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2. Real-World Eligibility and Cost-Effectiveness Analysis of Empagliflozin for Heart Failure in Korea.

Author

Kim, Eui-Soon, Park, Sun-Kyeong, Youn, Jong-Chan, Lee, Hye, Lee, Hae-Young, Cho, Hyun-Jai, Choi, Jin-Oh, Jeon, Eun-Seok, Lee, Sang, Kim, Min-Seok, Kim, Jae-Joong, Hwang, Kyung-Kuk, Cho, Myeong-Chan, Chae, Shung, Kang, Seok-Min, Park, Jin, Choi, Dong-Ju, Yoo, Byung-Su, Cho, Jae, Kim, Kye, Oh, Byung-Hee, Greenberg, Barry, and Baek, Sang

Subjects
Cost-Effectiveness Analysis, Drug Therapy, Empagliflozin, Heart Failure, SGLT2 Inhibitors, United States, Humans, Heart Failure, Cost-Effectiveness Analysis, Prospective Studies, Stroke Volume, Republic of Korea
Abstract

BACKGROUND: The US Food and Drug Administration (FDA) and European Medicines Agency (EMA) approved empagliflozin for reducing cardiovascular mortality and heart failure (HF) hospitalization in patients with both HF with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF). However, limited data are available on the generalizability of empagliflozin to clinical practice. Therefore, we evaluated real-world eligibility and potential cost-effectiveness based on a nationwide prospective HF registry. METHODS: A total of 3,108 HFrEF and 2,070 HFpEF patients from the Korean Acute Heart Failure (KorAHF) registry were analyzed. Eligibility was estimated by inclusion and exclusion criteria of EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Reduced Ejection Fraction (EMPEROR-Reduced) and EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Preserved Ejection Fraction (EMPEROR-Preserved) trials and by FDA & EMA label criteria. The cost-utility analysis was done using a Markov model to project the lifetime medical cost and quality-adjusted life year (QALY). RESULTS: Among the KorAHF patients, 91.4% met FDA & EMA label criteria, while 44.7% met the clinical trial criteria. The incremental cost-effectiveness ratio of empagliflozin was calculated at US$6,764 per QALY in the overall population, which is far below a threshold of US$18,182 per QALY. The cost-effectiveness benefit was more evident in patients with HFrEF (US$5,012 per QALY) than HFpEF (US$8,971 per QALY). CONCLUSION: There is a large discrepancy in real-world eligibility for empagliflozin between FDA & EMA labels and clinical trial criteria. Empagliflozin is cost-effective in HF patients regardless of ejection fraction in South Korea health care setting. The efficacy and safety of empagliflozin in real-world HF patients should be further investigated for a broader range of clinical applications. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT01389843.

Published
2024

3. Eligibility and Cost-Utility Analysis of Dapagliflozin in Patients with Heart Failure Across the Whole Spectrum of Ejection Fraction in South Korea

Author

Kim, Eui-Soon, Park, Sun-Kyeong, Cho, Daniel Sung-ho, Youn, Jong-Chan, Lee, Hye Sun, Lee, Hae-Young, Cho, Hyun-Jai, Choi, Jin-Oh, Jeon, Eun-Seok, Lee, Sang Eun, Kim, Min-Seok, Kim, Jae-Joong, Hwang, Kyung-Kuk, Cho, Myeong-Chan, Chae, Shung Chull, Kang, Seok-Min, Park, Jin Joo, Choi, Dong-Ju, Yoo, Byung-Su, Cho, Jae Yeong, Kim, Kye Hun, Oh, Byung-Hee, Greenberg, Barry, and Baek, Sang Hong

Published
2024
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6. Correction: Comparison of 2‑year mortality according to obesity in stabilized patients with type 2 diabetes mellitus after acute myocardial infarction: results from the DIAMOND prospective cohort registry

Author

Won, Ki‑Bum, Hur, Seung‑Ho, Cho, Yun‑Kyeong, Yoon, Hyuck‑Jun, Nam, Chang‑Wook, Kim, Kwon‑Bae, Bae, Jang‑Ho, Choi, Dong‑Ju, Ahn, Young‑Keun, Park, Jong‑Seon, Kim, Hyo‑Soo, Choi, Rak‑Kyeong, Choi, Donghoon, Kim, Joon‑Hong, Han, Kyoo‑Rok, Park, Hun‑Sik, Choi, So‑Yeon, Yoon, Jung‑Han, Kwon, Hyeon‑Cheol, Rha, Seung-Woon, Hwang, Kyung‑Kuk, Lim, Do‑Sun, Jung, Kyung‑Tae, Oh, Seok‑Kyu, Lee, Jae‑Hwan, Shin, Eun‑Seok, and Kim, Kee‑Sik

