Search

Your search keyword '"Inaba K"' showing total 2,737 results
Start Over Author "Inaba K"
2,737 results on '"Inaba K"'

1. Effect of ground-state deformation on the Isoscalar Giant Monopole Resonance and the first observation of overtones of the Isoscalar Giant Quadrupole Resonance in rare-earth Nd isotopes

Author

Abdullah, M., Bagchi, S., Harakeh, M. N., Akimune, H., Das, D., Doi, T., Donaldson, L. M., Fujikawa, Y., Fujiwara, M., Furuno, T., Garg, U., Gupta, Y. K., Howard, K. B., Hijikata, Y., Inaba, K., Ishida, S., Itoh, M., Kalantar-Nayestanaki, N., Kar, D., Kawabata, T., Kawashima, S., Khokhar, K., Kitamura, K., Kobayashi, N., Matsuda, Y., Nakagawa, A., Nakamura, S., Nosaka, K., Okamoto, S., Ota, S., Pal, S., Pramanik, R., Roy, S., Weyhmiller, S., Yang, Z., and Zamora, J. C.

Subjects
Nuclear Experiment, Nuclear Theory
Abstract

The strength distributions of the Isoscalar Giant Monopole Resonance (ISGMR) and Isoscalar Giant Quadrupole Resonance (ISGQR) in 142,146-150Nd have been determined via inelastic alpha-particle scattering with the Grand Raiden (GR) Spectrometer at the Research Center for Nuclear Physics (RCNP), Japan. In the deformed nuclei 146-150Nd, the ISGMR strength distributions exhibit a splitting into two components, while the nearly spherical nucleus 142Nd displays a single peak in the ISGMR strength distribution. A noteworthy achievement in this study is the first-time detection of overtones in the Isoscalar Giant Quadrupole Resonance (ISGQR) strength distributions within Nd isotopes at an excitation energy around 25 MeV obtained through Multipole Decomposition Analysis (MDA)., Comment: Accepted for publication in Physics Letters B

Published
2024
Full Text
View/download PDF

2. Search for the 6$\alpha$ condensed state in $^{24}$Mg using the $^{12}\rm{C}+{}^{12}\rm{C}$ scattering

Author

Fujikawa, Y., Kawabata, T., Adachi, S., Enyo, S., Furuno, T., Hijikata, Y., Himi, K., Hirose, K., Honda, Y., Inaba, K., Makii, H., Miyamoto, K., Murata, M., Nishio, K., Okamoto, S., Orlandi, R., Sakanashi, K., Suzaki, F., Tsuji, S., Yahiro, K., and Zenihiro, J.

Subjects
Nuclear Experiment, Nuclear Theory
Abstract

We searched for the 6$\alpha$-condensed state in $^{24}$Mg by measuring the $^{12}\rm{C}+{}^{12}\rm{C}$ scattering with the SAKRA Si detector array at $E_\rm{cm}$ = 17.5-25.0 MeV. By using the invariant-mass method for the detected 3$\alpha$ particles, the inclusive cross sections for the $^{12}\rm{C}+{}^{12}\rm{C}\to{}^{12}\rm{C}(0^+_2)+X$ and $^{12}\rm{C}(3^-_1)+X$ reactions were determined. In addition, the missing-mass spectroscopy was successfully utilized to determine the excitation energy of the residual $^{12}\rm{C}$ nucleus and the exclusive cross sections for the $^{12}\rm{C}+{}^{12}\rm{C}\to{}^{12}\rm{C}(0^+_2)+{}^{12}\rm{C}(0^+_1)$, $^{12}\rm{C}(0^+_2)+{}^{12}\rm{C}(2^+_1)$, and $^{12}\rm{C}(0^+_2)+{}^{12}\rm{C}(0^+_2)$ reactions. In both the inclusive $^{12}\rm{C}(0^+_2)+X$ channel and the exclusive $^{12}\rm{C}(0^+_2)+{}^{12}\rm{C}(0^+_1)$ channel, the cross section peaked at $E_rm{cm}$ = 19.4 MeV, which correspond to the excitation energy of $E_x$ = 33.3 MeV in $^{24}\rm{Mg}$. This 19.4-MeV state is a candidate for the 6$\alpha$-condensed state because of the agreement of the excitation energy with the theoretical value and its decay property. In the exclusive $^{12}\rm{C}(0^+_2)+{}^{12}\rm{C}(0^+_2)$ channel, a broad state was observed at $E_\rm{cm}$ = 22.5 MeV, which correspond to the excitation energy of $E_x$ = 36.4 MeV in $^{24}\rm{Mg}$. From the angular distribution of the differential cross section, the spin and parity of this 22.5-MeV state was assigned to be $4^+$. In addition, a $2^+$ state was suggested at the low-energy side of the 22.5-MeV state. Because their excitation energies are higher than the theoretical value of the 6$\alpha$-condensed state, these states might be excited states of the 6$\alpha$-condensed state such as the $2^+_2$ and $4^+_1$ states in $^{12}\rm{C}$., Comment: 8 pages, 6 figures

Published
2023
Full Text
View/download PDF

3. Validation of the $^{10}\mathrm{Be}$ Ground-State Molecular Structure Using $^{10}\mathrm{Be}(p,p\alpha)^{6}\mathrm{He}$ Triple Differential Reaction Cross-Section Measurements

Author

Li, P. J., Beaumel, D., Lee, J., Assié, M., Chen, S., Franchoo, S., Gibelin, J., Hammache, F., Harada, T., Kanada-En'yo, Y., Kubota, Y., Leblond, S., Liang, P. F., Lokotko, T., Lyu, M., Marqués, F. M., Matsuda, Y., Ogata, K., Otsu, H., Rindel, E., Stuhl, L., Suzuki, D., Togano, Y., Tomai, T., Xu, X. X., Yoshida, K., Zenihiro, J., Achouri, N. L., Aumann, T., Baba, H., Cardella, G., Ceruti, S., Stefanescu, A. I., Corsi, A., Frotscher, A., Gao, J., Gillibert, A., Inaba, K., Isobe, T., Kawabata, T., Kitamura, N., Kobayashi, T., Kondo, Y., Kurihara, A., Liu, H. N., Miki, H., Nakamura, T., Obertelli, A., Orr, N. A., Panin, V., Sasano, M., Shimada, T., Sun, Y. L., Tanaka, J., Trache, L., Tudor, D., Uesaka, T., Wang, H., Yamada, H., Yang, Z. H., and Yasuda, M.

Subjects
Nuclear Experiment, Nuclear Theory
Abstract

The cluster structure of the neutron-rich isotope $^{10}$Be has been probed via the $(p,p\alpha)$ reaction at 150 MeV/nucleon in inverse kinematics and in quasifree conditions. The populated states of $^{6}$He residues were investigated through missing mass spectroscopy. The triple differential cross-section for the ground-state transition was extracted for quasifree angle pairs ($\theta_{p}$, $\theta_{\alpha}$) and compared to distorted-wave impulse approximation reaction calculations performed in a microscopic framework using successively the Tohsaki-Horiuchi-Schuck-R\"opke product wave-function and the wave-function deduced from Antisymmetrized Molecular Dynamics calculations. The remarkable agreement between calculated and measured cross-sections in both shape and magnitude validates the molecular structure description of the $^{10}$Be ground-state, configured as an $\alpha$-$\alpha$ core with two valence neutrons occupying $\pi$-type molecular orbitals., Comment: 7 pages, 3 figures, 1 tables

Published
2023
Full Text
View/download PDF

4. Photodisintegration Cross Section of $^4$He in the Giant Dipole Resonance Energy Region

Author

Murata, M., Kawabata, T., Adachi, S., Akimune, H., Amano, S., Fujikawa, Y., Furuno, T., Inaba, K., Ishii, Y., Miyamoto, S., Tsumura, M., and Utsunomiya, H.

Subjects
Nuclear Experiment
Abstract

We simultaneously measured the $^4$He($\gamma, n$)$^3$He and $^4$He($\gamma, p$)$^3$H reactions in the energy range around the giant dipole resonance. A quasi-monoenergetic photon beam produced via the laser Compton scattering technique was irradiated on the active-target time-projection chamber filled with helium gas, and trajectories of charged decay particles emitted from $^4$He were measured. Our data suggest that the $^4$He($\gamma, n$)$^3$He and $^4$He($\gamma, p$)$^3$H cross sections peak around 26 MeV. This result contradicts the previous experimental data reported by Shima et al. but is consistent with other experimental results., Comment: 12 pages, 6 figures

Published
2023
Full Text
View/download PDF

5. Search for $\alpha$ condensed states in $^{13}$C using $\alpha$ inelastic scattering

Author

Inaba, K., Sasamoto, Y., Kawabata, T., Fujiwara, M., Funaki, Y., Hatanaka, K., Itoh, K., Itoh, M., Kawase, K., Matsubara, H., Maeda, Y., Suda, K., Sakaguchi, S., Shimizu, Y., Tamii, A., Tameshige, Y., Uchida, M., Uesaka, T., Yamada, T., and Yoshida, H. P.

Subjects
Nuclear Experiment, Nuclear Theory
Abstract

We searched for the $\alpha$ condensed state in $^{13}$C by measuring the $\alpha$ inelastic scattering at $E_{\alpha} = 388$ MeV at forward angles including 0 degrees. We performed the distorted-wave Born-approximation calculation with the single-folding potential and the multipole decomposition analysis to determine the isoscalar transition strengths in $^{13}$C. We found a bump structure around $E_x = 12.5$ MeV due to the isoscalar monopole ($IS0$) transition. A peak-fit analysis suggested that this bump consisted of several $1/2^-$ states. We propose that this bump is due to the mirror state of the 13.5 MeV-state in $^{13}$N, which dominantly decays to the $\alpha$ condensed state in $^{12}$C. It was speculated that the $1/2^-$ states around $E_x = 12.5$ MeV were candidates for the $\alpha$ condensed state, but the $3\alpha + n$ orthogonality condition model suggests that the $\alpha$ condensed state is unlikely to emerge as the negative parity states. We also found two $1/2^+$ or $3/2^+$ states at $E_x = 14.5$ and 16.1 MeV excited with the isoscalar dipole ($IS1$) strengths. We suggest that the 16.1-MeV state is a possible candidate for the $\alpha$ condensed state predicted by the cluster-model calculations on the basis of the good correspondence between the experimental and calculated level structures. However, the theoretical $IS1$ transition strength for this state is significantly smaller than the measured value. Further experimental information is strongly desired to establish the $\alpha$ condensed state in $^{13}$C., Comment: 24 pages, 12 figures, published in PTEP

Published
2021
Full Text
View/download PDF

6. Observation of Coulomb-assisted nuclear bound state of $\Xi^-$-$^{14}$N system

Author

Hayakawa, S. H., Agari, K., Ahn, J. K., Akaishi, T., Akazawa, Y., Ashikaga, S., Bassalleck, B., Bleser, S., Ekawa, H., Endo, Y., Fujikawa, Y., Fujioka, N., Fujita, M., Goto, R., Han, Y., Hasegawa, S., Hashimoto, T., Hayakawa, T., Hayata, E., Hicks, K., Hirose, E., Hirose, M., Honda, R., Hoshino, K., Hoshino, S., Hosomi, K., Hwang, S. H., Ichikawa, Y., Ichikawa, M., Imai, K., Inaba, K., Ishikawa, Y., Ito, H., Ito, K., Jung, W. S., Kanatsuki, S., Kanauchi, H., Kasagi, A., Kawai, T., Kim, M. H., Kim, S. H., Kinbara, S., Kiuchi, R., Kobayashi, H., Kobayashi, K., Koike, T., Koshikawa, A., Lee, J. Y., Ma, T. L., Matsumoto, S. Y., Minakawa, M., Miwa, K., Moe, A. T., Moon, T. J., Moritsu, M., Nagase, Y., Nakada, Y., Nakagawa, M., Nakashima, D., Nakazawa, K., Nanamura, T., Naruki, M., Nyaw, A. N. L., Ogura, Y., Ohashi, M., Oue, K., Ozawa, S., Pochodzalla, J., Ryu, S. Y., Sako, H., Sato, S., Sato, Y., Schupp, F., Shirotori, K., Soe, M. M., Soe, M. K., Sohn, J. Y., Sugimura, H., Suzuki, K. N., Takahashi, H., Takahashi, T., Takeda, T., Tamura, H., Tanida, K., Theint, A. M. M., Tint, K. T., Toyama, Y., Ukai, M., Umezaki, E., Watabe, T., Watanabe, K., Yamamoto, T. O., Yang, S. B., Yoon, C. S., Yoshida, J., Yoshimoto, M., Zhang, D. H., and Zhang, Z.

