Search

Your search keyword '"Iga, Masatoshi"' showing total 44 results
Start Over Author "Iga, Masatoshi"
44 results on '"Iga, Masatoshi"'

4. Unique Material Properties of Bombyx moriSilk Fiber Incorporated with 3-Azidotyrosine

Author

Teramoto, Hidetoshi, Kojima, Katsura, Iga, Masatoshi, and Yoshioka, Taiyo

Abstract

Silk fiber produced by the silkworm Bombyx moriis a nature-derived proteinous fiber with excellent mechanical strength and broad biocompatibility. To alter its material properties and make it more suitable for textile, biomedical, and electronics applications, chemical modifications and genetic engineering methods have been extensively studied. Here, we report that the translational incorporation of a synthetic amino acid, 3-azidotyrosine (3-AzTyr), into B. morisilk fiber can improve its material properties. Such an incorporation considerably increased the fiber’s mechanical strength and remarkably changed its solubility, whereas its crystalline hierarchical structure was not perturbed, as shown by X-ray analyses. These changes were probably caused by the intra- and/or intermolecular crosslinkings involving the azido group of 3-AzTyr during the degumming process to remove a coating protein. These findings indicate that the incorporation of synthetic amino acids could be an efficient method to improve the properties of silk-based materials.

Published
2023
Full Text
View/download PDF

6. The genome of Tetranychus urticae reveals herbivorous pest adaptations

Author

Grbić, Miodrag, Van Leeuwen, Thomas, Clark, Richard M., Rombauts, Stephane, Rouzé, Pierre, Grbić, Vojislava, Osborne, Edward J., Dermauw, Wannes, Thi Ngoc, Phuong Cao, Ortego, Félix, Hernández-Crespo, Pedro, Diaz, Isabel, Martinez, Manuel, Navajas, Maria, Sucena, Élio, Magalhães, Sara, Nagy, Lisa, Pace, Ryan M., Djuranović, Sergej, Smagghe, Guy, Iga, Masatoshi, Christiaens, Olivier, Veenstra, Jan A., Ewer, John, Villalobos, Rodrigo Mancilla, Hutter, Jeffrey L., Hudson, Stephen D., Velez, Marisela, Yi, Soojin V., Zeng, Jia, Pires-daSilva, Andre, Roch, Fernando, Cazaux, Marc, Navarro, Marie, Zhurov, Vladimir, Acevedo, Gustavo, Bjelica, Anica, Fawcett, Jeffrey A., Bonnet, Eric, Martens, Cindy, Baele, Guy, Wissler, Lothar, Sanchez-Rodriguez, Aminael, Tirry, Luc, Blais, Catherine, Demeestere, Kristof, Henz, Stefan R., Gregory, Ryan T., Mathieu, Johannes, Verdon, Lou, Farinelli, Laurent, Schmutz, Jeremy, Lindquist, Erika, Feyereisen, René, and Van de Peer, Yves

Published
2011
Full Text
View/download PDF

13. Dual Roles of Glutathione in Ecdysone Biosynthesis and Antioxidant Function During Larval Development in Drosophila

Author

Enya, Sora, primary, Yamamoto, Chikana, additional, Mizuno, Hajime, additional, Esaki, Tsuyoshi, additional, Lin, Hsin-Kuang, additional, Iga, Masatoshi, additional, Morohashi, Kana, additional, Hirano, Yota, additional, Kataoka, Hiroshi, additional, Masujima, Tsutomu, additional, Shimada-Niwa, Yuko, additional, and Niwa, Ryusuke, additional

Published
2017
Full Text
View/download PDF

21. Cooperative Control of Ecdysone Biosynthesis in Drosophilaby Transcription Factors Séance, Ouija Board, and Molting Defective

Author

Uryu, Outa, Ou, Qiuxiang, Komura-Kawa, Tatsuya, Kamiyama, Takumi, Iga, Masatoshi, Syrzycka, Monika, Hirota, Keiko, Kataoka, Hiroshi, Honda, Barry M, King-Jones, Kirst, and Niwa, Ryusuke

Abstract

Ecdysteroids are steroid hormones that control many aspects of development and physiology. During larval development, ecdysone is synthesized in an endocrine organ called the prothoracic gland through a series of ecdysteroidogenic enzymes encoded by the Halloween genes. The expression of the Halloween genes is highly restricted and dynamic, indicating that their spatiotemporal regulation is mediated by their tight transcriptional control. In this study, we report that three zinc finger-associated domain (ZAD)-C2H2zinc finger transcription factors—Séance (Séan), Ouija board (Ouib), and Molting defective (Mld)—cooperatively control ecdysone biosynthesis in the fruit fly Drosophila melanogaster. Séan and Ouib act in cooperation with Mld to positively regulate the transcription of neverlandand spookier, respectively, two Halloween genes. Remarkably, loss-of-function mutations in séan, ouib, or mldcan be rescued by the expression of neverland, spookier, or both, respectively. These results suggest that the three transcription factors have distinct roles in coordinating the expression of just two genes in Drosophila. Given that neverlandand spookierare located in constitutive heterochromatin, Séan, Ouib, and Mld represent the first example of a transcription factor subset that regulates genes located in constitutive heterochromatin.

