108 results on '"I El Nakadi"'
Search Results
2. Isolated oesophageal Crohn's disease mimicking oesophageal carcinoma treated by Merendino procedure
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Laurine Verset, Emmanuel Toussaint, C Moschopoulos, Pieter Demetter, I. El Nakadi, S Al Zoghby, and Ali Bohlok
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Endoscopic ultrasound ,medicine.medical_specialty ,Esophageal Neoplasms ,Malignancy ,Esophageal Diseases ,Gastroenterology ,Lesion ,Diagnosis, Differential ,Crohn Disease ,Internal medicine ,Weight Loss ,Medicine ,Humans ,Oesophageal mass ,Aged ,Frozen section procedure ,Crohn's disease ,medicine.diagnostic_test ,business.industry ,General Medicine ,Oesophageal carcinoma ,medicine.disease ,Dysphagia ,Surgery ,Female ,medicine.symptom ,business ,Deglutition Disorders - Abstract
Oesophageal involvement is a very rare presentation of Crohn’s disease. It can occur as an isolated mass causing dysphagia and can be mistaken for malignancy. Here, we report a case of a 75-year-old woman presenting with dysphagia and weight loss. Gastroscopy showed an ulcerating mass, and her barium swallow showed a bird beak appearance at the level of the gastro-oesophageal junction (GEJ). Repetitive biopsies were inconclusive. Fluorodeoxyglucose-positron emission tomography showed high glucose uptake (standardised uptake value: 10.2) at the level of the GEJ. Endoscopic ultrasound classified the lesion as uT3N1. Step-by-step surgical exploration revealed an oesophageal mass. A frozen section examination showed an absence of malignancy and the presence of inflammatory tissue. A partial oesophagogastrostomy was performed, and reconstruction was achieved by a Merendino procedure. Definitive histopathological examination revealed isolated oesophageal Crohn’s disease.
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- 2021
3. Functional outcomes in symptomatic versus asymptomatic patients undergoing incisional hernia repair: Replacing one problem with another? A prospective cohort study in 1312 patients
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E. Benizri, C. Zaranis, S. Manfredelli, A. Bonan, V. Dubuisson, Johan F. Lange, M. Beck, Florent Jurczak, R. Verhaeghe, Antoine Lamblin, E. Abet, H. Khalil, Jacques Soufron, Henry Mercoli, Johannes Jeekel, J.-F. Ain, P. Tiry, M. Isambert, S. Demaret, A. Chau, Gert-Jan Kleinrensink, J.-M. Chollet, C. Largenton, M. Najim, Benjamin Blanc, Yagmur Yurtkap, Yohann Renard, J.-F. Gillion, Dimitri Sneiders, A. Dabrowski, G. Fromont, O. Oberlin, Christophe R. Berney, Christophe Mariette, T. Dugue, A. Bellouard, P. Ortega Deballon, N. Mesli Smain, D. Bilem, J.-M. Thillois, N. Gadiri, Eric Magne, Y. Marion, J.-P. Faure, M. Zeineb, David Moszkowicz, A. Vauchaussade De Chaumont, S. Roos, Jean-Pierre Cossa, P. Vu, Oussama Baraket, Jean-François Gillion, Anand G. Menon, D. Binot, X. Pavis d’Escurac, M. Soler, Jean-Marc Regimbeau, S. Hennequin, V. Pichot Delahaye, Anaelle David, O. Cas, Olivier Glehen, E. Vinatier, Benoit Romain, T. Boukortt, E. Odet, J.B. Putinier, Gijs H J de Smet, P. Frileux, M. Lavy, Laurent Arnalsteen, M. Lepère, O. Brehant, I. El Nakadi, D. Blazquez, A. Champault-Fezais, M. Constantin, N. Le Toux, D. Rouquie, Surgery, and Neurosciences
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Adult ,Male ,medicine.medical_specialty ,Incisional hernia ,medicine.medical_treatment ,030230 surgery ,Asymptomatic ,03 medical and health sciences ,0302 clinical medicine ,Medicine ,Humans ,Incisional Hernia ,Hernia ,Prospective Studies ,Registries ,Prospective cohort study ,Herniorrhaphy ,Aged ,Pain Measurement ,Surgical repair ,Pain, Postoperative ,business.industry ,Incidence (epidemiology) ,Incidence ,Postoperative complication ,General Medicine ,Middle Aged ,Surgical Mesh ,medicine.disease ,Hernia repair ,Surgery ,Treatment Outcome ,030220 oncology & carcinogenesis ,Female ,medicine.symptom ,business - Abstract
Background: Incisional hernias can be associated with pain or discomfort. Surgical repair especially mesh reinforcement, may likewise induce pain. The primary objective was to assess the incidence of pain after hernia repair in patients with and without pre-operative pain or discomfort. The secondary objectives were to determine the preferred mesh type, mesh location and surgical technique in minimizing postoperative pain or discomfort. Materials and methods: A registry-based prospective cohort study was performed, including patients undergoing incisional hernia repair between September 2011 and May 2019. Patients with a minimum follow-up of 3–6 months were included. The incidence of hernia related pain and discomfort was recorded perioperatively. Results: A total of 1312 patients were included. Pre-operatively, 1091 (83%) patients reported pain or discomfort. After hernia repair, 961 (73%) patients did not report pain or discomfort (mean follow-up = 11.1 months). Of the pre-operative asymptomatic patients (n = 221), 44 (20%, moderate or severe pain: n = 14, 32%) reported pain or discomfort after mean follow-up of 10.5 months. Of those patients initially reporting pain or discomfort (n = 1091), 307 (28%, moderate or severe pain: n = 80, 26%) still reported pain or discomfort after a mean follow-up of 11.3 months postoperatively. Conclusion: In symptomatic incisional hernia patients, hernia related complaints may be resolved in the majority of cases undergoing surgical repair. In asymptomatic incisional hernia patients, pain or discomfort may be induced in a considerable number of patients due to surgical repair and one should be aware if this postoperative complication.
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- 2020
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4. Pristine Visibility Associated to the use of Texture and Colour Enhancement Imaging (TXI) During Submucosal Dissection: A Case of Large Barrett’s Neoplasia
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I. El Nakadi, Arnaud Lemmers, J-L. van Laethem, AM Bucalau, Laurine Verset, and Jacques Devière
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business.industry ,Visibility (geometry) ,Computer vision ,Artificial intelligence ,Submucosal dissection ,business ,Texture (geology) ,Geology - Published
- 2021
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5. Serum C-reactive protein concentration on post-operative day2-4 predicts post-operative complications after cyto-reductive surgery and hyper-thermic intraperitoneal chemotherapy
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M. Benavides Villar, Ali Bohlok, Fikri Bouazza, I. El Nakadi, G. Machiels, A. Hendlisz, Michel Moreau, Gabriel Liberale, Vincent Donckier, and A. Deleporte
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medicine.medical_specialty ,Oncology ,biology ,business.industry ,C-reactive protein ,medicine ,biology.protein ,Surgery ,Intraperitoneal chemotherapy ,General Medicine ,Post operative ,business - Published
- 2019
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6. Low anterior resection syndrome after surgical treatment of rectal cancer: Associated factors and correlation with the quality of life
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Fikri Bouazza, A. Hendlisz, Ali Bohlok, C. Mercier, Vincent Donckier, Luigi Moretti, I. El Nakadi, M. Gomez Galdon, and Gabriel Liberale
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medicine.medical_specialty ,Low Anterior Resection ,Oncology ,Colorectal cancer ,business.industry ,medicine ,Surgery ,General Medicine ,medicine.disease ,Surgical treatment ,business - Published
- 2019
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7. Multicentre study of neoadjuvant chemotherapy for stage I and II oesophageal cancer
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S Bekkar, C Gronnier, F Renaud, A Duhamel, A Pasquer, J Théreaux, J Gagnière, B Meunier, D Collet, C Mariette, A Dhahri, D Lignier, C Cossé, J-M Regimbeau, G Luc, M Cabau, J Jougon, B Badic, P Lozach, J P Bail, S Cappeliez, I El Nakadi, G Lebreton, A Alves, R Flamein, D Pezet, F Pipitone, B Stan-Iuga, N Contival, E Pappalardo, X Coueffe, S Msika, S Mantziari, N Demartines, F Hec, M Vanderbeken, W Tessier, N Briez, F Fredon, A Gainant, M Mathonnet, J M Bigourdan, S Mezoughi, C Ducerf, J Baulieux, J-Y Mabrut, O Baraket, G Poncet, M Adam, D Vaudoyer, P Jourdan Enfer, L Villeneuve, O Glehen, T Coste, J-M Fabre, F Marchal, R Frisoni, A Ayav, L Brunaud, L Bresler, C Cohen, O Aze, N Venissac, D Pop, J Mouroux, I Donici, M Prudhomme, E Felli, S Lisunfui, M Seman, G Godiris Petit, M Karoui, C Tresallet, F Ménégaux, J-C Vaillant, L Hannoun, B Malgras, D Lantuas, K Pautrat, M Pocard, P Valleur, J H Lefevre, N Chafai, P Balladur, M Lefrançois, Y Parc, F Paye, E Tiret, M Nedelcu, L Laface, T Perniceni, B Gayet, K Turner, A Filipello, J Porcheron, O Tiffet, N Kamlet, R Chemaly, A Klipfel, P Pessaux, C Brigand, S Rohr, N Carrère, C Da Re, F Dumont, D Goéré, D Elias, C Bertrand, Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U837 (JPArc), Université Lille Nord de France (COMUE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Service de Chirurgie Hépatobiliaire et Digestive [Rennes] = Hepatobiliary and Digestive Surgery [Rennes], CHU Pontchaillou [Rennes], and Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U1172 Inserm - U837 (JPArc)
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Male ,medicine.medical_specialty ,Esophageal Neoplasms ,medicine.medical_treatment ,[SDV]Life Sciences [q-bio] ,Population ,Adenocarcinoma ,Disease-Free Survival ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Antineoplastic Combined Chemotherapy Protocols ,medicine ,Humans ,030212 general & internal medicine ,Hospital Mortality ,education ,Neoadjuvant therapy ,Chemotherapy ,education.field_of_study ,business.industry ,Mortality rate ,Hazard ratio ,Case-control study ,Cancer ,Middle Aged ,medicine.disease ,Neoadjuvant Therapy ,3. Good health ,Surgery ,Europe ,Chemotherapy, Adjuvant ,030220 oncology & carcinogenesis ,Case-Control Studies ,Propensity score matching ,Carcinoma, Squamous Cell ,Female ,Neoplasm Recurrence, Local ,business - Abstract
Background The benefit of neoadjuvant chemotherapy (NCT) for early-stage oesophageal cancer is unknown. The aim of this study was to assess whether NCT improves the outcome of patients with stage I or II disease. Methods Data were collected from 30 European centres from 2000 to 2010. Patients who received NCT for stage I or II oesophageal cancer were compared with patients who underwent primary surgery with regard to postoperative morbidity, mortality, and overall and disease-free survival. Propensity score matching was used to adjust for differences in baseline characteristics. Results Of 1173 patients recruited (181 NCT, 992 primary surgery), 651 (55·5 per cent) had clinical stage I disease and 522 (44·5 per cent) had stage II disease. Comparisons of the NCT and primary surgery groups in the matched population (181 patients in each group) revealed in-hospital mortality rates of 4·4 and 5·5 per cent respectively (P = 0·660), R0 resection rates of 91·7 and 86·7 per cent (P = 0·338), 5-year overall survival rates of 47·7 and 38·6 per cent (hazard ratio (HR) 0·68, 95 per cent c.i. 0·49 to 0·93; P = 0·016), and 5-year disease-free survival rates of 44·9 and 36·1 per cent (HR 0·68, 0·50 to 0·93; P = 0·017). Conclusion NCT was associated with better overall and disease-free survival in patients with stage I or II oesophageal cancer, without increasing postoperative morbidity.
