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1. Common Food Sources for Macrobenthic Communities in Different Bottom Covers: Submerged Macrophytes and Benthic Cyanobacteria in a Japanese Temperate Lake

Author: Kenzi Takamura, Natsuko I. Kondo, and Nobuyoshi Nakajima
Subjects: benthic crustacean, Chironomid, Microseira wollei, stable‐isotope analysis, submerged macrophyte, Ecology, QH540-549.5
Abstract: ABSTRACT Macrobenthic communities in a lake are affected by the type of bottom cover such as macrophytes or algae. In the southern basin of Lake Biwa, mats of the benthic cyanobacteria (BC) Microseira wollei widely cover the lake bottom and are interspersed with submerged macrophytes (SMs). Because different macrobenthos species appear to occur at those bottoms, we investigated the composition of the communities. Furthermore, as M. wollei is supposed to be inedible to consumer organisms owing to its hard sheath and toxins, the food possibility of the cyanobacteria and macrophytes for macrobenthos was analyzed. In this study, macrobenthos were collected, identified molecularly, counted in the BC and SM zones, and analyzed for carbon and nitrogen stable‐isotopic compositions. In the BC zone, asellids and amphipods dominated the macrobenthic community, while chironomids dominated the SM zone. The stable‐isotope analysis revealed that M. wollei was a minor food source for macrobenthos and other higher‐level consumers, with some macrophytes, particulate organic matter and bottom sediment potentially being a major source. The dominance of crustacean macrobenthos in M. wollei mats suggested that they provided a refuge from predation for crustaceans, whereas SMs were not sufficiently abundant to achieve this. Although different macrobenthic communities in the BC and SM zones were likely supported by common food sources, with the exeption of M. wollei, the present study was conducted over a short period and lacked advanced methods for gut content analysis. Therefore, further monitoring and food web analysis are required.
Published: 2024
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2. Phylogeography and genetic diversity of the Japanese mud shrimp Upogebia major (Crustacea, Decapoda, Upogebiidae): Natural or anthropogenic dispersal?

Author: Kyosuke Kitabatake, Kentaro Izumi, Natsuko I. Kondo, and Kenji Okoshi
Subjects: Zoology, QL1-991
Abstract: Upogebia major (De Haan, 1841) is known for forming huge burrows in sandy, intertidal areas that can extend to depths of over 2 m. Despite its widespread distribution in East Asia and Russia, the genetic relatedness of its regional populations remains uncertain, likely owing to difficulties in specimen collection. Therefore, to appraise the phylogeographic patterns, genetic diversity, and morphological variety of U. major, the mitochondrial DNA of specimens collected from Japan, Korea and China were subjected to molecular phylogenetic analyses of COI genes, alongside morphological assessment. As a result, we discovered four principal groups; of these, Group 1 consisted predominantly of Japanese specimens, while Groups 3 and 4 were interpreted as having originated from the continent. Group 2 exhibited genetic segregation from both continental and Japanese descent. Group 1 mostly comprising Japanese specimens implies that the planktonic larvae of U. major were disseminated north and south by ocean currents encompassing the Japanese archipelago. In contrast, individuals probably originating from the continent were discovered in Lake Notoro, Hokkaido and Matsukawa-ura, Fukushima in northeastern Japan, indicating possible introduction from the continent through ocean currents or unintentional introduction with other organisms imported. Additionally, one of the specimens collected from Matsukawa-ura exhibited significant genetic and morphological differences from other specimens, suggesting the possibility of being a subspecies. The outcomes of this study not only offer valuable insights into the origins of distribution of U. major but also introduce a novel challenge of assessing the coexistence of two routes: natural and anthropogenic dispersion.
Published: 2023
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3. Vertical eDNA distribution of cold‐water fishes in response to environmental variables in stratified lake

Author: Kayoko Fukumori, Natsuko I. Kondo, Ayato Kohzu, Kenji Tsuchiya, Hiroshi Ito, and Taku Kadoya
Subjects: eDNA, metabarcoding, salmon, species detection, stratification, Ecology, QH540-549.5
Abstract: Abstract In summer, the survival zones of cold‐water species are predicted to narrow by both increasing water temperatures from the surface and by expanding hypoxic zones from the lake bottom. To examine how the abundance of cold‐water fishes changes along environmental gradients, we assessed the vertical environmental DNA (eDNA) distributions of three salmonid species which may have different water temperature tolerances during both stratification and turnover periods using quantitative PCR (qPCR). In addition, we examined on the vertical distribution of diverse fish fauna using an eDNA metabarcoding assay. The results suggested that the kokanee salmon (Oncorhynchus nerka) eDNA were abundant in deep, cold waters. On the other hand, rainbow trout (O. mykiss) eDNA were distributed uniformly throughout the water column, suggesting that they may have high water‐temperature tolerance compared with kokanee salmon. The eDNA concentrations of masu salmon (O. masou) were below the detection limit (i.e.,
Published: 2024
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4. Use of legacy nitrogen as a resource: Unfertilized lotus fields contribute to water quality improvement and biodiversity conservation

Author: Shin-ichiro S. Matsuzaki, Ayato Kohzu, Mirai Watanabe, Natsuko I. Kondo, and Aiko Tatsuta
Subjects: Abandonment, Environmental DNA, Legacy, Sustainable farming, Watershed management, Environmental sciences, GE1-350
Abstract: Managing legacy nitrogen (N) that has accumulated over decades of intensive agriculture is necessary to balance agricultural production and environmental conservation. Using legacy N as a resource can reduce extant legacy N. The uplands of Japan's Lake Inba watershed are dominated by agroecosystems, and spring waters in the lowlands contain high NO3-N concentrations. We focused on an unfertilized, commercial lotus (Nelumbo nucifera) farm where paddy fields are irrigated with spring waters. We hypothesized that the lotus field could reduce the export of legacy N and provide habitat for fish (co-benefit). Dating of spring waters using sulfur hexafluoride revealed that the residence time of water at the study site was 12.5 years and suggested that the spring waters contained legacy N. We found large reductions of NO3-N and total nitrogen (TN) concentrations in water that passed through the lotus fields. A meta-analysis revealed that the reductions of NO3-N concentrations were highest in unfertilized lotus fields, and reductions of TN concentrations were higher in unfertilized paddy and lotus fields than in fertilized fields. The N removal by harvesting lotus roots 38.7 kg N/ha/year was smaller than the literature-based rate of N removal by denitrification. We used environmental DNA metabarcoding to identify the fish fauna in the lotus fields and an adjacent stream. The native fish richness was a little lower in the lotus fields than in the stream, but the presence of two endangered fish species in the lotus field suggested a moderate biodiversity conservation function. Our case study could be a good example of a nature-based solution to harness ecosystem functions to reduce legacy N.
Published: 2023
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5. A Wide Orbit Exoplanet OGLE-2012-BLG-0838Lb

Author: R., Poleski, D., Suzuki, A., Udalski, X., Xie, C., Yee J., N., Koshimoto, S., Gaudi B., A., Gould, J., Skowron, K., Szymanski M., I., Soszynski, P., Pietrukowicz, S., Kozlowski, L., Wyrzykowski, K., Ulaczyk, F., Abe, K., Barry R., P., Bennett D., A., Bhattacharya, A., Bond I., M., Donachie, H., Fujii, A., Fukui, Y., Itow, Y., Hirao, Y., Kamei, I., Kondo, A., Li M. C., Y., Matsubara, S., Miyazaki, Y., Muraki, M., Nagakane, C., Ranc, J., Rattenbury N., K., Satoh Y., H., Shoji, H., Suematsu, J., Sullivan D., T., Sumi, J., Tristram P., T., Yamakawa, T., Yamawaki, A., Yonehara, C., Han, S., Dong, M., Morzinski K., R., Males J., M., Close L., W., Pogge R., -P., Beaulieu J., and -B, Marquette J.
Subjects: Astrophysics - Earth and Planetary Astrophysics
Abstract: We present the discovery of a planet on a very wide orbit in the microlensing event OGLE-2012-BLG-0838. The signal of the planet is well separated from the main peak of the event and the planet-star projected separation is found to be twice larger than the Einstein ring radius, which roughly corresponds to a projected separation of ~4 AU. Similar planets around low-mass stars are very hard to find using any technique other than microlensing. We discuss microlensing model fitting in detail and discuss the prospects for measuring the mass and distance of lens system directly., Comment: 26 pages, 11 figures
Published: 2019
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6. Kepler K2Campaign 9 – II. First space-based discovery of an exoplanet using microlensing

Author: D Specht, R Poleski, M T Penny, E Kerins, I McDonald, Chung-Uk Lee, A Udalski, I A Bond, Y Shvartzvald, Weicheng Zang, R A Street, D W Hogg, B S Gaudi, T Barclay, G Barentsen, S B Howell, F Mullally, C B Henderson, S T Bryson, D A Caldwell, M R Haas, J E Van Cleve, K Larson, K McCalmont, C Peterson, D Putnam, S Ross, M Packard, L Reedy, Michael D Albrow, Sun-Ju Chung, Youn Kil Jung, Andrew Gould, Cheongho Han, Kyu-Ha Hwang, Yoon-Hyun Ryu, In-Gu Shin, Hongjing Yang, Jennifer C Yee, Sang-Mok Cha, Dong-Jin Kim, Seung-Lee Kim, Dong-Joo Lee, Yongseok Lee, Byeong-Gon Park, Richard W Pogge, M K Szymański, I Soszyński, K Ulaczyk, P Pietrukowicz, Sz Kozłowski, J Skowron, P Mróz, Shude Mao, Pascal Fouqué, Wei Zhu, F Abe, R Barry, D P Bennett, A Bhattacharya, A Fukui, H Fujii, Y Hirao, Y Itow, R Kirikawa, I Kondo, N Koshimoto, Y Matsubara, S Matsumoto, S Miyazaki, Y Muraki, G Olmschenk, C Ranc, A Okamura, N J Rattenbury, Y Satoh, T Sumi, D Suzuki, S I Silva, T Toda, P J Tristram, A Vandorou, H Yama, C Beichman, G Bryden, and S Calchi Novati
Published: 2023
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7. Precision Measurement of a Brown Dwarf Mass in A Binary System in the Microlensing Event OGLE-2019-BLG-0033/MOA-2019-BLG-035

Author: A. Herald, A. Udalski, V. Bozza, P. Rota, I. A. Bond, J. C. Yee, S. Sajadian, P. Mróz, R. Poleski, J. Skowron, M. K. Szymanski, I. Soszynski, P. Pietrukowicz, S. Kozłowsk, K. Ulaczyk, K. A. Rybicki, P. Iwanek, M. Wrona, M. Gromadzk, F. Abe, R. Barry, D. P. Bennett, A. Bhattacharya, A. Fukui, H. Fujii, Y. Hirao, Y. Itow, R. Kirikawa, I. Kondo, N. Koshimoto, Y. Matsubara, S. Matsumoto, S. Miyazaki, and Y. Muraki
Subjects: Astronomy, Astrophysics
Abstract: Context. Brown dwarfs are transition objects between stars and planets that are still poorly understood, for which several competing mechanisms have been proposed to describe their formation. Mass measurements are generally difficult to carry out for isolated objects as well as for brown dwarfs orbiting low-mass stars, which are often too faint for a spectroscopic follow-up. Aims. Microlensing provides an alternative tool for the discovery and investigation of such faint systems. Here, we present an analysis of the microlensing event OGLE-2019-BLG-0033/MOA-2019-BLG-035, which is caused by a binary system composed of a brown dwarf orbiting a red dwarf. Methods. Thanks to extensive ground observations and the availability of space observations from Spitzer, it has been possible to obtain accurate estimates of all microlensing parameters, including the parallax, source radius, and orbital motion of the binary lens. Results. Following an accurate modeling process, we found that the lens is composed of a red dwarf with a mass of M(1) = 0:149 ± 0.010 M⊙� and a brown dwarf with a mass of M(2) = 0:0463 ± 0:0031 M� at a projected separation of a⊥ = 0:585 au. The system has a peculiar velocity that is typical of old metal-poor populations in the thick disk. A percent-level precision in the mass measurement of brown dwarfs has been achieved only in a few microlensing events up to now, but will likely become more common in the future thanks to the Roman space telescope.
Published: 2022
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8. OGLE-2017-BLG-1186: first application of asteroseismology and Gaussian processes to microlensing

Author: S-S Li, W Zang, A Udalski, Y Shvartzvald, D Huber, C-U Lee, T Sumi, A Gould, S Mao, P Fouqué, T Wang, S Dong, U G Jørgensen, A Cole, P Mróz, M K Szymański, J Skowron, R Poleski, I Soszyński, P Pietrukowicz, S Kozłowski, K Ulaczyk, K A Rybicki, P Iwanek, J C Yee, S Calchi Novati, C A Beichman, G Bryden, S Carey, B S Gaudi, C B Henderson, W Zhu, M D Albrow, S-J Chung, C Han, K-H Hwang, Y K Jung, Y-H Ryu, I-G Shin, S-M Cha, D-J Kim, H-W Kim, S-L Kim, D-J Lee, Y Lee, B-G Park, R W Pogge, I A Bond, F Abe, R Barry, D P Bennett, A Bhattacharya, M Donachie, A Fukui, Y Hirao, Y Itow, I Kondo, N Koshimoto, M C A Li, Y Matsubara, Y Muraki, S Miyazaki, M Nagakane, C Ranc, N J Rattenbury, H Suematsu, D J Sullivan, D Suzuki, P J Tristram, A Yonehara, G Christie, J Drummond, J Green, S Hennerley, T Natusch, I Porritt, E Bachelet, D Maoz, R A Street, Y Tsapras, V Bozza, M Dominik, M Hundertmark, N Peixinho, S Sajadian, M J Burgdorf, D F Evans, R Figuera Jaimes, Y I Fujii, L K Haikala, C Helling, T Henning, T C Hinse, L Mancini, P Longa-Peña, S Rahvar, M Rabus, J Skottfelt, C Snodgrass, J Southworth, E Unda-Sanzana, C von Essen, J-P Beaulieu, J Blackman, and K Hill
Published: 2019
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9. Effect on Physical Functions of Older Adults When Refraining from Going out due to COVID-19 Restrictions

Author: S. Suzumura, K. Ito, R. Narukawa, E. Takano, K. Satoh, T. Ueda, and I. Kondo
Subjects: Geriatrics and Gerontology, Gerontology
Published: 2022
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10. Water‐level drawdowns can improve surface water quality and alleviate bottom hypoxia in shallow, eutrophic water bodies

Author: Shin‐ichiro S. Matsuzaki, Ayato Kohzu, Kenji Tsuchiya, Ryuichiro Shinohara, Megumi Nakagawa, Kayoko Fukumori, Haruyo Yamaguchi, Natsuko I. Kondo, and Taku Kadoya
Subjects: Aquatic Science
Published: 2022
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11. OGLE-2013-BLG-0911Lb: A Secondary on the Brown-dwarf Planet Boundary around an M Dwarf

Author: Shota Miyazaki, Takahiro Sumi, David P. Bennett, Andrzej Udalski, Yossi Shvartzvald, Rachel Street, Valerio Bozza, Jennifer C. Yee, Ian A. Bond, Nicholas Rattenbury, Naoki Koshimoto, Daisuke Suzuki, Akihiko Fukui, F. Abe, A. Bhattacharya, R. Barry, M. Donachie, H. Fujii, Y. Hirao, Y. Itow, Y. Kamei, I. Kondo, M. C. A. Li, C. H. Ling, Y. Matsubara, T. Matsuo, Y. Muraki, M. Nagakane, K. Ohnishi, C Ranc, T. Saito1, A. Sharan, H. Shibai, H. Suematsu, D. J. Sullivan, P. J. Tristram, T. Yamakawa, A. Yonehara, J. Skowron, R. Poleski, P. Mróz, M. K. Szymański, I. Soszyński, P. Pietrukowicz, S. KozŁowski, K. Ulaczyk, Ł. Wyrzykowski, Matan Friedmann, Shai Kaspi, Dan Maoz, M. Albrow, G. Christie, D. L. DePoy, A. Gal-Yam, A. Gould, C.-U. Lee, I. Manulis, J. McCormick, T. Natusch, H. Ngan, R. W. Pogge, I. Porritt, Y. Tsapras, E. Bachelet, M. P. G. Hundertmark, M. Dominik, D. M. Bramich, A. Cassan, R. Figuera Jaimes, K. Horne, R. Schmidt, C. Snodgrass, J. Wambsganss, I. A. Steele, J. Menzies, S. Mao, U. G. Jørgensen, M. J. Burgdorf, S. Ciceri, S. Calchi Novati, G. D’Ago, D. F. Evans, T. C. Hinse, N. Kains, E. Kerins, H. Korhonen, L. Mancini, A. Popovas, M. Rabus, S. Rahvar, G. Scarpetta, J. Skottfelt, J. Southworth, N. Peixinho, and P. Verma
Subjects: Astrophysics, Astronomy
Abstract: We present the analysis of the binary-lens microlensing event OGLE-2013-BLG-0911. The best-fit solutions indicate the binary mass ratio of q 0.03, which differs from that reported in Shvartzvald et al. The event suffers from the well-known close/wide degeneracy, resulting in two groups of solutions for the projected separation normalized by the Einstein radius of s ~ 0.15 or s ~ 7. The finite source and the parallax observations allow us to measure the lens physical parameters. The lens system is an M dwarf orbited by a massive Jupiter companion at very close (M(host) = 0.30(sup +0.08, sub -0.06)Mʘ, M(comp) = 10.1 (sup +2.9, sub -2.2 M(jup), a(exp) = 0.40 (sup +0.05, sub -0.40)au) or wide (M(host) = 0.28 (sup +0.10, sub -0.80)Mʘ, M(comp) = 9.9 (sup +3.8, sub -3.5)M(jup), a(exp) = 18.0 (sup +3.2, sub -3.2)au) separation. Although the mass ratio is slightly above the planet-brown dwarf (BD) mass-ratio boundary of q = 0.03, which is generally used, the median physical mass of the companion is slightly below the planet-BD mass boundary of 13M(Jup). It is likely that the formation mechanisms for BDs and planets are different and the objects near the boundaries could have been formed by either mechanism. It is important to probe the distribution of such companions with masses of ~13M(Jup) in order to statistically constrain the formation theories for both BDs and massive planets. In particular, the microlensing method is able to probe the distribution around low-mass M dwarfs and even BDs, which is challenging for other exoplanet detection methods.
Published: 2020
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12. Effect of titanium interlayers on adhesion enhancement of platinum films on titanium oxide films and on temperature coefficient of resistivity of platinum films

