Search

The present report presents the outcomes of a transnational empirical survey conducted within the framework of the project “ReTrans – Working with Interpreters in Refugee Transit Zones: Capacity building and awareness-raising for higher education contexts”, which is carried out with the participation of partner universities from Austria, Greece, the Republic of North Macedonia, and Slovenia and is implemented with the support of the European Union's Erasmus+ programme.

AimOleocanthal and oleacein (OC/OL) have important in vitro and in vivo antitumor properties; however, there is no data about their anticancer activity in humans. The aim of this pilot study was to test if patients at early stage of chronic lymphocytic leukemia (CLL) could adhere to and tolerate an intervention with high OC/OL extra virgin olive oil (EVOO) and if this intervention could lead to any changes in markers related to the disease. MethodsA pilot dietary intervention (DI) was made in patients with CLL in Rai stages 0-II who did not follow any treatment (NCT04215367). In the first intervention (DI1), 20 CLL patients were included in a blind randomized study and were separated into two groups. One group (A) of 10 patients consumed 40 ml/day of high OC/OL-EVOO (416 mg/Kg OC and 284 mg/kg OL) for 3 months. A second group (B) of 10 patients consumed 40 ml/day of low OC/OL (82 mg/kg OC and 33 mg/kg OL) for 3 months. After a washout period of 9-12 months, a second intervention (DI2) only with High OC/OL-EVOO for 6 months was performed with 22 randomly selected patients (16 from the DI1 (8 from each group) and 6 new). Hematological, biochemical, and apoptotic markers were analyzed in the serum of the patients. In addition, cellular proliferation and apoptosis markers were studied in isolated proteins from peripheral blood mononuclear cells. ResultsThe results of the DI1 showed beneficial effects on hematological and apoptotic markers only with High OC/OL-EVOO. During the DI2, a decrease in the white blood cell and lymphocyte count was observed (p

The purpose of the book is to present systematically the basic theoretical and practical aspects of interpreting as an autonomous scientific discipline of Translation Studies and a professional activity. Its specific objective is to provide students and aspiring interpreters with the theoretical knowledge, practical skills and professional values needed to understand and apply in practice the complex process of interpreting: from the phase of preparation to the phase following the conclusion of the interpreting process. As far as the theoretical content is concerned, the book presents a critical overview of the general principles and fundamental issues of interpreting, such as how interpreting is defined and how it differs from related activities, in what categories it is distinguished, what theoretical considerations contributed to its development, in what settings and what modes of interpreting interpreters work, what the relevant requirements are, what the rules of professional ethics are and how the profession is affected by modern technological developments. As far as the practical aspects of the book are concerned, students become familiar with the basic skills of interpreting. The issues addressed from that point of view are how interpreting is performed in practice, what cognitive processes are involved, what techniques are applied to each mode of interpreting, what the potential roles and tasks of interpreters are and how they should behave in the performance of their duties. The aforementioned issues are addressed in six chapters, each one of which is followed by several comprehension questions and/or exercises for practical application, using, where possible, authentic material., Σκοπός του βιβλίου είναι η συστηματική παρουσίαση των βασικών θεωρητικών και πρακτικών διαστάσεων της διερμηνείας ως αυτόνομου επιστημονικού κλάδου των Μεταφραστικών Σπουδών και επαγγελματικής δραστηριότητας. Ο ειδικότερος στόχος του είναι να προσφέρει στους φοιτητές και επίδοξους διερμηνείς τις απαραίτητες θεωρητικές γνώσεις, πρακτικές ικανότητες και επαγγελματικές αξίες, ώστε να είναι σε θέση να κατανοούν και να εφαρμόζουν στην πράξη την περίπλοκη και σύνθετη διαδικασία της διερμηνείας: από τα πρώτα βήματα της προετοιμασίας μέχρι το στάδιο που έπεται της ολοκλήρωσης του διερμηνευτικού εγχειρήματος. Σε επίπεδο θεωρίας, το περιεχόμενο του βιβλίου συνίσταται στην κριτική επισκόπηση των γενικών αρχών και θεμελιωδών ζητημάτων της διερμηνείας, όπως πώς ορίζεται η διερμηνεία και σε τι διαφέρει από συγγενείς δραστηριότητες, σε ποιες κατηγορίες διακρίνεται, ποιες θεωρήσεις συνέβαλαν στην εξέλιξή της, σε ποια περιβάλλοντα και με ποιο είδος διερμηνείας εργάζονται οι διερμηνείς, ποιες οι εκάστοτε απαιτήσεις, τι ορίζει η δεοντολογία του επαγγέλματος και πώς επηρεάζεται αυτό από τις σύγχρονες τεχνολογικές εξελίξεις. Σε πρακτικό επίπεδο, το περιεχόμενο του βιβλίου έγκειται στην εξοικείωση των φοιτητών με τις βασικές δεξιότητες της διερμηνείας. Τα ερωτήματα που εξετάζονται εδώ είναι πώς γίνεται η διερμηνεία, ποια γνωσιακή διαδικασία ακολουθείται, ποιες τεχνικές εφαρμόζονται στο κάθε είδος διερμηνείας, ποιους ρόλους και ποια καθήκοντα καλούνται να αναλάβουν οι διερμηνείς και πώς πρέπει να συμπεριφέρονται κατά την άσκηση του επαγγέλματός τους. Η παραπάνω θεματολογία εξετάζεται σε έξι κεφάλαια, στο τέλος των οποίων παρατίθενται ερωτήσεις κατανόησης του περιεχομένου τους ή/και ασκήσεις για πρακτική εφαρμογή, με τη χρήση, όπου είναι δυνατόν, αυθεντικού υλικού.

