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In nature, organisms are exposed to variable environmental conditions that impact their performance and fitness. Despite the ubiquity of environmental variability, substantial knowledge gaps in our understanding of organismal responses to nonconstant thermal regimes remain. In the present study, using zebrafish (Danio rerio) as a model organism, we applied geometric morphometric methods to examine how challenging but ecologically realistic diel thermal fluctuations experienced during different life stages influence adult body shape, size, and condition. Zebrafish were exposed to either thermal fluctuations (22–32°C) or a static optimal temperature (27°C) sharing the same thermal mean during an early period spanning embryonic and larval ontogeny (days 0–30), a later period spanning juvenile and adult ontogeny (days 31–210), or a combination of both. We found that body shape, size, and condition were affected by thermal variability, but these plasticity‐mediated changes were dependent on the timing of ontogenetic exposure. Notably, after experiencing fluctuating temperatures during early ontogeny, females displayed a deeper abdomen while males displayed an elongated caudal peduncle region. Moreover, males displayed beneficial acclimation of body condition under lifelong fluctuating temperature exposure, whereas females did not. The present study, using ecologically realistic thermal regimes, provides insight into the timing of environmental experiences that generate phenotypic variation in zebrafish. [ABSTRACT FROM AUTHOR]

The performance of the ultraviolet telescope (UVIT) on-board AstroSat is reported. The performance in orbit is also compared with estimates made from the calibrations done on the ground. The sensitivity is found to be within $$\sim $$ 15% of the estimates, and the spatial resolution in the NUV is found to exceed significantly the design value of $$1.8^{\prime \prime }$$ and it is marginally better in the FUV. Images obtained from UVIT are presented to illustrate the details revealed by the high spatial resolution. The potential of multi-band observations in the ultraviolet with high spatial resolution is illustrated by some results. [ABSTRACT FROM AUTHOR]

Background Early risk factors for poor child outcomes are well established, and some group parenting programmes have demonstrated good outcomes for children under 3 years of age. This randomized controlled trial evaluated the effectiveness of the Incredible Years® Toddler Parenting Programme with parents of 1-year-old and 2-year-old children recruited by staff in disadvantaged Flying Start areas across Wales. Methods Eighty-nine families with a child aged between 12 and 36 months at baseline participated in a pragmatic community-based trial of the programme in eight Flying Start areas. Outcomes were measured at baseline, 6 months and 12 months using measures of parental mental health, competence, child behaviour, child development, home environment and blinded-observation of parent-child interactions. Results Significant intervention group improvements were found in parental mental well-being and observed praise at 6 months. Significant improvements for the intervention group at 12 months included child development, home environment and parental depression. Conclusion The study provides preliminary evidence for programme attendance. [ABSTRACT FROM AUTHOR]

Central to an understanding of evolution in sea-ice characteristics in response to climate change is an understanding of sea-ice dynamics. In this study, we investigate regional differences in ice dynamics in the Beaufort Sea and High Arctic using high-frequency ice buoy (beacon) data deployed during the SEDNA and IPY-CFL field campaigns from spring 2007 to winter 2008. Examined in particular are scaling laws determined from absolute dispersion statistics. We create temporal scaling maps to determine whether distinct dynamical regimes can be identified with differing scaling properties. The results from this analysis provide an alternative characterization to changes in sea ice based on dynamics rather than concentration and thickness, and thus insight into, and improved understanding of, the connections between sea-ice drift and morphology. [ABSTRACT FROM AUTHOR]

Background Parental language is associated with children's later language development. Parenting programmes, based on social learning theory, enhance a range of parenting behaviours, yet there is limited evidence for their effect on parental language. Aim To assess the benefits of a behavioural-based parenting programme, which features components of language and communication, to enhance parental language. Method Parents of toddlers, aged 12 to 36 months, were recruited from eight Flying Start early intervention centres across Wales. Participants were randomised 2:1 either to a parenting programme ( n = 60) or to a wait-list control group ( n = 29). Researchers were blind to participant allocation throughout the trial. Fifteen-minute video-recorded observations of parents and children interacting during free-play, both at a pre-intervention and at 6-month follow-up, provided the data for the study. Five observed measures of parental language were assessed; quantity and variety, encouraging, critical, child-led and parent led interactions. Intervention The Incredible Years Parent- Toddler Programme ( IYPTP) is a 12-week group-based behavioural intervention that teaches effective relationship and behavioural management skills including social, emotional and persistence coaching to enable parents to better support their children's development. Results Of 89 dyads that completed pre-intervention assessments 81 (54 intervention and 27 control) met the criteria for the current study. Intention to treat analysis indicated that child-led language interactions significantly benefited from the intervention [regression coefficient ( B) = −1.44, 95% confidence intervals ( CI) = −2.59 to −0.29, P = 0.015, effect size ( ES) = 0.47] and a positive trend for encouraging language in favour of the intervention sample was evident. Per-protocol sample analysis replicated these findings with encouraging language reaching statistical significance ( B = 1.07, 95% CI = 0.11 to 2.03, P = 0.03, ES = 0.52). No further benefits were evident. Conclusions The IYPTP has limited evidence as an effective programme for enhancing some aspects of parental language. [ABSTRACT FROM AUTHOR]