Author: I. Kondo, A. Takahashi, M. Shirai, K. Kondo, O. Takenaka, E. Kusano, and A. Kinbara
Published: 2023
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13. Relationships among Grip Strength Measurement, Response Time, and Frailty Criteria

Author: Y. Suzuki, Y. Matsui, Y. Hirano, I. Kondo, T. Nemoto, M. Tanimoto, and H. Arai
Subjects: General Medicine
Published: 2023
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14. Fine‐scale population fragmentation of a grassland butterfly <scp> Plebejus argyrognomon </scp> inhabiting agricultural field margin and riverbank in rural landscapes

Author: Hidenori Deto, Tatsuya Imai, Natsuko I. Kondo, Tadashi Miyashita, and Fuga Matsui
Subjects: geography, Population fragmentation, Habitat fragmentation, geography.geographical_feature_category, biology, Ecology, business.industry, Endangered species, biology.organism_classification, Grassland, Agriculture, Insect Science, Butterfly, Genetic structure, business, Ecology, Evolution, Behavior and Systematics, Plebejus argyrognomon
Published: 2021
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15. Impact of the Coronavirus Disease 2019 Outbreak on Activity and Exercise Levels among Older Patients

Author: N. Itoh, A. Osawa, M. Kamiya, K. Maki, Hidenori Arai, I. Kondo, K. Kawamura, S. Suzumura, I. Ueda, and Shinichiro Maeshima
Subjects: Male, medicine.medical_specialty, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), 030309 nutrition & dietetics, Frail Elderly, medicine.medical_treatment, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Physical activity, Medicine (miscellaneous), frailty, Disease Outbreaks, 03 medical and health sciences, Nursing care, 0302 clinical medicine, Older patients, Internal medicine, medicine, Humans, 030212 general & internal medicine, Exercise, Aged, Aged, 80 and over, 0303 health sciences, Nutrition and Dietetics, Rehabilitation, SARS-CoV-2, business.industry, activity, COVID-19, Outbreak, older patients, Brief Reports, Female, Geriatrics and Gerontology, nursing care, business, human activities
Abstract: OBJECTIVES: This study aimed to clarify the impact of the coronavirus disease 2019 outbreak on the levels of activity among older patients with frailty or underlying diseases. A total of 175 patients (79.0±7.0 years) undergoing outpatient or home-based rehabilitation, stratified into groups, based on frailty status. The percentage of patients who went out at least once a week decreased after the outbreak from 91% to 87%, from 65% to 46%, and from 47% to 36% in the non-frail, frail, and nursing care requirement groups, respectively. The proportion of older patients participating in exercise during the outbreak was 75%, 51%, and 41% in the non-frail, frail, and nursing care requirement groups, respectively. The proportion of older patients participating in voluntary exercise after instruction was lowest in the frail group (35%). Older patients with frailty are susceptible to the negative effects of refraining from physical activity and require careful management.
Published: 2021
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16. Well-Posedness for a Coupled System of Kawahara/KdV Type Equations

Author: Cezar I. Kondo and Ronaldo B. Pes
Subjects: 0209 industrial biotechnology, Control and Optimization, Wave propagation, Applied Mathematics, 010102 general mathematics, Mathematics::Analysis of PDEs, Physical system, 02 engineering and technology, Type (model theory), 01 natural sciences, Stability (probability), Nonlinear system, 020901 industrial engineering & automation, Initial value problem, Applied mathematics, 0101 mathematics, Contraction principle, Korteweg–de Vries equation, Mathematics
Abstract: We consider the initial value problem (IVP) associated to a coupled system of Kawahara/KdV type equations. We prove the well-posedness results for given data in a Gevrey spaces. The proof relies on estimates in space-time norms adapted to the linear part of the equations. In particular, estimates in Bourgain spaces are proven for the linear and nonlinear terms of the system and the main result is obtained by a contraction principle. The class of system in view contains a number of systems arising in the modeling of waves in fluids, stability and instability of solitary waves and models for wave propagation in physical systems where both nonlinear and dispersive effects are important. The techniques presented in this work were based in Grujic and Kalisch, who studied the Gevrey regularity for a class of water-wave models and the well-posedness of a IVP associated to a general equation, whose the initial data belongs to Gevrey spaces.
Published: 2021
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17. Existence of traveling waves for diffusive-dispersive conservation laws

Author: Cezar I. Kondo and Alex F. Rossini
Subjects: Scalar conservation law, diffusive-dispersive, weak solution, traveling wave, phase portrait, Mathematics, QA1-939
Abstract: In this work we show the existence existence and uniqueness of traveling waves for diffusive-dispersive conservation laws with flux function in $C^{1}(mathbb{R})$, by using phase plane analysis. Also we estimate the domain of attraction of the equilibrium point attractor corresponding to the right-hand state. The equilibrium point corresponding to the left-hand state is a saddle point. According to the phase portrait close to the saddle point, there are exactly two semi-orbits of the system. We establish that only one semi-orbit come in the domain of attraction and converges to $(u_{-},0)$ as $yo -infty$. This provides the desired saddle-attractor connection.
Published: 2013

18. Habitat characteristics and size structure in a population of an endangered lamprey, Lethenteron sp. N, in an urbanized area of Japan

Author: Jun Nishihiro, Noriko Kidera, Natsuko I. Kondo, and Yuna Hirano
Subjects: 0106 biological sciences, Lethenteron, education.field_of_study, biology, Ecology, Lamprey, Population, Endangered species, 04 agricultural and veterinary sciences, biology.organism_classification, Spatial distribution, 010603 evolutionary biology, 01 natural sciences, Substrate (marine biology), Habitat, Abundance (ecology), 040102 fisheries, 0401 agriculture, forestry, and fisheries, education, Ecology, Evolution, Behavior and Systematics
Abstract: For conservation of a lamprey population in an urbanized area, basic properties including taxonomic attribution, habitat characteristics and spatial distribution were investigated. Sequencing analysis of mitochondrial genes suggested that the population belongs to Lethenteron sp. N. The abundance and size distribution of the population varied temporally and spatially. Spawning activity was observed only in the uppermost reach. Although a drop structure at the downstream may prevent the movement of individuals, the presence of many sources of spring water and sandy substrate in the study stream suggested that the local condition of habitat was suitable for this species.
Published: 2020
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19. Apolipoprotein B, Residual Cardiovascular Risk After Acute Coronary Syndrome, and Effects of Alirocumab