Published
2023
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7. Metformin treatment is associated with improved survival in diabetic patients hospitalized with acute heart failure: A prospective observational study using the Korean acute heart failure registry data

Author

Chun, Kyeong-Hyeon, Oh, Jaewon, Lee, Chan Joo, Park, Jin Joo, Lee, Sang Eun, Kim, Min-Seok, Cho, Hyun-Jai, Choi, Jin-Oh, Lee, Hae-Young, Hwang, Kyung-Kuk, Kim, Kye Hun, Yoo, Byung-Su, Choi, Dong-Ju, Baek, Sang Hong, Jeon, Eun-Seok, Kim, Jae-Joong, Cho, Myeong-Chan, Chae, Shung Chull, Oh, Byung-Hee, and Kang, Seok-Min

Published
2024
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8. Beta-blockers after percutaneous coronary intervention for acute myocardial infarction and non-reduced left ventricular ejection fraction.

Author

Jeong, Jun-Chang, Park, Jong-Il, Kim, Byung-Jun, Kim, Hong-Ju, Choi, Kang-Un, Nam, Jong-Ho, Lee, Chan-Hee, Son, Jang-Won, Park, Jong-Seon, Her, Sung-Ho, Chang, Ki-Yuk, Ahn, Tae-Hoon, Jeong, Myung-Ho, Rha, Seung-Woon, Kim, Hyo-Soo, Gwon, Hyeon-Cheol, Seong, In-Whan, Hwang, Kyung-Kuk, Hur, Seung-Ho, and Cha, Kwang-Soo

Published
2024
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10. Clinical Implication of ‘Obesity Paradox’ in Elderly Patients With Acute Myocardial Infarction

Author

Kim, Hun-Tae, Jung, Sung-Yun, Nam, Jong-Ho, Lee, Jung-Hee, Lee, Chan-Hee, Son, Jang-Won, Kim, Ung, Park, Jong-Seon, Shin, Dong-Gu, Her, Sung-Ho, Chang, Ki-yuk, Ahn, Tae-Hoon, Jeong, Myung-Ho, Rha, Seung-Woon, Kim, Hyo-Soo, Gwon, Hyeon-Cheol, Seong, In-Whan, Hwang, Kyung-Kuk, Chae, Sung-Chull, Kim, Kwon-Bae, Cha, Kwang-Soo, Oh, Seok-Kyu, and Chae, Jei-Keon

Published
2021
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11. Risk prediction for 30-day heart failure-specific readmission or death after discharge: Data from the Korean Acute Heart Failure (KorAHF) registry

Author

Lim, Nam-Kyoo, Lee, Sang Eun, Lee, Hae-Young, Cho, Hyun-Jai, Choe, Won-Seok, Kim, Hokon, Choi, Jin Oh, Jeon, Eun-Seok, Kim, Min-Seok, Kim, Jae-Joong, Hwang, Kyung-Kuk, Chae, Shung Chull, Baek, Sang Hong, Kang, Seok-Min, Choi, Dong-Ju, Yoo, Byung-Su, Kim, Kye Hun, Cho, Myeong-Chan, Oh, Byung-Hee, and Park, Hyun-Young

Published
2019
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12. Lower Atrial Fibrillation Risk With Sodium-Glucose Cotransporter 2 Inhibitors Than With Dipeptidyl Peptidase-4 Inhibitors in Individuals With Type 2 Diabetes: A Nationwide Cohort Study

Author

Kim, Min, primary, Ha, Kyoung Hwa, additional, Lee, Junyoung, additional, Park, Sangshin, additional, Oh, Kyeong Seok, additional, Bae, Dae-Hwan, additional, Lee, Ju Hee, additional, Kim, Sang Min, additional, Choi, Woong Gil, additional, Hwang, Kyung-Kuk, additional, Kim, Dong-Woon, additional, MD, Myeong-Chan Cho, additional, Kim, Dae Jung, additional, and MD, Jang-Whan Bae, additional

Published
2024
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13. Outcomes After Predischarge Initiation of β-Blocker in Patients Hospitalized for Severe Decompensated Heart Failure Requiring Inotropic Therapy

