218 results on '"Iovanna, J. L."'
Search Results
2. Adénocarcinome résécable de la tête du pancréas : la résection R0 est-elle une illusion ?
- Author
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Turrini, O., Gilabert, M., Ewald, J., Moutardier, V., Delpero, J.-R., and Iovanna, J.-L.
- Published
- 2017
- Full Text
- View/download PDF
3. Cellular Stress in Acute Pancreatitis
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Iovanna, J. L., Iovanna, Juan, editor, and Ismailov, Uktam, editor
- Published
- 2009
- Full Text
- View/download PDF
4. Consequences of DJ-1 upregulation following p53 loss and cell transformation
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Vasseur, S, Afzal, S, Tomasini, R, Guillaumond, F, Tardivel-Lacombe, J, Mak, T W, and Iovanna, J L
- Published
- 2012
- Full Text
- View/download PDF
5. TP53INP1 decreases pancreatic cancer cell migration by regulating SPARC expression
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Seux, M, Peuget, S, Montero, M P, Siret, C, Rigot, V, Clerc, P, Gigoux, V, Pellegrino, E, Pouyet, L, N'Guessan, P, Garcia, S, Dufresne, M, Iovanna, J L, Carrier, A, André, F, and Dusetti, N J
- Published
- 2011
- Full Text
- View/download PDF
6. VAV2 regulates epidermal growth factor receptor endocytosis and degradation
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Thalappilly, S, Soubeyran, P, Iovanna, J L, and Dusetti, N J
- Published
- 2010
- Full Text
- View/download PDF
7. Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E
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Andrieu, C, Taieb, D, Baylot, V, Ettinger, S, Soubeyran, P, De-Thonel, A, Nelson, C, Garrido, C, So, A, Fazli, L, Bladou, F, Gleave, M, Iovanna, J L, and Rocchi, P
- Published
- 2010
- Full Text
- View/download PDF
8. Tumor Protein p53-Induced Nuclear Protein (TP53INP1) Expression in Medullary Thyroid Carcinoma: A Molecular Guide to the Optimal Extent of Surgery?
- Author
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Taïeb, D., Giusiano, S., Sebag, F., Marcy, M., de Micco, C., Palazzo, F. F., Dusetti, N. J., Iovanna, J. L., Henry, J. F., Garcia, S., and Taranger-Charpin, Colette
- Published
- 2010
- Full Text
- View/download PDF
9. Combined inhibition of PAK7, MAP3K7 and CK2α kinases inhibits the growth of MiaPaCa2 pancreatic cancer cell xenografts
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Giroux, V, Iovanna, J L, Garcia, S, and Dagorn, J-C
- Published
- 2009
- Full Text
- View/download PDF
10. PAP1 signaling involves MAPK signal transduction
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Ferrés-Masó, M., Sacilotto, N., López-Rodas, G., Dagorn, J. C., Iovanna, J. L., Closa, D., and Folch-Puy, E.
- Published
- 2009
- Full Text
- View/download PDF
11. New strategies and designs in pancreatic cancer research: consensus guidelines report from a European expert panel†
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Van Laethem, J.-L., Verslype, C., Iovanna, J. L., Michl, P., Conroy, T., Louvet, C., Hammel, P., Mitry, E., Ducreux, M., Maraculla, T., Uhl, W., Van Tienhoven, G., Bachet, J. B., Maréchal, R., Hendlisz, A., Bali, M., Demetter, P., Ulrich, F., Aust, D., Luttges, J., Peeters, M., Mauer, M., Roth, A., Neoptolemos, J. P., and Lutz, M.
- Published
- 2012
- Full Text
- View/download PDF
12. Acute-phase reaction of the pancreas
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Iovanna, J. L., primary, Archange, C., additional, and Nowak, J., additional
- Published
- 2008
- Full Text
- View/download PDF
13. Could calcium/calmodulin-dependent kinase IV be a therapeutic target for Type 2 diabetes?: A15 (P33)
- Author
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Muller, D S, King, A J, Liu, B, Richardson, C, Malicet, C, Iovanna, J L, Jones, P M, and Persaud, S J
- Published
- 2009
14. Glucose reciprocally alters p8 and irs2 expression via calcium/calmodulin-dependent kinase IV to regulate beta-cell mass: A33
- Author
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Muller, D S, King, A, Liu, B, Bowe, J, Malicet, C, Richardson, C, March, P, Iovanna, J L, Jones, P M, and Persaud, S J
- Published
- 2008
15. Anti-inflammatory effects of pancreatitis associated protein in inflammatory bowel disease
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Gironella, M, Iovanna, J L, Sans, M, Gil, F, Peñalva, M, Closa, D, Miquel, R, Piqué, J M, and Panés, J
- Published
- 2005
16. Expression of HIP/PAP mRNA in Human Hepatoma Cell Lines
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CERVELLO, M., GIANNITRAPANI, L., LA ROSA, M., NOTARBARTOLO, M., D'ALESSANDRO, N., VIRRUSO, L., IOVANNA, J. L., and MONTALTO, G.
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- 2002
17. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
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Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Arozena, A. A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., Adhihetty, P. J., Adler, S. G., Agam, G., Agarwal, R., Aghi, M. K., Agnello, M., Agostinis, P., Aguilar, P. V., Aguirre-Ghiso, J., Airoldi, E. M., Ait-Si-Ali, S., Akematsu, T., Akporiaye, E. T., Al-Rubeai, M., Albaiceta, G. M., Albanese, C., Albani, D., Albert, M. L., Aldudo, J., Algül, H., Alirezaei, M., Alloza, I., Almasan, A., Almonte-Beceril, M., Alnemri, E. S., Alonso, C., Altan-Bonnet, N., Altieri, D. C., Alvarez, S., Alvarez-Erviti, L., Alves, S., Amadoro, G., Amano, A., Amantini, C., Ambrosio, S., Amelio, I., Amer, A. O., Amessou, M., Amon, A., An, Z., Anania, F. A., Andersen, S. U., Andley, U. P., Andreadi, C. K., Andrieu-Abadie, N., Anel, A., Ann, D. K., Anoopkumar-Dukie, S., Antonioli, M., Aoki, H., Apostolova, N., Aquila, S., Aquilano, K., Araki, K., Arama, E., Aranda, A., Araya, J., Arcaro, A., Arias, E., Arimoto, H., Ariosa, A. R., Armstrong, J. L., Arnould, T., Arsov, I., Asanuma, K., Askanas, V., Asselin, E., Atarashi, R., Atherton, S. S., Atkin, J. D., Attardi, L. D., Auberger, P., Auburger, G., Aurelian, L., Autelli, R., Avagliano, L., Avantaggiati, M. L., Avrahami, L., Azad, N., Awale, S., Bachetti, T., Backer, J. M., Bae, D. -H., Bae, J. -S., Bae, O. -N., Bae, S. H., Baehrecke, E. H., Baek, S. -H., Baghdiguian, S., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X. -Y., Bailly, Y., Balaji, K. N., Balduini, W., Ballabio, A., Balzan, R., Banerjee, R., Bánhegyi, G., Bao, H., Barbeau, B., Barrachina