how has incidence, morbidity, and mortality changed since 2010? Findings In this systematic analysis, there were 23.6 million new global cancer cases in 2019 (17.2 million when excluding those with nonmelanoma skin cancer), 10.0 million cancer deaths, and an estimated 250 million disability-adjusted life years estimated to be due to cancer; since 2010, these represent increases of 26.3%, 20.9%, and 16.0%, respectively. Absolute cancer burden increased in all SDI quintiles since 2010, but the largest percentage increases occurred in the low and low-middle SDI quintiles. Meanings The study results suggest that increased cancer prevention and control efforts are needed to equitably address the evolving and increasing burden of cancer across the SDI spectrum., Importance The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden. Objective To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic Index (SDI) quintiles from 2010 to 2019. Evidence Review The GBD 2019 estimation methods were used to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life years (DALYs) in 2019 and over the past decade. Estimates are also provided by quintiles of the SDI, a composite measure of educational attainment, income per capita, and total fertility rate for those younger than 25 years. Estimates include 95% uncertainty intervals (UIs). Findings In 2019, there were an estimated 23.6 million (95% UI, 22.2-24.9 million) new cancer cases (17.2 million when excluding nonmelanoma skin cancer) and 10.0 million (95% UI, 9.36-10.6 million) cancer deaths globally, with an estimated 250 million (235-264 million) DALYs due to cancer. Since 2010, these represented a 26.3% (95% UI, 20.3%-32.3%) increase in new cases, a 20.9% (95% UI, 14.2%-27.6%) increase in deaths, and a 16.0% (95% UI, 9.3%-22.8%) increase in DALYs. Among 22 groups of diseases and injuries in the GBD 2019 study, cancer was second only to cardiovascular diseases for the number of deaths, years of life lost, and DALYs globally in 2019. Cancer burden differed across SDI quintiles. The proportion of years lived with disability that contributed to DALYs increased with SDI, ranging from 1.4% (1.1%-1.8%) in the low SDI quintile to 5.7% (4.2%-7.1%) in the high SDI quintile. While the high SDI quintile had the highest number of new cases in 2019, the middle SDI quintile had the highest number of cancer deaths and DALYs. From 2010 to 2019, the largest percentage increase in the numbers of cases and deaths occurred in the low and low-middle SDI quintiles. Conclusions and Relevance The results of this systematic analysis suggest that the global burden of cancer is substantial and growing, with burden differing by SDI. These results provide comprehensive and comparable estimates that can potentially inform efforts toward equitable cancer control around the world., The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 examines cancer burden and trends globally for 204 countries and territories and by Socio-demographic Index quintiles from 2010 to 2019.
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- 2022
28. Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
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Brittney S Sheena, Lindsey Hiebert, Hannah Han, Helen Ippolito, Mohsen Abbasi-Kangevari, Zeinab Abbasi-Kangevari, Hedayat Abbastabar, Amir Abdoli, Hiwa Abubaker Ali, Mesafint Molla Adane, Oyelola A Adegboye, Qorinah Estiningtyas Sakilah Adnani, Shailesh M Advani, Muhammad Sohail Afzal, Saira Afzal, Mohamad Aghaie Meybodi, Bahman Ahadinezhad, Bright Opoku Ahinkorah, Sajjad Ahmad, Tauseef Ahmad, Sepideh Ahmadi, Haroon Ahmed, Muktar Beshir Ahmed, Tarik Ahmed Rashid, Gizachew Taddesse Akalu, Addis Aklilu, Tayyaba Akram, Hanadi Al Hamad, Fares Alahdab, Adugnaw Zeleke Alem, Dejene Tsegaye Alem, Fadwa Alhalaiqa Naji Alhalaiqa, Robert Kaba Alhassan, Liaqat Ali, Muhammad Ashar Ali, Yousef Alimohamadi, Vahid Alipour, Motasem Alkhayyat, Sami Almustanyir, Rajaa M Al-Raddadi, Haya Altawalah, Saeed Amini, Hubert Amu, Robert Ancuceanu, Catalina Liliana Andrei, Tudorel Andrei, Amir Anoushiravani, Adnan Ansar, Anayochukwu Edward Anyasodor, Jalal Arabloo, Morteza Arab-Zozani, Ayele Mamo Argaw, Zeleke Gebru Argaw, Muhammad Arshad, Anton A Artamonov, Tahira Ashraf, Daniel Atlaw, Floriane Ausloos, Marcel Ausloos, Sina Azadnajafabad, Mohammadreza Azangou-Khyavy, Amirhossein Azari Jafari, Ghasem Azarian, Sayna Bagheri, Saeed Bahadory, Atif Amin Baig, Maciej Banach, Nastaran Barati, Amadou Barrow, Abdul-Monim Mohammad Batiha, Diana Fernanda Bejarano Ramirez, Uzma Iqbal Belgaumi, Alemshet Yirga Berhie, Devidas S Bhagat, Nikha Bhardwaj, Pankaj Bhardwaj, Krittika Bhattacharyya, Vijayalakshmi S Bhojaraja, Ali Bijani, Antonio Biondi, Belay Boda Abule Bodicha, Hunduma Amensisa Bojia, Archith Boloor, Cristina Bosetti, Dejana Braithwaite, Nikolay Ivanovich Briko, Zahid A Butt, Luis Alberto Cámera, Raja Chandra Chakinala, Promit Ananyo Chakraborty, Jaykaran Charan, Shu Chen, Jee-Young Jasmine Choi, Sonali Gajanan Choudhari, Fazle Rabbi Chowdhury, Dinh-Toi Chu, Sheng-Chia Chung, Paolo Angelo Cortesi, Benjamin C Cowie, Garland T Culbreth, Omid Dadras, Xiaochen Dai, Lalit Dandona, Rakhi Dandona, Fernando Pio De la Hoz, Sisay Abebe Debela, Mohammed Gebre Dedefo, Feleke Mekonnen Demeke, Takele Gezahegn G Demie, Getu Debalkie Demissie, Meseret Derbew Molla, Abebaw Alemayehu Desta, Deepak Dhamnetiya, Mandira Lamichhane Dhimal, Meghnath Dhimal, Mojtaba Didehdar, Linh Phuong Doan, Fariba Dorostkar, Thomas M Drake, Fatemeh Eghbalian, Michael Ekholuenetale, Iman El Sayed, Maysaa El Sayed Zaki, Muhammed Elhadi, Mohamed A Elmonem, Aisha Elsharkawy, Shymaa Enany, Daniel Berhanie Enyew, Ryenchindorj Erkhembayar, Sharareh Eskandarieh, Firooz Esmaeilzadeh, Sayeh Ezzikouri, Hossein Farrokhpour, Getahun Fetensa, Florian Fischer, Masoud Foroutan, Mohamed M Gad, Abhay Motiramji Gaidhane, Shilpa Gaidhane, Natalie C Galles, Silvano Gallus, Teferi Gebru Gebremeskel, Eyob Alemayehu Gebreyohannes, Keyghobad Ghadiri, Kazem Ghaffari, Mansour Ghafourifard, Seyyed-Hadi Ghamari, Ahmad Ghashghaee, Ali Gholami, Abdolmajid Gholizadeh, Aima Gilani, Amit Goel, Mahaveer Golechha, Pouya Goleij, Davide Golinelli, Giuseppe Gorini, Yitayal Ayalew Goshu, Max G Griswold, Mohammed Ibrahim Mohialdeen Gubari, Bhawna Gupta, Sapna Gupta, Veer Bala Gupta, Vivek Kumar Gupta, Rasool Haddadi, Rabih Halwani, Saeed S Hamid, Samer Hamidi, Asif Hanif, Shafiul Haque, Harapan Harapan, Arief Hargono, Sanam Hariri, Ahmed I Hasaballah, S M Mahmudul Hasan, Soheil Hassanipour, Hadi Hassankhani, Simon I Hay, Khezar Hayat, Golnaz Heidari, Claudiu Herteliu, Demisu Zenbaba Heyi, Kamal Hezam, Ramesh Holla, Mohammad-Salar Hosseini, Mostafa Hosseini, Mehdi Hosseinzadeh, Mihaela Hostiuc, Mowafa Househ, Junjie Huang, Nawfal R Hussein, Ivo Iavicoli, Segun Emmanuel Ibitoye, Olayinka Stephen Ilesanmi, Irena M Ilic, Milena D Ilic, Lalu Muhammad Irham, Jessica Y Islam, Nahlah Elkudssiah Ismail, Kathryn H Jacobsen, Farhad Jadidi-Niaragh, Amirreza Javadi Mamaghani, Shubha Jayaram, Ranil Jayawardena, Rime Jebai, Ravi Prakash Jha, Nitin Joseph, Farahnaz Joukar, Billingsley Kaambwa, Ali Kabir, Zubair Kabir, Rohollah Kalhor, 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Liver Cirrhosis ,Hepatology ,Seroepidemiologic Studies ,3121 General medicine, internal medicine and other clinical medicine ,Liver Neoplasms ,Gastroenterology ,Humans ,Bayes Theorem ,HBV, Global burden of diseases, HCC, Cirrhosis ,Child ,Hepatitis B ,Global Burden of Disease - Abstract
Publisher Copyright: © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Background: Combating viral hepatitis is part of the UN Sustainable Development Goals (SDGs), and WHO has put forth hepatitis B elimination targets in its Global Health Sector Strategy on Viral Hepatitis (WHO-GHSS) and Interim Guidance for Country Validation of Viral Hepatitis Elimination (WHO Interim Guidance). We estimated the global, regional, and national prevalence of hepatitis B virus (HBV), as well as mortality and disability-adjusted life-years (DALYs) due to HBV, as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. This included estimates for 194 WHO member states, for which we compared our estimates to WHO elimination targets. Methods: The primary data sources were population-based serosurveys, claims and hospital discharges, cancer registries, vital registration systems, and published case series. We estimated chronic HBV infection and the burden of HBV-related diseases, defined as an aggregate of cirrhosis due to hepatitis B, liver cancer due to hepatitis B, and acute hepatitis B. We used DisMod-MR 2.1, a Bayesian mixed-effects meta-regression tool, to estimate the prevalence of chronic HBV infection, cirrhosis, and aetiological proportions of cirrhosis. We used mortality-to-incidence ratios modelled with spatiotemporal Gaussian process regression to estimate the incidence of liver cancer. We used the Cause of Death Ensemble modelling (CODEm) model, a tool that selects models and covariates on the basis of out-of-sample performance, to estimate mortality due to cirrhosis, liver cancer, and acute hepatitis B. Findings: In 2019, the estimated global, all-age prevalence of chronic HBV infection was 4·1% (95% uncertainty interval [UI] 3·7 to 4·5), corresponding to 316 million (284 to 351) infected people. There was a 31·3% (29·0 to 33·9) decline in all-age prevalence between 1990 and 2019, with a more marked decline of 76·8% (76·2 to 77·5) in prevalence in children younger than 5 years. HBV-related diseases resulted in 555 000 global deaths (487 000 to 630 000) in 2019. The number of HBV-related deaths increased between 1990 and 2019 (by 5·9% [–5·6 to 19·2]) and between 2015 and 2019 (by 2·9% [–5·9 to 11·3]). By contrast, all-age and age-standardised death rates due to HBV-related diseases decreased during these periods. We compared estimates for 2019 in 194 WHO locations to WHO-GHSS 2020 targets, and found that four countries achieved a 10% reduction in deaths, 15 countries achieved a 30% reduction in new cases, and 147 countries achieved a 1% prevalence in children younger than 5 years. As of 2019, 68 of 194 countries had already achieved the 2030 target proposed in WHO Interim Guidance of an all-age HBV-related death rate of four per 100 000. Interpretation: The prevalence of chronic HBV infection declined over time, particularly in children younger than 5 years, since the introduction of hepatitis B vaccination. HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and cohort effects. By 2019, many countries had met the interim seroprevalence target for children younger than 5 years, but few countries had met the WHO-GHSS interim targets for deaths and new cases. Progress according to all indicators must be accelerated to meet 2030 targets, and there are marked disparities in burden and progress across the world. HBV interventions, such as vaccination, testing, and treatment, must be strategically supported and scaled up to achieve elimination. Funding: Bill & Melinda Gates Foundation.
