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8. Author Reply

Author

Moler-Zapata, Silvia, Hutchings, Andrew, O’Neill, Stephen, Silverwood, Richard J., and Grieve, Richard

Published
2024
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11. Clinical effectiveness and cost-effectiveness of emergency surgery for adult emergency hospital admissions with common acute gastrointestinal conditions: the ESORT study

Author

Grieve, Richard, primary, Hutchings, Andrew, additional, Moler Zapata, Silvia, additional, O’Neill, Stephen, additional, Lugo-Palacios, David G, additional, Silverwood, Richard, additional, Cromwell, David, additional, Kircheis, Tommaso, additional, Silver, Elizabeth, additional, Snowdon, Claire, additional, Charlton, Paul, additional, Bellingan, Geoff, additional, Moonesinghe, Ramani, additional, Keele, Luke, additional, Smart, Neil, additional, and Hinchliffe, Robert, additional

Published
2023
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14. 2022 American College of Rheumatology/EULAR classification criteria for Takayasu arteritis

Author

Grayson, Peter C, primary, Ponte, Cristina, additional, Suppiah, Ravi, additional, Robson, Joanna C, additional, Gribbons, Katherine Bates, additional, Judge, Andrew, additional, Craven, Anthea, additional, Khalid, Sara, additional, Hutchings, Andrew, additional, Danda, Debashish, additional, Luqmani, Raashid A, additional, Watts, Richard A, additional, and Merkel, Peter A, additional

Published
2022
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15. 2022 American College of Rheumatology/EULAR classification criteria for giant cell arteritis

Author

Ponte, Cristina, primary, Grayson, Peter C, additional, Robson, Joanna C, additional, Suppiah, Ravi, additional, Gribbons, Katherine Bates, additional, Judge, Andrew, additional, Craven, Anthea, additional, Khalid, Sara, additional, Hutchings, Andrew, additional, Watts, Richard A, additional, Merkel, Peter A, additional, and Luqmani, Raashid A, additional

Published
2022
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17. Tackling barriers to COVID-19 vaccine uptake in London: a mixed-methods evaluation.

Author

Halvorsrud, Kristoffer, Shand, Jenny, Weil, Leonora G, Hutchings, Andrew, Zuriaga, Ana, Satterthwaite, Dane, Yip, Jennifer L Y, Eshareturi, Cyril, Billett, Julie, Hepworth, Ann, Dodhia, Rakesh, Schwartz, Ellen C, Penniston, Rachel, Mordaunt, Emma, Bulmer, Sophie, Barratt, Helen, Illingworth, John, Inskip, Joanna, Bury, Fran, and Jenkins, Deborah

Subjects
ETHNIC groups, RESEARCH funding, VACCINATION, INTERVIEWING, COVID-19 vaccines, VACCINATION coverage, ATTITUDE (Psychology), THEMATIC analysis, RESEARCH methodology, VACCINE hesitancy, TRUST, HEALTH equity, COVID-19 pandemic, COVID-19, PSYCHOSOCIAL factors
Abstract

Background In response to the COVID-19 pandemic, the first vaccine was administered in December 2020 in England. However, vaccination uptake has historically been lower in London than in other English regions. Methods Mixed-methods: This comprised an analysis of cumulative percentage uptake across London between 8 December 2020 and 6 June 2021 by vaccine priority cohorts and ethnicity. We also undertook thematic analyses of uptake barriers, interventions to tackle these and key learning from a qualitative survey of 27 London local authority representatives, vaccine plans from London's five Integrated Care Systems and interviews with 38 London system representatives. Results Vaccine uptake was lower in Black ethnic (57–65% uptake) compared with the White British group (90% uptake). Trust was a critical issue, including mistrust in the vaccine itself and in authorities administering or promoting it. The balance between putative costs and benefits of vaccination created uptake barriers for zero-hour and shift workers. Intensive, targeted and 'hyper-local' initiatives, which sustained community relationships and were not constrained by administrative boundaries, helped tackle these barriers. Conclusions The success of the national vaccination programme depended on conceding local autonomy, investing in responsive and long-term partnerships to engender trust through in-depth understanding of communities' beliefs. [ABSTRACT FROM AUTHOR]