Natural environmental change has produced countless opportunities for species to disperse into and persist in habitats where they previously did not exist. Introduction and stocking programmes have facilitated similar sorts of colonization opportunities across considerably greater geographical scales and often in much shorter periods of time. Even though the mechanism of colonization differs, the result can be the same: evolutionary change in the colonizing population in response to novel selection pressures. As a consequence, some human-mediated fish transfers have unintentionally yielded novel research opportunities to study how phenotypes and genes interact with their environment and affect ecological and evolutionary change. The primary purpose here is to explore how work, directly or indirectly involved with human-mediated transfers, has unintentionally yielded novel research and research opportunities in fish ecology and evolution. Insights have produced new knowledge or altered previously held perceptions on topics such as local adaptation, rate of evolutionary change, phenotypic plasticity, alternative reproductive strategies, population structure and colonization probability. Well-documented stocking programmes, especially in terms of history, numbers and original population sources, can provide highly fertile ground for generating further insights on the ecology and evolution of fishes and of the factors likely to influence the success of conservation-based, restoration programmes. [ABSTRACT FROM AUTHOR]

The UVIT telescopes are a payload package on the ISRO Astrosat observatory. They are co-aligned with three X-ray telescopes, and will operate simultaneously with them. The overall observatory is summarized, and details are given of the design, performance, and operation of the UVIT telescopes. These will offer close to arcsecond resolution over half-degree fields, simultaneously in FUV, NUV, and blue-visible bands. All bands have several filters and the UV bands have low-dispersion objective gratings. [ABSTRACT FROM AUTHOR]

Genetic variability in reaction norms reflects differences in the ability of individuals, populations and ultimately species to respond to environmental change. By increasing our understanding of how genotype × environment interactions influence evolution, studies of genetic variation in phenotypic plasticity serve to refine our capacity to predict how populations will respond to natural and anthropogenic environmental variability, including climate change. Given the extraordinary variability in morphology, behaviour and life history in salmonids, one might anticipate the research milieu on reaction norms in these fishes to be empirically rich and intellectually engaging. Here, I undertake a review of genetic variability in continuous and discontinuous (threshold) norms of reaction in salmonid fishes, as determined primarily (but not exclusively) by common-garden experiments. Although in its infancy from a numerical publication perspective, there is taxonomically broad evidence of genetic differentiation in continuous, threshold and bivariate reaction norms among individuals, families and populations (including inter-population hybrids and backcrosses) for traits as divergent as embryonic development, age and size at maturity, and gene expression. There is compelling inferential evidence that plasticity is heritable and that population differences in reaction norms can reflect adaptive responses, by natural selection, to local environments. As a stimulus for future work, a series of 20 research questions are identified that focus on reaction-norm variability, selection, costs and constraints, demographic and conservation consequences, and genetic markers and correlates of phenotypic plasticity. [ABSTRACT FROM AUTHOR]

the incidence of conduct disorder in young children is 10% in the general population and 37% among fostered children. Up to 40% of untreated children diagnosed with conduct disorder develop problems later in life including drug misuse, criminal and violent behaviour. There are more than 80 000 looked after children in the UK, with 5000 in Wales. Challenging child behaviour is the main reason for placement breakdown and has huge cost implications as challenging children cost up to 10 times more in service use than children without conduct disorder. The Incredible Years (IY) evidence-based parenting programme is an effective, low cost solution in improving child behaviour and social competence in 'conventional' families and thus has the potential to support foster carers in managing difficult behaviours. Our main aims were to establish: This was a 12-month trial platform study with 46 foster carers in three authorities in Wales. Carers were allocated 2:1 intervention to waiting-list control. Validated measures were used to assess 'parenting' competency, carers' depression levels, child behaviour and service use. Measures were administered at baseline and 6-month follow-up. Intervention carers received the programme between baseline and follow-up. Analyses showed a significant reduction in child problem behaviour and improvement in carers' depression levels for intervention families at follow-up, compared with control. Unexpectedly, there was a significant improvement in control carers' self-reported 'parenting' strategies. Special education was the greatest service cost for looked after children. Initial foster carer training could incorporate the IY programme to support carers in establishing positive relationships and managing difficult child behaviour. Programme participation may lead to reduced service use and improved placement stability. [ABSTRACT FROM AUTHOR]

Individual variability in the mating success of male Atlantic cod Gadus morhua was quantified within an aggregation ( n= 59) breeding undisturbed in a large (684 m3) mesocosm tank. Observational and morphometric data were examined to assess the degree to which this mating variation could be explained by aspects of morphology, condition and spawning behaviour. The number of ventral mounts initiated ( i.e. mating success) was highly variable; most mounts were initiated by a very small percentage of available males. The significant correlate of male mating success was mass of the sound producing musculature, i.e. drumming muscles. Neither body size, condition, pelvic and median fin morphology nor aggression influenced the number of ventral mounts initiated by a male. The present study suggests a possible link between sound production and mating success in Atlantic cod. [ABSTRACT FROM AUTHOR]

1. Growth rate is of considerable importance to the life histories of indeterminately growing organisms. Its determination of size at age can generate positive associations with several traits, although the rate at which size increases with time has been negatively linked with survival. Such a trade-off may not, however, be evident at growth rates considerably less than species-specific maxima, nor need links between growth and life history be similar for both sexes. 2. Based on a 5-year, mark–recapture study of an unexploited population of Brook Trout ( Salvelinus fontinalis) near the edge of the species’ range, I tested the null hypotheses that seasonal growth does not differ between sexes and that survival is independent of growth rate. Both hypotheses were rejected. 3. Faster growth by males during summer, and by females during winter, can be explained by seasonal differences, by sex, in the proportional allocation of energy to gonads and soma. 4. Survival increased with growth rate per se, independently of the latter's effects on size at age; survival among males appears more dependent on growth than that of females. 5. The results indicate that there can be fitness costs associated with slow growth, that these costs can differ between sexes, and that they may be exacerbated during periods of energetic stress. Trade-offs between growth and survival may depend on the behavioural and developmental contexts in which they are examined, need not be ubiquitous and may vary throughout a species’ geographical range. [ABSTRACT FROM AUTHOR]