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- 2022
29. Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019
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Hmwe Hmwe Kyu, Avina Vongpradith, Sarah Brooke Sirota, Amanda Novotney, Christopher E Troeger, Matthew C Doxey, Rose G Bender, Jorge R Ledesma, Molly H Biehl, Samuel B Albertson, Joseph Jon Frostad, Katrin Burkart, Fiona B Bennitt, Jeff T Zhao, William M Gardner, Hailey Hagins, Dana Bryazka, Regina-Mae Villanueva Dominguez, Semagn Mekonnen Abate, Michael Abdelmasseh, Amir Abdoli, Gholamreza Abdoli, Aidin Abedi, Vida Abedi, Tadesse M Abegaz, Hassan Abidi, Richard Gyan Aboagye, Hassan Abolhassani, Yonas Derso Abtew, Hiwa Abubaker Ali, Eman Abu-Gharbieh, Ahmed Abu-Zaid, Kidist Adamu, Isaac Yeboah Addo, Oyelola A Adegboye, Mohammad Adnan, Qorinah Estiningtyas Sakilah Adnani, Muhammad Sohail Afzal, Saira Afzal, Bright Opoku Ahinkorah, Aqeel Ahmad, Araz Ramazan Ahmad, Sajjad Ahmad, Ali Ahmadi, Sepideh Ahmadi, Haroon Ahmed, Jivan Qasim Ahmed, Tarik Ahmed Rashid, Mostafa Akbarzadeh-Khiavi, Hanadi Al Hamad, Luciana Albano, Mamoon A Aldeyab, Bezatu Mengistie Alemu, Kefyalew Addis Alene, 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Adult ,Male ,Global Health ,Time ,Global Burden of Disease ,SDG 3 - Good Health and Well-being ,Risk Factors ,RA0421 ,RA0421 Public health. Hygiene. Preventive Medicine ,Humans ,Ambient air-quality ,Child ,Respiratory Tract Infections ,Aged ,Aged, 80 and over ,MCC ,Sex Characteristics ,Malnutrition ,Pyridinolcarbamate ,Bayes Theorem ,3rd-DAS ,3142 Public health care science, environmental and occupational health ,Infectious Diseases ,3121 General medicine, internal medicine and other clinical medicine ,Child, Preschool ,Female ,Particulate Matter ,Quality-Adjusted Life Years ,Covid-19 ,LRI - Abstract
Funding: Bill & Melinda Gates Foundation. Background: The global burden of lower respiratory infections (LRIs) and corresponding risk factors in children older than 5 years and adults has not been studied as comprehensively as it has been in children younger than 5 years. We assessed the burden and trends of LRIs and risk factors across all age groups by sex, for 204 countries and territories. Methods: In this analysis of data for the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we used clinician-diagnosed pneumonia or bronchiolitis as our case definition for LRIs. We included International Classification of Diseases 9th edition codes 079.6, 466–469, 470.0, 480–482.8, 483.0–483.9, 484.1–484.2, 484.6–484.7, and 487–489 and International Classification of Diseases 10th edition codes A48.1, A70, B97.4–B97.6, J09–J15.8, J16–J16.9, J20–J21.9, J91.0, P23.0–P23.4, and U04–U04.9. We used the Cause of Death Ensemble modelling strategy to analyse 23 109 site-years of vital registration data, 825 site-years of sample vital registration data, 1766 site-years of verbal autopsy data, and 681 site-years of mortality surveillance data. We used DisMod-MR 2.1, a Bayesian meta-regression tool, to analyse age–sex-specific incidence and prevalence data identified via systematic reviews of the literature, population-based survey data, and claims and inpatient data. Additionally, we estimated age–sex-specific LRI mortality that is attributable to the independent effects of 14 risk factors. Findings: Globally, in 2019, we estimated that there were 257 million (95% uncertainty interval [UI] 240–275) LRI incident episodes in males and 232 million (217–248) in females. In the same year, LRIs accounted for 1·30 million (95% UI 1·18–1·42) male deaths and 1·20 million (1·07–1·33) female deaths. Age-standardised incidence and mortality rates were 1·17 times (95% UI 1·16–1·18) and 1·31 times (95% UI 1·23–1·41) greater in males than in females in 2019. Between 1990 and 2019, LRI incidence and mortality rates declined at different rates across age groups and an increase in LRI episodes and deaths was estimated among all adult age groups, with males aged 70 years and older having the highest increase in LRI episodes (126·0% [95% UI 121·4–131·1]) and deaths (100·0% [83·4–115·9]). During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). The leading risk factors for LRI mortality varied across age groups and sex. More than half of global LRI deaths in children younger than 5 years were attributable to child wasting (population attributable fraction [PAF] 53·0% [95% UI 37·7–61·8] in males and 56·4% [40·7–65·1] in females), and more than a quarter of LRI deaths among those aged 5–14 years were attributable to household air pollution (PAF 26·0% [95% UI 16·6–35·5] for males and PAF 25·8% [16·3–35·4] for females). PAFs of male LRI deaths attributed to smoking were 20·4% (95% UI 15·4–25·2) in those aged 15–49 years, 30·5% (24·1–36·9) in those aged 50–69 years, and 21·9% (16·8–27·3) in those aged 70 years and older. PAFs of female LRI deaths attributed to household air pollution were 21·1% (95% UI 14·5–27·9) in those aged 15–49 years and 18·2% (12·5–24·5) in those aged 50–69 years. For females aged 70 years and older, the leading risk factor, ambient particulate matter, was responsible for 11·7% (95% UI 8·2–15·8) of LRI deaths. Interpretation: The patterns and progress in reducing the burden of LRIs and key risk factors for mortality varied across age groups and sexes. The progress seen in children younger than 5 years was clearly a result of targeted interventions, such as vaccination and reduction of exposure to risk factors. Similar interventions for other age groups could contribute to the achievement of multiple Sustainable Development Goals targets, including promoting wellbeing at all ages and reducing health inequalities. Interventions, including addressing risk factors such as child wasting, smoking, ambient particulate matter pollution, and household air pollution, would prevent deaths and reduce health disparities. Publisher PDF
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- 2022
30. Global, regional, and national burden of stroke and its risk factors, 1990–2019 : a systematic analysis for the Global Burden of Disease Study 2019