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- 2016
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8. Increased Nerve Density in Deep Infiltrating Endometriotic Nodules
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V. De Moor, Charles Chapron, Vincent Anaf, Jean Christophe Noël, G. Pistofidis, and I. El Nakadi
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Pathology ,medicine.medical_specialty ,Neurofilament ,business.industry ,Vaginal Diseases ,Endometriosis ,Obstetrics and Gynecology ,Nodule (medicine) ,macromolecular substances ,medicine.disease ,Deep infiltrating endometriosis ,Reproductive Medicine ,Neurofilament Proteins ,Vagina ,Neuropathic pain ,medicine ,Humans ,Female ,Prospective Studies ,Nerve Tissue ,medicine.symptom ,business - Abstract
Background/Aims: Deep infiltrating endometriosis is a very painful condition and the mechanism of pain is still poorly understood. Pain and hyperalgesia can partly be explained by an increased number of nerve structures in the painful lesion. In order to clarify this issue, we assessed the nerve density in deep infiltrating endometriotic nodules of the posterior vagina and in the adjacent healthy vaginal tissue of the same patient. Methods: A prospective clinical and pathological study of 31 cases of deep infiltrating vaginal endometriotic nodules was conducted. Fifteen patients were in the proliferative phase and 16 in the secretory phase. The nerve density was studied by immunohistochemistry with the monoclonal antibody NF against neurofilaments in deep infiltrating endometriosis and in the adjacent unaffected vaginal tissue in the proliferative and in the secretory phases. Neurofilaments constitute the main structural elements of neuronal axons and dendrites. Results: The nerve density was significantly different in the endometriotic nodule than in the adjacent unaffected vaginal tissue (p = 0.0013). The same significant difference was found between endometriotic nodules and the unaffected vagina in the proliferative phase (p = 0.009) and in the secretory phase (p = 0.04). This difference was not significant between the proliferative and the secretory phases in the endometriotic lesions and in the controls. Conclusions: We hypothesize that the significantly increased number of nerve structures in the endometriotic nodules may contribute to the occurrence of severe and neuropathic pain that characterizes these lesions
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- 2010
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9. Small cell carcinoma of the esophagus: a multicentre Rare Cancer Network study
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J.-L. Van Laethem, K Khanfir, T Rozema, P. Van Houtte, I. El Nakadi, D C Weber, Alain Hendlisz, Bertrand Vos, and Robert C. Miller
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medicine.medical_specialty ,business.industry ,Gastroenterology ,Cancer ,Retrospective cohort study ,General Medicine ,medicine.disease ,Small-cell carcinoma ,Chemotherapy regimen ,Dysphagia ,Surgery ,medicine.anatomical_structure ,Interquartile range ,Epidemiology ,Medicine ,Esophagus ,medicine.symptom ,business - Abstract
Small cell carcinoma of the esophagus (SCCE) is a rare and aggressive malignant tumor with a poor prognosis. The aims of this retrospective study were to analyze the epidemiology, clinical characteristics, and treatment outcomes of these patients. Between 1994 and 2004, 24 patients with SCCE from several centers were reviewed for data on demographics, presenting symptoms, diagnosis, disease stage, type of treatment, and outcome. SCCE occurs in the sixth decade: median age (interquartile range [IQR]): 65 (59-69) years with a male predominance (63%). The most common complaining symptoms were rapidly progressive dysphagia (79%), weight loss (54%), and retrosternal/epigastric pain (46%). The tumor arises primarily in the middle (52%) or in the lower (35%) third of the esophagus. History of tobacco and alcohol exposure was present in 90% and 70% of case, respectively. Extensive disease was present in 13 cases (54%) at initial diagnosis. The overall median survival (IQR) was 11 (8-20) months for all 24 patients, and the 2-year overall survival was 25.1%. Four patients were alive more than 2 years after treatment. Chemotherapy increased the survival compared with symptomatic management in extensive disease (median survival [IQR]: 9.5 [6-14] vs. 6 [4-7] months, P= 0.05). In limited disease, concurrent chemo-radiotherapy was more effective than non-concurrent treatment (median survival [IQR]: 36 [14-93] vs. 11 [9-15] months, P= 0.04). Two patients were treated by surgery and chemoradiation therapy with a survival of 35 and 66 months. Chemotherapy is the cornerstone of treatment of SCCE in all stage. For limited disease SCCE, concurrent chemo-radiotherapy is the primary choice compared with sequential approach. The role of surgery was not assessable in our study.
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- 2010
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10. How Should we Treat Mucinous Appendiceal Neoplasm ? By Laparoscopy or Laparotomy ?: A Case Report
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F. de Neubourg, N. Sirtaine, I. El Nakadi, D. Noterman, Ph. Lemaitre, Gabriel Liberale, and C. Moerman
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Laparoscopic surgery ,medicine.medical_specialty ,medicine.medical_treatment ,Mucocele ,Appendix ,Cystadenoma, Mucinous ,Laparotomy ,medicine ,Cecal Diseases ,Humans ,Pseudomyxoma peritonei ,Cyst ,Laparoscopy ,Mucinous cystadenoma ,Aged ,Incidental Findings ,medicine.diagnostic_test ,business.industry ,General surgery ,General Medicine ,medicine.disease ,medicine.anatomical_structure ,Appendiceal Neoplasms ,Cystadenoma ,Female ,Surgery ,business - Abstract
Appendicular mucocele (AM) usually denotes a dilatation of the appendiceal lumen as a result of mucus accumulation that may be related to various neoplastic and non-neoplastic processes. Most of them are discovered incidentally. Treatment consists in complete resection avoiding rupture of the cyst in the peritoneal cavity. Indeed, rupture of such a cystic lesion in the peritoneal cavity can induce a catastrophic complication such as 'pseudomyxoma peritonei' (PMP). Therefore, some authors recommend an open surgical treatment. Currently, the debate concerning the best surgical technique to adopt for AM remains controversial. We report a case of AM found incidentally and treated by laparoscopy. The macroscopic aspect of the appendix suggested the diagnosis intra-operatively and every effort was made to avoid cystic rupture during appendicular resection. The histopathological diagnosis was mucinous cystadenoma. The patient is doing well at 2-year follow-up. The reported case and literature review show us that AM is not a contra-indication for laparoscopic surgery, but major concern resides in the early recognition of such a lesion at laparoscopy and in taking appropriate precautionary measures to avoid rupture in the peritoneal cavity.