Author

Cho, Min Soo, Kim, Min-Seok, Lee, Sang Eun, Choi, Hyo-In, Lee, Jung-Bok, Cho, Hyun-Jai, Lee, Hae-Young, Choi, Jin-Oh, Jeon, Eun-Seok, Hwang, Kyung-Kuk, Chae, Shung Chul, Baek, Sang Hong, Kang, Seok-Min, Choi, Dong-Ju, Yoo, Byung-Su, Ahn, Youngkeun, Kim, Kye-Hoon, Park, Hyun-Young, Cho, Myeong-Chan, Oh, Byung-Hee, and Kim, Jae-Joong

Published
2018
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14. Effect of renin-angiotensin system blockade in patients with severe renal insufficiency and heart failure

Author

Jang, Se Yong, Chae, Shung Chull, Bae, Myung Hwan, Lee, Jang Hoon, Yang, Dong Heon, Park, Hun Sik, Cho, Yongkeun, Cho, Hyun-Jai, Lee, Hae-Young, Oh, Byung-Hee, Choi, Jin-Oh, Jeon, Eun-Seok, Kim, Min-Seok, Lee, Sang Eun, Kim, Jae-Joong, Hwang, Kyung-Kuk, Cho, Myeong-Chan, Baek, Sang Hong, Kang, Seok-Min, Choi, Dong-Ju, Yoo, Byung-Su, Ahn, Youngkeun, Kim, Kye Hun, and Park, Hyun-Young

Published
2018
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15. Optimal Timing of Percutaneous Coronary Intervention in Patients With Non–ST-Segment Elevation Myocardial Infarction Complicated by Acute Decompensated Heart Failure (from the Korea Acute Myocardial Infarction Registry-National Institutes of Health [KAMIR-NIH])

Author

Kim, Min Chul, Jeong, Myung Ho, Sim, Doo Sun, Hong, Young Joon, Kim, Ju Han, Ahn, Youngkeun, Ahn, Tae Hoon, Seung, Ki Bae, Choi, Dong-Joo, Kim, Hyo-Soo, Gwon, Hyeon Cheol, Seong, In Whan, Hwang, Kyung Kuk, Chae, Shung Chull, Hur, Seung Ho, Cha, Kwang Soo, Oh, Seok Kyu, and Chae, Jei Keon

Published
2018
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16. Effects of angiotensin receptor blocker at discharge in patients with heart failure with reduced ejection fraction: Korean Acute Heart Failure (KorAHF) registry

Author

Choi, Ki Hong, Lee, Ga Yeon, Choi, Jin-Oh, Jeon, Eun-Seok, Lee, Hae-Young, Cho, Hyun-Jai, Lee, Sang Eun, Kim, Min-Seok, Kim, Jae-Joong, Hwang, Kyung-Kuk, Chae, Shung Chull, Baek, Sang Hong, Kang, Seok-Min, Choi, Dong-Ju, Yoo, Byung-Su, Kim, Kye Hun, Park, Hyun-Young, Cho, Myeong-Chan, and Oh, Byung-Hee

Published
2018
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17. Inhibition of Coxsackievirus-associated dystrophin cleavage prevents cardiomyopathy

Author

Lim, Byung-Kwan, Peter, Angela K, Xiong, Dingding, Narezkina, Anna, Yung, Aaron, Dalton, Nancy D, Hwang, Kyung-Kuk, Yajima, Toshitaka, Chen, Ju, and Knowlton, Kirk U

Subjects
Medical Microbiology, Medical Physiology, Biomedical and Clinical Sciences, Pediatric, Prevention, Cardiovascular, Heart Disease, Rare Diseases, Infectious Diseases, 2.1 Biological and endogenous factors, Animals, Cells, Cultured, Coxsackievirus Infections, Cysteine Endopeptidases, Cytopathogenic Effect, Viral, Dystrophin, Enterovirus B, Human, Gene Knock-In Techniques, Male, Mice, Mice, Inbred C3H, Mutation, Myocarditis, Myocytes, Cardiac, Proteolysis, Recombinant Fusion Proteins, Sarcolemma, Transgenes, Viral Proteins, Virus Replication, Medical and Health Sciences, Immunology, Biological sciences, Biomedical and clinical sciences, Health sciences
Abstract

Heart failure in children and adults is often the consequence of myocarditis associated with Coxsackievirus (CV) infection. Upon CV infection, enteroviral protease 2A cleaves a small number of host proteins including dystrophin, which links actin filaments to the plasma membrane of muscle fiber cells (sarcolemma). It is unknown whether protease 2A-mediated cleavage of dystrophin and subsequent disruption of the sarcolemma play a role in CV-mediated myocarditis. We generated knockin mice harboring a mutation at the protease 2A cleavage site of the dystrophin gene, which prevents dystrophin cleavage following CV infection. Compared with wild-type mice, we found that mice expressing cleavage-resistant dystrophin had a decrease in sarcolemmal disruption and cardiac virus titer following CV infection. In addition, cleavage-resistant dystrophin inhibited the cardiomyopathy induced by cardiomyocyte-restricted expression of the CV protease 2A transgene. These findings indicate that protease 2A-mediated cleavage of dystrophin is critical for viral propagation, enteroviral-mediated cytopathic effects, and the development of cardiomyopathy.

