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2023 SEP 23 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators publish new report on phototherapy. According to news reporting originating from [...]

2023 JAN 5 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- Investigators publish new report on Surgery - Cesarean Section. According to news reporting from [...]

2022 JUL 14 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- According to news reporting based on a preprint abstract, our journalists obtained the following [...]

2021 APR 3 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Current study results on neonatal jaundice have been published. According to news [...]

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jtcvs.2008.08.044 Byline: Colleen E. Gruenwald (b), Brian W. McCrindle (c), Lynn Crawford-Lean (b), Helen Holtby (d), Christopher Parshuram (e), Patricia Massicotte (f), Glen Van Arsdell (a) Abbreviations: ACT, activated clotting time; CBS, Canadian Blood Services; CCCU, cardiac critical care unit; CPB, cardiopulmonary bypass; DHCA, deep hypothermic circulatory arrest; IL-8, interleukin 8; PRBC, packed red blood cell; RFWB, reconstituted fresh whole blood; TNF, tumor necrosis factor Abstract: This study compared the effects of reconstituted fresh whole blood against standard blood component therapy in neonates undergoing cardiac surgery. Author Affiliation: (a) Labatt Family Heart Centre, Department of Cardiovascular Surgery, The Hospital for Sick Children and The University of Toronto, Toronto, Ontario, Canada (b) Labatt Family Heart Centre, Department of Perfusion, The Hospital for Sick Children and The University of Toronto, Toronto, Ontario, Canada (c) Labatt Family Heart Centre, Department of Cardiology, The Hospital for Sick Children and The University of Toronto, Toronto, Ontario, Canada (d) Labatt Family Heart Centre, Department of Anaesthesia, The Hospital for Sick Children and The University of Toronto, Toronto, Ontario, Canada (e) Labatt Family Heart Centre, Department of Critical Care Medicine, The Hospital for Sick Children and The University of Toronto, Toronto, Ontario, Canada (f) Labatt Family Heart Centre, Department of Pediatrics, The Hospital for Sick Children and The University of Toronto, Toronto, Ontario, Canada Article History: Received 24 January 2008; Revised 9 July 2008; Accepted 28 August 2008 Article Note: (footnote) This work was funded by The Hospital for Sick Children Foundation.

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jtcvs.2007.03.007 Byline: Joseph Atallah (a), Ari R. Joffe (a), Charlene M.T. Robertson (a)(c), Norma Leonard (b), Patricia M. Blakley (d), Alberto Nettel-Aguirre (e)(f), Reg S. Sauve (e), David B. Ross (g), Ivan M. Rebeyka (g) Abbreviations: CCS, complex cardiac surgery; CHD, congenital heart disease; del22q11.2, deletion 22q11.2; IAA, interrupted aortic arch; IQ, intelligence quotient; MDI, mental developmental index; PA, pulmonary atresia; PDI, psychomotor developmental index; SD, standard deviation; TA, truncus arteriosus; TOF, tetralogy of Fallot; VSD, ventricular septal defect Abstract: Neonatal complex cardiac surgery carries a significant risk for adverse neurodevelopmental outcome. We hypothesized this risk to be higher in patients with deletion 22q11.2. Author Affiliation: (a) Departments of Pediatrics (b) Medical Genetics (g) Surgery (c) University of Alberta, Edmonton, Alberta, Canada; Neonatal and Infant Follow-up Clinic (d) Glenrose Rehabilitation Hospital, Edmonton, Alberta, Canada; Department of Pediatrics (e) University of Saskatchewan, Saskatoon, Saskatchewan, Canada; Department of Pediatrics (f) University of Calgary, Calgary, Alberta, Canada; Biostatistician (h) Research Methods Team, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada; D. Moddemann, Winnipeg, Manitoba, Canada; A. Ninan, Regina, Saskatchewan, Canada Article History: Received 19 December 2006; Revised 2 February 2007; Accepted 14 March 2007 Article Note: (footnote) Financial support was initially provided by the Glenrose Rehabilitation Hospital research trust fund, with ongoing funding from the Registry and Follow-up of Complex Pediatric Therapies Project, Alberta Health and Wellness.

Byline: Erich Hafner, Walter Sterniste, Alexander Rosen, Katharina Schuchter, Marion Plattner, Friederike Asboth, Karl Philipp Keywords: Group B streptococci; neonatal infection Abstract: OBJECTIVE: The objective was to evaluate whether the rate of neonatal group B streptococcal infection could be reduced by screening for group B streptococci during the third trimester of pregnancy. STUDY DESIGN: Two periods in which different screening and treatment protocols were applied were compared. In period A all mothers showing high-risk factors were given peripartal antibiotic coverage. In period B vaginal and rectal smears were routinely obtained in gestational week 34 and cultured for group B streptococci. If culture results were positive, the woman received peripartal antibiotics. The incidence of group B streptococcal infections and the number of peripartal antibiotic doses were established by comparing 3700 neonates (3623 mothers) in period A with 3648 neonates (3569 mothers) in period B. RESULTS: In period A, 20 group B streptococcal infections were recorded. Of these, 5 were severe to life-threatening. In period B, 4 group B streptococcal infections were observed. Two were severe and occurred in neonates born before the mothers could be screened. Another 2 were mild and occurred in neonates whose mothers had negative screening test results. The reduction was significant by the I.sup.2 test (I.sup.2 = 9.19, Yates' corrected P = .0024). The rates of peripartal antibiotic treatment were 11.9% in period A and 14.5% in period B. CONCLUSION: Although no neonate died of group B streptococcal sepsis in either of the 2 periods, the protocol used in period B clearly reduced the incidence of group B streptococcal infection. The number of peripartal antibiotic doses required was not much higher than in period A. Screening for group B streptococci in week 34 seems to be a valuable contribution to further improvement of neonatal outcome. (Am J Obstet Gynecol 1998;179:677-81.) Author Affiliation: Vienna, Austria Article History: Received 10 September 1997; Revised 2 March 1998; Accepted 26 March 1998 Article Note: (footnote) [star] From the Ludwig Boltzmann Institute for Clinical Obstetrics and Gynecology Department of Obstetrics and Gynecologya and the Departments of Pediatricsb and Pathology,c Donauspital am SMZ-Ost., [star][star] Reprint requests: Erich Hafner, MD. Gynakologische und Geburtshilfliche Abteilung Donauspital am SMZ-Ost, LangobardenstraAe 122, A-1220 Vienna, Austria., a 0002-9378/98 $5.00 + 0 6/1/90549

