Search

This article describes the way compliments and compliment responses are executed in Kunming Chinese, a Mandarin dialect spoken in Kunming, China. By looking at data collected through DCT questionnaires and natural observations, the author examines the semantic formulas used in forming compliments and compliment responses and the syntactic patterns of compliments in the two types of data. It is found that explicit compliments are the most common form of complimenting in the dialect. Implicit compliments, on the other hand, are much rarer and tend to occur by themselves. Syntactically, over 90% of the compliments fall into one of 4 syntactic structures paid through the third person/impersonal or second person perspectives. In replying to a compliment, speakers of Kunming Chinese are found to be drifting away from the tradition of rejecting compliments outright. They are more willing to accept compliments now although often indirectly. A quarter of the time, in real life situations, they just smile away a compliment they receive. While the DCT data and natural data are similar in the use of a majority of the semantic formulas, some differences are also found between the two types of data. Some methodological and cross-cultural implications are discussed at the end of the article. Key words: Kunming Chinese, descriptive study, compliment event, DCT data, natural data

BACKGROUND: Adjuvant chemotherapy (AC) is recommended since 2004 for patients with a completely resected non-small cell lung cancer (NSCLC). Indeed, several randomized clinical trials have demonstrated an improved survival for patients treated with adjuvant cisplatin-based regimen than surgery alone. In these large clinical trials, patients were well selected and fit to receive AC. As the benefit of AC was estimated at 5.4% of 5-year overall survival (OS), it seems important to evaluate AC use in a less selected population. In particular, elderly patients were underrepresented in large randomized clinical trials. Furthermore, other confounding factors might limit AC efficacy in real-life practice such as the delay of chemotherapy initiation following lung surgery or the number of AC cycles received. Therefore, the aim of this systematic review is to summarize the state of the literature on AC use in current clinical practice. METHODS: A systematic assessment of literature articles and reviews on AC use in real-life practice was performed by searching in several relevant database including Medline, Google Scholar and Cochrane Library following PICOS (i.e., Population, Intervention, Comparison, Outcomes, Study design) eligibility criteria and PRISMA guidelines. Among the 1,957 results obtained with the request formulated on these research database, 56 relevant articles on AC use in non-trial setting were selected and included in the results section. RESULTS: This systematic literature review highlights the lack of literature on AC use in real-life practice as most of these studies were retrospective. Interestingly, a delayed AC—mostly due to postoperative complications—was better than surgery alone. Furthermore, AC was less purposed to elderly patients, despite retrospective studies outlined that this therapeutic option could be benefit in this specific population as for younger patients. In real-life practice, AC was also often incomplete due to adverse events, but dose reduction or omission was not always associated with an inferior survival. In non-trial setting, number of AC cycles delivered, dose reduction or omission is quite similar to randomized clinical trials. DISCUSSION: Nowadays, AC is part of the therapeutic strategy used in completely resected NSCLC. In a population of less selected patients, this systematic literature review shows that AC can be used safely and efficiently, especially in elderly patients. As well, delayed AC seems effective. Finally, the place of immunotherapy and targeted therapies have to be precised in the future as well as biomarkers to better select patients that would response to chemotherapy.

The article describes the main characteristics of some age groups known as Generations X, Y, Z. It’s main aim consists of analyzing these generations’ characteristics in relation to the labour market. Also, on the basis of these characteristics, we set out the most efficient strategies of how to engage members of Generation Y and Z in active learning and what leadership and management they wish to find at their jobs. Digital natives, both Generation Y and Generation Z members want dynamic jobs, preferring professional autonomy and need constant growth. The information they get has to be applicable in real life, trainers have to be mentors and guides and teaching-learning methods have to combine technologies and interactive style. Managers should be their models, inspirational people, they should implement a free and flexible management style, be daily close to employees, always give feedback and create technological and collaborative working spaces.

Join operations of data sets play a crucial role in obtaining the relations of massive data in real life. Joining two data sets with MapReduce requires a proper design of the Map and Reduce stages for different scenarios. The factors affecting MapReduce join efficiency include the density of the data sets and data transmission over clusters like Hadoop. This study aims to improve the efficiency of MapReduce join algorithms on Hadoop by leveraging Shannon entropy to measure the information changes of data sets being joined in different MapReduce stages. To reduce the uncertainty of data sets in joins through the network, a novel MapReduce join algorithm with dynamic partition strategies called dynamic partition join (DPJ) is proposed. Leveraging the changes of entropy in the partitions of data sets during the Map and Reduce stages revises the logical partitions by changing the original input of the reduce tasks in the MapReduce jobs. Experimental results indicate that the entropy-based measures can measure entropy changes of join operations. Moreover, the DPJ variant methods achieved lower entropy compared with the existing joins, thereby increasing the feasibility of MapReduce join operations for different scenarios on Hadoop.

Patients and health workers were at high risk of infection during the Sars-Cov-2 pandemic lockdown. For this reason, other medical and clinical approaches such as Telemedicine were necessary. Despite Telemedicine was born before COVID-19, the pandemic was the opportunity to accelerate a process already underway for at least a decade and to blow all the barriers away. Our aim is to describe the experience of Telemedicine during and immediately after the first lockdown to assure the follow-up in a 'virtual' outpatient clinic dedicated to Rheumatic and Musculoskeletal Diseases (RMDs) and to give an overview of Telemedicine in the rheumatology field. We retrospectively evaluated the patient flow to our rheumatology division from March to September 2020 and, in accordance with local restrictions, three periods were selected. In the 1st period, 96.96% of the outpatient clinic cases were shifted to Telemedicine; these decreased to 52.45% in the 2nd period, while the 3rd period was characterized by the return of the patients at the clinic (97.6%). Diagnostic procedures were postponed during the 1st period, reduced drastically during the 2nd and performed regularly during the third period. Intravenous infusions were maintained as much as possible during the three periods, to assure therapeutic continuity. Shifting stable patients to Telemedicine has the potential to allow continuity of care, while reducing the risk of contagion during a pandemic. In the next future, the integration of Telemedicine as standard of care for specific clinical applications might assure assistance for RMDs patients also in non-pandemic conditions.

