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4. Traumatismes du rein

Author

Freton, L., Pradere, B., Fiard, G., Chebbi, A., Caes, T., Hutin, M., Olivier, J., Ruggiero, M., Dominique, I., Millet, C., Bergerat, S., Panayatopoulos, P., Betari, R., Patard, P.-M., Szabla, N., Brichart, N., Sabourin, L., Guleryuz, K., Dariane, C., Lebacle, C., Rizk, J., Gryn, A., Madec, F.-X., Rod, X., Nouhaud, F.-X., Matillon, X., and Peyronnet, B.

Published
2019
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8. Impact of hospital volume on the outcomes of renal trauma management

Author

Baloche, P., primary, Szabla, N., additional, Freton, L., additional, Hutin, M., additional, Ruggiero, M., additional, Dominique, I., additional, Millet, C., additional, Bergerat, S., additional, Panayotopoulos, P., additional, Betari, R., additional, Matillon, X., additional, Chebbi, A., additional, Caes, T., additional, Patard, P-M., additional, Brichart, N., additional, Dariane, C., additional, Baboudjian, M., additional, Gondran-Tellier, B., additional, Lebacle, C., additional, Madec, F-X., additional, Nouhaud, F-X., additional, Rod, X., additional, Fiard, G., additional, Pradere, B., additional, and Peyronnet, B., additional

Published
2022
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10. The Management of Urothelial Bladder Carcinoma with Synchronous and Bilateral Urothelial Carcinoma of the Upper Tractus at Saint Clair Hospital, South of France.

Author

Olaru-Soare, F., Cecchi, M., Hutin, M., Diallo, D., Ségui, B., Ayuso, D., Sima, C., Rascu, S., and Jinga, C. V.

Subjects
TRANSURETHRAL resection of bladder, ISCHEMIC stroke, URINARY organs, TRANSITIONAL cell carcinoma, BLADDER, HYDRONEPHROSIS, BLADDER cancer
Abstract

Introduction and Objectives. Urothelial carcinomas can arise throughout the entire urinary tract, the urinary bladder being the predominant point of origin. Synchronous multifocal non-muscle invasive urothelial carcinomas of the bladder (UCB) are not a rare finding. Although rare, the incidence of concomitant bladder and upper urothelial tract tumors (UTUC) is 8-17% and mostly found in recurrences after initial treatment. The aim of this article is to share our individual experience regarding the case management of a patient with synchronous bilateral UTUC and UCB, at presentation, for a better understanding and optimization of future patient care. Materials and Methods. A late November 2022 evening, Mr. V.J.M, an 81-year-old male patient, is brought into our emergency room at the request of his general practitioner for suspicion of acute ischemic stroke. A kidney and bladder ultrasound (US) scan was performed, finding bilateral hydronephrosis and the presence of a tumor mass measuring almost 3 centimeters on the right lateral wall of the bladder. A non-contrast CT scan confirmed the bilateral hydronephrosis as well as the presence of an endo-ureteral tissue density mass at L4 level on the right side and another an endo-ureteral tissue density mass in regard to the iliac vessels on the left side, highly in favor of urothelial lesions Results. An urgent urine drainage was granted, the patient undergoing surgery for a bilateral retrograde stent insertion. A second intervention consisting in a transurethral resection of the bladder and bilateral rigid and flexible diagnostic ureteroscopy (URS) was performed. The histopathological examination reported a non-muscle invasive low-grade papillary urothelial carcinoma (NMIBC) for all the lesions of the upper tractus as well as the bladder lesion. The patient then underwent surgery allowing the laser vaporization of all urothelial masses and bilateral double J stents were left in place as to ensure good kidney drainage. Conclusions. Although the incidence of concomitant bladder and upper urothelial tract tumors is very rare, it is something that we may stumble upon in everyday clinical practice. The management of multifocal and synchronous locations is difficult, requiring a multidisciplinary approach with a meticulous preoperative and postoperative planning as to offer the most adapted treatment plan, where minimal invasive treatment might be offered in highly selected cases as this one. If radical invasive treatment cannot be proposed, a more rigorous follow-up may be useful as not to compromise the oncological results. [ABSTRACT FROM AUTHOR]

Published
2023

11. Étude multicentrique française de la mortalité à trente jours après un traumatisme rénal