, M. D., Barreiro, E., Bartel, B., Bartolomé, A., Bassham, D. C., Bassi, M. T., Bast, R. C., J, R., Basu, A., Batista, M. T., Batoko, H., Battino, M., Bauckman, K., Baumgarner, B. L., Bayer, K. U., Beale, R., Beaulieu, J. -F., Beck, G. R., Becker, C., Beckham, J. D., Bédard, P. -A., Bednarski, P. J., Begley, T. J., Behl, C., Behrends, C., Behrens, G. M. N., Behrns, K. E., Bejarano, E., Belaid, A., Belleudi, F., Bénard, G., Berchem, G., Bergamaschi, D., Bergami, M., Berkhout, B., Berliocchi, L., Bernard, A., Bernard, M., Bernassola, F., Bertolotti, A., Bess, A. S., Besteiro, S., Bettuzzi, S., Bhalla, S., Bhattacharyya, S., Bhutia, S. K., Biagosch, C., Bianchi, M. W., Biard-Piechaczyk, M., Billes, V., Bincoletto, C., Bingol, B., Bird, S. W., Bitoun, M., Bjedov, I., Blackstone, C., Blanc, L., Blanco, G. A., Blomhoff, H. K., Boada-Romero, E., Böckler, S., Boes, M., Boesze-Battaglia, K., Boise, L. H., Bolino, A., Boman, A., Bonaldo, P., Bordi, M., Bosch, J., Botana, L. M., Botti, J., Bou, G., Bouché, M., Bouchecareilh, M., Boucher, M. -J., Boulton, M. E., Bouret, S. G., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N., Braga, V. M. M., Brancolini, C., Braus, G. H., Bravo-San-Pedro, J. M., Brennan, L. A., Bresnick, E. H., Brest, P., Bridges, D., Bringer, M. -A., Brini, M., Brito, G. C., Brodin, B., Brookes, P. S., Brown, E. J., Brown, K., Broxmeyer, H. E., Bruhat, A., Brum, P. C., Brumell, J. H., Brunetti-Pierri, N., Bryson-Richardson, R. J., Buch, S., Buchan, A. M., Budak, H., Bulavin, D. V., Bultman, S. J., Bultynck, G., Bumbasirevic, V., Burelle, Y., Burke, R. E., Burmeister, M., Bütikofer, P., Caberlotto, L., Cadwell, K., Cahova, M., Cai, D., Cai, J., Cai, Q., Calatayud, S., Camougrand, N., Campanella, M., Campbell, G. R., Campbell, M., Campello, S., Candau, R., Caniggia, I., Cantoni, L., Cao, L., Caplan, A. B., Caraglia, M., Cardinali, C., Cardoso, S. M., Carew, J. S., Carleton, L. A., Carlin, C. R., Carloni, S., Carlsson, S. R., Carmona-Gutierrez, D., Carneiro, L. A. M., Carnevali, O., Carra, S., Carrier, A., Carroll, B., Casas, C., Casas, J., Cassinelli, G., Castets, P., Castro-Obregon, S., Cavallini, G., Ceccherini, I., Cecconi, F., Cederbaum, A. I., Ceña, V., Cenci, S., Cerella, C., Cervia, D., Cetrullo, S., Chaachouay, H., Chae, H. -J., Chagin, A. S., Chai, C. -Y., Chakrabarti, G., Chamilos, G., Chan, E. Y. W., Chan, M. T. V., Chandra, D., Chandra, P., Chang, C. -P., Chang, R. C. -C., Chang, T. Y., Chatham, J. C., Chatterjee, S., Chauhan, S., Che, Y., Cheetham, M. E., Cheluvappa, R., Chen, C. -J., Chen, G., Chen, G. -C., Chen, H., Chen, J. W., Chen, J. -K., Chen, M., Chen, P., Chen, Q., Chen, S. -D., Chen, S., Chen, S. S. -L., Chen, W., Chen, W. -J., Chen, W. Q., Chen, X., Chen, Y. -H., Chen, Y. -G., Chen, Y., Chen, Y. -J., Chen, Y. -Q., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, H., Cheong, H., Cherry, S., Chesney, J., Cheung, C. H. A., Chevet, E., Chi, H. C., Chi, S. -G., Chiacchiera, F., Chiang, H. -L., Chiarelli, R., Chiariello, M., Chieppa, M., Chin, L. -S., Chiong, M., Chiu, G. N. C., Cho, D. -H., Cho, S. -G., Cho, W. C., Cho, Y. -Y., Cho, Y. -S., Choi, A. M. K., Choi, E. -J., Choi, E. -K., Choi, J., Choi, M. E., Choi, S. -I., Chou, T. -F., Chouaib, S., Choubey, D., Choubey, V., Chow, K. -C., Chowdhury, K., Chu, C. T., Chuang, T. -H., Chun, T., Chung, H., Chung, T., Chung, Y. -L., Chwae, Y. -J., Cianfanelli, V., Ciarcia, R., Ciechomska, I. A., Ciriolo, M. R., Cirone, M., Claerhout, S., Clague, M. J., Cl� ria, J., Clarke, P. G. H., Clarke, R., Clementi, E., Cleyrat, C., Cnop, M., Coccia, E. M., Cocco, T., Codogno, P., Coers, J., Cohen, E. E. W., Colecchia, D., Coletto, L., Coll, N. S., Colucci-Guyon, E., Comincini, S., Condello, M., Cook, K. L., Coombs, G. H., Cooper, C. D., Cooper, J. M., Coppens, I., Corasaniti, M. T., Corazzari, M., Corbalan, R., Corcelle-Termeau, E., Cordero, M. D., Corral-Ramos, C., Corti, O., Cossarizza, A., Costelli, P., Costes, S., Cotman, S. L., Coto-Montes, A., Cottet, S., Couve, E., Covey, L. R., Cowart, L. A., Cox, J. S., Coxon, F. P., Coyne, C. B., Cragg, M. S., Craven, R. J., Crepaldi, T., Crespo, J. L., Criollo, A., Crippa, V., Cruz, M. T., Cuervo, A. M., Cuezva, J. M., Cui, T., Cutillas, P. R., Czaja, M. J., Czyzyk-Krzeska, M. F., Dagda, R. K., Dahmen, U., Dai, C., Dai, W., Dai, Y., Dalby, K. N., Valle, L. D., Dalmasso, G., D'Amelio, M., Damme, M., Darfeuille-Michaud, A., Dargemont, C., Darley-Usmar, V. M., Dasarathy, S., Dasgupta, B., Dash, S., Dass, C. R., Davey, H. M., Davids, L. M., Dávila, D., Davis, R. J., Dawson, T. M., Dawson, V. L., Daza, P., de Belleroche, J., de Figueiredo, P., de Figueiredo, R. C. B. Q., de la Fuente, J., De Martino, L., De Matteis, A., De Meyer, G. R. Y., De Milito, A., De Santi, M., de Souza, W., De Tata, V., De Zio, D., Debnath, J., Dechant, R., Decuypere, J. -P., Deegan, S., Dehay, B., Del Bello, B., Del Re, D. P., Delage-Mourroux, R., Delbridge, L. M. D., Deldicque, L., Delorme-Axford, E., Deng, Y., Dengjel, J., Denizot, M., Dent, P., Der, C. J., Deretic, V., Derrien, B., Deutsch, E., Devarenne, T. P., Devenish, R. J., Di Bartolomeo, S., Di Daniele, N., Di Domenico, F., Di Nardo, A., Di Paola, S., Di Pietro, A., Di Renzo, L., Di Antonio, A., Díaz-Araya, G., Díaz-Laviada, I., Diaz-Meco, M. T., Diaz-Nido, J., Dickey, C. A., Dickson, R. C., Diederich, M., Digard, P., Dikic, I., Dinesh-Kumar, S. P., Ding, C., Ding, W. -X., Ding, Z., Dini, L., Distler, J. H. W., Diwan, A., Djavaheri-Mergny, M., Dmytruk, K., Dobson, R. C. J., Doetsch, V., Dokladny, K., Dokudovskaya, S., Donadelli, M., Dong, X. C., Dong, X., Dong, Z., Donohue, T. M., Donohue-Jr, T. M., Doran, K. S., D'Orazi, G., Dorn, G. W., Dosenko, V., Dridi, S., Drucker, L., Du, J., L. -L., Du, Du, L., du