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Mosiur Rahman, Rehab Salah, Mario F P Peres, Licia Iacoviello, Benjamin A Stark, Mahalaqua Nazli Khatib, Amir Radfar, Kamarul Imran Musa, Yannick Béjot, Deanna Anderlini, Carlos Cantú-Brito, Feng Sha, V. E. Nwatah, Pradip Gyanwali, Boris Bikbov, Bartosz Miazgowski, Sindhura Lakshmi Koulmane Laxminarayana, Ali Bijani, Imteyaz A Khan, Yaser Mokhayeri, Bogdan Oancea, Tarang Parekh, Martin Dichgans, Linh Gia Vu, Naohiro Yonemoto, Ahmad Ghashghaee, Marcos Roberto Tovani-Palone, Gebiyaw Wudie Tsegaye, Mona Pathak, Maciej Banach, Marissa B Reitsma, Derrick A Bennett, Treska S Hassan, Allen Seylani, Gdiom Gebreheat Abady, Islam Y. Elgendy, Hassan Mehmood Lak, Ismael R. Campos-Nonato, Sorin Hostiuc, Sheikh Mohammed Shariful Islam, Alessandra C. Goulart, Silvia Schiavolin, Simona Sacco, Atif Amin Baig, Azeem Majeed, Sahar Eftekharzadeh, Badr Hasan Sobaih, Archith Boloor, Aimé Bonny, Graeme J. Hankey, Jiregna Darega Gela, Mohamed I Hegazy, Pedram Keshavarz, Segun Emmanuel Ibitoye, Maseer Khan, Hatem Abdelaziz Mohamed Wafa, Hualiang Lin, Enayet Karim Chowdhury, Simon I. Hay, Vanessa De la Cruz-Góngora, Xuefeng Liu, Arokiasamy Perianayagam, Maryam Zamanian, Sezer Kisa, Preetam Bhalchandra Mahajan, Junmei Miao Jonasson, Alberto Raggi, Shubha Jayaram, Tahira Ashraf, Ejaz Ahmad Khan, Matthias Endres, Masoumeh Sadeghi, Dominique Vervoort, Hanadi Al Hamad, Mowafa Househ, Elena V. Gnedovskaya, Johan Ärnlöv, Andrea Sylvia Winkler, Yousef Khader, Mikhail Sergeevich Zastrozhin, Yuming Guo, Yunquan Zhang, Sami Almustanyir, Lalit Dandona, Amir Masoud Rahmani, Chythra R Rao, Giancarlo Lucchetti, Irena Ilic, Suzanne Barker-Collo, Priya Rathi, Emerito Jose A. Faraon, Mohamad-Hani Temsah, Reza Ghanei Gheshlagh, Gyu Ri Kim, Carlos A Castañeda-Orjuela, Alaa Makki, Yun Jin Kim, Vida Abedi, Shanshan Li, Kewal Krishan, David Flood, Abdollah Mohammadian-Hafshejani, Michele Romoli, Gregory A. Roth, Jagdish Khubchandani, Isabela M. Benseñor, Rupak Desai, Mohammed Shannawaz, Aziz Sheikh, Claudiu Herteliu, Xiaoyue Xu, Santi Martini, Kenji Shibuya, Jasvinder A. Singh, Ravi Prakash Jha, Kairat Davletov, Mahya Beheshti, Rahmatollah Moradzadeh, Ismaeel Yunusa, Maria Inês Schmidt, Koustuv Dalal, Sohail Ahmad, Patrick D. M. C. Katoto, Oladimeji Adebayo, Nima Hafezi-Nejad, Ranil Jayawardena, Giampiero Mazzaglia, Mitra Abbasifard, Usman Iqbal, Hamid Yimam Hassen, Alireza Rafiei, Catherine O. Johnson, Mark Thomaz Ugliara Barone, Simona Giampaoli, Gaetano Isola, Ricardo Lutzky Saute, Mandira Lamichhane Dhimal, Vishnu Renjith, Farshad Farzadfar, Irina Filip, Daniel Diaz, André Karch, Samer Hamidi, Diego Augusto Santos Silva, David Colozza, Gbenga A. Kayode, Dinh-Toi Chu, Truong-Minh Pham, Arielle Wilder Bell, Aziz Rezapour, David Laith Rawaf, Anasthasia Zastrozhina, Yves Miel H Zuniga, Ivo Iavicoli, Adrian Pana, Salman Rawaf, Pankaj Bhardwaj, Omid Dadras, Anayat Ullah, Gina Agarwal, Shafiu Mohammed, Bing-Fang Hwang, Eyayou Girma Tadesse, Charles D.A. Wolfe, Sanjay Basu, Michael Brauer, Tanuj Kanchan, Ahmad Azam Malik, Brigid Unim, Min Seo Kim, Kia Vosoughi, Tomasz Miazgowski, Warren D. Lo, Vivek Podder, Dana Bryazka, Chuanhua Yu, Hassan Magdy Abd El Razek, Rufus Akinyemi, Zhi-Jiang Zhang, Ettore Beghi, Xiaochen Dai, Meghnath Dhimal, Mehrnoosh Samaei, Sathish Kumar Jayapal, Bay Vo, Amanual Getnet Mersha, Rajaa Al-Raddadi, Savita Lasrado, Jalal Arabloo, Pablo M. Lavados, Samaneh Akbarpour, Khezar Hayat, Ritesh G. Menezes, Vahid Alipour, Sowmya J. Rao, Mariam Molokhia, Trang Huyen Nguyen, Aletta E. Schutte, Zahra Kamiab, Lidia Morawska, Mohammad Ali Moni, Bo Norrving, Tommi Vasankari, Bruno Ramos Nascimento, Ai Koyanagi, Tissa Wijeratne, Rizwan Kalani, Chenwen Zhong, Bright Opoku Ahinkorah, Sepideh Ahmadi, Bruce Bartholow Duncan, Andrzej Rynkiewicz, Pradyumna Agasthi, Saeed Shahabi, Adnan Kisa, Fares Alahdab, Vafa Rahimi-Movaghar, Adnan Ansar, Matilde Leonardi, Ali Koolivand, Jefferson Antonio Buendia Rodriguez, Leonardo Roever, Daniel Asfaw Erku, Alok Atreya, Jean Jacques Noubiap, Dhaval Kolte, Shajedur Rahman Shawon, Michael Ekholuenetale, Navid Manafi, Narayanaswamy Venketasubramanian, Syed Amir Gilani, Mohamed M. Gad, Christopher J L Murray, Louis Jacob, Robert Ancuceanu, Simona Costanzo, Erkin M. Mirrakhimov, Seyed Hossein Yahyazadeh Jabbari, Nazanin Rajai, Muhammed Elhadi, Abdelrahman Ibrahim Abushouk, Alireza Zandifar, Walter Muruet, Jagadish Rao Padubidri, Promit Ananyo Chakraborty, Hans Orru, Mikk Jürisson, Rajeev Gupta, Kurnia Dwi Artanti, Till Bärnighausen, Mark Woodward, Masao Iwagami, Brijesh Sathian, Bingyu Li, Vijay Krishnamoorthy, Ahamarshan Jayaraman Nagarajan, Sherief Ghozy, Amanda G. Thrift, Michael A. Piradov, Florian Fischer, Mayowa O. Owolabi, Lorenzo G. Mantovani, Aman Yesuf Endries, Sara Sheikhbahaei, Stefan Lorkowski, Muhammed Shahriar Zaman, Ali Yadollahpour, Abdiwahab Hashi, Sreenivas Narasimha Swamy, Krittika Bhattacharyya, Hiroshi Yatsuya, Mika Kivimäki, Olayinka Stephen Ilesanmi, Irmina Maria Michalek, Ruxandra Irina Negoi, Alberico L. Catapano, Gholamreza Bazmandegan, Ahmed Al Montasir, Fakher Rahim, Amirhossein Sahebkar, Syed Mohamed Aljunid, Giang Thu Vu, G Anil Kumar, Juan Jesus Carrero, Hiroyasu Iso, Abdallah M. Samy, Stefan Stortecky, Reza Malekzadeh, Ashwin Kamath, Nevine El Nahas, Ayesha Humayun, Miguel A Barboza, Sheng-Chia Chung, Carlo La Vecchia, Oluwakemi Ololade Odukoya, Rita Krishnamurthi, Masood Ali Shaikh, Milena Ilic, Lalit Yadav, Nahlah Elkudssiah Ismail, Abdel Douiri, Yousef Mohammad, Jason H Y Wu, Sahar Saeedi Moghaddam, Ramesh Holla, Sadaf G. Sepanlou, Itamar S. Santos, Jost B. Jonas, Dian Kusuma, Atte Meretoja, Yasir Waheed, Ben Lacey, Zahra Aryan, Mulugeta Molla Birhanu, Moien Ab Khan, K. M. Saif-Ur-Rahman, Ramin Zand, Anna Aleksandrovna Skryabina, Sung In Jang, Rakhi Dandona, Emanuele D'Amico, Priyanga Ranasinghe, Jaykaran Charan, Bhaskaran Unnikrishnan, Davide Sattin, Akram Pourshams, Markus P. Schlaich, Arief Hargono, Samaneh Asgari, Ovidiu Baltatu, Ippazio Cosimo Antonazzo, Sandhya Neupane Kandel, Nizal Sarrafzadegan, Jakub Morze, Man Mohan Mehndiratta, Manjari Tripathi, Panniyammakal Jeemon, Rohollah Kalhor, Yogeshwar Kalkonde, Soraya Siabani, Sojib Bin Zaman, Seyed Sina Naghibi Irvani, Shilpa Gaidhane, Sahel Valadan Tahbaz, Yihienew Mequanint Bezabih, Samath D Dharmaratne, Ingan Ukur Tarigan, Vivek Gupta, Klara Dokova, Alireza Vakilian, Vardhmaan Jain, Akshaya Srikanth Bhagavathula, Sarah Wulf Hanson, Umar Farooque, Mohammad Ali Mansournia, Vera Marisa Costa, Alessandro Gialluisi, Valery L. Feigin, Himal Kandel, Suzanne Polinder, Nermin Ghith, Deepak Dhamnetiya, Michael H. Criqui, Asif Hanif, Ahmed Abualhasan, Veer Bala Gupta, Mahaveer Golechha, Bach Xuan Tran, Jason A. Anderson, Catherine Bisignano, Kazumasa Yamagishi, Zahid A Butt, Budi Aji, Baye Dagnew, Rasmus Havmoeller, Victor Volovici, Jitendra Singh, Paramjit Gill, Saverio Stranges, Eun Cheol Park, Andrew T Olagunju, Milena Santric-Milicevic, Woldesellassie M. Bezabhe, Sheikh M. Alif, Junjie Huang, Foad Abd-Allah, Yvonne Teuschl, Rajkumar Doshi, Nelson Alvis-Guzman, Marcel Ausloos, Mohsen Naghavi, Yusra Ahmed Salih, Mohsen Abbasi-Kangevari, Maarten J. Postma, Ghozali Ghozali, Yanzhong Wang, Ali H. Mokdad, Valentin Yurievich Skryabin, Nitin Joseph, Andre M. N. Renzaho, Muhammad Aziz Rahman, Mohammad Athar, Rustam Al-Shahi Salman, Albertino Damasceno, Fatemeh Pashazadeh Kan, Marcello Tonelli, Florentino Luciano Caetano dos Santos, Sonali G. Choudhari, Abdullah Hamid Feroze, Walter D. Johnson, Ro-Ting Lin, Francesca Giulia Magnani, Hermann Brenner, Shaimaa I. El-Jaafary, Tea Lallukka, Niveen M E Abu-Rmeileh, Jacek Jerzy Jozwiak, GBD 2019 Stroke Collaborators, Feigin, V. L., Stark, B. A., Johnson, C. O., Roth, G. A., Bisignano, C., Abady, G. G., Abbasifard, M., Abbasi-Kangevari, M., Abd-Allah, F., Abedi, V., Abualhasan, A., Abu-Rmeileh, N. M. E., Abushouk, A. I., Adebayo, O. M., Agarwal, G., Agasthi, P., Ahinkorah, B. O., Ahmad, S., Ahmadi, S., Salih, Y. A., Aji, B., Akbarpour, S., Akinyemi, R. O., Al