In early 2020, the unforeseen COVID-19 has brought the art world to its knees, particularly the contemporary art scene needs viewers and feedback to survive. Artists require new channels connecting them with their audiences, while artists’ work needs to be seen and appreciated by the public to sustain its value. In the face of social distancing restrictions and limited visitors, however, many international exhibitions are forced to cancel or postponed. With less to no patronage, will the global pandemic bring the end of the art world? As the global pandemic has forced most social and cultural events moving online, the art biennials are no exception. This article examines the art biennial, the Olympics of the art world, to rediscover the meaning of ‘art’ before and after COVID-19. Integrating virtual presentation and digital campaign between the Taipei Biennial and the Shanghai Biennale, the first running art biennials across the Taiwan Strait, this article analyses and presents the art world’s potential shifts in the post-pandemic future.

Background: Little is known about pathological Internet use (PIU) and online risky behaviors among elementary school children. We aimed to investigate the prevalence and factors associated with PIU and online risky behaviors. Methods: A school-based cross-sectional study was conducted in Toyama, Japan in 2018. The study included 13,413 children in the 4th–6th grades (mean, 10.5 years old) from 110 elementary schools (61.1% of elementary schools in Toyama). We assessed PIU using Young’s Diagnostic Questionnaire (YDQ) and risky behaviors. Poisson regression analysis was conducted. Results: Totally, 13,092 children returned questionnaires (response rate 97.6%). The prevalence of PIU was 4.2% and that of each risky behavior was as follows: 21.6% for spending money online, 6.6% for uploading personal movies, 5.2% for interpersonal issues, and 2.4% for having met strangers. PIU was significantly associated with boys (prevalence ratio [PR] 1.26; 95% confidence interval [CI], 1.04–1.52), skipping breakfast (PR 1.43; 95% CI, 1.14–1.79), Internet time (for 2∼3 h, PR 3.49; 95% CI, 2.63–4.65; for 3∼4 h, PR 4.45; 95% CI, 3.27–6.06; and for ≥4 h, PR 8.25; 95% CI, 6.45–10.55), physical inactivity (PR 2.63; 95% CI, 2.00–3.47), late bedtime (PR 1.86; 95% CI, 1.45–2.39 for ≥11 p.m.), no rules at home (PR 1.22; 95% CI, 1.01–1.46), no child-parent interaction (PR 1.37; 95% CI, 1.06–1.77), and no close friends in real life (PR 1.69; 95% CI, 1.30–2.19). Conclusions: PIU and risky behaviors were not rare among the elementary school children. Besides unhealthy lifestyles, social and family environments were associated with PIU. Having child-parent interaction and helping children develop close friendships in real life are effective deterrents to PIU.

Healthcare professionals often need to make clinical decisions that carry profound ethical implications. As such, they require a tool that will make decision-making intuitive. While the discussion about the principles that should guide clinical ethics has been going on for over two thousand years, it does not seem that making such decisions is becoming any more straight forward. With an abundance of competing ethical systems and frameworks for their application in real life, the clinician is still often not sure how to proceed in the face of ethical dilemmas, either due to a lack of background ethical knowledge or experience in applying it. This paper will discuss whether considering what one would expect one’s friend to do if one was the patient, or what would one think they would do for a friend if they were the patient, can be a helpful, more intuitive, tool for clinical decision-making that can produce outcomes that are congruent with major ethical systems.

Recently, neuroscientists have become increasingly interested in studying the interactions between information sampling and choice and the mechanisms underlying these. In machine learning, introducing intrinsic rewards for exploration has been found to greatly improve artificial agents’ performance on ‘hard exploration’ problems. There is evidence that humans are intrinsically driven to sample both information that has no direct impact on reward outcome as well as information that reduces uncertainty on upcoming decisions. Recent findings from studies using a range of information sampling tasks suggest a functional dissociation between more posterior and anterior regions of prefrontal cortex (PFC). Specifically, pre-supplementary motor area (pre-SMA) and dorsal anterior cingulate cortex (dACC) are involved in decisions to sample more information to guide upcoming decisions, whereas the more anterior ventromedial prefrontal cortex (vmPFC), encodes the value of upcoming information. We argue that to effectively study information sampling in humans, the behavioral tasks we use must better reflect the large state space available to humans in real life. This, however, is challenging due to the complex model of the world humans have access to when choosing where to sample next.

To evaluate the efficacy and safety of levilimab in COVID-19 patients in the real-life clinical practice.

Although you do not know the subtleties of the Cubism art movement, we know that it has important representatives such as Pablo Picasso and Georges Braque. Cubism is an art movement that emerged from the collaboration between Pablo Picasso and Georges Braque in France at the beginning of the 20th century. Based on the geometric abstraction of the Fauvism movement, Cubism broke many of the conventions of traditional Western art styles. Two of the mostdistinctive features of cubist paintings are the use of an abstract, "four-dimensional" perspective and the fragmentation of scenes and people into geometric shapes. When you look at a photograph or a scene in real life, you are viewing the scene from a single perspective. All objects in the frame fit together in this single perspective. Picasso was not only the central figure of Cubism, but also an internationally renowned painter and sculptor, considered one of the mostinfluential artists of numerous artistic movements, as well as a practitioner of other art forms such as drawing, engraving, book illustration. Cubism is the most influential movement in modern art, and Picasso and Braque transformed the art world in a way that no figure before him could. In this article, it is examined to present a definition of Cubism, to discover the roots of the Cubist movement, to follow its developments in the first half of the 20th century, and its most influential representatives Picasso and Braque.