Author

Baboudjian, M., primary, Lebacle, C., additional, Gondran-Tellier, B., additional, Panayatopoulos, P., additional, Hutin, M., additional, Olivier, J., additional, Ruggiero, M., additional, Dominique, I., additional, Millet, C., additional, Bergerat, S., additional, Freton, L., additional, Betari, R., additional, Matillon, X., additional, Chebbi, A., additional, Caes, T., additional, Patard, P., additional, Szabla, N., additional, Fiard, G., additional, Pradere, B., additional, and Peyronnet, B., additional

Published
2021
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12. Y a-t-il un effet centre dans la prise en charge des traumatismes du rein ?

Author

Baloche, P., primary, Szabla, N., additional, Freton, L., additional, Hutin, M., additional, Ruggiero, M., additional, Dominique, I., additional, Millet, C., additional, Bergerat, S., additional, Panayotopoulos, P., additional, Betari, R., additional, Matillon, X., additional, Chebbi, A., additional, Caes, T., additional, Patard, P., additional, Brichart, N., additional, Dariane, C., additional, Lebacle, C., additional, Gondran-Tellier, B., additional, Pradere, B., additional, and Peyronnet, B., additional

Published
2021
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17. 131 - Early mobilization is safe after renal trauma: A multicenter study

Author

Peyronnet, B., Olivier, J., Hutin, M., Ruggiero, M., Dominique, I., Freton, L., Millet, C., Bergerat, S., Panayatopoulos, P., Betari, R., Chebbi, A., Caes, T., Patard, P., Szabla, N., Brichart, N., Bohem, A., Sabourin, L., Guleryuz, K., Prudhomme, T., Dariane, C., Lebacle, C., Rizk, J., Gryn, A., Madec, F-X., Nouhaud, F-X., Rod, X., Fiard, G., and Pradere, B.

Published
2018
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18. A0973 - Impact of hospital volume on the outcomes of renal trauma management

Author

Baloche, P., Szabla, N., Freton, L., Hutin, M., Ruggiero, M., Dominique, I., Millet, C., Bergerat, S., Panayotopoulos, P., Betari, R., Matillon, X., Chebbi, A., Caes, T., Patard, P-M., Brichart, N., Dariane, C., Baboudjian, M., Gondran-Tellier, B., Lebacle, C., Madec, F-X., Nouhaud, F-X., Rod, X., Fiard, G., Pradere, B., and Peyronnet, B.

Published
2022
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19. Functional analysis of African Xanthomonas oryzae pv. oryzae TALomes reveals a new susceptibility gene in bacterial leaf blight of rice

Author

Tran, T. T., Perez-Quintero, A. L., Wonni, I., Carpenter, S. C. D., Yu, Y. H., Wang, L., Leach, J. E., Verdier, Valérie, Cunnac, Sébastien, Bogdanove, A. J., Koebnik, Ralf, Hutin, M., and Szurek, Boris

Subjects
urogenital system, food and beverages
Abstract

Most Xanthomonas species translocate Transcription Activator-Like (TAL) effectors into plant cells where they function like plant transcription factors via a programmable DNA-binding domain. Characterized strains of rice pathogenic X. oryzae pv. oryzae harbor 9-16 different tal effector genes, but the function of only a few of them has been decoded. Using sequencing of entire genomes, we first performed comparative analyses of the complete repertoires of TAL effectors, herein referred to as TALomes, in three Xoo strains forming an African genetic lineage different from Asian Xoo. A phylogenetic analysis of the three TALomes combined with in silico predictions of TAL effector targets showed that African Xoo TALomes are highly conserved, genetically distant from Asian ones, and closely related to TAL effectors from the bacterial leaf streak pathogen Xanthomonas oryzae pv. oryzicola (Xoc). Nine clusters of TAL effectors could be identified among the three TALomes, including three showing higher levels of variation in their repeat variable diresidues (RVDs). Detailed analyses of these groups revealed recombination events as a possible source of variation among TAL effector genes. Next, to address contribution to virulence, nine TAL effector genes from the Malian Xoo strain MAI1 and four allelic variants from the Burkinabe Xoo strain BAI3, thus representing most of the TAL effector diversity in African Xoo strains, were expressed in the TAL effector-deficient X. oryzae strain X11-5A for gain-of-function assays. Inoculation of the susceptible rice variety Azucena lead to the discovery of three TAL effectors promoting virulence, including two TAL effectors previously reported to target the susceptibility (S) gene OsSWEET14 and a novel major virulence contributor, TalB. RNA profiling experiments in rice and in silico prediction of EBEs were carried out to identify candidate targets of TalB, revealing OsTFX1, a bZIP transcription factor previously identified as a bacterial blight S gene, and OsERF#123, which encodes a subgroup IXc AP2/ERF transcription factor. Use of designer TAL effectors demonstrated that induction of either gene resulted in greater susceptibility to strain X11-5A. The induction of OsERF#123 by BAI3 Delta 1, a talB knockout derivative of BAI3, carrying these designer TAL effectors increased virulence of BAI3 Delta 1, validating OsERF#123 as a new, bacterial blight S gene.