Hamad, H., Alahdab, F., Alif, S. M., Alipour, V., Aljunid, S. M., Almustanyir, S., Al-Raddadi, R. M., Salman, R. A. -S., Alvis-Guzman, N., Ancuceanu, R., Anderlini, D., Anderson, J. A., Ansar, A., Antonazzo, I. C., Arabloo, J., Arnlov, J., Artanti, K. D., Aryan, Z., Asgari, S., Ashraf, T., Athar, M., Atreya, A., Ausloos, M., Baig, A. A., Baltatu, O. C., Banach, M., Barboza, M. A., Barker-Collo, S. L., Barnighausen, T. W., Barone, M. T. U., Basu, S., Bazmandegan, G., Beghi, E., Beheshti, M., Bejot, Y., Bell, A. W., Bennett, D. A., Bensenor, I. M., Bezabhe, W. M., Bezabih, Y. M., Bhagavathula, A. S., Bhardwaj, P., Bhattacharyya, K., Bijani, A., Bikbov, B., Birhanu, M. M., Boloor, A., Bonny, A., Brauer, M., Brenner, H., Bryazka, D., Butt, Z. A., Dos Santos, F. L. C., Campos-Nonato, I. R., Cantu-Brito, C., Carrero, J. J., Castaneda-Orjuela, C. A., Catapano, A. L., Chakraborty, P. A., Charan, J., Choudhari, S. G., Chowdhury, E. K., Chu, D. -T., Chung, S. -C., Colozza, D., Costa, V. M., Costanzo, S., Criqui, M. H., Dadras, O., Dagnew, B., Dai, X., Dalal, K., Damasceno, A. A. M., D'Amico, E., Dandona, L., Dandona, R., Gela, J. D., Davletov, K., De La Cruz-Gongora, V., Desai, R., Dhamnetiya, D., Dharmaratne, S. D., Dhimal, M. L., Dhimal, M., Diaz, D., Dichgans, M., Dokova, K., Doshi, R., Douiri, A., Duncan, B. B., Eftekharzadeh, S., Ekholuenetale, M., El Nahas, N., Elgendy, I. Y., Elhadi, M., El-Jaafary, S. I., Endres, M., Endries, A. Y., Erku, D. A., Faraon, E. J. A., Farooque, U., Farzadfar, F., Feroze, A. H., Filip, I., Fischer, F., Flood, D., Gad, M. M., Gaidhane, S., Gheshlagh, R. G., Ghashghaee, A., Ghith, N., Ghozali, G., Ghozy, S., Gialluisi, A., Giampaoli, S., Gilani, S. A., Gill, P. S., Gnedovskaya, E. V., Golechha, M., Goulart, A. C., Guo, Y., Gupta, R., Gupta, V. B., Gupta, V. K., Gyanwali, P., Hafezi-Nejad, N., Hamidi, S., Hanif, A., Hankey, G. J., Hargono, A., Hashi, A., Hassan, T. S., Hassen, H. Y., Havmoeller, R. J., Hay, S. I., Hayat, K., Hegazy, M. I., Herteliu, C., Holla, R., Hostiuc, S., Househ, M., Huang, J., Humayun, A., Hwang, B. -F., Iacoviello, L., Iavicoli, I., Ibitoye, S. E., Ilesanmi, O. S., Ilic, I. M., Ilic, M. D., Iqbal, U., Irvani, S. S. N., Islam, S. M. S., Ismail, N. E., Iso, H., Isola, G., Iwagami, M., Jacob, L., Jain, V., Jang, S. -I., Jayapal, S. K., Jayaram, S., Jayawardena, R., Jeemon, P., Jha, R. P., Johnson, W. D., Jonas, J. B., Joseph, N., Jozwiak, J. J., Jurisson, M., Kalani, R., Kalhor, R., Kalkonde, Y., Kamath, A., Kamiab, Z., Kanchan, T., Kandel, H., Karch, A., Katoto, P. D. M. C., Kayode, G. A., Keshavarz, P., Khader, Y. S., Khan, E. A., Khan, I. A., Khan, M., Khan, M. A. B., Khatib, M. N., Khubchandani, J., Kim, G. R., Kim, M. S., Kim, Y. J., Kisa, A., Kisa, S., Kivimaki, M., Kolte, D., Koolivand, A., Laxminarayana, S. L. K., Koyanagi, A., Krishan, K., Krishnamoorthy, V., Krishnamurthi, R. V., Kumar, G. A., Kusuma, D., Vecchia, C. L., Lacey, B., Lak, H. M., Lallukka, T., Lasrado, S., Lavados, P. M., Leonardi, M., Li, B., Li, S., Lin, H., Lin, R. -T., Liu, X., Lo, W. D., Lorkowski, S., Lucchetti, G., Saute, R. L., Abd El Razek, H. M., Magnani, F. G., Mahajan, P. B., Majeed, A., Makki, A., Malekzadeh, R., Malik, A. A., Manafi, N., Mansournia, M. A., Mantovani, L. G., Martini, S., Mazzaglia, G., Mehndiratta, M. M., Menezes, R. G., Meretoja, A., Mersha, A. G., Jonasson, J. M., Miazgowski, B., Miazgowski, T., Michalek, I. M., Mirrakhimov, E. M., Mohammad, Y., Mohammadian-Hafshejani, A., Mohammed, S., Mokdad, A. H., Mokhayeri, Y., Molokhia, M., Moni, M. A., Al Montasir, A., Moradzadeh, R., Morawska, L., Morze, J., Muruet, W., Musa, K. I., Nagarajan, A. J., Naghavi, M., Swamy, S. N., Nascimento, B. R., Negoi, R. I., Kandel, S. N., Nguyen, T. H., Norrving, B., Noubiap, J. J., Nwatah, V. E., Oancea, B., Odukoya, O. O., Olagunju, A. T., Orru, H., Owolabi, M. O., Padubidri, J. R., Pana, A., Parekh, T., Park, E. -C., Kan, F. P., Pathak, M., Peres, M. F. P., Perianayagam, A., Pham, T. -M., Piradov, M. A., Podder, V., Polinder, S., Postma, M. J., Pourshams, A., Radfar, A., Rafiei, A., Raggi, A., Rahim, F., Rahimi-Movaghar, V., Rahman, M., Rahman, M. A., Rahmani, A. M., Rajai, N., Ranasinghe, P., Rao, C. R., Rao, S. J., Rathi, P., Rawaf, D. L., Rawaf, S., Reitsma, M. B., Renjith, V., Renzaho, A. M. N., Rezapour, A., Rodriguez, J. A. B., Roever, L., Romoli, M., Rynkiewicz, A., Sacco, S., Sadeghi, M., Moghaddam, S. S., Sahebkar, A., Saif-Ur-Rahman, K. M., Salah, R., Samaei, M., Samy, A. M., Santos, I. S., Santric-Milicevic, M. M., Sarrafzadegan, N., Sathian, B., Sattin, D., Schiavolin, S., Schlaich, M. P., Schmidt, M. I., Schutte, A. E., Sepanlou, S. G., Seylani, A., Sha, F., Shahabi, S., Shaikh, M. A., Shannawaz, M., Shawon, Md. S. R., Sheikh, A., Sheikhbahaei, S., Shibuya, K., Siabani, S., Silva, D. A. S., Singh, J. A., Singh, J. K., Skryabin, V. Y., Skryabina, A. A., Sobaih, B. H., Stortecky, S., Stranges, S., Tadesse, E. G., Tarigan, I. U., Temsah, M. -H., Teuschl, Y., Thrift, A. G., Tonelli, M., Tovani-Palone, M. R., Tran, B. X., Tripathi, M., Tsegaye, G. W., Ullah, A., Unim, B., Unnikrishnan, B., Vakilian, A., Tahbaz, S. V., Vasankari, T. J., Venketasubramanian, N., Vervoort, D., Vo, B., Volovici, V., Vosoughi, K., Vu, G. T., Vu, L. G., Wafa, H. A., Waheed, Y., Wang, Y., Wijeratne, T., Winkler, A. S., Wolfe, C. D. A., Woodward, M., Wu, J. H., Hanson, S. W., Xu, X., Yadav, L., Yadollahpour, A., Jabbari, S. H. Y., Yamagishi, K., Yatsuya, H., Yonemoto, N., Yu, C., Yunusa, I., Zaman, M. S., Zaman, S. B., Zamanian, M., Zand, R., Zandifar, A., Zastrozhin, M. S., Zastrozhina, A., Zhang, Y., Zhang, Z. -J., Zhong, C., Zuniga, Y. M. H., Murray, C. J. L., Public Health, Neurosurgery, Department of Public Health, University of Helsinki, Faculty of Medicine, Helsinki Inequality Initiative (INEQ), HUS Neurocenter, Neurologian yksikkö, Helsinki University Hospital Area, Feigin, V, Stark, B, Johnson, C, Roth, G, Bisignano, C, Abady, G, Abbasifard, M, Abbasi-Kangevari, M, Abd-Allah, F, Abedi, V, Abualhasan, A, Abu-Rmeileh, N, Abushouk, A, Adebayo, O, Agarwal, G, Agasthi, P, Ahinkorah, B, Ahmad, S, Ahmadi, S, Salih, Y, Aji, B, Akbarpour, S, Akinyemi, R, Al Hamad, H, Alahdab, F, Alif, S, Alipour, V, Aljunid, S, Almustanyir, S, Al-Raddadi, R, Salman, R, Alvis-Guzman, N, Ancuceanu, R, Anderlini, D, Anderson, J, Ansar, A, Antonazzo, I, Arabloo, J, Arnlov, J, Artanti, K, Aryan, Z, Asgari, S, Ashraf, T, Athar, M, Atreya, A, Ausloos, M, Baig, A, Baltatu, O, Banach, M, Barboza, M, Barker-Collo, S, Barnighausen, T, Barone, M, Basu, S, Bazmandegan, G, Beghi, E, Beheshti, M, Bejot, Y, Bell, A, Bennett, D, Bensenor, I, Bezabhe, W, Bezabih, Y, Bhagavathula, A, Bhardwaj, P, Bhattacharyya, K, Bijani, A, Bikbov, B, Birhanu, M, Boloor, A, Bonny, A, Brauer, M, Brenner, H, Bryazka, D, Butt, Z, Dos Santos, F, Campos-Nonato, I, Cantu-Brito, C, Carrero, J, Castaneda-Orjuela, C, Catapano, A, Chakraborty, P, Charan, J, Choudhari, S, Chowdhury, E, Chu, D, Chung, S, Colozza, D, Costa, V, Costanzo, S, Criqui, M, Dadras, O, Dagnew, B, Dai, X, Dalal, K, Damasceno, A, D'Amico, E, Dandona, L, Dandona, R, Gela, J, Davletov, K, De