Author: Emil Hagström, P. Gabriel Steg, Michael Szarek, Deepak L. Bhatt, Vera A. Bittner, Nicolas Danchin, Rafael Diaz, Shaun G. Goodman, Robert A. Harrington, J. Wouter Jukema, Evangelos Liberopoulos, Nikolaus Marx, Jennifer McGinniss, Garen Manvelian, Robert Pordy, Michel Scemama, Harvey D. White, Andreas M. Zeiher, Gregory G. Schwartz, Pierluigi Tricoci, Matthew T. Roe, Kenneth W. Mahaffey, Jay M. Edelberg, Corinne Hanotin, Guillaume Lecorps, Angèle Moryusef, William J. Sasiela, Jean-François Tamby, Philip E Aylward, Heinz Drexel, Peter Sinnaeve, Mirza Dilic, Renato D. Lopes, Nina N Gotcheva, Juan-Carlos Prieto, Huo Yong, Patricio López-Jaramillo, Ivan Pećin, Zeljko Reiner, Petr Ostadal, Steen Hvitfeldt Poulsen, Margus Viigimaa, Markku S Nieminen, Vakhtang Chumburidze, Pablo Carlos, Montenegro Valdovinos, Hung-Fat Tse, Robert Gabor Kiss, Denis Xavier, Doron Zahger, Marco Valgimigli, Takeshi Kimura, Hyo Soo Kim, Sang-Hyun Kim, Andrejs Erglis, Aleksandras Laucevicius, Sasko Kedev, Khalid Yusoff, Gabriel Arturo Ramos López, Marco Alings, Sigrun Halvorsen, Roger M Correa Flores, Rody G. Sy, Andrzej Budaj, Joao Morais, Maria Dorobantu, Yuri Karpov, Arsen D. Ristic, Terrance Chua, Jan Murin, Zlatko Fras, Anthony J Dalby, José Tuñón, H. Asita de Silva, Ulf Landmesser, Christian Müller, Chern-En Chiang, Piyamitr Sritara, Sema Guneri, Alexander Parkhomenko, Kausik K. Ray, Patrick M. Moriarty, Robert Vogel, Bernard Chaitman, Sheryl F. Kelsey, Anders G. Olsson, Jean-Lucien Rouleau, Maarten L. Simoons, Karen Alexander, Chiara Meloni, Robert Rosenson, Eric J.G. Sijbrands, John H. Alexander, Luciana Armaganijan, Akshay Bagai, Maria Cecilia Bahit, J. Matthew Brennan, Shaun Clifton, Adam D. DeVore, Shalonda Deloatch, Sheila Dickey, Keith Dombrowski, Grégory Ducrocq, Zubin Eapen, Patricia Endsley, Arleen Eppinger, Robert W. Harrison, Connie Ng Hess, Mark A. Hlatky, Joseph Dedrick Jordan, Joshua W. Knowles, Bradley J. Kolls, David F. Kong, Sergio Leonardi, Linda Lillis, David J. Maron, Jill Marcus, Robin Mathews, Rajendra H. Mehta, Robert J. Mentz, Humberto Graner Moreira, Chetan B. Patel, Sabrina Bernardez Pereira, Lynn Perkins, Thomas J. Povsic, Etienne Puymirat, William Schuyler Jones, Bimal R. Shah, Matthew W. Sherwood, Kenya Stringfellow, Darin Sujjavanich, Mustafa Toma, Charlene Trotter, Sean F.P. van Diepen, Matthew D. Wilson, Andrew Tze-Kay Yan, Lilia B Schiavi, Marcelo Garrido, Andrés F Alvarisqueta, Sonia A Sassone, Anselmo P Bordonava, Alberto E Alves De Lima, Jorge M Schmidberg, Ernesto A Duronto, Orlando C Caruso, Leonardo P Novaretto, Miguel Angel Hominal, Oscar R Montaña, Alberto Caccavo, Oscar A Gomez Vilamajo, Alberto J Lorenzatti, Luis R Cartasegna, Gustavo A Paterlini, Ignacio J Mackinnon, Guillermo D Caime, Marcos Amuchastegui, Oscar Salomone, Oscar R Codutti, Horacio O Jure, Julio OE Bono, Adrian D Hrabar, Julio A Vallejos, Rodolfo A Ahuad Guerrero, Federico Novoa, Cristian A Patocchi, Cesar J Zaidman, Maria E Giuliano, Ricardo D Dran, Marisa L Vico, Gabriela S Carnero, Pablo N Guzman, Juan C Medrano Allende, Daniela F Garcia Brasca, Miguel H Bustamante Labarta, Sebastian Nani, Eduardo DS Blumberg, Hugo R Colombo, Alberto Liberman, Victorino Fuentealba, Hector L Luciardi, Gabriel D Waisman, Mario A Berli, Ruben O Garcia Duran, Horacio G Cestari, Hugo A Luquez, Jorge A Giordano, Silvia S 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Blok, William Sheldon, Masoud M Azizad, Carsten Schmalfuss, Mark Picone, Robert Pederson, William Herzog, Keith Friedman, Jason Lindsey, Eichenlaub Timothy, Parilak Leonard, Norman Lepor, Mahfouz El Shahawy, Howard Weintraub, Anand Irimpen, Alvaro Alonso, Wade May, Daniels Christopher, Thomas Galski, Alan Chu, Freny Mody, Ebrahimi Ramin, Zachary Hodes, Joseph Rossi, Gregory Rose, James Fairlamb, Charles Lambert, Ajit Raisinghani, Antonio Abbate, George Vetrovec, Marilyn King, Charles Carey, Jaime Gerber, Liwa Younis, Hyeun (Tom) Park, Mladen Vidovich, Thomas Knutson, Dennis Friedman, Fred Chaleff, Arthur Loussararian, Phillip Rozeman, Carey Kimmelstiel, Jeffrey Kuvin, Kevin Silver, Malcolm Foster, Glen Tonnessen, Andrey Espinoza, Mohamadali Amlani, Andreas Wali, Christopher Malozzi, Geert T Jong, Clara Massey, Keattiyoat Wattanakit, Philip J. O’Donnell, Dinesh Singal, Naseem Jaffrani, Sridhar Banuru, Daniel Fisher, Mark Xenakis, Neal Perlmutter, Ravi Bhagwat, James Strader, Ronald Blonder, Ayim Akyea-Djamson, Ajay Labroo, Kwan Lee, H. John Marais, Edmund Claxton, Robert Weiss, Rohr Kathryn, Martin Berk, Peter Rossi, Parag Joshi, Amit Khera, Ajit S Khaira, Greg Kumkumian, Steven Lupovitch, Joshua Purow, Stephen Welka, David Hoffman, Stuart Fischer, Eugene Soroka, Donald Eagerton, Samir Pancholy, Michael Ray, Norman Erenrich, Michael Farrar, Stewart Pollock, William J French, Steve Diamantis, Douglas Guy, Lawrence Gimple, Mark Neustel, Steven Schwartz, Edward Pereira, Seals Albert, Douglas Spriggs, Janet Strain, Suneet Mittal, Anthony Vo, Majed Chane, Jason Hall, Nampalli Vijay, Kapildeo Lotun, F. Martin Lester, Ahed Nahhas, Theodore Pope, Paul Nager, Rakesh Vohra, Mukesh Sharma, Riyaz Bashir, Hinan Ahmed, Michael Berlowitz, Robert Fishberg, Robert Barrucco, Eric Yang, Michael Radin, Daniel Sporn, Dwight Stapleton, Steven Eisenberg, Joel Landzberg, Martin Mcgough, Samir Turk, Michael Schwartz, P. Sandy Sundram, Diwakar Jain, Mark Zainea, Carlos Bayron, Ronald Karlsberg, Suhail Dohad, Henry Lui, William Keen, Donald Westerhausen, Sandeep Khurana, Himanshu Agarwal, Jessica Birchem, William Penny, Mark Chang, Sherrill Murphy, John Henry, Branislav Schifferdecker, John M Gilbert, Gopal Chalavarya, Charles Eaton, John F Schmedtje, Stuart Christenson, Imran Dotani, Douglas Denham, Alexander Macdonell, Paul Gibson, Aref Rahman, Tammam Al Joundi, Nizar Assi, Gary Conrad, Purushotham Kotha, Michael Love, Gregory Giesler, Howard Rubenstein, Dawood Gamil, Laura Akright, Justine Krawczyk, Joanne Cobler, Terry Wells, James Welker, Robert Foster, Richard Gilmore, Jay Anderson, Douglas Jacoby, Bill Harris, Geraldine Gardner, Ramprasad Dandillaya, Kishor Vora, John Kostis, John Hunter, David Laxson, Eric Ball, Flavia Egydio, Anelise Kawakami, Janaina Oliveira, Julianna Wozniak, Alexander Matthews, Caroline Ratky, Janine Valiris, Lisa Berdan, Anita Hepditch, Kirby Quintero, Tyrus Rorick, Melissa Westbrook, Madeleine Bezault, Elodie Drouet, Tabassome Simon, Caroline Alsweiler, Anne Luyten, Julie Butters, Liddy Griffith, Michelle Shaw, Lena Grunberg, Shahidul Islam, Marie-France Brégeault, Nathalie Bougon, Douglas Faustino, Sylvie Fontecave, Judith Murphy, Jean- Francois Tamby, Melanie Verrier, Veronique Agnetti, Dorthe Andersen, Emmy Badreddine, Mhamed Bekkouche, Cecile Bouancheau, Imane Brigui, Maddy Brocklehurst, Joseph Cianciarulo, Dawn Devaul, Szilvia Domokos, Cecile Gache, Caroline Gobillot, Severine Guillou, Jan Healy, Megan Heath, Gayatri Jaiwal, Carine Javierre, Julien Labeirie, Myriam Monier, Ulises Morales, Asmaa Mrabti, Bicky Mthombeni, Betim Okan, Lucile Smith, Jennifer Sheller, Sebastien Sopena, Valerie Pellan, Fadela Benbernou, Nafissa Bengrait, Maud Lamoureux, Katarina Kralova, Raphael Bejuit, Anthony Coulange, Christelle Berthou, Jérôme Repincay, Christelle Lorenzato, Alexis Etienne, Valerie Gouet, Virginie Loizeau, Mickael Normand, Anne Ourliac, Christelle Rondel, Antony Adamo, Pascale Beltran, Pauline Barraud, Helene Dubois-Gache, Benjamin Halle, Lamia Metwally, Maxime Mourgues, Marc Sotty, Marion Vincendet, Raluca Cotruta, Zhu Chengyue, Dominique Fournie-Lloret, Christine Morrello, Aurelie Perthuis, Patrick Picault, Isabelle Zobouyan, Helen M. 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McClanahan, Roe, Matthew T., Blicharski, Tomasz, Bystryk, Leszek, Szpajer, Michal, Korol, Marek, Czerski, Tomasz, Gniot, Jacek, Lubinski, Andrzej, Gorny, Jerzy, Franek, Edward, Raczak, Grzegorz, Vogel, Robert, Szwed, Hanna, Monteiro, Pedro, Mesquita Bastos, Jose, Pereira, Helder H., Morais, Joao, Seixo, Filipe, Mendonça, Carlos, Botelho, Ana, Caetano, Francisca, Minescu, Bogdan, Chaitman, Bernard, Istratoaie, Octavian, Tesloianu, Dan N., Dorobantu, Maria, Cristian, Gabriel, Dumitrescu, Silviu, Podoleanu, Cristian Gc, Constantinescu, Mircea Ca, Bengus, Cristina M., Militaru, Constantin, Rosu, Doina, Kelsey, Sheryl F., Parepa, Irinel R., Matei, Adrian V., Alexandru, Tom M., Malis, Mihaela, Coman, Ioan, Shvarts, Yury, Orlikova, Olga, Kobalava, Zhanna, Barbarash, Olga L., Markov, Valentin, Olsson, Anders G., Lyamina, Nadezhda, Gordienko, Alexander, Zrazhevsky, Konstantin, Vishnevsky, Alexander Y., Gurevich, Victor, Stryuk, Raisa, Lomakin, Nikita V., Bokarev, Igor, Khlevchuk, Tatiana, Shalaev, Sergey, Rouleau, Jean-Lucien, Khaisheva, Larisa, Chizhov, Petr, Viktorova, Inna, Osokina, Natalya, Shchekotov, Vladimir, Akatova, Evgenia, Chumakova, Galina, Libov, Igor, Voevoda, Mikhail I., Tretyakova, Tatyana V., Simoons, Maarten L., Baranov, Evgeny, Shustov, Sergey, Yakushin, Sergey, Gordeev, Ivan, Khasanov, Niiaz, Reshetko, Olga, Sotnikova, Tatiana, Molchanova, Olga, Nikolaev, Konstantin, Gapon, Liudmila, Alexander, Karen, Baranova, Elena, Kosmachova, Elena, Karpov, Yuriy, Karpov, Yuri, Povzun, Anton, Egorova, Liudmila, Tyrenko, Vadim V., Ivanov, Igor G., Ilya, Masterov, Kanorsky, Sergey, Meloni, Chiara, Simic, Dragan, Ivanovic, Nikola, Davidovic, Goran, Tasic, Nebojsa, Asanin, Milika R., Stojic, Stevo, Apostolovic, Svetlana R., Ilic, Stevan, Tosic, Biljana Putnikovic, Stankovic, Aleksandar, Rosenson, Robert, Arandjelovic, Aleksandra, Radovanovic, Slavica, Todic, Branislava, Ristic, Arsen D., Balinovac, Jovan, Dincic, Dragan V., Seferovic, Petar, Karadzic, Ana, Dodic, Slobodan, Dimkovic, Sinisa, Sijbrands, Eric J. G., Jakimov, Tamara, Poh, Kian-Keong, Yee Ong, Hean, Tang I-Shing, Justin, Micko, Karol, Nociar, Jan, Pella, Daniel, Fulop, Peter, Hranai, Marian, Palka, Juraj, Tricoci, Pierluigi, Mazur, Juraj, Majercák, Ivan, Dzupina, Andrej, Fazekas, František, Gonsorcik, Jozef, Bugan, Viliam, Murin, Jan, Selecky, Juraj, Kamensky, Gabriel, Strbova, Jaroslava, Alexander, John H., Smik, Rudolf, Dukat, Andrej, Olexa, Peter, Žuran, Ivan, Poklukar, Janez, Šuligoj, Nataša Černič, Cevc, Matija, Fras, Zlatko, Cyster, Henry P., Ranjith, Naresh, Armaganijan, Luciana, Corbett, Clive, Bayat, Junaid, Makoali Makotoko, Ellen, du Toit Theron, Hendrik, Kapp, Ilse E., de V Basson, Matthys M., Lottering, Hanlie, Van Aswegen, Dina, Van Zyl, Louis J., Sebastian, Peter J., Bagai, Akshay, Pillay, Thayabran, Saaiman, Jan A., Commerford, Patrick J., Cassimjee, Soraya, Riaz, Garda, Ebrahim, Iftikhar O., Sarvan, Mahomed, Mynhardt, Joseph H., Dalby, Anthony J., Reuter, Helmuth, Bahit, Maria Cecilia, Moodley, Rajendran, Vida, Manuel, Fillat, Angel R. 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Matthew, Worner Diz, Fernando, Garcia-Dorado, David, Iñiguez, Andres, Gonzalez-Juanatey, Jose R., Portales, Javier Fernandez, Murillo, Fernando Civeira, Pericas, Laia Matas, Zamorano, Jose Luis, De Mora Martin, Manuel, Cortada, Jordi Bruguera, Clifton, Shaun, Alonso Martin, Joaquin J., Serrano Antolin, Jose Maria, De Berrazueta Fernández, José R., Vázquez de Prada, José Antonio, Díaz Fernández, Jose Francisco, García Lledó, José Alberto, Cosín Sales, Juan, Rodriguez, Javier Botas, Tragant, Gabriel Gusi, Benedicto, Amparo, DeVore, Adam D., Gonzalez-Juanatey, Carlos, Camprubí Potau, Mercedes, Perez, Ignacio Plaza, De La Tassa, César Morís, Rincon, Pablo Loma-Osorio, Recena, Javier Balaguer, Escudier, Juan M., Payeras, Antonio Coca, Orcajo, Norberto Alonso, Constantine, Godwin, Deloatch, Shalonda, Haniffa, Ruvaiz, Tissera, Nirmali, Amarasekera, Stanley, Ponnamperuma, Chandrike, Fernando, Nimali, Fernando, Kaputella, Jayawardena, Jayanthimala, Wijeyasingam, Santharaj, Ranasinghe, Gotabhaya, Ekanayaka, Ruvan, Dickey, Sheila, Mendis, Sepalika, Senaratne, Vajira, Mayurathan, Gnanamoorthy, Rajapaksha, Ajantha, Sirisena, Thilak, Herath, Jagath I., Amarasena, Naomali, Berglund, Stefan, Rasmanis, Gundars, Hagström, Emil, Dombrowski, Keith, Vedin, Ola, Witt, Nils, Mourtzinis, Georgios, Nicol, Peter, Hansen, Ole, Romeo, Stefano, Jensen, Steen Agergaard, Torstensson, Ingemar, Ahremark, Ulf, Sundelin, Torbjörn, Ducrocq, Grégory, Moccetti, Tiziano, Müller, Christian, Mach, Francois, Binde, Ronald, Landmesser, Ulf, Gämperli, Oliver, Chiang, Chern-En, Tsai, Wei-Chuan, Ueng, Kwo-Chang, Lai, Wen-Ter, Eapen, Zubin, Liu, Ming-En, Hwang, Juey-Jen, Yin, Wei-Hsian, Hsieh, I.-Chang, Hsieh, Ming-Jer, Hsiang Lin, Wei, Kuo, Jen-Yuan, Huang, Tsuei-Yuan, Fang, Chih-Yuan, Kaewsuwanna, Pinij, Endsley, Patricia, Soonfuang, Wasant, Jintapakorn, Woravut, Sukonthasarn, Apichard, Sritara, Piyamitr, Wongpraparut, Nattawut, Sastravaha, Krisada, Sansanayudh, Nakarin, Kehasukcharoen, Wirash, Piyayotai, Dilok, Chotnoparatpat, Paiboon, Eppinger, Arleen, Camsari, Ahmet, Kultursay, Hakan, Guneri, Sema, Mutlu, Bulent, Ersanli, Murat, Demirtas, Mustafa, Kirma, Cevat, Ural, Ertan, Koldas, Lale, Karpenko, Oleksandr, Harrison, Robert W., Prokhorov, Alexander, Vakaluyk, Ihor, Myshanych, Halyna, Reshotko, Dmytro, Batushkin, Valeriy, Rudenko, Leonid, Kovalskyi, Ihor, Kushnir, Mykola, Tseluyko, Vira, Mostovoy, Yuriy, Hess, Connie Ng, Stanislavchuk, Mykola, Kyiak, Yulian, Karpenko, Yuriy, Malynovsky, Yaroslav, Klantsa, Andriy, Kutniy, Oles, Amosova, Ekaterina, Tashchuk, Viktor, Leshchuk, Oleh, Parkhomenko, Alexander, Hlatky, Mark A., Rishko, Mykola, Kopytsya, Mykola, Yagensky, Andriy, Vatutin, Mykola, Bagriy, Andriy, Barna, Olga M., Ushakov, Olexiy, Dzyak, Georgiy, Goloborodko, Borys, Rudenko, Anatolii, Jordan, Joseph Dedrick, Zheleznyy, Volodymyr, Trevelyan, Jasper, Zaman, Azfar, Lee, Kaeng, Moriarty, Andrew, Aggarwal, Rajesh K., Clifford, Piers, Wong, Yuk-ki, Iqbal, Syed Mr, Subkovas, Eduardas, Knowles, Joshua W., Braganza, Denise, Sarkar, David, Storey, Robert, Griffiths, Huw, Mcclure, Sam, Muthusamy, Rangasamy, Smith, Simon, Kurian, John, Levy, Terry, Barr, Craig, Kolls, Bradley J., Kadr, Honer, Gerber, Robert, Simaitis, Audrius, Soran, Handrean, Brodison, Adrian, Ayaz, Mohammad, Cheema, Muhammad, Oliver, Richard, Thackray, Simon, Mudawi, Telal, Kong, David F., Rahma, Gohar, Sultan, Ayyaz, Reynolds, Timothy, Sharman, David, Spriging, David, Butler, Rob, Wilkinson, Peter, Lip, Gregory Yh, Ossei-Gerning, Nicholas, Vardi, Gil, Leonardi, Sergio, Baldari, Duccio, Brabham, David, Treasure Ii, Charles, Dahl, Charles, Palmer, Bruce, Wiseman, Alan, Khan, Abul, Puri, Sanjeev, Mohart, Ann Elizabeth, Ince, Carlos, Lillis, Linda, Flores, Enrique, Wright, Scott, Cheng, Shi-Chi, Rosenberg, Michael, Rogers, William, Kosinski, Edward, Forgosh, Les, Waltman, Jonathan, Shoukfeh, Mohammad, Dagher, Georges, Lopes, Renato D., Cambier, Patrick, Lieber, Ira, Kumar, Priya, East, Cara, Krichmar, Perry, Hasan, Mian, White, Lindsey, Knickelbine, Thomas, Haldis, Thomas, Gillespie, Eve, Maron, David J., Amidon, Thomas, Suh, David, Arif, Imran, Abdallah, Mouhamad, Akhter, Faiq, Carlson, Eric, D'Urso, Michael, El-Ahdab, Fadi, Nelson, William, Moriarty, Katie, Mahaffey, Kenneth W., Harris, Barry, Cohen, Steven, Carter, Luther, Doty, Daniel, Sabatino, Kenneth, Haddad, Tariq, Rao, Sunder, Mulkay, Angel, Jovin, Ion, Klancke, Kim, Marcus, Jill, Malhotra, Vinay, Devarapalli, Sai K., Koren, Michael, Chandna, Harish, Dodds Iii, George, Goraya, Tauqir, Bengston, James, Janik, Matthew, Moran, Joseph, Sumner, Andrew, Mathews, Robin, Kobayashi, John, Davis, William, Yazdani, Shahram, Pasquini, John, Thakkar, Maitreya, Vedere, Amarnath, Leimbach, Wayne, Rider, James, Fenton, Sarah, Singh, Narendra, Mehta, Rajendra H., Shah, Anil V., Moriarty, Patrick M., Janosik, Denise, Pepine, Carl, Berman, Brett, Gelormini, Joseph, Daniels, Christopher, Richard, Kerensky, Keating, Friederike, Kondo, Nicholas I., Mentz, Robert J., Shetty, Sanjay, Levite, Howard, Waider, Winfried, Takata, Theodore, Abu-Fadel, Mazen, Shah, Vipul, Aggarwal, Rahul, Kumar, Anil, Hattler, Brack, Do, Rose, Moreira, Humberto Graner, Link, Chad, Bortnick, Anna, Kinzfogl Iii, George, Ghitis, Arnold, Larry, John, Teufel, Edward, Kuhlman, Peter, Mclaurin, Brent, Zhang, Wenwu, Thew, Stephen, Patel, Chetan B., Abbas, Jalal, White, Matthew, Islam, Othman, Subherwal, Sumeet, Ranadive, Nandkishore, Vakili, Babak, Gring, Christian, Henderson, David, Schuchard, Timothy, Farhat, Naim, Pereira, Sabrina Bernardez, Kline, Geoffrey, Mahal, Sharan, Whitaker, Jack, Speirs, Shawn, Andersen, Rolf, Daboul, Nizar, Horwitz, Phillip, Zahr, Firas, Ponce, George, Jafar, Zubair, Perkins, Lynn, Mcgarvey, Joseph, Panchal, Vipul, Voyce, Stephen, Blok, Thomas, Sheldon, William, Azizad, Masoud M., Schmalfuss, Carsten, Picone, Mark, Pederson, Robert, Herzog, William, Povsic, Thomas J., Friedman, Keith, Lindsey, Jason, Timothy, Eichenlaub, Leonard, Parilak, Lepor, Norman, El Shahawy, Mahfouz, Weintraub, Howard, Irimpen, Anand, Alonso, Alvaro, May, Wade, Puymirat, Etienne, Christopher, Daniels, Galski, Thomas, Chu, Alan, Mody, Freny, Ramin, Ebrahimi, Hodes, Zachary, Rossi, Joseph, Rose, Gregory, Fairlamb, James, Lambert, Charles, Raisinghani, Ajit, Abbate, Antonio, Vetrovec, George, King, Marilyn, Carey, Charles, Gerber, Jaime, Younis, Liwa, Park, Hyeun Tom, Vidovich, Mladen, Knutson, Thomas, Jones, William Schuyler, Friedman, Dennis, Chaleff, Fred, Loussararian, Arthur, Rozeman, Phillip, Kimmelstiel, Carey, Kuvin, Jeffrey, Silver, Kevin, Foster, Malcolm, Tonnessen, Glen, Espinoza, Andrey, Shah, Bimal R., Amlani, Mohamadali, Wali, Andreas, Malozzi, Christopher, Jong, Geert T., Massey, Clara, Wattanakit, Keattiyoat, O'Donnell, Philip J., Singal, Dinesh, Jaffrani, Naseem, Banuru, Sridhar, Sherwood, Matthew W., Fisher, Daniel, Xenakis, Mark, Perlmutter, Neal, Bhagwat, Ravi, Strader, James, Blonder, Ronald, Akyea-Djamson, Ayim, Labroo, Ajay, Lee, Kwan, Marais, H. John, Stringfellow, Kenya, Claxton, Edmund, Weiss, Robert, Kathryn, Rohr, Berk, Martin, Rossi, Peter, Joshi, Parag, Khera, Amit, Khaira, Ajit S., Kumkumian, Greg, Lupovitch, Steven, Sujjavanich, Darin, Purow, Joshua, Welka, Stephen, Hoffman, David, Fischer, Stuart, Soroka, Eugene, Eagerton, Donald, Pancholy, Samir, Ray, Michael, Erenrich, Norman, Farrar, Michael, Toma, Mustafa, Pollock, Stewart, French, William J., Diamantis, Steve, Guy, Douglas, Gimple, Lawrence, Neustel, Mark, Schwartz, Steven, Pereira, Edward, Albert, Seals, Spriggs, Douglas, Trotter, Charlene, Strain, Janet, Mittal, Suneet, Vo, Anthony, Chane, Majed, Hall, Jason, Vijay, Nampalli, Lotun, Kapildeo, Lester, F. Martin, Nahhas, Ahed, Pope, Theodore, van Diepen, Sean F. 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Pereira, Helder H, Tesloianu, Dan N, Bengus, Cristina M, Parepa, Irinel R, Matei, Adrian V, Alexandru, Tom M, Barbarash, Olga L, Vishnevsky, Alexander Y, Lomakin, Nikita V, Voevoda, Mikhail I, Tretyakova, Tatyana V, Tyrenko, Vadim V, Ivanov, Igor G, Asanin, Milika R, Apostolovic, Svetlana R, Dincic, Dragan V, Cyster, Henry P, Kapp, Ilse E, de V Basson, Matthys M, Aswegen, Dina Van, Van Zyl, Louis J, Sebastian, Peter J, Saaiman, Jan A, Commerford, Patrick J, Ebrahim, Iftikhar O, Mynhardt, Joseph H, Fillat, Angel R Cequier, Cruz Fernández, Jose M, Gonzalez-Juanatey, Jose R, Alonso Martin, Joaquin J, De Berrazueta Fernández, José R, Escudier, Juan M, Herath, Jagath I, Hsieh, I-Chang, Barna, Olga M, Aggarwal, Rajesh K, Wong, Yuk-Ki, Devarapalli, Sai K, Shah, Anil V, Kondo, Nicholas I, Azizad, Masoud M, Jong, Geert T, O'Donnell, Philip J, Marais, H John, Khaira, Ajit S, French, William J, Lester, F Martin, Sundram, P Sandy, Gilbert, John M, Schmedtje, John F, Colhoun, Helen M, Dempsey, Michael A, and McClanahan, Mark A
Subjects: Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use, Anticholesteremic Agents/adverse effects, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], prevention & control, heart disease risk factors, diagnosis [Cardiovascular Diseases], Antibodies, Monoclonal, Humanized, PCSK9 inhibitors, acute coronary syndrome, apolipoproteins B, LDL cholesterol, Antibodies, acute coronary syndrome, LDL, drug therapy [Atherosclerosis], Risk Factors, Physiology (medical), therapeutic use [Hydroxymethylglutaryl-CoA Reductase Inhibitors], Monoclonal, Humans, Cardiac and Cardiovascular Systems, Humanized, Cardiovascular Diseases/diagnosis, Apolipoproteins B, Kardiologi, diagnosis [Acute Coronary Syndrome], Anticholesteremic Agents, PCSK9 inhibitors, apolipoproteins B, cholesterol, LDL, cholesterol, Atherosclerosis/drug therapy, Cholesterol, LDL, Atherosclerosis, Acute Coronary Syndrome/diagnosis, drug therapy, Cholesterol, Treatment Outcome, Cardiovascular Diseases, Heart Disease Risk Factors, epidemiology, adverse effects [Anticholesteremic Agents], Hydroxymethylglutaryl-CoA Reductase Inhibitors, Cardiology and Cardiovascular Medicine
Abstract: Circulation : an official journal of the American Heart Association / ed.-in-chief Ephraim Donosco 146(9), 657-672 (2022). doi:10.1161/CIRCULATIONAHA.121.057807, Published by Ovid, [Erscheinungsort nicht ermittelbar]
Published: 2022
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20. Zero Diffusion-Dispersion Limits for Scalar Conservation Laws.