Published
2018

20. Incidence et morbi-mortalité des tumeurs de la voie excrétrice du transplant après transplantation rénale : étude multicentrique française

Author

Hutin, M., primary, Thezenas, S., additional, Timsit, M.O., additional, Pettenati, C., additional, Gallon, J., additional, Karam, G., additional, Branchereau, J., additional, Heldhli, O., additional, Badet, L., additional, Matillon, X., additional, Salomon, L., additional, Cholley, I., additional, Bessede, T., additional, Neuzillet, Y., additional, Robert, G., additional, Bensadoun, H., additional, Allenet, C., additional, Cormier, L., additional, Schneider, A., additional, Leclercq, V., additional, Sallusto, F., additional, Descazeaud, A., additional, Peyronnet, B., additional, Hascoet, J., additional, Bouye, S., additional, Lechevallier, E., additional, Delaporte, V., additional, Lannes, F., additional, Boutin, J.M., additional, Berthelot, L.P., additional, Iborra, F., additional, and Thuret, R., additional

Published
2019
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21. Risk factors for death after renal trauma: Results of the French multicenter study TRAUMAFUF

Author

Lebacle, C., primary, Ruggiero, M., additional, Hutin, M., additional, Freton, L., additional, Olivier, J., additional, Dominique, I., additional, Millet, C., additional, Bergerat, S., additional, Panayotopoulos, P., additional, Betari, R., additional, Matillon, X., additional, Chebbi, A., additional, Patard, P-M., additional, Szabla, N., additional, Brichart, N., additional, Boehm, A., additional, Rizk, J., additional, Gryn, A., additional, Dariane, C., additional, Madec, F-X., additional, Nouhaud, F-X., additional, Pradere, B., additional, Fiard, G., additional, Peyronnet, B., additional, Caes, T., additional, Sabourin, L., additional, Guleryuz, K., additional, and Rod, X., additional

Published
2019
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22. [The Allium ureteral stent in the management of ureteral stenoses, a retrospective, multicenter study]

Author

Guandalino, M., Droupy, S., Ruffion, A., Fiard, G., Hutin, M., Poncet, D., Pereira, B., Paparel, P., Terrier, J.-E., CHU Clermont-Ferrand, Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Université de Montpellier (UM), Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), and CHU Grenoble

Subjects
Adult, Aged, 80 and over, Male, Stenosis, Sténose, Fistula, Ureteral stent, Constriction, Pathologic, Middle Aged, Prosthesis Design, [SDV.MHEP.UN]Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology, Uretère, Humans, Female, Stents, Stent urétéral, Ureter, Aged, Retrospective Studies, Ureteral Obstruction, Fistule
Abstract

International audience; OBJECTIVE:To evaluate the performance of the Allium ureteral stent in the management of patients initially treated with double J stents for the long-term treatment of stenoses.MATERIALS AND METHODS:We performed a retrospective multicenter study involving 36 patients who received 37 Allium ureteral stents (metallic 24 Fr) between September 2011 and January 2015 in one of three French teaching hospital centers. The mean age of the patients was 63.8 years (min-max: 33-88 years) and most were women (70%). Of these patients, 5.6% had ureteral fistulae and 94.4% stenoses. Mean stenosis length was 4.15cm (min-max: 0.5-12cm). All analyses were two-tailed with an alpha risk of 0.05. Statistical significance was set at P