Subjects
Nuclear Experiment
Abstract

In an emulsion-counter hybrid experiment performed at J-PARC, a $\Xi^-$ absorption event was observed which decayed into twin single-$\Lambda$ hypernuclei. Kinematic calculations enabled a unique identification of the reaction process as $\Xi^{-} + ^{14}$N$\ \rightarrow\ ^{10}_\Lambda$Be + $^5_\Lambda$He. For the binding energy of the $\Xi^{-}$ hyperon in the $\Xi^-$-$^{14}$N system a value of $1.27 \pm 0.21$ MeV was deduced. The energy level of $\Xi^-$ is likely a nuclear $1p$ state which indicates a weak ${\Xi}N$-$\Lambda\Lambda$ coupling.

Published
2020
Full Text
View/download PDF

7. Candidates for the 5$\alpha$ condensed state in ${}^{20}$Ne

Author

Adachi, S., Fujikawa, Y., Kawabata, T., Akimune, H., Doi, T., Furuno, T., Harada, T., Inaba, K., Ishida, S., Itoh, M., Iwamoto, C., Kobayashi, N., Maeda, Y., Matsuda, Y., Murata, M., Okamoto, S., Sakaue, A., Sekiya, R., Tamii, A., and Tsumura, M.

Subjects
Nuclear Experiment
Abstract

We conducted the coincidence measurement of $\alpha$ particles inelastically scattered from ${}^{20}$Ne at $0^{\circ}$ and decay charged particles in order to search for the alpha-particle condensed state. We compared the measured excitation-energy spectrum and decay branching ratio with the statistical-decay-model calculations, and found that the newly observed states at $E_x$ = 23.6, 21.8, and 21.2 MeV in ${}^{20}$Ne are strongly coupled to a candidate for the 4$\alpha$ condensed state in ${}^{16}$O. This result presents the first strong evidence that these states are the candidates for the 5$\alpha$ condensed state., Comment: 6 pages, 5 figures. The part of the analysis is updated, and some discussions are added

Published
2020
Full Text
View/download PDF

8. Compressional-mode resonances in the molybdenum isotopes: Emergence of softness in open-shell nuclei near A=90

Author

Howard, K. B., Garg, U., Itoh, M., Akimune, H., Fujiwara, M., Furuno, T., Gupta, Y. K., Harakeh, M. N., Inaba, K., Ishibashi, Y., Karasudani, K., Kawabata, T., Kohda, A., Matsuda, Y., Murata, M., Nakamura, S., Okamoto, J., Ota, S., Piekarewicz, J., Sakaue, A., Senyigit, M., Tsumura, M., and Yang, Y.

Subjects
Nuclear Experiment, Nuclear Theory
Abstract

"Why are the tin isotopes soft?" has remained, for the past decade, an open problem in nuclear structure physics: models which reproduce the isoscalar giant monopole resonance (ISGMR) in the "doubly-closed shell" nuclei, $^{90}$Zr and $^{208}$Pb, overestimate the ISGMR energies of the open-shell tin and cadmium nuclei, by as much as 1 MeV. In an effort to shed some light onto this problem, we present results of detailed studies of the ISGMR in the molybdenum nuclei, with the goal of elucidating where--and how--the softness manifests itself between $^{90}$Zr and the cadmium and tin isotopes. The experiment was conducted using the $^{94,96,98,100}$Mo($\alpha,\alpha^\prime$) reaction at $E_\alpha = 386$ MeV. A comparison of the results with relativistic, self-consistent Random-Phase Approximation calculations indicates that the ISGMR response begins to show softness in the molybdenum isotopes beginning with $A=92$., Comment: Accepted for publication to Physics Letters B

Published
2020
Full Text
View/download PDF

10. Neutron quadrupole transition strength in $^{10}$C deduced from the $^{10}$C$(\alpha,\alpha')$ measurement with the MAIKo active target

Author

Furuno, T., Kawabata, T., Adachi, S., Ayyad, Y., Kanada-En'yo, Y., Fujikawa, Y., Inaba, K., Murata, M., Ong, H. J., Sferrazza, M., Takahashi, Y., Takeda, T., Tanihata, I., Tran, D. T., and Tsumura, M.

Subjects
Nuclear Experiment
Abstract

Elastic and inelastic alpha scatterings on $^{10}$C were measured using a 68-MeV/u radioactive $^{10}$C beam incident on the recently developed MAIKo active target system. The phenomenological effective $\alpha$-$N$ interaction and the point-nucleon density distribution in the ground state were determined from the elastic scattering data. The cross sections of the inelastic alpha scattering were calculated using this interaction and density distribution and were compared with the experiment to determine the neutron quadrupole transition matrix element $M_{n}$ between the ground state and the $2_{1}^{+}$ state at $E_{x} = 3.35$ MeV in $^{10}$C. The deduced neutron transition matrix element is $M_{n} = 6.9\, \pm0.7\, \mathrm{(fit)}\, \pm1.2\, \mathrm{(sys)}$ fm$^{2}$. The ratio of the neutron transition strength to proton transition strength was determined as $M_{n}/M_{p} = 1.05\, \pm0.11\, \mathrm{(fit)}\, \pm0.17\, \mathrm{(sys)}$, which indicates that the quadrupole transition between the ground state and the $2_{1}^{+}$ state in $^{10}$C is less neutron dominant compared to that in $^{16}$C., Comment: 13 pages, 10 figures, 2 tables. The title and conclusion have changed from the previous version

Published
2019
Full Text
View/download PDF

11. Observation of a Be double-Lambda hypernucleus in the J-PARC E07 experiment

Author

Ekawa, H., Agari, K., Ahn, J. K., Akaishi, T., Akazawa, Y., Ashikaga, S., Bassalleck, B., Bleser, S., Endo, Y., Fujikawa, Y., Fujioka, N., Fujita, M., Goto, R., Han, Y., Hasegawa, S., Hashimoto, T., Hayakawa, S. H., Hayakawa, T., Hayata, E., Hicks, K., Hirose, E., Hirose, M., Honda, R., Hoshino, K., Hoshino, S., Hosomi, K., Hwang, S. H., Ichikawa, Y., Ichikawa, M., Ieiri, M., Imai, K., Inaba, K., Ishikawa, Y., Iskendir, A., Ito, H., Ito, K., Jung, W. S., Kanatsuki, S., Kanauchi, H., Kasagi, A., Kawai, T., Kim, M. H., Kim, S. H., Kinbara, S., Kiuchi, R., Kobayashi, H., Kobayashi, K., Koike, T., Koshikawa, A., Lee, J. Y., Lee, J. W., Ma, T. L., Matsumoto, S. Y., Minakawa, M., Miwa, K., Moe, A. T., Moon, T. J., Moritsu, M., Nagase, Y., Nakada, Y., Nakagawa, M., Nakashima, D., Nakazawa, K., Nanamura, T., Naruki, M., Nyaw, A. N. L., Ogura, Y., Ohashi, M., Oue, K., Ozawa, S., Pochodzalla, J., Ryu, S. Y., Sako, H., Sasaki, Y., Sato, S., Sato, Y., Schupp, F., Shirotori, K., Soe, M. M., Soe, M. K., Sohn, J. Y., Sugimura, H., Suzuki, K. N., Takahashi, H., Takahashi, T., Takahashi, Y., Takeda, T., Tamura, H., Tanida, K., Theint, A. M. M., Tint, K. T., Toyama, Y., Ukai, M., Umezaki, E., Watabe, T., Watanabe, K., Yamamoto, T. O., Yang, S. B., Yoon, C. S., Yoshida, J., Yoshimoto, M., Zhang, D. H., and Zhang, Z.

Subjects
Nuclear Experiment
Abstract

A double-$\Lambda$ hypernucleus, ${}_{\Lambda\Lambda}\mathrm{Be}$, was observed by the J-PARC E07 collaboration in nuclear emulsions tagged by the $(K^{-},K^{+})$ reaction. This event was interpreted as a production and decay of $ {}_{\Lambda\Lambda}^{\;10}\mathrm{Be}$, ${}_{\Lambda\Lambda}^{\;11}\mathrm{Be}$, or ${}_{\Lambda\Lambda}^{\;12}\mathrm{Be}^{*}$ via $\Xi^{-}$ capture in ${}^{16}\mathrm{O}$. By assuming the capture in the atomic 3D state, the binding energy of two $\Lambda$ hyperons$\,$($B_{\Lambda\Lambda}$) of these double-$\Lambda$ hypernuclei are obtained to be $15.05 \pm 0.11\,\mathrm{MeV}$, $19.07 \pm 0.11\,\mathrm{MeV}$, and $13.68 \pm 0.11\,\mathrm{MeV}$, respectively. Based on the kinematic fitting, ${}_{\Lambda\Lambda}^{\;11}\mathrm{Be}$ is the most likely explanation for the observed event., Comment: 11 pages, 3 figures

Published
2018
Full Text
View/download PDF

12. Performance test of the MAIKo active target

Author

Furuno, T., Kawabata, T., Ong, H. J., Adachi, S., Ayyad, Y., Baba, T., Fujikawa, Y., Hashimoto, T., Inaba, K., Ishii, Y., Kabuki, S., Kubo, H., Matsuda, Y., Matsuoka, Y., Mizumoto, T., Morimoto, T., Murata, M., Sawano, T., Suzuki, T., Takada, A., Tanaka, J., Tanihata, I., Tanimori, T., Tran, D. T., Tsumura, M., and Watanabe, H. D.

Subjects
Physics - Instrumentation and Detectors
Abstract

A new active target named MAIKo (Mu-PIC based Active target for Inverse Kinematics$_{\circ}$) has been developed at Kyoto University and Research Center for Nuclear Physics (RCNP), Osaka University. MAIKo is suited for missing-mass spectroscopy of unstable nuclei at forward scattering angles in inverse kinematics. MAIKo consists of a time projection chamber (TPC), which incorporates a micro-pixel chamber ($\mu$-PIC) as the electron multiplication and collection system. In MAIKo, the medium gas also plays the role of a reaction target, thus allowing detection of low-energy recoil particles with high position resolution. The MAIKo TPC was commissioned with He(93%)+iso-C$_{4}$H$_{10}$(7%) and He(93%)+CO$_{2}$(7%) mixture gasses at 430 hPa. The gas gain and the angular resolution of MAIKo were evaluated with an alpha source and a $^{4}$He beam at 56 MeV. The TPC was stably operated up to 1000-kcps beam intensity. A tracking algorithm using the Hough transform method has been developed to analyze scattering events. An angular resolution of 1.3$^{\circ}$ was achieved for scattered $^{4}$He particles., Comment: 13 pages, 17 figures

Published
2018
Full Text
View/download PDF

21. Early management of adult traumatic spinal cord injury in patients with polytrauma: a consensus and clinical recommendations jointly developed by the World Society of Emergency Surgery (WSES) & the European Association of Neurosurgical Societies (EANS)