Published
2023
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19. Reply

Author

Grayson, Peter C., primary, Ponte, Cristina, additional, Robson, Joanna C., additional, Suppiah, Ravi, additional, Judge, Andrew, additional, Hutchings, Andrew, additional, Craven, Anthea, additional, Khalid, Sara, additional, Luqmani, Raashid A., additional, Watts, Richard A., additional, and Merkel, Peter A., additional

Published
2022
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20. Impact of the first wave of COVID-19 on outcomes following emergency admissions for common acute surgical conditions: analysis of a national database in England

Author

Hutchings, Andrew, primary, Moonesinghe, Ramani, additional, Moler Zapata, Silvia, additional, Cromwell, David, additional, Bellingan, Geoff, additional, Vohra, Ravinder, additional, Moug, Susan, additional, Smart, Neil, additional, Hinchliffe, Robert, additional, and Grieve, Richard, additional

Published
2022
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22. Mixed methods evaluation of the Getting it Right First Time programme in elective orthopaedic surgery in England: an analysis from the National Joint Registry and Hospital Episode Statistics

Author

Barratt, Helen, primary, Hutchings, Andrew, additional, Pizzo, Elena, additional, Aspinal, Fiona, additional, Jasim, Sarah, additional, Gafoor, Rafael, additional, Ledger, Jean, additional, Mehta, Raj, additional, Mason, James, additional, Martin, Peter, additional, Fulop, Naomi J, additional, Morris, Stephen, additional, and Raine, Rosalind, additional

Published
2022
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25. 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for eosinophilic granulomatosis with polyangiitis

Author

Grayson, Peter, Ponte, Cristina, Suppiah, Ravi, Robson, Joanna C., Craven, Anthea, Judge, Andrew, Khalid, Sara, Luqmani, Raashid, Watts, Richard, Merkel, Peter, Hutchings, Andrew, Grayson, Peter C., Luqmani, Raashid A., Merkel, Peter A., Gatenby, Paul, Watts, Richard A., Hill, Catherine, Ranganathan, Dwarakanathan, Kronbichler, Andreas, Blockmans, Daniel, Barra, Lillian, Carette, Simon, Pagnoux, Christian, Dhindsa, Navjot, Fifi-Mah, Aurore, Khalidi, Nader, Liang, Patrick, Milman, Nataliya, Pineau, Christian, Tian, Xinping, Wang, Guochun, Wang, Tian, Zhao, Ming hui, Tesar, Vladimir, Baslund, Bo, Hammam, Nevin, Shahin, Amira, Pirila, Laura, Putaala, Jukka, Hellmich, Bernhard, Henes, Jörg, Lamprecht, Peter, Neumann, Thomas, Schmidt, Wolfgang, Sunderkoetter, Cord, Szekanecz, Zoltan, Danda, Debashish, Das, Siddharth, Gupta, Rajiva, Rajasekhar, Liza, Dobashi, Hiroaki, Sharma, Aman, Wagh, Shrikant, Clarkson, Michael, Kawakami, Tamihiro, Kobayashi, Shigeto, Kono, Hajime, Makino, Hirofumi, Matsui, Kazuo, Muso, Eri, Suzuki, Kazuo, Ikeda, Kei, Takeuchi, Tsutomu, Tsukamoto, Tatsuo, Uchida, Shunya, Wada, Takashi, Yamada, Hidehiro, Yamagata, Kunihiro, Yumura, Wako, Lai, Kan Sow, Flores-Suarez, Luis Felipe, Hinojosa, Andrea, Rutgers, Bram, Tak, Paul Peter, Grainger, Rebecca, Quincey, Vicki, Stamp, Lisa, Besada, Emilio, Diamantopoulos, Andreas, Sznajd, Jan, Azevedo, Elsa, Geraldes, Ruth, Rodrigues, Miguel, Santos, Ernestina, Song, Yeong Wook, Moiseev, Sergey, Hocˇevar, Alojzija, Arimura, Yoshihiro, Cid, Maria Cinta, Moreno, Xavier Solanich, Atukorala, Inoshi, Berglin, Ewa, Molloy, Eamonn, Salvarani, Carlo, Schiavon, Franco, Tombetti, Enrico, Vaglio, Augusto, Amano, Koichi, Fujimoto, Shouichi, Harigai, Masayoshi, Hirano, Fumio, Hirahashi, Junichi, and Honma, Sakae

