268 results on '"Ikeda, Joh-E"'
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2. Genetic background and gender effects on gross phenotypes in congenic lines of ALS2/alsin-deficient mice
3. A dopamine receptor antagonist L-745,870 suppresses microglia activation in spinal cord and mitigates the progression in ALS model mice
4. Abstracts from the ASENT 2007 Annual Meeting March 5–8, 2007
5. The Rab5 Activator ALS2/alsin Acts as a Novel Rac1 Effector through Rac1-activated Endocytosis
6. ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics
7. Molecular and cellular function of ALS2/alsin: Implication of membrane dynamics in neuronal development and degeneration
8. Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene
9. Production of transgenic miniature pigs by pronuclear microinjection
10. A novel small molecule, N-(4-(2-pyridyl)(1,3-thiazol-2-yl))-2-(2,4,6-trimethylphenoxy) acetamide, selectively protects against oxidative stress-induced cell death by activating the Nrf2–ARE pathway: Therapeutic implications for ALS
11. Genomic organization of the human caspase-9 gene on Chromosome 1p36.1-p36.3
12. Purification and Functional Analyses of ALS2 and its Homologue
13. Molecular characterization and cytological mapping of a non-repetitive DNA sequence region from the W chromosome of chicken and its use as a universal probe for sexing Carinatae birds
14. Characterization of DNA sequences constituting the terminal heterochromatin of the chicken Z chromosome
15. A recombination event occurring within two complex 5q13.1 microsatellite repeat polymorphisms suggests a telomeric mapping of spinal muscular atrophy
16. Identification of the origin of double minutes in normal human cells by laser-based chromosome microdissection approach
17. Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking
18. A linkage study with DNA markers (D4S95, D4S115, and D4S111) in Japanese Huntington disease families
19. Homo-oligomerization of ALS2 through Its Unique Carboxyl-terminal Regions Is Essential for the ALS2-associated Rab5 Guanine Nucleotide Exchange Activity and Its Regulatory Function on Endosome Trafficking
20. A Dopamine D4 Receptor Antagonist Attenuates Ischemia-Induced Neuronal Cell Damage via Upregulation of Neuronal Apoptosis Inhibitory Protein
21. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes
22. Novel Nuclear Shuttle Proteins, HDBP1 and HDBP2, Bind to Neuronal Cell-specific cis-Regulatory Element in the Promoter for the Human Huntington's Disease Gene
23. Inhibition of myogenesis in transgenic mice expressing the human DMPK 3′-UTR
24. ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics
25. Studies on DNA markers (D4S10 and D4S43/S127) genetically linked to Huntington's disease in Japanese families
26. Linear plasmid DNAs of the plant pathogenic fungus Rhizoctonia solani with unique terminal structures
27. HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis
28. Inhibition of Cyclin-Dependent Kinases Improves CA1 Neuronal Survival and Behavioral Performance After Global Ischemia in the Rat
29. Functional human NAIP promoter transcription regulatory elements for the NAIP and ΨNAIP genes
30. The structures of integration sites in transgenic rice
31. Cloning and Characterization of Three Novel Genes, ALS2CR1, ALS2CR2, and ALS2CR3, in the Juvenile Amyotrophic Lateral Sclerosis (ALS2) Critical Region at Chromosome 2q33–q34: Candidate Genes for ALS2
32. Identification and Characterization of the Miniature Pig Huntington's Disease Gene Homolog: Evidence for Conservation and Polymorphism in the CAG Triplet Repeat
33. The RS447 Human Megasatellite Tandem Repetitive Sequence Encodes a Novel Deubiquitinating Enzyme with a Functional Promoter
34. Neuronal apoptosis inhibitory protein is implicated in amyotrophic lateral sclerosis symptoms
35. Identification of Two Distinct Transcripts for the Neuronal Apoptosis Inhibitory Protein Gene
36. A novel function of N-linked glycoproteins, alpha-2-HS-glycoprotein and hemopexin: Implications for small molecule compound-mediated neuroprotection
37. Cyclin-dependent kinases as a therapeutic target for stroke
38. Erratum
39. 小児期の近位型脊髄性筋萎縮症の臨床像と分子遺伝学的診断
40. Defective relocalization of ALS2/alsin missense mutants to Rac1-induced macropinosomes accounts for loss of their cellular function and leads to disturbed amphisome formation
41. A Novel Acylaminoimidazole Derivative, WN1316, Alleviates Disease Progression via Suppression of Glial Inflammation in ALS Mouse Model
42. Bromocriptine Mesylate Attenuates Amyotrophic Lateral Sclerosis: A Phase 2a, Randomized, Double-Blind, Placebo-Controlled Research in Japanese Patients.
43. ALS2/alsin deficiency in neurons leads to mild defects in macropinocytosis and axonal growth
44. Loss of ALS2/Alsin Exacerbates Motor Dysfunction in a SOD1H46R-Expressing Mouse ALS Model by Disturbing Endolysosomal Trafficking
45. Disturbance of endolysosomal protein degradation underlies the pathogenesis of ALS2-linked motor neuron diseases
46. The therapeutic agent NDDPX08 promotes sustainable motor performance and extends a post-onset survival interval in an ALS mouse model
47. Megasatellite DNA
48. HFM1, the human homologue of yeast Mer3, encodes a putative DNA helicase expressed specifically in germ-line cells
49. Morphodynamics of ovarian follicles during oogenesis in mice
50. Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking
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