Author

Picetti, E, Demetriades, A, Catena, F, Aarabi, B, Abu-Zidan, F, Alves, O, Ansaloni, L, Armonda, R, Badenes, R, Bala, M, Balogh, Z, Barbanera, A, Bertuccio, A, Biffl, W, Bouzat, P, Buki, A, Castano-Leon, A, Cerasti, D, Citerio, G, Coccolini, F, Coimbra, R, Coniglio, C, Costa, F, De Iure, F, Depreitere, B, Fainardi, E, Fehlings, M, Gabrovsky, N, Godoy, D, Gruen, P, Gupta, D, Hawryluk, G, Helbok, R, Hossain, I, Hutchinson, P, Iaccarino, C, Inaba, K, Ivanov, M, Kaprovoy, S, Kirkpatrick, A, Klein, S, Kolias, A, Konovalov, N, Lagares, A, Lippa, L, Loza-Gomez, A, Luoto, T, Maas, A, Maciejczak, A, Maier, R, Marklund, N, Martin, M, Melloni, I, Mendoza-Lattes, S, Meyfroidt, G, Munari, M, Napolitano, L, Okonkwo, D, Otomo, Y, Papadopoulos, M, Petr, O, Peul, W, Pudkrong, A, Qasim, Z, Rasulo, F, Reizinho, C, Ringel, F, Rizoli, S, Rostami, E, Rubiano, A, Russo, E, Sarwal, A, Schwab, J, Servadei, F, Sharma, D, Sharif, S, Shiban, E, Shutter, L, Stahel, P, Taccone, F, Terpolilli, N, Thomé, C, Toth, P, Tsitsopoulos, P, Udy, A, Vaccaro, A, Varon, A, Vavilala, M, Younsi, A, Zackova, M, Zoerle, T, Robba, C, Picetti, Edoardo, Demetriades, Andreas K., Catena, Fausto, Aarabi, Bizhan, Abu-Zidan, Fikri M., Alves, Oscar L., Ansaloni, Luca, Armonda, Rocco A., Badenes, Rafael, Bala, Miklosh, Balogh, Zsolt J., Barbanera, Andrea, Bertuccio, Alessandro, Biffl, Walter L., Bouzat, Pierre, Buki, Andras, Castano-Leon, Ana Maria, Cerasti, Davide, Citerio, Giuseppe, Coccolini, Federico, Coimbra, Raul, Coniglio, Carlo, Costa, Francesco, De Iure, Federico, Depreitere, Bart, Fainardi, Enrico, Fehlings, Michael J., Gabrovsky, Nikolay, Godoy, Daniel Agustin, Gruen, Peter, Gupta, Deepak, Hawryluk, Gregory W. J., Helbok, Raimund, Hossain, Iftakher, Hutchinson, Peter J., Iaccarino, Corrado, Inaba, Kenji, Ivanov, Marcel, Kaprovoy, Stanislav, Kirkpatrick, Andrew W., Klein, Sam, Kolias, Angelos, Konovalov, Nikolay A., Lagares, Alfonso, Lippa, Laura, Loza-Gomez, Angelica, Luoto, Teemu M., Maas, Andrew I. R., Maciejczak, Andrzej, Maier, Ronald V., Marklund, Niklas, Martin, Matthew J., Melloni, Ilaria, Mendoza-Lattes, Sergio, Meyfroidt, Geert, Munari, Marina, Napolitano, Lena M., Okonkwo, David O., Otomo, Yasuhiro, Papadopoulos, Marios C., Petr, Ondra, Peul, Wilco C., Pudkrong, Aichholz K., Qasim, Zaffer, Rasulo, Frank, Reizinho, Carla, Ringel, Florian, Rizoli, Sandro, Rostami, Elham, Rubiano, Andres M., Russo, Emanuele, Sarwal, Aarti, Schwab, Jan M., Servadei, Franco, Sharma, Deepak, Sharif, Salman, Shiban, Ehab, Shutter, Lori, Stahel, Philip F., Taccone, Fabio S., Terpolilli, Nicole A., Thomé, Claudius, Toth, Peter, Tsitsopoulos, Parmenion P., Udy, Andrew, Vaccaro, Alexander R., Varon, Albert J., Vavilala, Monica S., Younsi, Alexander, Zackova, Monika, Zoerle, Tommaso, Robba, Chiara, Picetti, E, Demetriades, A, Catena, F, Aarabi, B, Abu-Zidan, F, Alves, O, Ansaloni, L, Armonda, R, Badenes, R, Bala, M, Balogh, Z, Barbanera, A, Bertuccio, A, Biffl, W, Bouzat, P, Buki, A, Castano-Leon, A, Cerasti, D, Citerio, G, Coccolini, F, Coimbra, R, Coniglio, C, Costa, F, De Iure, F, Depreitere, B, Fainardi, E, Fehlings, M, Gabrovsky, N, Godoy, D, Gruen, P, Gupta, D, Hawryluk, G, Helbok, R, Hossain, I, Hutchinson, P, Iaccarino, C, Inaba, K, Ivanov, M, Kaprovoy, S, Kirkpatrick, A, Klein, S, Kolias, A, Konovalov, N, Lagares, A, Lippa, L, Loza-Gomez, A, Luoto, T, Maas, A, Maciejczak, A, Maier, R, Marklund, N, Martin, M, Melloni, I, Mendoza-Lattes, S, Meyfroidt, G, Munari, M, Napolitano, L, Okonkwo, D, Otomo, Y, Papadopoulos, M, Petr, O, Peul, W, Pudkrong, A, Qasim, Z, Rasulo, F, Reizinho, C, Ringel, F, Rizoli, S, Rostami, E, Rubiano, A, Russo, E, Sarwal, A, Schwab, J, Servadei, F, Sharma, D, Sharif, S, Shiban, E, Shutter, L, Stahel, P, Taccone, F, Terpolilli, N, Thomé, C, Toth, P, Tsitsopoulos, P, Udy, A, Vaccaro, A, Varon, A, Vavilala, M, Younsi, A, Zackova, M, Zoerle, T, Robba, C, Picetti, Edoardo, Demetriades, Andreas K., Catena, Fausto, Aarabi, Bizhan, Abu-Zidan, Fikri M., Alves, Oscar L., Ansaloni, Luca, Armonda, Rocco A., Badenes, Rafael, Bala, Miklosh, Balogh, Zsolt J., Barbanera, Andrea, Bertuccio, Alessandro, Biffl, Walter L., Bouzat, Pierre, Buki, Andras, Castano-Leon, Ana Maria, Cerasti, Davide, Citerio, Giuseppe, Coccolini, Federico, Coimbra, Raul, Coniglio, Carlo, Costa, Francesco, De Iure, Federico, Depreitere, Bart, Fainardi, Enrico, Fehlings, Michael J., Gabrovsky, Nikolay, Godoy, Daniel Agustin, Gruen, Peter, Gupta, Deepak, Hawryluk, Gregory W. J., Helbok, Raimund, Hossain, Iftakher, Hutchinson, Peter J., Iaccarino, Corrado, Inaba, Kenji, Ivanov, Marcel, Kaprovoy, Stanislav, Kirkpatrick, Andrew W., Klein, Sam, Kolias, Angelos, Konovalov, Nikolay A., Lagares, Alfonso, Lippa, Laura, Loza-Gomez, Angelica, Luoto, Teemu M., Maas, Andrew I. R., Maciejczak, Andrzej, Maier, Ronald V., Marklund, Niklas, Martin, Matthew J., Melloni, Ilaria, Mendoza-Lattes, Sergio, Meyfroidt, Geert, Munari, Marina, Napolitano, Lena M., Okonkwo, David O., Otomo, Yasuhiro, Papadopoulos, Marios C., Petr, Ondra, Peul, Wilco C., Pudkrong, Aichholz K., Qasim, Zaffer, Rasulo, Frank, Reizinho, Carla, Ringel, Florian, Rizoli, Sandro, Rostami, Elham, Rubiano, Andres M., Russo, Emanuele, Sarwal, Aarti, Schwab, Jan M., Servadei, Franco, Sharma, Deepak, Sharif, Salman, Shiban, Ehab, Shutter, Lori, Stahel, Philip F., Taccone, Fabio S., Terpolilli, Nicole A., Thomé, Claudius, Toth, Peter, Tsitsopoulos, Parmenion P., Udy, Andrew, Vaccaro, Alexander R., Varon, Albert J., Vavilala, Monica S., Younsi, Alexander, Zackova, Monika, Zoerle, Tommaso, and Robba, Chiara

Abstract

Background: The early management of polytrauma patients with traumatic spinal cord injury (tSCI) is a major challenge. Sparse data is available to provide optimal care in this scenario and worldwide variability in clinical practice has been documented in recent studies. Methods: A multidisciplinary consensus panel of physicians selected for their established clinical and scientific expertise in the acute management of tSCI polytrauma patients with different specializations was established. The World Society of Emergency Surgery (WSES) and the European Association of Neurosurgical Societies (EANS) endorsed the consensus, and a modified Delphi approach was adopted. Results: A total of 17 statements were proposed and discussed. A consensus was reached generating 17 recommendations (16 strong and 1 weak). Conclusions: This consensus provides practical recommendations to support a clinician’s decision making in the management of tSCI polytrauma patients.

Published
2024

23. Search for the 6α condensed state in 24Mg using the 12C+12C scattering

Author

Fujikawa, Y., primary, Kawabata, T., additional, Adachi, S., additional, Enyo, S., additional, Furuno, T., additional, Hijikata, Y., additional, Himi, K., additional, Hirose, K., additional, Honda, Y., additional, Inaba, K., additional, Makii, H., additional, Miyamoto, K., additional, Murata, M., additional, Nishio, K., additional, Okamoto, S., additional, Orlandi, R., additional, Sakanashi, K., additional, Suzaki, F., additional, Tsuji, S., additional, Yahiro, K., additional, and Zenihiro, J., additional

Published
2023
Full Text
View/download PDF

24. Source control in emergency general surgery: WSES, GAIS, SIS-E, SIS-A guidelines

Author

Coccolini, F, Sartelli, M, Sawyer, R, Rasa, K, Viaggi, B, Abu-Zidan, F, Soreide, K, Hardcastle, T, Gupta, D, Bendinelli, C, Ceresoli, M, Shelat, V, Broek, R, Baiocchi, G, Moore, E, Sall, I, Podda, M, Bonavina, L, Kryvoruchko, I, Stahel, P, Inaba, K, Montravers, P, Sakakushev, B, Sganga, G, Ballestracci, P, Malbrain, M, Vincent, J, Pikoulis, M, Beka, S, Doklestic, K, Chiarugi, M, Falcone, M, Bignami, E, Reva, V, Demetrashvili, Z, Di Saverio, S, Tolonen, M, Navsaria, P, Bala, M, Balogh, Z, Litvin, A, Hecker, A, Wani, I, Fette, A, De Simone, B, Ivatury, R, Picetti, E, Khokha, V, Tan, E, Ball, C, Tascini, C, Cui, Y, Coimbra, R, Kelly, M, Martino, C, Agnoletti, V, Boermeester, M, De'Angelis, N, Chirica, M, Biffl, W, Ansaloni, L, Kluger, Y, Catena, F, Kirkpatrick, A, Coccolini F., Sartelli M., Sawyer R., Rasa K., Viaggi B., Abu-Zidan F., Soreide K., Hardcastle T., Gupta D., Bendinelli C., Ceresoli M., Shelat V. G., Broek R., Baiocchi G. L., Moore E. E., Sall I., Podda M., Bonavina L., Kryvoruchko I. A., Stahel P., Inaba K., Montravers P., Sakakushev B., Sganga G., Ballestracci P., Malbrain M. L. N. G., Vincent J. -L., Pikoulis M., Beka S. G., Doklestic K., Chiarugi M., Falcone M., Bignami E., Reva V., Demetrashvili Z., Di Saverio S., Tolonen M., Navsaria P., Bala M., Balogh Z., Litvin A., Hecker A., Wani I., Fette A., De Simone B., Ivatury R., Picetti E., Khokha V., Tan E., Ball C., Tascini C., Cui Y., Coimbra R., Kelly M., Martino C., Agnoletti V., Boermeester M. A., De'Angelis N., Chirica M., Biffl W. L., Ansaloni L., Kluger Y., Catena F., Kirkpatrick A. W., Coccolini, F, Sartelli, M, Sawyer, R, Rasa, K, Viaggi, B, Abu-Zidan, F, Soreide, K, Hardcastle, T, Gupta, D, Bendinelli, C, Ceresoli, M, Shelat, V, Broek, R, Baiocchi, G, Moore, E, Sall, I, Podda, M, Bonavina, L, Kryvoruchko, I, Stahel, P, Inaba, K, Montravers, P, Sakakushev, B, Sganga, G, Ballestracci, P, Malbrain, M, Vincent, J, Pikoulis, M, Beka, S, Doklestic, K, Chiarugi, M, Falcone, M, Bignami, E, Reva, V, Demetrashvili, Z, Di Saverio, S, Tolonen, M, Navsaria, P, Bala, M, Balogh, Z, Litvin, A, Hecker, A, Wani, I, Fette, A, De Simone, B, Ivatury, R, Picetti, E, Khokha, V, Tan, E, Ball, C, Tascini, C, Cui, Y, Coimbra, R, Kelly, M, Martino, C, Agnoletti, V, Boermeester, M, De'Angelis, N, Chirica, M, Biffl, W, Ansaloni, L, Kluger, Y, Catena, F, Kirkpatrick, A, Coccolini F., Sartelli M., Sawyer R., Rasa K., Viaggi B., Abu-Zidan F., Soreide K., Hardcastle T., Gupta D., Bendinelli C., Ceresoli M., Shelat V. G., Broek R., Baiocchi G. L., Moore E. E., Sall I., Podda M., Bonavina L., Kryvoruchko I. A., Stahel P., Inaba K., Montravers P., Sakakushev B., Sganga G., Ballestracci P., Malbrain M. L. N. G., Vincent J. -L., Pikoulis M., Beka S. G., Doklestic K., Chiarugi M., Falcone M., Bignami E., Reva V., Demetrashvili Z., Di Saverio S., Tolonen M., Navsaria P., Bala M., Balogh Z., Litvin A., Hecker A., Wani I., Fette A., De Simone B., Ivatury R., Picetti E., Khokha V., Tan E., Ball C., Tascini C., Cui Y., Coimbra R., Kelly M., Martino C., Agnoletti V., Boermeester M. A., De'Angelis N., Chirica M., Biffl W. L., Ansaloni L., Kluger Y., Catena F., and Kirkpatrick A. W.

