10 results on '"Ishida IM"'
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2. Does the 40-Hz auditory steady-state response show the binaural masking level difference?
- Author
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Ishida IM and Stapells DR
- Published
- 2009
- Full Text
- View/download PDF
3. Vestibular aqueduct in sudden sensorineural hearing loss.
- Author
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Sugiura M, Naganawa S, Ishida IM, Teranishi M, Nakata S, Yoshida T, and Nakashima T
- Published
- 2008
- Full Text
- View/download PDF
4. Infant Cortical Auditory Evoked Potentials to Lateralized Noise Shifts Produced by Changes in Interaural Time Difference.
- Author
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Small SA, Ishida IM, and Stapells DR
- Subjects
- Adult, Electroencephalography, Female, Humans, Infant, Male, Middle Aged, Noise, Time Factors, Young Adult, Auditory Cortex physiology, Child Development, Evoked Potentials, Auditory physiology, Sound Localization physiology
- Abstract
Objectives: Newborns reliably orient to sound location soon after birth; by age 1 month this orienting disappears until after age 4 months. It has been suggested that orienting by the newborn reflects subcortical-mediated reflexes, which are suppressed by age 1 month; reappearance of orienting then occurs after age 4 months with maturation of cortical mechanisms of sound localization. In the present study, we assess auditory lateralization in young infants (and adults) by recording slow cortical auditory evoked potentials to lateralization shifts in dichotic noise produced by changes in interaural time difference (ITD)., Design: Fifteen normal infants aged under 4 months (mean = 10.7 weeks) had cortical auditory evoked potentials assessed in response to (1) diotic "onset" noise bursts (0 msec ITD) and (2) shifts in continuous lateralized noise (75 dB SPL) produced by ITD shifts of 0.5, 0.8, 1, 2, 4, and 8 msec. Shifts alternated between ears occurred every 2 sec. Stimuli were presented using insert earphones; infants slept during recordings. For comparison, similar recordings were obtained in 11 normal-hearing, awake, adults. Additionally, "control" recordings to the ITD-shift stimuli presented to only one ear were obtained in the adults., Results: Similar to previous research, adults showed clear N1-P2 responses to the lateralization shifts (ITD 0.5 to 2.0 msec). Responses decreased for longer ITD shifts, with no adult responses to the 8-msec ITD shift. N1 latencies to ITD-shift stimuli were 28 to 34 msec longer than to the onset stimuli. No responses were seen in the control conditions when ITD-shift stimuli were presented to only one ear (confirming the binaural nature of the ITD-shift responses). All infants showed P2 responses to one or more of the ITD-shift stimuli up to ±1 msec; compared with adults, infants showed larger amplitude decreases and fewer responses to longer ITD-shift stimuli. As was seen with the adult responses, infant response (P2) latencies to ITD shifts were longer compared with their responses to the onset stimuli; however, these increases, 32 to 78 msec, were significantly longer than those seen in the adults., Conclusions: Young infants (even as young as 5 weeks) show clear evidence of auditory cortical responsivity to lateralization shifts produced by changes in the ITD of continuous noise, indicating that they have the capacity to process binaural ITD timing cues well before the age of 4 months. Further research is required to determine whether the larger latency increase in infants for ITD-shift stimuli (relative to the onset stimuli) and the greater effect of longer ITD shifts on response presence and amplitude in infants reflects immaturity of lateralization processing and/or reduced responses recorded during sleep. Slow cortical auditory evoked potentials elicited to lateralization shifts in dichotic noise provide a method to investigate binaural hearing processes in young children with normal or impaired hearing.