La Cruz-Gongora, V, Desai, R, Dhamnetiya, D, Dharmaratne, S, Dhimal, M, Diaz, D, Dichgans, M, Dokova, K, Doshi, R, Douiri, A, Duncan, B, Eftekharzadeh, S, Ekholuenetale, M, El Nahas, N, Elgendy, I, Elhadi, M, El-Jaafary, S, Endres, M, Endries, A, Erku, D, Faraon, E, Farooque, U, Farzadfar, F, Feroze, A, Filip, I, Fischer, F, Flood, D, Gad, M, Gaidhane, S, Gheshlagh, R, Ghashghaee, A, Ghith, N, Ghozali, G, Ghozy, S, Gialluisi, A, Giampaoli, S, Gilani, S, Gill, P, Gnedovskaya, E, Golechha, M, Goulart, A, Guo, Y, Gupta, R, Gupta, V, Gyanwali, P, Hafezi-Nejad, N, Hamidi, S, Hanif, A, Hankey, G, Hargono, A, Hashi, A, Hassan, T, Hassen, H, Havmoeller, R, Hay, S, Hayat, K, Hegazy, M, Herteliu, C, Holla, R, Hostiuc, S, Househ, M, Huang, J, Humayun, A, Hwang, B, Iacoviello, L, Iavicoli, I, Ibitoye, S, Ilesanmi, O, Ilic, I, Ilic, M, Iqbal, U, Irvani, S, Islam, S, Ismail, N, Iso, H, Isola, G, Iwagami, M, Jacob, L, Jain, V, Jang, S, Jayapal, S, Jayaram, S, Jayawardena, R, Jeemon, P, Jha, R, Johnson, W, Jonas, J, Joseph, N, Jozwiak, J, Jurisson, M, Kalani, R, Kalhor, R, Kalkonde, Y, Kamath, A, Kamiab, Z, Kanchan, T, Kandel, H, Karch, A, Katoto, P, Kayode, G, Keshavarz, P, Khader, Y, Khan, E, Khan, I, Khan, M, Khatib, M, Khubchandani, J, Kim, G, Kim, M, Kim, Y, Kisa, A, Kisa, S, Kivimaki, M, Kolte, D, Koolivand, A, Laxminarayana, S, Koyanagi, A, Krishan, K, Krishnamoorthy, V, Krishnamurthi, R, Kumar, G, Kusuma, D, Vecchia, C, Lacey, B, Lak, H, Lallukka, T, Lasrado, S, Lavados, P, Leonardi, M, Li, B, Li, S, Lin, H, Lin, R, Liu, X, Lo, W, Lorkowski, S, Lucchetti, G, Saute, R, Abd El Razek, H, Magnani, F, Mahajan, P, Majeed, A, Makki, A, Malekzadeh, R, Malik, A, Manafi, N, Mansournia, M, Mantovani, L, Martini, S, Mazzaglia, G, Mehndiratta, M, Menezes, R, Meretoja, A, Mersha, A, Jonasson, J, Miazgowski, B, Miazgowski, T, Michalek, I, Mirrakhimov, E, Mohammad, Y, Mohammadian-Hafshejani, A, Mohammed, S, Mokdad, A, Mokhayeri, Y, Molokhia, M, Moni, M, Al Montasir, A, Moradzadeh, R, Morawska, L, Morze, J, Muruet, W, Musa, K, Nagarajan, A, Naghavi, M, Swamy, S, Nascimento, B, Negoi, R, Kandel, S, Nguyen, T, Norrving, B, Noubiap, J, Nwatah, V, Oancea, B, Odukoya, O, Olagunju, A, Orru, H, Owolabi, M, Padubidri, J, Pana, A, Parekh, T, Park, E, Kan, F, Pathak, M, Peres, M, Perianayagam, A, Pham, T, Piradov, M, Podder, V, Polinder, S, Postma, M, Pourshams, A, Radfar, A, Rafiei, A, Raggi, A, Rahim, F, Rahimi-Movaghar, V, Rahman, M, Rahmani, A, Rajai, N, Ranasinghe, P, Rao, C, Rao, S, Rathi, P, Rawaf, D, Rawaf, S, Reitsma, M, Renjith, V, Renzaho, A, Rezapour, A, Rodriguez, J, Roever, L, Romoli, M, Rynkiewicz, A, Sacco, S, Sadeghi, M, Moghaddam, S, Sahebkar, A, Saif-Ur-Rahman, K, Salah, R, Samaei, M, Samy, A, Santos, I, Santric-Milicevic, M, Sarrafzadegan, N, Sathian, B, Sattin, D, Schiavolin, S, Schlaich, M, Schmidt, M, Schutte, A, Sepanlou, S, Seylani, A, Sha, F, Shahabi, S, Shaikh, M, Shannawaz, M, Shawon, M, Sheikh, A, Sheikhbahaei, S, Shibuya, K, Siabani, S, Silva, D, Singh, J, Skryabin, V, Skryabina, A, Sobaih, B, Stortecky, S, Stranges, S, Tadesse, E, Tarigan, I, Temsah, M, Teuschl, Y, Thrift, A, Tonelli, M, Tovani-Palone, M, Tran, B, Tripathi, M, Tsegaye, G, Ullah, A, Unim, B, Unnikrishnan, B, Vakilian, A, Tahbaz, S, Vasankari, T, Venketasubramanian, N, Vervoort, D, Vo, B, Volovici, V, Vosoughi, K, Vu, G, Vu, L, Wafa, H, Waheed, Y, Wang, Y, Wijeratne, T, Winkler, A, Wolfe, C, Woodward, M, Wu, J, Hanson, S, Xu, X, Yadav, L, Yadollahpour, A, Jabbari, S, Yamagishi, K, Yatsuya, H, Yonemoto, N, Yu, C, Yunusa, I, Zaman, M, Zaman, S, Zamanian, M, Zand, R, Zandifar, A, Zastrozhin, M, Zastrozhina, A, Zhang, Y, Zhang, Z, Zhong, C, Zuniga, Y, Murray, C, Value, Affordability and Sustainability (VALUE), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), and Microbes in Health and Disease (MHD)
- Subjects
Male ,Aging ,030204 cardiovascular system & hematology ,Stroke data ,GUIDELINES ,3124 Neurology and psychiatry ,Body Mass Index ,Global Burden of Disease ,0302 clinical medicine ,RA0421 ,Risk Factors ,Epidemiology ,Strokes ,YOUNG-ADULTS ,Prevalence ,80 and over ,Aetiology ,610 Medicine & health ,Stroke ,POPULATION ,1103 Clinical Sciences, 1109 Neurosciences ,Cause of death ,Aged, 80 and over ,education.field_of_study ,Mortality rate ,Incidence (epidemiology) ,Incidence ,1. No poverty ,Articles ,Hälsovetenskaper ,Middle Aged ,Stroke types ,ddc ,3. Good health ,ISCHEMIC-STROKE ,Income ,Female ,Quality-Adjusted Life Years ,Life Sciences & Biomedicine ,Adult ,medicine.medical_specialty ,GBD ,Population ,Clinical Sciences ,Clinical Neurology ,03 medical and health sciences ,Clinical Research ,MIDDLE-INCOME COUNTRIES ,Health Sciences ,medicine ,Humans ,Risk factor ,education ,GBD 2019 Stroke Collaborators ,Cerebral Hemorrhage ,Aged ,Ischemic Stroke ,Global burden ,Science & Technology ,Neurology & Neurosurgery ,HYPERTENSION ,business.industry ,MORTALITY ,Prevention ,3112 Neurosciences ,Neurosciences ,1103 Clinical Sciences ,SERVICES ,Subarachnoid Hemorrhage ,medicine.disease ,PREVENTION ,Brain Disorders ,Good Health and Well Being ,Attributable risk ,Human medicine ,Neurology (clinical) ,Neurosciences & Neurology ,business ,1109 Neurosciences ,030217 neurology & neurosurgery ,Demography ,2.4 Surveillance and distribution ,RC - Abstract
Background Regularly updated data on stroke and its pathological types, including data on their incidence, prevalence, mortality, disability, risk factors, and epidemiological trends, are important for evidence-based stroke care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) aims to provide a standardised and comprehensive measurement of these metrics at global, regional, and national levels. Methods We applied GBD 2019 analytical tools to calculate stroke incidence, prevalence, mortality, disability-adjusted life-years (DALYs), and the population attributable fraction (PAF) of DALYs (with corresponding 95% uncertainty intervals [UIs]) associated with 19 risk factors, for 204 countries and territories from 1990 to 2019. These estimates were provided for ischaemic stroke, intracerebral haemorrhage, subarachnoid haemorrhage, and all strokes combined, and stratified by sex, age group, and World Bank country income level. Findings In 2019, there were 12·2 million (95% UI 11·0–13·6) incident cases of stroke, 101 million (93·2–111) prevalent cases of stroke, 143 million (133–153) DALYs due to stroke, and 6·55 million (6·00–7·02) deaths from stroke. Globally, stroke remained the second-leading cause of death (11·6% [10·8–12·2] of total deaths) and the third-leading cause of death and disability combined (5·7% [5·1–6·2] of total DALYs) in 2019. From 1990 to 2019, the absolute number of incident strokes increased by 70·0% (67·0–73·0), prevalent strokes increased by 85·0% (83·0–88·0), deaths from stroke increased by 43·0% (31·0–55·0), and DALYs due to stroke increased by 32·0% (22·0–42·0). During the same period, age-standardised rates of stroke incidence decreased by 