Author: Cezar I. Kondo and Philippe G. LeFloch
Published: 2002
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21. Lipoprotein(a) and Benefit of PCSK9 Inhibition in Patients With Nominally Controlled LDL Cholesterol

Author: Gregory G. Schwartz, Michael Szarek, Vera A. Bittner, Rafael Diaz, Shaun G. Goodman, J. Wouter Jukema, Ulf Landmesser, Patricio López-Jaramillo, Garen Manvelian, Robert Pordy, Michel Scemama, Peter R. Sinnaeve, Harvey D. White, Ph Gabriel Steg, P.h. Gabriel Steg, Deepak L. Bhatt, Robert A. Harrington, Andreas M. Zeiher, Pierluigi Tricoci, Matthew T. Roe, Kenneth W. Mahaffey, Jay M. Edelberg, Corinne Hanotin, Guillaume Lecorps, Angèle Moryusef, William J. Sasiela, Jean-François Tamby, Philip E. Aylward, Heinz Drexel, Peter Sinnaeve, Mirza Dilic, Renato D. Lopes, Nina N. Gotcheva, Juan-Carlos Prieto, Huo Yong, Ivan Pećin, Zeljko Reiner, Petr Ostadal, Steen Hvitfeldt Poulsen, Margus Viigimaa, Markku S. Nieminen, Nicolas Danchin, Vakhtang Chumburidze, Nikolaus Marx, Evangelos Liberopoulos, Pablo Carlos Montenegro Valdovinos, Hung-Fat Tse, Robert Gabor Kiss, Denis Xavier, Doron Zahger, Marco Valgimigli, Takeshi Kimura, Hyo Soo Kim, Sang-Hyun Kim, Andrejs Erglis, Aleksandras Laucevicius, Sasko Kedev, Khalid Yusoff, Gabriel Arturo Ramos López, Marco Alings, Sigrun Halvorsen, Roger M. Correa Flores, Rody G. Sy, Andrzej Budaj, Joao Morais, Maria Dorobantu, Yuri Karpov, Arsen D. Ristic, Terrance Chua, Jan Murin, Zlatko Fras, Anthony J. Dalby, José Tuñón, H. Asita de Silva, Emil Hagström, Christian Müller, Chern-En Chiang, Piyamitr Sritara, Sema Guneri, Alexander Parkhomenko, Kausik K. Ray, Patrick M. Moriarty, Robert Vogel, Bernard Chaitman, Sheryl F. Kelsey, Anders G. Olsson, Jean-Lucien Rouleau, Maarten L. Simoons, Karen Alexander, Chiara Meloni, Robert Rosenson, Eric J.G. Sijbrands, John H. Alexander, Luciana Armaganijan, Akshay Bagai, Maria Cecilia Bahit, J. Matthew Brennan, Shaun Clifton, Adam D. DeVore, Shalonda Deloatch, Sheila Dickey, Keith Dombrowski, Grégory Ducrocq, Zubin Eapen, Patricia Endsley, Arleen Eppinger, Robert W. Harrison, Connie Ng Hess, Mark A. Hlatky, Joseph Dedrick Jordan, Joshua W. Knowles, Bradley J. Kolls, David F. Kong, Sergio Leonardi, Linda Lillis, David J. Maron, Jill Marcus, Robin Mathews, Rajendra H. Mehta, Robert J. Mentz, Humberto Graner Moreira, Chetan B. Patel, Sabrina Bernardez Pereira, Lynn Perkins, Thomas J. Povsic, Etienne Puymirat, William Schuyler Jones, Bimal R. Shah, Matthew W. Sherwood, Kenya Stringfellow, Darin Sujjavanich, Mustafa Toma, Charlene Trotter, Sean F.P. van Diepen, Matthew D. Wilson, Andrew Tze-Kay Yan, Lilia B. Schiavi, Marcelo Garrido, Andrés F. Alvarisqueta, Sonia A. Sassone, Anselmo P. Bordonava, Alberto E. Alves De Lima, Jorge M. Schmidberg, Ernesto A. Duronto, Orlando C. Caruso, Leonardo P. Novaretto, Miguel Angel Hominal, Oscar R. Montaña, Alberto Caccavo, Oscar A. 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Abrantes, Pedro Pimentel Filho, Ana Priscila Soggia, Mayler O.N. de Santos, Fernando Neuenschwander, Luiz C. Bodanese, Yorghos L. Michalaros, Freddy G. Eliaschewitz, Maria H. Vidotti, Paulo E. Leaes, Roberto V. Botelho, Sergio Kaiser, Euler Roberto F. Fernandes Manenti, Dalton B. Precoma, Jose C. Moura Jorge, Pedro Silva, Jose A. Silveira, Wladmir Saporito, Jose A. Marin Neto, Gilson S. Feitosa, Luiz Eduardo F. Ritt, Juliana A. de Souza, Fernando Costa, Weimar K.S.B. Souza, Helder J.L. Reis, Leandro Machado, José Carlos Aidar Ayoub, Georgi V. Todorov, Fedya P. Nikolov, Elena S. Velcheva, Maria L. Tzekova, Haralambi O. Benov, Stanislav L. Petranov, Haralin S. Tumbev, Nina S. Shehova-Yankova, Dimitar T. Markov, Dimitar H. Raev, Mihail N. Mollov, Kostadin N. Kichukov, Katya A. Ilieva-Pandeva, Raya Ivanova, Maryana Gospodinov, Valentina M. Mincheva, Petar V. Lazov, Bojidar I. 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Raffo, Claudia Olivares, Leonardo Nahuelpan, Humberto Montecinos, Jiyan Chen, Yugang Dong, Weijian Huang, Jianzhong Wang, Shi'An Huang, Zhuhua Yao, Xiang Li, Lan Cui, Wenhua Lin, Yuemin Sun, Jingfeng Wang, Jianping Li, Xuelian Zhang, Hong Zhu, Dandan Chen, Lan Huang, Shaohong Dong, Guohai Su, Biao Xu, Xi Su, Xiaoshu Cheng, Jinxiu Lin, Wenxia Zong, Huanming Li, Yi Feng, Dingli Xu, Xinchun Yang, Yuannan Ke, Xuefeng Lin, Zheng Zhang, Zeqi Zheng, Zhurong Luo, Yundai Chen, Chunhua Ding, Yi Zhong, Yang Zheng, Xiaodong Li, Daoquan Peng, Shuiping Zhao, Ying Li, Xuebo Liu, Meng Wei, Shaowen Liu, Yihua Yu, Baiming Qu, Weihong Jiang, Yujie Zhou, Xingsheng Zhao, Zuyi Yuan, Ying Guo, Xiping Xu, Xubo Shi, Junbo Ge, Guosheng Fu, Feng Bai, Weiyi Fang, Xiling Shou, Xiangjun Yang, Jian'An Wang, Meixiang Xiang, Yingxian Sun, Qinghua Lu, Ruiyan Zhang, Jianhua Zhu, Yizhou Xu, Zhongcai Fan, Tianchang Li, Chun Wu, Nicolas Jaramillo, Gregorio Sanchez Vallejo, Diana C. 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Fernandez Trujillo, Maja Strozzi, Siniša Car, Melita Jerić, Davor Miličić, Martina Lovrić Benčić, Hrvoje Pintarić, Đeiti Prvulović, Jozica Šikić, Viktor Peršić, Dean Mileta, Kresimir Štambuk, Zdravko Babić, Vjekoslav Tomulic, Josip Lukenda, Stanka Mejic-Krstulovic, Boris Starcevic, Jindrich Spinar, David Horak, Zdenek Velicka, Josef Stasek, David Alan, Vilma Machova, Ales Linhart, Vojtech Novotny, Vladimir Kaucak, Richard Rokyta, Robert Naplava, Zdenek Coufal, Vera Adamkova, Ivo Podpera, Jiri Zizka, Zuzana Motovska, Ivana Marusincova, Premysl Svab, Petr Heinc, Jiri Kuchar, Petr Povolny, Jiri Matuska, Steen H. Poulsen, Bent Raungaard, Peter Clemmensen, Lia E. Bang, Ole May, Morten Bøttcher, Jens D. Hove, Lars Frost, Gunnar Gislason, John Larsen, Peter Betton Johansen, Flemming Hald, Peter Johansen, Jørgen Jeppesen, Tonny Nielsen, Kjeld S. Kristensen, Piotr Maria Walichiewicz, Jens D. Lomholdt, Ib C. 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Fausto Ovando, Juan L. Arango Benecke, Edgar R. Rodriguez De Leon, Bryan P.Y. Yan, David C.W. Siu, Tibor Turi, Bela Merkely, Imre Ungi, Geza Lupkovics, Lajos Nagy, András Katona, István Édes, Gábor Müller, Iván Horvath, Tibor Kapin, Zsolt Szigeti, József Faluközy, Mukund Kumbla, Manjinder Sandhu, Sharath Annam, Naveen Reddy Proddutur, Reddy Regella, Rajendra K. Premchand, Ajaykumar Mahajan, Sudhir Pawar, Atul D. Abhyanakar, Prafulla Kerkar, Ravishankar A. Govinda, Abraham Oomman, Dhurjati Sinha, Sachin N. Patil, Dhiman Kahali, Jitendra Sawhney, Abhijeet B. Joshi, Sanjeev Chaudhary, Pankaj Harkut, Santanu Guha, Sanjay Porwal, Srimannarayana Jujjuru, Ramesh B. Pothineni, Minguel R. Monteiro, Aziz Khan, Shamanna S. Iyengar, Jasprakash Singh Grewal, Manoj Chopda, Mahesh C. Fulwani, Aparna Patange, Patil Sachin, Vijay K. Chopra, Naresh K. Goyal, Rituparna Shinde, Gajendra V. 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De Cesare, Sergio Berti, Claudio Cavallini, Enrico Puccioni, Marcello Galvani, Maurizio Tespili, Piermarco Piatti, Michela Palvarini, Giuseppe De Luca, Roberto Violini, Alessandro De Leo, Zoran Olivari, Pasquale Perrone Filardi, Maurizio Ferratini, Vittorio Racca, Kazuoki Dai, Yuji Shimatani, Haruo Kamiya, Kenji Ando, Yoshihiro Takeda, Yoshihiro Morino, Yoshiki Hata, Kazuo Kimura, Koichi Kishi, Ichiro Michishita, Hiroki Uehara, Toshinori Higashikata, Atsushi Hirayama, Keiji Hirooka, Yasuji Doi, Satoru Sakagami, Shuichi Taguchi, Akihiro Koike, Hiroyuki Fujinaga, Shinji Koba, Ken Kozuma, Tomohiro Kawasaki, Yujiro Ono, Masatoshi Shimizu, Yousuke Katsuda, Atsuyuki Wada, Toshiro Shinke, Junya Ako, Kenshi Fujii, Toshiyuki Takahashi, Tomohiro Sakamoto, Koichi Nakao, Yutaka Furukawa, Hiroshi Sugino, Ritsu Tamura, Toshiaki Mano, Masaaki Uematsu, Noriaki Utsu, Kashima Ito, Takuya Haraguchi, Katsuhiko Sato, Yasunori Ueda, Akira Nishibe, Kazuteru Fujimoto, Motomaru Masutani, Jung Han Yoon, Hack-Lyoung Kim, Hun Sik Park, In-Ho Chae, Moo Hyun Kim, Myung Ho Jeong, Seungwoon Rha, Chongjin Kim, Hae Young Kim, Taekjong Hong, Seung-Jea Tahk, Youngkwon Kim, Arija Busmane, Natalija Pontaga, Aldis Strelnieks, Iveta Mintale, Iveta Sime, Zaneta Petrulioniene, Roma Kavaliauskiene, Ruta Jurgaitiene, Gintare Sakalyte, Rimvydas Slapikas, Sigute Norkiene, Nerijus Misonis, Aleksandras Kibarskis, Raimondas Kubilius, Stojko Bojovski, Nensi Lozance, Aleksandar Kjovkaroski, Snezana Doncovska, Tiong Kiam Ong, Sazzli Kasim, Oteh Maskon, Balachandran Kandasamy, Houng B. Liew, Wan Mohd Izani Wan Mohamed, Armando García Castillo, Jorge Carrillo Calvillo, Pedro Fajardo Campos, Juan Carlos Núñez Fragoso, Edmundo Alfredo Bayram Llamas, Marco Antonio Alcocer Gamba, Jaime Carranza Madrigal, Luis Gerardo González Salas, Enrique López Rosas, Belinda González Díaz, Eduardo Salcido Vázquez, Alfredo Nacoud Ackar, Guillermo Antonio Llamas Esperón, Carlos Rodolfo Martínez Sánchez, María Guerrero De Leon, Rodrigo Suarez Otero, Guillermo Fanghänel Salmón, Jesús Antonio Pérez Ríos, José Angel Garza Ruíz, Robert W. Breedveld, Margriet Feenema-Aardema, Alida Borger-Van Der Burg, Pieter A.M. Hoogslag, Harry Suryapranata, Antonius Oomen, Paulus Van Haelst, Margriet Feenema-Aradema, Jacobijne J. Wiersma, Dirk Basart, Ruud M.A. Van Der Wal, Peter Zwart, Pascalle Monraats, Henricus Van Kesteren, Ioannis Karalis, Johan Jukema, Gerardus J.E. Verdel, Bart R.G. Brueren, Roland PTh Troquay, Eric P. Viergever, Nadea Y.Y. Al-Windy, Gerard L. Bartels, Jan H. Cornel, Walter R.M. Hermans, Johannes P.R. Herrman, Robert J. Bos, Reginald G.E.J. Groutars, Coenraad C. Van Der Zwaan, Refik Kaplan, Raymond Lionarons, Eelko Ronner, Bjorn E. Groenemeijer, Patrick N.A. Bronzwaer, Anho A.H. Liem, Bernard J.W.M. Rensing, Marcel J.J.A. Bokern, Remco Nijmeijer, Ferry M.R.J. Hersbach, Frank F. Willems, Antonius T.M. Gosselink, Saman Rasoul, John Elliott, Gerard Wilkins, Raewyn Fisher, Douglas Scott, Hamish Hart, Ralph Stewart, Scott Harding, Ian Ternouth, Nicholas Fisher, Samuel Wilson, Denise Aitken, Russell Anscombe, Laura Davidson, Tadeusz Tomala, Ottar Nygård, Jon Arne Sparby, Kjell Andersen, Lars Gullestad, Jarle Jortveit, Peter S. Munk, Erlend gyllensten Singsaas, Ulf Hurtig, Jorge R. Calderon Ticona, Julio R. Durand Velasquez, Sandra A. Negron Miguel, Enrique S. Sanabria Perez, Jesus M. Carrion Chambilla, Carlos A. Chavez Ayala, Reynaldo P. Castillo Leon, Rolando J. Vargas Gonzales, Jose D. Hernandez Zuniga, Luis A. Camacho Cosavalente, Jorge E. Bravo Mannucci, Javier Heredia Landeo, Nassip C. Llerena Navarro, Yudy M. Roldan Concha, Víctor E. Rodriguez Chavez, Henry A. Anchante Hernandez, Carlos A. Zea Nunez, Walter Mogrovejo Ramos, Arthur Ferrolino, Rosa Allyn G. Sy, Louie Tirador, Generoso Matiga, Raul Martin Coching, Alisa Bernan, Gregorio Rogelio, Dante D. Morales, Edgar Tan, Dennis Jose Sulit, Adrian Wlodarczak, Krystyna Jaworska, Grzegorz Skonieczny, Lidia Pawlowicz, Pawel Wojewoda, Benita Busz-Papiez, Janusz Bednarski, Aleksander Goch, Pawel Staneta, Elzbieta Dulak, Krzysztof Saminski, Wlodzimierz Krasowski, Wanda Sudnik, Aleksander Zurakowski, Marcin Skorski, Roman Lysek, Beata Miklaszewicz, Jacek Kubica, Jan Andrzej Lipko, Edyta Kostarska-Srokosz, Marek Piepiorka, Anna Drzewiecka, Ryszard Sciborski, Arkadiusz Stasiewski, Tomasz Blicharski, Leszek Bystryk, Michal Szpajer, Marek Korol, Tomasz Czerski, Ewa Mirek-Bryniarska, Jacek Gniot, Andrzej Lubinski, Jerzy Gorny, Edward Franek, Grzegorz Raczak, Hanna Szwed, Pedro Monteiro, Jose Mesquita Bastos, Helder H. Pereira, Dinis Martins, Filipe Seixo, Carlos Mendonça, Ana Botelho, Francisca Caetano, Bogdan Minescu, Octavian Istratoaie, Dan N. Tesloianu, Gabriel Cristian, Silviu Dumitrescu, Cristian G.C. Podoleanu, Mircea C.A. Constantinescu, Cristina M. Bengus, Constantin Militaru, Doina Rosu, Irinel R. Parepa, Adrian V. Matei, Tom M. Alexandru, Mihaela Malis, Ioan Coman, Rodica Stanescu-Cioranu, Doina Dimulescu, Yury Shvarts, Olga Orlikova, Zhanna Kobalava, Olga L. Barbarash, Valentin Markov, Nadezhda Lyamina, Alexander Gordienko, Konstantin Zrazhevsky, Alexander Y. Vishnevsky, Victor Gurevich, Raisa Stryuk, Nikita V. Lomakin, Igor Bokarev, Tatiana Khlevchuk, Sergey Shalaev, Larisa Khaisheva, Petr Chizhov, Inna Viktorova, Natalya Osokina, Vladimir Shchekotov, Evgenia Akatova, Galina Chumakova, Igor Libov, Mikhail I. Voevoda, Tatyana V. Tretyakova, Evgeny Baranov, Sergey Shustov, Sergey Yakushin, Ivan Gordeev, Niiaz Khasanov, Olga Reshetko, Tatiana Sotnikova, Olga Molchanova, Konstantin Nikolaev, Liudmila Gapon, Elena Baranova, Zaur Shogenov, Elena Kosmachova, Yuriy Karpov, Anton Povzun, Liudmila Egorova, Vadim V. Tyrenko, Igor G. Ivanov, Masterov Ilya, Sergey Kanorsky, Dragan Simic, Nikola Ivanovic, Goran Davidovic, Nebojsa Tasic, Milika R. Asanin, Stevo Stojic, Svetlana R. Apostolovic, Stevan Ilic, Biljana Putnikovic Tosic, Aleksandar Stankovic, Aleksandra Arandjelovic, Slavica Radovanovic, Branislava Todic, Jovan Balinovac, Dragan V. Dincic, Petar Seferovic, Ana Karadzic, Slobodan Dodic, Sinisa Dimkovic, Tamara Jakimov, Kian-Keong Poh, Hean Yee Ong, Justin Tang I-Shing, Karol Micko, Jan Nociar, Daniel Pella, Peter Fulop, Marian Hranai, Juraj Palka, Juraj Mazur, Ivan Majercák, Andrej Dzupina, František Fazekas, Jozef Gonsorcik, Viliam Bugan, Juraj Selecky, Gabriel Kamensky, Jaroslava Strbova, Rudolf Smik, Andrej Dukat, Peter Olexa, Ivan Žuran, Janez Poklukar, Nataša Černič Šuligoj, Matija Cevc, Henry P. Cyster, Naresh Ranjith, Clive Corbett, Junaid Bayat, Ellen Makoali Makotoko, Hendrik du Toit Theron, Ilse E. Kapp, Matthys M. de V Basson, Hanlie Lottering, Dina Van Aswegen, Louis J. Van Zyl, Peter J. Sebastian, Thayabran Pillay, Jan A. Saaiman, Patrick J. Commerford, Soraya Cassimjee, Garda Riaz, Iftikhar O. Ebrahim, Mahomed Sarvan, Joseph H. Mynhardt, Helmuth Reuter, Rajendran Moodley, Manuel Vida, Angel R. Cequier Fillat, Vicente Bodí Peris, Francisco Fuentes Jimenez, Francisco Marín, Jose M. Cruz Fernández, Rafael Jesus Hidalgo Urbano, Blas Gil-Extremera, Pablo Toledo, Fernando Worner Diz, David Garcia-Dorado, Andres Iñiguez, José Tuñón Fernández, Jose R. Gonzalez-Juanatey, Javier Fernandez Portales, Fernando Civeira Murillo, Laia Matas Pericas, Jose Luis Zamorano, Manuel De Mora Martin, Jordi Bruguera Cortada, Joaquin J. Alonso Martin, Jose Maria Serrano Antolin, José R. De Berrazueta Fernández, José Antonio Vázquez de Prada, Jose Francisco Díaz Fernández, José Alberto García Lledó, Juan Cosín Sales, Javier Botas Rodriguez, Gabriel Gusi Tragant, Amparo Benedicto, Carlos Gonzalez-Juanatey, Mercedes Camprubí Potau, Ignacio Plaza Perez, César Morís De La Tassa, Pablo Loma-Osorio Rincon, Javier Balaguer Recena, Juan M. Escudier, Antonio Coca Payeras, Norberto Alonso Orcajo, Pedro Valdivielso, Godwin Constantine, Ruvaiz Haniffa, Nirmali Tissera, Stanley Amarasekera, Chandrike Ponnamperuma, Nimali Fernando, Kaputella Fernando, Jayanthimala Jayawardena, Santharaj Wijeyasingam, Gotabhaya Ranasinghe, Ruvan Ekanayaka, Sepalika Mendis, Vajira Senaratne, Gnanamoorthy Mayurathan, Ajantha Rajapaksha, Thilak Sirisena, Jagath I. Herath, Naomali Amarasena, Stefan Berglund, Gundars Rasmanis, Ola Vedin, Nils Witt, Georgios Mourtzinis, Peter Nicol, Ole Hansen, Stefano Romeo, Steen Agergaard Jensen, Ingemar Torstensson, Ulf Ahremark, Torbjörn Sundelin, Tiziano Moccetti, Francois Mach, Ronald Binde, Oliver Gämperli, Wei-Chuan Tsai, Kwo-Chang Ueng, Wen-Ter Lai, Ming-En Liu, Juey-Jen Hwang, Wei-Hsian Yin, I-Chang Hsieh, Ming-Jer Hsieh, Wei Hsiang Lin, Jen-Yuan Kuo, Tsuei-Yuan Huang, Chih-Yuan Fang, Pinij Kaewsuwanna, Wasant Soonfuang, Woravut Jintapakorn, Apichard Sukonthasarn, Nattawut Wongpraparut, Krisada Sastravaha, Nakarin Sansanayudh, Wirash Kehasukcharoen, Dilok Piyayotai, Paiboon Chotnoparatpat, Ahmet Camsari, Hakan Kultursay, Bulent Mutlu, Murat Ersanli, Mustafa Demirtas, Cevat Kirma, Ertan Ural, Lale Koldas, Oleksandr Karpenko, Alexander Prokhorov, Ihor Vakaluyk, Halyna Myshanych, Dmytro Reshotko, Valeriy Batushkin, Leonid Rudenko, Ihor Kovalskyi, Mykola Kushnir, Vira Tseluyko, Yuriy Mostovoy, Mykola Stanislavchuk, Yulian Kyiak, Yuriy Karpenko, Yaroslav Malynovsky, Andriy Klantsa, Oles Kutniy, Ekaterina Amosova, Viktor Tashchuk, Oleh Leshchuk, Mykola Rishko, Mykola Kopytsya, Andriy Yagensky, Mykola Vatutin, Andriy Bagriy, Olga M. Barna, Olexiy Ushakov, Georgiy Dzyak, Borys Goloborodko, Anatolii Rudenko, Volodymyr Zheleznyy, Jasper Trevelyan, Azfar Zaman, Kaeng Lee, Andrew Moriarty, Rajesh K. Aggarwal, Piers Clifford, Yuk-Ki Wong, Syed M.R. Iqbal, Eduardas Subkovas, Denise Braganza, David Sarkar, Robert Storey, Huw Griffiths, Sam Mcclure, Rangasamy Muthusamy, Simon Smith, John Kurian, Terry Levy, Craig Barr, Honer Kadr, Robert Gerber, Audrius Simaitis, Handrean Soran, Anthony Mathur, Adrian Brodison, Mohammad Ayaz, Muhammad Cheema, Richard Oliver, Simon Thackray, Telal Mudawi, Gohar Rahman, Ayyaz Sultan, Timothy Reynolds, David Sharman, null david Sprigings, Rob Butler, Peter Wilkinson, Gregory Y.H. Lip, Julian Halcox, Sean Gallagher, Nicholas Ossei-Gerning, Gil Vardi, Duccio Baldari, David Brabham, Charles Treasure, Charles Dahl, Bruce Palmer, Alan Wiseman, Abul Khan, Sanjeev Puri, Ann Elizabeth Mohart, Carlos Ince, Enrique Flores, Scott Wright, Shi-Chi Cheng, Michael Rosenberg, William Rogers, Edward Kosinski, Les Forgosh, Jonathan Waltman, Misal Khan, Mohammad Shoukfeh, Georges Dagher, Patrick Cambier, Ira Lieber, Priya Kumar, Cara East, Perry Krichmar, Mian Hasan, Lindsey White, Thomas Knickelbine, Thomas Haldis, Eve Gillespie, Thomas Amidon, David Suh, Imran Arif, Mouhamad Abdallah, Faiq Akhter, Eric Carlson, Michael D'Urso, Fadi El-Ahdab, William Nelson, Katie Moriarty, Barry Harris, Steven Cohen, Luther Carter, Daniel Doty, Kenneth Sabatino, Tariq Haddad, Amir Malik, Sunder Rao, Angel Mulkay, Ion Jovin, Kim Klancke, Vinay Malhotra, Sai K. Devarapalli, Michael Koren, Harish Chandna, George Dodds, Tauqir Goraya, James Bengston, Matthew Janik, Joseph Moran, Andrew Sumner, John Kobayashi, William Davis, Shahram Yazdani, John Pasquini, Maitreya Thakkar, Amarnath Vedere, Wayne Leimbach, James Rider, Sarah fenton, Narendra Singh, Anil V. Shah, Denise Janosik, Carl Pepine, Brett Berman, Joseph Gelormini, Christopher Daniels, Kerensky Richard, Friederike Keating, Nicholas I. Kondo, Sanjay Shetty, Howard Levite, Winfried Waider, Theodore Takata, Mazen Abu-Fadel, Vipul Shah, Rahul Aggarwal, Mark Izzo, Anil Kumar, Brack Hattler, Rose Do, Chad Link, Anna Bortnick, George Kinzfogl, Arnold Ghitis, John Larry, Edward Teufel, Peter Kuhlman, Brent Mclaurin, Wenwu Zhang, Stephen Thew, Jalal Abbas, Matthew White, Othman Islam, Sumeet Subherwal, Nandkishore Ranadive, Babak Vakili, Christian Gring, David Henderson, Timothy Schuchard, Naim Farhat, Geoffrey Kline, Sharan Mahal, Jack Whitaker, Shawn Speirs, Rolf Andersen, Nizar Daboul, Phillip Horwitz, Firas Zahr, George Ponce, Zubair Jafar, Joseph Mcgarvey, Vipul Panchal, Stephen Voyce, Thomas Blok, William Sheldon, Masoud M. Azizad, Carsten Schmalfuss, Mark Picone, Robert Pederson, William Herzog, Keith Friedman, Jason Lindsey, Rosemary Nowins, Eichenlaub Timothy, Parilak Leonard, Norman Lepor, Mahfouz El Shahawy, Howard Weintraub, Anand Irimpen, Alvaro Alonso, Wade May, Daniels Christopher, Thomas Galski, Alan Chu, Freny Mody, Ebrahimi Ramin, Zachary Hodes, Joseph Rossi, Gregory Rose, James Fairlamb, Charles Lambert, Ajit Raisinghani, Antonio Abbate, George Vetrovec, Marilyn King, Charles Carey, Jaime Gerber, Liwa Younis, Hyeun Park, Mladen Vidovich, Thomas Knutson, Dennis Friedman, Fred Chaleff, Arthur Loussararian, Phillip Rozeman, Carey Kimmelstiel, Jeffrey Kuvin, Kevin Silver, Malcolm Foster, Glen Tonnessen, Andrey Espinoza, Mohamadali Amlani, Andreas Wali, Christopher Malozzi, Geert T. Jong, Clara Massey, Keattiyoat Wattanakit, Philip J. O'Donnell, Dinesh Singal, Naseem Jaffrani, Sridhar Banuru, Daniel Fisher, Mark Xenakis, Neal Perlmutter, Ravi Bhagwat, James Strader, Ronald Blonder, Ayim Akyea-Djamson, Ajay Labroo, Kwan Lee, H. John Marais, Edmund Claxton, Robert Weiss, Rohr Kathryn, Martin Berk, Peter Rossi, Parag Joshi, Amit Khera, Ajit S. Khaira, Greg Kumkumian, Steven Lupovitch, Joshua Purow, Stephen Welka, David Hoffman, Stuart Fischer, Eugene Soroka, Donald Eagerton, Samir Pancholy, Michael Ray, Norman Erenrich, Michael Farrar, Stewart Pollock, William J. French, Steve Diamantis, Douglas Guy, Lawrence Gimple, Mark Neustel, Steven Schwartz, Edward Pereira, Seals Albert, Douglas Spriggs, Janet Strain, Suneet Mittal, Anthony Vo, Majed Chane, Jason Hall, Nampalli Vijay, Kapildeo Lotun, F. Martin Lester, Ahed Nahhas, Theodore Pope, Paul Nager, Rakesh Vohra, Mukesh Sharma, Riyaz Bashir, Hinan Ahmed, Michael Berlowitz, Robert Fishberg, Robert Barrucco, Eric Yang, Michael Radin, Daniel Sporn, Dwight Stapleton, Steven Eisenberg, Joel Landzberg, Martin Mcgough, Samir Turk, Michael Schwartz, P. Sandy Sundram, Diwakar Jain, Mark Zainea, Carlos Bayron, Ronald Karlsberg, Suhail Dohad, Henry Lui, William Keen, Donald Westerhausen, Sandeep Khurana, Himanshu Agarwal, Jessica Birchem, William Penny, Mark Chang, Sherrill Murphy, John Henry, Branislav Schifferdecker, John M Gilbert, Gopal Chalavarya, Charles Eaton, John F. Schmedtje, Stuart Christenson, Imran Dotani, Douglas Denham, Alexander Macdonell, Paul Gibson, Aref Rahman, Tammam Al Joundi, Nizar Assi, Gary Conrad, Purushotham Kotha, Michael Love, Gregory Giesler, Howard Rubenstein, Dawood Gamil, Laura Akright, Justine Krawczyk, Joanne Cobler, Terry Wells, James Welker, Robert Foster, Richard Gilmore, Jay Anderson, Douglas Jacoby, Bill Harris, Geraldine Gardner, Ramprasad Dandillaya, Kishor Vora, John Kostis, John Hunter, David Laxson, Eric Ball, Flavia Egydio, Anelise Kawakami, Janaina Oliveira, Julianna Wozniak, Alexander Matthews, Caroline Ratky, Janine Valiris, Lisa Berdan, Anita Hepditch, Kirby Quintero, Tyrus Rorick, Melissa Westbrook, Andrea Pascual, Carla Rovito, Madeleine Bezault, Elodie Drouet, Tabassome Simon, Caroline Alsweiler, Anne Luyten, Julie Butters, Liddy Griffith, Michelle Shaw, Lena Grunberg, Shahidul Islam, Marie-France Brégeault, Nathalie Bougon, Douglas Faustino, Sylvie Fontecave, Judith Murphy, Melanie Verrier, null Veronique Agnetti, Dorthe Andersen, Emmy Badreddine, Mhamed Bekkouche, Cecile Bouancheau, Imane Brigui, Maddy Brocklehurst, Joseph Cianciarulo, Dawn Devaul, Szilvia Domokos, Cecile Gache, Caroline Gobillot, Severine Guillou, Jan Healy, Megan Heath, Gayatri Jaiwal, Carine Javierre, Julien Labeirie, Myriam Monier, Ulises Morales, Asmaa Mrabti, Bicky Mthombeni, Betim Okan, Lucile Smith, Jennifer Sheller, Sebastien Sopena, Valerie Pellan, Fadela Benbernou, Nafissa Bengrait, Maud Lamoureux, Katarina Kralova, Raphael Bejuit, Anthony Coulange, Christelle Berthou, Jérôme Repincay, Christelle Lorenzato, Alexis Etienne, Valerie Gouet, Virginie Loizeau, Mickael Normand, Anne Ourliac, Christelle Rondel, Antony Adamo, Pascale Beltran, Pauline Barraud, Helene Dubois-Gache, Benjamin Halle, Lamia Metwally, Maxime Mourgues, Marc Sotty, Marion Vincendet, Raluca Cotruta, Zhu Chengyue, Dominique Fournie-Lloret, Christine Morrello, Aurelie Perthuis, Patrick Picault, Isabelle Zobouyan, Helen M. Colhoun, Michael A. Dempsey, Mark A. McClanahan, Masira, and Laucevičius, Aleksandras
Subjects: Male, Acute coronary syndrome, medicine.medical_specialty, Cardiac & Cardiovascular Systems, Randomization, PCSK9 inhibitor, LOW-DENSITY-LIPOPROTEIN, Antibodies, Monoclonal, Humanized, acute coronary syndrom, Placebo, Gastroenterology, lipoprotein(a), Internal medicine, medicine, Humans, Low-density lipoprotein cholesterol, Aged, Alirocumab, RISK, low-density lipoprotein cholesterol, Science & Technology, biology, business.industry, PCSK9, PCSK9 Inhibitors, Hazard ratio, ALIROCUMAB, acute coronary syndrome, Cholesterol, LDL, Lipoprotein(a), Middle Aged, EFFICACY, medicine.disease, Cardiovascular Diseases, CARDIOVASCULAR-DISEASE, SAFETY, Cardiovascular System & Cardiology, biology.protein, Female, lipids (amino acids, peptides, and proteins), STATIN, low-density lipoprotein, cholesterol PCSK9 inhibitor, CORONARY, Cardiology and Cardiovascular Medicine, business, Life Sciences & Biomedicine, Mace
Abstract: Digital, Background Guidelines recommend nonstatin lipid-lowering agents in patients at very high risk for major adverse cardiovascular events (MACE) if low-density lipoprotein cholesterol (LDL-C) remains ≥70 mg/dL on maximum tolerated statin treatment. It is uncertain if this approach benefits patients with LDL-C near 70 mg/dL. Lipoprotein(a) levels may influence residual risk. Objectives In a post hoc analysis of the ODYSSEY Outcomes (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) trial, the authors evaluated the benefit of adding the proprotein subtilisin/kexin type 9 inhibitor alirocumab to optimized statin treatment in patients with LDL-C levels near 70 mg/dL. Effects were evaluated according to concurrent lipoprotein(a) levels. Methods ODYSSEY Outcomes compared alirocumab with placebo in 18,924 patients with recent acute coronary syndromes receiving optimized statin treatment. In 4,351 patients (23.0%), screening or randomization LDL-C was 13.7 mg/dL or ≤13.7 mg/dL; corresponding adjusted treatment hazard ratios were 0.82 (95% CI: 0.72-0.92) and 0.89 (95% CI: 0.75-1.06), with Pinteraction = 0.43. Conclusions In patients with recent acute coronary syndromes and LDL-C near 70 mg/dL on optimized statin therapy, proprotein subtilisin/kexin type 9 inhibition provides incremental clinical benefit only when lipoprotein(a) concentration is at least mildly elevated. (ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab; NCT01663402), Ciencias Médicas y de la Salud
Published: 2021
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22. A adubação nitrogenada e o sintoma de nematóides no algodoeiro