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- 2017
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- View/download PDF
5. Multiple-ASSR Interactions in Adults with Sensorineural Hearing Loss.
- Author
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Ishida IM and Stapells DR
- Abstract
The multiple auditory steady-state response (multiple-ASSR) technique, where thresholds for up to 8 frequencies (4 in each ear) are obtained simultaneously, is currently of great interest for audiometric assessment of infants. Although threshold estimates using the multiple-ASSR appear to be reasonably accurate, it is not currently known whether it is more efficient to use multiple stimuli or single stimuli when testing individuals with sensorineural hearing loss (SNHL). The current study investigated the effect of single versus multiple simultaneous stimuli on the 80- and 40-Hz ASSRs in adults with normal hearing or SNHL. Results showed significant interactions (i.e., decreased amplitudes) for both ASSRs going from single to multiple stimuli in one ear. Going from multiple one ear to multiple two ears did not further reduce the amplitude of the 80-Hz ASSR. At the 40-Hz rate, however, there was a further amplitude decrease going from one-ear multiple to two-ear multiple stimuli. Importantly, these interactions did not differ between the normal-hearing and SNHL groups. Although supportive of the multiple-ASSR technique, there are likely situations where it is more efficient to use single stimuli. Future studies are required to assess these interactions in infants with varying degrees and configurations of hearing loss.
- Published
- 2012
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6. Multiple auditory steady state response thresholds to bone conduction stimuli in adults with normal and elevated thresholds.
- Author
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Ishida IM, Cuthbert BP, and Stapells DR
- Subjects
- Adult, Diagnosis, Differential, Female, Hearing Loss physiopathology, Hearing Loss, Conductive diagnosis, Hearing Loss, Conductive physiopathology, Hearing Loss, Mixed Conductive-Sensorineural diagnosis, Hearing Loss, Mixed Conductive-Sensorineural physiopathology, Hearing Loss, Sensorineural diagnosis, Hearing Loss, Sensorineural physiopathology, Humans, Male, Middle Aged, Perceptual Masking physiology, Reference Values, Young Adult, Auditory Threshold physiology, Bone Conduction physiology, Diagnostic Techniques, Otological standards, Hearing Loss diagnosis
- Abstract
Objective: Auditory steady state responses (ASSRs) to multiple air conduction (AC) stimuli modulated at ∼80 Hz have been shown to provide reasonable estimates of the behavioral audiogram. To distinguish the type of hearing loss (i.e., conductive, sensorineural, or mixed), bone conduction (BC) results are necessary. There are few BC-ASSR data, especially for individuals with hearing loss. The present studies aimed to (1) determine multiple ASSR thresholds to BC stimuli in adults with normal hearing, masker-simulated hearing loss, and sensorineural hearing loss (SNHL) and (2) determine how well BC-ASSR distinguishes normal versus elevated thresholds to BC stimuli in adults with normal hearing or SNHL., Design: Multiple ASSR and behavioral thresholds for BC stimuli were determined in two studies. Study A assessed 16 normal-hearing adults with relatively flat threshold elevations produced by 50, 60, and 70 dB SPL AC masking noise, as well as no masking. Study B assessed 10 adults with normal hearing and 40 adults with SNHL. In both studies, the multiple (500 to 4000 Hz) ASSR stimuli were modulated between 77 and 101 Hz and varied in intensity from 0 to 50 dB HL in 10-dB steps. Stimuli were presented using a B71 bone oscillator held on the temporal bone by an elastic band while participants relaxed or slept., Results: Study A: Correlations (r) between behavioral and ASSR thresholds for all conditions combined were 0.77, 0.87, 0.90, and 0.87 for 500, 1000, 2000, and 4000 Hz, respectively. ASSR minus behavioral threshold difference scores for all frequencies combined for the no-masker, 50, 60, and 70 dB SPL masker conditions were 14.3 ± 9.2, 12.1 ± 10.4, 12.7 ± 7.7, and 11.4 ± 8.1 dB, respectively. Study B: The difference scores for 500, 1000, 2000, and 4000 Hz were, on average, 15.7 ± 12.3, 10.3 ± 10.7, 9.7 ± 10.3, and 5.7 ± 7.9 dB, respectively, with correlations of 0.73, 0.84, 0.87, and 0.94 for the normal-hearing and SNHL groups combined. The ASSR minus behavioral difference scores were significantly larger for 500 Hz and significantly smaller for 4000 Hz compared with 1000 and 2000 Hz. Across all frequencies, the BC-ASSR correctly classified 89% of thresholds as "normal" or "elevated" (92% correct for 1000, 2000, and 4000 Hz)., Conclusions: The threshold difference scores and correlations in individuals with SNHL are similar to those in normal listeners with simulated SNHL. These difference scores are also similar to those shown by previous studies for the AC-ASSR in individuals with SNHL, at least for 1000 to 4000 Hz. The BC-ASSR provides a reasonably good estimate of BC behavioral threshold in adults, especially between 1000 and 4000 Hz. Further research is required in infants with hearing loss.