Published
2013

19. Changes in alcohol consumption habits and risk of atrial fibrillation: a nationwide population-based study

Author

Leea, Jae-woo, primary, Roh, Seung-Young, additional, Yoon, Woong-Su, additional, Kim, Jinseob, additional, Jo, Eunseo, additional, Bae, Dae-Hwan, additional, Kim, Min, additional, Lee, Ju-Hee, additional, Kim, Sang Min, additional, Choi, Woong Gil, additional, Bae, Jang-Whan, additional, Hwang, Kyung-Kuk, additional, Kim, Dong-Woon, additional, Cho, Myeong-Chan, additional, Kim, Ye-Seul, additional, Kim, Yonghwan, additional, You, Hyo-Sun, additional, Kan, Hee-Taik, additional, and Lee, Dae-In, additional

Published
2023
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22. Comparison of short-term clinical outcomes between ticagrelor versus clopidogrel in patients with acute myocardial infarction undergoing successful revascularization; from Korea Acute Myocardial Infarction Registry—National Institute of Health

Author

Park, Keun-Ho, Jeong, Myung Ho, Ahn, Youngkeun, Ahn, Tae Hoon, Seung, Ki Bae, Oh, Dong Joo, Choi, Dong-Joo, Kim, Hyo-Soo, Gwon, Hyeon Cheol, Seong, In Whan, Hwang, Kyung Kuk, Chae, Shung Chull, Kim, Kwon-Bae, Kim, Young Jo, Cha, Kwang Soo, Oh, Seok Kyu, and Chae, Jei Keon

Published
2016
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24. Additional file 5 of In-hospital glycemic variability and all-cause mortality among patients hospitalized for acute heart failure

Author

Chun, Kyeong-Hyeon, Oh, Jaewon, Lee, Chan Joo, Park, Jin Joo, Lee, Sang Eun, Kim, Min-Seok, Cho, Hyun-Jai, Choi, Jin-Oh, Lee, Hae-Young, Hwang, Kyung-Kuk, Kim, Kye Hun, Yoo, Byung-Su, Choi, Dong-Ju, Baek, Sang Hong, Jeon, Eun-Seok, Kim, Jae-Joong, Cho, Myeong-Chan, Chae, Shung Chull, Oh, Byung-Hee, and Kang, Seok-Min

Abstract

Additional file 5: Fig. S4. Spline curves for the hazard ratio of 1-year all-cause mortality according to glucose variability. Glycemic variability was presented by (A) standard deviation (SD) of serum glucose levels and (B) coefficient of variation (CoV) of serum glucose levels.

Published
2023
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25. Additional file 2 of In-hospital glycemic variability and all-cause mortality among patients hospitalized for acute heart failure

Author

Chun, Kyeong-Hyeon, Oh, Jaewon, Lee, Chan Joo, Park, Jin Joo, Lee, Sang Eun, Kim, Min-Seok, Cho, Hyun-Jai, Choi, Jin-Oh, Lee, Hae-Young, Hwang, Kyung-Kuk, Kim, Kye Hun, Yoo, Byung-Su, Choi, Dong-Ju, Baek, Sang Hong, Jeon, Eun-Seok, Kim, Jae-Joong, Cho, Myeong-Chan, Chae, Shung Chull, Oh, Byung-Hee, and Kang, Seok-Min

Abstract

Additional file 2: Fig. S1. Scatter plot of the blood glucose level of all subjects (at the time of admission, minimum, maximum values during hospitalization, and at discharge, respectively).