Wireless Sensor Network (WSN) takes a major part in the world of technology and everyday lives by implementing Internet of Things (IoT) sensors into many kinds of environment such as agricultural area. Many farmers had applied WSN to help them to ease the tasks of tracking and collecting the important data status of their farms and greenhouses in order to maintain its ideal temperature, humidity and lights exposure. Despite these advantages, the WSN security issues could be questioned due to the possibility of being infected by the Distributed Denial of Service (DDoS) from the attackers. Sinkhole attack is the most common DDoS attack that happened in the agriculture environment WSN by sending a fake fastest route to the sensor nodes in the system. Therefore, this project has proposed an Intrusion Detection System (IDS) to detect the sinkhole attacks in the network of agriculture based WSN. The project ran with three simulations of network topologies to show the comparison based on the network traffic performance. The simulations consist of attack-free network, a network with sinkhole attack and IDS in the malicious sinkhole network. The main simulator for the study was Cooja Network Simulator, which was used to conduct all three simulations, while Wireshark was utilised to capture network traffic performance. For every simulation, 20 sensor nodes were implemented due to the facts that the number of the nodes are majorly and ideally used in real life environment of agriculture area. The findings showed that by implementing IDS in the agriculture WSN will gives better results in network traffic performances comparing to the attack-free network and sinkhole network without IDS. Thus, it proved that the proposed IDS could detect the network when uncommon behaviour appeared in the network topologies.

Shunting of trains is a task that requires meticulous adherence to all steps to guarantee safety for everyone involved during and after the procedure. These steps are currently taught using classical teaching materials, such as printouts, videos and training by experienced supervisors. However, due to limited availability of locomotives, hours for training and manpower, training of shunting operation becomes challenging in real life. In this paper, we implemented a lifelike, collaborative virtual environment for shunting training including a novel human factors evaluation system for fatigue and stress monitoring. An experiment with 12 subjects and 3 trainers has been designed and carried out to validate the usage of VR-based shunting training. Positive feedback toward the VR-based training was obtained from the subjects and trainers.

Ensinar Matemática numa perspectiva inclusiva requer garantir o direito de todos a aprendê-la. Para tal, existe uma certa produção científica que auxilia os processos de ensino e de aprendizagem. Todavia, aprender Probabilidade e Estatística apresenta especificidades, visto que, na vida real, muitos fenômenos não são determinísticos, envolvendo a noção de variabilidade e aleatoriedade. Diante disso, o objetivo desta pesquisa foi mapear e analisar as produções científicas brasileiras sobre o ensino e a aprendizagem de Probabilidade e Estatística na perspectiva da Educação Inclusiva. A busca foi realizada no Banco de Teses e Dissertações da CAPES, em 33 periódicos científicos da área de Educação Matemática, Educação Inclusiva e Educação Especial e nos anais do I Encontro Nacional de Educação Matemática Inclusiva. Foi realizada a Análise de Conteúdo dos nove trabalhos selecionados que evidenciaram avanços na fundamentação teórica destes trabalhos, predominância de pesquisas na Educação Especial e necessidade de novas pesquisas, principalmente no Ensino Médio.

Introduction: Inhalers are the most commonly used devices for lung drug delivery in asthma and COPD. Inhaler use offers several advantages but requires the user's proper mastery. The issue of inhaler technique is very important as inhaler misuse remains common in real life regardless of the inhaler used and is associated with poor disease control.Areas covered: Across a PubMed® literature search and evaluation for English publications on inhaler use conducted up to January 2021, this narrative review analyses the key-steps of inhaler mastery and the significance of the errors of use for the main devices. There are uncertainties on many tasks of inhaler use and on those variations from recommended steps that are considered as critical errors.Expert opinion: Despite technological advancements, an easy-to-use device is not yet available. Whatever the chosen inhaler, health care givers' proper practical education with the opportunity of feedback learning has a key-role for improving inhaler technique,, but is time-consuming, and remains limited to few successful experiences. Newer digital technologies will be applied to the field of inhaler education, but the lack of knowledge on many practical aspects of inhaler technique might be a limit for its extensive implementation. Possibly digital innovation might substantially contribute to reduce inhaler misuse only if clinicians, manufacturers, and subjects will cooperate together on this issue.

This article explores the performance of agency within the context of unequal power resources and structural constraint. Based on 23 video‐recorded placement meetings in three homeless shelters, we find that participants' agency is the outcome of both collaboration and resistance. To avoid interaction that fails to empower, social actors engage in “repair work” and face‐saving practices. When clients display “wrong face”—that is, bring problems to the table that are not considered “reasonable”—then the service providers engage in “repair work.” Participants turn conflict into collaborative agency because interactions that fail to deliver mutually empowering forms of agency have costs for both: clients' problems are not solved, and service providers fail to reach organizational goals.