Author: N. M. Silva, M. G. Fuzatto, J. I. Kondo, J. C. Sabino, A. Pettinelli Jr., and P. B. Gallo
Subjects: algodão, N-foliar e produtividade, sintomas de "carijó" e cobertura nitrogenada, Agriculture (General), S1-972
Abstract: Em dois ensaios de campo de adubação nitrogenada, desenvolvidos com o cultivar IAC 20 de algodão em solos infestados por nematóides, nos municípios de Mococa e Tatuí (SP), em 1988/89, observou-se que a incidência de sintomas na parte aérea das plantas ocorreu de forma diferenciada em função dos tratamentos (0, 25, 50 e 75 kg ha-1 de N-cobertura). Efetuou-se, então, levantamento de sintomas, por parcela experimental, atribuindo às plantas notas crescentes de acordo com a intensidade do ataque: nota 1, para plantas com porte normal e isentas de manchas amareladas e/ou avermelhadas, salpicadas no limbo foliar ("carijó"); 2, com "carijó" (sintoma típico de mosqueamento foliar) nas folhas da base da copa ("baixeiro"); 3, com "carijó" no "baixeiro" e em folhas esparsas; 4, com "carijó" incluindo folhas do ponteiro, e nota 5, para plantas com "carijó" generalizado e deficiente desenvolvimento. A capacidade produtiva do algodoeiro, avaliada nas parcelas sem N, caiu, gradativamente, com a intensidade do "carijó", em especial após nota 3,0, que, em média, representa o deslocamento do sintoma para o ponteiro das plantas. A adubação nitrogenada, por contribuir, significativamente, para diminuir o "carijó" e para aumentar a concentração de N-foliar e a produtividade, pode representar uma alternativa viável no complemento da resistência varietal.
Published: 1997
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23. On The Uniqueness of Solutions for Kawahara Type Equations

Author: Marcos A. de Farias, José Ruidival dos Santos Filho, and Cezar I. Kondo
Subjects: Physics, General Mathematics, Mathematics::Analysis of PDEs, Applied mathematics, Uniqueness, Type (model theory)
Abstract: In this paper we extend to Kawahara type equations a uniqueness result obtained by C. E. Kenig, G. Ponce, and L. Vega for KdV type equations. We prove that, under certain decay's conditions, the null solution is the unique solution.
Published: 2018
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24. A massive tsunami promoted gene flow and increased genetic diversity in a near threatened plant species