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- 2010
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11. Nissen versus Toupet fundoplication: Results of a randomized and multicenter trial
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Abdel Ilah Mehdi, Vaneukem P, Jean-Jacques Houben, Michel Gelin, K. Bétroune, I. El Nakadi, Jean Closset, E. Guérin, and J. C. Lefèbvre
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Male ,medicine.medical_specialty ,Fundoplication ,Postoperative Hemorrhage ,Gastroenterology ,law.invention ,Patient satisfaction ,Randomized controlled trial ,law ,Internal medicine ,Multicenter trial ,Eructation ,medicine ,Flatulence ,Humans ,Laparoscopy ,medicine.diagnostic_test ,business.industry ,Esophageal disease ,Reflux ,Pneumothorax ,medicine.disease ,Surgery ,Endoscopy ,Treatment Outcome ,Patient Satisfaction ,Gastroesophageal Reflux ,Female ,Deglutition Disorders ,business ,Follow-Up Studies ,Abdominal surgery - Abstract
Laparoscopic Toupet fundoplication (TF) is reported to be as effective as Nissen (NF), but to be associated with fewer unfavorable postoperative side-effects. This study evaluates the one- and three-year clinical outcome of 140 randomized patients after a laparoscopic NF or TF. Inclusion criteria included patients over 16 years old with complications of gastro-oesophageal reflux disease (GORD) and persistence or recurrence of symptoms after three months of treatment. Subjects with a previous history of gastric surgery or repeated fundoplication, brachy-oesophagus or severe abnormal manometry results were excluded. Seventy-seven NF and 63 TF were performed. The severity of symptoms was assessed before and after the procedure. One hundred and twenty-one of the 140 patients after one year, and 118 after three years, were evaluated and no statistically significant clinical difference was observed. The level of satisfaction concerning the outcome of the operation remained high after one or three years regardless of the type of fundoplication performed. Functional complications after NF are not avoided with TF.
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- 2007
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12. Newly Developed Barrett’s Esophagus after Subtotal Esophagectomy
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C. Brasseur, Denis Franchimont, I. El-Nakadi, A. Covas, J. Devière, and J.-L. Van Laethem
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Male ,medicine.medical_specialty ,Esophageal Neoplasms ,medicine.medical_treatment ,Adenocarcinoma ,Gastroenterology ,Barrett Esophagus ,Internal medicine ,medicine ,Humans ,Esophagus ,Aged ,Retrospective Studies ,business.industry ,Esophageal disease ,Reflux ,Intestinal metaplasia ,Proton Pump Inhibitors ,Middle Aged ,medicine.disease ,Surgery ,Esophagectomy ,medicine.anatomical_structure ,Chemotherapy, Adjuvant ,Barrett's esophagus ,Carcinoma, Squamous Cell ,Female ,business ,Complication ,Esophagitis - Abstract
BACKGROUND AND STUDY AIMS: More detailed information regarding the early mucosal events that lead to intestinal metaplasia would be very beneficial for understanding the pathogenesis of Barrett's esophagus (BE). Gastroesophageal reflux and duodenogastroesophageal reflux play a major role in the pathogenesis of Barrett's esophagus. The aim of this study was to investigate the prevalence of newly developed BE in patients who had previously undergone a subtotal esophagectomy - a clinical condition characterized by the absence of a lower esophageal sphincter and massive gastroesophageal reflux. PATIENTS AND METHODS: A retrospective examination was carried out on all patients who underwent subtotal esophagectomy (n = 87) listed in our institution's computer files from 1995 to 2000. Twenty-one patients were excluded due to missing data or no upper gastrointestinal endoscopy after surgery. RESULTS: Based on the Savary-Miller classification, 47 patients developed either type I (n = 2), II (n = 8), III (n = 11) or IV (n = 26) esophagitis after surgery. Newly developed BE was observed in nine patients (13.5 %) after subtotal esophagectomy (median time to diagnosis: 489 days, range 43 - 1172). None of the patients had persistent BE immediately after surgery, and two of the patients with newly developed BE had had no history of BE before surgery or at the time of surgery. Proton-pump inhibitor therapy after surgery and neoadjuvant chemotherapy did not appear to influence the development of BE after subtotal esophagectomy. CONCLUSIONS: Newly developed BE after subtotal esophagectomy may provide further insights into the early mucosal events that lead to intestinal metaplasia and into the roles of gastroesophageal and duodenoesophageal reflux in the pathogenesis of BE.
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- 2003
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13. Intraperitoneal follicular dendritic cell sarcoma: Role of chemotherapy and bone marrow allotransplantation in locally advanced disease?
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N. de Saint Aubain, I. El Nakadi, K. Keriakos, Marie-Agnès Azerad, and Gabriel Liberale
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Pathology ,medicine.medical_specialty ,bone marrow allotransplantation ,Follicular dendritic cell sarcoma (FDCS) ,medicine.medical_treatment ,Case Report ,Disease ,Bone marrow allotransplantation ,intraperitoneal ,chemotherapy ,lcsh:RC254-282 ,medicine ,Chemotherapy ,Intraperitoneal ,Antigen-presenting cell ,follicular dendritic cell sarcoma (FDCS) ,business.industry ,Cancer ,medicine.disease ,lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,Cancérologie ,medicine.anatomical_structure ,Oncology ,Follicular dendritic cell sarcoma ,Bone marrow ,business ,Biomedical engineering ,Rare disease ,Allotransplantation - Abstract
We describe a case of a 44 year-old woman diagnosed with follicular dendritic cell sarcoma (FDCS). FDCS is a very rare disease affecting the dendritic antigen presenting cells and is often misdiagnosed. Surgery is considered the best treatment modality, followed by chemotherapy. In our case, surgical excision was not possible, therefore the patient received two lines of chemotherapy followed by bone marrow allotransplantation, then a third line of chemotherapy with a complete metabolic response seen on PET/computed tomography (CT) follow-up 29 months later. A review of the literature has been performed., SCOPUS: ar.j, info:eu-repo/semantics/published
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- 2015
14. Prospective evaluation of the impact of multidisciplinary meetings on the decision making process in gastro-intestinal oncology
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A. Hendlisz, Gabriel Liberale, Michel Moreau, A. Daher, M. Gomez Galdon, Luigi Moretti, Vincent Donckier, I. El Nakadi, D. De Becker, and Patrick Flamen
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Cancer Research ,medicine.medical_specialty ,Oncology ,Multidisciplinary approach ,business.industry ,medicine ,Decision-making ,Intensive care medicine ,business ,Prospective evaluation ,Gastro intestinal - Published
- 2017
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15. Near infrared fluorescence imaging after intraoperative injection of indocyanine green to improve the staging during cytoreductive surgery for peritoneal carcinomatosis of colorectal origin: results of a pilot prospective study (NCT02032485)
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I. El Nakadi, B. Ahmed, M. Gomez Galdon, Vincent Donckier, Sophie Vankerckhove, Denis Larsimont, Pierre Bourgeois, and Gabriel Liberale
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Cancer Research ,medicine.medical_specialty ,Near-Infrared Fluorescence Imaging ,business.industry ,Peritoneal carcinomatosis ,Surgery ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Oncology ,chemistry ,030220 oncology & carcinogenesis ,Medicine ,030211 gastroenterology & hepatology ,Radiology ,business ,Prospective cohort study ,Cytoreductive surgery ,Indocyanine green - Published
- 2017
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16. Laparoscopically assisted segmental sigmoid resection (LASSR) for sigmoid endometriosis
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Vincent Anaf, N. Sperduto, I. El Nakadi, P. Simon, and J.-C. Noel
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medicine.medical_specialty ,business.industry ,Endometriosis ,Obstetrics and Gynecology ,Medicine (miscellaneous) ,Cosmesis ,Rectum ,Anastomosis ,medicine.disease ,Extracorporeal ,Surgery ,Dissection ,medicine.anatomical_structure ,Paracolic gutters ,medicine ,Adenomyosis ,business - Abstract
Objectives To confirm the feasibility and safety of laparoscopically assisted segmental sigmoid resection (LASSR) for sigmoid endometriosis. Setting Gynaecology and surgery departments at a university hospital. Subjects Between August 1997 and April 1999, five patients with symptomatic sigmoid endometriosis and concomitant pelvic endometriosis underwent LASSR. During that same period laparoscopic procedures for endometriosis involving the intestinal tract included: five anterior resections of the rectum with transanal end-to-end anastomosis for extensive rectosigmoid endometriosis, 26 resections of rectovaginal endometriotic nodules and one appendectomy. Interventions These included: laparoscopic dissection of the left large bowel from its adherent neighbouring structures, incision of the lateral and medial peritoneal reflections of the mesosigmoid, incision of the left paracolic gutter, identification of the left ovarian vessels and left ureter, extracorporeal resection of the sigmoid and lateroterminal handsewn anastomosis, and laparoscopic treatment of concomitant pelvic endometriosis. Results Neither intra- nor postoperative complications occurred. The mean operating time was 210 min. Postoperative ileus lasted less than 72 h in all cases (n = 5). The mean postoperative hospital stay was 6 days. There was no recurrence of sigmoid endometriosis symptoms over follow up for a mean of 15.2 months. Conclusions LASSR is a feasible and safe technique which is indicated for symptomatic sigmoid endometriosis. It allows the simultaneous laparoscopic management of pelvic endometriosis. Better cosmesis is an immediately recognizable benefit of this technique. Reduced postoperative pain and shortened postoperative ileus represent presumed advantages of LASSR compared with open surgery. The use of LASSR can help to reduce the cost of the laparoscopic instrumentation that is necessary for total laparoscopic colectomy.
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- 2000
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17. Laparoscopic Nissen fundoplication after failure of Enteryx injection into the lower esophageal sphincter
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Marc Zalcman, Jacques Devière, Jean Closset, Emmanuel Coppens, I. El Nakadi, Michel Gelin, and V. De Moor
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Adult ,Male ,Laparoscopic surgery ,medicine.medical_specialty ,medicine.medical_treatment ,Fundoplication ,Injections, Intralesional ,Nissen fundoplication ,medicine ,Humans ,Esophagus ,Laparoscopy ,Aged ,medicine.diagnostic_test ,business.industry ,Esophageal disease ,Middle Aged ,medicine.disease ,digestive system diseases ,Surgery ,Endoscopy ,medicine.anatomical_structure ,Gastroesophageal Reflux ,GERD ,Female ,Polyvinyls ,Esophagogastric Junction ,business ,Abdominal surgery - Abstract
We investigated the feasibility, safety, and efficacy of laparoscopic antireflux surgery (LARS) after failure of Enteryx injection in the lower esophageal sphincter for the treatment of gastroesophageal reflux disease (GERD). Four patients underwent LARS after failure of Enteryx injection. Particular care was taken during the procedure to identify unusual material or fibrosis. All patients underwent LARS successfully. In three patients, tight adhesions with fibrous tissues and black foreign material were observed around the esophagus. No complications occurred during the procedures. The postoperative period was uneventful and functional results were excellent. LARS following Enteryx injection is feasible. Careful dissection is mandatory to avoid operative complications. Both techniques may be considered as options for treating GERD.