Noise emission from individual vehicle largely contributes to city pollution and has serious health impact. The standards towards vehicle manufactures consists in pass-by testing with specific acceleration conditions which are not representative of all real driving. For the 2015/996 EU directive, the vehicle source model is inspired of the preceding pass-by standard with derived data represented the propulsion and rolling noise sources. Anyhow, those sources are underestimated due to driving behavior, aged and modified vehicle, road surface, meteorological conditions... The true data collection of vehicle pass-by would be interesting. Moreover, some of the countries are reflecting on how to fight against those extremely noisy vehicle exceeding noise limit with efficient monitoring systems. This paper presents an innovative tool able to detect, identify and quantify the noise emission of individual pass-by vehicle in real life traffic. It is based on the combination of array and video processing. Compared to the state of the art and thanks to MEMs technology, the system is optimized and designed to quantify the individual noise vehicle emission regarding standard with controlled measurement and accurate processing. If the conditions are not respected to properly qualify the pass-by regarding the system limits, the data are ignored. It aims at constructing large and accurate database useful to determine average noise levels and/or acceptable noise limits per vehicle category.

The variants and patterns of Islamic economic thought from Islamic scholars provide a roadmap for Islamic economic empowerment and development. The economic activities of the Islamic community should refer to the concept of Islamic economics that has been built by the mujtahids. The principles of Islamic economics globally have historical equivalents to be used as the basis for Islamic economics from upstream to downstream. Islamic society only needs the will to implement it in real life in everyday life

The NOx gasses (NO and NO2) are among the most important air pollutants due to the toxicity of NO2, as well as the role of NOx in the tropospheric oxidation of Volatile Organic Carbons (VOCs), contributing to the formation of other hazardous air pollutants. Air pollution is one of the biggest health threats worldwide; hence reducing NOx levels is an important objective of the UN sustainable development goals, e.g., #3, “Good health and well-being” and #11 “Sustainable cities and communities.”Photocatalysis using TiO2 and light is a promising technique for removing NOx along with other pollutants, as demonstrated on a laboratory scale. Furthermore, a long-range of real-life test studies of varying scales have been conducted during the past two decades. The results of these studies have been conflicting, with some studies reporting no effect on the ambient air quality and others reporting significant reductions of NOx levels. However, the studies are very difficult to compare and assess due to the different approaches used, which consequently vary in quality. In this review, we aim to develop a set of objective evaluation criteria to assess the quality of the individual studies in order to simplify the interpretation and comparison of the existing studies. Moreover, we propose some guidelines for future test studies. Furthermore, the approaches and main conclusion from 23 studies are independently assessed and discussed herein.

Dapagliflozin is the first novel SGLT2 inhibitor for the treatment of Type 2 diabetes. The aim of this study was to evaluate its effectiveness and safety in a real-life clinical setting. We analyze data from four hospitals on patients initiated on dapagliflozin. HbA1c, weight and daily insulin dosage was recorded at baseline and 6 months follow-up.229 patients received dapagliflozin. At baseline, mean HbA1c was 82mmol/mol(186) and mean weight was 102 kg(n=159).The average reduction in HbA1c at 6 months (n=121) was 13mmol/mol whereas the average reduction in weight(n=96) was 2kg.A mean reduction in daily insulin requirement(n=41) by 12 units(13%) at 6 months compared to baseline was noted. Nine patients developed candidiasis, eight developed UTI, five reported symptoms of thirst and five developed hypoglycaemia out of which four were on insulin and one on gliclazide. Ten patients discontinued(4%) dapagliflozin due to side effects. Our results confirm that dapagliflozin can be used safely and effectively in a real-life setting. Keywords: Dapagliflozin, real world, SGLT2, Type 2 diabetes. Continuous...

Background In order to predict and prevent falls and fall-related injuries, it is crucial to understand the motor control for crossing obstacles. In real life, since obstacles do not always take regular shapes like rectangles, the lead and trail limbs sometimes need to negotiate different obstacle heights. The interlimb interaction in this process has remained unknown, since obstacle crossing studies commonly use a single-obstacle paradigm in which the obstacle height is the same for the lead and trail limbs. Research question We used a dual-obstacle paradigm to test whether the foot clearance over one obstacle was influenced by the contralateral obstacle’s height. Methods Sixteen healthy young male and female participants (age: 22.5 ± 1.9 years) crossed over two obstacles placed side by side. Four obstacle conditions were made by combining obstacles of two heights (low, L, 9.0 cm; high, H, 22.5 cm) of the obstacles.In the LL condition, both obstacles were low, and in the LH condition, there was a low obstacle for the lead limb and a high one for the trail limb. Similarly, we also arranged HL and HH conditions. Each subject performed 20 trials per condition. We compared the vertical foot clearance, prestep distance, and poststep distance between the conditions. Result The foot trajectory to step over the obstacles were affected by the contralateral obstacle’s height. The vertical foot clearance of the trail limb was greater in the HL condition than in the LL condition. The vertical foot clearance of the lead limb was greater in the LH condition than in the LL condition. Significance The results suggest that the foot trajectory was not determined exclusively by the obstacle to be crossed. Instead, comprehensive information, including the height of the obstacle for the other limb, might be used for motor control during obstacle crossing.

In this paper, the natural frequencies of exponential functionally graded beams are determined from two separate formulations, one based on an analytical approach and the other based on a numerical approach. The classical beam theory is carried out with various boundary conditions. The results obtained in this paper are presented and compared with other results in the references to verify the correctness in implementing the formula and writing the Matlab code. This paper can help researchers have an overview of the vibration characteristics of the exponential functionally graded beams. Furthermore, they can enhance their research by modifying more advanced materials such as beams reinforced by graphene platelets, beams' shape, etc. Last but not least, with the strong application of the functionally graded material in real life, it would be good if there were more data related to this issue.