Published
2017

23. Traumatisme rénal de bas grade et durée de séjour : vers une prise en charge ambulatoire ? Résultats de l’étude multicentrique traumAFUf avec analyse par score de propension

Author

Freton, L., primary, Scailteux, L., additional, Olivier, J., additional, Langouet, Q., additional, Ruggiero, M., additional, Dominique, I., additional, Millet, C., additional, Bergerat, S., additional, Panayotopoulos, P., additional, Lebacle, C., additional, Rizk, J., additional, Matillon, X., additional, Gryn, A., additional, Madec, F., additional, Nouhaud, F., additional, Rod, X., additional, Hutin, M., additional, Fiard, G., additional, Pradere, B., additional, and Peyronnet, B., additional

Published
2018
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24. Facteurs de associés au décès après traumatismes du rein : résultats de l’étude multicentrique nationale traumAFUf

Author

Lebacle, C., primary, Fiard, G., additional, Hutin, M., additional, Dominique, I., additional, Matillon, X., additional, Madec, F.-X., additional, Rod, X., additional, Bergerat, S., additional, Betari, R., additional, Freton, L., additional, Patard, P.-M., additional, Gryn, A., additional, Brichart, N., additional, Szabla, N., additional, Guleryuz, K., additional, Millet, C., additional, Sabourin, L., additional, Olivier, J., additional, Caes, T., additional, Rizk, J., additional, Chebbi, A., additional, Nouhaud, F.-X., additional, Ruggiero, M., additional, Panayatopoulos, P., additional, Langouet, Q., additional, Bohem, A., additional, Pradere, B., additional, Dariane, C., additional, and Peyronnet, B., additional

Published
2018
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25. Is systematic early drainage relevant to treat urinary tract rupture in non-penetrating renal trauma? Results from a multicenter study

Author

Chebbi, A., primary, Giwerc, A., additional, Peyronnet, B., additional, Freton, L., additional, Olivier, J., additional, Langouet, Q., additional, Ruggiero, M., additional, Dominique, I., additional, Millet, C., additional, Bergerat, S., additional, Panayotopoulos, P., additional, Betari, R., additional, Matillon, X., additional, Caes, T., additional, Patard, P.M., additional, Szabla, N., additional, Brichart, N., additional, Sabourin, L., additional, Guleryuz, K., additional, Dariane, C., additional, Lebacle, C., additional, Rizk, J., additional, Gryn, A., additional, Madec, F.X., additional, Hutin, M., additional, Pradere, B., additional, Pfister, C., additional, Fiard, G., additional, and Nouhaud, F.X., additional

Published
2018
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26. Early mobilization is safe after renal trauma: A multicenter study

Author

Peyronnet, B., primary, Olivier, J., additional, Hutin, M., additional, Ruggiero, M., additional, Dominique, I., additional, Freton, L., additional, Millet, C., additional, Bergerat, S., additional, Panayatopoulos, P., additional, Betari, R., additional, Chebbi, A., additional, Caes, T., additional, Patard, P., additional, Szabla, N., additional, Brichart, N., additional, Bohem, A., additional, Sabourin, L., additional, Guleryuz, K., additional, Prudhomme, T., additional, Dariane, C., additional, Lebacle, C., additional, Rizk, J., additional, Gryn, A., additional, Madec, F-X., additional, Nouhaud, F-X., additional, Rod, X., additional, Fiard, G., additional, and Pradere, B., additional

Published
2018
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27. Risk factors for failure of conservative management in blunt renal trauma: Results of a French national multicenter study (TRAUMAFUF)

Author

Caes, T., primary, Rizk, J., additional, Olivier, O., additional, Panayatopoulos, P., additional, Ruggiero, M., additional, Hutin, M., additional, Bergerat, S., additional, Betari, R., additional, Freton, L., additional, Langouet, Q., additional, Dominique, I., additional, Matillon, X., additional, Chebbi, A., additional, Patard, P.M., additional, Szabla, N., additional, Brichart, N., additional, Sabourin, L., additional, Guleryuz, K., additional, Bohem, A., additional, Millet, C., additional, Rod, X., additional, Lebacle, C., additional, Gryn, A., additional, Madec, F.X., additional, Nouhaud, F.X., additional, Pradere, B., additional, Dariane, C., additional, Fiard, G., additional, and Peyronnet, B., additional