Published
2023
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26. Additional file 4 of In-hospital glycemic variability and all-cause mortality among patients hospitalized for acute heart failure

Author

Chun, Kyeong-Hyeon, Oh, Jaewon, Lee, Chan Joo, Park, Jin Joo, Lee, Sang Eun, Kim, Min-Seok, Cho, Hyun-Jai, Choi, Jin-Oh, Lee, Hae-Young, Hwang, Kyung-Kuk, Kim, Kye Hun, Yoo, Byung-Su, Choi, Dong-Ju, Baek, Sang Hong, Jeon, Eun-Seok, Kim, Jae-Joong, Cho, Myeong-Chan, Chae, Shung Chull, Oh, Byung-Hee, and Kang, Seok-Min

Abstract

Additional file 4: Fig. S3. Scatter plots of the blood glucose level of the subjects (at the time of admission, minimum, maximum values during hospitalization, and at discharge, respectively) according to the use of insulin during hospitalization were presented. The plot on the left is a plot of patients who used insulin, and the plot on the right is a plot of patients who did not use insulin.

Published
2023
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27. Additional file 1 of In-hospital glycemic variability and all-cause mortality among patients hospitalized for acute heart failure

Author

Chun, Kyeong-Hyeon, Oh, Jaewon, Lee, Chan Joo, Park, Jin Joo, Lee, Sang Eun, Kim, Min-Seok, Cho, Hyun-Jai, Choi, Jin-Oh, Lee, Hae-Young, Hwang, Kyung-Kuk, Kim, Kye Hun, Yoo, Byung-Su, Choi, Dong-Ju, Baek, Sang Hong, Jeon, Eun-Seok, Kim, Jae-Joong, Cho, Myeong-Chan, Chae, Shung Chull, Oh, Byung-Hee, and Kang, Seok-Min

Abstract

Additional file 1: Additional Tables.

Published
2023
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28. Additional file 3 of In-hospital glycemic variability and all-cause mortality among patients hospitalized for acute heart failure

Author

Chun, Kyeong-Hyeon, Oh, Jaewon, Lee, Chan Joo, Park, Jin Joo, Lee, Sang Eun, Kim, Min-Seok, Cho, Hyun-Jai, Choi, Jin-Oh, Lee, Hae-Young, Hwang, Kyung-Kuk, Kim, Kye Hun, Yoo, Byung-Su, Choi, Dong-Ju, Baek, Sang Hong, Jeon, Eun-Seok, Kim, Jae-Joong, Cho, Myeong-Chan, Chae, Shung Chull, Oh, Byung-Hee, and Kang, Seok-Min

Abstract

Additional file 3: Fig. S2. Scatter plots of the blood glucose level of the subjects (at the time of admission, minimum, maximum values during hospitalization, and at discharge, respectively) according to the presence of diabetes were presented. The plot on the left is for diabetic patients, and the plot on the right is for non-diabetic patients.

Published
2023
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30. Three-Year Clinical Outcomes of a Thin-Strut Biodegradable-Polymer Everolimus-Eluting Stent in Patients With Acute Coronary Syndrome

Author

Sim, Doo Sun, primary, Hyun, Dae Young, additional, Cho, Kyung Hoon, additional, Kim, Min Chul, additional, Hong, Young Joon, additional, Kim, Ju Han, additional, Ahn, Youngkeun, additional, Jeong, Myung Ho, additional, Chun, Kook Jin, additional, Ahn, Tae Hoon, additional, Jeong, Young Hoon, additional, Hwang, Kyung Kuk, additional, Lee, Han Cheol, additional, Park, Keun Ho, additional, Hwang, Jin Yong, additional, Lee, Seung Uk, additional, Cho, Yun Kyeong, additional, Park, Jong Seon, additional, Kim, Doo Il, additional, Man Cho, Jin, additional, Cho, Jang Hyun, additional, Kim, Hee Yeol, additional, Hwang, Byung Hee, additional, Kim, Sang Hyun, additional, Yoon, Myeong Ho, additional, Heo, Jung Ho, additional, Kim, Soo Joong, additional, Joo, Seung Jae, additional, and Bae, Jang Ho, additional

Published
2023
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32. Secular trends and determinants of influenza vaccination uptake among patients with cardiovascular disease in Korea: Analysis using a nationwide database

Author

Kim, Min, primary, Yang, Bumhee, additional, Gu, Seonhye, additional, Kim, Eung-Gook, additional, Kim, So Rae, additional, Oh, Kyeong Seok, additional, Yoon, Woong-Su, additional, Bae, Dae-Hwan, additional, Lee, Ju Hee, additional, Kim, Sang Min, additional, Choi, Woong Gil, additional, Bae, Jang-Whan, additional, Hwang, Kyung-Kuk, additional, Kim, Dong-Woon, additional, Cho, Myeong-Chan, additional, Lee, Hyun, additional, and Lee, Dae-In, additional