Published
2018
Full Text
View/download PDF

23. RNA interference in Lepidoptera : An overview of successful and unsuccessful studies and implications for experimental design

Author

Terenius, Olle, Papanicolaou, Alexie, Garbutt, Jennie S., Eleftherianos, Ioannis, Huvenne, Hanneke, Kanginakudru, Sriramana, Albrechtsen, Merete, An, Chunju, Aymeric, Jean-Luc, Barthel, Andrea, Bebas, Piotr, Bitra, Kavita, Bravo, Alejandra, Chevalier, François, Collinge, Derek P., Crava, Cristina M., de Maagd, Ruud A., Duvic, Bernard, Erlandson, Martin, Faye, Ingrid, Felföldi, Gabriella, Fujiwara, Haruhiko, Futahashi, Ryo, Gandhe, Archana S., Gatehouse, Heather S., Gatehouse, Laurence N., Giebultowicz, Jadwiga M., Gómez, Isabel, Grimmelikhuijzen, Cornelis J. P., Groot, Astrid T., Hauser, Frank, Heckel, David G., Hegedus, Dwayne D., Hrycaj, Steven, Huang, Lihua, Hull, J. Joe, Iatrou, Kostas, Iga, Masatoshi, Kanost, Michael R., Kotwica, Joanna, Li, Changyou, Li, Jianghong, Liu, Jisheng, Lundmark, Magnus, Matsumoto, Shogo, Meyering-Vos, Martina, Millichap, Peter J., Monteiro, Antónia, Mrinal, Nirotpal, Niimi, Teruyuki, Nowara, Daniela, Ohnishi, Atsushi, Oostra, Vicencio, Ozaki, Katsuhisa, Papakonstantinou, Maria, Popadic, Aleksandar, Rajam, Manchikatla V., Saenko, Suzanne, Simpson, Robert M., Soberón, Mario, Strand, Michael R., Tomita, Shuichiro, Toprak, Umut, Wang, Ping, Wee, Choon Wei, Whyard, Steven, Zhang, Wenqing, Nagaraju, Javaregowda, Ffrench-Constant, Richard H., Herrero, Salvador, Gordon, Karl, Swevers, Luc, Smagghe, Guy, Terenius, Olle, Papanicolaou, Alexie, Garbutt, Jennie S., Eleftherianos, Ioannis, Huvenne, Hanneke, Kanginakudru, Sriramana, Albrechtsen, Merete, An, Chunju, Aymeric, Jean-Luc, Barthel, Andrea, Bebas, Piotr, Bitra, Kavita, Bravo, Alejandra, Chevalier, François, Collinge, Derek P., Crava, Cristina M., de Maagd, Ruud A., Duvic, Bernard, Erlandson, Martin, Faye, Ingrid, Felföldi, Gabriella, Fujiwara, Haruhiko, Futahashi, Ryo, Gandhe, Archana S., Gatehouse, Heather S., Gatehouse, Laurence N., Giebultowicz, Jadwiga M., Gómez, Isabel, Grimmelikhuijzen, Cornelis J. P., Groot, Astrid T., Hauser, Frank, Heckel, David G., Hegedus, Dwayne D., Hrycaj, Steven, Huang, Lihua, Hull, J. Joe, Iatrou, Kostas, Iga, Masatoshi, Kanost, Michael R., Kotwica, Joanna, Li, Changyou, Li, Jianghong, Liu, Jisheng, Lundmark, Magnus, Matsumoto, Shogo, Meyering-Vos, Martina, Millichap, Peter J., Monteiro, Antónia, Mrinal, Nirotpal, Niimi, Teruyuki, Nowara, Daniela, Ohnishi, Atsushi, Oostra, Vicencio, Ozaki, Katsuhisa, Papakonstantinou, Maria, Popadic, Aleksandar, Rajam, Manchikatla V., Saenko, Suzanne, Simpson, Robert M., Soberón, Mario, Strand, Michael R., Tomita, Shuichiro, Toprak, Umut, Wang, Ping, Wee, Choon Wei, Whyard, Steven, Zhang, Wenqing, Nagaraju, Javaregowda, Ffrench-Constant, Richard H., Herrero, Salvador, Gordon, Karl, Swevers, Luc, and Smagghe, Guy

Abstract

Gene silencing through RNA interference (RNAi) has revolutionized the study of gene function, particularly in non-model insects. However, in Lepidoptera (moths and butterflies) RNAi has many times proven to be difficult to achieve. Most of the negative results have been anecdotal and the positive experiments have not been collected in such a way that they are possible to analyze. In this review, we have collected detailed data from more than 150 experiments including all to date published and many unpublished experiments. Despite a large variation in the data, trends that are found are that RNAi is particularly successful in the family Saturniidae and in genes involved in immunity. On the contrary, gene expression in epidermal tissues seems to be most difficult to silence. In addition, gene silencing by feeding dsRNA requires high concentrations for success. Possible causes for the variability of success in RNAi experiments in Lepidoptera are discussed. The review also points to a need to further investigate the mechanism of RNAi in lepidopteran insects and its possible connection to the innate immune response. Our general understanding of RNAi in Lepidoptera will be further aided in the future as our public database at http://insectacentral.org/RNAi will continue to gather information on RNAi experiments.

