Search

Introduction: Renal Cell Carcinoma (RCC), a highly vascular tumor may present with rare metastasis at initial presentation. Synchronous breast metastasis from clear cell renal cell carcinoma is very rare and correlates with poor prognosis. In absence of any renal complaints, a breast lump can mimic a primary breast carcinoma or benign breast disease. A 55-year-old fema Case History: le, presented with a swelling in the right breast. Physical examination was suggestive of a benign swelling in view of well-dened margins, no lymphadenopathy, no skin changes. Fine needle aspiration cytology was done twice and was inconclusive. Tru-Cut biopsy revealed metastatic RCC. Mammography showed BIRADS-IV lesion and PET-CT revealed oligometastatic disease with breast and a small solitary lung metastasis. The patient underwent simultaneous right cytoreductive nephrectomy and lumpectomy. Early detection and surgical resecti Conclusion: on of limited metastatic disease is important, as the treatment instituted at an earlier stage when it is amenable to surgical resection improves the survival considerably

Background: Renal cell carcinoma with isolated metastasis to the parotid gland is extremely rare. Slow growth, low level of suspicion and negative Fine needle aspiration cytology (FNAC) often delay the diagnosis. A high level of suspicion of metastatic disease from a specic site is important, otherwise can be missed for a benign swelling leading to delayed treatment and poorer prognosis. A 59-year-old Case presentation: male presented with a swelling in the right preauricular area 5 years post right radical nephrectomy for right renal cell carcinoma (RCC). The examination was suggestive of a benign swelling. FNAC was done twice, which was inconclusive. A Tru-cut biopsy of the lesion revealed metastatic RCC. MRI revealed a dumbbell type of tumor extending deep into the gland and encasing vessels. PET-CT was negative for metastasis to the rest of the body. The patient received targeted therapy followed by radiation therapy with imaging showing non-progression of the disease. Conclusion: Metastatic disease should be considered whenever a parotid mass is detected in patients with an RCC history. Examination ndings can be misleading; hence dedicated imaging is critical. Small parotid metastasis can be cured with surgery. A combination of chemotherapy and radiation therapy can palliate the unresectable disease.

We report the effect of thickness on the structural, morphological, transport and magnetic properties of perovskite oxide La 0.85 Te 0.15 MnO 3 thin films grown on LaAlO 3 (001) single crystal substrate by pulsed laser deposition. We have observed that the transport and magnetic properties of the films depend on the film thickness, surface morphology, and epitaxial strain. The films were characterized by x-ray diffraction that confirms that the films have good crystalline quality, single phase and c-axis orientation. The Atomic force microscopic (AFM) results show that surface roughness and average grain size increase with film thickness. The resistivity measurements show an insulator to metal transition that correlates well with the magnetic ordering temperature. X-ray photoemission spectroscopy measurements suggests that Te ions are in the Te 4+ state, while the Mn ions stay in the Mn 2+ and Mn 3+ valence states.

We have synthesized the Zn1-xCoxO (x=0.01, 0.02, 0.03 and 0.05) nanoparticles by the sol-gel method. The adopted sal gel method needs no reaction agent to control the formation of precipitation except ammonia that is used to control the pH. These samples are characterized using x-ray diffraction (XRD), Scanning Electron Microscope (SEM), Ultraviolet/Visible(UV/Vis) spectroscopy, Fluorescence spectroscopy, Raman spectroscopy and Fourier transform infra red (FTIR) spectroscopy. The x-ray diffraction patterns show that all the sample are formed in single phase with a complete solubility of Co ions in the ZnO matrix. SEM micrographs show that the Co doped ZnO nanoparticles are hexagonal with wurtzite structure. We have found slight agglomeration of naoparticles for higher concentration of cobalt Energy dispersive x-ray spectroscopy (EDS) confirms the presence of Zn, Co and 0 elements. The particle sizes range between 50 and 60 nm. We have observed a decrease in fluorescence intensity with the increase in Co doping but all the Co doped samples show higher value of intensity as compared to pure ZnO in the visible range of spectrum. Raman spectroscopy reveals that the characteristic intense band of ZnO at 435 cm(-1) exhibits a decrease in intensity and slightly red shifts with the Co doping. The overall intensity of the samples shows a decrease with the increase in Co doping. FTiR spectra exhibit that the Zn-O band at similar to 497 cm(-1) for pure ZnO is shifted to lower frequency with the increase in Co doping. (C) 2014 Elsevier B.V. All rights reserved.