Technology domestication in old age may promote autonomy and support aging in place, but most previous research did not follow the process of domestication over time and in real life conditions. To...

This research examines the hopelessness described in the poems by J. C. Dawn entitled Living in A Pride World, Womb, and A Soundless Tear in her book The Ripple of Existence. This research is a descriptive qualitative study that aims to describe the words used to express hopelessness. The method used to analyze the poems is the analysis of intrinsic elements in poetry with a psychological approach to find out about hopelessness experienced by the characters in each poem. Hopelessness is a condition experienced by anyone where where there is no more hope. This would also be contextualized in real life concerning the stages of someone experiencing hopelessness based on Abramson's theory. The results of the research show that the "I" character in the first poem experiences a failure in himself; in the second poem, "I" faces struggles under challenging conditions and in the third, "she" finds herself unable to accept the reality of life.

The development of technologies such as employment tracking systems, personal security, and the use of robots has led a lot of studies on face recognition systems. In the most of studies considering face recognition, recognition accuracies are very high, since training and testing images are selected randomly from the same databases. However, in real life applications, these images are not randomly selected from the same database. Because, these systems are trained during installation of the recognition system or when a new person needs to be introduced to the system. On the other hand, images used for predictions are uploaded to the system at other times. In this study, it is aimed to show that the accuracy rates of real-life face recognition systems differ from the systems trained and tested with randomly selected images as usually done in literature. To observe this difference in the first step, training and test images are selected randomly. In the second step, training and test images are divided according to the recording dates as in real life. Accuracy rates are evaluated by using linear discriminant analysis, local binary patterns and principal component analysis methods. Although the accuracies are very high for the first step, it is seen that the accuracies fell dramatically in the second step for all methods. Afterwards a new method is searched also in this study to increase these low accuracy rates. It is shown that usage of eye area images instead of face images has higher accuracy rates in all above methods for real life applications.

It is well known that different names of color can lead to distinct attractions to people. To study the neural mechanism underlying this phenomenon, an implicit association test task was designed for color names, in which participants were required to select the possible meanings of a Greek phrase from two color names (in Chinese). The behavioral results showed that the participants were more likely to select novel names for long Greek phrases and dates names for short Greek phrases. The EEG results showed that the mean amplitude of N1 was greater for selections of novel color names than selections of dates names for Greek phrases. Meanwhile, the mean amplitude of N3 for novel color names was more negative than that of dates color names. Significant interaction effect of N3 was also found for the four kinds of selections between Greek phrases and Chinese color names. Moreover, a frontal-positive and occipital-negative distribution for scalp topography of N1 was found, while the scalp topography of N3 was opposite as frontal-negative and occipital-positive distribution, suggesting the importance of visual cortex for perception of the color names and prefrontal cortex for integration and decision of selection. In summary, the results here indicated that colors with novel names could easily attract people’s attention than colors with dates names, which might shed light on the usage of color names in real life. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11571-021-09685-y) contains supplementary material, which is available to authorized users.

Swear words express and arouse emotions and due to their taboo-contravening origin are charged with an offensive potential. By mirroring the functions they perform in real life, they contribute to ...

The aim of this paper is to determine the fatigue damage of structures subject to random vibrations generated by Qualmark chamber. In real life, structures are generally subjected to complex multia...

The Contextual-based videos link material with concepts contained in real life. So, it produces learning that is appropriate to student context. Contextual learning emphasizes the process of full student involvement to be able to understand the material being studied and relate it to life situations. This study aims to determine the differences in the improvement of learning outcomes, learning activities, and student learning responses to the use of contextual-based instructional video media. Data collection techniques used were observation, tests, and a survey to respondents in the form of questionnaire questions on contextual-based learning video assessments. The research was conducted at SMA NU Juntinyuat. The design of this study was the Control Group Pretest-Posttest design. One group was given a treatment (experimental group) and the other was not treated (control group). The results showed that: (1) there was a significant difference in student learning outcomes between the experimental class and the control class, (2) the average percentage of student learning activities increased to 92%. (3) The percentage of the average student response questionnaire as a whole is 83% with very strong criteria.

Continuous developments in automotive technology brought about the reality of having an increasing number of autonomous vehicles (AV) on roadways soon. However, this advancement comes with the uncertainty of how the interaction between the autonomous and non-autonomous (non-AV) vehicles will play out. Using traffic simulators to model both AVs and non-AVs, and studying the effect of AVs on roadway mobility can help researchers in learning what to expect in real life. In this paper, an open-source simulator called Simulation of Urban Mobility (SUMO) was used to develop AVs by modifying Intelligent Driver Model (IDM) car following and LC2013 lane changing models. Then, three actual roadways in Columbus, Ohio were modeled, and 40 simulations were run for each traffic network. The first set of simulations focused on the impacts that AVs have on vehicle roadway mobility with non-AVs when all the AVs have the same autonomy level. The second set of simulations had mixed AV autonomy levels (SAE Level 2, 3 and 4) with mixed AV and non-AV traffic. The analysis revealed that mobility of AVs and non-AVs increased generally as autonomy level increased. When the AV autonomy levels were mixed, the non-AVs experienced lower average speeds and decreased roadway mobility.

This paper presents a unique perspective into challenges faced by kindergarten teachers in engaging children in Science, Technology, Engineering, Arts and Mathematics (STEAM) education in Vietnam. ...