Published
2011
Full Text
View/download PDF

24. Genome Sequence of the Pea Aphid Acyrthosiphon pisum

Author

Richards, Stephen, Gibbs, Richard A., Gerardo, Nicole M., Moran, Nancy, Nakabachi, Atsushi, Stern, David, Tagu, Denis, Wilson, Alex C. C., Muzny, Donna, Kovar, Christie, Cree, Andy, Chacko, Joseph, Chandrabose, Mimi N., Dao, Marvin Diep, Dinh, Huyen H., Gabisi, Ramatu Ayiesha, Hines, Sandra, Hume, Jennifer, Jhangian, Shalini N., Joshi, Vandita, Lewis, Lora R., Liu, Yih-shin, Lopez, John, Morgan, Margaret B., Nguyen, Ngoc Bich, Okwuonu, Geoffrey O., Ruiz, San Juana, Santibanez, Jireh, Wright, Rita A., Fowler, Gerald R., Hitchens, Matthew E., Lozado, Ryan J., Moen, Charles, Steffen, David, Warren, James T., Zhang, Jingkun, Nazareth, Lynne V., Chavez, Dean, Davis, Clay, Lee, Sandra L., Patel, Bella Mayurkumar, Pu, Ling-Ling, Bell, Stephanie N., Johnson, Angela Jolivet, Vattathil, Selina, Williams, Rex L., Jr., Shigenobu, Shuji, Dang, Phat M., Morioka, Mizue, Fukatsu, Takema, Kudo, Toshiaki, Miyagishima, Shin-ya, Jiang, Huaiyang, Worley, Kim C., Legeai, Fabrice, Gauthier, Jean-Pierre, Collin, Olivier, Zhang, Lan, Chen, Hsiu-Chuan, Ermolaeva, Olga, Hlavina, Wratko, Kapustin, Yuri, Kiryutin, Boris, Kitts, Paul, Maglott, Donna, Murphy, Terence, Pruitt, Kim, Sapojnikov, Victor, Souvorov, Alexandre, Thibaud-Nissen, Francoise, Camara, Francisco, Guigo, Roderic, Stanke, Mario, Solovyev, Victor, Kosarev, Peter, Gilbert, Don, Gabaldon, Toni, Huerta-Cepas, Jaime, Marcet-Houben, Marina, Pignatelli, Miguel, Moya, Andres, Rispe, Claude, Ollivier, Morgane, Quesneville, Hadi, Permal, Emmanuelle, Llorens, Carlos, Futami, Ricardo, Hedges, Dale, Robertson, Hugh M., Alioto, Tyler, Mariotti, Marco, Nikoh, Naruo, McCutcheon, John P., Burke, Gaelen, Kamins, Alexandra, Latorre, Amparo, Moran, Nancy A., Ashton, Peter, Calevro, Federica, Charles, Hubert, Colella, Stefano, Douglas, Angela, Jander, Georg, Jones, Derek H., Febvay, Gerard, Kamphuis, Lars G., Kushlan, Philip F., Macdonald, Sandy, Ramsey, John, Schwartz, Julia, Seah, Stuart, Thomas, Gavin, Vellozo, Augusto, Cass, Bodil, Degnan, Patrick, Hurwitz, Bonnie, Leonardo, Teresa, Koga, Ryuichi, Altincicek, Boran, Anselme, Caroline, Atamian, Hagop, Barribeau, Seth M., de Vos, Martin, Duncan, Elizabeth J., Evans, Jay, Ghanim, Murad, Heddi, Abdelaziz, Kaloshian, Isgouhi, Vincent-Monegat, Carole, Parker, Ben J., Perez-Brocal, Vicente, Rahbe, Yvan, Spragg, Chelsea J., Tamames, Javier, Tamarit, Daniel, Tamborindeguy, Cecilia, Vilcinskas, Andreas, Bickel, Ryan D., Brisson, Jennifer A., Butts, Thomas, Chang, Chun-che, Christiaens, Olivier, Davis, Gregory K., Duncan, Elizabeth, Ferrier, David, Iga, Masatoshi, Janssen, Ralf, Lu, Hsiao-Ling, McGregor, Alistair, Miura, Toru, Smagghe, Guy, Smith, James, van der Zee, Maurijn, Velarde, Rodrigo, Wilson, Megan, Dearden, Peter, Edwards, Owain R., Gordon, Karl, Hilgarth, Roland S., Rider, Stanley Dean, Jr., Srinivasan, Dayalan, Walsh, Thomas K., Ishikawa, Asano, Jaubert-Possamai, Stephanie, Fenton, Brian, Huang, Wenting, Rizk, Guillaume, Lavenier, Dominique, Nicolas, Jacques, Smadja, Carole, Zhou, Jing-Jiang, Vieira, Filipe G., He, Xiao-Li, Liu, Renhu, Rozas, Julio, Field, Linda M., Ashton, Peter D., Campbell, Peter, Carolan, James C., Douglas, Angela E., Fitzroy, Carol I. J., Reardon, Karen T., Reeck, Gerald R., Singh, Karam, Wilkinson, Thomas L., Huybrechts, Jurgen, Abdel-latief, Mohatmed, Robichon, Alain, Veenstra, Jan A., Hauser, Frank, Cazzamali, Giuseppe, Schneider, Martina, Williamson, Michael, Stafflinger, Elisabeth, Hansen, Karina K., Grimmelikhuijzen, Cornelis J. P., Price, Daniel R. G., Caillaud, Marina, van Fleet, Eric, Ren, Qinghu, Gatehouse, John A., Brault, Veronique, Monsion, Baptiste, Diaz, Jason, Hunnicutt, Laura, Ju, Ho-Jong, Pechuan, Ximo, Aguilar, Jose, Cortes, Teresa, Ortiz-Rivas, Benjamin, Martinez-Torres, David, Dombrovsky, Aviv, Dale, Richard P., Davies, T. G. Emyr, Williamson, Martin S., Jones, Andrew, Sattelle, David, Williamson, Sally, Wolstenholme, Adrian, Cottret, Ludovic, Sagot, Marie