Abstract To examine constraints on evolution of larger body size in two stunted populations of brook charr (Salvelinus fontinalis ) from a single river in Cape Race, Newfoundland, Canada, we measured viability selection acting on length-at-age traits, and estimated quantitative genetic parameters in situ (following reconstruction of pedigree information from microsatellite data). Furthermore we tested for phenotypic differentiation between the populations, and for association of high juvenile growth with early maturity that is predicted by life history theory. Within each population, selection differentials and estimates of heritabilities for length-at-age traits suggested that evolution of larger size is prevented by both selective and genetic constraints. Between the populations, phenotypic differentiation was found in length-at-age and age of maturation traits, whereas early maturation was associated with increased juvenile growth (relative to adult growth) both within and between populations. The results suggest an adaptive plastic response in age of maturation to juvenile growth rates that have a largely environmental basis of determination. [ABSTRACT FROM AUTHOR]

Polymorphism at five microsatellite genetic markers (genotyped n = 496) and mark-recapture tagging data (tagged n = 9813) were used to define the population structure of brook charr, Salvelinus fontinalis from the Indian Bay watershed, Newfoundland, Canada. Despite the absence of physical barriers to migration among lakes, both genetic and tagging data suggest that brook charr in each lake represent reproductively isolated populations. Exact tests comparing allele frequencies, θ (global value = 0·063), R st (global value = 0·052), individual assignment tests, and Nei's genetic distance provided congruent estimates of population subdivision in agreement with the tagging data (only 2·2% of recaptures were lake-to-lake). The genetic structure of the brook charr populations corresponded with the geographic structure of the drainage basin on a qualitative level, although linear distance over water was not significantly correlated with the tagging data or the genetic distance measures. The agreement between the tagging and the genetic data suggest that microsatellite markers can be useful tools for defining real biological units. The results also suggest that brook charr exhibit microgeographic population structure at the watershed scale, and that this is the scale at which conservation and management of this salmonid might best be implemented. [ABSTRACT FROM AUTHOR]

Twenty-four health visitors participated in a 12-week course in behavioural intervention methods for work with children with behavioural difficulties. Each health visitor identified a family with child behavioural problems and worked with this family while attending the weekly training sessions. The course was run in 1998/99 and in 2000/01 for 12 health visitors. The 1998/99 trainees established a control group by identifying a second family experiencing similar difficulties. These families received the standard service for the same duration as the course. After the course, all health visitors demonstrated a significant increase in knowledge of behavioural terminology and reported an increased practice of behavioural techniques. Significant improvements were seen in measures of child behaviour and maternal mental health for both groups of intervention families, compared with non-significant improvements in the control families. The course's success in giving health visitors the skills and practice to develop effective behavioural strategies in work with child behavioural problems is also discussed. [ABSTRACT FROM AUTHOR]

OBJECTIVES: National and state data on the health, social, and economic consequences of unintended pregnancy prompted Washington policy makers to identify strategies to reduce such pregnancies. Though not well known, emergency contraceptive pills (ECPs) are a safe and effective contraceptive method that can prevent pregnancy if taken within 72 hr after unprotected intercourse. A coalition conceived the idea of enabling pharmacists to prescribe ECPs directly to women through collaborative drug therapy agreements (CDTAs) with physicians. METHODS: Following a feasibility study, five agencies initiated a novel pilot project in western Washington. Key components included informing pharmacists about ECPs and CDTAs; developing tools, providing training, and developing systems to establish pharmacist/ prescriber collaborative agreements; conducting a public awareness campaign; evaluating the impact of the project; and disseminating the results. RESULTS: More than 1000 pharmacists received training in all aspects of providing ECPs and 140 pharmacies participated in the project, with more than 145 CDTA on file. In the 16 months of pharmacy service provision, 11,969 ECP prescriptions were provided, possibly preventing 700 or more unintended pregnancies. The media launch led to 200 broadcast stories and increased calls to the ECP Hotline from 116 to an average of 1160 per month. CONCLUSION: Enabling pharmacists to provide ECPs directly to women is a convenient delivery system for a time-limited therapy. It increases the chances that women will use the therapy effectively and connects women without a provider to a source of care. By increasing access to an effective contraceptive, this projects supports the Washington State goal of reducing unintended pregnancy. [ABSTRACT FROM AUTHOR]

The AstroSat satellite is designed for multi-wavelength astronomy for observations covering a spectral range from soft and hard X-rays to the ultra-violet. The Ultraviolet Imaging Telescope (UVIT) is the only non-X-ray telescope on AstroSat and it provides the long lever arm to the multi-wavelength observations. In addition to the simultaneous multi-wavelength studies in coordination with the X-ray telescopes on-board AstroSat, UVIT is used to study a large variety of objects with arcsecond-level spatial resolution. During the first year of observations, UVIT has obtained images in many filter bands in the wavelength range 130-300 nm over a field of ~28', which are being used to study a variety of hot stars, nebulae, stellar clusters and galaxies. [ABSTRACT FROM AUTHOR]

This work describes an experimental study which reviews the various techniques that can be used for determination of anisotropy fields in recording media. At the present time this topic is of considerable importance due to the need to understand the detailed mechanisms of magnetization reversal and the factors that control the switching field distribution in recording media. We have used a metal-particle-based tape material and have employed various magnetic techniques for the determination of the apparent anisotropy field, H[sub K]. The techniques included hysteresis loops measured in a direction transverse to the texture direction of the tapes, single-point detection in the successive derivatives of the magnetization with respect to the field, transverse susceptibility measurement, and the variation of the bulk coercivity with temperature. We find the temperature variation of coercivity produces values of H[sub K] far smaller than values determined by other methods due to orientation effects. General agreement is seen for the other techniques mentioned and results for samples with differing degrees of texture show that the apparent anisotropy field of the grains as measured by these techniques is influenced greatly by orientation effects. © 2000 American Institute of Physics. [ABSTRACT FROM AUTHOR]

