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11 results on '"Ilaria Clementi"'

1. Temporary intravascular shunts and limb salvage in civilian vascular trauma

Author

Ombretta Martinelli, Francesca Miceli, Simone Cuozzo, Francesco Giosuè Irace, Stefano Avenia, Immacolata Iannone, Ilaria Clementi, Paolo Sapienza, and Maria Irene Bellini

Subjects
trauma, limb salvage, amputation, vascular injury, vascular shunt, Surgery, RD1-811
Abstract

BackgroundTemporary intravascular shunts (TIVS) may allow quick revascularization and distal reperfusion, reducing the ischemic time (IT) when an arterial injury occurs. Furthermore, TIVS temporarily restore peripheral perfusion during the treatment of concomitant life-threatening injuries or when patients require evacuation to a higher level of care. Notwithstanding, there are still disputes regarding the use of TIVS, in view of the paucity of evidence in terms of potential benefits and with regard to the anticoagulation during the procedure. The present study aimed to assess TIVS impact, safety, and timing on limb salvage in complex civilian vascular traumas.Patients and methodsData were retrieved from the prospective database of our department, which included all patients hospitalized with a vascular injury of the extremities between January 2006 and December 2022. Patients undergoing TIVS during vascular injury management were included in group A, and those who could not postpone immediate care for TIVS insertion were included in group B (control group). Data concerning the times required for extremity revascularization or other surgical procedures such as orthopedic interventions and the time of limb ischemia were compared between the two groups. A comparison of the postoperative course between the two groups was also performed.ResultsA total of 53 patients were included: group A (TIVS insertion, n = 31) and group B (control, n = 22). Revascularization time significantly differed (p = 0.002) between the two groups, which is lower in group A (4.17 ± 2.37 h vs. 5.81 ± 1.26 h). TIVS positively affected the probability of limb salvage (p = 0.02). At multivariate analysis, the factors independently associated with limb salvage were TIVS usage, the necessity of hyperbaric oxygen therapy, and the total IT. In group A, there were three deaths and one major amputation, and in group B, there were two deaths and four major amputations.ConclusionsThe use of TIVS minimizes revascularization time and improves limb salvage probability. A multidisciplinary approach is recommended, and correct surgical timing is key to ensure the best outcome.

Published
2023
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2. High-resolution anoscopy predictive modeling of anal canal cancer response after definitive chemoradiotherapy in COVID19 era

Author

Francesca De Felice, Ilaria Clementi, Valeria Converti, Daniele Crocetti, Paolo Sapienza, Nadia Bulzonetti, Sassun Richard, Daniela Musio, Andrea Mingoli, and Vincenzo Tombolini

Subjects
High-resolution anoscopy, HPV, Anal canal cancer, Radiotherapy, Response, Treatment failure, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Purpose: To develop a predictive index model, integrating both clinical and high-resolution anoscopy (HRA) features to further personalize the decision making process in anal canal carcinoma in COVID19 era. Methods and materials: We assess HRA parameters after definitive chemoradiotherapy in patients with anal canal malignant lesions. Results: HRA features could be important to assess the effect of CRT and a risk stratification system should be introduced in clinical practice to better allocate therapeutic interventions. Conclusion: To our knowledge this is the first proposal for HRA findings in anal canal cancer after definitive CRT. We believe that a risk score can be useful to estimate the risk of treatment failure (in term of persistence disease and/or recurrence) and its clinical relevance should not to be underestimated.

Published
2023
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3. HPV Vaccination after Primary Treatment of HPV-Related Disease across Different Organ Sites: A Multidisciplinary Comprehensive Review and Meta-Analysis

Author

Violante Di Donato, Giuseppe Caruso, Giorgio Bogani, Eugenio Nelson Cavallari, Gaspare Palaia, Giorgia Perniola, Massimo Ralli, Sara Sorrenti, Umberto Romeo, Angelina Pernazza, Alessandra Pierangeli, Ilaria Clementi, Andrea Mingoli, Andrea Cassoni, Federica Tanzi, Ilaria Cuccu, Nadia Recine, Pasquale Mancino, Marco de Vincentiis, Valentino Valentini, Gabriella d’Ettorre, Carlo Della Rocca, Claudio Maria Mastroianni, Guido Antonelli, Antonella Polimeni, Ludovico Muzii, and Innocenza Palaia

