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Aim: To study the early stages of sensory (P50 suppression) and sensorimotor (prepulse modification of acoustic startle reaction - ASR) information processing in aggressive and non-aggressive patients with schizophrenia., Material and Methods: Two groups (aggressive group A, 44 s. and non-aggressive group NA, 27 s.) and 48 healthy people were studied using oculography and encephalography. Symptoms of schizophrenia were assessed by PANSS., Results and Conclusion: The analysis of ASR and P50 revealed the increased ASR latency, deficit of prepulse inhibition (PPI) with 60 ms leading interval, and P50 suppression in patients compared to controls. Aggressive behavior impacted on lateral features of ASR changes in the group A. The increase of ASR amplitude and the decline of prepulse facilitation were found in the group NA. The P50 analysis revealed the increased P50 amplitude and the shortened latency in response to 2nd stimulus in the pair. The increase in scores on item G14 of the PANSS (Poor impulse control) in the group A and its correlations with ASR and P50 parameters in this group suggested the important role of impulsivity in aggressive behavior in the studied sample of aggressive patients. ASR and P50 characteristics in the group NA are associated with increased sensitivity to incoming stimuli and such personality traits as increased alertness and fear, which might inhibit aggression. Thus, indicators of the early stages of information processing can be considered as potential predictors of aggressive behavior.

Aim: The identification of clinical-psychopathological and pathopsychological components involved in the formation of syndromes of delusional and overvalued constructions., Material and Methods: Authors examined 93 subjects using experimental psychological techniques for detection of cognitive styles., Results and Conclusion: A specific combination of phenomenological disorders and cognitive style characteristics in different types of delusional (sensual, imaginative and interpretive) and delusion-like (overvalued) states has been singled out. It has been shown that a specific combination of different cognitive-motivational controllers of intellectual process underlies the mechanisms of these disorders. It is a basis for the formation of specific structures of pathological personal meanings with the dominance of imaginative or ideational patterns or deformations of the semantic significance of the stimuli.