Abstract

Intra-abdominal infections (IAI) are among the most common global healthcare challenges and they are usually precipitated by disruption to the gastrointestinal (GI) tract. Their successful management typically requires intensive resource utilization, and despite the best therapies, morbidity and mortality remain high. One of the main issues required to appropriately treat IAI that differs from the other etiologies of sepsis is the frequent requirement to provide physical source control. Fortunately, dramatic advances have been made in this aspect of treatment. Historically, source control was left to surgeons only. With new technologies non-surgical less invasive interventional procedures have been introduced. Alternatively, in addition to formal surgery open abdomen techniques have long been proposed as aiding source control in severe intra-abdominal sepsis. It is ironic that while a lack or even delay regarding source control clearly associates with death, it is a concept that remains poorly described. For example, no conclusive definition of source control technique or even adequacy has been universally accepted. Practically, source control involves a complex definition encompassing several factors including the causative event, source of infection bacteria, local bacterial flora, patient condition, and his/her eventual comorbidities. With greater understanding of the systemic pathobiology of sepsis and the profound implications of the human microbiome, adequate source control is no longer only a surgical issue but one that requires a multidisciplinary, multimodality approach. Thus, while any breach in the GI tract must be controlled, source control should also attempt to control the generation and propagation of the systemic biomediators and dysbiotic influences on the microbiome that perpetuate multi-system organ failure and death. Given these increased complexities, the present paper represents the current opinions and recommendations for future research of th

Published
2023

25. ECLAPTE: Effective Closure of LAParoTomy in Emergency-2023 World Society of Emergency Surgery guidelines for the closure of laparotomy in emergency settings

Author

Frassini, S, Cobianchi, L, Fugazzola, P, Biffl, W, Coccolini, F, Damaskos, D, Moore, E, Kluger, Y, Ceresoli, M, Coimbra, R, Davies, J, Kirkpatrick, A, Di Carlo, I, Hardcastle, T, Isik, A, Chiarugi, M, Gurusamy, K, Maier, R, Segovia Lohse, H, Jeekel, H, Boermeester, M, Abu-Zidan, F, Inaba, K, Weber, D, Augustin, G, Bonavina, L, Velmahos, G, Sartelli, M, Di Saverio, S, Ten Broek, R, Granieri, S, Dal Mas, F, Fare, C, Peverada, J, Zanghi, S, Vigano, J, Tomasoni, M, Dominioni, T, Cicuttin, E, Hecker, A, Tebala, G, Galante, J, Wani, I, Khokha, V, Sugrue, M, Scalea, T, Tan, E, Malangoni, M, Pararas, N, Podda, M, De Simone, B, Ivatury, R, Cui, Y, Kashuk, J, Peitzman, A, Kim, F, Pikoulis, E, Sganga, G, Chiara, O, Kelly, M, Marzi, I, Picetti, E, Agnoletti, V, De'Angelis, N, Campanelli, G, de Moya, M, Litvin, A, Martinez-Perez, A, Sall, I, Rizoli, S, Tomadze, G, Sakakushev, B, Stahel, P, Civil, I, Shelat, V, Costa, D, Chichom-Mefire, A, Latifi, R, Chirica, M, Amico, F, Pardhan, A, Seenarain, V, Boyapati, N, Hatz, B, Ackermann, T, Abeyasundara, S, Fenton, L, Plani, F, Sarvepalli, R, Rouhbakhshfar, O, Caleo, P, Ho-Ching Yau, V, Clement, K, Christou, E, Castillo, A, Gosal, P, Balasubramaniam, S, Hsu, J, Banphawatanarak, K, Pisano, M, Adriana, T, Michele, A, Cioffi, S, Spota, A, Catena, F, Ansaloni, L, Frassini S., Cobianchi L., Fugazzola P., Biffl W. L., Coccolini F., Damaskos D., Moore E. E., Kluger Y., Ceresoli M., Coimbra R., Davies J., Kirkpatrick A., Di Carlo I., Hardcastle T. C., Isik A., Chiarugi M., Gurusamy K., Maier R. V., Segovia Lohse H. A., Jeekel H., Boermeester M. A., Abu-Zidan F., Inaba K., Weber D. G., Augustin G., Bonavina L., Velmahos G., Sartelli M., Di Saverio S., Ten Broek R. P. G., Granieri S., Dal Mas F., Fare C. N., Peverada J., Zanghi S., Vigano J., Tomasoni M., Dominioni T., Cicuttin E., Hecker A., Tebala G. D., Galante J. M., Wani I., Khokha V., Sugrue M., Scalea T. M., Tan E., Malangoni M. A., Pararas N., Podda M., De Simone B., Ivatury R., Cui Y., Kashuk J., Peitzman A., Kim F., Pikoulis E., Sganga G., Chiara O., Kelly M. D., Marzi I., Picetti E., Agnoletti V., De'Angelis N., Campanelli G., de Moya M., Litvin A., Martinez-Perez A., Sall I., Rizoli S., Tomadze G., Sakakushev B., Stahel P. F., Civil I., Shelat V., Costa D., Chichom-Mefire A., Latifi R., Chirica M., Amico F., Pardhan A., Seenarain V., Boyapati N., Hatz B., Ackermann T., Abeyasundara S., Fenton L., Plani F., Sarvepalli R., Rouhbakhshfar O., Caleo P., Ho-Ching Yau V., Clement K., Christou E., Castillo A. M. G., Gosal P. K. S., Balasubramaniam S., Hsu J., Banphawatanarak K., Pisano M., Adriana T., Michele A., Cioffi S. P. B., Spota A., Catena F., Ansaloni L., Frassini, S, Cobianchi, L, Fugazzola, P, Biffl, W, Coccolini, F, Damaskos, D, Moore, E, Kluger, Y, Ceresoli, M, Coimbra, R, Davies, J, Kirkpatrick, A, Di Carlo, I, Hardcastle, T, Isik, A, Chiarugi, M, Gurusamy, K, Maier, R, Segovia Lohse, H, Jeekel, H, Boermeester, M, Abu-Zidan, F, Inaba, K, Weber, D, Augustin, G, Bonavina, L, Velmahos, G, Sartelli, M, Di Saverio, S, Ten Broek, R, Granieri, S, Dal Mas, F, Fare, C, Peverada, J, Zanghi, S, Vigano, J, Tomasoni, M, Dominioni, T, Cicuttin, E, Hecker, A, Tebala, G, Galante, J, Wani, I, Khokha, V, Sugrue, M, Scalea, T, Tan, E, Malangoni, M, Pararas, N, Podda, M, De Simone, B, Ivatury, R, Cui, Y, Kashuk, J, Peitzman, A, Kim, F, Pikoulis, E, Sganga, G, Chiara, O, Kelly, M, Marzi, I, Picetti, E, Agnoletti, V, De'Angelis, N, Campanelli, G, de Moya, M, Litvin, A, Martinez-Perez, A, Sall, I, Rizoli, S, Tomadze, G, Sakakushev, B, Stahel, P, Civil, I, Shelat, V, Costa, D, Chichom-Mefire, A, Latifi, R, Chirica, M, Amico, F, Pardhan, A, Seenarain, V, Boyapati, N, Hatz, B, Ackermann, T, Abeyasundara, S, Fenton, L, Plani, F, Sarvepalli, R, Rouhbakhshfar, O, Caleo, P, Ho-Ching Yau, V, Clement, K, Christou, E, Castillo, A, Gosal, P, Balasubramaniam, S, Hsu, J, Banphawatanarak, K, Pisano, M, Adriana, T, Michele, A, Cioffi, S, Spota, A, Catena, F, Ansaloni, L, Frassini S., Cobianchi L., Fugazzola P., Biffl W. L., Coccolini F., Damaskos D., Moore E. E., Kluger Y., Ceresoli M., Coimbra R., Davies J., Kirkpatrick A., Di Carlo I., Hardcastle T. C., Isik A., Chiarugi M., Gurusamy K., Maier R. V., Segovia Lohse H. A., Jeekel H., Boermeester M. A., Abu-Zidan F., Inaba K., Weber D. G., Augustin G., Bonavina L., Velmahos G., Sartelli M., Di Saverio S., Ten Broek R. P. G., Granieri S., Dal Mas F., Fare C. N., Peverada J., Zanghi S., Vigano J., Tomasoni M., Dominioni T., Cicuttin E., Hecker A., Tebala G. D., Galante J. M., Wani I., Khokha V., Sugrue M., Scalea T. M., Tan E., Malangoni M. A., Pararas N., Podda M., De Simone B., Ivatury R., Cui Y., Kashuk J., Peitzman A., Kim F., Pikoulis E., Sganga G., Chiara O., Kelly M. D., Marzi I., Picetti E., Agnoletti V., De'Angelis N., Campanelli G., de Moya M., Litvin A., Martinez-Perez A., Sall I., Rizoli S., Tomadze G., Sakakushev B., Stahel P. F., Civil I., Shelat V., Costa D., Chichom-Mefire A., Latifi R., Chirica M., Amico F., Pardhan A., Seenarain V., Boyapati N., Hatz B., Ackermann T., Abeyasundara S., Fenton L., Plani F., Sarvepalli R., Rouhbakhshfar O., Caleo P., Ho-Ching Yau V., Clement K., Christou E., Castillo A. M. G., Gosal P. K. S., Balasubramaniam S., Hsu J., Banphawatanarak K., Pisano M., Adriana T., Michele A., Cioffi S. P. B., Spota A., Catena F., and Ansaloni L.

Abstract

Laparotomy incisions provide easy and rapid access to the peritoneal cavity in case of emergency surgery. Incisional hernia (IH) is a late manifestation of the failure of abdominal wall closure and represents frequent complication of any abdominal incision: IHs can cause pain and discomfort to the patients but also clinical serious sequelae like bowel obstruction, incarceration, strangulation, and necessity of reoperation. Previous guidelines and indications in the literature consider elective settings and evidence about laparotomy closure in emergency settings is lacking. This paper aims to present the World Society of Emergency Surgery (WSES) project called ECLAPTE (Effective Closure of LAParoTomy in Emergency): the final manuscript includes guidelines on the closure of emergency laparotomy.

Published
2023

26. The new timing in acute care surgery (new TACS) classification: a WSES Delphi consensus study

Author

De Simone, B, Kluger, Y, Moore, E, Sartelli, M, Abu-Zidan, F, Coccolini, F, Ansaloni, L, Tebala, G, Di Saverio, S, Di Carlo, I, Sakakushev, B, Bonavina, L, Sugrue, M, Galante, J, Ivatury, R, Picetti, E, Chirica, M, Wani, I, Bala, M, Sall, I, Kirkpatrick, A, Shelat, V, Pikoulis, E, Leppäniemi, A, Tan, E, Broek, R, Gurmu Beka, S, Litvin, A, Chouillard, E, Coimbra, R, Cui, Y, De’ Angelis, N, Sganga, G, Stahel, P, Agnoletti, V, Rampini, A, Damaskos, D, Carcoforo, P, Biffl, W, Hecker, A, Di Salomone, S, Balogh, Z, Beka, S, Velmahos, G, Ceresoli, M, Chiara, O, Leppaniemi, A, Marzi, I, Inaba, K, Khokha, V, Reva, V, Khan, M, Toro, A, de’ Angelis, N, Malangoni, M, Scozzafava, E, Civil, I, Maier, R, Weber, D, Chiarugi, M, Soreide, K, Testini, M, Bravi, F, Catena, F, De Simone B., Kluger Y., Moore E. E., Sartelli M., Abu-Zidan F. M., Coccolini F., Ansaloni L., Tebala G. D., Di Saverio S., Di Carlo I., Sakakushev B. E., Bonavina L., Sugrue M., Galante J. M., Ivatury R., Picetti E., Chirica M., Wani I., Bala M., Sall I., Kirkpatrick A. W., Shelat V. G., Pikoulis E., Leppäniemi A., Tan E., Broek R. P. G. t., Gurmu Beka S., Litvin A., Chouillard E., Coimbra R., Cui Y., De’ Angelis N., Sganga G., Stahel P. F., Agnoletti V., Rampini A., Shelat V., Damaskos D., Carcoforo P., Biffl W. L., Hecker A., Kirkpatrick A., Di Salomone S., Balogh Z., Beka S. G., Broek R. T., Velmahos G., Sakakushev B., Ceresoli M., Chiara O., Stahel P., Leppaniemi A., Marzi I., Inaba K., Khokha V., Reva V., Khan M., Toro A., de’ Angelis N., Malangoni M., Scozzafava E., Civil I., Maier R., Weber D., Chiarugi M., Soreide K., Testini M., Bravi F., Maier R. V., Catena F., De Simone, B, Kluger, Y, Moore, E, Sartelli, M, Abu-Zidan, F, Coccolini, F, Ansaloni, L, Tebala, G, Di Saverio, S, Di Carlo, I, Sakakushev, B, Bonavina, L, Sugrue, M, Galante, J, Ivatury, R, Picetti, E, Chirica, M, Wani, I, Bala, M, Sall, I, Kirkpatrick, A, Shelat, V, Pikoulis, E, Leppäniemi, A, Tan, E, Broek, R, Gurmu Beka, S, Litvin, A, Chouillard, E, Coimbra, R, Cui, Y, De’ Angelis, N, Sganga, G, Stahel, P, Agnoletti, V, Rampini, A, Damaskos, D, Carcoforo, P, Biffl, W, Hecker, A, Di Salomone, S, Balogh, Z, Beka, S, Velmahos, G, Ceresoli, M, Chiara, O, Leppaniemi, A, Marzi, I, Inaba, K, Khokha, V, Reva, V, Khan, M, Toro, A, de’ Angelis, N, Malangoni, M, Scozzafava, E, Civil, I, Maier, R, Weber, D, Chiarugi, M, Soreide, K, Testini, M, Bravi, F, Catena, F, De Simone B., Kluger Y., Moore E. E., Sartelli M., Abu-Zidan F. M., Coccolini F., Ansaloni L., Tebala G. D., Di Saverio S., Di Carlo I., Sakakushev B. E., Bonavina L., Sugrue M., Galante J. M., Ivatury R., Picetti E., Chirica M., Wani I., Bala M., Sall I., Kirkpatrick A. W., Shelat V. G., Pikoulis E., Leppäniemi A., Tan E., Broek R. P. G. t., Gurmu Beka S., Litvin A., Chouillard E., Coimbra R., Cui Y., De’ Angelis N., Sganga G., Stahel P. F., Agnoletti V., Rampini A., Shelat V., Damaskos D., Carcoforo P., Biffl W. L., Hecker A., Kirkpatrick A., Di Salomone S., Balogh Z., Beka S. G., Broek R. T., Velmahos G., Sakakushev B., Ceresoli M., Chiara O., Stahel P., Leppaniemi A., Marzi I., Inaba K., Khokha V., Reva V., Khan M., Toro A., de’ Angelis N., Malangoni M., Scozzafava E., Civil I., Maier R., Weber D., Chiarugi M., Soreide K., Testini M., Bravi F., Maier R. V., and Catena F.