17·0% (15·0–18·0), mortality decreased by 36·0% (31·0–42·0), prevalence decreased by 6·0% (5·0–7·0), and DALYs decreased by 36·0% (31·0–42·0). However, among people younger than 70 years, prevalence rates increased by 22·0% (21·0–24·0) and incidence rates increased by 15·0% (12·0–18·0). In 2019, the age-standardised stroke-related mortality rate was 3·6 (3·5–3·8) times higher in the World Bank low-income group than in the World Bank high-income group, and the age-standardised stroke-related DALY rate was 3·7 (3·5–3·9) times higher in the low-income group than the high-income group. Ischaemic stroke constituted 62·4% of all incident strokes in 2019 (7·63 million [6·57–8·96]), while intracerebral haemorrhage constituted 27·9% (3·41 million [2·97–3·91]) and subarachnoid haemorrhage constituted 9·7% (1·18 million [1·01–1·39]). In 2019, the five leading risk factors for stroke were high systolic blood pressure (contributing to 79·6 million [67·7–90·8] DALYs or 55·5% [48·2–62·0] of total stroke DALYs), high body-mass index (34·9 million [22·3–48·6] DALYs or 24·3% [15·7–33·2]), high fasting plasma glucose (28·9 million [19·8–41·5] DALYs or 20·2% [13·8–29·1]), ambient particulate matter pollution (28·7 million [23·4–33·4] DALYs or 20·1% [16·6–23·0]), and smoking (25·3 million [22·6–28·2] DALYs or 17·6% [16·4–19·0]). Interpretation The annual number of strokes and deaths due to stroke increased substantially from 1990 to 2019, despite substantial reductions in age-standardised rates, particularly among people older than 70 years. The highest age-standardised stroke-related mortality and DALY rates were in the World Bank low-income group. The fastest-growing risk factor for stroke between 1990 and 2019 was high body-mass index. Without urgent implementation of effective primary prevention strategies, the stroke burden will probably continue to grow across the world, particularly in low-income countries. Funding Bill & Melinda Gates Foundation.
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- 2021
31. Tracking development assistance for health and for COVID-19: a review of development assistance, government, out-of-pocket, and other private spending on health for 204 countries and territories, 1990–2050
- Author
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Junaid Khan, Blake Angell, Marcel Ausloos, Catherine M. Antony, Elham Ehsani-Chimeh, Edgar Denova-Gutiérrez, Kewal Krishan, Mohamed Kamal Mesregah, Arrigo Francesco Giuseppe Cicero, Simona Cătălina Ştefan, Tanuj Kanchan, Maysaa El Sayed Zaki, Mohamed I Hegazy, Richard James Maude, Salman Rawaf, Viktória Szerencsés, Milena Santric-Milicevic, Martin McKee, Reza Rawassizadeh, Anton C Harle, Neda Milevska Kostova, Hamidreza Pazoki Toroudi, Saravanan Muthupandian, Mohammad Hifz Ur Rahman, Hassan Abolhassani, Christine Mpundu-Kaambwa, Atta Abbas Naqvi, John Dube, Habib Benzian, Cristiano Piccinelli, Kedir Hussein Abegaz, Mohammad Khammarnia, Carlo Eduardo Medina-Solís, Tanvir M. Huda, Fakher Rahim, Modhurima Moitra, Valentin Yurievich Skryabin, Emily Joy Callander, David Laith Rawaf, Saeed Shahabi, Mohsen Bayati, Raffaele Palladino, Shahin Soltani, Mohammad Ali Mansournia, Rafael Lozano, Himal Kandel, João Vasco Santos, MA Garcia-Gordillo, Savita Lasrado, Alexey V Breusov, Nicola Luigi Bragazzi, Deepak Dhamnetiya, Mohammad Amin Bahrami, Teroj Abdulrahman Mohamed, Reinhard Busse, Veer Bala Gupta, Ionut Negoi, Xiaochen Dai, Eun-Cheol Park, Trang Huyen Nguyen, Gulrez Shah Azhar, Annie Haakenstad, Asadollah Gholamian, Vafa Rahimi-Movaghar, Subramanian Senthilkumaran, Ismaeel Yunusa, Hubert Amu, G. K. Mini, Francesco Saverio Violante, Michael Abdelmasseh, Yun Jin Kim, Yousef Moradi, Nataliya Foigt, Afshin Maleki, Pavanchand H Shetty, Mesfin Agachew Woldekidan, Ramesh Holla, Mina Anjomshoa, Seyyed Meysam Mousavi, Azeem Majeed, Bright Opoku Ahinkorah, Hassan Magdy Abd El Razek, Avirup Guha, Telma Zahirian Moghadam, Olayinka Stephen Ilesanmi, Alessandro Arrigo, Neda Kianipour, Marcos Roberto Tovani-Palone, Mosiur Rahman, Tomas Y Ferede, Catalina Liliana Andrei, Alaa Makki, Joseph L Dieleman, Shuhei Nomura, Kanwar Hamza Shuja, Ileana Heredia-Pi, Mukhammad David Naimzada, Ali Kazemi Karyani, Chisom Joyqueenet Akunna, Souranshu Chatterjee, Yonas Akalu, Hanadi Al Hamad, Abdollah Mohammadian-Hafshejani, Hayley N Stutzman, Getinet Ayano, Atte Meretoja, Fahad Alanezi, Aravind Thavamani, Sonu Bhaskar, Claudiu Herteliu, Andreea Mirica, Masood Ali Shaikh, Soewarta Kosen, Nelson J. Alvis-Zakzuk, Emma Elizabeth Spurlock, Ferrán Catalá-López, Samath D Dharmaratne, Stany W. Lobo, Alemayehu Hailu, Sebastian Vollmer, Tarik Ahmed Rashid, Sheikh Mohammed Shariful Islam, Lalit Dandona, Farahnaz Joukar, Jacob Olusegun Olusanya, Befikadu Legesse Wubishet, Sezer Kisa, Songhomitra Panda-Jonas, Nasir Umar, Adrian Otoiu, Yonas Getaye Tefera, Harapan Harapan, Ivo Iavicoli, Jakub Morze, Mihajlo Jakovljevic, Nicholas J K Breitborde, Ian E Cogswell, Mehdi Hosseinzadeh, Sadia Bibi, Stefan Kohler, Florian Fischer, Jagdish Khubchandani, Justice Nonvignon, Salah Eddin Karimi, Yousef Khader, Jan-Walter De Neve, Stanislav S. Otstavnov, Ruoyan Tobe-Gai, Tommi Vasankari, Carlos A Castañeda-Orjuela, Nahlah Elkudssiah Ismail, Khezar Hayat, Chythra R Rao, Priya Rathi, Asma Tahir Awan, Jean Jacques Noubiap, Salime Goharinezhad, Ai Koyanagi, Rafael Tabarés-Seisdedos, Angela E Micah, Rakhi Dandona, Jaykaran Charan, Lorainne Tudor Car, Michael R.M. Abrigo, Kenji Shibuya, Aziz Sheikh, B Reshmi, Rovshan Khalilov, Haroon Ahmed, Andrea Werdecker, Alberto Freitas, Tara Ballav Adhikari, Vasily Vlassov, Risky Kusuma Hartono, Leila Keikavoosi-Arani, Gyu Ri Kim, Ana Laura Manda, Carlos Alberto Marrugo Arnedo, Obinna Onwujekwe, Van C. Lansingh, Miklós Szócska, Gelin Xu, Ted R. Miller, Saad M.A. Dahlawi, Till Bärnighausen, Jagadish Rao Padubidri, Bernhard T. Baune, Fatemeh Pashazadeh Kan, Juan Sanabria, Bruno Ramos Nascimento, Stefano Olgiati, Navid Rabiee, Mark G. Shrime, Mayowa O. Owolabi, V. E. Nwatah, Tesleem Kayode Babalola, Ranil Jayawardena, Robert Kaba Alhassan, Takeshi Fukumoto, Lucero Cahuana-Hurtado, Aparna Ichalangod Narayana, Mohammad Ali Sahraian, Atif Amin Baig, Carl Abelardo T. Antonio, Jost B. Jonas, Dian Kusuma, Priyanga Ranasinghe, Mikhail Sergeevich Zastrozhin, Ali Bijani, Arash Ziapour, Seyed Behzad Jazayeri, Francesco Sanmarchi, Seyed Sina Naghibi Irvani, Allen Seylani, Theo Vos, Tuomo J. Meretoja, Delia Hendrie, Mostafa Amini-Rarani, Manthan D Janodia, Sathish Kumar Jayapal, Sorin Hostiuc, Marjan Ajami, Ali Gholamrezanezhad, Muhammad Aqeel, Muhammed Magdy Abd El Razek, Shaun Wen Huey Lee, Rawlance Ndejjo, Maarten J. Postma, Luis Camera, Chhabi Lal Ranabhat, Sadaf G. Sepanlou, Adnan Kisa, Tahira Ashraf, Tudorel Andrei, Mohammad Ali Jahani, Virginia Bodolica, Chuanhua Yu, Moses K. Muriithi, Pascual R. Valdez, Paul S. F. Yip, Demetris Lamnisos, Amir Masoud Rahmani, Hamed Zandian, Anna Aleksandrovna Skryabina, Yeong Yeh Lee, Sana Salehi, Syed Mohamed Aljunid, Kyle E. Simpson, Sami Almustanyir Almustanyir, Bogdan Oancea, Biswa Prakash Nayak, Omid Dadras, Fariborz