Toit, A., Dua, P., Duan, L., Duann, P., Dubey, V. K., Duchen, M. R., Duchosal, M. A., Duez, H., Dugail, I., Dumit, V. I., Duncan, M. C., Dunlop, E. A., Dunn, W. A., Dupont, N., Dupuis, L., Durán, R. V., Durcan, T. M., Duvezin-Caubet, S., Duvvuri, U., Eapen, V., Ebrahimi-Fakhari, D., Echard, A., Eckhart, L., Edelstein, C. L., Edinger, A. L., Eichinger, L., Eisenberg, T., Eisenberg-Lerner, A., Eissa, N. T., El-Deiry, W. S., El-Khoury, V., Elazar, Z., Eldar-Finkelman, H., Elliott, C. J. H., Emanuele, E., Emmenegger, U., Engedal, N., Engelbrecht, A. -M., Engelender, S., Enserink, J. M., Erdmann, R., Erenpreisa, J., Eri, R., Eriksen, J. L., Erman, A., Escalante, R., Eskelinen, E. -L., Espert, L., Esteban-Martínez, L., Evans, T. J., Fabri, M., Fabrias, G., Fabrizi, C., Facchiano, A., Færgeman, N. J., Faggioni, A., Fairlie, W. D., Fan, C., Fan, D., Fan, J., Fang, S., Fanto, M., Fanzani, A., Farkas, T., Faure, M., Favier, F. B., Fearnhead, H., Federici, M., Fei, E., Felizardo, T. C., Feng, H., Feng, Y., Ferguson, T. A., Fernández, Á. F., Fernandez-Barrena, M. G., Fernandez-Checa, J. C., Fernández-López, A., Fernandez-Zapico, M. E., Feron, O., Ferraro, E., Ferreira-Halder, C. V., Fesus, L., Feuer, R., Fiesel, F. C., Filippi-Chiela, E. C., Filomeni, G., Fimia, G. M., Fingert, J. H., Finkbeiner, S., Finkel, T., Fiorito, F., Fisher, P. B., Flajolet, M., Flamigni, F., Florey, O., Florio, S., Floto, R. A., Folini, M., Follo, C., Fon, E. A., Fornai, F., Fortunato, F., Fraldi, A., Franco, R., Francois, A., François, A., Frankel, L. B., Fraser, I. D. C., Frey, N., Freyssenet, D. G., Frezza, C., Friedman, S. L., Frigo, D. E., Fu, D., Fuentes, J. M., Fueyo, J., Fujitani, Y., Fujiwara, Y., Fujiya, M., Fukuda, M., Fulda, S., Fusco, C., Gabryel, B., Gaestel, M., Gailly, P., Gajewska, M., Galadari, S., Galili, G., Galindo, I., Galindo, M. F., Galliciotti, G., Galluzzi, L., Galy, V., Gammoh, N., Gandy, S., Ganesan, A. K., Ganesan, S., Ganley, I. G., Gannagé, M., Gao, F. -B., Gao, F., Gao, J. -X., Nannig, L. G., Véscovi, E. G., Garcia-Macía, M., Garcia-Ruiz, C., Garg, A. D., Garg, P. K., Gargini, R., Gassen, N. C., Gatica, D., Gatti, E., Gavard, J., Gavathiotis, E., Ge, L., Ge, P., Ge, S., Gean, P. -W., Gelmetti, V., Genazzani, A. A., Geng, J., Genschik, P., Gerner, L., Gestwicki, J. E., Gewirtz, D. A., Ghavami, S., Ghigo, E., Ghosh, D., Giammarioli, A. M., Giampieri, F., Giampietri, C., Giatromanolaki, A., Gibbings, D. J., Gibellini, L., Gibson, S. B., Ginet, V., Giordano, A., Giorgini, F., Giovannetti, E., Girardin, S. E., Gispert, S., Giuliano, S., Gladson, C. L., Glavic, A., Gleave, M., Godefroy, N., Gogal, R. M., Gokulan, K., Goldman, G. H., Goletti, D., Goligorsky, M. S., Gomes, A. V., Gomes, L. C., Gomez, H., Gomez-Manzano, C., Gómez-Sánchez, R., Gonçalves, D. A. P., Goncu, E., Gong, Q., Gongora, C., Gonzalez, C. B., Gonzalez-Alegre, P., Gonzalez-Cabo, P., González-Polo, R. A., Goping, I. S., Gorbea, C., Gorbunov, N. V., Goring, D. R., Gorman, A. M., Gorski, S. M., Goruppi, S., Goto-Yamada, S., Gotor, C., Gottlieb, R. A., Gozes, I., Gozuacik, D., Graba, Y., Graef, M., Granato, G. E., Grant, G. D., Grant, S., Gravina, G. L., Green, D. R., Greenhough, A., Greenwood, M. T., Grimaldi, B., Gros, F., Grose, C., Groulx, J. -F., Gruber, F., Grumati, P., Grune, T., Guan, J. -L., Guan, K. -L., Guerra, B., Guillen, C., Gulshan, K., Gunst, J., Guo, C., Guo, L., Guo, M., Guo, W., Guo, X. -G., Gust, A. A., Gustafsson, Å. B., Gutierrez, E., Gutierrez, M. G., Gwak, H. -S., Haas, A., Haber, J. E., Hadano, S., Hagedorn, M., Hahn, D. R., Halayko, A. J., Hamacher-Brady, A., Hamada, K., Hamai, A., Hamann, A., Hamasaki, M., Hamer, I., Hamid, Q., Hammond, E. M., Han, F., Han, W., Handa, J. T., Hanover, J. A., Hansen, M., Harada, M., Harhaji-Trajkovic, L., Harper, J. W., Harrath, A. H., Harris, A. L., Harris, J., Hasler, U., Hasselblatt, P., Hasui, K., Hawley, R. G., Hawley, T. S., He, C., C. Y., He, He, F., He, G., R. -R., He, X. -H., He, Y. -W., He, Y. -Y., He, Heath, J. K., Hébert, M. -J., Heinzen, R. A., Helgason, G. V., Hensel, M., Henske, E. P., Her, C., Herman, P. K., Hernández, A., Hernandez, C., Hernández-Tiedra, S., Hetz, C., Hiesinger, P. R., Higaki, K., Hilfiker, S., Hill, B. G., Hill, J. A., Hill, W. D., Hino, K., Hofius, D., Hofman, P., Höglinger, G. U., Höhfeld, J., Holz, M. K., Hong, Y., Hood, D. A., Hoozemans, J. J. M., Hoppe, T., Hsu, C., Hsu, C. -Y., Hsu, L. -C., Hu, D., Hu, G., H. -M., Hu, Hu, H., M. C., Hu, Y. -C., Hu, Z. -W., Hu, Hua, F., Hua, Y., Huang, C., Huang, H. -L., Huang, K. -H., Huang, K. -Y., Huang, S., Huang, W. -P., Huang, Y. -R., Huang, Y., Huber, T. B., Huebbe, P., Huh, W. -K., Hulmi, J. J., Hur, G. M., Hurley, J. H., Husak, Z., Hussain, S. N. A., Hussain, S., Hwang, J. J., Hwang, S., Hwang, T. I. S., Ichihara, A., Imai, Y., Imbriano, C., Inomata, M., Into, T., Iovane, V., Iovanna, J. L., Iozzo, R. V., N. Y., Ip, Irazoqui, J. E., Iribarren, P., Isaka, Y., Isakovic, A. J., Ischiropoulos, H., Isenberg, J. S., Ishaq, M., Ishida, H., Ishii, I., Ishmael, J. E., Isidoro, C., Isobe, K. -I., Isono, E., Issazadeh-Navikas, S., Itahana, K., Itakura, E., Ivanov, A. I., Iyer, A. K. V., Izquierdo, J. M., Izumi, Y., Izzo, V., Jäättelä, M., Jaber, N., Jackson, D. J., Jackson, W. T., Jacob, T. G., Jacques, T. S., Jagannath, C., Jain, A., Jana, N. R., Jang, B. K., Jani, A., Janji, B., Jannig, P. R., Jansson, P. J., Jean, S., Jendrach, M., Jeon, J. -H., Jessen, N., Jeung, E. -B., Jia, K., Jia, L., Jiang, H., Jiang, L., Jiang, T., Jiang, X., Jiang, Y., Jiménez, A., Jin, C., Jin, H., Jin, L., Jin, M., Jin, S., Jinwal, U. K., E. -K., Jo, Johansen, T., Johnson, D. E., Johnson, G. V. W., Johnson, J. D., Jonasch, E., Jones, C., Joosten, L. A. B., Jordan, J., Joseph, A. -M., Joseph, B., Joubert, A. M., Ju, D., Ju, J., Juan, H. -F., Juenemann, K., Juhász, G., Jung, H. S., Jung, J. U., Jung, Y. -K., Jungbluth, H., Justice, M. J., Jutten, B., Kaakoush, N. O., Kaarniranta, K., Kaasik, A., Kabuta, T., Kaeffer, B., Kågedal, K., Kahana, A., Kajimura, S., Kakhlon, O., Kalia, M., Kalvakolanu, D. V., Kamada, Y., Kambas, K., Kaminskyy, V. O., Kampinga, H. 