Abstract

Background: Timely access to the operating room for emergency general surgery (EGS) indications remains a challenge across the globe, largely driven by operating room availability and staffing constraints. The “timing in acute care surgery” (TACS) classification was previously published to introduce a new tool to triage the timely and appropriate access of EGS patients to the operating room. However, the clinical and operational effectiveness of the TACS classification has not been investigated in subsequent validation studies. This study aimed to improve the TACS classification and provide further consensus around the appropriate use of the new TACS classification through a standardized Delphi approach with international experts. Methods: This is a validation study of the new TACS by a selected international panel of experts using the Delphi method. The TACS questionnaire was designed as a web-based survey. The consensus agreement level was established to be ≥ 75%. The collective consensus agreement was defined as the sum of the percentage of the highest Likert scale levels (4–5) out of all participants. Surgical emergency diseases and correlated clinical scenarios were defined for each of the proposed classes. Subsequent rounds were carried out until a definitive level of consensus was reached. Frequencies and percentages were calculated to determine the degree of agreement for each surgical disease. Results: Four polling rounds were carried out. The new TACS classification provides 6 colour-code classes correlated to a precise timing to surgery, defined scenarios and surgical condition. The WHITE colour-code class was introduced to rapidly (within a week) reschedule cancelled or postponed surgical procedures. Haemodynamic stability is the main tool to stratify patients for immediate surgery or not in the presence of sepsis/septic shock. Fifty-one surgical diseases were included in the different colour-code classes of priority. Conclusion: The new TACS classificat

Published
2023

27. Antitumor activity and induction of TP53-dependent apoptosis toward ovarian clear cell adenocarcinoma by the dual PI3K/mTOR inhibitor DS-7423

Author

McCormick, Frank, Kashiyama, T, Oda, K, Ikeda, Y, Shiose, Y, Hirota, Y, Inaba, K, Makii, C, Kurikawa, R, Miyasaka, A, and Koso, T

Abstract

DS-7423, a novel, small-molecule dual inhibitor of phosphatidylinositol-3- kinase (PI3K) and mammalian target of rapamycin (mTOR), is currently in phase I clinical trials for solid tumors. Although DS-7423 potently inhibits PI3Kα (IC50 = 15.6 nM) and mTOR

Published
2014

28. Validation of the Be10 Ground-State Molecular Structure Using Be10(p,pα)He6 Triple Differential Reaction Cross-Section Measurements

Author

Li, P. J., primary, Beaumel, D., additional, Lee, J., additional, Assié, M., additional, Chen, S., additional, Franchoo, S., additional, Gibelin, J., additional, Hammache, F., additional, Harada, T., additional, Kanada-En’yo, Y., additional, Kubota, Y., additional, Leblond, S., additional, Liang, P. F., additional, Lokotko, T., additional, Lyu, M., additional, Marqués, F. M., additional, Matsuda, Y., additional, Ogata, K., additional, Otsu, H., additional, Rindel, E., additional, Stuhl, L., additional, Suzuki, D., additional, Togano, Y., additional, Tomai, T., additional, Xu, X. X., additional, Yoshida, K., additional, Zenihiro, J., additional, Achouri, N. L., additional, Aumann, T., additional, Baba, H., additional, Cardella, G., additional, Ceruti, S., additional, Stefanescu, A. I., additional, Corsi, A., additional, Frotscher, A., additional, Gao, J., additional, Gillibert, A., additional, Inaba, K., additional, Isobe, T., additional, Kawabata, T., additional, Kitamura, N., additional, Kobayashi, T., additional, Kondo, Y., additional, Kurihara, A., additional, Liu, H. N., additional, Miki, H., additional, Nakamura, T., additional, Obertelli, A., additional, Orr, N. A., additional, Panin, V., additional, Sasano, M., additional, Shimada, T., additional, Sun, Y. L., additional, Tanaka, J., additional, Trache, L., additional, Tudor, D., additional, Uesaka, T., additional, Wang, H., additional, Yamada, H., additional, Yang, Z. H., additional, and Yasuda, M., additional

Published
2023
Full Text
View/download PDF

30. Zero-temperature Phase Diagram of Two Dimensional Hubbard Model

Author

Inaba, K., Koga, A., Suga, S., and Kawakami, N.

Subjects
Condensed Matter - Strongly Correlated Electrons
Abstract

We investigate the two-dimensional Hubbard model on the triangular lattice with anisotropic hopping integrals at half filling. By means of a self-energy functional approach, we discuss how stable the non-magnetic state is against magnetically ordered states in the system. We present the zero-temperature phase diagram, where the normal metallic state competes with magnetically ordered states with $(\pi, \pi)$ and $(2\pi/3, 2\pi/3)$ structures. It is shown that a non-magnetic Mott insulating state is not realized as the ground state, in the present framework, but as a meta-stable state near the magnetically ordered phase with $(2\pi/3, 2\pi/3)$ structure., Comment: 4 pages, 4 figures

Published
2008
Full Text
View/download PDF

31. Mott transitions in two-orbital Hubbard systems

Author

Koga, A., Inaba, K., and Kawakami, N.

Subjects
Condensed Matter - Strongly Correlated Electrons
Abstract

We investigate the Mott transitions in two-orbital Hubbard systems. Applying the dynamical mean field theory and the self-energy functional approach, we discuss the stability of itinerant quasi-particle states in each band. It is shown that separate Mott transitions occur at different Coulomb interaction strengths in general. On the other hand, if some special conditions are satisfied for the interactions, spin and orbital fluctuations are equally enhanced at low temperatures, resulting in a single Mott transition. The phase diagrams are obtained at zero and finite temperatures. We also address the effect of the hybridization between two orbitals, which induces the Kondo-like heavy fermion states in the intermediate orbital-selective Mott phase., Comment: 21 Pages, 17 Figures, to appear in Progress of Theoretical Physics (YKIS2004 Proceedings)

Published
2005
Full Text
View/download PDF

34. The new timing in acute care surgery (new TACS) classification: a WSES Delphi consensus study

Author

De Simone B., Kluger Y., Moore E. E., Sartelli M., Abu-Zidan F. M., Coccolini F., Ansaloni L., Tebala G. D., Di Saverio S., Di Carlo I., Sakakushev B. E., Bonavina L., Sugrue M., Galante J. M., Ivatury R., Picetti E., Chirica M., Wani I., Bala M., Sall I., Kirkpatrick A. W., Shelat V. G., Pikoulis E., Leppäniemi A., Tan E., Broek R. P. G. t., Gurmu Beka S., Litvin A., Chouillard E., Coimbra R., Cui Y., De’ Angelis N., Sganga G., Stahel P. F., Agnoletti V., Rampini A., Shelat V., Damaskos D., Carcoforo P., Biffl W. L., Hecker A., Kirkpatrick A., Di Salomone S., Balogh Z., Beka S. G., Broek R. T., Velmahos G., Sakakushev B., Ceresoli M., Chiara O., Stahel P., Leppaniemi A., Marzi I., Inaba K., Khokha V., Reva V., Khan M., Toro A., de’ Angelis N., Malangoni M., Scozzafava E., Civil I., Maier R., Weber D., Chiarugi M., Soreide K., Testini M., Bravi F., Maier R. V., Catena F., De Simone, B, Kluger, Y, Moore, E, Sartelli, M, Abu-Zidan, F, Coccolini, F, Ansaloni, L, Tebala, G, Di Saverio, S, Di Carlo, I, Sakakushev, B, Bonavina, L, Sugrue, M, Galante, J, Ivatury, R, Picetti, E, Chirica, M, Wani, I, Bala, M, Sall, I, Kirkpatrick, A, Shelat, V, Pikoulis, E, Leppäniemi, A, Tan, E, Broek, R, Gurmu Beka, S, Litvin, A, Chouillard, E, Coimbra, R, Cui, Y, De’ Angelis, N, Sganga, G, Stahel, P, Agnoletti, V, Rampini, A, Damaskos, D, Carcoforo, P, Biffl, W, Hecker, A, Di Salomone, S, Balogh, Z, Beka, S, Velmahos, G, Ceresoli, M, Chiara, O, Leppaniemi, A, Marzi, I, Inaba, K, Khokha, V, Reva, V, Khan, M, Toro, A, de’ Angelis, N, Malangoni, M, Scozzafava, E, Civil, I, Maier, R, Weber, D, Chiarugi, M, Soreide, K, Testini, M, Bravi, F, and Catena, F

Subjects
Healthcare system, Delay in surgery, Operating room management, Delphi method, Emergency surgery, Priority, Time to surgery, Timing in acute care surgery (TACS), Triage, Classification
Abstract

Background: Timely access to the operating room for emergency general surgery (EGS) indications remains a challenge across the globe, largely driven by operating room availability and staffing constraints. The “timing in acute care surgery” (TACS) classification was previously published to introduce a new tool to triage the timely and appropriate access of EGS patients to the operating room. However, the clinical and operational effectiveness of the TACS classification has not been investigated in subsequent validation studies. This study aimed to improve the TACS classification and provide further consensus around the appropriate use of the new TACS classification through a standardized Delphi approach with international experts. Methods: This is a validation study of the new TACS by a selected international panel of experts using the Delphi method. The TACS questionnaire was designed as a web-based survey. The consensus agreement level was established to be ≥ 75%. The collective consensus agreement was defined as the sum of the percentage of the highest Likert scale levels (4–5) out of all participants. Surgical emergency diseases and correlated clinical scenarios were defined for each of the proposed classes. Subsequent rounds were carried out until a definitive level of consensus was reached. Frequencies and percentages were calculated to determine the degree of agreement for each surgical disease. Results: Four polling rounds were carried out. The new TACS classification provides 6 colour-code classes correlated to a precise timing to surgery, defined scenarios and surgical condition. The WHITE colour-code class was introduced to rapidly (within a week) reschedule cancelled or postponed surgical procedures. Haemodynamic stability is the main tool to stratify patients for immediate surgery or not in the presence of sepsis/septic shock. Fifty-one surgical diseases were included in the different colour-code classes of priority. Conclusion: The new TACS classification is a comprehensive, simple, clear and reproducible triage system which can be used to assess the severity of the patient and the surgical disease, to reduce the time to access to the operating room, and to manage the emergency surgical patients within a “safe” timeframe. By including well-defined surgical diseases in the different colour-code classes of priority, validated through a Delphi consensus, the new TACS improves communication among surgeons, between surgeons and anaesthesiologists and decreases conflicts and waste and waiting time in accessing the operating room for emergency surgical patients.