- Published
- 2011
- Full Text
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7. Effect of an enlarged endolymphatic duct on bone conduction threshold.
- Author
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Sato E, Sugiura M, Naganawa S, Yoshino T, Mizuno T, Otake H, Ishida IM, and Nakashima T
- Abstract
An enlarged endolymphatic duct and sac (EDS) that makes contact with the cerebrospinal fluid–dural interface plays an important role in the pathway of bone conduction and enhances bone conduction at lower frequencies. Objectives. We investigated whether the bone conduction threshold was improved when the EDS was enlarged. Subjects and methods. Twenty-three patients (46 ears) with large vestibular aqueducts underwent standard pure tone audiometry (PTA) and magnetic resonance imaging (MRI) to investigate the relation between the diameter of the endolymphatic duct (ED) and the air or bone conduction threshold. We also investigated the relation between the volume of the EDS and the air or bone conduction threshold. Results. All ears had a mixed type hearing loss. The air–bone gaps were significantly larger at 250 and 500 Hz than at higher frequencies. The bone conduction thresholds were significantly lower at 250 Hz and 1000 Hz when the diameter of the ED was large, whereas there was no relation between the diameter of the ED and the air conduction threshold. In addition, there was no correlation between the volume of the EDS and air or bone conduction thresholds.
- Published
- 2008
- Full Text
- View/download PDF
8. Otoacoustic emissions, ear fullness and tinnitus in the recovery course of sudden deafness.
- Author
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Ishida IM, Sugiura M, Teranishi M, Katayama N, and Nakashima T
- Subjects
- Adenosine Triphosphate therapeutic use, Adolescent, Adult, Ear Diseases drug therapy, Female, Hearing Loss, Sudden drug therapy, Humans, Male, Middle Aged, Prognosis, Sensation Disorders drug therapy, Treatment Outcome, Vitamin B Complex therapeutic use, Audiometry, Pure-Tone, Auditory Threshold physiology, Ear Diseases physiopathology, Hearing Loss, Sudden physiopathology, Otoacoustic Emissions, Spontaneous physiology, Sensation Disorders physiopathology, Tinnitus physiopathology
- Abstract
Objective: This study aimed to investigate how the symptoms of ear fullness, tinnitus and otoacoustic emissions (OAE) change in relation to the recovery course of pure tone audiometry thresholds (PTA) in sudden deafness (SD)., Methods: This study analyzed follow-up data on ear fullness, tinnitus and otoacoustic emissions of eight SD patients with good hearing improvement (Group A) and eight SD patients with poor hearing improvement (Group B) in an attempt to elucidate the behavior of these symptoms in their recovery course. This study was done until there was no change in the PTA for more than 1 week and hearing recovery was no longer expected., Results: All patients from both groups had ear fullness and tinnitus in association with the onset of SD. However, these symptoms improved only in Group A. showing a significant relationship between PTA recovery and the improvement of ear fullness annoyance (P<0.05), presence of tinnitus (P<0.01), improvement in tinnitus loudness (P<0.01) and in tinnitus annoyance (P<0.01). No patients (Group A or B) had OAE responses at their first examination. In Group A, OAE responses appeared simultaneously with improvement of hearing levels in five patients (63%) and it appeared later than hearing levels improvement in the other three patients (37%) from Group A. No patient from Group B showed OAE response on follow-up., Conclusion: SD patients with good hearing improvement (Group A) tended to have OAE responses and the sensations of the ear fullness and tinnitus improved almost simultaneously with hearing level improvement. Their PTA improvement occurred primarily in the low to mid frequencies, with high frequencies showing less recovery. When hearing recovery was not full, OAEs did not reappear for these frequencies. Patients with poor hearing improvement tended to have absent OAEs and persistent ear fullness and tinnitus.
