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Your search keyword '"Hyun, Hye Sun"' showing total 126 results
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126 results on '"Hyun, Hye Sun"'

3. Lower albumin level and longer disease duration are risk factors of acute kidney injury in hospitalized children with nephrotic syndrome

Author

Yang, Eun Mi, Yoo, Kee Hwan, Ahn, Yo Han, Kim, Seong Heon, Lee, Jung Won, Chung, Woo Yeong, Cho, Min Hyun, Kim, Kee Hyuck, Lee, Heeyeon, Suh, Jin-Sooh, Hyun, Hye Sun, Lee, Jiwon M., Cho, Myung Hyun, Kim, Ji Hyun, Ha, Il-Soo, Cheong, Hae Il, and Kang, Hee Gyung

Subjects
Serum albumin -- Statistics -- Health aspects, Acute renal failure -- Risk factors -- Statistics, Nephrotic syndrome -- Complications and side effects -- Statistics, Hospital patients -- Statistics, Pediatric research, Health
Abstract

Background Children with nephrotic syndrome (NS) are at an increased risk of acute kidney injury (AKI) and the incidence of AKI in this population is reportedly increasing. This study aimed to investigate the incidence, clinical profiles, and risk factors of AKI in hospitalized children with NS through a nationwide study. Methods This retrospective multicenter study included 14 pediatric nephrology centers in Korea. From 2013 to 2017, a total of 814 patients with idiopathic NS were cared for at participating centers. Among them, 363 patients were hospitalized for NS and investigated in this study. Results A total of 363 children with NS were hospitalized 574 times. AKI occurred in 93 admissions (16.2%) of 89 patients: 30 (32.3%) stage 1; 24 (25.8%) stage 2; and 39 (41.9%) stage 3. Multivariate logistic regression analysis showed that longer disease duration, lower albumin level, and methylprednisolone pulse treatment were significantly associated with AKI development in hospitalized children with NS. AKI was associated with a longer hospital stay than non-AKI (median 10 vs. 7 days, P = 0.001). Among 93 admissions, 85 (91.4%) episodes recovered from AKI without complication, whereas 6 (6.5%) progressed to advanced chronic kidney disease (CKD). Conclusions AKI is not uncommon in hospitalized children with NS, and its incidence in this nationwide study was 16.2%. Risk factors for AKI in hospitalized children with NS include longer disease duration, lower albumin level, and methylprednisolone pulse therapy. Pediatric NS patients with these characteristics should be under more strict scrutiny for the occurrence of AKI., Author(s): Eun Mi Yang [sup.1] , Kee Hwan Yoo [sup.2] , Yo Han Ahn [sup.3] , Seong Heon Kim [sup.4] , Jung Won Lee [sup.5] , Woo Yeong Chung [sup.6] [...]

Published
2020
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4. Low relapse rate of urinary tract infections from extended-spectrum beta-lactamase-producing bacteria in young children

Author

Hyun, Hye Sun, Kim, Ji Hye, Cho, Myung Hyun, Park, Eujin, Ha, Il-Soo, Cheong, Hae Il, and Kang, Hee Gyung

Subjects
Urinary tract infections -- Care and treatment, Beta lactamases -- Research, Adult children -- Health aspects, Escherichia coli -- Research, Health
Abstract

Background Extended-spectrum-beta-lactamase (ESBL)-producing bacteria are an increasingly important cause of urinary tract infections (UTIs) worldwide. We evaluated clinical characteristics and associated risk factors of UTIs in young children according to ESBL-producing status and relapse rates. Methods All urinary culture results in patients younger than 2 years old were assessed, and only children with febrile UTIs from gram-negative bacterial infections were reviewed. Results Of 845 episodes evaluated, 146 (17.3%) were caused by ESBL-positive bacteria. Significant differences were observed in previous UTIs, use of antibiotics or history of hospitalization within previous 3 months, and underlying urinary abnormalities between the ESBL UTI and non-ESBL UTI groups. After 2 weeks of treatment completion, UTI relapse occurred in 2.7% of children in the ESBL group and 1.1% of children in the non-ESBL group (P = 0.13). In the ESBL UTI group, relapse rate was not significantly different between patients treated with susceptible antibiotics and those treated with non-susceptible but clinically effective antibiotics. Conclusions Previous history of UTI, antibiotic treatment, or hospitalization within previous 3 months and underlying disease are risk factors for ESBL UTI in children under 24 months of age. However, relapse rate was < 3% regardless of in vitro susceptibility of the treating antibiotics, as long as the antibiotics were clinically effective. We cautiously propose that we may continue the use of initial empirical antibiotics when a definite clinical response is observed, although further study is necessary to confirm the findings of this study., Author(s): Hye Sun Hyun [sup.1] [sup.2] , Ji Hye Kim [sup.3] , Myung Hyun Cho [sup.3] , Eujin Park [sup.2] [sup.4] , Il-Soo Ha [sup.2] [sup.3] , Hae Il Cheong [...]