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- 2004
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18. Small cell carcinoma of the esophagus: a multicentre Rare Cancer Network study
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Bertrand, Vos, T, Rozema, R C, Miller, A, Hendlisz, J L, Van Laethem, K, Khanfir, D C, Weber, I, El Nakadi, and P, Van Houtte
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Male ,Treatment Outcome ,Esophageal Neoplasms ,Antineoplastic Combined Chemotherapy Protocols ,Humans ,Female ,Carcinoma, Small Cell ,Middle Aged ,Combined Modality Therapy ,Survival Analysis ,Aged ,Retrospective Studies - Abstract
Small cell carcinoma of the esophagus (SCCE) is a rare and aggressive malignant tumor with a poor prognosis. The aims of this retrospective study were to analyze the epidemiology, clinical characteristics, and treatment outcomes of these patients. Between 1994 and 2004, 24 patients with SCCE from several centers were reviewed for data on demographics, presenting symptoms, diagnosis, disease stage, type of treatment, and outcome. SCCE occurs in the sixth decade: median age (interquartile range [IQR]): 65 (59-69) years with a male predominance (63%). The most common complaining symptoms were rapidly progressive dysphagia (79%), weight loss (54%), and retrosternal/epigastric pain (46%). The tumor arises primarily in the middle (52%) or in the lower (35%) third of the esophagus. History of tobacco and alcohol exposure was present in 90% and 70% of case, respectively. Extensive disease was present in 13 cases (54%) at initial diagnosis. The overall median survival (IQR) was 11 (8-20) months for all 24 patients, and the 2-year overall survival was 25.1%. Four patients were alive more than 2 years after treatment. Chemotherapy increased the survival compared with symptomatic management in extensive disease (median survival [IQR]: 9.5 [6-14] vs. 6 [4-7] months, P= 0.05). In limited disease, concurrent chemo-radiotherapy was more effective than non-concurrent treatment (median survival [IQR]: 36 [14-93] vs. 11 [9-15] months, P= 0.04). Two patients were treated by surgery and chemoradiation therapy with a survival of 35 and 66 months. Chemotherapy is the cornerstone of treatment of SCCE in all stage. For limited disease SCCE, concurrent chemo-radiotherapy is the primary choice compared with sequential approach. The role of surgery was not assessable in our study.
- Published
- 2010
19. Classification of primary and incisional abdominal wall hernias
- Author
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A. Hoeferlin, Filip Muysoms, Tim Tollens, Ulrich A. Dietz, Maarten Simons, Giampiero Campanelli, Marc Miserez, Uwe Klinge, Gérard Champault, T. Vierendeels, P. Hauters, E. Chelala, I. El Nakadi, R. K. J. Simmermacher, Maciej Śmietański, Agneta Montgomery, C. Sommeling, Frederik Berrevoet, Hasan H. Eker, Andrew N. Kingsnorth, and M. Hidalgo Pascual
- Subjects
Male ,Postoperative Complications -- epidemiology ,medicine.medical_specialty ,Future studies ,Epigastric hernia ,Incisional hernia ,Umbilical hernia ,Abdominal wall hernia ,Classification ,Ventral hernia ,Surgery ,Severity of Illness Index ,Abdominal wall ,Postoperative Complications ,Recurrence ,Hernia, Ventral -- classification -- surgery ,medicine ,Hernia, Umbilical -- classification -- surgery ,Humans ,Hernia ,Hernia, Abdominal -- classification -- surgery ,business.industry ,General surgery ,Surgical Mesh ,Prognosis ,medicine.disease ,Hernia, Ventral ,digestive system diseases ,Hernia, Abdominal ,Cancérologie ,Surgical Procedures, Operative -- adverse effects -- methods ,stomatognathic diseases ,Treatment Outcome ,surgical procedures, operative ,medicine.anatomical_structure ,Surgical mesh ,Surgical Procedures, Operative ,Original Article ,Female ,business ,Hernia, Umbilical ,Abdominal surgery - Abstract
A classification for primary and incisional abdominal wall hernias is needed to allow comparison of publications and future studies on these hernias. It is important to know whether the populations described in different studies are comparable., Comparative Study, Consensus Development Conference, Journal Article, Review, SCOPUS: ar.j, info:eu-repo/semantics/published
- Published
- 2009
20. Actinomycotic abscess of the anterior abdominal wall: a case report and literature review
- Author
-
Michel Gelin, D Pitot, Pieter Demetter, I. El Nakadi, V. De Moor, and S Place
- Subjects
Surgical resection ,medicine.medical_specialty ,Actinomycosis ,Abdominal wall ,Diagnosis, Differential ,Abdominal actinomycosis ,X ray computed ,medicine ,Actinomyces ,Humans ,Abscess ,Laparotomy ,biology ,business.industry ,General Medicine ,Middle Aged ,medicine.disease ,Actinomyces israelii ,biology.organism_classification ,Surgery ,stomatognathic diseases ,medicine.anatomical_structure ,Female ,business ,Tomography, X-Ray Computed - Abstract
Actinomycosis is a rare, chronic, suppurative, pseudotumoral illness caused by an anaerobic gram positive organism usually Actinomyces israelii which can mimick a tumoral pathology leading to a mutilating surgical resection. We report a case of abdominal actinomycosis and a literature review.
- Published
- 2008
21. Recommendations for general surgeons facing incidental peritoneal carcinomatosis of colorectal origin
- Author
-
I. El Nakadi, Gabriel Liberale, M. Van Den Eynde, and Alain Hendlisz
- Subjects
medicine.medical_specialty ,Colorectal cancer ,business.industry ,General surgery ,Decision Making ,Intraperitoneal chemotherapy ,General Medicine ,Hyperthermia, Induced ,medicine.disease ,Combined Modality Therapy ,Peritoneal carcinomatosis ,Oncology ,Chemotherapy, Cancer, Regional Perfusion ,medicine ,Humans ,Surgery ,business ,Colorectal Neoplasms ,Peritoneal Neoplasms - Published
- 2007
22. Amelanotic malignant melanoma of the esophagus. Report of a case
- Author
-
P, De Simone, M, Gelin, and I, El Nakadi
- Subjects
Neoplasms, Multiple Primary ,Fatal Outcome ,Esophageal Neoplasms ,Carcinoma, Squamous Cell ,Humans ,Female ,Middle Aged ,Epiglottis ,Laryngeal Neoplasms ,Melanoma - Abstract
Primary malignant melanomas of the esophagus are rare neoplasms with aggressive behavior and tendency to lymphatic and hematogenous spread. We report on a patient affected with a primary amelanotic melanoma of the esophagus synchronous to a squamous cell carcinoma of the epiglottis and treated by subtotal esophagectomy. A 58-year-old woman presented with a three-month history of dysphagia, retrosternal pain and weight loss. An upper gastrointestinal endoscopy revealed a 3 cm, non pigmented, polypoid mass of the middle esophagus and biopsy was consistent with undifferentiated carcinoma. Fiberoptic bronchoscopy revealed a 0.5 cm, polypoid lesion of the right aspect of the epiglottis consistent with a squamous cell carcinoma. The esophageal neoplasm was treated by subtotal esophagectomy while the squamous cell carcinoma of the epiglottis was referred to radiotherapy 1 month after surgery. Microscopy showed diffuse proliferation of anaplastic cells with multiple mitotic figures, marked nuclei and multilobulated nucleoli. The neoplasm stained positive for HBM-45 antigen and S-100 protein. Tumor stage was pT1N0M0. Review of patient's medical history and exploration of skin and mucous membranes failed to reveal malignant lesions and definitive diagnosis was primary amelanotic malignant melanoma of the esophagus. The patient died 16 months after surgery of disseminated disease. In conclusion the present case confirms that primary malignant melanomas of the esophagus have a dismal outcome even in cases of early-stage lesions amenable to surgical resection.
- Published
- 2006
23. Oesophageal perforation by an anterior cervical fixation device: management in debilitated patients
- Author
-
V, De Moor, O, De Witte, M, Zalcman, M, Gelin, O, Le Moine, and I, El Nakadi
- Subjects
Male ,Esophageal Perforation ,Middle Aged ,Risk Assessment ,Severity of Illness Index ,Radiography ,Fracture Fixation, Internal ,Treatment Outcome ,Foreign-Body Migration ,Gastroscopy ,Cervical Vertebrae ,Humans ,Spinal Fractures ,Female ,Laparoscopy ,Esophagoscopy ,Bone Plates ,Follow-Up Studies - Abstract
Oesophageal perforation following anterior cervical fixation has been reported in the neurosurgical and orthopaedic literature as a rare complication of such procedure. The complications associated with oesophageal perforation may range from minor symptoms to mediastinitis and death. We report two oesophageal perforations following cervical fixation device migration in patients with poor prognosis, managed successfully with conservative surgical and endoscopic techniques.
