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1. Accumulative magnetic switching of ultra-high-density recording media by circularly polarized light

Author

Takahashi, Y. K., Medapalli, R., Kasai, S., Wang, J., Ishioka, K., Wee, S. H., Hellwig, O., Hono, K., and Fullerton, E. E.

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics, Condensed Matter - Materials Science
Abstract

Manipulation of the magnetization by external energies other than magnetic field, such as spin-polarized current1-4, electric voltage5,6 and circularly polarized light7-11 gives a paradigm shift in magnetic nanodevices. Magnetization control of ferromagnetic materials only by circularly polarized light has received increasing attention both as a fundamental probe of the interactions of light and magnetism but also for future high-density magnetic recording technologies. Here we show that for granular FePt films, designed for ultrahigh-density recording, the optical magnetic switching by circularly polarized light is an accumulative effect from multiple optical pulses. We further show that deterministic switching of high anisotropy materials by the combination of circularly polarized light and modest external magnetic fields, thus revealing a pathway towards technological implementation., Comment: 16 pages, 3 figures + supplementary information

Published
2016
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2. Clinical Characteristics and Therapeutic Outcomes of Metastatic Peritoneal Carcinomatosis in Non-Small-Cell Lung Cancer

Author

Tani T, Nakachi I, Ikemura S, Nukaga S, Ohgino K, Kuroda A, Terai H, Masuzawa K, Shinozaki T, Ishioka K, Funatsu Y, Koh H, Fukunaga K, and Soejima K

Subjects
metastatic peritoneal carcinomatosis, nsclc, egfr, malignant ascites, peritoneal nodule, intraperitoneal dissemination, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Tetsuo Tani,1– 3 Ichiro Nakachi,1,4 Shinnosuke Ikemura,1 Shigenari Nukaga,1,5 Keiko Ohgino,1,6 Aoi Kuroda,1,7 Hideki Terai,1,8 Keita Masuzawa,1,8 Taro Shinozaki,1 Kota Ishioka,1,9 Yohei Funatsu,1,2 Hidefumi Koh,1,2 Koichi Fukunaga,1 Kenzo Soejima1,10 On behalf of the Keio Lung Oncology Group (KLOG)1Department of Medicine, Keio University School of Medicine, Tokyo, Japan; 2Department of Internal Medicine, Tachikawa Hospital, Tokyo, Japan; 3Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA; 4Department of Internal Medicine, Saiseikai Utsunomiya Hospital, Utsunomiya, Tochigi, Japan; 5Department of Respiratory Medicine, National Hospital Organization Tokyo Medical Center, Tokyo, Japan; 6Department of Pulmonary Medicine, Kawasaki Municipal Hospital, Kawasaki, Kanagawa, Japan; 7Department of Respiratory Medicine, Tokyo Dental College Ichikawa General Hospital, Chiba, Japan; 8Department of Pulmonary Medicine, Kitasato University Kitasato Institute Hospital, Tokyo, Japan; 9Department of Medicine, Tokyo Saiseikai Central Hospital, Tokyo, Japan; 10Clinical and Translational Research Center, Keio University Hospital, Tokyo, JapanCorrespondence: Ichiro NakachiDepartment of Internal Medicine, Saiseikai Utsunomiya Hospital, 911-1 Takebayashimachi, Utsunomiya, Tochigi, 321-0974, JapanTel +81- 28-626-5500Fax +81- 28-626-5594Email nichiro4747@gmail.comBackground: Metastatic peritoneal carcinomatosis (MPC) is not common in patients with non-small cell lung cancer (NSCLC), and the clinical characteristics and treatment outcomes are still unclear.Patients and Methods: We recruited 46 NSCLC patients with MPC at Keio University and affiliated hospitals (Keio Lung Oncology Group) between January 2011 and December 2017, then retrospectively investigated their clinical characteristics and the impact of treatment interventions on their survival.Results: The profile of histological subtype was predominantly adenocarcinoma and 15 patients harbored driver oncogenes. Univariate and multivariate analysis demonstrated that performance status and the presence of a driver oncogene were significantly associated with the prolonged overall survival (OS). Regarding treatment, the median OS in the treatment group (9.3 months) was significantly longer than in the best supportive care group (1.3 months) (P < 0.0001).Conclusion: The prognosis of MPC in NSCLC patients who receive only the best supportive care is poor, but therapeutic intervention may improve prognosis.Keywords: metastatic peritoneal carcinomatosis, NSCLC, EGFR, malignant ascites, peritoneal nodule, intraperitoneal dissemination