Published
2022
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33. Adjunctive Cilostazol Versus Double-Dose Clopidogrel After Drug-Eluting Stent Implantation: The HOST-ASSURE Randomized Trial (Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis–Safety & Effectiveness of Drug-Eluting Stents & Anti-platelet Regimen)

Author

Park, Kyung Woo, Kang, Si-Hyuck, Park, Jin Joo, Yang, Han-Mo, Kang, Hyun-Jae, Koo, Bon-Kwon, Park, Byoung-Eun, Cha, Kwang Soo, Rhew, Jay Young, Jeon, Hui-Kyoung, Shin, Eun Seok, Oh, Ju Hyeon, Jeong, Myung-Ho, Kim, Sanghyun, Hwang, Kyung-Kuk, Yoon, Jung-Han, Lee, Sung Yun, Park, Tae-Ho, Moon, Keon Woong, Kwon, Hyuck-Moon, Chae, In-Ho, and Kim, Hyo-Soo

Published
2013
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36. The impact of angiotensin-converting-enzyme inhibitors versus angiotensin receptor blockers on 3-year clinical outcomes in elderly (≥ 65) patients with acute myocardial infarction without hypertension.

Author

Ahn, Woo Jin, Rha, Seung-Woon, Choi, Byoung Geol, Jeong, Myung Ho, Ahn, Tae Hoon, Yoon, Junghan, Kim, Hyo‐Soo, Seung, Ki‐Bae, Gwon, Hyeon‐Cheol, Chae, Shung Chull, Kim, Chong‐Jin, Cha, Kwang Soo, Lee, Jung‐Hee, Chae, Jei Keon, Joo, Seung‐Jae, Yoon, Chang‐Hwan, Hur, Seung‐Ho, Seong, In‐Whan, Hwang, Kyung‐Kuk, and Kim, Doo‐Il

Subjects
ANGIOTENSIN-receptor blockers, MYOCARDIAL infarction, MAJOR adverse cardiovascular events, OLDER patients, PERCUTANEOUS coronary intervention, OLDER people
Abstract

Objective: This study aimed to investigate the impact of angiotensin-converting-enzyme inhibitors (ACEI) and angiotensin II type 1 receptor blockers (ARB) on 3-year clinical outcomes in elderly (≥ 65) acute myocardial infarction (AMI) patients without a history of hypertension who underwent successful percutaneous coronary intervention (PCI) with drug-eluting stents (DES). Methods: A total of 13,104 AMI patients who were registered in the Korea AMI registry (KAMIR)-National Institutes of Health (NIH) were included in the study. The primary endpoint was 3-year major adverse cardiac events (MACE), which was defined as the composite of all-cause death, recurrent myocardial infarction (MI), and any repeat revascularization. To adjust baseline potential confounders, an inverse probability weighting (IPTW) analysis was performed. Results: The patients were divided into two groups: the ACEI group, n = 872 patients and the ARB group, n = 508 patients. After IPTW matching, baseline characteristics were balanced. During the 3-year clinical follow-up, the incidence of MACE was not different between the two groups. However, incidence of stroke (hazard ratio [HR], 0.375; 95% confidence interval [CI], 0.166–0.846; p = 0.018) and re-hospitalization due to heart failure (HF) (HR, 0.528; 95% CI, 0.289–0.965; p = 0.038) in the ACEI group were significantly lower than in the ARB group. Conclusion: In elderly AMI patients who underwent PCI with DES without a history of hypertension, the use of ACEI was significantly associated with reduced incidences of stroke, and re-hospitalization due to HF than those with the use of ARB. [ABSTRACT FROM AUTHOR]

Published
2023
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37. Impact of multivessel versus single-vessel disease on the association between low diastolic blood pressure and mortality after acute myocardial infarction with revascularization

Author

Kim, Min, primary, Bae, Dae-Hwan, additional, Lee, Ju Hee, additional, Lee, Dae In, additional, Kim, Sang Min, additional, Lee, Sang Yeub, additional, Bae, Jang-Whan, additional, Kim, Dong-Woon, additional, Cho, Myeong-Chan, additional, Hwang, Jin Yong, additional, Oh, Seok Kyu, additional, Cha, Kwang Soo, additional, Choi, Cheol Ung, additional, Gwon, Hyeon Cheol, additional, Jeong, Myung Ho, additional, and Hwang, Kyung-Kuk, additional

Published
2022
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38. Modified reverse shock index predicts early outcomes of heart failure with reduced ejection fraction