Spiral galaxies undergo strong ram-pressure effects when they fall into the galaxy cluster potential. As a consequence, their gas is stripped to form extended tails within which star formation can happen, giving them the typical jellyfish appearance. The ultraviolet imaging observations of jellyfish galaxies provide an opportunity to understand ongoing star formation in the stripped tails. We report the ultraviolet observations of the jellyfish galaxies JW39, JO60, JO194 and compare with observations in optical continuum and Hα. We detect knots of star formation in the disc and tails of the galaxies and find that their UV and Hα flux are well correlated. The optical emission line ratio maps of these galaxies are used to identify for every region the emission mechanism, due to either star formation, LINER or a mix of the two phenomena. The star-forming regions in the emission line maps match very well with the regions having significant UV flux. The central regions of two galaxies (JW39, JO194) show a reduction in UV flux which coincides with composite or LINER regions in the emission line maps. The galaxies studied here demonstrate significant star formation in the stripped tails, suppressed star formation in the central regions and present a possible case of accelerated quenching happening in jellyfish galaxies. [ABSTRACT FROM AUTHOR]

Introduction Raman spectroscopy is a powerful analytical technique that can rapidly and accurately identify biochemical changes in cells that have become neoplastic. We aim to transfer this laboratory based technique to the bedside in order to identify high-grade dysplasia and early malignant change within Barrett's oesophagus. Here we demonstrate the feasibility of a novel fibre-optic Raman probe to map the pathology encountered in a resected human distal oesophagus. Methods A novel Raman probe designed to fit through the 2.8 mm instrument channel of a standard endoscope was used to map a distal oesophagus ex vivo. Following Ivor-Lewis oesophagectomy (with curative intent in patients with oesophageal adenocarcinoma), a reproducible mapping grid was placed over the distal oesophagus and Raman spectra were measured at specified grid positions using 1 and 5 s acquisition times (). A monochromatic 830 nm laser was used for excitation and a Renishaw system 100 spectrometer for the measurement of Raman spectra. PWE-093 Mapping of a distal oesophagus using a perspex grid for probe positioning Results Laboratory based Raman systems can delineate eight pathological groups in the distal oesophagus with sensitivities between 73% and 100%. To date we have measured 76 spectra from 3 oesophageal specimens using the novel endoscopic probe and data collection and analysis is currently on-going (). Histopathological diagnosis has been confirmed by expert pathologists following point biopsy at each grid position in order to correlate the Raman signal with the gold standard. Multivariate analysis will be used to extract subtle spectral features to evaluate the accuracy of the probe for delineating between pathological groups. PWE-093 Example mean Raman probe spectra measured on normal squamous, Barrett's and neoplastic oesophageal tissue Conclusion Further data collection (currently on-going) is needed to generate a robust classification algorithm in order to delineate between Barrett's metaplasia, low/high-grade dysplasia and cancer in the distal oesophagus. Preliminary spectra obtained using a novel endoscopic probe are consistent with laboratory data and suggest profound potential for in vivo endoscopic diagnosis using Raman spectroscopy. [ABSTRACT FROM PUBLISHER]

We investigated soil organic carbon (SOC) characteristics in three forests along a north-south transect in Sweden where these forest types cover about 69% of the landscape. There was variation in 14C ages, and the median ages ranged from about 25 to > 2500 cal BP in SOC. Although total SOC and nitrogen (N) contents decreased, stable carbon isotope and humification indices increased with depth. These progressive changes with depth and age were related to degradation. The δ13C values and specific biomarkers indicated that organic carbon was primarily from C3 plants. Biomarkers were effective in distinguishing OC input from specific sources (i.e. angiosperms, gymnosperms and grasses). A sharp decrease in biomarkers with depth indicated degradation of OC in the upper soil horizon, and limited contribution in the subsoil towards the stabilization of SOC. The sharp decrease in carbon stocks and 14C age in the soil OC pool with increasing soil depth, and quite large values for the percentage of modern carbon, suggested a decrease in SOC pools. Overall, these results showed that carbon sequestration in high latitude forests was small, and their role as potential carbon sinks needs to be reassessed. Highlights We studied soil organic carbon (SOC) characteristics in Swedish boreal and temperate forests., The decline of SOC with depth contributes little to carbon sequestration in deeper soil horizons., Soil degradation causes a decline in total carbon, nitrogen, alkanes and lignin with depth and age., The role of these forests as carbon sinks needs to be reassessed because of degradation of SOC. [ABSTRACT FROM AUTHOR]

The article presents the poem "Sweetheart," by J. Hutchings. First Line: He wonders why he always thinks of jail. Last Line:What's a woman worth in Cigarettes?

The article presents the poem "Hungry Men in Jungles," by J. Hutchings. First Line: There are hungry men in jungles; Last Line: and they won't be losing ever.