Graphical abstract: Resistivity versus temperature plots of La{sub 0.85}Te{sub 0.15}MnO{sub 3} thin film under the applied magnetic field of 0 T, 5 T and 8 T. - Highlights: • La{sub 0.85}Te{sub 0.15}MnO{sub 3} manganite thin film is deposited on LaAlO{sub 3} using PLD technique. • Film is deposited at 750 °C, and is highly crystalline, single phase and c-axis oriented. • The film consists of grains with an average diameter of 60 nm. • Resistivity plots display double insulator-metal transitions. • XPS results confirm the electron doped (n-type) nature of the film. - Abstract: We report the structural, electronic transport and X-ray photoemission spectroscopic study of 100 nm thin film of La{sub 0.85}Te{sub 0.15}MnO{sub 3} grown on (0 0 1) LaAlO{sub 3} single crystal substrate by pulsed laser deposition. XRD results confirm that the film has good crystalline quality, single phase, and has a c-axis orientation. The atomic force microscopic (AFM) results showed that the film consists of grains with an average diameter of 60 nm. The resistivity measurement showed double insulator-metal transitions in absence and as well as in presence of the magnetic field. The resistivity peaks are ascribed to the intrinsic contribution of LTMO film and the tunnellingmore » of spin-polarized electrons at grain boundaries. X-ray photoemission spectroscopy measurements suggest that Te ions are in the Te{sup 4+} state, while the Mn ions are forced to stay in the Mn{sup 2+} and Mn{sup 3+} valence state.« less

A convenient synthesis of a new series of nano steroidal pyrazolones is reported. They were characterized by X-ray diffraction, scanning electron microscopy, UV–vis light, Fourier transform-infrared spectroscopy, 1 H and 13 C nuclear magnetic resonance, mass spectroscopy and analytical data. The X-ray diffraction patterns at room temperature showed that two nano steroids, 7 and 8 , are formed in single phase with hexagonal crystal symmetry, while nano steroid 9 is formed with orthorhombic crystal symmetry. Compounds 1 – 3 are formed with hexagonal, monoclinic and tetragonal crystal symmetry, respectively. Scanning electron microscopy showed that the crystals of nano steroids 7 – 9 are brick-shaped agglomerates with less sharp edges and a rough surface with a few microcrystals, while the homogeneous crystal of nano steroid 3 has an approximate spherical morphology of nano particles conjoined to the chains. UV–vis absorption analysis showed that the band gap energy of nano steroids 7 and 8 was 3.70 eV and 4.61 eV, while that of 2 and 3 was 4.38 eV and 4.27 eV, respectively. Nano steroids 2 , 3 and 7 – 9 were screened for antimicrobial activity against various strains; nano compound 7 showed potential antimicrobial activity.

We have studied the structural and dielectric properties of nano-crystalline LaFe1−xZnxO3 (0 ≤ x ≤ 0.3) pervoskite samples synthesized through sol–gel auto-combustion technique. X-ray diffraction and FTIR spectroscopy are used to confirm the single phase characteristics. Microstructural features are investigated using scanning electron microscope and compositional analysis is performed through energy dispersive spectroscopy. The average grain sizes, calculated from the Scherrer formula, lie in the range below 30 nm. The hysteresis (M-H) curves display a weak magnetic order and a shift in the hysteresis loops. Dielectric response has been discussed, in the framework of “universal dielectric response” model. The value of dielectric constant (ɛ′) increases drastically on Zn doping. The dielectric loss factor (ɛ″) shows Debye like dipolar relaxation behavior. The observed peaks in loss factor (ɛ″) are attributed to the fact that a strong correlation between the conduction mechanism and the dielectric behavior exists in ferrites.