Mansour-Ghanaei, Turki Alanzi, Mahaveer Golechha, Bach Xuan Tran, Lal B. Rawal, Shoaib Hassan, Rahul R. Zende, Sandhya Neupane Kandel, Martin Amogre Ayanore, Adam E. Berman, Long Khanh Dao Le, Dragos Virgil Davitoiu, Adithi Shetty, Getinet Kassahun, Birhanu Wubale Yirdaw, Usha Ram, Linh Gia Vu, Emilie R Maddison, Yosef Alemayehu, Ali H. Mokdad, Tomislav Mestrovic, Mavra A Riaz, Muhammad Naveed, Koustuv Dalal, Syed Amir Gilani, Reza Malekzadeh, Nikha Bhardwaj, Desta Debalkie Atnafu, Rohollah Kalhor, Naohiro Yonemoto, Ahmad Ghashghaee, Andre M. N. Renzaho, Amadou Barrow, Christopher J L Murray, Budi Aji, Maitreyi Sahu, Sara D Friedman, Konrad Pesudovs, Robert Reiner, Mohammad Rifat Haider, Mustafa Z. Younis, Aidin Abedi, Sanjay Basu, Nancy Fullman, Darrah McCracken, Rajasekaran Koteeswaran, Falk Schwendicke, Ionela-Roxana Glavan, Mohamed H Hassanein, Sindhura Lakshmi Koulmane Laxminarayana, Javad Nazari, Khurshid Alam, Bulat Idrisov, Nelson Alvis-Guzman, Mokhtar Mohammadi, Golnaz Heidari, Asif Hanif, Ghozali Ghozali, Vijay Kumar Chattu, Leila Doshmangir, Simiao Chen, Maha El Tantawi, Stephen S Lim, Bay Vo, Deepak Saxena, Jasvinder A. Singh, Robert Ancuceanu, Yves Miel H Zuniga, Kamal Hezam, Andrew T Olagunju, Sheikh Jamal Hossain, Lindsey E Wallace, Dejana Braithwaite, Sergio I. Prada, Adolfo Martinez-Valle, Brandon Cunningham, Vivek Gupta, Joseph Salama, Rezaul Karim Ripon, Bing-Fang Hwang, Mokhtar Mahdavi, Tamás Joó, Cristiana Abbafati, Behzad Karami Matin, Tushar Garg, Cyrus Alinia, Yingxi Zhao, Richard G. Wamai, Satoshi Ezoe, Anders Larsson, Seyedeh Zahra Masoumi, Arokiasamy Perianayagam, Sharareh Eskandarieh, Maciej Banach, Billingsley Kaambwa, Nader Jahanmehr, Saeed Amini, Foluke Adetola Ojelabi, Nikolay Ivanovich Briko, Samer Hamidi, Gaetano Isola, Tahereh Javaheri, Gbenga A. Kayode, Nikita Otstavnov, Vahid Yazdi-Feyzabadi, David M. Pereira, Mansour Ghafourifard, Saira Afzal, Ravi Prakash Jha, Erkin M. Mirrakhimov, Ahamarshan Jayaraman Nagarajan, Giang Thu Vu, G Anil Kumar, Vahit Yigit, Farshad Farzadfar, Anasthasia Zastrozhina, Shafiu Mohammed, Leticia Avila-Burgos, Nastaran Barati, Morteza Arab-Zozani, Eduardo A. Undurraga, Muktar Beshir Ahmed, Mohamed M. Gad, Mikk Jürisson, Himanshu Khajuria, Anas M. Saad, Mohammad Rabiee, Abdallah M. Samy, Srinivas Goli, Roman Topor-Madry, Golsum Tsakalos, Mariam Molokhia, Biruk Wogayehu Taddele, Mohammad Ali Moni, E S Abhilash, Timur Aripov, Sepideh Ahmadi, Mehdi Sayyah, Jorge Hugo Villafañe, Peter Andras Gaal, Babayemi O Olakunde, Brijesh Sathian, Anayat Ullah, Ritesh G. Menezes, Samad Azari, Ahmed I. Hasaballah, Soosanna Kumary Chattu, Pankaj Bhardwaj, Sanni Yaya, Zhi-Jiang Zhang, Jalal Arabloo, Saif Ullah, Akshaya Srikanth Bhagavathula, Bahram Mohajer, Ekaterina Vladimirovna Glushkova, Vinay Nangia, Shrikant Pawar, Moslem Soofi, Antonio Reis de Sá-Junior, Simon I. Hay, Miloje Savic, 2. Global Burden of Disease 2020 Health Financing Collaborator Network, Cicero AFG, Network, Global Burden of Disease 2020 Health Financing Collaborator, Bill & Melinda Gates Foundation, Micah, A. E., Cogswell, I. E., Cunningham, B., Ezoe, S., Harle, A. C., Maddison, E. R., Mccracken, D., Nomura, S., Simpson, K. E., Stutzman, H. N., Tsakalos, G., Wallace, L. E., Zhao, Y., Zende, R. R., Abbafati, C., Abdelmasseh, M., Abedi, A., Abegaz, K. H., Abhilash, E. S., Abolhassani, H., Abrigo, M. R. M., Adhikari, T. B., Afzal, S., Ahinkorah, B. O., Ahmadi, S., Ahmed, H., Ahmed, M. B., Ahmed Rashid, T., Ajami, M., Aji, B., Akalu, Y., Akunna, C. J., Al Hamad, H., Alam, K., Alanezi, F. M., Alanzi, T. M., Alemayehu, Y., Alhassan, R. K., Alinia, C., Aljunid, S. M., Almustanyir, S. A., Alvis-Guzman, N., Alvis-Zakzuk, N. J., Amini, S., Amini-Rarani, M., Amu, H., Ancuceanu, R., Andrei, C. L., Andrei, T., Angell, B., Anjomshoa, M., Antonio, C. A. T., Antony, C. M., Aqeel, M., Arabloo, J., Arab-Zozani, M., Aripov, T., Arrigo, A., Ashraf, T., Atnafu, D. D., Ausloos, M., Avila-Burgos, L., Awan, A. T., Ayano, G., Ayanore, M. A., Azari, S., Azhar, G. S., Babalola, T. K., Bahrami, M. A., Baig, A. A., Banach, M., Barati, N., Barnighausen, T. W., Barrow, A., Basu, S., Baune, B. T., Bayati, M., Benzian, H., Berman, A. E., Bhagavathula, A. S., Bhardwaj, N., Bhardwaj, P., Bhaskar, S., Bibi, S., Bijani, A., Bodolica, V., Bragazzi, N. L., Braithwaite, D., Breitborde, N. J. K., Breusov, A. V., Briko, N. I., Busse, R., Cahuana-Hurtado, L., Callander, E. J., Camera, L. A., Castaneda-Orjuela, C. A., Catala-Lopez, F., Charan, J., Chatterjee, S., Chattu, S. K., Chattu, V. K., Chen, S., Cicero, A. F. G., Dadras, O., Dahlawi, S. M. A., Dai, X., Dalal, K., Dandona, L., Dandona, R., Davitoiu, D. V., De Neve, J. -W., de Sa-Junior, A. R., Denova-Gutierrez, E., Dhamnetiya, D., Dharmaratne, S. D., Doshmangir, L., Dube, J., Ehsani-Chimeh, E., El Sayed Zaki, M., El Tantawi, M., Eskandarieh, S., Farzadfar, F., Ferede, T. Y., Fischer, F., Foigt, N. A., Freitas, A., Friedman, S. D., Fukumoto, T., Fullman, N., Gaal, P. A., Gad, M. M., Garcia-Gordillo, M. A., Garg, T., Ghafourifard, M., Ghashghaee, A., Gholamian, A., Gholamrezanezhad, A., Ghozali, G., Gilani, S. A., Glavan, I. -R., Glushkova, E. V., Goharinezhad, S., Golechha, M., Goli, S., Guha, A., Gupta, V. B., Gupta, V. K., Haakenstad, A., Haider, M. R., Hailu, A., Hamidi, S., Hanif, A., Harapan, H., Hartono, R. K., Hasaballah, A. I., Hassan, S., Hassanein, M. H., Hayat, K., Hegazy, M. I., Heidari, G., Hendrie, D., Heredia-Pi, I., Herteliu, C., Hezam, K., Holla, R., Hossain, S. J., Hosseinzadeh, M., Hostiuc, S., Huda, T. M., Hwang, B. -F., Iavicoli, I., Idrisov, B., Ilesanmi, O. S., Irvani, S. S. N., Islam, S. M. S., Ismail, N. E., Isola, G., Jahani, M. A., Jahanmehr, N., Jakovljevic, M., Janodia, M. D., Javaheri, T., Jayapal, S. K., Jayawardena, R., Jazayeri, S. B., Jha, R. P., Jonas, J. B., Joo, T., Joukar, F., Jurisson, M., Kaambwa, B., Kalhor, R., Kanchan, T., Kandel, H., Karami Matin, B., Karimi, S. E., Kassahun, G., Kayode, G. A., Kazemi Karyani, A., Keikavoosi-Arani, L., Khader, Y. S., Khajuria, H., Khalilov, R., Khammarnia, M., Khan, J., Khubchandani, J., Kianipour, N., Kim, G. R., Kim, Y. J., Kisa, A., Kisa, S., Kohler, S., Kosen, S., Koteeswaran, R., Koulmane Laxminarayana, S. L., Koyanagi, A., Krishan, K., Kumar, G. A., Kusuma, D., Lamnisos, D., Lansingh, V. C., Larsson, A. O., Lasrado, S., Le, L. K. D., Lee, S. W. H., Lee, Y. Y., Lim, S. S., Lobo, S. W., Lozano, R., Magdy Abd El Razek, H., Magdy Abd El Razek, M., Mahdavi, M. M., Majeed, A., Makki, A., Maleki, A., Malekzadeh, R., Manda, A. L., Mansour-Ghanaei, F., Mansournia, M. A., Marrugo Arnedo, C. A., Martinez-Valle, A., Masoumi, S. Z., Maude, R. J., Mckee, M., Medina-Solis, C. E., Menezes, R. G., Meretoja, A., Meretoja, T. J., Mesregah, M. K., Mestrovic, T., Milevska Kostova, N., Miller, T. R., Mini, G. K., Mirica, A., Mirrakhimov, E. M., Mohajer, B., Mohamed, T. A., Mohammadi, M., Mohammadian-Hafshejani, A., Mohammed, S., Moitra, M., Mokdad, A. H., Molokhia, M., Moni, M. A., Moradi, Y., Morze, J., Mousavi, S. M., Mpundu-Kaambwa, C., Muriithi, M. K., Muthupandian, S., Nagarajan, A. J., Naimzada, M. D., Nangia, V., Naqvi, A. A., Narayana, A. I., Nascimento, B. R., Naveed, M., Nayak, B. P., Nazari, J., Ndejjo, R., Negoi, I., Neupane