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Your search keyword '"Iborra, J.L."' showing total 119 results
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119 results on '"Iborra, J.L."'

23. Toward green processes for fine chemicals synthesis : biocatalysis in ionic liquid supercritical carbon dioxide biphasic systems

Author

Lozano, P., De Diego, T., Gmouh, S., Vaultier, M., Iborra, J.L., Chimie et Photonique Moléculaires (CPM), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS), Barbedor, Catherine, and Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS)

Subjects
ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2007

24. Research Letter: is neuroticism a risk factor for postpartum depression?

Author

Universitat Politècnica de Catalunya. Departament d'Estadística i Investigació Operativa, Universitat Politècnica de Catalunya. GREMA - Grup de Recerca en Estadística Matemàtica i les seves Aplicacions, Mayoral, F, Martín-Santos, Rocío, Gelabert, Estel, Subirà, S., Gutierrez-Zotes, A, Langohr, Klaus, Jover, M., Torrens, Marta, Guillamat, R, Vilella, E., de Frutos, R., Roca, M., Guitart, M., Navinés, Ricard, Gornemann, I., Costas, J., Gratacos, Mònica, Iborra, J.L., Canellas, F, Valdés, M., García Esteve, L., Sanjuan, S., Universitat Politècnica de Catalunya. Departament d'Estadística i Investigació Operativa, Universitat Politècnica de Catalunya. GREMA - Grup de Recerca en Estadística Matemàtica i les seves Aplicacions, Mayoral, F, Martín-Santos, Rocío, Gelabert, Estel, Subirà, S., Gutierrez-Zotes, A, Langohr, Klaus, Jover, M., Torrens, Marta, Guillamat, R, Vilella, E., de Frutos, R., Roca, M., Guitart, M., Navinés, Ricard, Gornemann, I., Costas, J., Gratacos, Mònica, Iborra, J.L., Canellas, F, Valdés, M., García Esteve, L., and Sanjuan, S.

Abstract

Although the relationship between personality and depressive illness is complex (Shea, 2005), there is empirical evidence that some personality features such as neuroticism, harm avoidance, introversion, dependency, self-criticism or perfectionism are related to depressive illness risk (Gunderson et al. 1999). Moreover, personality traits, especially neuroticism, may explain the increased prevalence of depression among females (Goodwin & Gotlib, 2004). Few studies have explored neuroticism, extraversion and psychoticism as risk factors for depression after an event as stressful as childbirth. Pitt (1968) was the first author to report high scores on neuroticism and low scores on extraversion among postpartum depressed women. Similar results were found in a comparison of mothers with and without postpartum depressive symptoms (Dudley et al. 2001; Podolska et al. 2010). A case-control study comparing women with recurrent major depression with and without a history of postpartum depression found no personality trait differences between them; however, those with a history of postpartum depression showed higher neuroticism and psychoticism and lower extraversion than controls. These results suggested that these traits did not confer a specific risk for the postnatal onset episodes (Jones et al. 2010). Prospective studies have also studied the link between personality and postpartum depression; however, these data are not conclusive due to methodological limitations, such as sample size (Kumar & Robson, 1984; Watson et al. 1984; Areias et al. 1991; Boyce et al. 1991; Matthey et al. 2000), selection bias (Kumar & Robson, 1984; Areias et al. 1991; Boyce et al. 1991; Matthey et al. 2000), or depression assessment (self-report measures versus clinical diagnosis: Boyce et al. 1991; Matthey et al. 2000; Dudley et al. 2001; Saisto et al. 2001; Van Bussel et al. 2009) or because the authors did not take into account confounding factors such as stressful life events or social supp, Peer Reviewed, Postprint (published version)

Published
2012

44. Whole cell biocatalysts stabilization for l-carnitine production.

Author

Cánovas, M. and Iborra, J.L.

Subjects
*ENZYMES, *CELLS, *CARNITINE, *BIOTRANSFORMATION (Metabolism), *ESCHERICHIA coli
Abstract

We present how whole cells can be used in different ways to stabilize enzyme catalysts in the cell environment to perform biotransformations. Some of the factors which affect their use in biotransformations, such as the nature of the substrate/product, the reusability of cells, the extension of cell viability by cell activation periods or the addition of energetic substrates and the stabilization in solids supports, are considered. The use of sufficiently active enzymes in the cell environment to perform biotransformations within growing, resting, permeabilized, dried, osmotically stressed, freely suspended and immobilized cells, is discussed in the text. The different cell states of enterobacteria, such as Escherichia coli and Proteus sp., can be used to produce l-carnitine from crotonobetaine or d-carnitine substrate, are analyzed. [ABSTRACT FROM AUTHOR]

Published
2005
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46. Integrating the Microkinetics of the L-Carnitine and Central Metabolism in Escherichia coliwith the Macrokinetics of a High-Cell Density Reactor

Author

Cánovas, M., Sevilla, A., Bernal, V., Iborra, J.L., and Torres, N.V.

Abstract

A combined E. colicell metabolism-bioreactor system is described using an S-system model developed within the Biochemical System Theory framework. Such a model is able to represent the activities of the enzymes involved in the biotransformation process, the biotransformation compound concentrations and their transporter. In addition, the transporter is described as an ATP-dependent antiport of betaines and by considering the difference between the concentration of substrate (crotronobetaine) and product (L-carnitine) inside/outside (reactor bulk) the cell. The central metabolism, including glycerol assimilation through the glycolytic and the tricarboxylic acid pathway (TCA) and the synthesis of lactate, formate and acetate has also been modelled. Simulation results matched experiments run with the high-cell density reactor system.

Published
2004
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