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32 results on '"Inositol 1,4,5-Trisphosphate genetics"'

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1. IP 3 -mediated gating mechanism of the IP 3 receptor revealed by mutagenesis and X-ray crystallography.

2. Structural insights into endoplasmic reticulum stored calcium regulation by inositol 1,4,5-trisphosphate and ryanodine receptors.

3. The G protein α subunit variant XLαs promotes inositol 1,4,5-trisphosphate signaling and mediates the renal actions of parathyroid hormone in vivo.

4. Designer small molecules to target calcium signalling.

5. β-Cell Ca(2+) dynamics and function are compromised in aging.

6. IP3-mediated STIM1 oligomerization requires intact mitochondrial Ca2+ uptake.

7. Antisense oligonucleotides targeting parasite inositol 1,4,5-trisphosphate receptor inhibits mammalian host cell invasion by Trypanosoma cruzi.

8. Phosphorylated K-Ras limits cell survival by blocking Bcl-xL sensitization of inositol trisphosphate receptors.

9. Filamin and phospholipase C-ε are required for calcium signaling in the Caenorhabditis elegans spermatheca.

10. Adenine induces differentiation of rat hepatic stellate cells.

11. Vav1 oncogenic mutation inhibits T cell receptor-induced calcium mobilization through inhibition of phospholipase Cγ1 activation.

12. Mechanism of all-trans-retinal toxicity with implications for stargardt disease and age-related macular degeneration.

13. Phospholipase Cγ-2 and intracellular calcium are required for lipopolysaccharide-induced Toll-like receptor 4 (TLR4) endocytosis and interferon regulatory factor 3 (IRF3) activation.

14. Induction of intracellular calcium concentration by environmental benzo(a)pyrene involves a β2-adrenergic receptor/adenylyl cyclase/Epac-1/inositol 1,4,5-trisphosphate pathway in endothelial cells.

15. Tumor progression locus 2 mediates signal-induced increases in cytoplasmic calcium and cell migration.

16. Isoform-specific regulation of the inositol 1,4,5-trisphosphate receptor by O-linked glycosylation.

17. Critical role for CD38-mediated Ca2+ signaling in thrombin-induced procoagulant activity of mouse platelets and hemostasis.

18. Human inositol 1,4,5-trisphosphate 3-kinase isoform B (IP3KB) is a nucleocytoplasmic shuttling protein specifically enriched at cortical actin filaments and at invaginations of the nuclear envelope.

19. Regulation of inositol 1,4,5-trisphosphate receptors by cAMP independent of cAMP-dependent protein kinase.

20. Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1.

21. Phosphoinositide phosphatases in a network of signalling reactions.

22. Biochemical analysis of inositol phosphate kinases.

23. Targeted expression of Ip3 sponge and Ip3 dsRNA impaires sugar taste sensation in Drosophila.

24. Nucleotide sequence analysis of the binding site on the inositol 1,4,5-trisphosphate type-1 receptor in bipolar disorder -- a negative study.

25. Intracellular Ca(2+) release mechanisms: multiple pathways having multiple functions within the same cell type?

26. Ca2+ and calmodulin differentially modulate myo-inositol 1,4, 5-trisphosphate (IP3)-binding to the recombinant ligand-binding domains of the various IP3 receptor isoforms.

27. Type 1 inositol 1,4,5-trisphosphate receptor knock-out mice: their phenotypes and their meaning in neuroscience and clinical practice.

28. Expression of the ryanodine receptor type 3 in skeletal muscle. A new partner in excitation-contraction coupling?

29. Molecular cloning of a cDNA for the human inositol 1,4,5-trisphosphate receptor type 1, and the identification of a third alternatively spliced variant.

30. In situ hybridization of mRNA expression for IP3 receptor and IP3-3-kinase in rat brain after transient focal cerebral ischemia.

31. A new splice variant of the inositol-1,4,5-triphosphate (IP3) receptor.

32. Substance P induces inositol 1,4,5-trisphosphate and intracellular free calcium increase in cultured normal human epidermal keratinocytes.

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