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Robin, Higaki, Katsumi, Hilfiker, Sabine, Hill, Bradford G., Hill, Joseph A., Hill, William D., Hino, Keisuke, Hofius, Daniel, Hofman, Paul, Höglinger, Günter U., Höhfeld, Jörg, Holz, Marina K., Hong, Yonggeun, Hood, David A., Hoozemans, Jeroen J.M., Hoppe, Thorsten, Hsu, Chin, Hsu, Chin-Yuan, Hsu, Li-Chung, Hu, Dong, Hu, Guochang, Hu, Hong-Ming, Hu, Hongbo, Hu, Ming Chang, Hu, Yu-Chen, Hu, Zhuo-Wei, Hua, Fang, Hua, Ya, Huang, Canhua, Huang, Huey-Lan, Huang, Kuo-How, Huang, Kuo-Yang, Huang, Shile, Huang, Shiqian, Huang, Wei-Pang, Huang, Yi-Ran, Huang, Yong, Huang, Yunfei, Huber, Tobias B., Huebbe, Patricia, Huh, Won-Ki, Hulmi, Juha J., Hur, Gang Min, Hurley, James H., Husak, Zvenyslava, Hussain, Sabah N.A., Hussain, Salik, Hwang, Jung Jin, Hwang, Seungmin, Hwang, Thomas I.S., Ichihara, Atsuhiro, Imai, Yuzuru, Imbriano, Carol, Inomata, Megumi, Into, Takeshi, Iovane, Valentina, Iovanna, Juan L., Iozzo, Renato V., Ip, Nancy Y., Irazoqui, Javier E., Iribarren, Pablo, Isaka, Yoshitaka, Isakovic, Aleksandra J., Ischiropoulos, Harry, Isenberg, Jeffrey S., Ishaq, Mohammad, Ishida, Hiroyuki, Ishii, Isao, Ishmael, Jane E., Isidoro, Ciro, Isobe, Ken-Ichi, Isono, Erika, Issazadeh-Navikas, Shohreh, Itahana, Koji, Itakura, Eisuke, Ivanov, Andrei I., Iyer, Anand Krishnan V., Izquierdo, José M., Izumi, Yotaro, Izzo, Valentina, Jäättelä, Marja, Jaber, Nadia, Jackson, Daniel John, Jackson, William T., Jacob, Tony George, Jacques, Thomas S., Jagannath, Chinnaswamy, Jain, Ashish, Jana, Nihar Ranjan, Jang, Byoung Kuk, Jani, Alkesh, Janji, Bassam, Jannig, Paulo Roberto, Jansson, Patric J., Jean, Steve, Jendrach, Marina, Jeon, Ju-Hong, Jessen, Niel, Jeung, Eui-Bae, Jia, Kailiang, Jia, Lijun, Jiang, Hong, Jiang, Hongchi, Jiang, Liwen, Jiang, Teng, Jiang, Xiaoyan, Jiang, Xuejun, Jiang, Ying, Jiang, Yongjun, Jiménez, Alberto, Jin, Cheng, Jin, Hongchuan, Jin, Lei, Jin, Meiyan, Jin, Shengkan, Jinwal, Umesh Kumar, Jo, Eun-Kyeong, Johansen, Terje, Johnson, Daniel E., Johnson, Gail V.W., Johnson, James D., Jonasch, Eric, Jones, Chri, Joosten, Leo A.B., Jordan, Joaquin, Joseph, Anna-Maria, Joseph, Bertrand, Joubert, Annie M., Ju, Dianwen, Ju, Jingfang, Juan, Hsueh-Fen, Juenemann, Katrin, Juhász, Gábor, Jung, Hye Seung, Jung, Jae U., Jung, Yong-Keun, Jungbluth, Heinz, Justice, Matthew J., Jutten, Barry, Kaakoush, Nadeem O., Kaarniranta, Kai, Kaasik, Allen, Kabuta, Tomohiro, Kaeffer, Bertrand, Kågedal, Katarina, Kahana, Alon, Kajimura, Shingo, Kakhlon, Or, Kalia, Manjula, Kalvakolanu, Dhan V., Kamada, Yoshiaki, Kambas, Konstantino, Kaminskyy, Vitaliy O., Kampinga, Harm H., Kandouz, Mustapha, Kang, Chanhee, Kang, Rui, Kang, Tae-Cheon, Kanki, Tomotake, Kanneganti, Thirumala-Devi, Kanno, Haruo, Kanthasamy, Anumantha G., Kantorow, Marc, Kaparakis-Liaskos, Maria, Kapuy, Orsolya, Karantza, Vassiliki, Karim, Md Razaul, Karmakar, Parimal, Kaser, Arthur, Kaushik, Susmita, Kawula, Thoma, Kaynar, A. Murat, Ke, Po-Yuan, Ke, Zun-Ji, Kehrl, John H., Keller, Kate E., Kemper, Jongsook Kim, Kenworthy, Anne K., Kepp, Oliver, Kern, Andrea, Kesari, Santosh, Kessel, David, Ketteler, Robin, Kettelhut, Isis do Carmo, Khambu, Bilon, Khan, Muzamil Majid, Khandelwal, Vinoth K.M., Khare, Sangeeta, Kiang, Juliann G., Kiger, Amy A., Kihara, Akio, Kim, Arianna L., Kim, Cheol Hyeon, Kim, Deok Ryong, Kim, Do-Hyung, Kim, Eung Kweon, Kim, Hye Young, Kim, Hyung-Ryong, Kim, Jae-Sung, Kim, Jeong Hun, Kim, Jin Cheon, Kim, Jin Hyoung, Kim, Kwang Woon, Kim, Michael D., Kim, Moon-Moo, Kim, Peter K., Kim, Seong Who, Kim, Soo-Youl, Kim, Yong-Sun, Kim, Yonghyun, Kimchi, Adi, Kimmelman, Alec C., Kimura, Tomonori, King, Jason S., Kirkegaard, Karla, Kirkin, Vladimir, Kirshenbaum, Lorrie A., Kishi, Shuji, Kitajima, Yasuo, Kitamoto, Katsuhiko, Kitaoka, Yasushi, Kitazato, Kaio, Kley, Rudolf A., Klimecki, Walter T., Klinkenberg, Michael, Klucken, Jochen, Knævelsrud, Helene, Knecht, Erwin, Knuppertz, Laura, Ko, Jiunn-Liang, Kobayashi, Satoru, Koch, Jan C., Koechlin-Ramonatxo, Christelle, Koenig, Ulrich, Koh, Young Ho, Köhler, Katja, Kohlwein, Sepp D., Koike, Masato, Komatsu, Masaaki, Kominami, Eiki, Kong, Dexin, Kong, Hee Jeong, Konstantakou, Eumorphia G., Kopp, Benjamin T., Korcsmaros, Tama, Korhonen, Laura, Korolchuk, Viktor I., Koshkina, Nadya V., Kou, Yanjun, Koukourakis, Michael I., Koumenis, Constantino, Kovács, Attila L., Kovács, Tibor, Kovacs, Werner J., Koya, Daisuke, Kraft, Claudine, Krainc, Dimitri, Kramer, Helmut, Kravic-Stevovic, Tamara, Krek, Wilhelm, Kretz-Remy, Carole, Krick, Roswitha, Krishnamurthy, Malathi, Kriston-Vizi, Jano, Kroemer, Guido, Kruer, Michael C., Kruger, Rejko, Ktistakis, Nicholas T., Kuchitsu, Kazuyuki, Kuhn, Christian, Kumar, Addanki Pratap, Kumar, Anuj, Kumar, Ashok, Kumar, Deepak, Kumar, Dhiraj, Kumar, Rakesh, Kumar, Sharad, Kundu, Mondira, Kung, Hsing-Jien, Kuno, Atsushi, Kuo, Sheng-Han, Kuret, Jeff, Kurz, Tino, Kwok, Terry, Kwon, Taeg Kyu, Kwon, Yong Tae, Kyrmizi, Irene, La Spada, Albert R., Lafont, Frank, Lahm, Tim, Lakkaraju, Aparna, Lam, Truong, Lamark, Trond, Lancel, Steve, Landowski, Terry H., Lane, Darius J.R., Lane, Jon D., Lanzi, Cinzia, Lapaquette, Pierre, Lapierre, Louis R., Laporte, Jocelyn, Laukkarinen, Johanna, Laurie, Gordon W., Lavandero, Sergio, Lavie, Lena, Lavoie, Matthew J., Law, Betty Yuen Kwan, Law, Helen Ka-Wai, Law, Kelsey B., Layfield, Robert, Lazo, Pedro A., Le Cam, Laurent, Le Roch, Karine G., Le Stunff, Hervé, Leardkamolkarn, Vijittra, Lecuit, Marc, Lee, Byung-Hoon, Lee, Che-Hsin, Lee, Erinna F., Lee, Gyun Min, Lee, He-Jin, Lee, Hsinyu, Lee, Jae Keun, Lee, Jongdae, Lee, Ju-Hyun, Lee, Jun Hee, Lee, Michael, Lee, Myung-Shik, Lee, Patty J., Lee, Sam W., Lee, Seung-Jae, Lee, Shiow-Ju, Lee, Stella Y., Lee, Sug Hyung, Lee, Sung Sik, Lee, Sung-Joon, Lee, Sunhee, Lee, Ying-Ray, Lee, Yong J., Lee, Young H., Leeuwenburgh, Christiaan, Lefort, Sylvain, Legouis, Renaud, Lei, Jinzhi, Lei, Qun-Ying, Leib, David A., Leibowitz, Gil, Lekli, Istvan, Lemaire, Stéphane D., Lemasters, John J., Lemberg, Marius K., Lemoine, Antoinette, Leng, Shuilong, Lenz, Guido, Lenzi, Paola, Lerman, Lilach O., Barbato, Daniele Lettieri, Leu, Julia I. 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Sue, Menna-Barreto, Rubem F.S., Menon, Manoj B., Meraz-Ríos, Marco A., Merla, Giuseppe, Merlini, Luciano, Merlot, Angelica M., Meryk, Andrea, Meschini, Stefania, Meyer, Joel N., Mi, Man-Tian, Miao, Chao-Yu, Micale, Lucia, Michaeli, Simon, Michiels, Carine, Migliaccio, Anna Rita, Mihailidou, Anastasia Susie, Mijaljica, Dalibor, Mikoshiba, Katsuhiko, Milan, Enrico, Miller-Fleming, Leonor, Mills, Gordon B., Mills, Ian G., Minakaki, Georgia, Minassian, Berge A., Ming, Xiu-Fen, Minibayeva, Farida, Minina, Elena A., Mintern, Justine D., Minucci, Saverio, Miranda-Vizuete, Antonio, Mitchell, Claire H., Miyamoto, Shigeki, Miyazawa, Keisuke, Mizushima, Noboru, Mnich, Katarzyna, Mograbi, Baharia, Mohseni, Simin, Moita, Luis Ferreira, Molinari, Marco, Molinari, Maurizio, Møller, Andreas Buch, Mollereau, Bertrand, Mollinedo, Faustino, Mongillo, Marco, Monick, Martha M., Montagnaro, Serena, Montell, Craig, Moore, Darren J., Moore, Michael N., Mora-Rodriguez, Rodrigo, Moreira, Paula I., Morel, Etienne, Morelli, Maria Beatrice, Moreno, Sandra, Morgan, Michael J., Moris, Arnaud, Moriyasu, Yuji, Morrison, Janna L., Morrison, Lynda A., Morselli, Eugenia, Moscat, Jorge, Moseley, Pope L., Mostowy, Serge, Motori, Elisa, Mottet, Deni, Mottram, Jeremy C., Moussa, Charbel E.