Aim Raman spectroscopy of human tissue can provide a unique biochemical 'fingerprint' that alters with disease progression. Light incident on tissue is scattered and may be altered in wavelength, which can be represented as a Raman spectrum. A confocal fibreoptic Raman probe designed to fit down the accessory channel of a colonoscope has been constructed. This in-vitro study evaluated the accuracy of pathological diagnosis in the colon using probe-based Raman spectroscopy. Method Biopsy samples were collected at colonoscopy, snap frozen and stored at −80°C. Raman spectra with 10-s and 1-s acquisition periods were measured with the probe tip in contact with the mucosal surface of thawed specimens. Mathematical modelling using principal component analysis followed by linear discriminant analysis was used to correlate Raman spectra with histopathological diagnoses. Results Three-hundred and seventy-five Raman spectra were measured from a total of 356 colon biopsies (81 of normal colon mucosa, 79 of hyperplastic polyps, 92 of adenomatous polyps, 64 of adenocarcinoma and 40 of ulcerative colitis) from 177 patients. Spectral classification accuracies comparing pathology pairs ranged from 72.1 to 95.9% for 10-s acquisitions and from 61.5 to 95.1% for 1-s acquisitions. For a three-group model of normal, adenomatous and adenocarcinoma tissue, accuracies were 74.1% for 10-s acquisitions and 63.5% for 1-s acquisitions. Conclusion The confocal Raman probe system can distinguish between different colorectal pathologies. The probe has potential to establish Raman spectroscopy as a clinical tool for instant diagnosis at colonoscopy. [ABSTRACT FROM AUTHOR]

There are distinct challenges implicit to the development of minimally invasive endoscopic surgery for the eradication of early neoplasia in Barrett's oesophagus. Endoscopic resection and ablation of high-grade dysplasia and mucosal cancer offer alternative therapeutic options to those unsuitable or unwilling to contemplate radical surgical excision. It may also become the treatment of choice in the future. Technological developments enable the instantaneous and non-invasive diagnosis of microscopic tissue abnormalities in vivo. This is made possible by improving the level of information that can be obtained from the tissue. As well as the two-dimensional surface morphology image, which the traditional endoscope can view, we have used new techniques to enable structure at depth, using Optical Coherence Tomography, to be imaged in high resolution. Other advances, using Raman spectroscopy, enable the early endoscopic detection of biochemical and molecular changes in tissue that precede any changes in morphology, thus enabling earlier diagnosis of tissue abnormalities. This King James IV lecture details our recent work, to develop advanced imaging for the diagnosis of malignancy and pre-malignancy. After detection endoscopic photodynamic therapy and endoscopic mucosal resection can provide eradication of mucosal neoplasia. Following photodynamic therapy there was complete eradication of all high-grade dysplasia and intramucosal carcinoma in 40 of 42 patients with a maximum endoscopic follow-up period of 72 months. Following endoscopic resection of 95 patients, the mean survival for intramucosal adenocarcinoma and high-grade dysplasia was 40.6 and 60.8 months respectively. [ABSTRACT FROM AUTHOR]

Multivariate morphometric analyses were used to examine variation in head, body, and fin shape between two sympatric morphotypes of Arctic char (Salvelinus alpinus (L., 1758)) from Lake Hazen, Ellesmere Island, Nunavut, Canada. Population structure of the Lake Hazen Arctic char was examined using five microsatellite loci. The 'small' morph was found to have a larger (primarily deeper) head, larger and more elongate fins, and a deeper lateral profile than the 'large' morph. The morphs also differed in allometric growth patterns. The large and small morphs do not appear to represent genetically distinct populations. The head morphology of the Lake Hazen small and large morphs exhibited similarities to benthic and pelagic morphs (respectively) from other lakes. We hypothesize that the large morph may be adapted to high-efficiency swimming and that the small morph may be adapted to low-efficiency, high-acceleration swimming. Such functional trade-offs are not uncommon among fish specializing in dispersed or mobile prey (fish and plankton) and benthic prey, respectively. The lack of apparent genetic differentiation between the morphs may suggest that the morphological differences result, to some extent, from phenotypic plasticity. Based on these results and previous analyses, it seems reasonable to conclude that Lake Hazen Arctic char represent a resource polymorphism. Des analyses morphométriques multidimensionnelles nous ont servi à étudier la variation de la forme de la tête, du corps et des nageoires chez deux morphotypes sympatriques de l'omble chevalier (Salvelinus alpinus (L., 1758)) du lac Hazen, île d'Ellesmere, Nunavut, Canada. Nous avons déterminé la structure de population des ombles chevaliers du lac Hazen par l'examen de cinq locus microsatellites. Le morphotype « petit » possède une tête plus grosse (surtout plus haute), des nageoires plus grandes et plus allongées et un profil latéral plus élevé que le morphotype « grand ». Les morphotypes diffèrent aussi par leurs patrons de croissance allométrique. Les morphotypes petit et grand ne semblent pas représenter des populations génétiquement distinctes. La morphologie de la tête des morphotypes petit et grand du lac Hazen rappelle les morphotypes (respectivement) benthique et pélagique décrits dans d'autres lacs. Nous émettons l'hypothèse selon laquelle le grand morphotype peut être adapté à la nage de grande efficacité et le petit morphotype l'est à la nage de faible efficacité, mais d'accélération rapide. De tels compromis fonctionnels ne sont pas rares chez les poissons qui se spécialisent respectivement pour les proies dispersées ou mobiles (poissons et plancton) et pour les proies benthiques. L'absence apparente de différenciation génétique entre les morphotypes peut laisser croire que les différences morphologiques proviennent, dans une certaine mesure, de la plasticité phénotypique. D'après nos résultats et des analyses antérieures, il semble raisonnable de conclure que les ombles chevaliers du lac Hazen présentent un polymorphisme basé sur les ressources. [ABSTRACT FROM AUTHOR]