Subjects
human papillomavirus, HPV, vaccination, cervical cancer, vulvar cancer, anogenital warts, Medicine
Abstract

Objective: To assess evidence on the efficacy of adjuvant human papillomavirus (HPV) vaccination in patients treated for HPV-related disease across different susceptible organ sites. Methods: A systematic review was conducted to identify studies addressing the efficacy of adjuvant HPV vaccination on reducing the risk of recurrence of HPV-related preinvasive diseases. Results were reported as mean differences or pooled odds ratios (OR) with 95% confidence intervals (95% CI). Results: Sixteen studies were identified for the final analysis. Overall, 21,472 patients with cervical dysplasia were included: 4132 (19.2%) received the peri-operative HPV vaccine, while 17,340 (80.8%) underwent surgical treatment alone. The recurrences of CIN 1+ (OR 0.45, 95% CI 0.27 to 0.73; p = 0.001), CIN 2+ (OR 0.33, 95% CI 0.20 to 0.52; p < 0.0001), and CIN 3 (OR 0.28, 95% CI 0.13 to 0.59; p = 0.0009) were lower in the vaccinated than in unvaccinated group. Similarly, adjuvant vaccination reduced the risk of developing anal intraepithelial neoplasia (p = 0.005) and recurrent respiratory papillomatosis (p = 0.004). No differences in anogenital warts and vulvar intraepithelial neoplasia recurrence rate were observed comparing vaccinated and unvaccinated individuals. Conclusions: Adjuvant HPV vaccination is associated with a reduced risk of CIN recurrence, although there are limited data regarding its role in other HPV-related diseases. Further research is warranted to shed more light on the role of HPV vaccination as adjuvant therapy after primary treatment.

Published
2022
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8. Internet and social media use among patients with colorectal diseases (ISMAEL): a nationwide survey