-H., Mpakou, Vassiliki E., Mukhtar, Hasan, Levy, Jean M. Mulcahy, Muller, Sylviane, Muñoz-Moreno, Raquel, Muñoz-Pinedo, Cristina, Münz, Christian, Murphy, Maureen E., Murray, James T., Murthy, Aditya, Mysorekar, Indira U., Nabi, Ivan R., Nabissi, Massimo, Nader, Gustavo A., Nagahara, Yukitoshi, Nagai, Yoshitaka, Nagata, Kazuhiro, Nagelkerke, Anika, Nagy, Péter, Naidu, Samisubbu R., Nair, Sreejayan, Nakano, Hiroyasu, Nakatogawa, Hitoshi, Nanjundan, Meera, Napolitano, Gennaro, Naqvi, Naweed I., Nardacci, Roberta, Narendra, Derek P., Narita, Masashi, Nascimbeni, Anna Chiara, Natarajan, Ramesh, Navegantes, Luiz C., Nawrocki, Steffan T., Nazarko, Taras Y., Nazarko, Volodymyr Y., Neill, Thoma, Neri, Luca M., Netea, Mihai G., Netea-Maier, Romana T., Neves, Bruno M., Ney, Paul A., Nezis, Ioannis P., Nguyen, Hang T.T., Nguyen, Huu Phuc, Nicot, Anne-Sophie, Nilsen, Hilde, Nilsson, Per, Nishimura, Mikio, Nishino, Ichizo, Niso-Santano, Mireia, Niu, Hua, Nixon, Ralph A., Njar, Vincent C.O., Noda, Takeshi, Noegel, Angelika A., Nolte, Elsie Magdalena, Norberg, Erik, Norga, Koenraad K., Noureini, Sakineh Kazemi, Notomi, Shoji, Notterpek, Lucia, Nowikovsky, Karin, Nukina, Nobuyuki, Nürnberger, Thorsten, O'donnell, Valerie B., O'donovan, Tracey, O'dwyer, Peter J., Oehme, Ina, Oeste, Clara L., Ogawa, Michinaga, Ogretmen, Besim, Ogura, Yuji, Oh, Young J., Ohmuraya, Masaki, Ohshima, Takayuki, Ojha, Rani, Okamoto, Koji, Okazaki, Toshiro, Oliver, F. Javier, Ollinger, Karin, Olsson, Stefan, Orban, Daniel P., Ordonez, Paulina, Orhon, Idil, Orosz, Laszlo, O'rourke, Eyleen J., Orozco, Helena, Ortega, Angel L., Ortona, Elena, Osellame, Laura D., Oshima, Junko, Oshima, Shigeru, Osiewacz, Heinz D., Otomo, Takanobu, Otsu, Kinya, Ou, Jing-Hsiung Jame, Outeiro, Tiago F., Ouyang, Dong-Yun, Ouyang, Hongjiao, Overholtzer, Michael, Ozbun, Michelle A., Ozdinler, P. Hande, Ozpolat, Bulent, Pacelli, Consiglia, Paganetti, Paolo, Page, Guyléne, Pages, Gille, Pagnini, Ugo, Pajak, Beata, Pak, Stephen C., Pakos-Zebrucka, Karolina, Pakpour, Nazzy, Palková, Zdena, Palladino, Francesca, Pallauf, Kathrin, Pallet, Nicola, Palmieri, Marta, Paludan, Søren R., Palumbo, Camilla, Palumbo, Silvia, Pampliega, Olatz, Pan, Hongming, Pan, Wei, Panaretakis, Theochari, Pandey, Aseem, Pantazopoulou, Areti, Papackova, Zuzana, Papademetrio, Daniela L., Papassideri, Issidora, Papini, Alessio, Parajuli, Nirmala, Pardo, Julian, Parekh, Vrajesh V., Parenti, Giancarlo, Park, Jong-In, Park, Junsoo, Park, Ohkmae K., Parker, Roy, Parlato, Rosanna, Parys, Jan B., Parzych, Katherine R., Pasquet, Jean-Max, Pasquier, Benoit, Pasumarthi, Kishore B.S., Patschan, Daniel, Pattingre, Sophie, Pattison, Scott, Pause, Arnim, Pavenstädt, Hermann, Pavone, Flaminia, Pedrozo, Zully, Peña, Fernando J., Peñalva, Miguel A., Pende, Mario, Peng, Jianxin, Penna, Fabio, Penninger, Josef M., Pensalfini, Anna, Pepe, Salvatore, Pereira, Gustavo J.S., Pereira, Paulo C., de la Cruz, Verónica Pérez, Pérez-Pérez, María Esther, Pérez-Rodríguez, Diego, Pérez-Sala, Dolore, Perier, Celine, Perl, Andra, Perlmutter, David H., Perrotta, Ida, Pervaiz, Shazib, Pesonen, Maija, Pessin, Jeffrey E., Peters, Godefridus J., Petersen, Morten, Petrache, Irina, Petrof, Basil J., Petrovski, Goran, Phang, James M., Piacentini, Mauro, Pierdominici, Marina, Pierre, Philippe, Pierrefite-Carle, Valérie, Pietrocola, Federico, Pimentel-Muiños, Felipe X., Pinar, Mario, Pineda, Benjamin, Pinkas-Kramarski, Ronit, Pinti, Marcello, Pinton, Paolo, Piperdi, Bilal, Piret, James M., Platanias, Leonidas C., Platta, Harald W., Plowey, Edward D., Pöggeler, Stefanie, Poirot, Marc, Polčic, Peter, Poletti, Angelo, Poon, Audrey H., Popelka, Hana, Popova, Blagovesta, Poprawa, Izabela, Poulose, Shibu M., Poulton, Joanna, Powers, Scott K., Powers, Ted, Pozuelo-Rubio, Mercede, Prak, Krisna, Prange, Reinhild, Prescott, Mark, Priault, Muriel, Prince, Sharon, Proia, Richard L., Proikas-Cezanne, Tassula, Prokisch, Holger, Promponas, Vasilis J., Przyklenk, Karin, Puertollano, Rosa, Pugazhenthi, Subbiah, Puglielli, Luigi, Pujol, Aurora, Puyal, Julien, Pyeon, Dohun, Qi, Xin, Qian, Wen-Bin, Qin, Zheng-Hong, Qiu, Yu, Qu, Ziwei, Quadrilatero, Joe, Quinn, Frederick, Raben, Nina, Rabinowich, Hannah, Radogna, Flavia, Ragusa, Michael J., Rahmani, Mohamed, Raina, Komal, Ramanadham, Sasanka, Ramesh, Rajagopal, Rami, Abdelhaq, Randall-Demllo, Sarron, Randow, Felix, Rao, Hai, Rao, V. 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Paul, Taylor, Mark J., Tchetina, Elena V., Tee, Andrew R., Teixeira-Clerc, Fatima, Telang, Sucheta, Tencomnao, Tewin, Teng, Ba-Bie, Teng, Ru-Jeng, Terro, Faraj, Tettamanti, Gianluca, Theiss, Arianne L., Theron, Anne E., Thomas, Kelly Jean, Thomé, Marcos P., Thomes, Paul G., Thorburn, Andrew, Thorner, Jeremy, Thum, Thoma, Thumm, Michael, Thurston, Teresa L.M., Tian, Ling, Till, Andrea, Ting, Jenny Pan-Yun, Ting, Jenny Pan Yun, Titorenko, Vladimir I., Toker, Lilach, Toldo, Stefano, Tooze, Sharon A., Topisirovic, Ivan, Torgersen, Maria Lyngaa, Torosantucci, Liliana, Torriglia, Alicia, Torrisi, Maria Rosaria, Tournier, Cathy, Towns, Roberto, Trajkovic, Vladimir, Travassos, Leonardo H., Triola, Gemma, Tripathi, Durga Nand, Trisciuoglio, Daniela, Troncoso, Rodrigo, Trougakos, Ioannis P., Truttmann, Anita C., Tsai, Kuen-Jer, Tschan, Mario P., Tseng, Yi-Hsin, Tsukuba, Takayuki, Tsung, Allan, Tsvetkov, Andrey S., Tu, Shuiping, Tuan, Hsing-Yu, Tucci, Marco, Tumbarello, David A., Turk, Bori, Turk, Vito, Turner, Robin F.B., Tveita, Anders A., Tyagi, Suresh C., Ubukata, Makoto, Uchiyama, Yasuo, Udelnow, Andrej, Ueno, Takashi, Umekawa, Midori, Umemiya-Shirafuji, Rika, Underwood, Benjamin R., Ungermann, Christian, Ureshino, Rodrigo P., Ushioda, Ryo, Uversky, Vladimir N., Uzcátegui, Néstor L., Vaccari, Thoma, Vaccaro, Maria I., Váchová, Libuše, Vakifahmetoglu-Norberg, Helin, Valdor, Rut, Valente, Enza Maria, Vallette, Francoi, Valverde, Angela M., Van den Berghe, Greet, Van Den Bosch, Ludo, van den Brink, Gijs R., van der Goot, F. 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- Subjects
Molecular Biology ,Cell Biology ,Settore BIO/06 - Anatomia Comparata E Citologia - Abstract
non presente
- Published
- 2016
18. Microwave promoted C-O coupling for synthesizing O-aryloxytriazole nucleoside analogues