Abstract: Background: Parent training (PT) is identified as the most effective intervention for the treatment of conduct disorder (CD). Intervention observational outcomes are often reported as summarised composite scores, providing an overview of overall construct change. Methods and aims: Parents of children aged 3–5 years identified ‘at risk’ of developing CD were randomly allocated to either PT intervention or waiting list control group. Parent and child behaviours were assessed before and after the intervention period. The current paper aims to establish which individual observed parenting categories change as a result of PT, and which specific observed leader categories predict these changes. Results: Controlling for baseline scores, ANCOVA demonstrated changes in parent praise and reflective behaviours as significant post-intervention. One-way ANOVAs demonstrated higher levels of leader praise and reflective behaviours resulted in greater change in parental praise and reflective behaviours respectively. Regression analyses indicated these leader behaviours predict positive change in parental praise and reflective behaviours for intervention families. Conclusions: Composite observational scores provide an account of behaviour constructs, whereas individual behaviour categories provide an insight into the core components of these constructs. The results suggest praise and reflection as key leader behaviours that influence the mechanisms of change in parenting behaviours as a result of PT. [Copyright &y& Elsevier]

The incidence and magnitude of multiple paternity were estimated for a natural, unmanipulated spawning population of Atlantic salmon Salmo salar. Egg nests were surveyed in the autumn and sub-samples were excavated the following spring. Parentage data derived from microsatellite DNA revealed an unexpectedly high level of multiple paternity. Within a single redd, females may mate with as many as 16 different males, including small mature male parr and large anadromous males. Multiple paternity was most pronounced in areas of highest redd density, corresponding with increased abundances of mature male parr. In addition, there was considerable variation in success among males, although this variability did not depend upon the number of males participating in spawning. This work underscores the value of undertaking genetic studies on the mating systems of fishes in unmanipulated, natural environments. [ABSTRACT FROM AUTHOR]

Teacher-pupil relationships do not solely impact children's academic development; they also influence emotional and behavioural development. Positive teacher-pupil relationships help reduce maladaptive behaviour while negative ones can lead to increased academic, social and behavioural difficulties. Identifying and measuring teacher-pupil relationship through classroom behaviours and interactions is therefore important as an index of classroom-based influences on child outcome. This article illustrates the development and testing of a classroom observation measure - the Teacher-Pupil Observation Tool (T-POT) - in a small-scale study of 12 teachers and 107 children in 12 reception classrooms. To assess validity and reliability, observed behaviours on the T-POT were correlated with each other (internal validity), and with teacher rated reports of classroom behaviour (discriminant and concurrent validity). Observer agreement was also assessed (inter-rater reliability). The T-POT showed promising psychometric properties in all cases. The T-POT is currently the main outcome measure in four funded evaluation studies in Gwynedd, North Wales, and an outcome measure in a funded evaluation study in Clondalkin, Ireland. These studies will further benefit the measure's validity and reliability and test the sensitivity of the T-POT in detecting change in teacher-pupil behaviour over time. [ABSTRACT FROM AUTHOR]

Teacher--pupil relationships do not solely impact children's academic development; they also influence emotional and behavioural development. Positive teacher-pupil relationships help reduce maladaptive behaviour while negative ones can lead to increased academic, social and behavioural difficulties. identifying and measuring teacher--pupil relationship through classroom behaviours and interactions is therefore important as an index of classroom-based influences on child outcome. This article illustrates the development and testing of a classroom observation measure - the Teacher-Pupil Observation Tool (T-POT) - in a small-scale study of 12 teachers and 107 children in 12 reception classrooms. To assess validity and reliability, observed behaviours on the T-POT were correlated with each other (internal validity), and with teacher rated reports of classroom behaviour (discriminant and concurrent validity). Observer agreement was also assessed (inter-rater reliability). The T-POT showed promising psychometric properties in all cases. The T-POT is currently the main outcome measure in four funded evaluation studies in Gwynedd, North Wales, and an outcome measure in a funded evaluation study in Clondalkin, Ireland. These studies will further benefit the measure's validity and reliability and test the sensitivity of the T-POT in detecting change in teacher-pupil behaviour over time. [ABSTRACT FROM AUTHOR]

This paper outlines the presentation, aetiology and treatment of attention deficit hyperactivity disorder (ADHD) in pre-school children. A review of current parenting training interventions demonstrates that there is good evidence for their efficacy in reducing symptoms of ADHD in pre-school children, and three interventions are evaluated: The new forest parent training programme (NFPP); the triple P--positive parenting programme and the incredible years parent training programme (IY). The evaluation of the NFPP provides strong evidence demonstrating its effectiveness for pre-school children with ADHD, while the efficacy of the Triple--P and the IY programme have, to date, only been demonstrated on children with conduct problems and co-morbid ADHD. It is suggested that parent training should be the first choice treatment for pre-school children presenting signs of ADHD, and medication introduced only for those children where parent training is not effective. Few moderators of outcome have been identified for these interventions, with the exception of parental ADHD. Barriers to intervention and implementation fidelity will need to be addressed to achieve high levels of attendance, completion and efficacy. The IY programme is a good model for addressing fidelity issues and for overcoming barriers to intervention. The future directions for parent training are also discussed. [ABSTRACT FROM AUTHOR]

Background Change in parenting skills, particularly increased positive parenting, has been identified as the key component of successful evidence-based parent training (PT), playing a causal role in subsequent child behaviour change for both prevention and treatment of Conduct Disorder. The amount of change in parenting skills observed after PT varies and may be accounted for by both the content of the programme and by the level of PT implementer process skills. Such variation in implementer skills is an important component in the assessment of treatment fidelity, itself an essential factor in successful intervention outcome. Aims To establish whether the Leader Observation Tool, a reliable and valid process skills fidelity measure, can predict change in parenting skills after attendance on the Incredible Years PT programme. Results Positive leader skills categories of the Leader Observation Tool significantly predicted change in both parent-reported and independently observed parenting skills behaviour, which in turn, predicted change in child behaviour outcome. Conclusions Delivering an intervention with a high level of treatment fidelity not only preserves the behaviour change mechanisms of the intervention, but can also predict parental behaviour change, which itself predicts child behaviour change as a result of treatment. [ABSTRACT FROM AUTHOR]