Published
2018
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28. Early discharge in patients with low grade renal trauma: Results of the TRAUMAFUF multicentre study

Author

Freton, L., primary, Scailteux, L.M., additional, Olivier, J., additional, Langouet, Q., additional, Ruggiero, M., additional, Dominique, I., additional, Millet, C., additional, Bergerat, S., additional, Panayatopoulos, P., additional, Betari, R., additional, Matillon, X., additional, Chebbi, A., additional, Caes, T., additional, Patard, P.M., additional, Szabla, N., additional, Brichart, N., additional, Bohem, A., additional, Sabourin, L., additional, Guleryuz, K., additional, Dariane, C., additional, Lebacle, C., additional, Rizk, J., additional, Gryn, A., additional, Madec, F.X., additional, Nouhaud, F.X., additional, Rod, X., additional, Hutin, M., additional, Pradere, B., additional, Fiard, G., additional, and Peyronnet, B., additional

Published
2018
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29. Management of renal trauma between adult and pediatric population

Author

Patard, P.M., primary, Abbo, O., additional, Gryn, A., additional, Hutin, M., additional, Ruggiero, M., additional, Dominique, I., additional, Freton, L., additional, Millet, C., additional, Bergerat, S., additional, Panayatopoulos, P., additional, Betari, R., additional, Chebbi, A., additional, Caes, T., additional, Szabla, N., additional, Bohem, A., additional, Sabourin, L., additional, Guleryuz, K., additional, Dariane, C., additional, Lebacle, C., additional, Rizk, J., additional, Madec, F., additional, Nouhaud, F-X., additional, Rod, X., additional, Pradere, B., additional, Fiard, G., additional, and Peyronnet, B., additional

Published
2018
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32. Multifunctional hybrid Polyoxometalates for silicone gels with improved thermal and mechanical properties

Author

SARTORIO, Camillo, LAZZARA, Giuseppe, CATALDO, Sebastiano, MILIOTO, Stefana, PIGNATARO, Bruno Giuseppe, Husby Rosnes, M, Hutin, M, Yvon, C, Panarello, S, Patanè, S, Cronin, L, Sartorio, C, Husby Rosnes, M, Hutin, M, Yvon, C, Lazzara, G, Cataldo, S, Panarello, S, Patanè, S, Milioto, S, Cronin, L, and Pignataro, B

Subjects
Power Electronic, polyoxametalate, Siliconic gel, Nanocomposite materials
Published
2014

33. Facteurs de risque d’échec du traitement conservateur des traumatismes du rein : une étude multicentrique (TRAUMAFUF)

Author

Caës, T., primary, Rizk, J., additional, Olivier, J., additional, Hutin, M., additional, Bergerat, S., additional, Betari, R., additional, Freton, L., additional, Ruggiero, M., additional, Panayatopoulos, P., additional, Patard, P.M., additional, Dariane, C., additional, Fiard, G., additional, Peyronnet, B., additional, Pradere, B., additional, Nouhaud, F.-X., additional, Langouet, Q., additional, Dominique, I., additional, Matillon, X., additional, Chebbi, A., additional, Szabla, N., additional, Brichart, N., additional, Sabourin, L., additional, Guleryuz, K., additional, Bohem, A., additional, Millet, C., additional, Rod, X., additional, Lebacle, C., additional, Gryn, A., additional, and Madec, F.-X., additional

Published
2017
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34. Comparaison des caractéristiques et de la prise en charge des traumatismes rénaux entre la population adulte et pédiatrique

Author

Patard, P., primary, Abbo, O., additional, Gryn, A., additional, Bergerat, S., additional, Matillon, X., additional, Betari, R., additional, Ruggiero, M., additional, Dominique, I., additional, Freton, L., additional, Rod, X., additional, Dariane, C., additional, Lebacle, C., additional, Pradere, B., additional, Fiard, G., additional, Peyronnet, B., additional, Panayatopoulos, P., additional, Olivier, J., additional, Langouet, Q., additional, Millet, C., additional, Hutin, M., additional, Chebbi, A., additional, Caes, T., additional, Szabla, N., additional, Brichart, N., additional, Sabourin, L., additional, Guleryuz, K., additional, Rizk, J., additional, Madec, F.-X., additional, and Nouhaud, F.-X., additional

