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Background: Focused assessment with sonography for trauma (FAST) is useful for detecting hemoperitoneum \n(HE) in trauma patients in the emergency room (ER), but, patients’condition cannot be \nevaluated adequately by FAST alone. CT is useful for the diagnosis of multiple trauma, but has certain \ndrawbacks. We evaluated the utility of mutidetector computed tomography(MDCT) as the initial tool \nfor proper diagnosis and treatment planning of multiple trauma patients. Method: We retrospectively \nanalyzed 128 cases treated in ER of Gunma University Hospital between April 1, 2005 and December 31, \n2006, and they were hospital patients were hospitalized with blunt multiple trauma. We analyzed the \nsensitivity, specificity, and accuracy of FAST, compiled MDCT finding, lifesaving treatment, and \noutcome. Result: Eight patients were FAST positive, and 7 of the 8 were scanned by MDCT. There \nwere 120 patients were FAST negative patients, 23 of the 120 were MDCT-negative, despite visceral \ninjury, however 9 of the 120 had visceral injury by MDCT findings. Damage control surgery without \nMDCT was performed in one case, but the patient died after surgery. Six of the patients in the \nHE-positive group had really HE. One of the 6 died while a waiting surgery, transcatheter arterial \nembolization (TAE) was performed in three patients, and one person out of the 3 died. The course of \nthe remaining 2 patients was monitored, and they are alive. A patient in the HE-negative group with \nbladder rupture required surgery. There were 120 patients in the FAST-negative group. One of the 6 \npatients in the HE-positive subgroup died while a waiting surgery. One patient required chest and \npericardial drainage. TAE was performed in 2 patients, and the remaining 6 were monitored and are \nalive. There were 23 FAST-negative patients patients who had visceral injury. Five of them required \nchest drainage, one received TAE, 17 were monitored, and all of the 23 are alive. There were 14 cases \nof pelvic fracture alone, and all of them were FAST-negative. One patient required surgery for open \nfemoral fracture, TAE was performed in three, 10 monitored, all 14 are alive. Only one patient \ndeveloped shock during MDCT. The others underwent scanning safely. Conclusion: MDCT is a \nbetter tool for the diagnosis of blunt multiple trauma of the trunk than CT, because the scanning time\nis shorter.