Objective To validate the Delirium Diagnostic Tool (DDT-Pro) in a SNF and compare its performance to the 4 A's Test (4AT) in real life conditions. Methods Prospective cross-sectional study of 262 consecutively admitted adults to a SNF, independently assessed by psychiatrists using DSM-5 delirium criteria and by geriatricians using the DDT-Pro (0–9 points) and 4AT (0–12 points). Results 141 (53.8%) participants had dementia and 79 (30.1%) had delirium. DDT-Pro and 4AT were moderately correlated (−0.59). Accuracies against DSM-5 diagnosis ranged from 80 to 85% and were comparable between tools regardless of dementia. Recommended delirium cutoff for the DDT-Pro (≤6) had 77.2% sensitivity, 84% specificity, and NPV = 89.5% and 4AT (≥4) had 54.4% sensitivity and 92.9% specificity, with lower specificity in the dementia subsample. DDT-Pro sensitivity increased (84.8%) at ≤7cutoff. Sensitivity and specificity of all DDT-Pro and 2/4 4AT items displayed gradients along severity levels, but two dichotomously rated 4AT items had low positivity. The tools had low concordance (p Conclusions DDT-Pro is valid to detect delirium in SNF population where simple, structured tools with high sensitivity are needed. DDT-Pro items assess the three core domains of delirium as a continuous measure and may have advantages over the 4AT.

Event-based social networks (EBSNs) connect online and offline lives. They allow online users with similar interests to get together in real life. Attendance prediction for activities in EBSNs has attracted a lot of attention and several factors have been studied. However, the prediction accuracy is not very good for some special activities, such as outdoor activities. Moreover, a very important factor, the weather, has not been well exploited. In this work, we strive to understand how the weather factor impacts activity attendance, and we explore it to improve attendance prediction from the organizer’s view. First, we classify activities into two categories: the outdoor and the indoor activities. We study the different ways that weather factors may impact these two kinds of activities. We also introduce a new factor of event duration. By integrating the above factors with user interest and user-event distance, we build a model of attendance prediction with the weather named GBT-W , based on the Gradient Boosting Tree. Furthermore, we develop a platform to help event organizers estimate the possible number of activity attendance with different settings (e.g., different weather, location) to effectively plan their events. We conduct extensive experiments, and the results show that our method has a better prediction performance on both the outdoor and the indoor activities, which validates the reasonability of considering weather and duration.

Background: In the treatment of idiopathic pulmonary fibrosis (IPF), nintedanib and pirfenidone, with their different mechanisms of action, lead to a reduction in the rate of progression of the fibrosis process measured by the reduction of functional decline, and, in particular, the decrease in forced vital capacity (FVC) and of the diffusion capacity of the lungs for carbon monoxide (DLCO). The objective of this study was to analyze real-life adherence, persistence and efficacy in the use of pirfenidone and nintedanib in the treatment of IPF. Methods: A non-interventional multicenter retrospective observational pharmacological study in real-life treat-ment at 1 and 2 years was conducted. Furthermore, we analyzed the levels of FVC and DLCO at 6 and 12 months, respectively, from the start of treatment. Results: We identified 144 patients in the period between January 2013 and April 2019. From the point of view of adherence, there is no difference between the two drugs, even though patients who used pirfenidone had increasingly higher values: 0.90 vs 0.89, in the first year, and 0.91 vs 0.84, in the second year. In the first year of treatment, the percentage of persistent patients was 67% and 76%, while in the second year, it dropped to 47% and 53% for pirfenidone and nintedanib, respectively. Conclusion: The stratification of the adherence values as a function of the response to treatment in terms of FVC at 12 months for both study drugs showed that patients with optimal response scored adherence of more than 90%.

Discipleship today has again become a principal concern, was greeted with positive and implemented practically in the Lord's church, including the church-based mandarin which will be the object of research journal. However the fact is, after going through a preliminary study in the form of informal conversations with some of the Servants of the Lord and of the Assembly representing some church-based mandarin, the authors noticed that even though discipleship approved by a majority of the Servant of the Lord as an important thing that must be done, however there are still many of the church who have not done it in a concrete way in real life. Seminar after seminar and training for the sake of training has been held, in great demand and was followed by thousands of people from dozens of even hundreds of church, however only a handful of the church has been run in real time and sustainable. Considering the importance of discipleship which is the great mission of Jesus, not just an option or optional, even though there are many aspects that can be examined in the subject of discipleship, the authors will focus his research on the obstacles that may arise in the implementation of discipleship practically in the church, in particular that based on mandarin. Therefore, the authors wanted to examine further, the first about the essence of discipleship itself, and continued with research on the constraints, obstacles and challenges that make this discipleship can't be implemented in churches, in particular that based mandarin where the author to worship and serve.

Purpose In real life, we only know the consequences of each possible action with some uncertainty. A typical example is interval uncertainty, when we only know the lower and upper bounds on the expected gain. A usual way to compare such interval-valued alternatives is to use the optimism–pessimism criterion developed by Nobelist Leo Hurwicz. In this approach, a weighted combination of the worst-case and the best-case gains is maximized. There exist several justifications for this criterion; however, some of the assumptions behind these justifications are not 100% convincing. The purpose of this paper is to find a more convincing explanation. Design/methodology/approach The authors used utility approach to decision-making. Findings The authors proposed new, hopefully more convincing, justifications for Hurwicz’s approach. Originality/value This is a new, more intuitive explanation of Hurwicz’s approach to decision-making under interval uncertainty.

In the study of two-sided matching decision problems, preference ordinal information is a key factor. However, in real life, it is often difficult to ascertain complete preference ordinal informati...