France, Heckel, David G., Hunter, Wayne, Richards, Stephen, Gibbs, Richard A., Gerardo, Nicole M., Moran, Nancy, Nakabachi, Atsushi, Stern, David, Tagu, Denis, Wilson, Alex C. C., Muzny, Donna, Kovar, Christie, Cree, Andy, Chacko, Joseph, Chandrabose, Mimi N., Dao, Marvin Diep, Dinh, Huyen H., Gabisi, Ramatu Ayiesha, Hines, Sandra, Hume, Jennifer, Jhangian, Shalini N., Joshi, Vandita, Lewis, Lora R., Liu, Yih-shin, Lopez, John, Morgan, Margaret B., Nguyen, Ngoc Bich, Okwuonu, Geoffrey O., Ruiz, San Juana, Santibanez, Jireh, Wright, Rita A., Fowler, Gerald R., Hitchens, Matthew E., Lozado, Ryan J., Moen, Charles, Steffen, David, Warren, James T., Zhang, Jingkun, Nazareth, Lynne V., Chavez, Dean, Davis, Clay, Lee, Sandra L., Patel, Bella Mayurkumar, Pu, Ling-Ling, Bell, Stephanie N., Johnson, Angela Jolivet, Vattathil, Selina, Williams, Rex L., Jr., Shigenobu, Shuji, Dang, Phat M., Morioka, Mizue, Fukatsu, Takema, Kudo, Toshiaki, Miyagishima, Shin-ya, Jiang, Huaiyang, Worley, Kim C., Legeai, Fabrice, Gauthier, Jean-Pierre, Collin, Olivier, Zhang, Lan, Chen, Hsiu-Chuan, Ermolaeva, Olga, Hlavina, Wratko, Kapustin, Yuri, Kiryutin, Boris, Kitts, Paul, Maglott, Donna, Murphy, Terence, Pruitt, Kim, Sapojnikov, Victor, Souvorov, Alexandre, Thibaud-Nissen, Francoise, Camara, Francisco, Guigo, Roderic, Stanke, Mario, Solovyev, Victor, Kosarev, Peter, Gilbert, Don, Gabaldon, Toni, Huerta-Cepas, Jaime, Marcet-Houben, Marina, Pignatelli, Miguel, Moya, Andres, Rispe, Claude, Ollivier, Morgane, Quesneville, Hadi, Permal, Emmanuelle, Llorens, Carlos, Futami, Ricardo, Hedges, Dale, Robertson, Hugh M., Alioto, Tyler, Mariotti, Marco, Nikoh, Naruo, McCutcheon, John P., Burke, Gaelen, Kamins, Alexandra, Latorre, Amparo, Moran, Nancy A., Ashton, Peter, Calevro, Federica, Charles, Hubert, Colella, Stefano, Douglas, Angela, Jander, Georg, Jones, Derek H., Febvay, Gerard, Kamphuis, Lars G., Kushlan, Philip F., Macdonald, Sandy, Ramsey, John, Schwartz, Julia, Seah, Stuart, Thomas, Gavin, Vellozo, Augusto, Cass, Bodil, Degnan, Patrick, Hurwitz, Bonnie, Leonardo, Teresa, Koga, Ryuichi, Altincicek, Boran, Anselme, Caroline, Atamian, Hagop, Barribeau, Seth M., de Vos, Martin, Duncan, Elizabeth J., Evans, Jay, Ghanim, Murad, Heddi, Abdelaziz, Kaloshian, Isgouhi, Vincent-Monegat, Carole, Parker, Ben J., Perez-Brocal, Vicente, Rahbe, Yvan, Spragg, Chelsea J., Tamames, Javier, Tamarit, Daniel, Tamborindeguy, Cecilia, Vilcinskas, Andreas, Bickel, Ryan D., Brisson, Jennifer A., Butts, Thomas, Chang, Chun-che, Christiaens, Olivier, Davis, Gregory K., Duncan, Elizabeth, Ferrier, David, Iga, Masatoshi, Janssen, Ralf, Lu, Hsiao-Ling, McGregor, Alistair, Miura, Toru, Smagghe, Guy, Smith, James, van der Zee, Maurijn, Velarde, Rodrigo, Wilson, Megan, Dearden, Peter, Edwards, Owain R., Gordon, Karl, Hilgarth, Roland S., Rider, Stanley Dean, Jr., Srinivasan, Dayalan, Walsh, Thomas K., Ishikawa, Asano, Jaubert-Possamai, Stephanie, Fenton, Brian, Huang, Wenting, Rizk, Guillaume, Lavenier, Dominique, Nicolas, Jacques, Smadja, Carole, Zhou, Jing-Jiang, Vieira, Filipe G., He, Xiao-Li, Liu, Renhu, Rozas, Julio, Field, Linda M., Ashton, Peter D., Campbell, Peter, Carolan, James C., Douglas, Angela E., Fitzroy, Carol I. J., Reardon, Karen T., Reeck, Gerald R., Singh, Karam, Wilkinson, Thomas L., Huybrechts, Jurgen, Abdel-latief, Mohatmed, Robichon, Alain, Veenstra, Jan A., Hauser, Frank, Cazzamali, Giuseppe, Schneider, Martina, Williamson, Michael, Stafflinger, Elisabeth, Hansen, Karina K., Grimmelikhuijzen, Cornelis J. P., Price, Daniel R. G., Caillaud, Marina, van Fleet, Eric, Ren, Qinghu, Gatehouse, John A., Brault, Veronique, Monsion, Baptiste, Diaz, Jason, Hunnicutt, Laura, Ju, Ho-Jong, Pechuan, Ximo, Aguilar, Jose, Cortes, Teresa, Ortiz-Rivas, Benjamin, Martinez-Torres, David, Dombrovsky, Aviv, Dale, Richard P., Davies, T. G. Emyr, Williamson, Martin S., Jones, Andrew, Sattelle, David, Williamson, Sally, Wolstenholme, Adrian, Cottret, Ludovic, Sagot, Marie France, Heckel, David G., and Hunter, Wayne