Byline: Harald Leitich, Christian Egarter, Klaus Reisenberger, Alexandra Kaider, Peter Berghammer Keywords: Preterm premature rupture of fetal membranes; antibiotic therapy; glucocorticoid therapy; metaanalysis; randomized clinical trial Abstract: OBJECTIVE: This study was performed to investigate whether the demonstrated beneficial effects of antibiotics on maternal and neonatal morbidity are altered when glucocorticoids are part of the treatment of preterm premature rupture of membranes. STUDY DESIGN: We performed a metaanalysis of five published, randomized trials of antibiotic treatment in preterm premature rupture of membranes in which glucocorticoids were used as additional treatments and compared the results with those of a previously published metaanalysis of antibiotic treatment in preterm premature rupture of membranes, which excluded studies with concomitant glucocorticoids. Primary outcomes included chorioamnionitis, postpartum endometritis, neonatal sepsis, respiratory distress syndrome, intraventricular hemorrhage, necrotizing enterocolitis, and neonatal mortality. A logistic regression analysis was performed to test whether glucocorticoids significantly influenced the effect of antibiotic treatment. RESULTS: Among the 509 patients from five trials on antibiotic and glucocorticoid treatment published between 1986 and 1993 antibiotic therapy did not show any significant effect on any of the outcomes analyzed. In contrast, antibiotic therapy without concomitant use of glucocorticoids significantly reduced the odds of chorioamnionitis, postpartum endometritis, neonatal sepsis, and intraventricular hemorrhage by 62%, 50%, 68%, and 50%, respectively. The logistic regression analysis showed that glucocorticoids significantly diminished the effect of antibiotic treatment on chorioamnionitis and neonatal sepsis. CONCLUSION: Glucocorticoids appear to diminish the beneficial effects of antibiotics in the treatment of preterm premature rupture of membranes. A careful selection of patients who are likely to benefit from both therapies is therefore recommended. (Am J Obstet Gynecol 1998;178:899-908.) Author Affiliation: Vienna, Austria Article History: Received 14 July 1997; Revised 31 October 1997; Accepted 20 November 1997 Article Note: (footnote) [star] From the Department of Obstetrics and Gynecologya and the Department of Medical Computer Sciences, Section of Clinical Biometrics,b University of Vienna., [star][star] The database searches were funded by the Austrian Ministry of Science., a Reprint requests: Harald Leitich, MD, MSc, Department of Obstetrics and Gynecology, University of Vienna, Wahringer Gurtel 18-20, 1090 Vienna, Austria., aa 6/1/87732

By a News Reporter-Staff News Editor at Women's Health Weekly -- Investigators publish new report on Women's Health. According to news reporting originating in Osaka, Japan, by NewsRx journalists, research [...]

By a News Reporter-Staff News Editor at Women's Health Weekly -- A new study on Obstetrics and Gynecology is now available. According to news reporting originating in St. Louis, Missouri, [...]

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ajog.2008.09.022 Byline: Jeffrey M. Lubow, Helen Y. How, Mounira Habli, Rose Maxwell, Baha M. Sibai Keywords: delivery indications; late preterm birth; neonatal complications Abstract: The objective of the study was to evaluate the indications for late preterm birth and compare outcomes by gestational age among late preterm (34-36 weeks) and term ([greater than or equal to] 37 weeks) neonates at our institution. Author Affiliation: Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH Article History: Received 10 July 2008; Revised 2 September 2008; Accepted 17 September 2008 Article Note: (footnote) Reprints not available from the authors.

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ajog.2009.02.038 Byline: Kristine Y. Lain (a)(b), Matthew J. Garabedian (a), Ashi Daftary (c), Arun Jeyabalan (c) Keywords: fetal fat mass; gestational diabetes; glyburide; randomized clinical trial; treatment Abstract: We hypothesized that body composition would be similar among neonates of women with gestational diabetes (GDM) treated with glyburide or insulin. Author Affiliation: (a) Department of Obstetrics and Gynecology, University of Kentucky College of Medicine, Lexington, KY (b) Department of Medicine, University of Kentucky College of Medicine, Lexington, KY (c) Magee-Womens Research Institute and the Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA Article History: Received 22 November 2008; Revised 3 February 2009; Accepted 26 February 2009 Article Note: (footnote) This work was supported by Grants from the American Association of Obstetricians and Gynecologists Foundation and Magee-Womens Health Foundation (both to K.Y.L.)., Cite this article as: Lain KY, Garabedian M, Daftary A, et al. Neonatal adiposity following maternal treatment of gestational diabetes with glyburide compared to insulin. Am J Obstet Gynecol 2009;200:501.e1-501.e6.