Published
2021

5. Selective coupling of coherent optical phonons in YBa2Cu3O7 with electronic transitions

Author

Ishioka, K., Pashkin, O., Bernhard, C., Petek, H., Yao, X., and Demsar, J.

Abstract

We investigate coherent lattice dynamics in optimally doped YBa2Cu3O7−δ driven by ultrashort (∼ 12 fs) near infrared (NIR) and near ultraviolet (NUV) pulses. Transient reflectivity experiments, performed at room temperature and under moderate (

Published
2023

6. Femtosecond Time-resolved X-ray Diffraction for Laser-excited CdTe Crystal

Author

Hironaka, Y., Irisawa, J., Saitoh, J., Kondo, K., Ishioka, K., Kitajima, K., Nakamura, K. G., Rhodes, William T., editor, Adibi, Ali, editor, Asakura, Toshimitsu, editor, Hänsch, Theodor W., editor, Kamiya, Takeshi, editor, Krausz, Ferenc, editor, Monemar, Bo, editor, Venghaus, Herbert, editor, Weber, Horst, editor, Weinfurter, Harald, editor, Watanabe, Shuntaro, editor, and Midorikawa, Katsumi, editor

Published
2007
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11. Measures of insulin sensitivity, leptin, and adiponectin concentrations in cats in diabetic remission compared to healthy control cats

Author

Gottlieb, S., Rand, J.S., Ishioka, K., Dias, D.A., Boughton, B.A., Roessner, U., Ramadan, Z., Anderson, S.T., Gottlieb, S., Rand, J.S., Ishioka, K., Dias, D.A., Boughton, B.A., Roessner, U., Ramadan, Z., and Anderson, S.T.

Abstract

Objectives: Firstly, to compare differences in insulin, adiponectin, leptin, and measures of insulin sensitivity between diabetic cats in remission and healthy control cats, and determine whether these are predictors of diabetic relapse. Secondly, to determine if these hormones are associated with serum metabolites known to differ between groups. Thirdly, if any of the hormonal or identified metabolites are associated with measures of insulin sensitivity. Animals: Twenty cats in diabetic remission for a median of 101 days, and 21 healthy matched control cats. Methods: A casual blood glucose measured on admission to the clinic. Following a 24 h fast, a fasted blood glucose was measured, and blood sample taken for hormone (i.e., insulin, leptin, and adiponectin) and untargeted metabolomic (GC-MS and LC-MS) analysis. A simplified IVGGT (1 g glucose/kg) was performed 3 h later. Cats were monitored for diabetes relapse for at least 9 months (270 days). Results: Cats in diabetic remission had significantly higher serum glucose and insulin concentrations, and decreased insulin sensitivity as indicated by an increase in HOMA and decrease in QUICKI and Bennett indices. Leptin was significantly increased, but there was no difference in adiponectin (or body condition score). Several significant correlations were found between insulin sensitivity indices, leptin, and serum metabolites identified as significantly different between remission and control cats. No metabolites were significantly correlated with adiponectin. No predictors of relapse were identified in this study. Conclusion and clinical importance: Insulin resistance, an underlying factor in diabetic cats, persists in diabetic remission. Cats in remission should be managed to avoid further exacerbating insulin resistance.