Abstract

Aphids are important agricultural pests and also biological models for studies of insect-plant interactions, symbiosis, virus vectoring, and the developmental causes of extreme phenotypic plasticity. Here we present the 464 Mb draft genome assembly of the pea aphid Acyrthosiphon pisum. This first published whole genome sequence of a basal hemimetabolous insect provides an outgroup to the multiple published genomes of holometabolous insects. Pea aphids are host-plant specialists, they can reproduce both sexually and asexually, and they have coevolved with an obligate bacterial symbiont. Here we highlight findings from whole genome analysis that may be related to these unusual biological features. These findings include discovery of extensive gene duplication in more than 2000 gene families as well as loss of evolutionarily conserved genes. Gene family expansions relative to other published genomes include genes involved in chromatin modification, miRNA synthesis, and sugar transport. Gene losses include genes central to the IMD immune pathway, selenoprotein utilization, purine salvage, and the entire urea cycle. The pea aphid genome reveals that only a limited number of genes have been acquired from bacteria; thus the reduced gene count of Buchnera does not reflect gene transfer to the host genome. The inventory of metabolic genes in the pea aphid genome suggests that there is extensive metabolite exchange between the aphid and Buchnera, including sharing of amino acid biosynthesis between the aphid and Buchnera. The pea aphid genome provides a foundation for post-genomic studies of fundamental biological questions and applied agricultural problems.

Published
2010
Full Text
View/download PDF

28. RNA interference in Lepidoptera: An overview of successful and unsuccessful studies and implications for experimental design

Author

Terenius, Olle, primary, Papanicolaou, Alexie, additional, Garbutt, Jennie S., additional, Eleftherianos, Ioannis, additional, Huvenne, Hanneke, additional, Kanginakudru, Sriramana, additional, Albrechtsen, Merete, additional, An, Chunju, additional, Aymeric, Jean-Luc, additional, Barthel, Andrea, additional, Bebas, Piotr, additional, Bitra, Kavita, additional, Bravo, Alejandra, additional, Chevalier, François, additional, Collinge, Derek P., additional, Crava, Cristina M., additional, de Maagd, Ruud A., additional, Duvic, Bernard, additional, Erlandson, Martin, additional, Faye, Ingrid, additional, Felföldi, Gabriella, additional, Fujiwara, Haruhiko, additional, Futahashi, Ryo, additional, Gandhe, Archana S., additional, Gatehouse, Heather S., additional, Gatehouse, Laurence N., additional, Giebultowicz, Jadwiga M., additional, Gómez, Isabel, additional, Grimmelikhuijzen, Cornelis J.P., additional, Groot, Astrid T., additional, Hauser, Frank, additional, Heckel, David G., additional, Hegedus, Dwayne D., additional, Hrycaj, Steven, additional, Huang, Lihua, additional, Hull, J. Joe, additional, Iatrou, Kostas, additional, Iga, Masatoshi, additional, Kanost, Michael R., additional, Kotwica, Joanna, additional, Li, Changyou, additional, Li, Jianghong, additional, Liu, Jisheng, additional, Lundmark, Magnus, additional, Matsumoto, Shogo, additional, Meyering-Vos, Martina, additional, Millichap, Peter J., additional, Monteiro, Antónia, additional, Mrinal, Nirotpal, additional, Niimi, Teruyuki, additional, Nowara, Daniela, additional, Ohnishi, Atsushi, additional, Oostra, Vicencio, additional, Ozaki, Katsuhisa, additional, Papakonstantinou, Maria, additional, Popadic, Aleksandar, additional, Rajam, Manchikatla V., additional, Saenko, Suzanne, additional, Simpson, Robert M., additional, Soberón, Mario, additional, Strand, Michael R., additional, Tomita, Shuichiro, additional, Toprak, Umut, additional, Wang, Ping, additional, Wee, Choon Wei, additional, Whyard, Steven, additional, Zhang, Wenqing, additional, Nagaraju, Javaregowda, additional, ffrench-Constant, Richard H., additional, Herrero, Salvador, additional, Gordon, Karl, additional, Swevers, Luc, additional, and Smagghe, Guy, additional

Published
2011
Full Text
View/download PDF

32. Assessment of species specificity of moulting accelerating compounds in Lepidoptera: comparison of activity between Bombyx mori and Spodoptera littoralis by in vitro reporter and in vivo toxicity assays

Author

Soin, Thomas, primary, De Geyter, Ellen, additional, Mosallanejad, Hadi, additional, Iga, Masatoshi, additional, Martín, David, additional, Ozaki, Shunsuke, additional, Kitsuda, Shigeki, additional, Harada, Toshiyuki, additional, Miyagawa, Hisashi, additional, Stefanou, Dimitra, additional, Kotzia, Georgia, additional, Efrose, Rodica, additional, Labropoulou, Vassiliki, additional, Geelen, Danny, additional, Iatrou, Kostas, additional, Nakagawa, Yoshiaki, additional, Janssen, Colin R, additional, Smagghe, Guy, additional, and Swevers, Luc, additional

Published
2010
Full Text
View/download PDF

37. Impact of punctual mutations in the cap gene of Junonia coenia densovirus (JcDNV) on virus assembly and infectivity to Ld 652 cells and Spodoptera littoralis larvae