Author

Sturiale, A, Pata, F, De Simone, V, Pellino, G, Campenni, P, Moggia, E, Manigrasso, M, Milone, M, Rizzo, G, Morganti, R, Martellucci, J, Gallo, G, ISMAEL Working Group (Luca Turati, Fabio, Marino, Elia, Poiasina, Pierluigi, Lobascio, Luca, Cardinali, Marco Enrico Mario Maino, Isacco, Maretto, Filippo La Torre, Paolo, Stella, Antonino, Spinelli, Giovanni, Milito, Andrea, Bondurri, Morelli, Luca, Massimo, Buonfantino, Nicolò, Tamini, Maria Carmela Giuffrida, Gianluigi, Moretto, Donato Francesco Altomare, Giuseppe, Sammarco, Paola De Nardi, Stefano, Berti, Claudio, Coco, Renato, Pietroletti, Gianfranco, Cocorullo, Paolo, Tonello, Giuseppe, Candilio, Patrizia, Marsanic, Giovanni De Palma, Iacopo, Giani, Massimiliano, Mistrangelo, Jacopo, Martellucci, Gaetano, Luglio, Marco, Frascio, Paolo, Delrio, Mario, Trompetto, Antonella, Chessa, Giovanni, Landolfo, Gabriele, Naldini, Valentina, Rampulla, Antonio, Costanzo, Fabrizio, Aquilino, Nicola, Chetta, Michele, Marini, Gabor, Panyor, Marina, Minafra, Rita La Forgia, Angelica, Reggiani, Angelo Antonio Carrieri, Guglielmo Niccolò Pozzi, Riccardo, Cirelli, Andrea, Barina, Giulia, Becherucci, Ilaria, Clementi, Paolo, Boati, Francesco, Ferrara, Paola, Campennì, Francesca Di Candido, Giorgio, Lisi, Maria, Lemma, Anna, Maffioli, DI FRANCO, Gregorio, Eleonora, Guaitoli, Marco, Totis, Maria Francesca Chiappetta, Paola, Salusso, Lorenzo, Bono, Matilde, Bacchion, Harmony, Impellizzeri, Arcangelo, Picciariello, Vincenzo, Papagni, Matteo, Papandrea, Vincenzo, Tiesi, Giusy, Talamo, Mikaela, Imperatore, Federisca, D'Ascanio, Nicola, Falco, Tommaso, Fontana, Silvia, Cornaglia, Giovanni, Bertolotti, Cristiano, Giardiello, Giovanni, Martino, Marco, Calussi, Zalla, Tiku, Federica Di Marco, Andrea, Muratore, Veronica, Iacopini, Alessio, Minuzzo, Marco, Milone, Michele, Manigrasso, Diego, Sasia, Valentina, Testa, Gianluca, Pagano, Roberto, Peltrini, Andrea, Razzore, Paola, Batistotti, Daniela, Rega, Andrea Fares Bucci, Michela, Campanelli, Roberta, Tutino, Eugenia, Sinatti, Lucia, Morganti, Elia, Smerieri, Alessandro, Sturiale, Bernandina, Fabiani), ISMAEL working group Sturiale, A., Pata, F., De Simone, V., Pellino, G., Campenni, P., Moggia, E., Manigrasso, M., Milone, M., Rizzo, G., Morganti, R., Martellucci, J., Luca Turati, Gallo G., Fabio, Marino, Elia, Poiasina, Pierluigi, Lobascio, Luca, Cardinali, Marco Enrico Mario Maino, Isacco, Maretto, Filippo La Torre, Paolo, Stella, Antonino, Spinelli, Giovanni, Milito, Andrea, Bondurri, Luca, Morelli, Massimo, Buonfantino, Nicolò, Tamini, Maria Carmela Giuffrida, Gianluigi, Moretto, Donato Francesco Altomare, Giuseppe, Sammarco, Paola De Nardi, Stefano, Berti, Claudio, Coco, Renato, Pietroletti, Gianfranco, Cocorullo, Paolo, Tonello, Giuseppe, Candilio, Patrizia, Marsanic, Giovanni De Palma, Iacopo, Giani, Massimiliano, Mistrangelo, Jacopo, Martellucci, Luglio, Gaetano, Marco, Frascio, Paolo, Delrio, Mario, Trompetto, Antonella, Chessa, Giovanni, Landolfo, Gabriele, Naldini, Valentina, Rampulla, Antonio, Costanzo, Fabrizio, Aquilino, Nicola, Chetta, Michele, Marini, Gabor, Panyor, Marina, Minafra, Rita La Forgia, Angelica, Reggiani, Angelo Antonio Carrieri, Guglielmo Niccolò Pozzi, Riccardo, Cirelli, Andrea, Barina, Giulia, Becherucci, Ilaria, Clementi, Paolo, Boati, Francesco, Ferrara, Paola, Campennì, Francesca Di Candido, Giorgio, Lisi, Maria, Lemma, Anna, Maffioli, Gregorio Di Franco, Eleonora, Guaitoli, Marco, Toti, Maria Francesca Chiappetta, Paola, Salusso, Lorenzo, Bono, Matilde, Bacchion, Harmony, Impellizzeri, Arcangelo, Picciariello, Vincenzo, Papagni, Matteo, Papandrea, Vincenzo, Tiesi, Giusy, Talamo, Mikaela, Imperatore, Federisca, D'Ascanio, Nicola, Falco, Tommaso, Fontana, Silvia, Cornaglia, Giovanni, Bertolotti, Cristiano, Giardiello, Giovanni, Martino, Marco, Calussi, Zalla, Tiku, Federica Di Marco, Andrea, Muratore, Veronica, Iacopini, Alessio, Minuzzo, Marco, Milone, Michele, Manigrasso, Diego, Sasia, Valentina, Testa, Gianluca, Pagano, Peltrini, Roberto, Andrea, Razzore, Paola, Batistotti, Daniela, Rega, Andrea Fares Bucci, Michela, Campanelli, Roberta, Tutino, Eugenia, Sinatti, Lucia, Morganti, Elia, Smerieri, Alessandro, Sturiale, Bernandina, Fabiani, Sturiale, A., and Gallo, G.

Subjects
medicine.medical_specialty, colorectal patient, Anorectal disease, PPI, social media, Patient engagement, Disease, Colorectal Neoplasm, Nationwide survey, proctology, 03 medical and health sciences, 0302 clinical medicine, colorectal patients, colorectal diseases, internet, patient engagement, Internet, Surveys and Questionnaires, Health care, medicine, Humans, Surveys and Questionnaire, Social media, colorectal disease, Surgeons, Physician-Patient Relations, Physician-Patient Relation, business.industry, Gastroenterology, 030220 oncology & carcinogenesis, Family medicine, Population study, 030211 gastroenterology & hepatology, The Internet, Colorectal Neoplasms, business, Human
Abstract