- Published
- 2005
24. Idiopathic eosinophilic oesophagitis: atypical presentation of a rare disease
- Author
-
S, Evrard, H, Louis, M, Kahaleh, M, Zalcman, N, Nagy, I, El Nakadi, and J, Devière
- Subjects
Diagnosis, Differential ,Esophagectomy ,Male ,Treatment Outcome ,Esophageal Neoplasms ,Eosinophilia ,Esophagitis ,Humans ,Aged - Abstract
A 72 year-old man presented severe dysphagia and weight loss of recent onset. Repeated oesophageal endoscopy and biopsies with macroforceps were normal. Oesophageal manometry disclosed features compatible with achalasia. Oesophageal EUS endoscopy localized an infiltrating process between muscular layers of the oesophageal wall and CT scan delimited a circular thickening in the inferior part of the oesophagus. Because of severe clinical presentation mimicking a possible oesophageal neoplasm like a lymphoma, partial oesophagectomy was performed and revealed eosinophilic oesophagitis. This unusual presentation emphasizes that idiopathic eosinophilic oesophagitis must be proposed in the differential diagnosis of dysphagia, even in old patient without apparent oesophageal lesion at endoscopy.
- Published
- 2004
25. [The surgical gastroenterology department]
- Author
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M, Gelin, J, Closset, V, Donckier, I, el Nakadi, and J, Van de Stadt
- Subjects
Hospitals, University ,Biomedical Research ,Belgium ,Gastrointestinal Diseases ,Gastroenterology ,Humans ,Surgery Department, Hospital ,Digestive System Surgical Procedures - Abstract
The Department of Digestive Surgery was born in 1977. It is a part of the medical surgical unit of gastroenterology and hepatopancreatology. The various developed sectors concern hepatic surgery and liver transplantation (treatment of hepatic tumors and cirrhosis), pancreatic surgery and surgery of the biliary tract (treatment of benign and malignant pancreatic tumors, tumor of the biliary tract, chronic pancreatitis and biliary stones), surgery of morbid obesity (gastroplasty or gastric by-pass), surgery of the upper digestive tract (benign and malignant tumors of the oesophagus or the stomach, treatment of gastroesophageal reflux), surgery of the abdominal wall, colorectal surgery and surgery of the inflammatory bowel diseases (colorectal cancer, familial polyposis, Crohn's disease, ulcerative colitis), proctologic surgery and surgery of anorectal functional disorders, neonatal and paediatric surgery.
- Published
- 2003
26. Minimally invasive approach to Boerhaave's syndrome: a pilot study of three cases
- Author
-
I. El Nakadi and S. Landen
- Subjects
Male ,medicine.medical_specialty ,Boerhaave syndrome ,medicine.medical_treatment ,Pilot Projects ,Esophageal Diseases ,Esophagus ,Esophageal stent ,medicine ,Thoracoscopy ,Humans ,Minimally Invasive Surgical Procedures ,Endoscopic stenting ,Thoracotomy ,Esophageal Fistula ,Aged ,medicine.diagnostic_test ,Mediastinoscope ,Rupture, Spontaneous ,Esophageal disease ,business.industry ,General surgery ,Endoscopy ,Syndrome ,Middle Aged ,medicine.disease ,Surgery ,Laparoscopy ,Stents ,business - Abstract
Background: Boerhaave's syndrome requires urgent thoracotomy, laparotomy, or both for esophageal repair and pleuromediastinal debridement. Minimally invasive techniques may be suitable alternatives. Material and methods: Over a period of 12 months, three patients with spontaneous esophageal perforations after forceful vomiting were treated by a combination of minimally invasive techniques including laparoscopy, thoracoscopy, mediastinoscopy, and endoscopic stenting. Results: Esophageal repair was performed transhiatally via laparoscopy using primary suture, primary suture reinforced by a fundic patch, and fundic patch alone in one patient each. One patient had a second perforation of the proximal esophagus, which was sutured through a cervical incision. This patient successfully underwent secondary endoscopic stenting for a persistent esophageal fistula. Mediastinal debridement was performed transhiatally and also by means of a mediastinoscope introduced via the cervical incision in one patient. One patient required secondary thoracoscopic debridement of a pleural empyema but died of sepsis after 1 month. The two other patients recovered and were discharged from the hospital after 2 and 8 weeks, respectively. Conlusions: Boerhaave's syndrome is amenable to minimally invasive techniques. Avoidance of a formal thoracotomy with its resulting morbidity could be of considerable benefit to these critically ill patients.
- Published
- 2001
27. Relationship between endometriotic foci and nerves in rectovaginal endometriotic nodules
- Author
-
Isabelle Fayt, P. Simon, Vincent Anaf, Th. Simonart, Marie-Odile Peny, Jean Christophe Noël, Frédéric Buxant, and I. El Nakadi
- Subjects
Adult ,Pathology ,medicine.medical_specialty ,Endometriosis ,Uterus ,Pelvic Pain ,Masson's trichrome stain ,Lesion ,Endometrium ,Dysmenorrhea ,medicine ,Humans ,Pelvis ,Pain, Postoperative ,business.industry ,Pelvic pain ,Rehabilitation ,Obstetrics and Gynecology ,Nodule (medicine) ,Anatomy ,medicine.disease ,Fibrosis ,medicine.anatomical_structure ,Dyspareunia ,Reproductive Medicine ,Vagina ,Female ,Laparoscopy ,medicine.symptom ,business - Abstract
The histological relationships between fibrotic tissue, endometriotic foci and nerves in the rectovaginal septum endometriotic or adenomyotic nodule were studied. This is considered to be one of the most severe forms of deep endometriosis. Masson's trichrome staining for fibrosis detection and immunohistochemistry with the S100 monoclonal antibody for nerve detection were performed in 28 rectovaginal endometriotic nodules from patients presenting with severe dysmenorrhoea and deep dyspareunia (23 patients with no other endometriotic location or potential cause of pain at laparoscopy and ultrasonography; five patients with multiple pelvic endometriotic localizations and other potential causes of pain at laparoscopy). Patients were allocated to two groups on the basis of their preoperative pain scores for pelvic pain, dysmenorrhoea and deep dyspareunia (group 1, score >7; group 2, score < or =7). For each symptom, the mean number of nerves and endometriotic lesions per high-power field and the mean largest diameter of the lesions were not statistically different in groups 1 and 2. The mean percentages of nerves located within the fibrosis of the nodule and within endometriotic lesions were significantly higher in group 1 than in group 2. Among nerves located within endometriotic lesions, there was a significantly higher proportion showing intraneurial and perineurial invasion by endometriosis in group 1 than in group 2. In rectovaginal endometriotic nodules, there was a close histological relationship between nerves and endometriotic foci, and between nerves and the fibrotic component of the nodule. We postulate that such topographical relationships could at least partially explain the strong association between this lesion and pain.
- Published
- 2000
28. Hepatocellular carcinoma: surgical treatment and prognostic variables in 56 patients
- Author
-
J, Closset, J, Van de Stadt, M, Delhaye, I, El Nakadi, J P, Lambilliotte, and M, Gelin
- Subjects
Adult ,Aged, 80 and over ,Male ,Carcinoma, Hepatocellular ,Adolescent ,Liver Neoplasms ,Middle Aged ,Prognosis ,Liver Transplantation ,Survival Rate ,Postoperative Complications ,Liver Function Tests ,Actuarial Analysis ,Hepatectomy ,Humans ,Female ,Aged ,Neoplasm Staging - Abstract
Partial hepatectomy (PH) or total hepatectomy and orthotopic liver transplantation (OLT) may be curative in selected patients treated for hepatocellular carcinoma (HCC). The analysis of clinical series may help in the choice of the more appropriate treatment.During the past 11 years, 40 patients with HCC were treated by PH and 16 patients underwent total hepatectomy and OLT. Selection criteria for transplantation were the liver function and the tumor resectability.The actuarial 1-, 3- and 5-year survival rates were 67%, 34% and 18%, respectively, after PH and 62%, 54% and 54% after OLT. The only prognostic factor after PH was the tumor extension to a single or both lobes. Patients with associated cirrhosis had significantly more post-operative complications, but a comparable long-term survival. The proliferative cell nuclear antigen labeling index (PCNA-LI), evaluated on tumoral tissue in 16 patients, showed that an index30% indicates a better prognosis for HCC developing in non-cirrhotic liver.For patients carefully pre-operatively evaluated, the presence of an associated cirrhosis does not seem to modify the long-term survival after PH, and OLT may offer more than 50% 5-year survival. A PCNA-LI30% appears to be a good prognostic factor in patients without cirrhosis.
- Published
- 1999
29. Preoperative endoscopic retrograde cholangiopancreatography: therapeutic impact in a general population of patients needing a cholecystectomy
- Author
-
C H, Huynh, J, Van de Stadt, J, Devière, A, Mehdi, I, el Nakadi, M, Cremer, J P, Lambilliotte, and M, Gelin
- Subjects
Adult ,Aged, 80 and over ,Cholangiopancreatography, Endoscopic Retrograde ,Male ,Cholangitis ,Biliary Tract Diseases ,Bile Duct Diseases ,Length of Stay ,Middle Aged ,Sphincterotomy, Endoscopic ,Cholecystectomy, Laparoscopic ,Cholelithiasis ,Preoperative Care ,Cholecystitis ,Humans ,Cholecystectomy ,Female ,Aged ,Retrospective Studies - Abstract
The place of endoscopic retrograde cholangiopancreatography (ERCP) before open or laparoscopic cholecystectomy remains controversial. Most of the reports study highly selected series of patients and therefore do not give a survey of the actual situation in a general population. We describe here the therapeutic impact of preoperative ERCP in a continuous cohort of patients needing a cholecystectomy.Data concerning a 2-year continuous and unselected series of 452 patients undergoing cholecystectomy were evaluated.Two hundred ninety-three patients (65%) presented with a chronic symptomatic biliary lithiasis and 159 patients (35%) with a complicated biliary lithiasis. A preoperative ERCP was performed in 206 patients, all presenting with a suspicion of associated lithiasis of the common bile duct (CBD). An endoscopic sphincterotomy was performed in 106 patients: 44 patients presented with CBD stones (9.7%), all successfully cleared by endoscopy. Laparoscopic cholecystectomy has been attempted in 367 patients (81%) and successfully performed in 333 patients (74%). Laparotomy as a first-choice procedure was performed in 85 patients (19%). Surgical choledochotomy was never performed. Postoperative ERCP was needed in 4 patients (0.88%) and in only 1 of them for a retained CBD stone (0.22%).In a continuous series of patients needing a cholecystectomy, preoperative ERCP was performed on the basis of suspected CBD disorders. It allows CBD stone detection and extraction in almost 10% of the patients and avoids peroperative CBD exploration, with a very low rate of retained stones after surgery. The association of preoperative ERCP with subsequent laparoscopic cholecystectomy (when feasible) offers the patient a quick recovery and a short hospital stay.