BACKGROUND: The COVID-19 pandemic forced the implementation of social distancing and circulation restrictions. This affected all aspects of society including health care. In the field of chronic neurological disorders such as Parkinson's disease (PD), teleneurology is employed in scenarios where face-to-face interactions are not possible. A growing number of clinicians and institutions are turning to teleneurology in order to providing medical care. AIMS OF THE ARTICLE: In this manuscript, we present a practical, 'how we do it in real life', example of a teleneurology appointment with a person with PD (PwP). METHODS: We elaborated a step-by-step approach of the main aspects of a consultation with a PwP and provide video illustration. RESULTS: The key aspects of a teleneurology appointment were separated into: (1) In the office, before the appointment; (2) History taking; (3) Examination; and (4) Finishing up. CONCLUSIONS: We discuss the strengths and weaknesses of this approach and provide our experience in overcoming commonly encountered difficulties.

Eric Senbel,1 Sonia Tropé,2 Hélène Herman-Demars,3 Elena Zinovieva,3 Agnès Courbeyrette,3 Pierre Clerson,4 Yann Fardini,4 René-Marc Flipo5 1Rheumatology Office, Marseille, France; 2French National Patient Organization Against Rheumatoid Arthritis (ANDAR), Montpellier, France; 3Medical Department, Nordic Pharma, Paris, France; 4Soladis Clinical Studies, Roubaix, France; 5University of Lille, Rheumatology Department, Hôpital Roger Salengro, Lille, FranceCorrespondence: Yann FardiniSoladis Clinical Studies, 15 Boulevard Du Général Leclerc, Roubaix, 59100, FranceTel +33 6 46 32 95 85Fax +33 3 28 09 94 76Email yfardini@soladis.frPurpose: The purpose of the APRIM study (for Adherence Polyarthrite Rhumatoïde Injection Methotrexate) was to investigate the change in treatment adherence of patients with rheumatic arthritis (RA) who switched from oral to subcutaneous methotrexate (MTX).Patients and Methods: Prospective, observational study in RA patients treated with MTX and switching from oral to subcutaneous (SC) route in real-life conditions. Data on motivations for switch, disease activity (DAS28-CRP), quality of life (AISM-2 SF), disability (HAQ-DI), and adherence to MTX were collected at inclusion (M0) and 6 months later (M6). Adherence was assessed by the 8-item Morisky Medication Adherence Scale (MMAS-8) and defined as high (MMAS-8 = 8), medium (MMAS-8 = 6 or ≤ 8) or low (MMAS-8 < 6). The primary evaluation criterion was the proportion of patients who maintained strong adherence or improved adherence by at least one category (from low to medium or strong or from medium to strong) between M0 and M6.Results: The analysis involved 207 patients (age 60.4± 12.7 years, 75.2% females). 6.7% were in remission and 15.5% had low disease activity (LDA) at baseline. 58.5% reached the primary criterion and strong adherence rate increased from 42.0% to 50.7%. Change of route was combined with increased MTX dose in 34.8% of patients. Switch to SC route increased the proportion of patients with remission or LDA from 22.8% to 52.9% and increased quality of life even in patients with unchanged MTX dose.Conclusion: Overall, change from oral to SC route improved adherence to MTX, RA control and quality of life independently of change in MTX dose.Keywords: rheumatoid arthritis, methotrexate, oral, subcutaneous, compliance, switch

The protection of user private data has long been the focus of AI security. We know that training machine learning models rely on large amounts of user data. However, user data often exists in the form of isolated islands that can not be integrated under many secure and legal constraints. The large-scale application of image steganalysis algorithms in real life is still not satisfactory due to the following challenges. First, it is difficult to aggregate all of the scattered steganographic images to train a robust classifier. Second, even if the images are encrypted, participants do not want irrelevant people to peek into the hidden information, resulting in the disclosure of private data. Finally, it is often impossible for different participants to train their tailored models. In this paper, we introduce a novel framework, referred to as FedSteg, to train a secure, personalized distributed model through federated transfer learning to fulfill secure image steganalysis. Extensive experiments on detecting several state-of-the-art steganographic methods i.e., WOW, S-UNIWARD, and HILL, validate that FedSteg achieves certain improvements compared to traditional non-federated steganalysis approaches. In addition, FedSteg is highly extensible and can be easily employed to various large-scale secure steganographic recognition tasks.

Purpose: To report the visual and anatomic outcomes in treatment-naïve neovascular age-related macular degeneration (nAMD) patients treated with aflibercept under a standardized Treat and Extend (T&E) protocol for up to 3 years of follow-up in “real-life” practice. Methods: This retrospective, observational, multicenter study included patients with treatment-naïve nAMD and at least 12 months of follow-up. T&E regimen adjustment was initiated after loading phase. At each visit best-corrected visual acuity (BCVA) and optical coherence tomography parameters were performed. Results: One hundred and thirty-six eyes of 115patients had at least 1 year of follow-up with 114 and 82 eyes completing at least 2 and 3 years of follow-up, respectively (mean follow-up duration: 2.7 ± 1.3 years). Mean age was 78.6 ± 8.6 years old and 52% were women. Mean BCVA increased from 60.6 ± 18.7 letters at diagnosis to 66.9 ± 16.2 letters at 1 year (+6.3 letters, p = 0.003) and remained stable throughout the follow-up period (63.1 ± 20.3 letters (+2.5, p = 0.1) and 64.0 ± 20.1 letters (+3.4, p = 0.27) at 2 and 3 years, respectively). The mean central retinal thickness decreased significantly from 358.2 ± 87.9 µm at baseline to 302 ± 71.7 µm at 12 months and maintained stable after 36 months of follow-up (297.1 ± 76 µm, p Conclusions: Our study demonstrated that intravitreal injections of aflibercept initiated under a standardized T&E for patients with treatment-naïve nAMD allow for significant visual improvement at 12 months, which was maintained over a 3-year follow-up period.

