1. Community-acquired Haemophilus influenzae pneumonia--New insights from the CAPNETZ study
- Author
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Christina Forstner, Gernot Rohde, Jan Rupp, Hartwig Schuette, Sebastian R. Ott, Stefan Hagel, Nicole Harrison, Florian Thalhammer, Heike von Baum, Norbert Suttorp, Tobias Welte, Mathias W. Pletz, S. Krüger, D. Frechen, W. Knüppel, I. Armari, D. Stolz, N. Suttorp, H. Schütte, P. Creutz, T. Bauer, J. Hecht, W. Pankow, A. Lies, D. Thiemig, B. Hauptmeier, D. Wehde, M. Suermann, S. Ewig, M. Prediger, G. Zernia, T. Welte, J. Rademacher, G. Barten, M. Abrahamczik, J. Naim, W. Kröner, T. Illig, N. Klopp, C. Kroegel, M. Pletz, R. Bals, K. Dalhoff, S. Schütz, R. Hörster, G. Rohde, W. Petermann, H. Buschmann, R. Kröning, Y. Aydin, T. Schaberg, I. Hering, R. Marre, C. Schumann, H. von Baum, T. Illmann, M. Wallner, O. Burghuber, G. Rainer, Pulmonologie, RS: NUTRIM - R3 - Chronic inflammatory disease and wasting, and MUMC+: MA Med Staf Spec Longziekten (9)
- Subjects
0301 basic medicine ,Microbiology (medical) ,Adult ,Male ,medicine.medical_specialty ,Haemophilus Infections ,Respiratory tract infection ,Adolescent ,medicine.drug_class ,030106 microbiology ,Antibiotics ,Chronic liver disease ,medicine.disease_cause ,Haemophilus influenzae ,03 medical and health sciences ,Young Adult ,Internal medicine ,Germany ,Severity of illness ,CURB-65 score ,Pneumonia, Bacterial ,Medicine ,Humans ,Beta-lactams ,Prospective Studies ,Young adult ,Prospective cohort study ,Intensive care medicine ,610 Medicine & health ,Pathogen ,Aged ,Aged, 80 and over ,business.industry ,Middle Aged ,medicine.disease ,Anti-Bacterial Agents ,Community-Acquired Infections ,Pneumonia ,Infectious Diseases ,Treatment Outcome ,Female ,Macrolides ,business ,Fluoroquinolones - Abstract
Objectives: We aimed to identify clinical characteristics and to assess effectiveness of different initial antibiotic regimens in adult patients with community-acquired pneumonia (CAP) caused by Haemophilus influenzae. Methods: Characteristics were compared between patients with H. influenzae monoinfection versus CAP of other and unknown aetiology enrolled by the German prospective cohort study CAPNETZ. Impact of initial antibiotic treatment on "early clinical response" according to FDA criteria and overall clinical cure were analysed. Results: H. influenzae was found in 176 out of 2790 patients with pathogen detection (6.3%). Characteristics significantly associated with a H. influenzae CAP (p
- Published
- 2015