Published
2023

35. Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery

Author

Bala, M, Catena, F, Kashuk, J, De Simone, B, Gomes, C, Weber, D, Sartelli, M, Coccolini, F, Kluger, Y, Abu-Zidan, F, Picetti, E, Ansaloni, L, Augustin, G, Biffl, W, Ceresoli, M, Chiara, O, Chiarugi, M, Coimbra, R, Cui, Y, Damaskos, D, Di Saverio, S, Galante, J, Khokha, V, Kirkpatrick, A, Inaba, K, Leppaniemi, A, Litvin, A, Peitzman, A, Shelat, V, Sugrue, M, Tolonen, M, Rizoli, S, Sall, I, Beka, S, Di Carlo, I, Ten Broek, R, Mircea, C, Tebala, G, Pisano, M, van Goor, H, Maier, R, Jeekel, H, Civil, I, Hecker, A, Tan, E, Soreide, K, Lee, M, Wani, I, Bonavina, L, Malangoni, M, Koike, K, Velmahos, G, Fraga, G, Fette, A, De'Angelis, N, Balogh, Z, Scalea, T, Sganga, G, Kelly, M, Khan, J, Stahel, P, Moore, E, Bala M., Catena F., Kashuk J., De Simone B., Gomes C. A., Weber D., Sartelli M., Coccolini F., Kluger Y., Abu-Zidan F. M., Picetti E., Ansaloni L., Augustin G., Biffl W. L., Ceresoli M., Chiara O., Chiarugi M., Coimbra R., Cui Y., Damaskos D., Di Saverio S., Galante J. M., Khokha V., Kirkpatrick A. W., Inaba K., Leppaniemi A., Litvin A., Peitzman A. B., Shelat V. G., Sugrue M., Tolonen M., Rizoli S., Sall I., Beka S. G., Di Carlo I., Ten Broek R., Mircea C., Tebala G., Pisano M., van Goor H., Maier R. V., Jeekel H., Civil I., Hecker A., Tan E., Soreide K., Lee M. J., Wani I., Bonavina L., Malangoni M. A., Koike K., Velmahos G. C., Fraga G. P., Fette A., de'Angelis N., Balogh Z. J., Scalea T. M., Sganga G., Kelly M. D., Khan J., Stahel P. F., Moore E. E., Bala, M, Catena, F, Kashuk, J, De Simone, B, Gomes, C, Weber, D, Sartelli, M, Coccolini, F, Kluger, Y, Abu-Zidan, F, Picetti, E, Ansaloni, L, Augustin, G, Biffl, W, Ceresoli, M, Chiara, O, Chiarugi, M, Coimbra, R, Cui, Y, Damaskos, D, Di Saverio, S, Galante, J, Khokha, V, Kirkpatrick, A, Inaba, K, Leppaniemi, A, Litvin, A, Peitzman, A, Shelat, V, Sugrue, M, Tolonen, M, Rizoli, S, Sall, I, Beka, S, Di Carlo, I, Ten Broek, R, Mircea, C, Tebala, G, Pisano, M, van Goor, H, Maier, R, Jeekel, H, Civil, I, Hecker, A, Tan, E, Soreide, K, Lee, M, Wani, I, Bonavina, L, Malangoni, M, Koike, K, Velmahos, G, Fraga, G, Fette, A, De'Angelis, N, Balogh, Z, Scalea, T, Sganga, G, Kelly, M, Khan, J, Stahel, P, Moore, E, Bala M., Catena F., Kashuk J., De Simone B., Gomes C. A., Weber D., Sartelli M., Coccolini F., Kluger Y., Abu-Zidan F. M., Picetti E., Ansaloni L., Augustin G., Biffl W. L., Ceresoli M., Chiara O., Chiarugi M., Coimbra R., Cui Y., Damaskos D., Di Saverio S., Galante J. M., Khokha V., Kirkpatrick A. W., Inaba K., Leppaniemi A., Litvin A., Peitzman A. B., Shelat V. G., Sugrue M., Tolonen M., Rizoli S., Sall I., Beka S. G., Di Carlo I., Ten Broek R., Mircea C., Tebala G., Pisano M., van Goor H., Maier R. V., Jeekel H., Civil I., Hecker A., Tan E., Soreide K., Lee M. J., Wani I., Bonavina L., Malangoni M. A., Koike K., Velmahos G. C., Fraga G. P., Fette A., de'Angelis N., Balogh Z. J., Scalea T. M., Sganga G., Kelly M. D., Khan J., Stahel P. F., and Moore E. E.

Abstract

Acute mesenteric ischemia (AMI) is a group of diseases characterized by an interruption of the blood supply to varying portions of the intestine, leading to ischemia and secondary inflammatory changes. If untreated, this process may progress to life-threatening intestinal necrosis. The incidence is low, estimated at 0.09–0.2% of all acute surgical admissions, but increases with age. Although the entity is an uncommon cause of abdominal pain, diligence is required because if untreated, mortality remains in the range of 50%. Early diagnosis and timely surgical intervention are the cornerstones of modern treatment to reduce the high mortality associated with this entity. The advent of endovascular approaches in parallel with modern imaging techniques is evolving and provides new treatment options. Lastly, a focused multidisciplinary approach based on early diagnosis and individualized treatment is essential. Thus, we believe that updated guidelines from World Society of Emergency Surgery are warranted, in order to provide the most recent and practical recommendations for diagnosis and treatment of AMI.

Published
2022

36. Follow-up strategies for patients with splenic trauma managed non-operatively: the 2022 World Society of Emergency Surgery consensus document

Author

Podda, M, De Simone, B, Ceresoli, M, Virdis, F, Favi, F, Wiik Larsen, J, Coccolini, F, Sartelli, M, Pararas, N, Beka, S, Bonavina, L, Bova, R, Pisanu, A, Abu-Zidan, F, Balogh, Z, Chiara, O, Wani, I, Stahel, P, Di Saverio, S, Scalea, T, Soreide, K, Sakakushev, B, Amico, F, Martino, C, Hecker, A, De'Angelis, N, Chirica, M, Galante, J, Kirkpatrick, A, Pikoulis, E, Kluger, Y, Bensard, D, Ansaloni, L, Fraga, G, Civil, I, Tebala, G, Di Carlo, I, Cui, Y, Coimbra, R, Agnoletti, V, Sall, I, Tan, E, Picetti, E, Litvin, A, Damaskos, D, Inaba, K, Leung, J, Maier, R, Biffl, W, Leppaniemi, A, Moore, E, Gurusamy, K, Catena, F, Podda M., De Simone B., Ceresoli M., Virdis F., Favi F., Wiik Larsen J., Coccolini F., Sartelli M., Pararas N., Beka S. G., Bonavina L., Bova R., Pisanu A., Abu-Zidan F., Balogh Z., Chiara O., Wani I., Stahel P., Di Saverio S., Scalea T., Soreide K., Sakakushev B., Amico F., Martino C., Hecker A., de'Angelis N., Chirica M., Galante J., Kirkpatrick A., Pikoulis E., Kluger Y., Bensard D., Ansaloni L., Fraga G., Civil I., Tebala G. D., Di Carlo I., Cui Y., Coimbra R., Agnoletti V., Sall I., Tan E., Picetti E., Litvin A., Damaskos D., Inaba K., Leung J., Maier R., Biffl W., Leppaniemi A., Moore E., Gurusamy K., Catena F., Podda, M, De Simone, B, Ceresoli, M, Virdis, F, Favi, F, Wiik Larsen, J, Coccolini, F, Sartelli, M, Pararas, N, Beka, S, Bonavina, L, Bova, R, Pisanu, A, Abu-Zidan, F, Balogh, Z, Chiara, O, Wani, I, Stahel, P, Di Saverio, S, Scalea, T, Soreide, K, Sakakushev, B, Amico, F, Martino, C, Hecker, A, De'Angelis, N, Chirica, M, Galante, J, Kirkpatrick, A, Pikoulis, E, Kluger, Y, Bensard, D, Ansaloni, L, Fraga, G, Civil, I, Tebala, G, Di Carlo, I, Cui, Y, Coimbra, R, Agnoletti, V, Sall, I, Tan, E, Picetti, E, Litvin, A, Damaskos, D, Inaba, K, Leung, J, Maier, R, Biffl, W, Leppaniemi, A, Moore, E, Gurusamy, K, Catena, F, Podda M., De Simone B., Ceresoli M., Virdis F., Favi F., Wiik Larsen J., Coccolini F., Sartelli M., Pararas N., Beka S. G., Bonavina L., Bova R., Pisanu A., Abu-Zidan F., Balogh Z., Chiara O., Wani I., Stahel P., Di Saverio S., Scalea T., Soreide K., Sakakushev B., Amico F., Martino C., Hecker A., de'Angelis N., Chirica M., Galante J., Kirkpatrick A., Pikoulis E., Kluger Y., Bensard D., Ansaloni L., Fraga G., Civil I., Tebala G. D., Di Carlo I., Cui Y., Coimbra R., Agnoletti V., Sall I., Tan E., Picetti E., Litvin A., Damaskos D., Inaba K., Leung J., Maier R., Biffl W., Leppaniemi A., Moore E., Gurusamy K., and Catena F.

Abstract

Background: In 2017, the World Society of Emergency Surgery published its guidelines for the management of adult and pediatric patients with splenic trauma. Several issues regarding the follow-up of patients with splenic injuries treated with NOM remained unsolved. Methods: Using a modified Delphi method, we sought to explore ongoing areas of controversy in the NOM of splenic trauma and reach a consensus among a group of 48 international experts from five continents (Africa, Europe, Asia, Oceania, America) concerning optimal follow-up strategies in patients with splenic injuries treated with NOM. Results: Consensus was reached on eleven clinical research questions and 28 recommendations with an agreement rate ≥ 80%. Mobilization after 24 h in low-grade splenic trauma patients (WSES Class I, AAST Grades I–II) was suggested, while in patients with high-grade splenic injuries (WSES Classes II–III, AAST Grades III–V), if no other contraindications to early mobilization exist, safe mobilization of the patient when three successive hemoglobins 8 h apart after the first are within 10% of each other was considered safe according to the panel. The panel suggests adult patients to be admitted to hospital for 1 day (for low-grade splenic injuries—WSES Class I, AAST Grades I–II) to 3 days (for high-grade splenic injuries—WSES Classes II–III, AAST Grades III–V), with those with high-grade injuries requiring admission to a monitored setting. In the absence of specific complications, the panel suggests DVT and VTE prophylaxis with LMWH to be started within 48–72 h from hospital admission. The panel suggests splenic artery embolization (SAE) as the first-line intervention in patients with hemodynamic stability and arterial blush on CT scan, irrespective of injury grade. Regarding patients with WSES Class II blunt splenic injuries (AAST Grade III) without contrast extravasation, a low threshold for SAE has been suggested in the presence of risk factors for NOM failure. The panel als

Published
2022

37. Minimally invasive surgery in emergency surgery: a WSES survey

Author

Ceresoli, M, Pisano, M, Abu-Zidan, F, Allievi, N, Gurusamy, K, Biffl, W, Tebala, G, Catena, F, Ansaloni, L, Sartelli, M, Kluger, Y, Baiocchi, G, Fette, A, Hecker, A, Litvin, A, Forgione, A, Leppaniemi, A, De Simone, B, Sakakushev, B, Palmatier, C, Bendinelli, C, Damascos, D, Picetti, E, Tan, E, Poiasina, E, Pikoulis, E, Cicuttin, E, Moore, E, Velmahos, G, Fraga, G, Van Goor, H, Civil, I, Wani, I, Di Carlo, I, Galante, J, Soreide, K, Degrate, L, Zorcolo, L, De Moya, M, Braga, M, Cereda, M, Sugrue, M, Chirica, M, De Angelis, N, Stahel, P, Ivatury, R, Ten Broek, R, Di Saverio, S, Beka, S, Magnone, S, Cui, Y, Balogh, Z, Kelly, M, Inaba, K, Coccolini, F, Ceresoli M., Pisano M., Abu-Zidan F., Allievi N., Gurusamy K., Biffl W. L., Tebala G. D., Catena F., Ansaloni L., Sartelli M., Kluger Y., Baiocchi G., Fette A., Hecker A., Litvin A., Forgione A., Leppaniemi A., De Simone B., Sakakushev B., Palmatier C. R., Bendinelli C., Damascos D., Picetti E., Tan E., Poiasina E., Pikoulis E., Cicuttin E., Moore E. E., Velmahos G., Fraga G., Van Goor H., Civil I., Wani I., Di Carlo I., Galante J., Soreide K., Degrate L., Zorcolo L., De Moya M., Braga M., Cereda M., Sugrue M., Chirica M., De Angelis N., Stahel P. F., Ivatury R., Ten Broek R., Di Saverio S., Beka S. G., Magnone S., Cui Y., Balogh Z. J., Kelly M. D., Inaba K., Coccolini F., Ceresoli, M, Pisano, M, Abu-Zidan, F, Allievi, N, Gurusamy, K, Biffl, W, Tebala, G, Catena, F, Ansaloni, L, Sartelli, M, Kluger, Y, Baiocchi, G, Fette, A, Hecker, A, Litvin, A, Forgione, A, Leppaniemi, A, De Simone, B, Sakakushev, B, Palmatier, C, Bendinelli, C, Damascos, D, Picetti, E, Tan, E, Poiasina, E, Pikoulis, E, Cicuttin, E, Moore, E, Velmahos, G, Fraga, G, Van Goor, H, Civil, I, Wani, I, Di Carlo, I, Galante, J, Soreide, K, Degrate, L, Zorcolo, L, De Moya, M, Braga, M, Cereda, M, Sugrue, M, Chirica, M, De Angelis, N, Stahel, P, Ivatury, R, Ten Broek, R, Di Saverio, S, Beka, S, Magnone, S, Cui, Y, Balogh, Z, Kelly, M, Inaba, K, Coccolini, F, Ceresoli M., Pisano M., Abu-Zidan F., Allievi N., Gurusamy K., Biffl W. L., Tebala G. D., Catena F., Ansaloni L., Sartelli M., Kluger Y., Baiocchi G., Fette A., Hecker A., Litvin A., Forgione A., Leppaniemi A., De Simone B., Sakakushev B., Palmatier C. R., Bendinelli C., Damascos D., Picetti E., Tan E., Poiasina E., Pikoulis E., Cicuttin E., Moore E. E., Velmahos G., Fraga G., Van Goor H., Civil I., Wani I., Di Carlo I., Galante J., Soreide K., Degrate L., Zorcolo L., De Moya M., Braga M., Cereda M., Sugrue M., Chirica M., De Angelis N., Stahel P. F., Ivatury R., Ten Broek R., Di Saverio S., Beka S. G., Magnone S., Cui Y., Balogh Z. J., Kelly M. D., Inaba K., and Coccolini F.