21st-century learning should include STEM to grow interested in the Indonesian nation to love and master science, technology, engineering, and mathematics. They are included in it for physics learning. STEM is a practical learning approach because it combines knowledge, mathematics, technology, and techniques. This aim to make students as problem-solvers, inventors, have innovation, independent logical thinking, technological literacy, connect their culture and history with education, and apply their knowledge in real life. Thus, it is necessary to implement STEM-based learning integrated lokal wisdom /culture of the community in which the learners are located. One of the lokal wisdom of coastal communities in Maluku is Timba Laor. This research aims to develop a High School Physics Learning Tool business concept, and STEM-based Energy integrated lokal wisdom Timba Laor in the village of Allang Central Maluku district, a valid, practical, and effective Plomp model. The stages of mining carried out in this research activity are the development of high school physics learning tools business concept and STEM-based Energy integrated lokal wisdom Timba Laor in the village of Allang Central Maluku District. Test models by providing surveys of physics teachers to empirically validate the learning devices that have been compiled, analyzed, and revised. The resulting product is a learning device physics high school concept business, and energy-based STEM integrated lokal wisdom. Keywords : Business and Energy, Learning Tools, STEM, Timba Laor

This study aims to determine the process of a person's interaction on Tinder social media, causing a new phenomenon known as catfishing. This research uses a qualitative approach. The data collection technique was obtained by using in-depth interview techniques. The results of the study show that the self-presentations displayed by Tinder users are not using their real photos or identities. The scope of self-presentation shown in this study does not extend to false identity or paint through identity theft. Tinder users in this study tended to use their original photos that they had edited to look better and closer to the ideal Tinder users liked, use their old photos that were considered better and closer to ideal, blur their original photos, use their real photos but not using real names, to using photos of objects or objects that interest them to show their interests and hobbies to other users. In this study, there were no users who used other people's existing identities either by using other people's photos or identities that showed someone who was in real life.

Background Plaque psoriasis significantly affects patients’ health-related quality of life. To aid treatment decisions, not only objective assessment by physicians but also subjective assessment by patients is important. Objective To assess the significance of Dermatology Life Quality Index (DLQI) evaluation at the time of biologics introduction in clinical practice in Japanese patients with plaque psoriasis. Methods This was a single-arm, open-label, multicenter study. At baseline, Psoriasis Area and Severity Index (PASI) and DLQI scores were measured and stratified based on DLQI scores ≥6/≤5 and PASI scores ≤10/>10. Other patient-reported outcomes assessed included EQ-5D-5L, itch numerical rating scale (NRS), skin pain NRS, Generalized Anxiety Disorder-7 (GAD-7), Patient Health Questionnaire-8 (PHQ-8), Sleep Problem Index-II (SPI-II), and Treatment Satisfaction Questionnaire for Medication-9 (TSQM-9). Results Of the 73 enrolled patients, 23 had PASI scores ≤10. Those with PASI/DLQI scores >10/≥6 had a significantly higher median PASI score than those with PASI/DLQI scores >10/≤5 (p = 0.0125). Regardless of PASI scores (>10/≤10), median itch NRS and GAD-7 scores were significantly higher in patients with DLQI scores ≥6 than in those with DLQI scores ≤5 (itch NRS, p = 0.0361 and p = 0.0086, respectively; GAD-7, p = 0.0167 and p = 0.0273, respectively). Patients with PASI/DLQI scores ≤10/≥6 had significantly higher skin pain NRS (p = 0.0292) and PHQ-8 (p = 0.0255) scores and significantly lower median SPI-II scores (p = 0.0137) and TSQM-9 Effectiveness domain scores (p = 0.0178) than those with PASI/DLQI scores ≤10/≤5. Conclusion DLQI may be useful for assessing patients’ concerns that cannot be identified by PASI alone while initiating biologics or switching from other biologics in clinical practice.

BACKGROUND Teaching caregivers to respond to normal infant night awakenings in ways other than feeding is a common obesity prevention effort. Models can simulate caregiver feeding behavior while controlling for variables that are difficult to manipulate or measure in real life. METHODS We developed a virtual infant model representing an infant with an embedded metabolism and his/her daily sleep, awakenings, and feeds from their caregiver each day as the infant aged from 6 to 12 months (recommended age to introduce solids). We then simulated different night feeding interventions and their impact on infant body mass index (BMI). RESULTS Reducing the likelihood of feeding during normal night wakings from 79% to 50% to 10% lowered infant BMI from the 84th to the 75th to the 62nd percentile by 12 months, respectively, among caregivers who did not adaptively feed (e.g., adjust portion sizes of solid foods with infant growth). Among caregivers who adaptively feed, all scenarios resulted in relatively stable BMI percentiles, and progressively reducing feeding probability by 10% each month showed the least fluctuations. CONCLUSIONS Reducing night feeding has the potential to impact infant BMI, (e.g., 10% lower probability can reduce BMI by 20 percentile points) especially among caregivers who do not adaptively feed. IMPACT Teaching caregivers to respond to infant night waking with other soothing behaviors besides feeding has the potential to reduce infant BMI. When reducing the likelihood of feeding during night wakings from 79% to 50% to 10%, infants dropped from the 84th BMI percentile to the 75th to the 62nd by 12 months, respectively, among caregivers who do not adaptively feed. Night-feeding interventions have a greater impact when caregivers do not adaptively feed their infant based on their growth compared to caregivers who do adaptively feed. Night-feeding interventions should be one of the several tools in a multi-component intervention for childhood obesity prevention.