Author

Oh, Gyu Chul, primary, An, Seokyung, additional, Lee, Hae‐Young, additional, Cho, Hyun‐Jai, additional, Jeon, Eun‐Seok, additional, Lee, Sang Eun, additional, Kim, Jae‐Joong, additional, Kang, Seok‐Min, additional, Hwang, Kyung‐Kuk, additional, Cho, Myeong‐Chan, additional, Chae, Shung Chull, additional, Choi, Dong‐Ju, additional, Yoo, Byung‐Su, additional, Kim, Kye Hun, additional, Park, Sue K., additional, and Baek, Sang Hong, additional

Published
2022
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39. Positive Effect of Air Purifier Intervention on Baroreflex Sensitivity and Biomarkers of Oxidative Stress in Patients with Coronary Artery Disease: A Randomized Crossover Intervention Trial

Author

Eom, Sang-Yong, primary, Kim, Aryun, additional, Lee, Ju-Hee, additional, Kim, Sang Min, additional, Lee, Sang-Yeub, additional, Hwang, Kyung-Kuk, additional, Lim, Hyun-Joung, additional, Cho, Myeong-Chan, additional, Kim, Yong-Dae, additional, Bae, Jang-Whan, additional, Kim, Jun Hyung, additional, and Lee, Dae-In, additional

Published
2022
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40. Impact of successful restoration of sinus rhythm in patients with atrial fibrillation and acute heart failure: Results from the Korean Acute Heart Failure registry

Author

Cho, Youngjin, primary, Oh, Il-Young, additional, Park, Jin Joo, additional, Oh, Byung-Hee, additional, Jeon, Eun-Seok, additional, Kim, Jae-Joong, additional, Hwang, Kyung-Kuk, additional, Cho, Myeong-Chan, additional, Chae, Shung Chull, additional, Baek, Sang Hong, additional, Kang, Seok-Min, additional, Yoo, Byung-Su, additional, Ahn, Youngkeun, additional, and Choi, Dong-Ju, additional

Published
2022
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42. Gender differences in clinical outcomes of acute myocardial infarction undergoing percutaneous coronary intervention: insights from the KAMIR-NIH Registry

Author

Lee, Myunhee, Kim, Dae-Won, Park, Mahn-Won, Lee, Kyusup, Chang, Kiyuk, Chung, Wook Sung, Ahn, Tae Hoon, Jeong, Myung Ho, Rha, Seung-Woon, Kim, Hyo-Soo, Gwon, Hyeon Cheol, Seong, In Whan, Hwang, Kyung Kuk, Chae, Shung Chull, Kim, Kwon-Bae, Kim, Young Jo, Cha, Kwang Soo, Oh, Seok Kyu, Chae, Jei Keon, Jung, Ji-Hoon, and on behalf of KAMIR-NIH registry investigators

Subjects
Gender difference, Asian population, cardiovascular diseases, Acute myocardial infarction, Research Article, Percutaneous coronary intervention
Abstract

Background There are numerous but conflicting data regarding gender differences in outcomes following percutaneous coronary intervention (PCI). Furthermore, gender differences in clinical outcomes with acute myocardial infarction (AMI) following PCI in Asian population remain uncertain because of the under-representation of Asian in previous trials. Methods A total of 13, 104 AMI patients from Korea Acute Myocardial Infarction Registry-National Institute of Health (KAMIR-NIH) between November 2011 and December 2015 were classified into male (n = 8021, 75.9%) and female (n = 2547, 24.1%). We compared the demographic, clinical and angiographic characteristics, 30-days and 1-year major adverse cardiac and cerebrovascular events (MACCE) in women with those in men after AMI by using propensity score (PS) matching. Results Compared with men, women were older, had more comorbidities and more often presented with non-ST segment elevation myocardial infarction (NSTEMI) and reduced left ventricular systolic function. Over the median follow-up of 363 days, gender differences in both 30-days and 1-year MACCE as well as thrombolysis in myocardial infarction minor bleeding risk were not observed in the PS matched population (30-days MACCE: 5.3% vs. 4.7%, log-rank P = 0.494, HR = 1.126, 95% CI: 0.800-1.585; 1-year MACCE: 9.3% vs. 9.0%, log-rank P = 0.803, HR = 1.032, 95% CI: 0.802-1.328; TIMI minor bleeding: 4.9% vs. 3.9%, log-rank P= 0.215, HR = 1.255, 95% CI: 0.869-1.814). Conclusions Among Korean AMI population undergoing contemporary PCI, women, as compared with men, had different clinical and angiographic characteristics but showed similar 30-days and 1-year clinical outcomes. The risk of bleeding after PCI was comparable between men and women during one-year follow up.