In this study, we have investigated the structure, temperature-dependent resistivity, magnetization, and dielectric properties of La1−x Te x MnO3±δ (x = 0.10 and 0.15). X-ray diffraction analysis confirms the rhombohedral crystal symmetry with space group R $$ \overline{3} $$ c. For both the samples, the temperature dependence of magnetization plots show paramagnetic-to-ferromagnetic phase transition. The Curie temperature (T c) and magnitude of magnetization increase with the Te concentration. Field-dependent magnetization produces the asymmetric hysteresis loop that has been attributed to the magneto crystalline anisotropy induced by lattice distortion and the rare earth spin coupling at room temperature. Temperature-dependent resistivity plots exhibit metal–insulator transition (MIT) and charge-ordering state. These plots have been fitted using variable range hopping model, and the density of states [N(EF)] has been estimated. Magnetoresistance is measured as a function of temperature in the field of 1T, 5T, and 8T. The dielectric constant shows an anomaly near MIT. The dielectric constant exhibits a peaking behavior with the applied frequency and the temperature dependence of dielectric constant attains colossal values at high temperatures.

We report the structural, morphological and magneto-transport properties of electron doped La0.85Te0.15MnO3 (LTMO) thin film grown on (001) LaAlO3 single crystal substrate by pulsed laser deposition (PLD). X-ray diffraction (XRD) results confirm that the film has good crystalline quality, single phase, and c-axis orientation. The atomic force microscopy (AFM) results have revealed that the film consists of grains with the average size in a range of 20–30 nm and root-mean square (rms) roughness of 0.27nm. The resistivity versus temperature measurement exhibits an insulator to metal transition (MIT). We have noticed a huge value of magnetoresistance (∼93%) close to MIT in presence of 8T field. X-ray photoemission spectroscopy confirms the electron doping and suggests that Te ions could be in the Te4+ state, while the Mn ions stay in the Mn2+ and Mn3+ valence state.

Synthesis of new bimetallic water-soluble complexes [C12H23N4O7CoCu]5H2O · Cl2(2), [C12H23N4O7CoNi]5H2O · Cl2(3) and [C12H23N4O7CoMn]5H2O · Cl2(4) has been achieved by reaction of the CoIII complex [C12H21N4O6Co]5H2O (1), with transition metal ions. Various physico-chemical techniques: elemental analysis, i.r., u.v.–vis., e.p.r,1H-, 13C- and 2D-n.m.r, spectroscopy, electrochemistry and molar conductance measurements were employed to characterize the complexes. The interaction of the monometallic complex (1) and bimetallic complexes (2–4) with calf thymus DNA have been carried out by u.v.–vis. titration, cyclic voltammetry (c.v.) and viscosity measurements. The intrinsic binding constant Kb of the complexes has been calculated. The absorption spectra of complexes exhibit a red shift with an overall ‘hyperchromic effect’ in the presence of CT-DNA. The binding affinity of the bimetallic complexes to calf thymus DNA is twofold in comparison with complex (1). The intrinsic binding constant value Kb of complex (1) was found to be 1.2 × 103 M−1, while the Kbvalue of complexes (2–4) were of the order of 1.4 × 103, 2.2 × 103 and 2.1 × 103 M−1, respectively. The Kb values are close to the border between classical and non-classical intercalation that indicates that the binding mode may be electrostatic, probably with covalent preference in bimetallic complexes. The electrochemical behavior of complexes (1–4) was studied in H2O and displays quasireversible CoII/CoI, CuII/CuI, NiII/NiI and MnII/MnIredox couples. The voltammetric studies of the complexes in the absence and in the presence of DNA exhibit a shift in the formal potential E0 and ratio of cathodic to anodic peak currents ipa/ipc, indicating binding of the complexes to calf thymus DNA. The viscosity of DNA decreases with increasing concentration of the complex, suggesting that complexes (2–4) bind to calf thymus DNA by electrostatic association with covalent preference.

We have studied the structural and dielectric properties of nano-crystalline LaFe1−xZnxO3(0≤x≤0.3) perovskite samples. The samples were synthesized by sol-gel auto-combustion technique and show the orthorhombic crystal structure at room temperature. Dielectric responses of studied system have been analyzed in the light of "universal dielectric response (UDR)"h model. The value of dielectric constant (e′) is found to be hugely enhanced with Zn substitution. To verify the UDR behaviour, the log(ν) versus log(νe′) graphs have been plotted. We have found the best linear fit for the host (LaFeO3) sample in the whole frequency range and for the other samples the linear behaviour is observed at low frequency regions only.