- Published
- 1996
30. Adenocarcinoma of the ileum. A case report, and review of the literature
- Author
-
B, Mboti, I, el Nakadi, J, Closset, A, Mehdi, F, Gay, M O, Peny, and M, Zalcman
- Subjects
Ileal Neoplasms ,Male ,Sex Factors ,Palliative Care ,Humans ,Female ,Neoplasm Invasiveness ,Adenocarcinoma ,Middle Aged ,Intestinal Obstruction - Abstract
A 47-year-old female presented with intestinal occlusion and a lower abdominal mass. On laparotomy, a 10 cm diameter mass was discovered involving the ileum, jejunum, vagina and the bladder. Pathological studies conclusion was a primary adenocarcinoma of the ileum involving the jejunum. Small bowel carcinoma is rare. It occurs between sixty- and seventy-year-old equally in male and female. It presents most frequently in the duodenum, sometimes in the jejunum, and occasionally in the ileum. The symptoms are not specific and do not point to the diagnosis which must be made radiologically and endoscopically. Currently, for a minority of patients, surgical resection remains the only hope of cure. Palliative resections and bypass procedures can prevent occlusion or subocclusion.
- Published
- 1995
31. Hernia of the diaphragm: a clinical case and review of the literature
- Author
-
A, Mehdi, J, Closset, I, el Nakadi, J J, Houben, I, Veys, and J P, Lambilliotte
- Subjects
Adult ,Diagnostic Imaging ,Male ,Rib Fractures ,Thoracic Injuries ,Humans ,Wounds, Nonpenetrating ,Hernia, Diaphragmatic, Traumatic - Abstract
Diaphragmatic rupture occurs in 25% of the thoracic and abdominal blunt injuries. It may be discovered immediately or sometimes several months or even years after the trauma. The diagnosis can be made easily on the basis of a standard chest X-ray. Barium swallow examination, computerized tomography Scan and especially Magnetic resonance imaging can be helpful for differential diagnosis. Surgical treatment is always necessary.
- Published
- 1995
32. Billary strictures (hilar or anastomotic) after liver transplantation (LT)
- Author
-
M. Adler, O. Le Moine, I. El Nakadi, Michel Gelin, Hubert Louis, Celso Matos, Nadine Bourgeois, Catherine Winant, V. Lefèbvre, Nathalie Boon, J. Devière, F. Hut, Vincent Donckier, and Th. Gustoi
- Subjects
medicine.medical_specialty ,Hepatology ,business.industry ,medicine.medical_treatment ,medicine ,Liver transplantation ,Anastomosis ,business ,Surgery - Published
- 2002
- Full Text
- View/download PDF
33. 6074 POSTER Cytoreductive Surgery and HIPEC in Patients With Peritoneal Carcinomatosis of Colorectal and Appendicular Origin – Results
- Author
-
Fikri Bouazza, A. Deleporte, I. El Nakadi, K. Kothonidis, M. Ben Aziz, A. Covas, Alain Hendlisz, Gabriel Liberale, and K. Keriakos
- Subjects
Cancer Research ,medicine.medical_specialty ,Oncology ,business.industry ,medicine ,In patient ,Cytoreductive surgery ,business ,Surgery ,Peritoneal carcinomatosis - Published
- 2011
- Full Text
- View/download PDF
34. 3023 POSTER Prospective Study on Satisfaction and Quality of Life of Oncological Patients Who Underwent TIVAD Placement
- Author
-
Michel Moreau, Gabriel Liberale, K. Kothonidis, I. El Nakadi, Fikri Bouazza, K. Keriakos, and B. Fernez
- Subjects
Cancer Research ,medicine.medical_specialty ,Oncology ,Quality of life ,business.industry ,General surgery ,Medicine ,business ,Prospective cohort study ,Surgery - Published
- 2011
- Full Text
- View/download PDF
35. Results of surgical resection for hepatocellular carcinoma
- Author
-
J, Closset, M, Gelin, I, el Nakadi, J, Van de Stadt, and J P, Lambilliotte
- Subjects
Adult ,Aged, 80 and over ,Liver Cirrhosis ,Male ,Carcinoma, Hepatocellular ,Adolescent ,Liver Neoplasms ,Middle Aged ,Prognosis ,Severity of Illness Index ,Survival Rate ,Postoperative Complications ,Actuarial Analysis ,Risk Factors ,Hepatectomy ,Humans ,Female ,Hospital Mortality ,Aged ,Follow-Up Studies - Abstract
During the past 13-years, 35 patients with hepatocellular carcinoma (HCC) were treated by hepatic resection. There were 11 females and 24 males, the age ranged from 17 to 82 years with a mean of 59 years. HCC was associated with liver cirrhosis in 17 patients (48%). Fifteen patients underwent a major hepatectomy, 18 patients a partial hepatectomy (single or bisegmentectomy) and 2 patients had a wedge resection. One patient presenting with a spontaneous tumor rupture died immediately after surgery. Out of the 34 others, 3 died in the postoperative period (8.8%). Early complications occurred in 57% of the patients. The actuarial 5-years survival rate is 30%. The only prognostic factor is tumor extension to a single or both lobes. A significant difference in the survival rate has been observed between patients with or without underlying cirrhosis. Our experience suggest that long-term survival can be expected after surgical resection for HCC.
- Published
- 1993
36. 5091 Predictive role of Her-2 receptors on primary tumour in patients with liver metastases from breast cancer treated by surgery
- Author
-
F. Bastin, Gabriel Liberale, Fikri Bouazza, E. Guérin, N. Sirtaine, I. El Nakadi, Ahmad Awada, V. Lucidi, Vincent Donckier, and Isabelle Veys
- Subjects
Oncology ,CA15-3 ,Cancer Research ,medicine.medical_specialty ,business.industry ,Cancer ,medicine.disease ,Breast cancer ,Internal medicine ,medicine ,In patient ,Receptor ,business - Published
- 2009
- Full Text
- View/download PDF
37. 2104 The role of FDG PET (CT) for diagnosis of peritoneal carcinomatosis of colorectal origin
- Author
-
I. El Nakadi, C. Lecocq, G. Andry, Gabriel Liberale, K. Muylle, Camilo Garcia, Patrick Flamen, and A. Covas
- Subjects
Cancer Research ,medicine.medical_specialty ,Oncology ,business.industry ,Medicine ,Fdg pet ct ,Radiology ,business ,Peritoneal carcinomatosis - Published
- 2009
- Full Text
- View/download PDF
38. [Solitary diverticulum of the cecum: apropos of 2 cases]
- Author
-
B, el Nakadi, M, Greuse, and I, el Nakadi
- Subjects
Male ,Cecal Diseases ,Humans ,Female ,Middle Aged ,Diverticulitis ,Aged ,Ultrasonography - Abstract
Diverticulitis of the cecum and ascending colon represent 1.5% of colonic diverticulitis. The preoperative diagnosis is made in 0 to 23% of cases. Two typically misdiagnosed cases are reported. A review of the literature reveals that CT Scan is useful when atypical pain is present in the right lower quadrant. If diagnosed preoperatively, the uncomplicated caecal diverticulitis can be managed conservatively.
- Published
- 1990
39. Wilkie's syndrome
- Author
-
V. Muls, Jean Closset, Michel Gelin, I. El Nakadi, A.M. Nana, J. Jeanmart, A. Van Gossum, and J. Kouame
- Subjects
Adult ,medicine.medical_specialty ,Adolescent ,Normal diet ,Duodenum ,Superior Mesenteric Artery Syndrome ,Anastomosis ,Epigastric pain ,Therapeutic approach ,Internal medicine ,Humans ,Medicine ,Laparoscopy ,Digestive System Surgical Procedures ,medicine.diagnostic_test ,business.industry ,Hepatology ,medicine.disease ,Surgery ,Jejunum ,Female ,business ,Superior mesenteric artery syndrome ,Abdominal surgery - Abstract
A superior mesenteric artery syndrome (SMAS) was diagnosed in two young women with, respectively, a 2- and 1-year history of postprandial vomiting and epigastric pain. The patients underwent a laparoscopic duodenojejunal bypass, and resumed a normal diet on the fifth postoperative day. The patients are still symptom-free with patent anastomosis on gastrointestinal radiographic control at 24 and 6 months, respectively, following their operation. Herein we also describe the varying clinical presentation of this rare syndrome, as well as treatment options. We conclude that laparoscopic duodenojejunostomy offers a new therapeutic approach to SMAS. It is reliable and safe; the operating time is acceptable; and diet recovery and hospital stay are both short. However, these preliminary results still need to be confirmed by further observations.