Abstract

Background: The diffusion of minimally invasive surgery in emergency surgery still represents a developing challenge. Evidence about the use of minimally invasive surgery shows its feasibility and safety; however, the diffusion of these techniques is still poor. The aims of the present survey were to explore the diffusion and variations in the use of minimally invasive surgery among surgeons in the emergency setting. Methods: This is a web-based survey administered to all the WSES members investigating the diffusion of minimally invasive surgery in emergency. The survey investigated personal characteristics of participants, hospital characteristics, personal confidence in the use of minimally invasive surgery in emergency, limitations in the use of it and limitations to prosecute minimally invasive surgery in emergency surgery. Characteristics related to the use of minimally invasive surgery were studied with a multivariate ordinal regression. Results: The survey collected a total of 415 answers; 42.2% of participants declared a working experience > 15 years and 69.4% of responders worked in tertiary level center or academic hospital. In primary emergencies, only 28,7% of participants declared the use of laparoscopy in more than 50% of times. Personal confidence with minimally invasive techniques was the highest for appendectomy and cholecystectomy. At multivariate ordinal regression, a longer professional experience, the use of laparoscopy in major elective surgery and bariatric surgery expertise were related to a higher use of laparoscopy in emergency surgery. Conclusions: The survey shows that minimally invasive techniques in emergency surgery are still underutilized. Greater focus should be placed on the development of dedicated training in laparoscopy among emergency surgeons.

Published
2022

38. WSES/GAIS/WSIS/SIS-E/AAST global clinical pathways for patients with skin and soft tissue infections

Author

Sartelli, M, Coccolini, F, Kluger, Y, Agastra, E, Abu-Zidan, F, Abbas, A, Ansaloni, L, Adesunkanmi, A, Augustin, G, Bala, M, Baraket, O, Biffl, W, Ceresoli, M, Cerutti, E, Chiara, O, Cicuttin, E, Chiarugi, M, Coimbra, R, Corsi, D, Cortese, F, Cui, Y, Damaskos, D, De'Angelis, N, Delibegovic, S, Demetrashvili, Z, De Simone, B, de Jonge, S, Di Bella, S, Di Saverio, S, Duane, T, Fugazzola, P, Galante, J, Ghnnam, W, Gkiokas, G, Gomes, C, Griffiths, E, Hardcastle, T, Hecker, A, Herzog, T, Karamarkovic, A, Khokha, V, Kim, P, Kim, J, Kirkpatrick, A, Kong, V, Koshy, R, Inaba, K, Isik, A, Ivatury, R, Labricciosa, F, Lee, Y, Leppaniemi, A, Litvin, A, Luppi, D, Maier, R, Marinis, A, Marwah, S, Mesina, C, Moore, E, Moore, F, Negoi, I, Olaoye, I, Ordonez, C, Ouadii, M, Peitzman, A, Perrone, G, Pintar, T, Pipitone, G, Podda, M, Rasa, K, Ribeiro, J, Rodrigues, G, Rubio-Perez, I, Sall, I, Sato, N, Sawyer, R, Shelat, V, Sugrue, M, Tarasconi, A, Tolonen, M, Viaggi, B, Celotti, A, Casella, C, Pagani, L, Dhingra, S, Baiocchi, G, Catena, F, Sartelli M., Coccolini F., Kluger Y., Agastra E., Abu-Zidan F. M., Abbas A. E. S., Ansaloni L., Adesunkanmi A. K., Augustin G., Bala M., Baraket O., Biffl W. L., Ceresoli M., Cerutti E., Chiara O., Cicuttin E., Chiarugi M., Coimbra R., Corsi D., Cortese F., Cui Y., Damaskos D., de'Angelis N., Delibegovic S., Demetrashvili Z., De Simone B., de Jonge S. W., Di Bella S., Di Saverio S., Duane T. M., Fugazzola P., Galante J. M., Ghnnam W., Gkiokas G., Gomes C. A., Griffiths E. A., Hardcastle T. C., Hecker A., Herzog T., Karamarkovic A., Khokha V., Kim P. K., Kim J. I., Kirkpatrick A. W., Kong V., Koshy R. M., Inaba K., Isik A., Ivatury R., Labricciosa F. M., Lee Y. Y., Leppaniemi A., Litvin A., Luppi D., Maier R. V., Marinis A., Marwah S., Mesina C., Moore E. E., Moore F. A., Negoi I., Olaoye I., Ordonez C. A., Ouadii M., Peitzman A. B., Perrone G., Pintar T., Pipitone G., Podda M., Rasa K., Ribeiro J., Rodrigues G., Rubio-Perez I., Sall I., Sato N., Sawyer R. G., Shelat V. G., Sugrue M., Tarasconi A., Tolonen M., Viaggi B., Celotti A., Casella C., Pagani L., Dhingra S., Baiocchi G. L., Catena F., Sartelli, M, Coccolini, F, Kluger, Y, Agastra, E, Abu-Zidan, F, Abbas, A, Ansaloni, L, Adesunkanmi, A, Augustin, G, Bala, M, Baraket, O, Biffl, W, Ceresoli, M, Cerutti, E, Chiara, O, Cicuttin, E, Chiarugi, M, Coimbra, R, Corsi, D, Cortese, F, Cui, Y, Damaskos, D, De'Angelis, N, Delibegovic, S, Demetrashvili, Z, De Simone, B, de Jonge, S, Di Bella, S, Di Saverio, S, Duane, T, Fugazzola, P, Galante, J, Ghnnam, W, Gkiokas, G, Gomes, C, Griffiths, E, Hardcastle, T, Hecker, A, Herzog, T, Karamarkovic, A, Khokha, V, Kim, P, Kim, J, Kirkpatrick, A, Kong, V, Koshy, R, Inaba, K, Isik, A, Ivatury, R, Labricciosa, F, Lee, Y, Leppaniemi, A, Litvin, A, Luppi, D, Maier, R, Marinis, A, Marwah, S, Mesina, C, Moore, E, Moore, F, Negoi, I, Olaoye, I, Ordonez, C, Ouadii, M, Peitzman, A, Perrone, G, Pintar, T, Pipitone, G, Podda, M, Rasa, K, Ribeiro, J, Rodrigues, G, Rubio-Perez, I, Sall, I, Sato, N, Sawyer, R, Shelat, V, Sugrue, M, Tarasconi, A, Tolonen, M, Viaggi, B, Celotti, A, Casella, C, Pagani, L, Dhingra, S, Baiocchi, G, Catena, F, Sartelli M., Coccolini F., Kluger Y., Agastra E., Abu-Zidan F. M., Abbas A. E. S., Ansaloni L., Adesunkanmi A. K., Augustin G., Bala M., Baraket O., Biffl W. L., Ceresoli M., Cerutti E., Chiara O., Cicuttin E., Chiarugi M., Coimbra R., Corsi D., Cortese F., Cui Y., Damaskos D., de'Angelis N., Delibegovic S., Demetrashvili Z., De Simone B., de Jonge S. W., Di Bella S., Di Saverio S., Duane T. M., Fugazzola P., Galante J. M., Ghnnam W., Gkiokas G., Gomes C. A., Griffiths E. A., Hardcastle T. C., Hecker A., Herzog T., Karamarkovic A., Khokha V., Kim P. K., Kim J. I., Kirkpatrick A. W., Kong V., Koshy R. M., Inaba K., Isik A., Ivatury R., Labricciosa F. M., Lee Y. Y., Leppaniemi A., Litvin A., Luppi D., Maier R. V., Marinis A., Marwah S., Mesina C., Moore E. E., Moore F. A., Negoi I., Olaoye I., Ordonez C. A., Ouadii M., Peitzman A. B., Perrone G., Pintar T., Pipitone G., Podda M., Rasa K., Ribeiro J., Rodrigues G., Rubio-Perez I., Sall I., Sato N., Sawyer R. G., Shelat V. G., Sugrue M., Tarasconi A., Tolonen M., Viaggi B., Celotti A., Casella C., Pagani L., Dhingra S., Baiocchi G. L., and Catena F.

Abstract

Skin and soft-tissue infections (SSTIs) encompass a variety of pathological conditions that involve the skin and underlying subcutaneous tissue, fascia, or muscle, ranging from simple superficial infections to severe necrotizing infections. Together, the World Society of Emergency Surgery, the Global Alliance for Infections in Surgery, the Surgical Infection Society-Europe, The World Surgical Infection Society, and the American Association for the Surgery of Trauma have jointly completed an international multi-society document to promote global standards of care in SSTIs guiding clinicians by describing reasonable approaches to the management of SSTIs. An extensive non-systematic review was conducted using the PubMed and MEDLINE databases, limited to the English language. The resulting evidence was shared by an international task force with different clinical backgrounds.

Published
2022

40. ECLAPTE: Effective Closure of LAParoTomy in Emergency-2023 World Society of Emergency Surgery guidelines for the closure of laparotomy in emergency settings.

Author

Frassini, S., Cobianchi, L., Fugazzola, P., Biffl, W.L., Coccolini, F., Damaskos, D., Moore, E.E., Kluger, Y., Ceresoli, M., Coimbra, R., Davies, J., Kirkpatrick, A., Carlo, I. Di, Hardcastle, T.C., Isik, A., Chiarugi, M., Gurusamy, K., Maier, R.V., Segovia Lohse, H.A., Jeekel, H., Boermeester, M.A., Abu-Zidan, F., Inaba, K., Weber, D.G., Augustin, G., Bonavina, L., Velmahos, G., Sartelli, M., Saverio, S. Di, Broek, R.P.G ten, Granieri, S., Mas, F. Dal, Farè, C.N., Peverada, J., Zanghì, S., Viganò, J., Tomasoni, M., Dominioni, T., Cicuttin, E., Hecker, A., Tebala, G.D., Galante, J.M., Wani, I., Khokha, V., Sugrue, M., Scalea, T.M., Tan, E.C.T.H., Malangoni, M.A., Pararas, N., Podda, M., Simone, B. De, Ivatury, R., Cui, Y., Kashuk, J., Peitzman, A., Kim, F., Pikoulis, E., Sganga, G., Chiara, O., Kelly, M.D., Marzi, I., Picetti, E., Agnoletti, V., De'Angelis, N., Campanelli, G., Moya, M. de, Litvin, A., Martínez-Pérez, A., Sall, I., Rizoli, S., Tomadze, G., Sakakushev, B., Stahel, P.F., Civil, I., Shelat, V., Costa, D., Chichom-Mefire, A., Latifi, R., Chirica, M., Amico, F., Pardhan, A., Seenarain, V., Boyapati, N., Hatz, B., Ackermann, T., Abeyasundara, S., Fenton, L., Plani, F., Sarvepalli, R., Rouhbakhshfar, O., Caleo, P., Ho-Ching Yau, V., Clement, K., Christou, E., Castillo, A.M.G., Gosal, P.K.S., Balasubramaniam, S., Hsu, J., Banphawatanarak, K., Pisano, M., Adriana, T., Michele, A., Cioffi, S.P.B., Spota, A., Catena, F., Ansaloni, L., Frassini, S., Cobianchi, L., Fugazzola, P., Biffl, W.L., Coccolini, F., Damaskos, D., Moore, E.E., Kluger, Y., Ceresoli, M., Coimbra, R., Davies, J., Kirkpatrick, A., Carlo, I. Di, Hardcastle, T.C., Isik, A., Chiarugi, M., Gurusamy, K., Maier, R.V., Segovia Lohse, H.A., Jeekel, H., Boermeester, M.A., Abu-Zidan, F., Inaba, K., Weber, D.G., Augustin, G., Bonavina, L., Velmahos, G., Sartelli, M., Saverio, S. Di, Broek, R.P.G ten, Granieri, S., Mas, F. Dal, Farè, C.N., Peverada, J., Zanghì, S., Viganò, J., Tomasoni, M., Dominioni, T., Cicuttin, E., Hecker, A., Tebala, G.D., Galante, J.M., Wani, I., Khokha, V., Sugrue, M., Scalea, T.M., Tan, E.C.T.H., Malangoni, M.A., Pararas, N., Podda, M., Simone, B. De, Ivatury, R., Cui, Y., Kashuk, J., Peitzman, A., Kim, F., Pikoulis, E., Sganga, G., Chiara, O., Kelly, M.D., Marzi, I., Picetti, E., Agnoletti, V., De'Angelis, N., Campanelli, G., Moya, M. de, Litvin, A., Martínez-Pérez, A., Sall, I., Rizoli, S., Tomadze, G., Sakakushev, B., Stahel, P.F., Civil, I., Shelat, V., Costa, D., Chichom-Mefire, A., Latifi, R., Chirica, M., Amico, F., Pardhan, A., Seenarain, V., Boyapati, N., Hatz, B., Ackermann, T., Abeyasundara, S., Fenton, L., Plani, F., Sarvepalli, R., Rouhbakhshfar, O., Caleo, P., Ho-Ching Yau, V., Clement, K., Christou, E., Castillo, A.M.G., Gosal, P.K.S., Balasubramaniam, S., Hsu, J., Banphawatanarak, K., Pisano, M., Adriana, T., Michele, A., Cioffi, S.P.B., Spota, A., Catena, F., and Ansaloni, L.