Author: Hidenobu Kunii, Natsuko I. Kondo, Masakazu Shimada, Kako Ohbayashi, and Yoshikuni Hodoki
Subjects: 0106 biological sciences, 0301 basic medicine, Gene Flow, lcsh:Medicine, 010603 evolutionary biology, 01 natural sciences, Article, 03 medical and health sciences, Japan, Genetic variation, lcsh:Science, Carex, geography, Genetic diversity, Multidisciplinary, geography.geographical_feature_category, Near-threatened species, Pacific Ocean, biology, Ecology, lcsh:R, Species diversity, Genetic Variation, biology.organism_classification, 030104 developmental biology, Habitat, Disturbance (ecology), Tsunamis, Salt marsh, lcsh:Q, Carex Plant, human activities
Abstract: The magnitude and frequency of disturbances affect species diversity and spatial distributions, but the direct effects of large-scale disturbances on genetic diversity are poorly understood. On March 11, 2011, the Great Tohoku Earthquake in Japan caused a massive tsunami that resulted in substantial alteration of community compositions. Populations of a near-threatened tidal marsh Carex rugulosa inhabiting brackish sandbars was also affected. We found four out of six remnant C. rugulosa populations along the Pacific Ocean had become completely extinct. Newly emergent post-tsunami populations, however, had higher allelic numbers than pre-tsunami populations, indicating higher genetic diversity after the tsunami. In addition, genetic differentiation (Fst) between post-tsunami populations was significantly lower than that of pre-tsunami populations. We therefore conclude that the tsunami enhanced gene flow. Seeds of many Carex species persist for long periods in soil, which suggests that seed banks are important genetic resources for post-disturbance recovery of genetic diversity. When its brackish sandbar habitat is no longer subject to disturbance and changes to the land, C. rugulosa is outcompeted by terrestrial plant competitors and eliminated. Disturbance is a driving force for the recovery and maintenance of populations of species such as C. rugulosa—even after near-complete eradication.
Published: 2017
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25. Melanic mutation causes a fitness decline in bean beetles infected byWolbachia

Author: Natsuko I. Kondo, Yukihiko Toquenaga, and Yuko Numajiri
Subjects: 0301 basic medicine, media_common.quotation_subject, ved/biology.organism_classification_rank.species, Population, Zoology, Parasitism, Biology, 03 medical and health sciences, parasitic diseases, Botany, education, reproductive and urinary physiology, Ecology, Evolution, Behavior and Systematics, Callosobruchus chinensis, media_common, education.field_of_study, Host (biology), ved/biology, Melanism, Longevity, biochemical phenomena, metabolism, and nutrition, Fecundity, biology.organism_classification, 030104 developmental biology, Insect Science, bacteria, Wolbachia
Abstract: Wolbachia cannot live outside a host, which is thought to be the reason for host-Wolbachia coevolution toward benign parasitism, especially because the fitness of Wolbachia is traded against its host's fitness. Insect melanism has been reported to have a positive effect on pathogen resistance, but melanic mutants of Callosobruchus analis (Fabricius) and Callosobruchus chinensis (L.) (Coleoptera: Chrysomelidae) are infected with Wolbachia. Callosobruchus chinensis is infected with CI-inducing Wolbachia, and melanic mutants exhibit fitness decline. Interestingly, this decline is not observed in C. analis melanic mutants that are infected with CI-free Wolbachia. Our research question is whether the infection of CI-inducing Wolbachia causes fitness decline of melanic hosts in C. analis. We examined fecundity, fertility, and longevity of C. analis melanic mutants and compared them between uninfected and infected hosts with CI-inducing Wolbachia. Infected melanic mutants of C. analis exhibited fitness decline leading to reduced hatch rates even when parental combinations were compatible. Wolbachia can invade a host population by causing CI to decrease the fraction of uninfected hosts, but melanic mutant hosts decrease the number of infected hosts through fitness decline. Nevertheless, the melanism in hosts is not able to stop Wolbachia invasion in C. analis.
Published: 2017
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26. Periodic traveling wave solution for non-homogeneous BBM and KdVB equations

Author: Cezar I. Kondo, José Ruidival dos Santos Filho, and Marcos A. de Farias
Subjects: Applied Mathematics, Mathematical analysis, General Engineering, General Medicine, Fixed point, Space (mathematics), Compact operator, Integral equation, Periodic function, Computational Mathematics, Non homogeneous, Traveling wave, Boundary value problem, General Economics, Econometrics and Finance, Analysis, Mathematics
Abstract: In this paper the Green’s function method and results about fixed point are used to get existence results on periodic traveling wave solution for non-homogeneous problems of generalized versions of the BBM and KdVB equations. It is shown through the constructions of explicit Green’s functions that the periodic boundary value problems for the traveling wave solutions of the BBM and KdVB equations are equivalent to integral equations which generate compact operators in the space of periodic functions. These integral representations allowed us to prove that if the speed of the wave propagation is suitably chosen, then the BBM and KdVB equations will admit periodic traveling wave solution.
Published: 2017
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27. Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial

Author: Kausik K Ray, Helen M Colhoun, Michael Szarek, Marie Baccara-Dinet, Deepak L Bhatt, Vera A Bittner, Andrzej J Budaj, Rafael Diaz, Shaun G Goodman, Corinne Hanotin, Robert A Harrington, J Wouter Jukema, Virginie Loizeau, Renato D Lopes, Angèle Moryusef, Jan Murin, Robert Pordy, Arsen D Ristic, Matthew T Roe, José Tuñón, Harvey D White, Andreas M Zeiher, Gregory G Schwartz, Philippe Gabriel Steg, Gregory G. Schwartz, Ph. Gabriel Steg, Deepak L. Bhatt, Vera A. Bittner, Shaun G. Goodman, Robert A. Harrington, J. Wouter Jukema, Harvey D. White, Andreas M. Zeiher, Pierluigi Tricoci, Matthew T. Roe, Kenneth W. Mahaffey, Jay M. Edelberg, Guillaume Lecorps, William J. Sasiela, Jean-François Tamby, Philip E. Aylward, Heinz Drexel, Peter Sinnaeve, Mirza Dilic, Renato D. Lopes, Nina N. Gotcheva, Juan-Carlos Prieto, Huo Yong, Patricio López-Jaramillo, Ivan Pećin, Zeljko Reiner, Petr Ostadal, Margus Viigimaa, Markku S. Nieminen, Vakhtang Chumburidze, Nikolaus Marx, Nicolas Danchin, Evangelos Liberopoulos, Pablo Carlos Montenegro Valdovinos, Hung-Fat Tse, Robert Gabor Kiss, Denis Xavier, Doron Zahger, Marco Valgimigli, Takeshi Kimura, Hyo Soo Kim, Sang-Hyun Kim, Andrejs Erglis, Aleksandras Laucevicius, Sasko Kedev, Khalid Yusoff, Gabriel Arturo Ramos López, Marco Alings, Sigrun Halvorsen, Roger M. Correa Flores, Andrzej Budaj, Joao Morais, Maria Dorobantu, Yuri Karpov, Arsen D. Ristic, Terrance Chua, Zlatko Fras, Anthony J. Dalby, H. Asita de Silva, Emil Hagström, Ulf Landmesser, Chern-En Chiang, Piyamitr Sritara, Sema Guneri, Alexander Parkhomenko, Kausik K. Ray, Patrick M. Moriarty, Robert Vogel, Bernard Chaitman, Sheryl F. Kelsey, Anders G. Olsson, Jean-Lucien Rouleau, Maarten L. Simoons, Karen Alexander, Chiara Meloni, Robert Rosenson, Eric J.G. Sijbrands, John H. Alexander, Luciana Armaganijan, Akshay Bagai, Maria Cecilia Bahit, J. Matthew Brennan, Shaun Clifton, Adam D. 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Detlev Schellenberg, Thomas Heitzer, Ulrich Laufs, Christian Werner, Stephan Gielen, Sebastian Nuding, Bernhard Winkelmann, Steffen Behrens, Karsten Sydow, Mahir Karakas, Gregor Simonis, Thomas Muenzel, Nikos Werner, Stefan Leggewie, Dirk Böcker, Rüdiger Braun-Dullaeus, Nicole Toursarkissian, Michael Jeserich, Matthias Weißbrodt, Tim Schaeufele, Joachim Weil, Heinz Völler, Johannes Waltenberger, Mohammed Natour, Susanne Schmitt, Dirk Müller-Wieland, Stephan Steiner, Lothar Heidenreich, Elmar Offers, Uwe Gremmler, Holger Killat, Werner Rieker, Sotiris Patsilinakos, Athanasios Kartalis, Athanassios Manolis, Dimitrios Sionis, Geargios Chachalis, Ioannis Skoumas, Vasilios Athyros, Panagiotis Vardas, Frangkiskos Parthenakis, Dimitrios Alexopoulos, Georgios Hahalis, John Lekakis, Apostolos Hatzitolios, Sergio R Fausto Ovando, Juan L Arango Benecke, Edgar R Rodriguez De Leon, Bryan PY Yan, David CW Siu, Tibor Turi, Bela Merkely, Imre Ungi, Geza Lupkovics, Lajos Nagy, András Katona, István 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Kultursay, H, Mutlu, B, Ersanli, M, Demirtas, M, Kirma, C, Ural, E, Koldas, L, Karpenko, O, Prokhorov, A, Vakaluyk, I, Myshanych, H, Reshotko, D, Batushkin, V, Rudenko, L, Kovalskyi, I, Kushnir, M, Tseluyko, V, Mostovoy, Y, Stanislavchuk, M, Kyiak, Y, Karpenko, Y, Malynovsky, Y, Klantsa, A, Kutniy, O, Amosova, E, Tashchuk, V, Leshchuk, O, Rishko, M, Kopytsya, M, Yagensky, A, Vatutin, M, Bagriy, A, Barna, O, Ushakov, O, Dzyak, G, Goloborodko, B, Rudenko, A, Zheleznyy, V, Trevelyan, J, Zaman, A, Lee, K, Moriarty, A, Aggarwal, R, Clifford, P, Wong, Y, Iqbal, S, Subkovas, E, Braganza, D, Sarkar, D, Storey, R, Griffiths, H, Mcclure, S, Muthusamy, R, Smith, S, Kurian, J, Levy, T, Barr, C, Kadr, H, Gerber, R, Simaitis, A, Soran, H, Mathur, A, Brodison, A, Ayaz, M, Cheema, M, Oliver, R, Thackray, S, Mudawi, T, Rahman, G, Sultan, A, Sharman, D, Sprigings, D, Butler, R, Wilkinson, P, Lip, G, Halcox, J, Gallagher, S, Ossei-Gerning, N, Vardi, G, Baldari, D, Brabham, D, Treasure II, C, Dahl, C, Palmer, B, Wiseman, A, Puri, S, Mohart, A, Ince, C, Flores, E, Wright, S, Cheng, S, Rosenberg, M, Rogers, W, Kosinski, E, Forgosh, L, Waltman, J, Khan, M, Shoukfeh, M, Dagher, G, Cambier, P, Lieber, I, Kumar, P, East, C, Krichmar, P, Hasan, M, White, L, Knickelbine, T, Haldis, T, Gillespie, E, Amidon, T, Suh, D, Arif, I, Abdallah, M, Akhter, F, Carlson, E, D'Urso, M, El-Ahdab, F, Nelson, W, Moriarty, K, Harris, B, Cohen, S, Carter, L, Doty, D, Sabatino, K, Haddad, T, Malik, A, Rao, S, Mulkay, A, Jovin, I, Klancke, K, Malhotra, V, Devarapalli, S, Koren, M, Chandna, H, Dodds III, G, Goraya, T, Bengston, J, Janik, M, Moran, J, Sumner, A, Kobayashi, J, Davis, W, Yazdani, S, Pasquini, J, Thakkar, M, Vedere, A, Leimbach, W, Rider, J, Fenton, S, Singh, N, Shah, A, Janosik, D, Pepine, C, Berman, B, Gelormini, J, Daniels, C, Richard, K, Keating, F, Kondo, N, Shetty, S, Levite, H, Waider, W, Takata, T, Abu-Fadel, M, Shah, V, Izzo, M, Kumar, A, Hattler, B, Do, R, Link, C, Bortnick, A, Kinzfogl III, G, Ghitis, A, Larry, J, Teufel, E, Kuhlman, P, Mclaurin, B, Zhang, W, Thew, S, Abbas, J, White, M, Islam, O, Subherwal, S, Ranadive, N, Vakili, B, Gring, C, Henderson, D, Schuchard, T, Farhat, N, Kline, G, Mahal, S, Whitaker, J, Speirs, S, Andersen, R, Daboul, N, Horwitz, P, Zahr, F, Ponce, G, Jafar, Z, Mcgarvey, J, Panchal, V, Voyce, S, Blok, T, Sheldon, W, Azizad, M, Schmalfuss, C, Picone, M, Pederson, R, Herzog, W, Friedman, K, Lindsey, J, Nowins, R, Timothy, E, Leonard, P, Lepor, N, El Shahawy, M, Weintraub, H, Irimpen, A, Alonso, A, May, W, Christopher, D, Galski, T, Chu, A, Mody, F, Ramin, E, Hodes, Z, Rossi, J, Rose, G, Fairlamb, J, Lambert, C, Raisinghani, A, Abbate, A, Vetrovec, G, King, M, Carey, C, Gerber, J, Younis, L, Vidovich, M, Knutson, T, Friedman, D, Chaleff, F, Loussararian, A, Rozeman, P, Kimmelstiel, C, Kuvin, J, Silver, K, Foster, M, Tonnessen, G, Espinoza, A, Amlani, M, Wali, A, Malozzi, C, Jong, G, Massey, C, Wattanakit, K, O'Donnell, P, Singal, D, Jaffrani, N, Banuru, S, Fisher, D, Xenakis, M, Perlmutter, N, Bhagwat, R, Strader, J, Blonder, R, Akyea-Djamson, A, Labroo, A, Marais, H, Claxton, E, Weiss, R, Kathryn, R, Berk, M, Joshi, P, Khera, A, Khaira, A, Kumkumian, G, Lupovitch, S, Purow, J, Welka, S, Hoffman, D, Fischer, S, Soroka, E, Eagerton, D, Pancholy, S, Ray, M, Erenrich, N, Farrar, M, Pollock, S, French, W, Diamantis, S, Guy, D, Gimple, L, Neustel, M, Schwartz, S, Pereira, E, Albert, S, Spriggs, D, Strain, J, Mittal, S, Vo, A, Chane, M, Hall, J, Vijay, N, Lotun, K, Lester, F, Nahhas, A, Pope, T, Nager, P, Vohra, R, Sharma, M, Bashir, R, Ahmed, H, Berlowitz, M, Fishberg, R, Barrucco, R, Yang, E, Radin, M, Sporn, D, Stapleton, D, Eisenberg, S, Landzberg, J, Mcgough, M, Turk, S, Schwartz, M, Sundram, P, Jain, D, Zainea, M, Bayron, C, Karlsberg, R, Dohad, S, Lui, H, Keen, W, Westerhausen, D, Khurana, S, Agarwal, H, Birchem, J, Penny, W, Chang, M, Murphy, S, Henry, J, Schifferdecker, B, Gilbert, J, Chalavarya, G, Eaton, C, Schmedtje, J, Christenson, S, Dotani, I, Denham, D, Macdonell, A, Gibson, P, Rahman, A, Al Joundi, T, Assi, N, Conrad, G, Kotha, P, Love, M, Giesler, G, Rubenstein, H, Gamil, D, Akright, L, Krawczyk, J, Cobler, J, Wells, T, Welker, J, Foster, R, Gilmore, R, Anderson, J, Jacoby, D, Gardner, G, Dandillaya, R, Vora, K, Kostis, J, Hunter, J, Laxson, D, Ball, E, Egydio, F, Kawakami, A, Oliveira, J, Wozniak, J, Matthews, A, Ratky, C, Valiris, J, Berdan, L, Hepditch, A, Quintero, K, Rorick, T, Westbrook, M, Pascual, A, Rovito, C, Bezault, M, Drouet, E, Simon, T, Alsweiler, C, Luyten, A, Butters, J, Griffith, L, Shaw, M, Grunberg, L, Islam, S, Bregeault, M, Bougon, N, Faustino, D, Fontecave, S, Murphy, J, Verrier, M, Agnetti, V, Andersen, D, Badreddine, E, Bekkouche, M, Bouancheau, C, Brigui, I, Brocklehurst, M, Cianciarulo, J, Devaul, D, Domokos, S, Gache, C, Gobillot, C, Guillou, S, Healy, J, Heath, M, Jaiwal, G, Javierre, C, Labeirie, J, Monier, M, Morales, U, Mrabti, A, Mthombeni, B, Okan, B, Smith, L, Sheller, J, Sopena, S, Pellan, V, Benbernou, F, Bengrait, N, Lamoureux, M, Kralova, K, Scemama, M, Bejuit, R, Coulange, A, Berthou, C, Repincay, J, Lorenzato, C, Etienne, A, Gouet, V, Normand, M, Ourliac, A, Rondel, C, Adamo, A, Beltran, P, Barraud, P, Dubois-Gache, H, Halle, B, Metwally, L, Mourgues, M, Sotty, M, Vincendet, M, Cotruta, R, Chengyue, Z, Fournie-Lloret, D, Morrello, C, Perthuis, A, Picault, P, Zobouyan, I, Dempsey, M, Mcclanahan, M, ODYSSEY OUTCOMES Comm Investigato, and Ege Üniversitesi
Subjects: Male, BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences, STATIN THERAPY, blood-glucose, Endocrinology, Diabetes and Metabolism, GUIDELINES, PCSK9, 0302 clinical medicine, Endocrinology, GENETIC-VARIANTS, Cardiovascular Disease, Diabetes Complication, Aged Antibodies, Monoclonal, Humanized / therapeutic use* Cardiovascular Diseases / blood Cardiovascular Diseases / prevention & control* Diabetes Complications / blood Diabetes Complications / prevention & control* Female Humans Male Middle Aged Substances, Clinical endpoint, Medicine, guidelines, 030212 general & internal medicine, Prediabetes, Myocardial infarction, myocardial-infarction, genetic-variants, statin therapy, risk, pcsk9, association, liraglutide, evolocumab, RISK, BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti, BLOOD-GLUCOSE, ASSOCIATION, Middle Aged, Cardiovascular Diseases, Female, Life Sciences & Biomedicine, Human, medicine.medical_specialty, Acute coronary syndrome, PCSK9 inhibitor, acute coronary syndrome, lipoprotein(a), low-density lipoprotein cholesterol, 030209 endocrinology & metabolism, Antibodies, Monoclonal, Humanized, Diabetes Complications, Endocrinology & Metabolism, 03 medical and health sciences, Diabetes mellitus, Internal medicine, Internal Medicine, Humans, Aged, Alirocumab, diabetes, PCSK9, hyperlipidemia, Science & Technology, ODYSSEY OUTCOMES Committees and Investigators, business.industry, Unstable angina, EVOLOCUMAB, medicine.disease, MYOCARDIAL-INFARCTION, LIRAGLUTIDE, Human medicine, business
Abstract: Doi, Yasuji/0000-0002-8368-0827; galvani, marcello/0000-0001-5897-667X; Gislason, Gunnar H/0000-0002-0548-402X; Taskinen, Marja-Riitta/0000-0002-6229-3588; Sherwood, Matthew/0000-0002-4305-5883; Malynovsky, Yaroslav V/0000-0002-9118-1104; Viktorova, vic-inna@mail.ru I.A./0000-0001-8728-2722; bastos, jose/0000-0002-9526-3123; Yang, Eric H/0000-0003-4889-7454; Rudenko, Anatoliy Viktorovich/0000-0003-1099-1613; Novotny, Vojtech/0000-0003-3521-9945; Nikolaev, Konstantin/0000-0003-4601-6203; Reshetko, Olga/0000-0003-3107-7636; Leonardi, Sergio/0000-0002-4800-6132; Muenzel, Thomas/0000-0001-5503-4150; Ushakov, Alexei V/0000-0002-7020-4442; Tse, Hung Fat/0000-0002-9578-7808; Podoleanu, Cristian/0000-0001-9987-2519; Raffel, Owen C/0000-0001-5470-7050; Khasanov, Niiaz/0000-0002-7760-0763; Chumakova, Galina A/0000-0002-2810-6531; Ersanli, Murat/0000-0003-1847-3087; cornel, jan hein/0000-0002-1006-2112; Abbate, Antonio/0000-0002-1930-785X; Racca, Vittorio/0000-0002-4465-3789; Urina-Triana, Miguel A/0000-0001-6003-4622; Rasputina, Lesia/0000-0003-1230-4039; Racca, Vittorio/0000-0002-4465-3789; Reis, Gilmar/0000-0002-4847-1034; Sandhu, Manjinder/0000-0003-2538-2079; Keskin, Kudret/0000-0002-9049-1530; PAREPA, IRINEL/0000-0002-7571-9015; Manakshe, Gajendra/0000-0002-4983-4271; Nicolau, Jose C/0000-0002-9680-3689; Strelnieks, Aldis/0000-0003-3493-2562; Budaj, Andrzej/0000-0002-6395-2098; Marin, Francisco/0000-0001-7246-7708; Wongpraparut, Nattawut/0000-0002-1541-3313; Yuan, Zuyi/0000-0002-4141-0298; Jeong, Myung Ho/0000-0003-2424-810X; Mostovoy, Yuriy/0000-0002-7041-1230; Pepine, Carl/0000-0002-6011-681X; Lopez-Jaramillo, Patricio/0000-0002-9122-8742; Garcia-Lledo, Alberto/0000-0002-8986-2584; Tesloianu, Nicolae-Dan/0000-0002-1007-3022; Kosmacheva, Elena/0000-0001-8600-0199; Kunz Sebba Barroso Souza, Weimar/0000-0002-1265-1930; Katz, Amos/0000-0003-0422-934X; Tunon, Jose/0000-0002-1373-0999; Acevedo, Monica/0000-0002-7989-6633; Hove, Jens/0000-0002-5600-5623; Yakushin, Sergey/0000-0001-7202-742X; Gonzalez Juanatey, Jose Ramon/0000-0001-9681-3388; Lyamina, Nadezhda/0000-0001-6939-3234; Aylward, Philip/0000-0002-5358-8552; Apostolovic, Svetlana/0000-0001-9015-297X; Airaksinen, Juhani/0000-0002-0193-568X; Nahhas, Prof. Dr. Ahmed/0000-0002-2887-8187; Barbarash, Olga/0000-0002-4642-3610, WOS: 000475553300016, PubMed: 31272931, Background After acute coronary syndrome, diabetes conveys an excess risk of ischaemic cardiovascular events. A reduction in mean LDL cholesterol to 1.4-1.8 mmol/L with ezetimibe or statins reduces cardiovascular events in patients with an acute coronary syndrome and diabetes. However, the efficacy and safety of further reduction in LDL cholesterol with an inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) after acute coronary syndrome is unknown. We aimed to explore this issue in a prespecified analysis of the ODYSSEY OUTCOMES trial of the PCSK9 inhibitor alirocumab, assessing its effects on cardiovascular outcomes by baseline glycaemic status, while also assessing its effects on glycaemic measures including risk of new-onset diabetes. Methods ODYSSEY OUTCOMES was a randomised, double-blind, placebo-controlled trial, done at 1315 sites in 57 countries, that compared alirocumab with placebo in patients who had been admitted to hospital with an acute coronary syndrome (myocardial infarction or unstable angina) 1-12 months before randomisation and who had raised concentrations of atherogenic lipoproteins despite use of high-intensity statins. Patients were randomly assigned (1: 1) to receive alirocumab or placebo every 2 weeks; randomisation was stratified by country and was done centrally with an interactive voice-response or web-response system. Alirocumab was titrated to target LDL cholesterol concentrations of 0.65-1.30 mmol/L. in this prespecified analysis, we investigated the effect of alirocumab on cardiovascular events by glycaemic status at baseline (diabetes, prediabetes, or normoglycaemia)-defined on the basis of patient history, review of medical records, or baseline HbA(1c) or fasting serum glucose-and risk of new-onset diabetes among those without diabetes at baseline. the primary endpoint was a composite of death from coronary heart disease, non-fatal myocardial infarction, fatal or non-fatal ischaemic stroke, or unstable angina requiring hospital admission. ODYSSEY OUTCOMES is registered with ClinicalTrials. gov, number NCT01663402. Findings At study baseline, 5444 patients (28.8%) had diabetes, 8246 (43.6%) had prediabetes, and 5234 (27.7%) had normoglycaemia. There were no significant differences across glycaemic categories in median LDL cholesterol at baseline (2.20-2.28 mmol/L), after 4 months' treatment with alirocumab (0.80 mmol/L), or after 4 months' treatment with placebo (2.25-2.28 mmol/L). in the placebo group, the incidence of the primary endpoint over a median of 2.8 years was greater in patients with diabetes (16.4%) than in those with prediabetes (9.2%) or normoglycaemia (8.5%); hazard ratio (HR) for diabetes versus normoglycaemia 2.09 (95% CI 1.78-2.46, p, Sanofi; Regeneron Pharmaceuticals, Sanofi and Regeneron Pharmaceuticals.
Published: 2019
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28. Fine-scale population fragmentation of a grassland butterfly Plebejus argyrognomon inhabiting agricultural field margin and riverbank in rural landscapes.

