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214 results on '"Ikeda, Shigeo"'

2. Using the supercharge technique to additionally revascularize the gastric tube after a subtotal esophagectomy for esophageal cancer

Author

Yoshimi, Fuyo, Asato, Yuji, Ikeda, Shigeo, Okamoto, Kojun, Komuro, Yasuhiro, Imura, Johji, and Itabashi, Masayuki

Subjects
Esophageal cancer -- Methods, Health
Abstract

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.amjsurg.2005.04.019 Byline: Fuyo Yoshimi (a), Yuji Asato (a), Shigeo Ikeda (a), Kojun Okamoto (a), Yasuhiro Komuro (a), Johji Imura (b), Masayuki Itabashi (b) Keywords: Subtotal esophagectomy; Esophagogastric anastomosis; Supercharge technique; Vascular anastomosis Abstract: Maintaining sufficient blood flow to the gastric tube after a subtotal esophagectomy for esophageal cancer is crucial for decreasing esophagogastric anastomotic leakage. Author Affiliation: (a) Department of Surgery, Ibaraki Prefectural Central Hospital and Cancer Center, 6528 Koibuchi, Tomobe-machi, Ibaraki 309-1793, Japan (b) Department of Pathology, Ibaraki Prefectural Central Hospital and Cancer Center, Ibaraki, Japan Article History: Received 15 November 2004; Revised 7 April 2005

Published
2006

28. [An experimental study on the effects of postburn dietary supplementation of enhanced nutrients]

Author

Shu-liang, Lu, Shu-wen, Jin, Jian, Zhang, Ikeda, Shigeo, Saito, Hideaki, Zhen-jiang, Liao, and Ji-xiang, Shi

Subjects
Male, Rats, Sprague-Dawley, Random Allocation, Wound Healing, Enteral Nutrition, Linolenic Acids, Glutamine, Dietary Supplements, Animals, Female, Arginine, Burns, Rats
Abstract

To evaluate the effects of postburn dietary supplementation of arginine (Arg), omega-3 polyunsaturated fatty acid (omega-3PUFA) and glutamine (Glu) on the metabolism, immunology and wound healing in scalded rats.Thirty Sprague-Dawley (SD) rats inflicted with 30% total body surface area deep partial thickness scald on the back after the gastrostomy catheter was placed were employed as the model. The rats were randomly divided into A and B groups, and all of them received continuous isonitrogenous (25% protein, 12% fat, 63% carbohydrate), isocaloric (175 kcal/kg/day), and isovolemic intragastric tube feedings. The contents of Arg, omega-3PUFA, Glu in the dietary of B group were enriched. The parameters were measured on the 10th day after injury, including the response of spleen cells to ConA, the plasma levels of PGE(2), IL-2, albumin, transferrin, glucagons, cortisol in blood, the urinary content of vanillylmandelic acid (VAM) in 24-hour urine, the content of hydroxyproline, the ratio of type I to type III collagen in burn wounds, and the nitrogen content in the liver and in the jejunal mucosa, as well as the weight changes, skin delayed hypersensitivity test, and wound healing time.It was revealed that the serum level of albumin, the nitrogen content in the liver and in the jejunal mucosa were obviously higher in B than those in A group. At the same time, there was no statistical difference in the plasma levels of cortisol and glucagons and urinary content of VAM between the two groups, nor in body weight changes. Meanwhile, the response of spleen cells to ConA and the skin delayed hypersensitivity induced by DNFB 14 days after injury in group B were also enhanced compared with those in group A. Although the expression of PGE2 from peritoneal macrophages was lower, the content of hydroxyproline from burn wounds in group B was significantly higher than that in group A, and the ratio of type l to type III collagen in group B was significantly lower than that in group A. Compared with group A, the wound healing time in group B was significantly shortened (P0.05).The low-fat and high-protein feeding diet with enriched arginine, omega-3 PUFA, glutamine could benefit the nutritional status after burn injury, thus improve the immunological function and promote wound healing.

Published
2003

29. Glutamine and bombesin do not regulate gut associated lymphoid tissue via mucosal addressin cell adhesion molecule-1

Author

Ikeda, Shigeo, Zarzaur, Ben L., Johnson, Cheryl D., Sacks, Gordon, and Kudsk, Kenneth A.

Subjects
Cell adhesion molecules -- Health aspects, Parenteral feeding -- Physiological aspects, Intestinal mucosa -- Physiological aspects, Food/cooking/nutrition, Health
Abstract

Introduction: Lack of enteral feeding reduces gut-associated lymphoid tissue (GALT) cell numbers, intestinal and respiratory IgA, and Peyer's patch (PP) mucosal addressin cell adhesion molecule-1 (MAdCAM-1) expression. MAdCAM-1 is the principal marker directing T and B cells into the PP and the GALT. Blocking of MAdCAM-1 produces PP atrophy similar to IV-TPN. Aim: Since both bombesin (BBS) and glutamine (GLN) reverse IV-TPN induced changes in GALT and mucosal immunity, this work examines their effects on PP MAdCAM-1 expression. Methods: Exp 1: 28 mice were randomized to get Chow (n=8), TPN (n=9), or isonitrogenous 2% GLN-TPN (n=11) for 5 days. MAdCAM-1 expression in PP, intestine, and spleen was quantified using [sup.125]I-MECA 367 (anti-MAdCAM-1) and [sup.131]I nonspecific monoclonal antibodies (mAb). Exp. 2: Using the dual mAb technique, MAdCAM-1 expression was measured in 32 mice randomized to 5 days of Chow (n=11), TPN (n=10), or TPN-BBS (15 pg/kg IV TID, n=11). Data (mean [+ or -] SEM of pg mAb/tissue) was analyzed by ANOVA. Results: Exp 1: PP MAdCAM-1 expression decreased with TPN (0.026 [+ or -] .002) vs Chow (0.048 [+ or -] .009) (p

Published
2002

50. Effects of growth hormone and insulin-like growth factor I on opsonin receptor expression on local and systemic phagocytes in a lethal peritonitis model

Author

Inoue, Tomomi, primary, Saito, Hideaki, additional, Tsuno, Nelson, additional, Fukatsu, Kazuhiko, additional, Lin, Ming-Tsan, additional, Inaba, Tsuyoshi, additional, Han, Ilsoo, additional, Furukawa, Satoshi, additional, Ikeda, Shigeo, additional, Matsuda, Takeaki, additional, and Muto, Tetsuichiro, additional

Published
1998
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