1. Functional Outcome after Mechanical Thrombectomy with or without Previous Thrombolysis
- Author
-
Alberto Fior, Ana Luísa Papoila, Marta Alves, João Gilberto Mendes dos Reis, Ana Paiva Nunes, Manuel Machado, and Isabel Fragata
- Subjects
Male ,Time Factors ,Databases, Factual ,Ischemic Stroke / physiopathology ,medicine.medical_treatment ,HSJ UCV ,Stroke onset ,Thrombectomy* / adverse effects ,Disability Evaluation ,0302 clinical medicine ,Risk Factors ,Thrombolytic Therapy ,Infusions, Intravenous ,Stroke ,Thrombectomy ,Aged, 80 and over ,Ischemic Stroke / therapy ,Standard treatment ,Rehabilitation ,Thrombolysis ,Middle Aged ,Combined Modality Therapy ,medicine.anatomical_structure ,Treatment Outcome ,Anesthesia ,Thrombolytic Therapy* / adverse effects ,Female ,Cardiology and Cardiovascular Medicine ,Fibrinolytic Agents / administration & dosage ,CHLC CINV ,Time-to-Treatment ,03 medical and health sciences ,Fibrinolytic Agents ,medicine ,Ischemic Stroke / diagnosis ,Humans ,Ischemic Stroke ,Aged ,Retrospective Studies ,Groin ,business.industry ,Recovery of Function ,medicine.disease ,Mechanical thrombectomy ,Functional Status ,Intravenous therapy ,Surgery ,Neurology (clinical) ,business ,030217 neurology & neurosurgery ,Large vessel occlusion ,Fibrinolytic Agents / adverse effects - Abstract
Introduction: Combined intravenous therapy (IVT) and mechanical thrombectomy (MT) is the standard treatment for acute ischemic stroke (AIS) with large vessel occlusion (LVO). However, the use of IVT before MT is recently being questioned. Objectives: To compare patients treated with IVT before MT with those treated with MT alone, in a real-world scenario. Methods: Retrospective analysis of AIS patients with LVO of the anterior circulation who underwent MT, with or without previous IVT, between 2016 and 2018. Results: A total of 524 patients were included (347 submitted to IVT+MT; 177 to MT alone). No differences between groups were found except for a higher time from stroke onset to CT and to groin puncture in the MT group (297.5 min vs 115.0 min and 394.0 min vs 250.0 min respectively, p < 0.001). Multivariable analysis showed that age
- Published
- 2021