Background This study examined the long-term efficacy of the Incredible Years (IY) BASIC Parenting Programme delivered as a preventive intervention with parents of pre-school children who display signs of attention deficit hyperactivity disorder (ADHD) and conduct problems. Families were followed up after the completion of a controlled trial with 11 Sure Start areas in North and Mid-Wales and North West England. Methods Participants in the study were 50 pre-school children whose parents had received the intervention. Child ADHD symptoms were assessed at baseline, at follow-up one (6 months after baseline); at follow-up two (12 months after baseline); and at follow-up three (18 months after baseline). Families in the original waiting-list control group were not assessed after follow-up one as they had subsequently received the same intervention. Results The significant post-intervention improvements in child ADHD symptoms evident at follow-up one were maintained over time, as demonstrated by statistical and clinical stability of measures. No significant differences were found for ADHD symptoms across each follow-up, indicating that the gains made post intervention were maintained for at least 12 months, with 57% of the sample maintaining scores below the clinical cut-off on the Conners. Eighty-six, 58, and 30 per cent respectively had maintained at least a modest, large, or very large improvement in ADHD symptoms at follow-up three. Conclusions Findings from this study suggest that the IY psychosocial treatment programme is a valuable intervention in the longer term for many pre-school children displaying early signs of ADHD. [ABSTRACT FROM AUTHOR]

Background Despite recognition of the need to deliver evidence-based programmes in the field of mental health, there is little emphasis on implementing such programmes with fidelity. Attempts by programme developers to ensure adherence to their programmes include the development of training, manuals and content scales, but these alone may be insufficient to ensure fidelity in replication. Observational measures lend themselves as a potentially useful assessment of intervention outcomes, providing accurate and objective accounts of the intervention process. Aim To develop a reliable and valid observational treatment fidelity tool of process skills required to deliver the Incredible Years (IY) BASIC parenting programme effectively. Methods An objective observational fidelity measure was developed to assess adherence to the IY BASIC parenting programme protocol. Observations were conducted on 12 IY BASIC parenting programme groups, attended by parents of pre-school children displaying signs of early onset conduct disorder. Results The Leader Observation Tool (LOT) achieved high internal reliability and good code–recode and inter-rater reliability. Evidence of concurrent validity was also obtained. Conclusions Having demonstrated that the LOT is a reliable and valid measure of implementation fidelity, further research is necessary to examine the relationship between LOT scores and intervention outcome. [ABSTRACT FROM AUTHOR]

Background The efficacy of the Incredible Years (IY) Basic parent training (PT) programme for a community-based sample of families with pre-school children at risk of developing both conduct problems and attention deficit hyperactivity disorder (ADHD) was examined. Methods Pre-school children displaying signs of both early-onset conduct problems and ADHD were randomly allocated to either IY PT intervention, or to a waiting list (WL) control group. Child symptoms were assessed before and after the intervention. Results Post intervention, the intervention group was associated with significantly lower levels of parent-reported inattention and hyperactive/impulsive difficulties, even after controlling for post-intervention changes in child deviance. In addition, 52% of those in the intervention condition, compared with 21% in the control condition, displayed clinically reliable improvements post intervention, giving an absolute risk reduction of 31% and a number needed to treat of 3.23. Conclusions Findings from this study indicate that the IY PT programme is a valuable intervention for many pre-school children displaying early signs of ADHD. [ABSTRACT FROM AUTHOR]

The Andromeda galaxy (M31) has been observed with the UltraViolet Imaging Telescope (UVIT) instrument onboard the AstroSat Observatory. The M31 sky area was covered with 19 fields, in multiple UV filters per field, over the period of 2017 to 2019. The entire galaxy was observed in the FUV F148W filter, and more than half observed in the NUV filters. A new calibration and data processing is described which improves the astrometry and photometry of the UVIT data. The high spatial resolution of UVIT (∼ 1 arcsec) and new astrometry calibration (∼ 0.2 arcsec) allow identification of UVIT sources with stars, star clusters, X-ray sources, and other source types within M31 to a much better level than previously possible. We present new results from matching UVIT sources with stars measured as part of the Pan-chromatic Hubble Andromeda Treasury project in M31. [ABSTRACT FROM AUTHOR]

Over the last 5 years, UVIT has completed observations of more than 500 proposals with ∼ 800 unique pointings. In addition, regular planned monitoring observations have been made and from their analysis various key parameters related to in orbit performance of UVIT have been quantified. The sensitivities of the UV channels have remained steady indicating no effect of potential molecular contamination confirming the adequacy of all the protocols implemented for avoiding contamination. The quality of the PSF through the years confirms adequacy of thermal control measures. The early calibrations obtained during the Performance Verification (PV) phase have been further revised for more subtle effects. These include flat fields and detector distortions with greater precision. The operations of UVIT have also evolved through in orbit experience, e.g. tweaking of operational sequencing, protocol for recovery from bright object detection (BOD) shutdowns, parameters for BOD thresholds, etc. Finally, some effects of charged particle hits on electronics led to opimised strategy for regular resetting. The Near-UV channel was lost in one of such operations. All the above in-orbit experiences are presented here. [ABSTRACT FROM AUTHOR]