Published
2017
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35. Long-term complications after renal traumas: Results of a national multicentric study

Author

Dominique, I., primary, Matillon, X., additional, Dariane, C., additional, Lebacle, C., additional, Pradere, B., additional, Olivier, J., additional, Freton, L., additional, Langouet, Q., additional, Ruggiero, M., additional, Millet, C., additional, Bergerat, S., additional, Panayatopoulos, P., additional, Betari, R., additional, Chebbi, A., additional, Caes, T., additional, Patard, P.M., additional, Szabla, N., additional, Brichart, N., additional, Bohem, A., additional, Sabourin, L., additional, Guleryuz, K., additional, Rizk, J., additional, Gryn, A., additional, Madec, F.X., additional, Nouhaud, F.X., additional, Rod, X., additional, Hutin, M., additional, Fiard, G., additional, and Peyronnet, B., additional

Published
2017
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36. MorTAL Kombat : the story of defense against TAL effectors through loss-of-susceptibility [plus corrigendum]

Author

Hutin, M., Perez-Quintero, A. L., Lopez, C., and Szurek, Boris

Subjects
Xanthomonas, urogenital system, hubs, TAL effectors, fungi, plant disease susceptibility S genes, food and beverages, agricultural biotechnology, loss-of-function alleles
Abstract

Many plant-pathogenic xanthomonads rely on Transcription Activator-Like (TAL) effectors to colonize their host. This particular family of type Ill effectors functions as specific plant transcription factors via a programmable DNA-binding domain. Upon binding to the promoters of plant disease susceptibility genes in a sequence-specific manner, the expression of these host genes is induced. However, plants have evolved specific strategies to counter the action of TAL effectors and confer resistance. One mechanism is to avoid the binding of TAL effectors by mutations of their DNA binding sites, resulting in resistance by loss-of-susceptibility. This article reviews our current knowledge of the susceptibility hubs targeted by Xanthomonas TAL effectors, possible evolutionary scenarios for plants to combat the pathogen with loss-of-function alleles, and how this knowledge can be used overall to develop new pathogen-informed breeding strategies and improve crop resistance.

Published
2015

37. 1151 - Risk factors for death after renal trauma: Results of the French multicenter study TRAUMAFUF

Author

Lebacle, C., Ruggiero, M., Hutin, M., Freton, L., Olivier, J., Dominique, I., Millet, C., Bergerat, S., Panayotopoulos, P., Betari, R., Matillon, X., Chebbi, A., Patard, P-M., Szabla, N., Brichart, N., Boehm, A., Rizk, J., Gryn, A., Dariane, C., Madec, F-X., Nouhaud, F-X., Pradere, B., Fiard, G., Peyronnet, B., Caes, T., Sabourin, L., Guleryuz, K., and Rod, X.

Published
2019
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39. PT032 - Early discharge in patients with low grade renal trauma: Results of the TRAUMAFUF multicentre study

Author

Freton, L., Scailteux, L.M., Olivier, J., Langouet, Q., Ruggiero, M., Dominique, I., Millet, C., Bergerat, S., Panayatopoulos, P., Betari, R., Matillon, X., Chebbi, A., Caes, T., Patard, P.M., Szabla, N., Brichart, N., Bohem, A., Sabourin, L., Guleryuz, K., Dariane, C., Lebacle, C., Rizk, J., Gryn, A., Madec, F.X., Nouhaud, F.X., Rod, X., Hutin, M., Pradere, B., Fiard, G., and Peyronnet, B.

Published
2018
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40. 127 - Is systematic early drainage relevant to treat urinary tract rupture in non-penetrating renal trauma? Results from a multicenter study

Author

Chebbi, A., Giwerc, A., Peyronnet, B., Freton, L., Olivier, J., Langouet, Q., Ruggiero, M., Dominique, I., Millet, C., Bergerat, S., Panayotopoulos, P., Betari, R., Matillon, X., Caes, T., Patard, P.M., Szabla, N., Brichart, N., Sabourin, L., Guleryuz, K., Dariane, C., Lebacle, C., Rizk, J., Gryn, A., Madec, F.X., Hutin, M., Pradere, B., Pfister, C., Fiard, G., and Nouhaud, F.X.