Published
2022

12. Measures of insulin sensitivity, leptin, and adiponectin concentrations in cats in diabetic remission compared to healthy control cats

Author

Gottlieb, S, Rand, JS, Ishioka, K, Dias, DA, Boughton, BA, Roessner, U, Ramadan, Z, Anderson, ST, Gottlieb, S, Rand, JS, Ishioka, K, Dias, DA, Boughton, BA, Roessner, U, Ramadan, Z, and Anderson, ST

Abstract

OBJECTIVES: Firstly, to compare differences in insulin, adiponectin, leptin, and measures of insulin sensitivity between diabetic cats in remission and healthy control cats, and determine whether these are predictors of diabetic relapse. Secondly, to determine if these hormones are associated with serum metabolites known to differ between groups. Thirdly, if any of the hormonal or identified metabolites are associated with measures of insulin sensitivity. ANIMALS: Twenty cats in diabetic remission for a median of 101 days, and 21 healthy matched control cats. METHODS: A casual blood glucose measured on admission to the clinic. Following a 24 h fast, a fasted blood glucose was measured, and blood sample taken for hormone (i.e., insulin, leptin, and adiponectin) and untargeted metabolomic (GC-MS and LC-MS) analysis. A simplified IVGGT (1 g glucose/kg) was performed 3 h later. Cats were monitored for diabetes relapse for at least 9 months (270 days). RESULTS: Cats in diabetic remission had significantly higher serum glucose and insulin concentrations, and decreased insulin sensitivity as indicated by an increase in HOMA and decrease in QUICKI and Bennett indices. Leptin was significantly increased, but there was no difference in adiponectin (or body condition score). Several significant correlations were found between insulin sensitivity indices, leptin, and serum metabolites identified as significantly different between remission and control cats. No metabolites were significantly correlated with adiponectin. No predictors of relapse were identified in this study. CONCLUSION AND CLINICAL IMPORTANCE: Insulin resistance, an underlying factor in diabetic cats, persists in diabetic remission. Cats in remission should be managed to avoid further exacerbating insulin resistance.

Published
2022

16. Crystal structure and metallization mechanism of the pi-radical metal TED (vol 11, pg 11699, 2020)

Author

Kobayashi, Y, Hirata, K, Hood, SN, Yang, H, Walsh, A, Matsushita, Y, and Ishioka, K

Subjects
Chemistry, Science & Technology, Chemistry, Multidisciplinary, Physical Sciences, 03 Chemical Sciences
Abstract

Correction for ‘Crystal structure and metallization mechanism of the π-radical metal TED’ by Yuka Kobayashi et al., Chem. Sci., 2020, DOI: 10.1039/d0sc03521a.

Published
2020

33. Dopant dependence on passivation and reactivation of carrier after hydrogenation

Author

Fukata, N., Sato, S., Morihiro, H., Murakami, K., Ishioka, K., Kitajima, M., and Hishita, S.

Subjects
Hydrogenation -- Research, Semiconductor doping -- Methods, Boron -- Chemical properties, Phosphorus -- Chemical properties, Physics
Abstract

The B- or P-doped silicon (Si) crystals, treated with high concentration of H, are studied to analyze the dopant dependence of such complexes on passivation and reactivation of carrier after hydrogenation. The difference in the reactivation process for the p-type and n-type specimens is found to be basically because of the formation of H-related defects based on the stable sites of the hydrogen (H) atoms.

Published
2007

44. Accumulative Magnetic Switching of Ultrahigh-Density Recording Media by Circularly Polarized Light

Author

Takahashi, Y. K., Medapalli, R., Kasai, S., Wang, J., Ishioka, K., Wee, S. H., Hellwig, O., Hono, K., and Fullerton, E. E.

Subjects
Materials science, business.industry, Optoelectronics, Recording media, business, Circular polarization, Magnetic switching
Abstract

Magnetization control of ferromagnetic materials only by circularly polarized light has received increasing attention both as a fundamental probe of the interactions of light and magnetism but also for future highdensity magnetic recording technologies. Here we show that for granular FePt films designed for ultrahighdensity magnetic recording, the optical magnetic switching by circularly polarized light is an accumulative effect from multiple optical pulses. The measured results can be reproduced by a simple statistical model where the probability of switching a grain depends on the helicity of the optical pulses.We further show the deterministic switching of high-anisotropy materials by the combination of circularly polarized light and modest external magnetic fields, thus, revealing a pathway towards technological implementation.

Published
2017
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