Author: Tadashi MIYASHITA, Fuga MATSUI, Hidenori DETO, Tatsuya IMAI, and Natsuko I. KONDO
Subjects: GENETIC variation, RIPARIAN areas, GRASSLANDS, GENETIC drift, FRAGMENTED landscapes, GRASSLAND soils, HABITATS
Abstract: Evaluating the spatial genetic structure of rare species is important because it could provide information on the degree of habitat fragmentation and effective population size that are necessary for conservation planning. We examined the genetic structure of the grassland butterfly Plebejus argyrognomon that has severely declined in recent decades using single nucleotide polymorphisms obtained by the MIG-seq method. The study region was in the southern Ina Basin located in central Japan, where P. argyrognomon inhabits grasslands in agricultural field margin as well as in riverbank. We found a positive association between genetic and geographic distances, but the pattern was nonlinear, with little change in genetic distance above 12 km. The genetic differentiation was considerable, as demonstrated by FST and Structure. Moreover, genetic diversity was positively associated with habitat connectivity index, suggesting severe genetic drift in isolated populations. Comparing two habitat types, the genetic structure tended to be similar among agricultural field margin populations while dissimilar among riverbank populations, suggesting frequent gene flow in the former. Coupled with the presence of many habitat patches in agricultural field margin, we consider that agricultural field margin populations in the northern part of the study sites appear valuable to ensure long-term persistence of the regional P. argyrognomon population. [ABSTRACT FROM AUTHOR]
Published: 2021
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29. DNA barcoding supports reclassification of JapaneseChironomusspecies (Diptera: Chironomidae)

Author: Veronika V. Golygina, Kenzi Takamura, Ryuhei Ueno, Natsuko I. Kondo, and Kako Ohbayashi
Subjects: 0106 biological sciences, 0301 basic medicine, biology, Phylogenetic tree, Zoology, biology.organism_classification, 010603 evolutionary biology, 01 natural sciences, DNA barcoding, Chironomidae, 03 medical and health sciences, 030104 developmental biology, Genus, Abundance (ecology), Insect Science, Chironomus, Bioindicator, Ecology, Evolution, Behavior and Systematics
Abstract: Non-biting midges (Diptera: Chironomidae) adapt to species-specific environmental conditions and hence are promising bioindicators for aquatic and ecotoxicological monitoring. Although their utility for these purposes was historically limited by difficulties in their morphological identification, DNA barcoding offers a possible solution. Here, eight Japanese species of the genus Chironomus, which is characterized by its worldwide distribution and abundance among Chironomidae, were subjected to DNA barcoding using cytochromec oxidase subunit I (COI). To examine whether this DNA barcode is a useful indicator for Japanese species of Chironomus, we calculated genetic distances within and between the COI sequences of Chironomus species both from this study and worldwide and constructed phylogenetic trees. Based on 415 bp COI sequences and the Kimura two-parameter model, the average genetic distances within 37 species and between 72 species were 2.6% and 17.2%, respectively. Although the ranges of genetic distances within and between species overlapped from 0.8% to 17.3%, 99.7% of average genetic distances between species were >3.0%. Some of this overlap is attributable to distances within species that were “too large” as well as those between species that were “too small”. Of eight Japanese species examined, two showed genetic distances between species that were below a 3.0% threshold, and four had distances within species that were greater than 3.0%. These results suggest a possible reclassification of these species and the need for further sampling to unveil biogeographic variations among different countries and regions.
Published: 2016
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30. DNA-sequence-based species delimitation for larval chironomid samples collected from Japanese farm ponds

Author: Ryuhei Ueno, Kako Ohbayashi, Kenzi Takamura, and Natsuko I. Kondo
Subjects: 0106 biological sciences, 0301 basic medicine, 03 medical and health sciences, Larva, 030104 developmental biology, Ecology, Zoology, Aquatic Science, Biology, 010603 evolutionary biology, 01 natural sciences, DNA sequencing, Water Science and Technology
Published: 2016
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31. Morphospecies does not match DNA barcoding results in a some common Japanese chironomid species

Author: Natsuko I. Kondo, Kenzi Takamura, Ryuhei Ueno, Shiori Okuda, and Kako Ohbayashi
Subjects: Thesaurus (information retrieval), Geography, Information retrieval, Ecology, Aquatic Science, DNA barcoding, Genealogy, Water Science and Technology
Published: 2016
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32. Comparison of DNA extraction methods for DNA barcoding of non-biting midges

Author: Natsuko I. Kondo, Ryuhei Ueno, Kako Ohbayashi, Kenzi Takamura, and Shiori Okuda
Subjects: Biting, Ecology, Zoology, Aquatic Science, Biology, Bioinformatics, DNA barcoding, DNA extraction, Gene, Water Science and Technology
Published: 2016
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33. MON-034 A case of frequent relapse minimal change nephrotic syndrome with steroid-induced psychiatric syndromes treated by a low-dose and short-term steroid therapy in combination with cyclosporine

Author: H. Beppu, Fumihiko Hinoshita, Manami Tada, S. Emi, Y. Mitani, I. Kondo, Daisuke Katagiri, S. Shioji, and Y. Arai
Subjects: medicine.medical_specialty, Steroid therapy, Nephrology, business.industry, Internal medicine, medicine.medical_treatment, Low dose, medicine, Minimal change nephrotic syndrome, business, Gastroenterology, Steroid
Published: 2019
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34. The generalized BBM-Burgers equations: convergence results for conservation law with discontinuous flux function

Author: Cezar I. Kondo and Claudete M. Webler
Subjects: Sequence, Conservation law, Partial differential equation, Applied Mathematics, 010102 general mathematics, Mathematical analysis, Flux, Function (mathematics), 01 natural sciences, 010101 applied mathematics, Compact space, Convergence (routing), 0101 mathematics, Analysis, Mathematics
Abstract: We consider conservation laws with discontinuous flux, which are regularized with generalized BBM-Burgers equations. We study the convergence of one sequence of solutions of these equations for one solution of the associated conservation law. In the multidimensional case, we prove one convergence result using the H-measures and in the one-dimensional case, we use the method of compensated compactness.
Published: 2015
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35. RASCH analysis for the recovery process for patients of persistent vegetative state using the National Agency for automotive safety and victims’ aid (NASVA) score

Author: K. Sato, Y. Nagamine, Jun Shinoda, C. Honda, I. Kondo, E. Takano, and Toshio Teranishi
Subjects: Rehabilitation, Rasch model, medicine.medical_treatment, Process (computing), Cognition, Automotive safety, behavioral disciplines and activities, Statistics, medicine, Psychometric software, Raw score, Orthopedics and Sports Medicine, Set (psychology), Psychology
Abstract: Introduction/Background The purpose of this study was to analyze NASVA scores using Rasch analysis, and to create a difficulty map of NASVA score to predict the recovery process for persistent vegetative state, and to improve the fitness of the sub-items of NASVA score. Material and method Participants were 114 inpatients (mean age, 37.4 ± 20.4 years) who had been diagnosed with persistent vegetative state after a traffic accident. Rasch analysis was performed by an application named “winsteps”. This application produces a score table, an item measure of the sub-items containing an information-weighted mean square fit statistics (infit) and an outlier-sensitive mean square fit statistics (outfit) of the sub-items. First, I replaced NASVA score with the binary score. Rasch analysis provided a scaled score corresponding to the binary score. The raw score was the sum of the binary score of the sub-item. Then, I made the difficulty map using the scaled score that was calculated in winsteps as the item measure. Furthermore, I analyzed the fitness of the sub-items for the recovery process for persistent vegetative state using their infit and outfit. Here, I set 1.5 or more as misfits for infit or outfit of sub-items. Results In the results of the fitness analysis, nine sub-items were identified as misfits: one motor function, three feeding functions, one excretory function, one cognitive function, and three articulatory and utterance functions. Conclusion Nine misfit sub-items had room for interpretation depending on the insufficient of the items description. Therefore, it was suggested that we improve the scale by removing sub-items from the NASVA score, or creating an interpretation manual. On the other hands, by making use of the difficulty map of NASVA score, the medical staff might be able to decide on the proper goals of rehabilitation and care according to the recovery process of the patient.
Published: 2018
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36. MON-026 A THERAPEUTIC RECOMMENDATION FOR MEMBRANOUS NEPHROPATHY ASSOCIATED WITH CHRONIC GRAFT-VERSUS-HOST DISEASE AFTER ALLOGENEIC PERIPHERAL BLOOD STEM CELL TRANSPLANTATION

Author: Y. Arai, Y. Minani, E. Sakamoto, Manami Tada, H. Beppu, I. Kondo, Daisuke Katagiri, Fumihiko Hinoshita, and S. Shioji
Subjects: Pathology, medicine.medical_specialty, Graft-versus-host disease, Membranous nephropathy, Nephrology, business.industry, medicine, Peripheral Blood Stem Cell Transplantation, medicine.disease, business
Published: 2019
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37. Biological pest control by investing crops in pests

Author: Hiroshi C. Ito and Natsuko I. Kondo
Subjects: Crop, education.field_of_study, Agronomy, Population, Biological pest control, PEST analysis, Biology, education, Predator, System structure, Ecology, Evolution, Behavior and Systematics, Predation
Abstract: We propose a biological pest control system that invests part of a crop in feeding a pest in a cage. The fed pest maintains a predator that attacks the pest in the target area (i.e., the area for storing or growing crops). The fed pest cannot leave the cage nor the target pest cannot enter the cage. The predator, however, can freely attack both the fed and target pests in the target area. By introducing a refuge in the cage against the predator for the fed pest, the fed pest and predator may be stably sustained. In this study, we analyzed the potential performance of this system by modeling the population dynamics of the target pest, fed pest, and predator as differential equations. First, we show analytically that the target pest can be suppressed at extremely low abundance by adjusting both refuge efficiency and crop investment. Second, we show numerically that crop damage by the pest may be effectively suppressed by investing only small amounts of the crop. Third, we show numerically that the magnitude of required crop investment can be estimated by an index comprising of the predator’s searching cost for prey and the relative growth efficiency of the predator with respect to the pest. Even if the system structure is changed or its population dynamics is modeled based on host–parasitoid interactions, crop damage can be suppressed effectively by small amounts of crop investment.
Published: 2012
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38. WolbachiaInfections in World Populations of Bean Beetles (Coleoptera: Chrysomelidae: Bruchinae) Infesting Cultivated and Wild Legumes

Author: Yukihiko Toquenaga, Masakazu Shimada, Takema Fukatsu, Midori Tuda, Yen Chiu Lan, Natsuko I. Kondo, Sawai Buranapanichpan, and Shwu Bin Horng
Subjects: Crops, Agricultural, DNA, Bacterial, Species complex, Asia, food.ingredient, Middle East, food, parasitic diseases, Botany, Animals, Uganda, Rhynchosia minima, Phylogeny, reproductive and urinary physiology, biology, Host (biology), business.industry, Pest control, food and beverages, Fabaceae, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, Coleoptera, Callosobruchus, bacteria, Animal Science and Zoology, Wolbachia, business, Genetic isolate, Cytoplasmic incompatibility
Abstract: Wolbachia endosymbionts are widespread among insects and other arthropods, often causing cytoplasmic incompatibility and other reproductive phenotypes in their hosts. Recently, possibilities of Wolbachia-mediated pest control and management have been proposed, and the bean beetles of the subfamily Bruchinae are known as serious pests of harvested and stored beans worldwide. Here we investigated Wolbachia infections in bean beetles from the world, representing seven genera, 20 species and 87 populations. Of 20 species examined, Wolbachia infections were detected in four species, Megabruchidius sophorae, Callosobruchus analis, C. latealbus and C. chinensis. Infection frequencies were partial in M. sophorae but perfect in the other species. In addition to C. chinensis described in the previous studies, C. latealbus was infected with two distinct Wolbachia strains. These Wolbachia strains from the bean beetles were phylogenetically not closely related to each other. Among world populations of C. chinensis, some Taiwanese populations on a wild leguminous plant, Rhynchosia minima, exhibited a peculiar Wolbachia infection pattern, suggesting the possibility that these populations comprise a distinct host race or a cryptic species.
Published: 2011
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39. Can side predict the fall after discharge for the patients after surgery for proximal femoral fracture?