Introduction The anti-inflammatory effect of macrolides prompted the study of oral clarithromycin in moderate COVID-19. Methods An open-label non-randomized trial in 90 patients with COVID-19 of moderate severity was conducted between May and October 2020. The primary endpoint was defined at the end of treatment (EOT) as no need for hospital re-admission and no progression into lower respiratory tract infection (LRTI) for patients with upper respiratory tract infection and as at least 50% decrease of the respiratory symptoms score without progression into severe respiratory failure (SRF) for patients with LRTI. Viral load, biomarkers, the function of mononuclear cells and safety were assessed. Results The primary endpoint was attained in 86.7% of patients treated with clarithromycin (95% CIs 78.1-92.2%); this was 91.7% and 81.4% among patients starting clarithromycin the first 5 days from symptoms onset or later (odds ratio after multivariate analysis 6.62; p 0.030). The responses were better for patients infected by non-B1.1 variants. Clarithromycin use was associated with decreases in circulating C-reactive protein, tumour necrosis factor-alpha and interleukin (IL)-6; by increase of production of interferon-gamma and decrease of production of interleukin-6 by mononuclear cells; and by suppression of SARS-CoV-2 viral load. No safety concerns were reported. Conclusions Early clarithromycin treatment provides most of the clinical improvement in moderate COVID-19.

Introduction/Objectives: Periodontitis comprises of a wide range of inflammatory conditions of the gums leading to soft tissue damage and attachment loss. The initiation of periodontitis constitutes a rather complex disease pathogenesis which is based on pathogenic shifts of the oral microbiota combined with the host-microbiome interactions. The severity of the periodontitis is multifactorial depending on genetic, environmental, as well as host immunity factors. Data and sources: To make an inclusive analysis on the periodontitis therapeutics, reading of the recent relevant literature was carried out using the MEDLINE/PubMed database, Google Scholar and the NIH public online database for clinical trials (http://www.clinicaltrials.gov). Conclusions: Tackling the inflammation associated periodontal defects can be succeeded with conventional therapy or resective and regenerative treatment. To date, the mechanical removal of the supragingival and subgingival biofilm is considered the “gold standard” of periodontal therapy in combination with the use of antibacterial compounds. The antimicrobial resistance phenomenon tends to turn all the currently applied antibacterials into “endangered species”. Ongoing efforts through the conduct of clinical trials should be focused on understanding the advantages of modern approaches in comparison to traditional therapies.

Purpose: To estimate the roles of triglyceride/high-density lipoprotein cholesterol (TG/HDL) ratio and uric acid in predisposition for metabolic syndrome (MetS) and its components in healthy children. Methods: Anthropometric and biochemical analyses were performed on 110 children, aged 5 to 12 years, from the Greek county of Laconia. The children were studied as a whole population and in separate groups according to age and predisposition to MetS after taking into consideration International Diabetes Federation criteria, body mass index, and lipid profile. Results: Seventeen percent of children exhibited predisposition to MetS, while 39.1% had TG/HDL ratio >1, and 3.64% had high level of uric acid. According to a receiver operating characteristic curve analysis, the relative probability for MetS predisposition sextupled when TG/HDL ratio was >= 1 (odds ratio [OR], 5.986; 95% confidence interval [CI], 1.968-18.205). Children in the total population and those aged < 9 years had a greater probability for increased low-density lipoprotein (LDL) cholesterol (OR, 3.614; 95% CI, 1.561-8.365) when TG/HDL ratio was >= 1. The TG/HDL ratio was positively correlated with body mass index (BMI) (P=0.035) in children without MetS, cholesterol in the total population (P=0.06) and children >= 9 years old (P=0.026), and with LDL in the total population and both age groups (P=0.001). The TG/HDL ratio was also positively correlated with alanine aminotransferase in the total population (P=0.033) and gamma-glutamyl transferase in most studied groups (P

Purpose: To investigate the effect of lifestyle habits in childhood Metabolic Syndrome (MTS). Design and Methods: Descriptive correlation study with 480 participants (5-12 years old) using a specially designed questionnaire was conducted. Anthropometric and biochemical analyses were performed. Results: Fifteen percent of children exhibited predisposition for MTS. Regarding sleep habits, logistic regression analysis (LRA) showed that hour of sleep -before 22: 00- was associated with decreased waist circumference (WC%) (p = .026). Midday siesta was negatively correlated with systolic (SBP) (p = .001) and diastolic blood pressure (DBP) (p = .046). In children without MTS, lack of sleep and night time sleep was positively correlated with DBP (p = .044) and fasting blood glucose (FBG) (p = .005). Regarding nutrition habits, fast food consumption was positively correlated with SBP (p = .006) and meat consumption was positively correlated with both Body Mass Index% (BMI%) (p = .038) and WC% (p = .023). LRA showed that fruit (p = .001) and legume (p = .040) consumption was associated with decreased FBG; fish consumption with decreased Low Density Lipoprotein (LDL) cholesterol (p = .031), vegetable (p = .054) and cereal consumption (p = .012) with decreased DBP. In children with MTS, fruits were associated with increased FBG (p = .034). In children without MTS, meat consumption was associated with increased LDL (p = .024), cereal with increased WC% (p = .002) and olive products with increased High Density Lipoprotein (HDL) cholesterol and BMI% (p = .037). Conclusions: The adoption of both balanced diet and sleep habits seemed to be crucial for the prevention of MTS. Practice Implications: Clinical health nurses could develop and implement preventive intervention programs in order to avoid metabolic complications in adulthood. (C) 2018 Elsevier Inc. All rights reserved.