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Limitations inherent to existing statistical distributions in capturing the complexities of real-world data often necessitate the development of novel models. This paper introduces the new exponential generalized inverse generalized Weibull (NEGIGW) distribution. The NEGIGW distribution boasts significant flexibility with symmetrical and asymmetrical shapes, allowing its hazard rate function to be adapted to many failure patterns observed in various fields such as medicine, biology, and engineering. Some statistical properties of the NEGIGW distribution, such as moments, quantile function, and Renyi entropy, are studied. Three methods are used for parameter estimation, including maximum likelihood, maximum product of spacing, and percentile methods. The performance of the estimation methods is evaluated via Monte Carlo simulations. The NEGIGW distribution excels in its ability to fit real-world data accurately. Five medical and engineering datasets are applied to demonstrate the superior fit of NEGIGW distribution compared to competing models. This compelling evidence suggests that the NEGIGW distribution is promising for lifetime data analysis and reliability assessments across different disciplines.