- Published
- 2008
- Full Text
- View/download PDF
9. Cochlear modiolus and lateral semicircular canal in sudden deafness.
- Author
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Ishida IM, Sugiura M, Naganawa S, Teranishi M, and Nakashima T
- Subjects
- Adolescent, Adult, Aged, Audiometry, Pure-Tone, Cochlea physiopathology, Female, Follow-Up Studies, Hearing Loss, Sensorineural complications, Hearing Loss, Sensorineural pathology, Hearing Loss, Sensorineural physiopathology, Hearing Loss, Sudden etiology, Hearing Loss, Sudden physiopathology, Humans, Male, Middle Aged, Prognosis, Retrospective Studies, Semicircular Canals physiopathology, Vertigo complications, Vertigo pathology, Vertigo physiopathology, Cochlea pathology, Hearing Loss, Sudden diagnosis, Magnetic Resonance Imaging methods, Semicircular Canals pathology
- Abstract
Conclusion: This study demonstrated that precise analysis shows that the inner ear shape in sudden deafness (SD) is different from that in controls in that the fluid-filled area of SD labyrinths is significantly larger than that of controls. Reduced cochlear modiolus area and inner area of the lateral semicircular canal (LSCC) may be associated with insufficient maturation of the inner ear., Objective: The aim of this study was to quantify the morphologies of the cochlea and LSCC using magnetic resonance imaging (MRI) and to evaluate their relationships with clinical symptoms in SD., Subjects and Methods: Twenty-six unilateral SD patients with vertigo, 26 unilateral SD patients without vertigo and a matched control group without hearing loss were studied. The areas of cochlear modioli and LSCCs were traced on the MRI console and compared between SD patients with or without vertigo and control subjects. The ratio of the LSCC fluid-filled area to the total LSCC area was used to index the degree of dysplasia., Results: The cochlear modiolus area was significantly less in SD ears (4.1+/-0.2 mm2) than in controls (4.3+/-0.4 mm2). The LSCC inner area was significantly less in SD ears (6.9+/-1.7 mm2) than in controls (9.1+/-1.8 mm2). These results suggest that the fluid-filled area of SD labyrinths is significantly larger than controls. Morphology did not differ between affected and contralateral sides or between ears with or without vertigo in SD patients.
- Published
- 2007
- Full Text
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10. Lateral semicircular canal and vertigo in patients with large vestibular aqueduct syndrome.
- Author
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Ishida IM, Sugiura M, Nakashima T, Naganawa S, Sato E, Sugiura J, and Yoshino T
- Subjects
- Adolescent, Adult, Case-Control Studies, Child, Endolymphatic Duct pathology, Endolymphatic Sac pathology, Female, Follow-Up Studies, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Multivariate Analysis, Mutation, Missense, Retrospective Studies, Syndrome, Vestibular Diseases genetics, Vestibular Diseases physiopathology, Semicircular Canals pathology, Vertigo etiology, Vestibular Aqueduct pathology, Vestibular Diseases pathology
- Abstract
Objective: To evaluate the hypothesis that there are differences in the morphology of the lateral semicircular canal (LSCC) between patients with large vestibular aqueduct syndrome (LVAS) and control subjects and to investigate the clinical implications of these differences., Study Design: Retrospective case review., Setting: Tertiary referral center., Patients: Nine patients (two male patients and seven female patients; age range, 8-54 yr) with LVAS (one patient had unilateral LVAS, and eight patients had bilateral LVAS). Five patients had vertigo, and four patients, including the one with unilateral LVAS, did not have vertigo., Main Outcome Measures: The area of the LSCC was traced on the magnetic resonance imaging console and compared between LVAS patients and 12 control subjects who did not have sensorineural hearing loss. The LSCC fluid-containing area was divided by the sum of the LSCC inner area and the LSCC fluid-containing area for evaluation of the degree of the LSCC dysplasia., Results: The LSCC fluid-containing ratio was significantly larger in LVAS patients than in control subjects. Moreover, the LSCC fluid-containing ratio was significantly larger in the eight ears with vertigo than in the nine ears without vertigo. There was no relationship between hearing level and the LSCC fluid-containing ratio., Conclusion: Patients with LVAS may have disturbed morphogenesis of both membranous and bony labyrinths. Our results reveal that the morphology of semicircular canals is clinically associated with vertigo.
- Published
- 2006
- Full Text
- View/download PDF
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