We present a dynamical study of the narrow-line regions in two nearby type 2 quasars (QSO2s). We construct dynamical models based on detailed photoionization models of the emission-line gas, including the effects of internal dust, to apply to observations of large-scale outflows from these active galactic nuclei (AGNs). We use Mrk 477 and Mrk 34 in order to test our models against recent Hubble Space Telescope (HST) Space Telescope Imaging Spectrograph (STIS) observations of [O  iii ] emission-line kinematics, since these AGNs possess more energetic outflows than found in Seyfert galaxies. We find that the outflows within 500 pc are consistent with radiative acceleration of dusty gas, however the outflows in Mrk 34 are significantly more extended and may not be directly accelerated by radiation. We characterize the properties of X-ray winds found from the expansion of [O  iii ]-emitting gas close to the black hole. We show that such winds possess the kinetic energy density to disturb [O  iii ] gas at ∼1.8 kpc, and have sufficient energy to entrain the [O  iii ] clouds at ∼1.2 kpc. Assuming that the X-ray wind possesses the same radial mass distribution as the [O  iii ] gas, we find that the peak kinetic luminosity for this wind is 2 per cent of Mrk 34's bolometric luminosity, which is in the 0.5–5 per cent range required by some models for efficient feedback. Our work shows that, although the kinetic luminosity as measured from [O  iii ]-emitting gas is frequently low, X-ray winds may provide more than one order of magnitude higher kinetic power. [ABSTRACT FROM AUTHOR]

We use Hubble Space Telescope /Space Telescope Imaging Spectrograph long-slit G430M and G750M spectra to analyse the extended [O  iii ] λ5007 emission in a sample of 12 nearby (z < 0.12) luminous (L bol > 1.6 × 1045 erg s−1) QSO2s. The purpose of the study is to determine the properties of the mass outflows of ionized gas and their role in active galactic nucleus feedback. We measure fluxes and velocities as functions of radial distances. Using cloudy models and ionizing luminosities derived from [O  iii ] λ5007, we are able to estimate the densities for the emission-line gas. From these results, we derive masses of [O  iii ]-emitting gas, mass outflow rates, kinetic energies, kinetic luminosities, momenta, and momentum flow rates as a function of radial distance for each of the targets. For the sample, masses are several times |$10^{3}$| – |$10^{7}\, {\rm M_{\odot }}$| and peak outflow rates are from 9.3 × 10−3 to |$10.3\, {\rm M_{\odot }}\, {\rm yr^{-1}}$|⁠. The peak kinetic luminosities are (3.4 × 10−8)–(4.9 × 10−4) of the bolometric luminosity, which does not approach the (5.0 × 10−3)–(5.0 × 10−2) range required by some models for efficient feedback. For Mrk 34, which has the largest kinetic luminosity of our sample, in order to produce efficient feedback there would have to be 10 times more [O  iii ]-emitting gas than that we detected at its position of maximum kinetic luminosity. Three targets show extended [O  iii ] emission, but compact outflow regions. This may be due to different mass profiles or different evolutionary histories. [ABSTRACT FROM AUTHOR]

We present our preliminary far-ultraviolet spectra of the Seyfert Mrk 533 obtained with FUSE. These are among the first FUV spectra of a purportedly edgeon Seyfert, and show narrow OVI emission as well as some evidence for intrinsic absorption. [ABSTRACT FROM AUTHOR]

Iteroparity is a bet-hedging strategy where individuals spread the risk of reproductive failure over time. The occurrence of iteroparity (i.e. proportion of repeat spawners in annual returns) varies among Atlantic salmon (Salmo salar) populations, yet information on its ecological importance is limited. We compiled multi-decadal time series on the spawning history composition of Atlantic salmon annual returns across ten populations of the northwest Atlantic and West Greenland mixed-stock fishery landings to: (i) describe spatio-temporal patterns of iteroparity at the continental scale; (ii) quantify the reproductive contributions of repeat spawners; and (iii) test the hypothesis that iteroparity acts as a population safeguard during periods of low recruitment through repeat spawners' contributions. Despite high variability in the representation of repeat spawners among populations and years (range: 0–24.7%; average: 5.0%), we identified broad-scale spatio-temporal shifts in iteroparity, with increases in mid-latitudinal and northern populations (from 3.1% to 7.6%) and declines in southern areas (from 4.1% to 2.7%), between the 1971–1992 and 1993–2017 periods. Our findings highlight the potential for increased prevalence of iteroparity when threats are mitigated (e.g. fishing pressure), with measurable benefits to population processes manifested by the high reproductive contributions of repeat spawners, especially in years of low maiden spawner abundance. [ABSTRACT FROM AUTHOR]

Context. Some post-merger galaxies are known to undergo a starburst phase that quickly depletes the gas reservoir and turns it into a red-sequence galaxy, though the details are still unclear. Aims. Here we explore the pattern of recent star formation in the central region of the post-merger galaxy NGC7252 using highresolution ultraviolet (UV) images from the UVIT on ASTROSAT. Methods. The UVIT images with 1.2 and 1.4 arcsec resolution in the FUV and NUV are used to construct a FUV-NUV colour map of the central region. Results. The FUV-NUV pixel colour map for this canonical post-merger galaxy reveals a blue circumnuclear ring of diameter ~1000 (3.2 kpc) with bluer patches located over the ring. Based on a comparison to single stellar population models, we show that the ring is comprised of stellar populations with ages ≲300 Myr, with embedded star-forming clumps of younger age (≲150Myr). Conclusions. The suppressed star formation in the central region, along with the recent finding of a large amount of ionised gas, leads us to speculate that this ring may be connected to past feedback from a central super-massive black hole that has ionised the hydrogen gas in the central ~400 ~1:3 kpc. [ABSTRACT FROM AUTHOR]