Author

Iatrou, Kostas, Couble, Pierre, Abd-Alla, A., Jousset, F-X., Cousserans, F., Bergoin, M., Abe, H., Fujii, T., Mita, K., Ajimura, M., Shimada, T., Sahara, K., Tamura, T., Altstein, M., Hariton, A., Davidovitch, M., Ben-Aziz, O., Barat-Houari, M., Hilliou, F., Jousset, F.-X., Sofer, L., Deleury, E., Rocher, J., Ravallec, M., Galibert, L., Feyereisen, R., Fournier, P., Volkoff, A-N., Baxter, Simon W., Chamberlain, Nicola, Papa, Riccardo, Humphray, Sean J., ffrench-Constant, Richard H., McMillan, W. Owen, Jiggins, Chris D., Behere, G.T., Russell, D., Batterham, P., Tay, W. T., Beldade, P., Rudd, S., Gruber, J.D., Long, A.D., Breugelmans, B., Simonet, G., de Velde, S. Van, Soest, S. Van, Smagghe, G., Broeck, J. Vanden, Clark, R., Brown, S., Heckel, D., Jiggins, C. D., Collins, S., Vogler, A. P, Chamberlain, N., Baxter, S., Jiggins, C., ffrench-Constant, R.H., Chortyk, O., Friz, J., Thompson, C., Kumar, P., Tice, C., Vertin, B., Palli, R., Kumar, M., Meyer, A., Meteyer, T., Smith, H., Cress, D., Li, B., Hormann, R., Collinge, Derek, Gordon, Karl, Behm, Carolyn, Whyard, Steve, Alençon, d', Audant, E., Bernard-Samain, P., Bidegainberry, S., Brehélin, V., Brun-Barale, M., Cousserans, A., Duvic, C., Escoubas, B., Feyereisen, J-M., Fournier, R., Gagneur, Ph., Gordon, C., Gimenez, K., Heckel, S., Hotelier, D., Hilliou, Th., Mita, F., Negre, K., Sabourault, V., Suraporn, C., Volkoff, S., Weissenbach, N., Maria, De Simone Anna, Angela, Sorrentino, Francesca, Di Cara, Polito, Lino, Anna, Digilio F., Drezen, J-M, Bezier, A., Lesobre, J., Huguet, E., Dupuy, C., Eleftherianos, I., Millichap, P. J., Felföldi, G., Gökcen, F., Waterfield, N., Clarke, D. J., ffrench-Constant, R. H., Reynolds, S. E., Elias, M., Joron, M., Willmott, K., Kaiser, V., Silva-Brandão, K. L., Freitas, A.V.L., Arias Mejía, C., Gomez Pineres, L.M., Brower, A.V.Z., Escoubas, J.-M., Girard, P.-A., Volkoff, N., Boublik, Y., D'Alençon, E., Taillez, P., Brehélin, M., Venekei, I., Fischer, H. M., Wheat, C. W., Wittstock, U., Heckel, D. G., Vogel, H., Freitak, D., Katsuma, S., Futahashi, R., Fujiwara, H., Garel, Annie, Briolay, Jérôme, Brouilly, Patrick, Royer, Corinne, Sasanuma, Shun-ichi, Sasanuma, Motoe, Keime, Céline, Gandrillon, Olivier, Chavancy, Gérard, Mita, Kasuei, Geber, M., Faye, I., Terenius, O., Goldsmith, M., Proestou, D., Carter, D., Nicholson, E., Wu, C., Zhang, H., Gopinathan, K. P., Parthasarathy, R., Dhawan, S., Gordon, K., Colebatch, G., Campbell, P.M., Horne, I., East, P.D., Hughes, T.M., Marcus, J.M., Serbielle, C., Douris, V., Lalmanach, G., Iatrou, K., Iga, Masatoshi, Sekimoto, Takayuki, Elmogy, Mohamed, Iwami, Masafumi, Sakurai, Sho, Jacquin-Joly, E., Merlin, C., Malpel, S., Pelletier, J., Brigaud, I., François, M-C., Maïbèche, M., Jarvis, D.L., Aumiller, J.J., Geisler, C., Hensley, J., Hollister, J.R., Shi, X., Jiggins, Chris D, Joron, Mathieu, Mallet, James, Jostova, P., Svatos, A., Pichova, Iva, Kadono-Okuda, K., Ito, K., Nohata, J., Yamamoto, K., Sasanuma, M., Sasanuma, S., Eguchi, R., Hara, W., Kiyokawa, I., Kobayashi, I., Uchino, K., Sezutsu, H., Kanda, T., Miura, T., Ohashi, T., Katayama, K., Kourti, A., Gkouvitsas, T., Kusakabe, T., Mon, H., Takahashi, M., Lee, J.M., Kawaguchi, Y., Labropoulou, V., Stefanou, D., Magkrioti, C., Andronopoulou, E., Swevers, L., Lapointe, R., Tanaka, K., Barney, W., Whitfield, J., Banks, J., Béliveau, C., Stoltz, D., Webb, B.A., Cusson, M., Lee, Siu Fai, Heckel, David G., Li, Yi, Guarino, Linda A., Li, Muwang, Li, Minhui, Guo, Qiuhong, Miao, Xuexia, Hou, Chengxiang, Lin, Hongxuan, Huang, Yongping, Li, Lan, Zheng, Sichun, Ladd, Tim, Zhang, Dayu, Buhlers, Deborah, Krell, Peter J., Arif, Basil M., Retnakaran, Arthur, Feng, Qili, Doucet, Daniel, Machado, Ednildo, Swevers, Luc, Makhijani, Kalpana, Bharathi, V, Kannan, Ramakrishnan, Shashidhara, L S, Mauchamp, Bernard, Jalabert, Audrey, Rocha, Martine Da, Grenier, Anne-Marie, Labas, Valérie, Vinh, Joëlle, Mita, Kazuei, Kadono-Okuda, Keiko, Miao, Yungen, Yue, Wanfu, Li, Xinghua, Wu, Xiaofeng, Miller, T.A., Park, Y., Ren, X., Kasahara, M., Sasaki, S., Nagayasu, Y., Yamada, T., Kanamori, H., Namiki, N., Kitagawa, M., Yamashita, H., Yasukochi, Y., Rvikumar, G., Shimomura, M., Nagamura, Y., Shin-I, T., Morishita, S., Sasaki, T., Sugahara, R., Monteiro, Antónia, Chen, Bin, Ramos, Diane, Kamal, Firdous, Glaser, Gary, Stockslager, Steven, Nieberding, C., Schneider, V., Vos, H. De, Lassance, J.M., Lofstedt, C., Brakefield, P.M., Nighorn, A., Papanicolaou, A., Blaxter, M.L., Jiggins, C.D., Papantonis, A., Sourmeli, S., Lecanidou, R., Rocha, M. Da, Royer, C., Pennacchio, F., Falabella, P., Varricchio, P., Malva, C., Pohl, Nelida, Sison-Mangus, Marilou, Briscoe, Adriana D., Saenko, S.V., Satish, V., Shukla, J.N., Nagaraju, J., Frank, Scholz, Tine, Lesch, Susann, Beez, Traute, Holthusen, Ines, Anderl, Geuenich, Silvia, Tina, Trenczek, Kojima, K., Niimi, T., Hatakeyama, M., Shiotsuki, Takahiro, Tan, An-Jiang, Tamura, Toshiki, Simpson, Robert, Newcomb, Richard, Beuning, Lesley, Yauk, Yah-Khing, Crowhurst, Ross, Gatehouse, Heather, Gatehouse, Laurence, Markwick, Ngaire, Chagne, Dave, Gleave, Andrew, Christeller, John, Strand, M. R., Soin, T., Loocke, K. Van, Wheelock, C., Harada, T., Akamatsu, M., Nakagawa, Y., Truman, JW, Hiruma, K, Allee, JP, MacWhinnie, SGB, Champlin, D, Riddiford, LM, Turnbull, M.W., Vitkova, M., Kubickova, S., Marec, F., Kroymann, J., Mithöfer, A., Boland, W., Vogt, R.G., Franco, M-d., Bohbot, J, Fernandez, K., Kobres, P., Hanna, J., Poppy, J., Webb, Bruce A., Gill, Torrence A., Fath-Goodin, Angelika, Kroemer, Jeremy, Wedde, M., Altincicek, B., Vilcinskas, A., Wee, Choon Wei, Robin, Charles, Heckel, David G, Wheat, Christopher W., Labandeira, Conrad, Andolfatto, P., Feng, Q., Simpson, R., Vogel, Heiko, Williams, A. K., Xia, Qingyou, Zhou, Zeyang, Lu, Cheng, Xiang, Zhonghuai, Zhang, Liang, Yamamoto, Kimiko, Narukawa, Junko, Nohata, Junko, Suetsugu, Yoshitaka, Minami, Hiroshi, Shimomura, Michihiko, Yukuhiro, K., Itoh, M., Banno, Y., Kômoto, N., Kosegawa, E., Hirokawa, M., Tatematsu, K., Nishimura, M., Maekawa, H., Kawanishi, Y., Nakajima, Y., and Krell, Peter J