- Published
- 2003
- Full Text
- View/download PDF
40. A role for low density lipoproteins (LDL) in the inflammatory response to surgical injury?
- Author
-
I. El Nakadi, M. Richelle, Michel Gelin, D.Y. Dubois, Brigitte Ickx, Vania Siderova, and Yvon Carpentier
- Subjects
medicine.medical_specialty ,Nutrition and Dietetics ,business.industry ,Internal medicine ,Inflammatory response ,Low density ,medicine ,Critical Care and Intensive Care Medicine ,business ,Surgical Injury ,Gastroenterology - Published
- 1994
- Full Text
- View/download PDF
41. A giant parastomal hernia in a high risk patient: preparation to make surgery worthwhile.
- Author
-
Gunes S, Bohlok A, El Asmar A, Engels T, Lefort MM, Farinella E, and El Nakadi I
- Subjects
- Male, Humans, Aged, Quality of Life, Colostomy adverse effects, Peritoneum surgery, Surgical Mesh adverse effects, Hernia, Ventral surgery, Surgical Stomas adverse effects
- Abstract
Background: Parastomal hernia (PH) is a frequent and well-known complication of stoma placement. Most PHs are asymptomatic and those who are not are usually well tolerated by patients. Thus, watchful waiting is a common practice. Nevertheless, this management policy is associated with a risk of complications and with an inevitable risk of hernia enlargement, complicating its subsequent surgery. Moreover, PH can affect body image and alter the quality of life., Methods: We herein present a complex case of a 67-year-old man with multiple comorbidities, who presented with an uncommon, below knee, giant PH, which was managed in a two-steps surgery by a multidisciplinary team comprising a senior digestive surgeon, experienced in abdominal wall repair, cardiologist, pulmonologist, anesthesiologist, psychiatrist, dietitian and physiotherapist., Result: Treatment started with 8 months hygienic measures comprising smoking cessation, strict control of diabetes and hypertension, a strict diet, and a physical fitness and pulmonary rehabilitation program. Two steps surgery started by colostomy transposition along with pre-peritoneal mesh repair to the right side and the second step consisted of a prophylactic PH repair using a Key-hole preperitoneal polypropelene mesh., Conclusion: PH is a common and sometimes inevitable complication of stoma creation. The success achieved by operating a heavily morbid patient, is only possible through the combined efforts of the multidisciplinary team and a preoperative rigorous management.
- Published
- 2023
- Full Text
- View/download PDF
42. Esophageal cancer: Outcome and potential benefit of esophagectomy in elderly patients.
- Author
-
Laurent A, Marechal R, Farinella E, Bouazza F, Charaf Y, Gay F, Van Laethem JL, Gonsette K, and El Nakadi I
- Subjects
- Aged, Disease-Free Survival, Esophagectomy, Humans, Neoadjuvant Therapy, Retrospective Studies, Treatment Outcome, Carcinoma, Squamous Cell pathology, Esophageal Neoplasms pathology
- Abstract
Background: This analysis evaluated the morbimortality and the potential benefit of esophagectomy for cancer in elderly patients., Methods: Patients who underwent esophagectomy for EC were divided into elderly (≥70 years) and nonelderly (<70 years) groups. The groups were compared regarding patient and tumor characteristics, postoperative morbimortality, and disease-free, overall and cancer-specific survival., Results: Sixty-one patients were classified into elderly, and 187 into nonelderly groups. The elderly were characterized by a higher rate of WHO score (p < 0.0001), higher cardiac (p < 0.004) and renal (p < 0.023) comorbidities. The rate of neoadjuvant therapy and especially of neoadjuvant CRT was significantly lower in elderly patients (p < 0.018 and p < 0.007). Operative morbidity was also higher in this group (p < 0.024). The 30- and 90-day mortality was 8.2 and 11.5%, respectively in elderly patients and 0.5 and 3.2% in nonelderly patients (p < 0.004 and p < 0.012). This 90-day mortality decreased when specific surgery-related deaths were taken into consideration. OS and DFS were significantly better in the nonelderly group (p < 0.003 and p < 0.005) while no difference was observed for cancer-specific survival (CSS)., Conclusion: No difference in CSS was observed. Although elderly patients with EC had higher postoperative morbimortality, the age should not be a criterion whether to perform, or not to perform, esophagectomy. This decision must be based on the balance between the patient's general condition and aggressive disease., (© 2022 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd.)
- Published
- 2022
- Full Text
- View/download PDF
43. Isolated oesophageal Crohn's disease mimicking oesophageal carcinoma treated by Merendino procedure.
- Author
-
Al Zoghby S, Bohlok A, Moschopoulos C, Toussaint E, Verset L, Demetter P, and El NAkadi I
- Subjects
- Aged, Deglutition Disorders etiology, Diagnosis, Differential, Esophageal Neoplasms, Female, Humans, Weight Loss, Crohn Disease diagnosis, Crohn Disease surgery, Esophageal Diseases diagnosis, Esophageal Diseases surgery
- Abstract
Oesophageal involvement is a very rare presentation of Crohn's disease. It can occur as an isolated mass causing dysphagia and can be mistaken for malignancy. Here, we report a case of a 75-year-old woman presenting with dysphagia and weight loss. Gastroscopy showed an ulcerating mass, and her barium swallow showed a bird beak appearance at the level of the gastro-oesophageal junction (GEJ). Repetitive biopsies were inconclusive. Fluorodeoxyglucose-positron emission tomography showed high glucose uptake (standardised uptake value: 10.2) at the level of the GEJ. Endoscopic ultrasound classified the lesion as uT3N1. Step-by-step surgical exploration revealed an oesophageal mass. A frozen section examination showed an absence of malignancy and the presence of inflammatory tissue. A partial oesophagogastrostomy was performed, and reconstruction was achieved by a Merendino procedure. Definitive histopathological examination revealed isolated oesophageal Crohn's disease.
- Published
- 2022
- Full Text
- View/download PDF
44. A Surgical Alternative in the Treatment of Recurrent Diaphragmatic Hernia after Total Gastrectomy.
- Author
-
Abboud NM, Rimbault M, Abboud S, El Nakadi I, and Charara FG
- Abstract
Treament of hiatal hernia remains a challenge for surgeons. The techniques for treatment started with cruroplasty, which was later associated with extensive mobilization of the esophagus, with or without fundoplication. Other solutions included the use of synthetic or biological mesh and autologous tissue reinforcement. Despite these therapeutic strategies, the recurrence rate for hiatal hernia is significant, and no existing treatments have had much success in reducing this rate. Total gastrectomy, as in this case, represents an additional challenge because of the absence of gastric tissue, which can buttress the pillars' repair. This case report introduces a novel approach for the treatment of recurrent hiatal hernia, using a pedicled vertical rectus abdominis myocutaneous flap., (Copyright © 2020 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons.)
- Published
- 2020
- Full Text
- View/download PDF
45. The burden of low anterior resection syndrome on quality of life in patients with mid or low rectal cancer.
- Author
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Bohlok A, Mercier C, Bouazza F, Galdon MG, Moretti L, Donckier V, El Nakadi I, and Liberale G
- Subjects
- Female, Humans, Male, Middle Aged, Prospective Studies, Syndrome, Postoperative Complications etiology, Quality of Life psychology, Rectal Neoplasms surgery
- Abstract
Background: Low anterior resection (LAR) with total mesorectal excision (TME) for mid and low rectal cancer is standard of care, reducing local recurrence and enhancing long-term survival. However, this surgery is associated with a constellation of major defecatory problems that are collectively referred to as low anterior resection syndrome (LARS). The aims of this study were to evaluate the frequency of LARS in patients who have undergone LAR and to assess the impact of LARS on long-term quality of life (QoL)., Methods: This was a single-center prospective survey study on patients who underwent LAR and TME for low or mid rectal cancer between 2007 and 2015. LARS score and QLQ-C30 questionnaires were used to evaluate patient's bowel functions and quality of life, respectively. Associations between LARS and QoL were evaluated., Results: Fifty-seven patients out of 65 eligible agreed to participate in the study. Forty-three (66%) patients returned complete questionnaires. Five patients (11.6%) had no LARS, 7 had minor LARS (16.3%), and 31 had major LARS (72.1%). In univariate analysis, BMI > 30 kg/m
2 was predictive of major LARS (p = 0.047). Major LARS did not impair global QoL (p = 0.75), function scores, or social scales, and was not associated with any of the symptom scores except for diarrhea (p = 0.02)., Conclusion: LARS is a frequent occurrence after LAR and TME for rectal cancer (72.1%) and is more prevalent in morbidly obese patients. However, the occurrence of LARS does not appear to have a direct impact on QoL except for the occurrence of diarrhea.- Published
- 2020
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46. A rare presentation of small diaphragmatic epidermoid cyst with extremely elevated serum CA19-9 level.