- Author
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Cong, M., Xia, Y., Tang, J., Borge, L., Quéléver, G., Iovanna, J. L., Palma Rocchi, Ling Peng, Centre Interdisciplinaire de Nanoscience de Marseille (CINaM), and Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
[CHIM]Chemical Sciences ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2015
19. The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes KrasG12D-mediated pancreatic cancer initiation
- Author
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Loncle, C, primary, Molejon, M I, additional, Lac, S, additional, Tellechea, J I, additional, Lomberk, G, additional, Gramatica, L, additional, Fernandez Zapico, M F, additional, Dusetti, N, additional, Urrutia, R, additional, and Iovanna, J L, additional
- Published
- 2016
- Full Text
- View/download PDF
20. NUPR1, a new target in liver cancer: implication in controlling cell growth, migration, invasion and sorafenib resistance
- Author
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Emma, M R, primary, Iovanna, J L, additional, Bachvarov, D, additional, Puleio, R, additional, Loria, G R, additional, Augello, G, additional, Candido, S, additional, Libra, M, additional, Gulino, A, additional, Cancila, V, additional, McCubrey, J A, additional, Montalto, G, additional, and Cervello, M, additional
- Published
- 2016
- Full Text
- View/download PDF
21. TAp73 loss favors Smad-independent TGF-β signaling that drives EMT in pancreatic ductal adenocarcinoma
- Author
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Thakur, A K, primary, Nigri, J, additional, Lac, S, additional, Leca, J, additional, Bressy, C, additional, Berthezene, P, additional, Bartholin, L, additional, Chan, P, additional, Calvo, E, additional, Iovanna, J L, additional, Vasseur, S, additional, Guillaumond, F, additional, and Tomasini, R, additional
- Published
- 2016
- Full Text
- View/download PDF
22. Stromal SLIT2 impacts on pancreatic cancer-associated neural remodeling
- Author
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Secq, V, primary, Leca, J, additional, Bressy, C, additional, Guillaumond, F, additional, Skrobuk, P, additional, Nigri, J, additional, Lac, S, additional, Lavaut, M-N, additional, Bui, T-t, additional, Thakur, A K, additional, Callizot, N, additional, Steinschneider, R, additional, Berthezene, P, additional, Dusetti, N, additional, Ouaissi, M, additional, Moutardier, V, additional, Calvo, E, additional, Bousquet, C, additional, Garcia, S, additional, Bidaut, G, additional, Vasseur, S, additional, Iovanna, J L, additional, and Tomasini, R, additional
- Published
- 2015
- Full Text
- View/download PDF
23. Cu-mediated Selective N-arylation of Aminotriazole Acyclonucleosides
- Author
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Li, W., Fan, Y., Palma Rocchi, Zhu, R., Qu, F., Neyts, J., Iovanna, J. L., Ling Peng, Centre Interdisciplinaire de Nanoscience de Marseille (CINaM), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), and Cinam, Hal
- Published
- 2009
24. Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation
- Author
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Salazar, M, primary, Lorente, M, additional, García-Taboada, E, additional, Pérez Gómez, E, additional, Dávila, D, additional, Zúñiga-García, P, additional, María Flores, J, additional, Rodríguez, A, additional, Hegedus, Z, additional, Mosén-Ansorena, D, additional, Aransay, A M, additional, Hernández-Tiedra, S, additional, López-Valero, I, additional, Quintanilla, M, additional, Sánchez, C, additional, Iovanna, J L, additional, Dusetti, N, additional, Guzmán, M, additional, Francis, S E, additional, Carracedo, A, additional, Kiss-Toth, E, additional, and Velasco, G, additional
- Published
- 2014
- Full Text
- View/download PDF
25. Genetic inactivation of the pancreatitis-inducible gene Nupr1 impairs PanIN formation by modulating KrasG12D-induced senescence
- Author
-
Grasso, D, primary, Garcia, M N, additional, Hamidi, T, additional, Cano, C, additional, Calvo, E, additional, Lomberk, G, additional, Urrutia, R, additional, and Iovanna, J L, additional
- Published
- 2014
- Full Text
- View/download PDF
26. TAp73 is required for macrophage-mediated innate immunity and the resolution of inflammatory responses
- Author
-
Tomasini, R, primary, Secq, V, additional, Pouyet, L, additional, Thakur, A K, additional, Wilhelm, M, additional, Nigri, J, additional, Vasseur, S, additional, Berthezene, P, additional, Calvo, E, additional, Melino, G, additional, Mak, T W, additional, and Iovanna, J L, additional
- Published
- 2012
- Full Text
- View/download PDF
27. TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death
- Author
-
Seillier, M, primary, Peuget, S, additional, Gayet, O, additional, Gauthier, C, additional, N'Guessan, P, additional, Monte, M, additional, Carrier, A, additional, Iovanna, J L, additional, and Dusetti, N J, additional
- Published
- 2012
- Full Text
- View/download PDF
28. Consequences of DJ-1 upregulation following p53 loss and cell transformation
- Author
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Vasseur, S, primary, Afzal, S, additional, Tomasini, R, additional, Guillaumond, F, additional, Tardivel-Lacombe, J, additional, Mak, T W, additional, and Iovanna, J L, additional
- Published
- 2011
- Full Text
- View/download PDF
29. Expression TP53INP1 (Tumor Protein p53-Induced Nuclear Protein) dans le Carcinome Médullaire Thyroidien (CMT) : un guide moléculaire pour la chirurgie optimale ? (35)
- Author
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Sebag, F., primary, Taieb, D., additional, Marcy, M., additional, De Micco, C., additional, Iovanna, J.-L., additional, Garcia, S., additional, and Henry, J.-F., additional
- Published
- 2010
- Full Text
- View/download PDF
30. AUTOPHAGY PREVENTS CAERULEIN-INDUCED ACINAR CELL DEATH
- Author
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Grasso, D., primary, Ropolo, A., additional, Sacchetti, M. L., additional, Lo Re, A., additional, Pardo, R., additional, Iovanna, J. L., additional, and Vaccaro, M. I., additional
- Published
- 2008
- Full Text
- View/download PDF
31. Experimental acute pancreatitis in PAP/HIP knock-out mice
- Author