Published
2020

43. Prognostic Impact and Predictors of New-Onset Atrial Fibrillation in Heart Failure

Author

Choi, Hyo-In, primary, Lee, Sang Eun, additional, Kim, Min-Seok, additional, Lee, Hae-Young, additional, Cho, Hyun-Jai, additional, Choi, Jin Oh, additional, Jeon, Eun-Seok, additional, Hwang, Kyung-Kuk, additional, Chae, Shung Chull, additional, Baek, Sang Hong, additional, Kang, Seok-Min, additional, Choi, Dong-Ju, additional, Yoo, Byung-Su, additional, Kim, Kye Hun, additional, Cho, Myeong-Chan, additional, Oh, Byung-Hee, additional, and Kim, Jae-Joong, additional

Published
2022
Full Text
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44. Corrigendum: The Prescription Characteristics, Efficacy and Safety of Spironolactone in Real-World Patients With Acute Heart Failure Syndrome: A Prospective Nationwide Cohort Study

Author

Na, Soo Jin, primary, Youn, Jong-Chan, additional, Lee, Hye Sun, additional, Jeon, Soyoung, additional, Lee, Hae-Young, additional, Cho, Hyun-Jai, additional, Choi, Jin-Oh, additional, Jeon, Eun-Seok, additional, Lee, Sang Eun, additional, Kim, Min-Seok, additional, Kim, Jae-Joong, additional, Hwang, Kyung-Kuk, additional, Cho, Myeong-Chan, additional, Chae, Shung Chull, additional, Kang, Seok-Min, additional, Choi, Dong-Ju, additional, Yoo, Byung-Su, additional, Kim, Kye Hun, additional, Oh, Byung-Hee, additional, and Baek, Sang Hong, additional

Published
2022
Full Text
View/download PDF

45. The Prescription Characteristics, Efficacy and Safety of Spironolactone in Real-World Patients With Acute Heart Failure Syndrome: A Prospective Nationwide Cohort Study

Author

Na, Soo Jin, primary, Youn, Jong-Chan, additional, Lee, Hye Sun, additional, Jeon, Soyoung, additional, Lee, Hae-Young, additional, Cho, Hyun-Jai, additional, Choi, Jin-Oh, additional, Jeon, Eun-Seok, additional, Lee, Sang Eun, additional, Kim, Min-Seok, additional, Kim, Jae-Joong, additional, Hwang, Kyung-Kuk, additional, Cho, Myeong-Chan, additional, Chae, Shung Chull, additional, Kang, Seok-Min, additional, Choi, Dong-Ju, additional, Yoo, Byung-Su, additional, Kim, Kye Hoon, additional, Oh, Byung-Hee, additional, and Baek, Sang Hong, additional

Published
2022
Full Text
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46. Real‐world eligibility for vericiguat in decompensated heart failure with reduced ejection fraction

Author

Oh, Jaewon, primary, Lee, Chan Joo, additional, Park, Jin Joo, additional, Lee, Sang Eun, additional, Kim, Min‐Seok, additional, Cho, Hyun‐Jai, additional, Choi, Jin‐Oh, additional, Lee, Hae‐Young, additional, Hwang, Kyung‐Kuk, additional, Kim, Kye Hun, additional, Yoo, Byung‐Su, additional, Choi, Dong‐Ju, additional, Baek, Sang Hong, additional, Jeon, Eun‐Seok, additional, Kim, Jae‐Joong, additional, Cho, Myeong‐Chan, additional, Chae, Shung Chull, additional, Oh, Byung‐Hee, additional, and Kang, Seok‐Min, additional

Published
2022
Full Text
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48. A dose–response relationship of renin–angiotensin system blockers and beta-blockers in patients with acute heart failure syndrome: a nationwide prospective cohort study

Author

Kim, Kyung An, primary, Kim, Eui-Soon, additional, Youn, Jong-Chan, additional, Lee, Hye Sun, additional, Jeon, Soyoung, additional, Lee, Hae-Young, additional, Cho, Hyun-Jai, additional, Choi, Jin-Oh, additional, Jeon, Eun-Seok, additional, Lee, Sang Eun, additional, Kim, Min-Seok, additional, Kim, Jae-Joong, additional, Hwang, Kyung-Kuk, additional, Cho, Myeong-Chan, additional, Chae, Shung Chull, additional, Kang, Seok-Min, additional, Choi, Dong-Ju, additional, Yoo, Byung-Su, additional, Kim, Kye Hun, additional, Oh, Byung-Hee, additional, and Baek, Sang Hong, additional

Published
2022
Full Text
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