Published
2019
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8. Characteristics of pediatric rhabdomyolysis and the associated risk factors for acute kidney injury: a retrospective multicenter study in Korea

Author

Yoo, Sukdong, Cho, Min Hyun, Baek, Hee Sun, Song, Ji Yeon, Lee, Hye Sun, Yang, Eun Mi, Yoo, Kee Hwan, Kim, Su Jin, Shin, Jae Il, Lee, Keum Hwa, Ha, Tae-Sun, Jang, Kyung Mi, Lee, Jung Won, Kim, Kee Hyuck, Cho, Heeyeon, Lee, Mee Jeong, Suh, Jin-Soon, Han, Kyoung Hee, Hyun, Hye Sun, Ha, Il-Soo, Cheong, Hae Il, Kang, Hee Gyung, Namgoong, Mee Kyung, Cho, Hye-Kyung, Oh, Jae-Hyuk, Lee, Sang Taek, Kim, Kyo Sun, Lee, Joo Hoon, Park, Young Seo, and Kim, Seong Heon

Subjects
myalgia, medicine.medical_specialty, Etiology, biology, business.industry, Muscles, Incidence (epidemiology), Acute kidney injury, Retrospective cohort study, General Medicine, urologic and male genital diseases, medicine.disease, Internal medicine, biology.protein, Medicine, Original Article, Creatine kinase, Renal insufficiency, medicine.symptom, business, Rhabdomyolysis, Body mass index
Abstract

Background The clinical features of pediatric rhabdomyolysis differ from those of the adults with rhabdomyolysis; however, multicenter studies are lacking. This study aimed to investigate the characteristics of pediatric rhabdomyolysis and reveal the risk factors for acute kidney injury (AKI) in such cases. Methods This retrospective study analyzed the medical records of children and adolescents diagnosed with rhabdomyolysis at 23 hospitals in South Korea between January 2007 and December 2016. Results Among 880 patients, those aged 3 to 5 years old composed the largest subgroup (19.4%), and all age subgroups were predominantly male. The incidence of AKI was 11.3%. Neurological disorders (53.6%) and infection (39.0%) were the most common underlying disorder and cause of rhabdomyolysis, respectively. The median age at diagnosis in the AKI subgroup was older than that in the non-AKI subgroup (12.2 years vs. 8.0 years). There were no significant differences in body mass index, myalgia, dark-colored urine, or the number of causal factors between the two AKI-status subgroups. The multivariate logistic regression model indicated that the following factors were independently associated with AKI: multiorgan failure, presence of an underlying disorder, strong positive urine occult blood, increased aspartate aminotransferase and uric acid levels, and reduced calcium levels. Conclusions Our study revealed characteristic clinical and laboratory features of rhabdomyolysis in a Korean pediatric population and highlighted the risk factors for AKI in these cases. Our findings will contribute to a greater understanding of pediatric rhabdomyolysis and may enable early intervention against rhabdomyolysis-induced AKI.

Published
2021
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22. Reninoma: a rare cause of curable hypertension

Author

Kim, Ji Hye, primary, Kim, Ji Hyun, additional, Cho, Myung Hyun, additional, Park, Eujin, additional, Hyun, Hye Sun, additional, Ahn, Yo Han, additional, Kang, Hee Gyung, additional, Moon, Kyung Chul, additional, Ha, Il-Soo, additional, and Cheong, Hae Il, additional

Published
2019
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24. A Study on the Relationship between Fatigue Level, Job Stress and Quality of Life for Workers

Author

Hyun， Hye Sun and Yunyoung， Kim

Subjects
Gerontology, Health promotion, Job stress, Quality of life, business.industry, Health care service, Medicine, Negative correlation, business
Abstract

Purpose: The purpose of this study was to seek ways to improve the quality of life of workers by separating workers into the low fatigue group and the severe fatigue group depending on the level of fatigue level, and analyzing and understanding the difference between quality of life and job stress according to the fatigue level. Methods: For the ‘Development of Mibyeong management system which was a consumer-directed health care service’, the data of job stress, fatigue and quality of life was collected from 115 workers who visited the oriental hospitals located in J city and C city from Jul, 2012 to Dec, 2012. Results: The severe fatigue group showed significantly higher job stress than the low fatigue group in physical environment (p=.004), job demand (p

Published
2015
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26. Clinical Significance of Crescent Formation in IgA Nephropathy – a Multicenter Validation Study

Author

Park, Sehoon , primary, Baek, Chung Hee , additional, Park, Su-Kil , additional, Kang, Hee Gyung , additional, Hyun, Hye Sun , additional, Park, Eujin , additional, Han, Seung Hyeok , additional, Ryu, Dong-Ryeol , additional, Kim, Dong Ki , additional, Oh, Kook-Hwan , additional, Joo, Kwon Wook , additional, Kim, Yon Su , additional, Moon, Kyung Chul , additional, Chin, Ho Jun , additional, and Lee, Hajeong , additional

Published
2019
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