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This new volume in the Reproductive Medicine for Clinicians series focuses on the practical clinical impact of problems linked to infertility, discussing topics such as luteal support in ART cycles, ovulation induction using pulsatile administration of GnRH, how to deal with the metabolic changes in PCOS, treatment to restore fertility in endometriosis and how to improve implantation, which are common aspects of daily clinical practice.It also addresses significant novel areas like the biological clock in human reproduction, reproduction at advanced parental age and medical and social egg freezing, offering valuable insights for patients and their doctors. Further, the book covers various areas of growing importance, such as how to access the uterine cavity; the future of imaging in reproduction; non-invasive prenatal testing; ART and male infertility; as well as breast cancer and fertility preservation.Last but not least, it examines the medical, ethical and legal aspects of a number of challenges for current and future reproductive medicine, including uterine transplantation and human genetic modification.Bringing together updates on some of the most important problems in reproductive medicine and also covering ethical and legal bases, this book offers an overview of potential treatments for infertility. As such, it is a valuable resource for gynecologists, obstetricians, endocrinologists and all specialists dealing with reproductive health.

A comprehensive survey of the use of ultrasound in management of infertile patients is presented in this publication. Particular atten-tion is given to recently developed techniques such as assessment of endometrial changes, ovarian blood flow measurements, and per-cutaneous oocyte retrieval for in vitro fertilization. The very re-cent technique of transvaginal sonography is presented and richly illus-trated with original results obtained in biopsy-guided oocyte re-trieval, and in the precise delineation of follicle size and number for infertility treatment. Guidance in the interpretation of ultrasonic findings, which include potential limitations and pitfalls, is provided in each chapter. Researchers and practitioners interested in the management of infertile patients will find this volume indispensable.

Different genetic diagnostic and treatment options are used worldwide to improve routine IVF procedures for the benefit of patients. This handbook updates the new genetic diagnostic technologies that have been translated to practice aiming to improve outcomes in the clinic and have a healthy baby at home. Chapters cover the use of genetic technologies in a personalized manner to unravel the possible genetic risks for the couple wishing to conceive, in terms of sperm, the embryo, the endometrium, miscarriage, and finally the fetus.

The field of infertility research and practice is one of continuous innovation and change, but alongside the increasing sophistication of assisted reproductive techniques there is as strong a need as ever for clinical experience and expertise and common practical sense to inform diagnosis and clinical decision making. Now in its fourth edition, Inf

The authors of this book have a goal-to describe the management of infertility from the perspective of physiology and anatomy gone awry. To accomplish this goal, the chapters devoted to the causes of infertil­ ity begin with a description of the normal structure and function of the organ or system causing the infertility. We believe that under­ standing the normal will result in rational and effective diagnosis and treatment of infertility. Our intent is that this book be a useful re­ source for those who care for infertile couples. For an infertile couple, success is the delivery of a normal and healthy infant. Chapters that describe the causes and treatment of habitual abortion and the reproductive performance of previously infertile couples emphasize the hazards that exist between conception and birth. Our environment is one of these hazards, one that may also affect reproduction before conception. A chapter is devoted to a de­ scription of environmental agents that affect reproduction, the mech­ anisms of their effect, and methods to predict those present and future environmental agents which might also affect reproduction.

A little over 12 years ago I wrote a small volume entitled Infertility. It seemed to me at that time that significant advances in the field called for the publication of such a volume. The following is from the preface to that volume: During the past 15 years considerable progress has been made in the field of infertility diagnosis and management. It is perhaps a paradox that much of this increased knowledge has come about because of Western medicine's preoccupation with the search for a means to control reproduction. As a result, we have achieved new insights into the physiologic mechanisms involved in reproduction, and we have found better methods for measuring physiologic changes in reproductive health and disease. To these advances can be added improvements in the utilization of endoscopic and surgical techniques, in the diagnosis and treatment of infections and endometriosis, and in the treatment of hormonal disorders. During this period, too, through workshops and conferences and in journals and texts, these latest advances have been made available to physi­ cians, an outstanding example being the two volumes of Progress in Infer­ tility, edited by Drs. Jan Behrman and Robert Kistner. As necessary as these publications are, they do not offer an overall view of infertility diag­ nosis and management.

This book entitled “Infertility: Diagnosis, Management and IVF” explains the detailed diagnosis of male and female infertility, treatment of infertility with IVF, and various aspects of the IVF laboratory including protocols, handling of embryo transfers, freezing and biopsy for preimplantation genetic screening. It also covers the management of IVF programs, practice guidelines, ethical and social aspects of infertility and IVF, etc. Infertility diagnosis, management and the treatment options have drastically improved and diagnosis method has been refined the implementation of vitrification techniques that have aided the cryopreservation of embryos, eggs and blastocysts. This book consists of eight sections which cover various aspects of infertility and its treatment. Infertility and male factor infertility are explained briefly in the first and second section. The section three covers aspects regarding female factor infertility such as evaluation, diagnosis, treatment, etc., of female infertility. The in vitro fertilization procedures, protocols, female reproductive aging, etc., are discussed briefly in the fourth section. Section five and six details about the practice guidelines for the treatment of patients with infertility and assisted reproductive technology and birth defects. The regulation of the assisted reproductive technology laboratory and emotional and social aspects of infertility treatment are finally described in the eighth section.

Nowhere has the impact of ultrasonography been more dramatic than in reproductive medicine, particularly in the diagnosis of female and male infertility, the management of assisted reproductive procedures and the monitoring of early pregnancy. This authoritative textbook encompasses the complete role of ultrasonography in the evaluation of infertility and assisted reproduction. Covering every indication for ultrasonography in assisted reproductive technology, this will prove an invaluable resource in the evaluation of the infertile patient and optimization of the outcome of treatment. The interpretation of images to improve fertility and reproductive success is emphasized throughout. Ultrasonography in Reproductive Medicine and Infertility is essential reading for clinicians working both in IVF clinics and in office practice. It will be particularly useful to gynecologists, infertility specialists, ultrasonographers and radiologists working in reproductive endocrinology and infertility, assisted reproductive technology, ultrasonography and radiology.