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Gironella, M., primary, Folch-Puy, E., additional, LeGoffic, A., additional, Garcia, S., additional, Christa, L., additional, Smith, A., additional, Tebar, L., additional, Hunt, S. P, additional, Bayne, R., additional, Smith, A. J H, additional, Dagorn, J.-C., additional, Closa, D., additional, and Iovanna, J. L, additional
- Published
- 2007
- Full Text
- View/download PDF
32. Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation.
- Author
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Salazar, M, Lorente, M, García-Taboada, E, Pérez Gómez, E, Dávila, D, Zúñiga-García, P, María Flores, J, Rodríguez, A, Hegedus, Z, Mosén-Ansorena, D, Aransay, A M, Hernández-Tiedra, S, López-Valero, I, Quintanilla, M, Sánchez, C, Iovanna, J L, Dusetti, N, Guzmán, M, Francis, S E, and Carracedo, A
- Subjects
KINASE inhibitors ,KINASE genetics ,KINASE regulation ,NEOPLASTIC cell transformation ,GENETIC transcription regulation - Abstract
Tribbles pseudokinase-3 (TRIB3) has been proposed to act as an inhibitor of AKT although the precise molecular basis of this activity and whether the loss of TRIB3 contributes to cancer initiation and progression remain to be clarified. In this study, by using a wide array of in vitro and in vivo approaches, including a Trib3 knockout mouse, we demonstrate that TRIB3 has a tumor-suppressing role. We also find that the mechanism by which TRIB3 loss enhances tumorigenesis relies on the dysregulation of the phosphorylation of AKT by the mTORC2 complex, which leads to an enhanced phosphorylation of AKT on Ser473 and the subsequent hyperphosphorylation and inactivation of the transcription factor FOXO3. These observations support the notion that loss of TRIB3 is associated with a more aggressive phenotype in various types of tumors by enhancing the activity of the mTORC2/AKT/FOXO axis. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
33. THE EXPRESSION OF THE VACUOLE MEMBRANE PROTEIN 1 (VMP1) IS NECESSARY AND SUFFICIENT TO TRIGGER AUTOPHAGY IN PANCREATIC CELLS
- Author
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Vaccaro, M I, primary, Grasso, D, additional, Ropolo, A, additional, Pardo, R, additional, Gonzalez, C D, additional, and Iovanna, J L, additional
- Published
- 2005
- Full Text
- View/download PDF
34. Assignment of the tumor protein p53 induced nuclear protein 2 (TP53INP2) gene to human chromosome band 20q11.2 by in situ hybridization
- Author
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Nowak, J., primary, Depetris, D., additional, Iovanna, J.-L., additional, Mattei, M.-G., additional, and Pébusque, M.-J., additional
- Published
- 2004
- Full Text
- View/download PDF
35. Assignment of tumor protein p53 induced nuclear protein 1 (TP53INP1) gene to human chromosome band 8q22 by in situ hybridization
- Author
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Nowak, J., primary, Tomasini, R., additional, Mattei, M.-G., additional, Azizi Samir, L.A., additional, Dagorn, J.-C., additional, Dusetti, N., additional, Iovanna, J.-L., additional, and Pébusque, M.-J., additional
- Published
- 2002
- Full Text
- View/download PDF
36. Genetic inactivation of the pancreatitis-inducible gene Nupr1 impairs PanIN formation by modulating KrasG12D-induced senescence.
- Author
-
Grasso, D, Garcia, M N, Hamidi, T, Cano, C, Calvo, E, Lomberk, G, Urrutia, R, and Iovanna, J L
- Subjects
PANCREATITIS ,NUCLEAR proteins ,TUMOR growth ,PANCREATIC diseases ,PRECANCEROUS conditions - Abstract
Nuclear protein 1 (Nupr1), a small chromatin protein, has a critical role in cancer development, progression and resistance to therapy. Previously, we had demonstrated that Nupr1 cooperates with Kras
G12D to induce pancreas intraepithelial neoplasias (PanIN) formation and pancreatic ductal adenocarcinoma development in mice. However, the molecular mechanisms by which Nupr1 influences Kras-mediated preneoplastic growth remain to be fully characterized. In the current study, we report evidence supporting a role for Nupr1 as a gene modifier of KrasG12D -induced senescence, which must be overcome to promote PanIN formation. We found that genetic inactivation of Nupr1 in mice impairs Kras-induced PanIN, leading to an increase in β-galactosidase-positive cells and an upregulation of surrogate marker genes for senescence. More importantly, both of these cellular and molecular changes are recapitulated by the results of mechanistic experiments using RNAi-based inactivation of Nupr1 in human pancreatic cancer cell models. In addition, the senescent phenotype, which results from Nupr1 inactivation, is accompanied by activation of the FoxO3a-Skp2-p27Kip1 -pRb-E2F pathway in vivo and in vitro. Thus, combined, these results show, for the first time, that Nupr1 aids oncogenic Kras to bypass senescence in a manner that cooperatively promotes PanIN formation. Besides its mechanistic importance, this new knowledge bears medical relevance as it delineates early pathobiological events that may be targeted in the future as a means to interfere with the formation of preneoplastic lesions early during pancreatic carcinogenesis. [ABSTRACT FROM AUTHOR]- Published
- 2014
- Full Text
- View/download PDF
37. Downregulation of IGF-I mRNA expression during postnatal pancreatic development and overexpression after subtotal pancreatectomy and acute pancreatitis in the rat pancreas
- Author
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Calvo, E L, primary, Bernatchez, G, additional, Pelletier, G, additional, Iovanna, J L, additional, and Morisset, J, additional
- Published
- 1997
- Full Text
- View/download PDF
38. Identification of a transcriptional regulatory region of the rat pancreatitis-associated protein I (PAP I) gene that confers tissue specificity
- Author
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Dusetti, N J, primary, Ortiz, E M, additional, Dagorn, J C, additional, and Iovanna, J L, additional
- Published
- 1995
- Full Text
- View/download PDF
39. Cloning, expression and chromosomal localization of the rat pancreatitis-associated protein III gene
- Author
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Dusetti, N J, primary, Frigerio, J M, additional, Szpirer, C, additional, Dagorn, J C, additional, and Iovanna, J L, additional
- Published
- 1995
- Full Text
- View/download PDF
40. Increased serum pancreatitis associated protein (PAP) concentration after longterm alcohol consumption: further evidence for regular subclinical pancreatic damage after heavy drinking?
