95 results on '"Hutson, P.H."'
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2. Effect of the β3 adrenoceptor agonist CL 316243 on hypothalamic 5-HT synthesis and suppression of REM sleep in the rat
3. The hypothermic effect of 5-CT in mice is mediated through the 5-HT 7 receptor
4. Reduced social interaction following 3,4-methylenedioxymethamphetamine is not associated with enhanced 5-HT 2C receptor responsivity
5. Effects on sleep stages and microarchitecture of caffeine and its combination with zolpidem or trazodone in healthy volunteers
6. Characterisation of the effects of caffeine on sleep in the rat: a potential model of sleep disruption
7. CNS Target Identification and Validation: Avoiding the Valley of Death or Naive Optimism?
8. EFFECT OF ADRENAL STIMULATION ON PLASMA AND BRAIN TRYPTOPHAN CONCENTRATIONS
9. P.1.g.074 Acquired binge-eating behaviour produces alterations in dopaminergic neurochemistry in the brains of rats
10. The selective phosphodiesterase 9 (PDE9) inhibitor PF-04447943 (6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) enhances synaptic plasticity and cognitive function in rodents
11. Validation of a translational caffeine-induced insomnia model in rats and human volunteers
12. Gaboxadol, a selective extrasynaptic GABAA agonist, does not generalise to other sleep-enhancing drugs: A rat drug discrimination study
13. Effect of the β3 adrenoceptor agonist CL 316243 on hypothalamic 5-HT synthesis and suppression of REM sleep in the rat
14. Behavioral and biochemical characterization of a mutant mouse strain lacking d-amino acid oxidase activity and its implications for schizophrenia
15. P.8.b.007 Gaboxadol does not generalise to other sleep-enhancing agents in drug discrimination in rats
16. Determination of guinea-pig cortical γ-secretase activity ex vivo following the systemic administration of a γ-secretase inhibitor
17. Genetic knockout and pharmacological blockade studies of the 5-HT7 receptor suggest therapeutic potential in depression
18. P.2.25 Characterisation of a caffeine-inducedmodel of insomnia in the rat
19. The hypothermic effect of 5-CT in mice is mediated through the 5-HT7 receptor
20. Activation of mesolimbic dopamine function by phencyclidine is enhanced by 5-HT2C/2B receptor antagonists: neurochemical and behavioural studies
21. Evidence for accelerated desensitisation of 5-HT2C receptors following combined treatment with fluoxetine and the 5-HT1A receptor antagonist, WAY 100,635, in the rat
22. Competitive and Glycine/NMDA Receptor Antagonists Attenuate Withdrawal-induced Behaviours and Increased Hippocampal Acetylcholine Efflux in Morphine-dependent Rats
23. Atypical neuroleptic profile in rodents of L-701,324, an antagonist at the glycine/NMDA receptor
24. Attenuation of stress induced cortical dopamine neurones by L-701,324, a selective glycine/NMDA antagonist is mediated via an interaction with GABAergic neurones
25. The behavioural and neurochemical profile of the putative dopamine D3 receptor agonist, (+)-PD 128907, in the rat
26. The effects of GR127935, a putative 5-HT1D receptor antagonist, on brain 5-HT metabolism, extracellular 5-HTT concentration and behaviour in the guinea pig
27. Piperidine-ether based hNK1 antagonists 2: Investigation of the effect of N-substitution
28. The anticonvulsant and behavioural profile of L-687,414, a partial agonist acting at the glycine modulatory site on the N-methyl-D-aspartate (NMDA) receptor complex
29. Modulation of cholinergically-mediated hypothermia in mice by galanin may involve ATP sensitive potassium channels
30. Effects of substance P and CGRP on rat striatal acetylcholine efflux, measured by microdialysis
31. The glycine/NMDA receptor antagonist, R-(+)-HA-966, blocks activation of the mesolimbic dopaminergic system induced by phencyclidine and dizocilpine (MK-801) in rodents
32. L-689,660, a novel cholinomimetic with functional selectivity for M1 and M3 muscarinic receptors
33. R-(+)-HA-966, a glycine/NMDA receptor antagonist, selectively blocks the activation of the mesolimbic dopamine system by amphetamine
34. The TRH analogue MK-771, increases acetylcholine release in hippocampus but not striatum of the conscious rat
35. Hypothermia induced by the putative 5-HT1A agonists LY165163 and 8-OH-DPAT is not prevented by 5-HT depletion
36. 8-OH-DPAT-induced hyperphagia: Its neural basis and possible therapeutic relevance
37. Hippocampal 5-HT synthesis and release in vivo is decreased by infusion of 8-OHDPAT into the nucleus raphe dorsalis
38. Preface
39. Pharmacological and biochemical analysis of feeding behaviour
40. Analgesia induced by brief footshock: blockade by fenfluramine and 5-methoxy-N, N-dimethyltryptamine and prevention of blockade by 5-HT antagonists
41. The role of 5-HTB receptors in the paraventricular nucleus of the hypothalamus in the control of feeding
42. Bilateral lesions of the striatum induced with 6-hydroxydopamine abolish apomorphine-induced yawning in rats
43. Neurochemical and behavioural evidence for mediation of the hyperphagic action of 8-OH-DPAT by 5-HT cell body autoreceptors
44. Effect of isoprenaline infusion on the distribution of tryptophan, tyrosine and isoleucine between brain and other tissues
45. Evidence that the hyperphagic response to 8-OH-DPAT is mediated by 5-HT1A receptors
46. Extracellular concentrations of aspartate and glutamate in rat neostriatum following chemical stimulation of frontal cortex
47. A reliable multichannel commutator for making electrical contact with conscious, freely moving rats
48. Concurrent determination of effects of p-chloroamphetamine on central extracellular 5-hydroxytryptamine concentration and behaviour
49. Enhancement of footshock-induced analgesia by spinal 5,7-dihydroxytryptamine lesions
50. Application of serial sampling of cerebrospinal fluid in pharmacodynamic studies with a drug active in the CNS: Heptabarbital concentrations at onset and offset of loss of righting reflex in rats
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