Published
2018
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41. 129 - Risk factors for failure of conservative management in blunt renal trauma: Results of a French national multicenter study (TRAUMAFUF)

Author

Caes, T., Rizk, J., Olivier, O., Panayatopoulos, P., Ruggiero, M., Hutin, M., Bergerat, S., Betari, R., Freton, L., Langouet, Q., Dominique, I., Matillon, X., Chebbi, A., Patard, P.M., Szabla, N., Brichart, N., Sabourin, L., Guleryuz, K., Bohem, A., Millet, C., Rod, X., Lebacle, C., Gryn, A., Madec, F.X., Nouhaud, F.X., Pradere, B., Dariane, C., Fiard, G., and Peyronnet, B.

Published
2018
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42. 134 - Management of renal trauma between adult and pediatric population

Author

Patard, P.M., Abbo, O., Gryn, A., Hutin, M., Ruggiero, M., Dominique, I., Freton, L., Millet, C., Bergerat, S., Panayatopoulos, P., Betari, R., Chebbi, A., Caes, T., Szabla, N., Bohem, A., Sabourin, L., Guleryuz, K., Dariane, C., Lebacle, C., Rizk, J., Madec, F., Nouhaud, F-X., Rod, X., Pradere, B., Fiard, G., and Peyronnet, B.

Published
2018
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43. Five phylogenetically close rice SWEET genes confer TAL effector-mediated susceptibility to Xanthomonas oryzae pv. oryzae

Author

Streubel, J., Pesce, C., Hutin, M., Koebnik, Ralf, Boch, J., and Szurek, Boris

Subjects
type-III, virulence, designer TALE, effector, urogenital system, rice, TALE, OsSWEET, food and beverages, plant resistance, plant pathogen
Abstract

Bacterial plant-pathogenic Xanthomonas strains translocate transcription activator-like (TAL) effectors into plant cells to function as specific transcription factors. Only a few plant target genes of TAL effectors have been identified, so far. Three plant SWEET genes encoding putative sugar transporters are known to be induced by TAL effectors from rice-pathogenic Xanthomonas oryzae pv. oryzae (Xoo). We predict and validate that expression of OsSWEET14 is induced by a novel TAL effector, Tal5, from an African Xoo strain. Artificial TAL effectors (ArtTALs) were constructed to individually target 20 SWEET orthologs in rice. They were used as designer virulence factors to study which rice SWEET genes can support Xoo virulence. The Tal5 target box differs from those of the already known TAL effectors TalC, AvrXa7 and PthXo3, which also induce expression of OsSWEET14, suggesting evolutionary convergence on key targets. ArtTALs efficiently complemented an Xoo talC mutant, demonstrating that specific induction of OsSWEET14 is the key target of TalC. ArtTALs that specifically target individual members of the rice SWEET family revealed three known and two novel SWEET genes to support bacterial virulence. Our results demonstrate that five phylogenetically close SWEET proteins, which presumably act as sucrose transporters, can support Xoo virulence.

Published
2013

44. 682 - Long-term complications after renal traumas: Results of a national multicentric study

Author

Dominique, I., Matillon, X., Dariane, C., Lebacle, C., Pradere, B., Olivier, J., Freton, L., Langouet, Q., Ruggiero, M., Millet, C., Bergerat, S., Panayatopoulos, P., Betari, R., Chebbi, A., Caes, T., Patard, P.M., Szabla, N., Brichart, N., Bohem, A., Sabourin, L., Guleryuz, K., Rizk, J., Gryn, A., Madec, F.X., Nouhaud, F.X., Rod, X., Hutin, M., Fiard, G., and Peyronnet, B.

Published
2017
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49. Contribution of type III/TAL effectors to pathogenicity

Author

Boch, J., Boureau, T., Brin, C., Cunnac, S., David, P., Feng, J. X., Hajri, A., Hutin, M., Ralf Koebnik, Mo, W. L., Pesce, C., Poussier, S., Streubel, J., Szurek, B., Tang, J. L., Tang, W., Tran, T. T., Verdier, V., Wu, F., and Zhao, S.

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