- Author
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El-Khoury M, Bohlok A, Sleiman YA, Loi P, Coppens E, Demetter P, and El Nakadi I
- Subjects
- Biomarkers blood, Diaphragm surgery, Epidermal Cyst surgery, Female, Humans, Middle Aged, Positron-Emission Tomography, Tomography, X-Ray Computed, CA-19-9 Antigen blood, Diaphragm diagnostic imaging, Epidermal Cyst diagnosis
- Abstract
Epidermoid cysts are rare lesions that can occur anywhere in the body. They are associated with elevated serum levels of CA 19-9. The spleen represents the most common site of intra-abdominal localisation. Only two cases of diaphragmatic epidermoid cyst are reported in the literature. We present the case of a 61-year-old woman with a small suprasplenic subdiaphragmatic cyst discovered during the investigation of left flank pain. The establishment of an adequate diagnosis was challenging due to the difficulty in specifying the exact localisation of the cyst, the extremely elevated CA 19-9 level of 19,000 and the high uptake on 18-fluoro-2-deoxy-D-glucose positron emission tomography. The definitive diagnosis followed complete surgical excision. Intra-abdominal epidermoid cysts are usually discovered incidentally on imaging for another reason. The cyst is lined by squamous epithelium responsible for the secretion of CA 19-9. The elevation of serum CA 19-9 is due to small rupture or increased intraluminal pressure followed by diffusion to the bloodstream. Surgery with en-bloc resection represents the optimal treatment to avoid any risk of recurrence. The definitive diagnosis is established by demonstrating positive immunohistopathological staining of epithelial cell to CA 19.9.
- Published
- 2020
- Full Text
- View/download PDF
47. Hiatal hernia after oesophagectomy: a large European survey.
- Author
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Gust L, Nafteux P, Allemann P, Tuech JJ, El Nakadi I, Collet D, Goere D, Fabre JM, Meunier B, Dumont F, Poncet G, Passot G, Carrere N, Mathonnet M, Lebreton G, Theraux J, Marchal F, Barabino G, Thomas PA, Piessen G, and D'Journo XB
- Subjects
- Esophageal Neoplasms surgery, Female, Follow-Up Studies, Hernia, Hiatal surgery, Humans, Male, Middle Aged, Postoperative Complications surgery, Reoperation, Retrospective Studies, Time Factors, Treatment Outcome, Esophagectomy adverse effects, Hernia, Hiatal etiology, Herniorrhaphy methods, Laparoscopy methods, Postoperative Complications etiology, Thoracotomy methods
- Abstract
Objectives: Hiatal hernias (HH) after oesophagectomy are rare, and their surgical management is not well standardized. Our goal was to report on the management of HH after oesophagectomy in high-volume tertiary European French-speaking centres., Methods: We conducted a retrospective multicentre study among 19 European French-speaking departments of upper gastrointestinal and/or thoracic surgery. All patients scheduled or operated on for the repair of an HH after oesophagectomy were collected between 2000 and 2016. Demographics, details of the initial procedure, surgical management and long-term outcome were analysed., Results: Seventy-nine of 6608 (1.2%) patients who had oesophagectomies were included in the study. The postoesophagectomy diagnostic interval of an HH after oesophagectomy was ≤90 days (n = 17; 21%), 13 were emergency cases; between 91 days and 1 year, n = 21 (27%), 13 in emergency; ≥1 year, n = 41 (52%), 17 in emergency. The time to occurrence of HH after oesophagectomy was shorter after laparoscopy (median 308 days; interquartile range 150-693) compared to that after laparotomy (median 562 days, interquartile range 138-1768; P = 0.01). The incidence of HH after oesophagectomy was 0.73% (22/3010) after open surgery and 1.4% (26/1761) after laparoscopy (P = 0.03). Among the 79 patients, 78 were operated on: 35 had laparotomies (45%), 19 had laparoscopies (24%) and 24 (31%) had transthoracic approaches. Among the 43 urgent surgeries, 35 were open (25 laparotomies and 10 transthoracic approaches) and 8 were laparoscopies (conversion rate, 25%). Nine patients required bowel resections. Morbidity occurred in 36 (46%) patients with 1 postoperative death (1.2%). During the follow-up period, recurrent HH after oesophagectomy requiring revisional surgery developed in 8 (6 days-26 months) patients., Conclusions: Surgical management of HH after oesophagectomy could be done by laparoscopy in patients with scheduled surgery but laparotomy or thoracotomy was preferred in urgent situations. The incidence of HH after oesophagectomy is higher and its onset earlier when laparoscopy is used at the initial oesophagectomy., (© The Author(s) 2018. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.)
- Published
- 2019
- Full Text
- View/download PDF
48. The potential benefit of adjuvant chemotherapy in locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy is not predicted by tumor regression grade.
- Author
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Bohlok A, Hendlisz A, Bouazza F, Galdon MG, Van de Stadt J, Moretti L, El Nakadi I, and Liberale G
- Subjects
- Adult, Aged, Aged, 80 and over, Chemoradiotherapy, Chemoradiotherapy, Adjuvant, Chemotherapy, Adjuvant, Disease-Free Survival, Female, Humans, Male, Middle Aged, Neoplasm Staging, Prospective Studies, Rectal Neoplasms surgery, Retrospective Studies, Treatment Outcome, Neoadjuvant Therapy, Rectal Neoplasms drug therapy
- Abstract
Introduction: Recommended treatment for locally advanced rectal cancer (LARC) is neoadjuvant chemoradiotherapy (NACRT) followed by surgery and total mesorectal excision (TME). The role of adjuvant chemotherapy (ACT) in this regimen is still debated. Assessment of Dworak's tumor regression grade (TRG) after NACRT could potentially select patients who might benefit from ACT., Materials and Methods: Data for patients who underwent NACRT and TME for LARC between 2007 and 2014 were retrieved from the Bordet Institute database. Overall survival (OS) and disease-free survival (DFS) were calculated for the whole population, according to whether or not they received ACT, and according to TRG., Results: We included 74 patients (38 males) with a median age of 62.7 years (33-84 years). AJCC stage cIIIb disease was the most frequent (73%). Pathologic complete response (pCR) was achieved in 13 patients (17.6%). ACT was administered to 42 patients (56.8%). Five-year OS and DFS of patients who received ACT or not were 92 and 84.5% (p = ns), and 79.9 and 84.8% (p = ns), respectively. OS was related to TRG (cut-off value of 3) (p = 0.001). ACT administration was not correlated with improved outcomes in any TRG groups., Conclusion: TRG is a prognostic factor for both OS and DFS but does not appear to have a significant benefit for the selection of patients with LARC treated with NACRT who might benefit from the administration of ACT. Prospective randomized trials with larger populations are needed to identify factors that predict which patients may benefit from the administration of ACT.
- Published
- 2018
- Full Text
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49. Indocyanine green fluorescence imaging for sentinel lymph node detection in colorectal cancer: A systematic review.
- Author
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Liberale G, Bohlok A, Bormans A, Bouazza F, Galdon MG, El Nakadi I, Bourgeois P, and Donckier V
- Subjects
- Colorectal Neoplasms diagnosis, Fluorescence, Fluorescent Dyes, Humans, Lymphatic Metastasis, Colorectal Neoplasms secondary, Indocyanine Green pharmacology, Optical Imaging methods, Sentinel Lymph Node pathology
- Abstract
Indocyanine green fluorescence-imaging (ICG-FI) has emerged as a potential tool for increasing the accuracy of staging of patients with primary colorectal cancer (CRC) through the detection of sentinel lymph nodes (SLNs). Here, we report the results of a systematic review of the available literature in the clinical setting of ex vivo and in vivo ICG-FI for the detection of SLNs in primary colorectal cancer. PubMed, Scopus, and Cochrane literature databases were searched for original articles on the use of ICG in the setting of clinical studies of CRC. Eighty studies were identified and screened, 23 were assessed for eligibility and 10 were included for review. Both ex vivo and in vivo ICG-FI are reported to be feasible for the detection of SLNs in CRC. The reported sensitivity of both techniques remains low, varying from 0% to 100% for the in vivo technique and 57% for the ex vivo technique. ICG-FI has not yet been shown to perform better than the standard blue dye technique. In addition, large variability among reported studies in terms of techniques used (ICG dose, type of injection), type of pathologic analyses performed (HE, IHC, serial section), and definition of positive LN status for sensitivity calculations made them difficult to compare directly. ICG-FI is a promising technique for the detection of SLNs in the setting of CRC but more work needs to be done to clearly define protocols and indications for its use and to test its efficacy in larger patient populations., (Copyright © 2018 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.)
- Published
- 2018
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50. Different laparoscopic treatment modalities for splenic artery aneurysms: about 3 cases with review of the literature.
- Author
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Nasser HA, Kansoun AH, Sleiman YA, Mendes VM, Van Vyve E, Kachi A, Berjawi T, Hamdan WS, and El Nakadi I
- Subjects
- Aged, Aneurysm diagnosis, Computed Tomography Angiography, Female, Humans, Male, Middle Aged, Aneurysm surgery, Laparoscopy methods, Splenectomy methods, Splenic Artery, Vascular Surgical Procedures methods
- Abstract
Introduction: The first laparoscopic treatment of splenic artery aneurysm (SAA) was performed in 1993. Since then, many papers have been published mentioning different laparoscopic treatment modalities, including splenectomy, aneurysmectomy, ligation or even occlusion., Patients and Methods: An updated literature review of the English medical literature using the following MeSH, 'Lapaorscopic splenic artery aneurysm', 'laparoscopic aneurysectomy', 'Laparoscopic Splenic artery Aneurysm Ligation' and 'Laparoscopic Splenic artery aneurysm excision' was done. Also three cases performed at our institutions are discussed, in terms of techniques, morbidity, mortality and postoperative outcomes., Results: About eight case series and 16 case reports were retrieved from the literature. Different techniques were described by the authors, including splenectomy, aneurysmectomy, splenic aneurysm ligation or even occlusion. Few morbidity cases were reported and none of the authors has mentioned a single mortality case. In our three cases, the postoperative course was uneventful, with good long-term results., Conclusions: Despite the variations in the adopted operative techniques, the laparoscopic approach seems to be harmless. However, no treatment algorithm or consensus has been published.
- Published
- 2018
- Full Text
- View/download PDF
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