Author: N. Morioka, Y. Mizuno, K. Ito, E. Takano, I. Kondo, K. Sato, and N. Itoh
Subjects: Predictive validity, medicine.medical_specialty, Mini–Mental State Examination, Rehabilitation, medicine.diagnostic_test, Home environment, business.industry, medicine.medical_treatment, Odds ratio, Femoral fracture, After discharge, medicine.disease, Surgery, medicine.anatomical_structure, Medicine, Orthopedics and Sports Medicine, business, Femoral neck
Abstract: Introduction/Background Standing balance test for imbalance and disequilibrium (SIDE) was developed as a predictive measure for the fall prevention of the patients in hospital. Excellent predictive validity of SIDE was defined with the patients who admitted to reminiscence rehabilitation ward. On the other hand, the prevention of fall after discharge for the patients with fracture is essential to avoid recurrence of fracture. In this study, we use SIDE to predict fall event after the discharge for the patients after the surgery for proximal femoral fracture. Material and method Participants of this study were the patients who discharged and returned to home from reminiscence rehabilitation ward after the surgery for proximal femoral fracture during the period from April, 2014 to September 2016. They were 10 male and 35 female patients and their average age was 78.3 (SD: 8.9). We sent questionnaire about the fall event and recurrence of fracture. Multiple logistic regression analysis was performed with age, duration of admission, the result of Mini Mental State Examination, FIM, SIDE and comfortable gait velocity at discharge as the independent factor according to the fall event occurrence. Results The fall event was occurred for seven patients (15.6%). Two of them (4.4%) experienced recurrence of fracture at femoral neck and vertebral body. SIDE (P = 0.049) and comfortable gait velocity (P = 0.027) had the significant effect on fall event and their odds ratio and 90% confidential interval were 0.32 (0.11 − 0.99) and 1119.47 (2.18 − 574866.87), respectively. Conclusion In addition to comfortable gait velocity, SIDE was the significant factor to predict the fall event for the one year after discharge. Cutting point of comfortable gait velocity would be warranted to use it as predictive measure. Discreet selection of walking aids and modification of home environment are necessary for the patients with high fall risk detected by SIDE.
Published: 2018
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40. Correlation between the Quality of Life after Brain Injury in Japanese version (QOLIBRI-J) and Community Integration Questionnaire (CIQ)

Author: Megumi Suzuki, K. Ota, Mariko Naito, and I. Kondo
Subjects: Disease specific, Traumatic brain injury, business.industry, Rehabilitation, Community integration, medicine.disease, Spearman's rank correlation coefficient, Correlation, Cronbach's alpha, Quality of life, medicine, Orthopedics and Sports Medicine, Low correlation, business, Clinical psychology
Abstract: Introduction/Background The Quality of Life after Brain Injury (QOLIBRI; 37 items) is a disease specific subjective questionnaire of health-related quality of life (HRQoL) in persons after traumatic brain injury. We developed Japanese version of QOLIBRI; QOLIBRI-J and reported that it's test-retest reliability (ICC; 0.92, Cronbach α = 0.86) and validity (Correlations of SF-36) were excellent. The Questionnaires of QOLIBRI-J are based on subjective satisfaction, although those of another popular QOL instrument, Community Integration Questionnaire; CIQ is based on objective situations. We investigated between the relationship of QOLIBRI-J and CIQ of the persons with higher brain dysfunctions after TBI to show the differences of subjective and objective QOL. Material and method Subjects: 73 recruited community-dwelling Japanese with higher brain dysfunction after traumatic brain injury [61 male, 12 female: age 41.6 ± 14.3, Glasgow Outcome Scale-Extended; GOSE (3 to 8: median 5)]. Design The Correlations between QOLIBRI-J and CIQ were investigated in 73 subjects at the same time. They were also asked to fill the GOSE. The questionnaires were administered in one of three modes: by self-report (mail), self-report (participant presents at the clinic), and face-to-face interview. Results Distribution of GOS-E score were as follows, 3: lower severe disability (12.3%), 4: upper severe disability (27.4%), 5: lower moderate disability (27.4%), 6: upper moderate disability (16.4%), 7: lower good recovery (11.0%), 8: upper good recovery (5.5%). There was a low correlation between QOLIBRI-J total score and the CIQ total score (ρ=0.326 Spearman correlation coefficient). By the subscale analysis, the strongest correlation was found between QOLIBRI-J (Daily life/autonomy) and CIQ (social life). In contrast there was the weakest correlation between QOLIBRI (emotions) and CIQ (productive life). There was no correlation between the QOLIBRI and GOSE (ρ=0.21). Conclusion QOLIBRI-J had a mild correlation with CIQ. There were some differences between QOLIBI and CIQ. One of the reasons of this difference was thought to be the subjective emotional factor about taking a productive work.
Published: 2018
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41. Higher order for the generalized BBM-burgers equation: existence and convergence results

Author: Claudete M. Webler and Cezar I. Kondo
Subjects: Conservation law, Partial differential equation, Applied Mathematics, Mathematical analysis, Convergence (routing), First-order partial differential equation, Zero (complex analysis), Order (group theory), Hyperbolic partial differential equation, Analysis, Mathematics, Burgers' equation
Abstract: We study the global existence of solutions for certain equations of the form as δ > 0 and γ n > 0, n = 1, …, N approach zero, and f is a sufficiently smooth function satisfying certain appropriate assumptions. We consider solutions of hyperbolic conservation laws regularized of these equations. Following a pioneering work by Schonbek and a work by LeFloch and Natalini, we establish the convergence of the regularized solutions towards discontinuous solutions of the hyperbolic conservation law.
Published: 2009
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42. Higher-Order for the Multidimensional Generalized BBM-Burgers Equation: Existence and Convergence Results

Author: Claudete M. Webler and Cezar I. Kondo
Subjects: Combinatorics, Cauchy problem, Partial differential equation, Applied Mathematics, Mathematical analysis, Uniqueness, Burgers' equation, Mathematics
Abstract: We study the global existence of solutions for the multidimensional generalized BBM-Burgers equations of the form $$u_t+\sum_{j=1}^{d}f_j(u)_{x_j}=\delta\sum_{j=1}^{d}u_{x_jx_jt}+\sum_{j=1}^{d}\Biggl(\sum_{n=1}^{N}(-1)^{n+1}\gamma_n\partial_{x_j}^{2n}u\Biggr),$$ for (x,t)∈ℝd×ℝ+, with initial data u(x,0)=u0(x), x∈ℝd, as α>0, γn>0, n=1,…,N approach zero, and f is a sufficiently smooth function. We also deal with the convergence of solutions of this Cauchy problem, and the proofs are based instead on DiPerna’s uniqueness theory for entropy measure-valued solutions.
Published: 2009
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43. A NONLINEAR PARABOLIC APPROXIMATION OF THE EULER EQUATIONS FOR ISOTHERMAL GAS FLOWS

Author: Cezar I. Kondo and Vladimir Shelukhin
Subjects: Nonlinear system, symbols.namesake, Compact space, General Mathematics, Mathematical analysis, symbols, Shock front, Conservation of mass, Analysis, Isothermal process, Mathematics, Euler equations
Abstract: A notion of entropy quasisolution is introduced for the Euler equations of isothermal gas flows. Such a solution is obtained by means of nonlinear parabolic approximation with a small parameter ε. Compensated compactness argument is applied to justify the passage to limit as ε → 0 for the case when the mass density is strictly positive. It is verified that smooth entropy quasisolution is necessarily a classic solution. An example of entropy solution with a shock front is constructed to reveal that it is not an entropy quasisolution. The study is motivated by the explosion physics experiments in which the mass conservation law may be violated at a shock front passing through the gas.
Published: 2008
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44. The generalized BBM-Burger equations with non-linear dissipative term: existence and convergence results

Author: Cezar I. Kondo and Claudete M. Webler
Subjects: Nonlinear system, Conservation law, Work (thermodynamics), Partial differential equation, Applied Mathematics, Mathematical analysis, Convergence (routing), Dissipative system, Zero (complex analysis), Hyperbolic partial differential equation, Analysis, Mathematical physics, Mathematics
Abstract: We study the global existence of solutions for certain equations of the form u t + f(u) x = γB(u x ) x + δu xxt − αu xxxx , as γ > 0, δ > 0 and α > 0 aproach zero, and f and B are sufficiently smooth functions satisfying certain appropriate assumptions. We consider solutions of hyperbolic conservation laws regularized of this equations. Following a pioneering work by Schonbek and a work by LeFloch and Natalini, we establish the convergence of the regularized solutions towards discontinuous solutions of the hyperbolic conservation law.
Published: 2008
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45. A massive tsunami promoted gene flow and increased genetic diversity in a near threatened plant species

Author: Ohbayashi, Kako, primary, Hodoki, Yoshikuni, additional, I. Kondo, Natsuko, additional, Kunii, Hidenobu, additional, and Shimada, Masakazu, additional
Published: 2017
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46. Non-local parabolic systems: applications in the three-phase capillary fluid filtration

Author: V. V. Shelukhin and C. I. Kondo
Subjects: Physics::Fluid Dynamics, Physics, Class (set theory), Three-phase, Pressure control, Capillary action, Applied Mathematics, Degenerate energy levels, Mathematical analysis, Mathematics::Analysis of PDEs, Inflow, Fluid filtration, Porous medium
Abstract: Non-local degenerate parabolic systems arise in three-phase capillary flows in porous media under a pressure control at the inflow- and outflow-boundaries. A mathematical study of such systems is performed for a class of capillarity pressure functions corresponding to triangular capillarity-diffusion tensors. To this end a theory of non-degenerate parabolic approximations is developed: the unique global solvability of initial boundary-value problems is proved.
Published: 2005
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47. Which infertile women should be indicated for sonohysterography?

Author: Shigeru Toda, Hisao Ando, I. Kondo, Tetsuo Masahashi, Shigehiko Mizutani, M. Harada, and S. Yoshida
Subjects: Infertility, Gynecology, medicine.medical_specialty, Radiological and Ultrasound Technology, business.industry, Obstetrics and Gynecology, Uterine bleeding, General Medicine, medicine.disease, Asymptomatic, Lesion, Transvaginal ultrasound, Reproductive Medicine, Follicular phase, medicine, Endometrial Polyp, Outpatient clinic, Radiology, Nuclear Medicine and imaging, medicine.symptom, business
Abstract: Objective To evaluate the indications for transvaginal saline contrast sonohysterography (TV-SCSH) in endometrial screening by transvaginal sonography in infertile women. Methods The study involved 850 consecutive infertile women presenting to an outpatient clinic. Using transvaginal ultrasound endometrial images were evaluated in the proliferative phase. Abnormal images were classified as follows: rugged (R), hyperechoic (H), waved (W), or thick (T). Clinical symptoms such as hypermenorrhea, dysmenorrhea and abnormal uterine bleeding were also recorded. Abnormal endometrial images were further evaluated on TV-SCSH. Age-matched women with normal endometrial images underwent TV-SCSH as controls. Results The endometrial pattern was abnormal in 111 patients (13.1%). Lesions that had been identified by TV-SCSH including endometrial polyps (44 cases), submucosal myomata (29 cases), and intramural myomata with mucosal extension (24 cases) were largely associated with the R and/or the H pattern, the W or the T pattern, and the W pattern, respectively. Sensitivity and specificity of the abnormal endometrial image for any lesion were 100% and 91.5%, respectively. Sixty-four patients (59.3%) were asymptomatic despite an abnormal endometrial image. Conclusions TV-SCSH should be performed on selected patients following assessment of endometrial images on transvaginal sonography in order to diagnose intra- and pericavitary lesions in infertile women. Copyright © 2004 ISUOG. Published by John Wiley & Sons, Ltd.
Published: 2004
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48. Zero Diffusion-Dispersion Limits for Scalar Conservation Laws

Author: Philippe G. LeFloch and Cezar I. Kondo
Subjects: Cauchy problem, Computational Mathematics, Conservation law, Partial differential equation, Compact space, Uniqueness theorem for Poisson's equation, Applied Mathematics, Mathematical analysis, A priori estimate, Entropy (arrow of time), Analysis, Mathematics, Burgers' equation
Abstract: We consider solutions of hyperbolic conservation laws regularized with vanishing diffusion and dispersion terms. Following a pioneering work by Schonbek, we establish the convergence of the regularized solutions toward discontinuous solutions of the hyperbolic conservation law. The proof relies on the method of compensated compactness in the L2 setting. Our result improves upon Schonbek's earlier results and provides an optimal condition on the balance between the relative sizes of the diffusion and the dispersion parameters. A convergence result is also established for multidimensional conservation laws by relying on DiPerna's uniqueness theorem for entropy measure-valued solutions.
Published: 2002
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49. Relationship between muscle strength and knee pain in knee osteoarthritis patients

Author: T. Nemoto, R. Fujita, I. Kondo, M. Takemura, Susumu Ota, Yasumoto Matsui, and A. Harada
Subjects: musculoskeletal diseases, medicine.medical_specialty, Rehabilitation, business.industry, Stair climbing, medicine.medical_treatment, Biomedical Engineering, Osteoarthritis, musculoskeletal system, Sitting, medicine.disease, Nursing care, Knee pain, medicine.anatomical_structure, Rheumatology, Orthopedic surgery, medicine, Physical therapy, Orthopedics and Sports Medicine, medicine.symptom, Ankle, business, human activities
Abstract: s / Osteoarthritis and Cartilage 22 (2014) S57–S489 S415 747 RELATIONSHIP BETWEEN MUSCLE STRENGTH AND KNEE PAIN IN KNEE OSTEOARTHRITIS PATIENTS R. Fujita y, Y. Matsui y, A. Harada y, M. Takemura y, I. Kondo z, T. Nemoto x, S. Ota k. yDept. of Orthopaedic Surgery, Natl. Ctr. for Geriatrics and Gerontology, Obu, Japan; zDept. of Rehabilitation Med., Natl. Ctr. for Geriatrics and Gerontology, Obu, Japan; xDept. of Gerontechnology, Natl. Ctr. for Geriatrics and Gerontology, Obu, Japan; k Seijoh Univ., Tokai, Japan Purpose: Knee osteoarthritis is a motor disorder that leads to decreased QOL and physical function in old age, and is one cause of the need for nursing care. The prevention of knee osteoarthritis and amelioration of its symptoms are an urgent issue today with rapidly increasing elderly populations. The importance of knee muscle strength training in conservative treatment is well known, and it effects have been verified. To elucidate the relationship between muscle strength and pain symptoms, we investigated the relationship between muscle strength, measured with a knee extension and flexion strength measurement instrument we are currently developing, and knee pain in activities of daily living. Methods: The subjects were 92 women (mean age 73.8 8.6 years) with knee osteoarthritis who were being treated in the orthopedics department of our center, comprising 160 knees (right 75, left 85) that had not been treated surgically. Standing frontal X-ray images of the knee were evaluated and knee pain during activities of daily living (level ground walking, stair climbing, lying down, standing up, and sitting on floor with legs folded underneath the body) was surveyed with a questionnaire. Knee extension and flexion strength was measured using a prototype measuring instrument developed jointly with the Department of Gerontechnology at our center. The knee extension and flexion measuring instrument can be transported on a cart, and uses an Imada Co., Ltd. force gauge for measuring the precision of industrial products. With subjects in a sitting position with legs flexed 90 and a strap on the ankle joint, knee extension and flexion strength were measured isometrically for 3 seconds. Knee flexion strength and extension strength were measured two times each in the left and right legs and the better value for each side was utilized. Knee extension and flexion strength were expressed as the proportion to body weight, and the difference of the two, (extension strength/weight) minus (flexion strength/weight), was also calculated. The correlation between those indices and the knee pain score during activities of daily living was investigated. Results: In the right knee, significant correlations were seen between knee extension strength/weight and the scores for knee pain during level ground walking, stair climbing, and sitting on the floor with legs underneath the body (walking, stair climbing p < 0.01, sitting on the floor with legs underneath p < 0.05). In the left knee, significant correlations were seen between knee extension strength/weight and knee pain scores during level ground walking, stair climbing, standing up, and sitting on the floor with legs underneath the body (walking, standing up, sitting on the floor with legs underneath p < 0.01, stair climbing p < 0.05). Knee flexion strength/weight was found to be significantly correlated with knee pain during level ground walking in the right knee (p < 0.05). The correlation with the knee pain score and the difference between extension strength/weight and flexion strength/ weight were significant in all activities in the right knee (walking, stair climbing p < 0.01, others p < 0.05), while in the left knee these values were significant during walking, standing up, and sitting on the floor with legs underneath (standing up p< 0.01, walking, sitting on the floor with legs underneath p
Published: 2014
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50. Decreased bone mass and increased bone turnover with valproate therapy in adults with epilepsy [RETRACTED]

Author: Y. Tomita, K. Takayama, Yoshihiro Sato, H. Motooka, S. Ishida, K. Satoh, H. Maeda, and I. Kondo
Subjects: Adult, Male, medicine.medical_specialty, Osteoporosis, Bone and Bones, Bone resorption, Bone remodeling, chemistry.chemical_compound, N-terminal telopeptide, Bone Density, Internal medicine, medicine, Humans, Bone mineral, Calcium metabolism, Epilepsy, Pyridinoline, business.industry, Valproic Acid, Middle Aged, medicine.disease, Osteopenia, Endocrinology, chemistry, Anticonvulsants, Female, lipids (amino acids, peptides, and proteins), Neurology (clinical), business
Abstract: Background: Bone loss and hypovitaminosis D are reported in patients taking antiepileptic drugs, but little is known about changes in bone and calcium metabolism from valproic acid (VPA).Objective: To assess the relationship of VPA to bone mass and calcium metabolism in 40 adults with epilepsy on long-term VPA monotherapy, 40 age- and sex-matched epileptic patients taking phenytoin (PHT), and 40 healthy control subjects. Bone mineral density (BMD) of the second metacarpal was determined as T- and Z-scores.Results: BMD reduction from control values was 14% (12% in men, 16% in women) with VPA and 13% (12% in men, 15% in women) with PHT. Among patients on VPA, nine (23%) had T-scores below −2.5 SD, suggesting osteoporosis; 15 (37%) had T-scores between −1 and −2.5 SD, suggesting osteopenia. Serum concentrations of calcium were significantly higher with VPA than in PHT or control groups. Serum concentrations of bone Gla protein (a bone formation marker) and pyridinoline cross-linked carboxy-terminal telopeptide of type I collagen (ICTP; a bone resorption marker) associated with either drug significantly exceeded control values. Z-scores for BMD in the VPA group correlated negatively with calcium and ICTP. High ICTP correlated positively with ionized calcium, implying that increased bone resorption caused the latter.Conclusion: Long-term VPA monotherapy can increase bone resorption, leading to decreased BMD.
Published: 2001
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