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4 results on '"Isabel García-Moreno M"'

3. Tailoring the inhibitory versus chaperoning behavior of amphiphilic sp-iminosugar glycomimetics targeting β-glucocerebrosidase: From micromolar to picomolar chaperones for Gaucher disease

Author

Garcia Fernandez, Jose M., primary, Mena-Barragán, Teresa, additional, Isabel García-Moreno, M., additional, Sevšek, Alev, additional, Okazaki, Tetsuya, additional, Nanba, Eiji, additional, Higaki, Katsumi, additional, Martin, Nathaniel I., additional, Pieters, Roland J., additional, Mellet, Carmen Ortiz, additional, and Suzuki, Yoshiyuki, additional

Published
2019
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4. Intramolecular Benzyl Protection Delivery:  A Practical Synthesis of DMDP and DGDP from d-Fructose

Author

Isabel García-Moreno, M., Aguilar, Matilde, Ortiz Mellet, Carmen, and M. García Fernández, José

Abstract

A two-step protection of 1,2-diols as the corresponding o-xylylene cyclic ethers, involving an intramolecular ring-closing O-benzylation reaction, has been developed to overcome the problems associated to regioselective benzylation reactions. The strategy has been applied to the high-yielding synthesis of the pyrrolidine glycosidase inhibitors DMDP and DGDP.

Published
2006

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