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41 results on '"Indovina D"'

1. Hepatic Steatosis and Portal Hypertension with Presinusoidal Obstruction

Author

Greco F, Muratori F, Cesano L, Vaccarino A, Livio Chiandussi, and Indovina D

Subjects
medicine.medical_specialty, Cirrhosis, Hepatology, business.industry, Portal venous pressure, Fatty liver, Gastroenterology, Hemodynamics, medicine.disease, Internal medicine, medicine, Portal hypertension, Steatosis, business, Splanchnic
Abstract

Summary A patient is reported in whom a grossly enlarged fatty liver without cirrhosis was observed in association with portal hypertension. A careful investigation of the splanchnic hemodynamics showed a presinusoidal or sinusoidal obstruction. We suggest that the presinusoidal block was secondary to compression of intrahepatic portal radicles and/or sinusoids by fat laden parenchymal cells.

Published
1963
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2. Effect of drug infusion on the splanchnic circulation. I. Angiotensin infusion in normal and cirrhotic subjects

Author

Vaccarino A, Cesano L, Greco F, Muratori F, Indovina D, and Livio Chiandussi

Subjects
Liver Cirrhosis, Cardiac output, Mean arterial pressure, Angiotensins, Splanchnic Circulation, business.industry, Portal venous pressure, Blood flow, medicine.disease, General Biochemistry, Genetics and Molecular Biology, Portal System, Anesthesia, Renin–angiotensin system, Blood Circulation, Hypertension, Hypertension, Portal, Medicine, Portal hypertension, Humans, Splanchnic, business
Abstract

SummaryThe effect on splanchnic circulation of a constant infusion of angiotensin was investigated on 8 normal subjects and 7 cirrhotic patients with portal hypertension. The rate of angiotensin infusion was varied to obtain a rise in mean arterial pressure of 50% and ranged from 0.3 to 0.5 γ/kg/min. Both cardiac output and estimated hepatic blood flow were reduced, respectively, by 17.5 and 23.9%. Portal venous pressure remained unchanged. Splanchnic resistances increased by 118.3%. These effects were present in the subjects of both groups.

Published
1963

3. Effect of drug infusion on splanchnic circulation. II. Serotonin infusion in normal and cirrhotic subjects

Author

Muratori F, L. Chiandussi, Cesano L, Indovina D, Greco F, and Vaccarino A

Subjects
Cardiac output, Serotonin, business.industry, Splanchnic Circulation, Portal venous pressure, Blood flow, medicine.disease, General Biochemistry, Genetics and Molecular Biology, Portal System, Blood pressure, Anesthesia, Blood Circulation, Hypertension, Hypertension, Portal, Medicine, Portal hypertension, Humans, business, Splanchnic
Abstract

SummaryThe effect on splanchnic circulation of a serotonin constant infusion was investigated on 8 normal subjects and 8 cirrhotic patients with portal hypertension. The rate of serotonin infusion was of 30 γ/kg/min.Mean arterial pressure, cardiac output and portal venous pressure were not significantly affected.The estimated hepatic blood flow was reduced by 9.2% (P

Published
1963

9. Prolactin secretion in polycystic ovary syndrome (PCO): correlation with the steroid pattern.

Author

Carmina E, Rosato F, Maggiore M, Gagliano AM, Indovina D, and Jannì A

Subjects
17-alpha-Hydroxyprogesterone, Adolescent, Adult, Dehydroepiandrosterone blood, Estradiol blood, Estrone blood, Female, Follicle Stimulating Hormone blood, Humans, Hydroxyprogesterones blood, Luteinizing Hormone blood, Polycystic Ovary Syndrome blood, Prolactin blood, Testosterone blood, Thyrotropin-Releasing Hormone pharmacology, Polycystic Ovary Syndrome physiopathology, Prolactin metabolism
Abstract

To evaluate the prevalence of hyperprolactinaemia in PCO patients and its possible correlation with a steroid pattern, we studied prolactin secretion (basal and after TRH stimulation) in 40 women affected by typical PCO. LH, FSH, testosterone, oestradiol, oestrone, DHEA-s and 17-OHP serum levels were also evaluated. Twenty-one patients had prolactin (Prl) values in the normal range both in baseline conditions and after TRH stimulation; 10 patients had normal basal values of Prl but an exaggerated response to TRH stimulation; 9 patients had high Prl basal values and an exaggerated response to TRH. The presence of hyperprolactinaemia was associated with increased serum levels of oestrone (P less than 0.01), DHEA-s (P less than 0.01) and 17-OHP (P less than 0.05). In conclusion, hyperprolactinaemia is as relatively frequent condition which affects almost half the patients suffering from PCO and is probably related to an increase of serum oestrogens, mostly oestrone. Moreover, in patients with PCO and hyperprolactinaemia, the production of some other steroids is also affected.

Published
1984
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