Nano-fluids are produced by combining one or more nano-particles in a base-fluid. Nano-fluids, especially hybrid nano-fluids, have better thermal conductivities than simple liquids. The results of various articles demonstrated that various parameters such as nano-particles size, their volume fraction, temperature, aspect ratio, base-fluid, nano inclusions, additive, and pH affect nano-fluid thermal conductivity. In this paper, the effect of these parameters is reviewed by considering experimental works performed on thermal conductivity. Since thermal conductivity is measured by researchers experimentally, it is also important for researchers to understand the effect of nano-particles on humans and the environment. Thus, in this article, published articles in this field are reviewed and the effect of nano-particles on human and environment are investigated. The results of these articles indicated that nano-particles can endanger human health and can have irreversible effects on human health. The nano-particles also have a devastating effect on the environment and can affect the water, soil, and animals. • Nanofluids discovery has had an important impact on heat transfer. • Reviewing Brownian motion and Clustering phenomena found in nanofluids. • Reviewing effect of temperature and concentration of nanoparticles on fluids thermal conductivity. • Assessment of effect of pH values, size and shape of nanoparticles on thermal conductivity. [ABSTRACT FROM AUTHOR]