- Author
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Nordback, I, primary, Jaakkola, M, additional, Iovanna, J L, additional, and Dagorn, J C, additional
- Published
- 1995
- Full Text
- View/download PDF
41. Developmental, Nutritional, and Hormonal Regulation of the Pancreatitis-Associated Protein I and III Gene Expression in the Rat Small Intestine
- Author
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Sansonetti, A., primary, Romeo, H., additional, Berthezene, P., additional, Scacchi, P., additional, Dusetti, N., additional, Keim, V., additional, Dagorn, J.-C., additional, and Iovanna, J. L., additional
- Published
- 1995
- Full Text
- View/download PDF
42. TAp73 is required for macrophage-mediated innate immunity and the resolution of inflammatory responses.
- Author
-
Tomasini, R, Secq, V, Pouyet, L, Thakur, A K, Wilhelm, M, Nigri, J, Vasseur, S, Berthezene, P, Calvo, E, Melino, G, Mak, T W, and Iovanna, J L
- Subjects
NATURAL immunity ,DNA damage ,TUMOR necrosis factors ,LIPOPOLYSACCHARIDES ,CYTOKINES ,PHAGOCYTOSIS - Abstract
The multiple isoforms of p73, a member of the p53 family, share the ability to modulate p53 activities but also have unique properties, leading to a complex and poorly understood functional network. In vivo, p73 isoforms have been implicated in tumor suppression (TAp73
−/− mice), DNA damage (ΔNp73−/− mice) and development (p73−/− mice). In this study, we investigated whether TAp73 contributes to innate immunity and septic shock. In response to a lethal lipopolysaccharide (LPS) challenge, TAp73−/− mice showed higher blood levels of proinflammatory cytokines and greater mortality than their wild-type littermates. In vitro, TAp73−/− macrophages exhibited elevated production of tumor necrosis factor alpha , interleukin-6 and macrophage inflammatory protein-2 as well as prolonged survival, decreased phagocytosis and increased major histocompatibility complex class II expression. Mice depleted of endogenous macrophages and reconstituted with TAp73−/− macrophages showed increased sensitivity to LPS challenge. These results suggest that macrophage polarization is altered in the absence of TAp73 such that maintenance of the M1 effector phenotype is prolonged at the expense of the M2 phenotype, thus impairing resolution of the inflammatory response. Our data indicate that TAp73 has a role in macrophage polarization and innate immunity, enhancing the action field of this important regulatory molecule. [ABSTRACT FROM AUTHOR]- Published
- 2013
- Full Text
- View/download PDF
43. PAP, a pancreatic secretory protein induced during acute pancreatitis, is expressed in rat intestine
- Author
-
Iovanna, J. L., primary, Keim, V., additional, Bosshard, A., additional, Orelle, B., additional, Frigerio, J. M., additional, Dusetti, N., additional, and Dagorn, J. C., additional
- Published
- 1993
- Full Text
- View/download PDF
44. Effects of Hypercholecystokininemia Produced by Pancreaticobiliary Diversion on Pancreatic Growth and Enzyme mRNA Levels in Starved Rats
- Author
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Chen, D., primary, Andersson, K., additional, Iovanna, J.-L., additional, Dagorn, J.-C., additional, and Håkanson, R., additional
- Published
- 1993
- Full Text
- View/download PDF
45. Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases.
- Author
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Orelle, B, primary, Keim, V, additional, Masciotra, L, additional, Dagorn, J C, additional, and Iovanna, J L, additional
- Published
- 1992
- Full Text
- View/download PDF
46. Pancreatic gene expression is altered during acute experimental pancreatitis in the rat
- Author
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Iovanna, J. L., primary, Keim, V., additional, Michel, R., additional, and Dagorn, J. C., additional
- Published
- 1991
- Full Text
- View/download PDF
47. P8 expression is induced in acinar cells during chronic pancreatitis.
- Author
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Motoo, Yoshiharu, Iovanna, Juan, Mallo, Gustavo, Su, Shi-Bing, Xie, Min-Jue, Sawabu, Norio, Motoo, Y, Iovanna, J L, Mallo, G V, Su, S B, Xie, M J, and Sawabu, N
- Abstract
The p8 gene is barely expressed in the normal pancreas, but is overexpressed in acute pancreatitis. To elucidate the dynamic expression of p8 mRNA and its significance in the course of chronic pancreatitis, we investigated the p8 expression in spontaneous chronic pancreatitis in the WBN/Kob rat as well as in humans and arginine-treated rat pancreatic acinar AR4-2J cells. p8 mRNA was significantly increased at 12 weeks when chronic pancreatitis first appeared in the WBN/Kob rats. p8 was immunolocalized in the acinar cell nuclei. Acinar cell apoptosis was significantly increased at 12 and 20 weeks in the WBN/Kob rats. In AR4-2J cells, p8 mRNA was significantly induced at 4 hr after arginine addition. Apoptosis of AR4-2J cells was not increased during the strong expression of p8 mRNA. These results suggest that p8 is induced in the acinar cells during chronic pancreatitis as the self-defence mechanism against proapoptotic insults. [ABSTRACT FROM AUTHOR]
- Published
- 2001
- Full Text
- View/download PDF
48. Lipopolysaccharide directly affects pancreatic acinar cells: implications on acute pancreatitis pathophysiology.
- Author
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Vaccaro, María, Calvo, Ezequiel, Suburo, Angela, Sordelli, Daniel, Lanosa, Gustavo, Iovanna, Juan, Vaccaro, M I, Calvo, E L, Suburo, A M, Sordelli, D O, Lanosa, G, and Iovanna, J L
- Abstract
We have explored whether lipopolysaccharide (LPS, endotoxin) induces pancreatic injury on pancreatic acinar cells both in vivo and in vitro. Wistar male rats were treated with four intraperitoneal injections of 10 mg/kg LPS, and AR4-2J cells were exposed to increasing doses of LPS. Expression of pancreatitis-associated-protein (PAP) mRNA was strongly induced in AR4-2J cells exposed to LPS, while amylase mRNA was reduced. LPS also induced apoptosis and expression of TNF-alpha, IL-1beta, and IL-8 mRNA in AR4-2J cells. The in vivo effect of LPS showed structural signs of cellular damage, including numerous cytoplasmic vacuoles, severe nuclear alterations, and high expression of PAP mRNA. This study demonstrated that LPS induced pancreatic damage by directly affecting the pancreatic acinar cells. The role of LPS in the pathophysiology of acute pancreatitis may be partly due to the effect LPS has on the acinar cell. [ABSTRACT FROM AUTHOR]
- Published
- 2000
- Full Text
- View/download PDF
49. Mechanism of PAP I gene induction during hepatocarcinogenesis: clinical implications.
- Author
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Dusetti, NJ, Montalto, G, Ortiz, EM, Masciotra, L, Dagorn, J-C, Iovanna, JL, Dusetti, N J, Ortiz, E M, and Iovanna, J L
- Published
- 1996
- Full Text
- View/download PDF
50. Temporary Pseudochronic Lesions During the Recovery of Acute Necrohemorrhagic Pancreatitis in Rabbits.
- Author
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Iovanna, J. L., Odaira, C., Berger, Z., and Sarles, .
- Published
- 1988
- Full Text
- View/download PDF
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