Abstract

Contains fulltext : 296003.pdf (Publisher’s version ) (Open Access), Laparotomy incisions provide easy and rapid access to the peritoneal cavity in case of emergency surgery. Incisional hernia (IH) is a late manifestation of the failure of abdominal wall closure and represents frequent complication of any abdominal incision: IHs can cause pain and discomfort to the patients but also clinical serious sequelae like bowel obstruction, incarceration, strangulation, and necessity of reoperation. Previous guidelines and indications in the literature consider elective settings and evidence about laparotomy closure in emergency settings is lacking. This paper aims to present the World Society of Emergency Surgery (WSES) project called ECLAPTE (Effective Closure of LAParoTomy in Emergency): the final manuscript includes guidelines on the closure of emergency laparotomy.

Published
2023

41. Source control in emergency general surgery: WSES, GAIS, SIS-E, SIS-A guidelines.

Author

Coccolini, F., Sartelli, M., Sawyer, R., Rasa, K., Viaggi, B., Abu-Zidan, F., Soreide, K., Hardcastle, T., Gupta, D., Bendinelli, C., Ceresoli, M., Shelat, V.G., Broek, R.P. ten, Baiocchi, G.L., Moore, E.E., Sall, I., Podda, M., Bonavina, L., Kryvoruchko, I.A., Stahel, P., Inaba, K., Montravers, P., Sakakushev, B., Sganga, G., Ballestracci, P., Malbrain, M.L.N.G., Vincent, J.L., Pikoulis, M., Beka, S.G., Doklestic, K., Chiarugi, M., Falcone, M., Bignami, E., Reva, V., Demetrashvili, Z., Saverio, S. Di, Tolonen, M., Navsaria, P., Bala, M., Balogh, Z., Litvin, A., Hecker, A., Wani, I., Fette, A., Simone, B. De, Ivatury, R., Picetti, E., Khokha, V., Tan, E.C.T.H., Ball, C., Tascini, C., Cui, Y., Coimbra, R., Kelly, M., Martino, C., Agnoletti, V., Boermeester, M.A., De'Angelis, N., Chirica, M., Biffl, W.L., Ansaloni, L., Kluger, Y., Catena, F., Kirkpatrick, A.W., Coccolini, F., Sartelli, M., Sawyer, R., Rasa, K., Viaggi, B., Abu-Zidan, F., Soreide, K., Hardcastle, T., Gupta, D., Bendinelli, C., Ceresoli, M., Shelat, V.G., Broek, R.P. ten, Baiocchi, G.L., Moore, E.E., Sall, I., Podda, M., Bonavina, L., Kryvoruchko, I.A., Stahel, P., Inaba, K., Montravers, P., Sakakushev, B., Sganga, G., Ballestracci, P., Malbrain, M.L.N.G., Vincent, J.L., Pikoulis, M., Beka, S.G., Doklestic, K., Chiarugi, M., Falcone, M., Bignami, E., Reva, V., Demetrashvili, Z., Saverio, S. Di, Tolonen, M., Navsaria, P., Bala, M., Balogh, Z., Litvin, A., Hecker, A., Wani, I., Fette, A., Simone, B. De, Ivatury, R., Picetti, E., Khokha, V., Tan, E.C.T.H., Ball, C., Tascini, C., Cui, Y., Coimbra, R., Kelly, M., Martino, C., Agnoletti, V., Boermeester, M.A., De'Angelis, N., Chirica, M., Biffl, W.L., Ansaloni, L., Kluger, Y., Catena, F., and Kirkpatrick, A.W.

Abstract

Item does not contain fulltext, Intra-abdominal infections (IAI) are among the most common global healthcare challenges and they are usually precipitated by disruption to the gastrointestinal (GI) tract. Their successful management typically requires intensive resource utilization, and despite the best therapies, morbidity and mortality remain high. One of the main issues required to appropriately treat IAI that differs from the other etiologies of sepsis is the frequent requirement to provide physical source control. Fortunately, dramatic advances have been made in this aspect of treatment. Historically, source control was left to surgeons only. With new technologies non-surgical less invasive interventional procedures have been introduced. Alternatively, in addition to formal surgery open abdomen techniques have long been proposed as aiding source control in severe intra-abdominal sepsis. It is ironic that while a lack or even delay regarding source control clearly associates with death, it is a concept that remains poorly described. For example, no conclusive definition of source control technique or even adequacy has been universally accepted. Practically, source control involves a complex definition encompassing several factors including the causative event, source of infection bacteria, local bacterial flora, patient condition, and his/her eventual comorbidities. With greater understanding of the systemic pathobiology of sepsis and the profound implications of the human microbiome, adequate source control is no longer only a surgical issue but one that requires a multidisciplinary, multimodality approach. Thus, while any breach in the GI tract must be controlled, source control should also attempt to control the generation and propagation of the systemic biomediators and dysbiotic influences on the microbiome that perpetuate multi-system organ failure and death. Given these increased complexities, the present paper represents the current opinions and recommendations for future research of th

Published
2023

45. E2 Pi of SERCA2b

Author

Zhang, Y., primary, Watanabe, S., additional, Tsutsumi, A., additional, and Inaba, K., additional

Published
2022
Full Text
View/download PDF

49. Photodisintegration cross sectionof ⁴He in the giant dipole resonance energy region

Author

Murata, M., Kawabata, T., Adachi, S., Akimune, H., Amano, S., Fujikawa, Y., Furuno, T., Inaba, K., Ishii, Y., Miyamoto, S., Tsumura, M., and Utsunomiya, H.

Abstract

Murata M., Kawabata T., Adachi S., et al. Photodisintegration cross sectionof ⁴He in the giant dipole resonance energy region. Physical Review C 107, 21 (2023); https://doi.org/10.1103/PhysRevC.107.064317., We have performed for the first time the simultaneous measurement of the two-body and three-body photodisintegration cross sections of ⁴He in the energy range from 21.8 to 29.8 MeV using monoenergetic pulsed photons and a 4π time projection chamber containing ⁴He gas as an active target in an event-by-event mode. The photon beam was produced via the Compton backscattering of laser photons with high-energy electrons. The ⁴He(γ,p)³H and ⁴He(γ,n)³He cross sections were found to increase monotonically with energy up to 29.8 MeV, in contrast to the result of a recent theoretical calculation based on the Lorentz integral transform method that predicted a pronounced peak at around 26–27 MeV. The energy dependence of the obtained ⁴He(γ,n)³He cross section up to 26.5 MeV is marginally consistent with a Faddeev-type calculation predicting a flat pattern of the excitation function. The cross section ratio of ⁴4He(γ,p)³H to ⁴He(γ,n)³He is found to be consistent with the expected value for charge symmetry of the strong interaction within the experimental uncertainty in the measured energy range. The present results for the total and two-body cross sections of the photodisintegration of ⁴He are compared to previous experimental data and recent theoretical calculations.

Published
2023

50. Open Abdomen and Fluid Instillation in the Septic Abdomen: Results from the IROA Study

Author

Coccolini F., Gubbiotti F., Ceresoli M., Tartaglia D., Fugazzola P., Ansaloni L., Sartelli M., Kluger Y., Kirkpatrick A., Amico F., Catena F., Chiarugi M., Montori G., Salvetti F., Negoi I., Zese M., Occhionorelli S., Shlyapnikov S., Sugrue M., Demetrashvili Z., Dondossola D., Ioannidis O., Novelli G., Nacoti M., Khor D., Inaba K., Demetriades D., Kaussen T., Jusoh A. C., Ghannam W., Sakakushev B., Guetta O., Dogjani A., Costa S., Singh S., Damaskos D., Isik A., Yuan K. -C., Trotta F., Rausei S., Martinez-Perez A., Bellanova G., Fonseca V. C., Hernandez F., Marinis A., Fernandes W., Quiodettis M., Bala M., Vereczkei A., Curado R., Fraga G. P., Pereira B. M., Gachabayov M., Chagerben G. P., Arellano M. L., Ozyazici S., Costa G., Tezcaner T., Porta M., Li Y., Karateke F., Manatakis D., Mariani F., Lora F., Sahderov I., Atanasov B., Zegarra S., Fattori L., Ivatury R., Xiao J., Ben-Ishay O., Lippi A., Improta M., Zharikov A., Dubuisson V., Coccolini, F, Gubbiotti, F, Ceresoli, M, Tartaglia, D, Fugazzola, P, Ansaloni, L, Sartelli, M, Kluger, Y, Kirkpatrick, A, Amico, F, Catena, F, Chiarugi, M, Montori, G, Salvetti, F, Negoi, I, Zese, M, Occhionorelli, S, Shlyapnikov, S, Sugrue, M, Demetrashvili, Z, Dondossola, D, Ioannidis, O, Novelli, G, Nacoti, M, Khor, D, Inaba, K, Demetriades, D, Kaussen, T, Jusoh, A, Ghannam, W, Sakakushev, B, Guetta, O, Dogjani, A, Costa, S, Singh, S, Damaskos, D, Isik, A, Yuan, K, Trotta, F, Rausei, S, Martinez-Perez, A, Bellanova, G, Fonseca, V, Hernandez, F, Marinis, A, Fernandes, W, Quiodettis, M, Bala, M, Vereczkei, A, Curado, R, Fraga, G, Pereira, B, Gachabayov, M, Chagerben, G, Arellano, M, Ozyazici, S, Costa, G, Tezcaner, T, Porta, M, Li, Y, Karateke, F, Manatakis, D, Mariani, F, Lora, F, Sahderov, I, Atanasov, B, Zegarra, S, Fattori, L, Ivatury, R, Xiao, J, Ben-Ishay, O, Lippi, A, Improta, M, Zharikov, A, and Dubuisson, V

Subjects
Adult, Male, medicine.medical_specialty, Original Scientific Report, Fistula, medicine.medical_treatment, open abdomen, Peritonitis, 030230 surgery, NO, 03 medical and health sciences, 0302 clinical medicine, Sepsis, peritoneal resuscitation, Negative-pressure wound therapy, Abdomen, medicine, Humans, Surgical Wound Infection, Prospective Studies, fascial closure, peritoneal resuscitation, management, therapy, fascial closure, Digestive System Surgical Procedures, Aged, therapy, business.industry, Peritoneal fluid, Abdominal Cavity, Abdominal Wound Closure Techniques, Middle Aged, medicine.disease, Surgery, Cardiac surgery, Treatment Outcome, medicine.anatomical_structure, Cardiothoracic surgery, 030220 oncology & carcinogenesis, fluid instillation, Fluid Therapy, Female, business, Negative-Pressure Wound Therapy, management, Abdominal surgery
Abstract

Background Open abdomen (OA) is a surgical option that can be used in patients with severe peritonitis. Few evidences exist to recommend the use of intraperitoneal fluid instillation associated with OA in managing septic abdomen. Materials and methods A prospective analysis of adult patients enrolled in the International Register of Open Abdomen (trial registration: NCT02382770) was performed. Results A total of 387 patients were enrolled in two groups: 84 with peritoneal fluid instillation (FI) and 303 without (NFI). The groups were homogeneous for baseline characteristics. Overall complications were 92.9% in FI and 86.3% in NFI (p = 0.106). Complications during OA were 72.6% in FI and 59.9% in NFI (p = 0.034). Complications after definitive closure were 70.8% in FI and 61.1% in NFI (p = 0.133). Entero-atmospheric fistula was 13.1% in FI and 12% in NFI (p = 0.828). Fascial closure was 78.6% in FI and 63.7% in NFI (p = 0.02). Analysis of FI in negative pressure wound therapy (NPWT) showed: Overall morbidity in NPWT was 94% and in non-NPWT 91.2% (p = 0.622) and morbidity during OA was 68% and 79.4% (p = 0.25), respectively. Definitive fascial closure in NPWT was 87.8% and 96.8% in non-NPWT (p = 0.173). Overall mortality was 40% in NPWT and 29.4% in non-NPWT (p = 0.32) and morality during OA period was 18% and 8.8% (p = 0.238), respectively. Conclusion We found intraperitoneal fluid instillation during open abdomen in peritonitic patients to increase the complication rate during the open abdomen period, with no impact on mortality, entero-atmospheric fistula rate and opening time. Fascial closure rate is increased by instillation. Fluid instillation is feasible even when associated with nonnegative pressure temporary abdominal closure techniques.

Published
2020

Catalog

Books, media, physical & digital resources
See catalog results