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12 results on '"Irie, Akemi"'

2. Multiplex Real-Time PCR-Based Newborn Screening for Severe Primary Immunodeficiency and Spinal Muscular Atrophy in Osaka, Japan: Our Results after 3 Years

Author

Kimizu, Tomokazu, primary, Nozaki, Masatoshi, additional, Okada, Yousuke, additional, Sawada, Akihisa, additional, Morisaki, Misaki, additional, Fujita, Hiroshi, additional, Irie, Akemi, additional, Matsuda, Keiko, additional, Hasegawa, Yuiko, additional, Nishi, Eriko, additional, Okamoto, Nobuhiko, additional, Kawai, Masanobu, additional, Imai, Kohsuke, additional, Suzuki, Yasuhiro, additional, Wada, Kazuko, additional, Mitsuda, Nobuaki, additional, and Ida, Shinobu, additional

Published
2024
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3. Newborn screening for spinal muscular atrophy in Osaka -challenges in a Japanese pilot study-

Author

Kimizu, Tomokazu, primary, Ida, Shinobu, additional, Oki, Keisuke, additional, Shima, Morimasa, additional, Nishimoto, Shizuka, additional, Nakajima, Ken, additional, Ikeda, Tae, additional, Mogami, Yukiko, additional, Yanagihara, Keiko, additional, Matsuda, Keiko, additional, Nishi, Eriko, additional, Hasegawa, Yuiko, additional, Nozaki, Masatoshi, additional, Fujita, Hiroshi, additional, Irie, Akemi, additional, Katayama, Toru, additional, Okamoto, Nobuhiko, additional, Imai, Kohsuke, additional, Nishio, Hisahide, additional, and Suzuki, Yasuhiro, additional

Published
2023
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11. Comparative evaluation of 99mTc-MIBI and 99m Tc-HMDP scintimammography for the diagnosis of breast cancer and its axillary metastases.

Author

Nishiyama, Yoshihiro, Yamamoto, Yuka, Ono, Yuko, Irie, Akemi, Yamauchi, Akira, Satoh, Katashi, and Ohkawa, Motoomi

Subjects
MAMMOGRAMS, BREAST cancer, RADIOPHARMACEUTICALS, TISSUES, TUMORS
Abstract

Abstract. The purpose of the present study was to compare scintimammography using technetium-99m hexakis 2-methoxyisobutylisonitrile (MIBI) with that using [sup 99m]Tc-hydroxymethylene diphosphonate (HMDP) in the detection of breast cancer and its axillary lesions. The study population comprised 50 consecutive females with breast cancer who were scheduled for surgery. All patients underwent scintimammography with [sup 99m]Tc-MIBI and [sup 99m]Tc-HMDP. The images were acquired 5 min (early) and 2 h (delayed) after injection of each radiopharmaceutical. Regions of interest were placed over the breast tumour (T), the axillary lesion (A) and the normal ipsilateral breast tissue (N). The two count ratios were calculated, i.e. the tumour to normal breast tissue ratio (T/N) and the axillary lymph node to normal breast tissue ratio (A/N). For the breast tumours, using [sup 99m]Tc-MIBI the positive rate was 86% (43/50) for the early and 72% (36/50) for the delayed images. The corresponding values using [sup 99m]Tc-HMDP were 72% (36/50) and 40% (20/50), respectively. Histopathological examination revealed metastatic lymph node involvement in 22 patients. For the axillary lesions, using [sup 99m]Tc-MIBI the positive rate was 72.7% (16/22) for the early and 54.5% (12/22) for the delayed images. Using [sup 99m]Tc-HMDP, the positive rate was only 18.2% (4/22) for the early and 4.5% (1/22) for the delayed images. Using [sup 99m]Tc-MIBI, the mean T/N (+/-SD) ratios on early and delayed images were 2.69+/-1.64 and 2.03+/-1.16, respectively, and the mean A/N... [ABSTRACT FROM AUTHOR]

Published
2001
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