Subjects
Article
Published
2007

38. Pigment Dispersing Factor Regulates Ecdysone Biosynthesis via Bombyx Neuropeptide G Protein Coupled Receptor-B2 in the Prothoracic Glands of Bombyx mori.

Author

Iga, Masatoshi, Nakaoka, Takayoshi, Suzuki, Yutaka, and Kataoka, Hiroshi

Subjects
*G protein coupled receptors, *PIGMENTS, *ECDYSONE, *BIOSYNTHESIS, *NEUROPEPTIDES, *SILKWORMS, *INSECT growth, *HORMONE regulation
Abstract

Ecdysone is the key hormone regulating insect growth and development. Ecdysone synthesis occurs in the prothoracic glands (PGs) and is regulated by several neuropeptides. Four prothoracicotropic and three prothoracicostatic factors have been identified to date, suggesting that ecdysone biosynthesis is intricately regulated. Here, we demonstrate that the neuropeptide pigment dispersing factor (PDF) stimulates ecdysone biosynthesis and that this novel signaling pathway partially overlaps with the prothoracicotropic hormone (PTTH) signaling pathway. We performed transcriptome analysis and focused on receptors predominantly expressed in the PGs. From this screen, we identified a candidate orphan G protein coupled receptor (GPCR), Bombyx neuropeptide GPCR-B2 (BNGR-B2). BNGR-B2 was predominantly expressed in ecdysteroidogenic tissues, and the expression pattern in the PGs corresponded to the ecdysteroid titer in the hemolymph. Furthermore, we identified PDF as a ligand for BNGR-B2. PDF stimulated ecdysone biosynthesis in the PGs, but the stimulation was only observed in the PGs during a specific larval stage. PDF did not affect the transcript level of known ecdysone biosynthetic enzymes, and inhibiting transcription did not suppress ecdysone biosynthesis, suggesting that the effects of PDF might be mediated by translational regulation and/or post-translational modification. In addition, the participation of protein kinase A (PKA), phosphatidylinositol 3-kinase (PI3K), target of rapamycin (TOR) and eukaryotic translation initiation factor 4E (eIF4E)-binding protein (4E-BP) in the PDF signaling pathway was discovered. [ABSTRACT FROM AUTHOR]

Published
2014
Full Text
View/download PDF

39. Pigment Dispersing Factor Regulates Ecdysone Biosynthesis via Bombyx Neuropeptide G Protein Coupled Receptor-B2 in the Prothoracic Glands of Bombyx mori.