Kandel, S., Nguyen, T. H., Nonvignon, J., Noubiap, J. J., Nwatah, V. E., Oancea, B., Ojelabi, F. A. O., Olagunju, A. T., Olakunde, B. O., Olgiati, S., Olusanya, J. O., Onwujekwe, O. E., Otoiu, A., Otstavnov, N., Otstavnov, S. S., Owolabi, M. O., Padubidri, J. R., Palladino, R., Panda-Jonas, S., Park, E. -C., Pashazadeh Kan, F., Pawar, S., Pazoki Toroudi, H., Pereira, D. M., Perianayagam, A., Pesudovs, K., Piccinelli, C., Postma, M. J., Prada, S. I., Rabiee, M., Rabiee, N., Rahim, F., Rahimi-Movaghar, V., Rahman, M. H. U., Rahman, M., Rahmani, A. M., Ram, U., Ranabhat, C. L., Ranasinghe, P., Rao, C. R., Rathi, P., Rawaf, D. L., Rawaf, S., Rawal, L., Rawassizadeh, R., Reiner Jr, R. C., Renzaho, A. M. N., Reshmi, B., Riaz, M. A., Ripon, R. K., Saad, A. M., Sahraian, M. A., Sahu, M., Salama, J. S., Salehi, S., Samy, A. M., Sanabria, J., Sanmarchi, F., Santos, J. V., Santric-Milicevic, M. M., Sathian, B., Savic, M., Saxena, D., Sayyah, M., Schwendicke, F., Senthilkumaran, S., Sepanlou, S. G., Seylani, A., Shahabi, S., Shaikh, M. A., Sheikh, A., Shetty, A., Shetty, P. H., Shibuya, K., Shrime, M. G., Shuja, K. H., Singh, J. A., Skryabin, V. Y., Skryabina, A. A., Soltani, S., Soofi, M., Spurlock, E. E., Stefan, S. C., Szerencses, V., Szocska, M., Tabares-Seisdedos, R., Taddele, B. W., Tefera, Y. G., Thavamani, A., Tobe-Gai, R., Topor-Madry, R., Tovani-Palone, M. R., Tran, B. X., Tudor Car, L., Ullah, A., Ullah, S., Umar, N., Undurraga, E. A., Valdez, P. R., Vasankari, T. J., Villafane, J. H., Violante, F. S., Vlassov, V., Vo, B., Vollmer, S., Vos, T., Vu, G. T., Vu, L. G., Wamai, R. G., Werdecker, A., Woldekidan, M. A., Wubishet, B. L., Xu, G., Yaya, S., Yazdi-Feyzabadi, V., Yigit, V., Yip, P., Yirdaw, B. W., Yonemoto, N., Younis, M. Z., Yu, C., Yunusa, I., Zahirian Moghadam, T., Zandian, H., Zastrozhin, M. S., Zastrozhina, A., Zhang, Z. -J., Ziapour, A., Zuniga, Y. M. H., Hay, S. I., Murray, C. J. L., and Dieleman, J. L.
- Subjects
Economic growth ,Financing, Government ,International Cooperation ,HN ,HM ,Global Health ,Gross domestic product ,International Agencies/economics ,0302 clinical medicine ,RA0421 ,Per capita ,Global health ,Healthcare Financing ,11 Medical and Health Sciences ,2. Zero hunger ,COVID 19 ,develompment assistance ,health financing ,projection 1995-250 ,INCOME ,COVID-19 ,Development assistance ,Health financing ,COVID-19/economics ,1. No poverty ,Public Health, Global Health, Social Medicine and Epidemiology ,Articles ,General Medicine ,3. Good health ,Government Programs ,Health Expenditures/statistics & numerical data ,030220 oncology & carcinogenesis ,Transparency (graphic) ,QR180 ,Economic Development ,International development ,Life Sciences & Biomedicine ,medicine.medical_specialty ,Government Programs/economics ,Gross Domestic Product ,Context (language use) ,03 medical and health sciences ,Medicine, General & Internal ,General & Internal Medicine ,medicine ,Humans ,Developing Countries/economics ,Developing Countries ,Government ,Science & Technology ,Public health ,COVID-19, development assistance, global health ,Global Burden of Disease 2020 Health Financing Collaborator Network ,International Agencies ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,Business ,Global Health/economics ,Health Expenditures ,030217 neurology & neurosurgery ,RC ,Financing, Government/economics - Abstract
Background The rapid spread of COVID-19 renewed the focus on how health systems across the globe are financed, especially during public health emergencies. Development assistance is an important source of health financing in many low-income countries, yet little is known about how much of this funding was disbursed for COVID-19. We aimed to put development assistance for health for COVID-19 in the context of broader trends in global health financing, and to estimate total health spending from 1995 to 2050 and development assistance for COVID-19 in 2020. Methods We estimated domestic health spending and development assistance for health to generate total health-sector spending estimates for 204 countries and territories. We leveraged data from the WHO Global Health Expenditure Database to produce estimates of domestic health spending. To generate estimates for development assistance for health, we relied on project-level disbursement data from the major international development agencies' online databases and annual financial statements and reports for information on income sources. To adjust our estimates for 2020 to include disbursements related to COVID-19, we extracted project data on commitments and disbursements from a broader set of databases (because not all of the data sources used to estimate the historical series extend to 2020), including the UN Office of Humanitarian Assistance Financial Tracking Service and the International Aid Transparency Initiative. We reported all the historic and future spending estimates in inflation-adjusted 2020 US$, 2020 US$ per capita, purchasing-power parity-adjusted US$ per capita, and as a proportion of gross domestic product. We used various models to generate future health spending to 2050. Findings In 2019, health spending globally reached $8. 8 trillion (95% uncertainty interval [UI] 8.7-8.8) or $1132 (1119-1143) per person. Spending on health varied within and across income groups and geographical regions. Of this total, $40.4 billion (0.5%, 95% UI 0.5-0.5) was development assistance for health provided to low-income and middle-income countries, which made up 24.6% (UI 24.0-25.1) of total spending in low-income countries. We estimate that $54.8 billion in development assistance for health was disbursed in 2020. Of this, $13.7 billion was targeted toward the COVID-19 health response. $12.3 billion was newly committed and $1.4 billion was repurposed from existing health projects. $3.1 billion (22.4%) of the funds focused on country-level coordination and $2.4 billion (17.9%) was for supply chain and logistics. Only $714.4 million (7.7%) of COVID-19 development assistance for health went to Latin America, despite this region reporting 34.3% of total recorded COVID-19 deaths in low-income or middle-income countries in 2020. Spending on health is expected to rise to $1519 (1448-1591) per person in 2050, although spending across countries is expected to remain varied. Interpretation Global health spending is expected to continue to grow, but remain unequally distributed between countries. We estimate that development organisations substantially increased the amount of development assistance for health provided in 2020. Continued efforts are needed to raise sufficient resources to mitigate the pandemic for the most vulnerable, and to help curtail the pandemic for all. For complete list of authors see http://dx.doi.org/10.1016/S0140-6736(21)01258-7
- Published
- 2021
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