Aim: Social media are used daily by both healthcare workers and patients. Online platforms have the potential to provide patients with useful information, increase their engagement and potentially revolutionize the patient–physician relationship. This survey aimed to evaluate the impact of the Internet and social media (I&SM) on patients affected by colorectal and proctological diseases to define a pathway to develop an evidence-based communications strategy. Method: A 31-item anonymous electronic questionnaire was designed. It consisted of different sections concerning demographics and education, reason for the visit, knowledge of the diseases, frequency of I&SM use and patients' opinions about physicians' websites. Results: Over a 5-month period, 37 centres and 105 surgeons took part in the survey, and a total of 5800 patients enrolled. Approximately half of them reported using the Internet daily, and 74.6% of the study population used it at least once per week. There was a correlation (P&nbsp

Published
2020

9. Microhematuria at Point of Care

Author

Federica Zerini, Elio Magistrelli, Simone Magistri, Barbara Vignati, Marco Maria Paganuzzi, Luca Spiro Santovito, Andrea Gregori, Lorenzo Casati, Maurizio Gallieni, Martina Tedesco, Pietro Monticelli, Lorenzo Ticini, Martina Volontè, Marco Elli, Matteo Gambaretti, Silvia Cozzi, Davide Vergallito, Federica Civita, and Ilaria Clementi

Subjects
medicine.medical_specialty, Bladder cancer, urogenital system, business.industry, Urology, Urine, Dipstick, Kidney, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, urologic and male genital diseases, medicine.disease, medicine.icd_9_cm_classification, female genital diseases and pregnancy complications, Urinary sediment, Diagnosis, Medicine, Microhematuria, Microscopic hematuria, business, Point of care
Abstract

The case of a 35-year-old man presenting microscopic hematuria allows the following topics to be examined in depth: 1. How is hematuria defined and classified? 2. What are the causes of hematuria? 3. Hematuria is an important sign for the diagnosis of cancer of the urinary system. What are the risk factors for bladder carcinoma? 4. What is the role of the urinary dipstick test in the diagnosis of hematuria? 5. What is the role of the examination of urine sediment in the diagnosis of hematuria? 6. Once microscopic hematuria is confirmed, how can we proceed to reach a final diagnosis?

Published
2017

10. Perforated jejuneal diverticulosis. Case report and review of literature

Author

Marco, Assenza, Gabriele, Ricci, Angelo, Antoniozzi, Ilaria, Clementi, Luigi, Simonelli, and Claudio, Modini

Subjects
Male, Diverticulum, Intestinal Perforation, Humans, Jejunal Diseases, Aged
Abstract

Acquired (non-Meckel's) jejunoileal diverticulosis is an uncommon disease, generally characterised by vague and unspecific symptoms. This rare condition is mainly expressed as acute complications: gastrointestinal haemorrhage, mechanic obstruction of the small intestine or perforated diverticulum, requiring urgent surgical intervention. The authors report a case of this unusual clinical occurrence characterized by a picture of abdominal pain due to perforation of jejuneal diverticulum. The final etiological diagnosis was possible only during surgery.

Published
2007

11. Iatrogenic intramural hematoma of the duodenum caused by endoscopic therapy of bleeding peptic ulcer. A case report

Author

Marco, Assenza, Gabriele, Ricci, Angelo, Antoniozzi, Ilaria, Clementi, Flavia, Ciccapone, Luigi, Simonelli, and Claudio, Modini

Subjects
Aged, 80 and over, Male, Hematoma, Peptic Ulcer Hemorrhage, Treatment Outcome, Duodenal Ulcer, Hemostasis, Endoscopic, Humans
Abstract

The authors report a case of intestinal obstruction resulting from a duodenal intramural hematoma after therapeutic upper digestive endoscopy with injection therapy. Intramural duodenal hematomas are rare clinical entities, mostly caused by blunt traumas. They may also, more rarely, be due to complications of peptic duodenal ulcers, or be the iatrogenic result of an endoscopic biopsy or placement of a percutaneous endoscopic gastrostomy catheter. It has recently become obvious that surgery is not necessary in most patients with duodenal hematomas. The treatment of choice for cases of intramural duodenal hematomas is of a conservative kind. Today we can employ minimally invasive diagnostic and therapeutic techniques for the percutaneous or laparoscopic evacuation of the hematoma, which seem to guarantee optimal results, compared to the high morbidity rate associated with laparatomy evacuation.

Published
2007

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