Author

Iga, Masatoshi, Nakaoka, Takayoshi, Suzuki, Yutaka, and Kataoka, Hiroshi

Subjects
G protein coupled receptors, PIGMENTS, ECDYSONE, BIOSYNTHESIS, NEUROPEPTIDES, SILKWORMS, INSECT growth, HORMONE regulation
Abstract

Ecdysone is the key hormone regulating insect growth and development. Ecdysone synthesis occurs in the prothoracic glands (PGs) and is regulated by several neuropeptides. Four prothoracicotropic and three prothoracicostatic factors have been identified to date, suggesting that ecdysone biosynthesis is intricately regulated. Here, we demonstrate that the neuropeptide pigment dispersing factor (PDF) stimulates ecdysone biosynthesis and that this novel signaling pathway partially overlaps with the prothoracicotropic hormone (PTTH) signaling pathway. We performed transcriptome analysis and focused on receptors predominantly expressed in the PGs. From this screen, we identified a candidate orphan G protein coupled receptor (GPCR), Bombyx neuropeptide GPCR-B2 (BNGR-B2). BNGR-B2 was predominantly expressed in ecdysteroidogenic tissues, and the expression pattern in the PGs corresponded to the ecdysteroid titer in the hemolymph. Furthermore, we identified PDF as a ligand for BNGR-B2. PDF stimulated ecdysone biosynthesis in the PGs, but the stimulation was only observed in the PGs during a specific larval stage. PDF did not affect the transcript level of known ecdysone biosynthetic enzymes, and inhibiting transcription did not suppress ecdysone biosynthesis, suggesting that the effects of PDF might be mediated by translational regulation and/or post-translational modification. In addition, the participation of protein kinase A (PKA), phosphatidylinositol 3-kinase (PI3K), target of rapamycin (TOR) and eukaryotic translation initiation factor 4E (eIF4E)-binding protein (4E-BP) in the PDF signaling pathway was discovered. [ABSTRACT FROM AUTHOR]

Published
2014
Full Text
View/download PDF

41. Ca2+-PKC-caspase 3-like protease pathway mediates DNA and nuclear fragmentation in ecdysteroid-induced programmed cell death

Author

Iga, Masatoshi, Manaboon, Manaporn, Matsui, Hiroto, and Sakurai, Sho

Subjects
*PROTEIN kinase C, *DNA, *NUCLEAR fragmentation, *ECDYSTEROIDS, *CELL death, *CALMODULIN, *IONOPHORES, *CELLULAR signal transduction
Abstract

Abstract: 20-Hydroxyecdysone (20E) induces programmed cell death in the anterior silk gland of the silkworm. Here, we report the direct interaction between Ca2+ and protein kinase C (PKC)-caspase 3-like protease pathway in the 20E-induced cell death. The calcium ionophore can mimic 20E effects in inducing DNA and nuclear fragmentation, but such mimicry is only possible in the glands precultured for 18h with 20E. The simultaneous presence of translation inhibitor with 20E in the preculture showed that de novo protein synthesis was needed to mimic 20E effects by the calcium ionophore. Both a PKC inhibitor and a caspase 3 inhibitor inhibited the mimicking effects. After substitution of the calcium ionophore for 20E, caspase 3-like protease was fully activated 12h later, and DNA and nuclear fragmentation occurred faster than continuous 20E stimuli. The results show the presence of a Ca2+-PKC-caspase 3-like protease pathway in 20E signaling, and possible involvement of the pathway up to the mobilization of Ca2+ in regulating the timing of cell death in vivo. [Copyright &y& Elsevier]

Published
2010
Full Text
View/download PDF

42. Intracellular mobilization of Ca2+ by the insect steroid hormone 20-hydroxyecdysone during programmed cell death in silkworm anterior silk glands

Author

Manaboon, Manaporn, Iga, Masatoshi, Iwami, Masafumi, and Sakurai, Sho

Subjects
*CALCIUM ions, *INSECT hormones, *STEROID hormones, *ECDYSONE, *CELL death, *SILKWORMS, *CELLULAR signal transduction, *PHYSIOLOGY
Abstract

Abstract: 20-Hydroxyecdysone (20E) triggers programmed cell death (PCD) and regulates de novo gene expression in the anterior silk glands (ASGs) of the silkworm Bombyx mori. PCD is mediated via a nongenomic pathway that includes Ca2+ as a second messenger and the activation of protein kinase C/caspase-3-like protease; however, the steps leading to a concomitant buildup of intracellular Ca2+ are unknown. We employed pharmacological tools to identify the components of this pathway. ASGs were cultured in the presence of 1μM 20E and one of the following inhibitors: a G-protein-coupled receptor (GPCR) inhibitor, a phospholipase C (PLC) inhibitor, an inositol 1,4,5-trisphosphate receptor (IP3R) antagonist, and an L- or T-type Ca2+ channel blocker. The T-type Ca2+ channel blocker inhibited 20E-induced nuclear and DNA fragmentation; in contrast, PCD was induced by 20E in Ca2+-free medium, indicating that the source of Ca2+ is an intracellular reservoir. The IP3R antagonist inhibited nuclear and DNA fragmentation, suggesting that the endoplasmic reticulum may be the Ca2+ source. Finally, the GPCR and PLC inhibitors effectively blocked nuclear and DNA fragmentation. Our results indicate that 20E increases the intracellular level of Ca2+ by activating IP3R, and that this effect may be brought about by the serial activation of GPCR, PLC, and IP3. [Copyright &y& Elsevier]

Published
2009
Full Text
View/download PDF

43. Identification and characterization of the diuretic hormone 31 receptor in the silkworm Bombyx mori

Author

Iga, Masatoshi and Kataoka, Hiroshi

Abstract

The receptor for diuretic hormone 31 (DH31R) was identified in the silkworm Bombyx mori. A heterologous expression system revealed that an orphan G-protein coupled receptor, BNGR-B1, responded to DH31 and upregulated the intracellular cAMP level. DH31R(BNGR-B1) was predominantly expressed in the anterior silk gland, midgut, and ovary, whereas DH31was predominantly expressed in the central nervous system and midgut.

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results