Abstract

Objective: To develop and validate revised classification criteria for eosinophilic granulomatosis with polyangiitis (EGPA). Methods: Patients with vasculitis or comparator diseases were recruited into an international cohort. The study proceeded in 5 phases: 1) identification of candidate criteria items using consensus methodology, 2) prospective collection of candidate items present at the time of diagnosis, 3) data-driven reduction of the number of candidate items, 4) expert panel review of cases to define the reference diagnosis, and 5) derivation of a points-based risk score for disease classification in a development set using least absolute shrinkage and selection operator logistic regression, with subsequent validation of performance characteristics in an independent set of cases and comparators. Results: The development set for EGPA consisted of 107 cases of EGPA and 450 comparators. The validation set consisted of an additional 119 cases of EGPA and 437 comparators. From 91 candidate items, regression analysis identified 11 items for EPGA, 7 of which were retained. The final criteria and their weights were as follows: maximum eosinophil count ≥1 × 109/liter (+5), obstructive airway disease (+3), nasal polyps (+3), cytoplasmic antineutrophil cytoplasmic antibody (ANCA) or anti–proteinase 3 ANCA positivity (−3), extravascular eosinophilic predominant inflammation (+2), mononeuritis multiplex/motor neuropathy not due to radiculopathy (+1), and hematuria (−1). After excluding mimics of vasculitis, a patient with a diagnosis of small- or medium-vessel vasculitis could be classified as having EGPA if the cumulative score was ≥6 points. When these criteria were tested in the validation data set, the sensitivity was 85% (95% confidence interval [95% CI] 77–91%) and the specificity was 99% (95% CI 98–100%). Conclusion: The 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for EGPA demonstrate strong performance characteristics and are validated for use in research.

Published
2022

27. Correction to: Tackling barriers to COVID-19 vaccine uptake in London: a mixed-methods evaluation

Author

Halvorsrud, Kristoffer, primary, Shand, Jenny, additional, Weil, Leonora G, additional, Hutchings, Andrew, additional, Zuriaga, Ana, additional, Satterthwaite, Dane, additional, Yip, Jennifer L Y, additional, Eshareturi, Cyril, additional, Billett, Julie, additional, Hepworth, Ann, additional, Dodhia, Rakesh, additional, Schwartz, Ellen C, additional, Penniston, Rachel, additional, Mordaunt, Emma, additional, Bulmer, Sophie, additional, Barratt, Helen, additional, Illingworth, John, additional, Inskip, Joanna, additional, Bury, Fran, additional, Jenkins, Deborah, additional, Mounier-Jack, Sandra, additional, and Raine, Rosalind, additional

Published
2022
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29. Tackling barriers to COVID-19 vaccine uptake in London: a mixed-methods evaluation

Author

Halvorsrud, Kristoffer, primary, Shand, Jenny, additional, Weil, Leonora G, additional, Hutchings, Andrew, additional, Zuriaga, Ana, additional, Satterthwaite, Dane, additional, Yip, Jennifer L Y, additional, Eshareturi, Cyril, additional, Billett, Julie, additional, Hepworth, Ann, additional, Dodhia, Rakesh, additional, Schwartz, Ellen C, additional, Penniston, Rachel, additional, Mordaunt, Emma, additional, Bulmer, Sophie, additional, Barratt, Helen, additional, Illingworth, John, additional, Inskip, Joanna, additional, Bury, Fran, additional, Jenkins, Deborah, additional, Mounier-Jack, Sandra, additional, and Raine, Rosalind, additional

Published
2022
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34. 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology Classification Criteria for Eosinophilic Granulomatosis with Polyangiitis

Author

Grayson, Peter C, primary, Ponte, Cristina, additional, Suppiah, Ravi, additional, Robson, Joanna C, additional, Craven, Anthea, additional, Judge, Andrew, additional, Khalid, Sara, additional, Hutchings, Andrew, additional, Luqmani, Raashid A, additional, Watts, Richard A, additional, and Merkel, Peter A, additional

Published
2022
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35. 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for microscopic polyangiitis

Author

Suppiah, Ravi, primary, Robson, Joanna C, additional, Grayson, Peter C, additional, Ponte, Cristina, additional, Craven, Anthea, additional, Khalid, Sara, additional, Judge, Andrew, additional, Hutchings, Andrew, additional, Merkel, Peter A, additional, Luqmani, Raashid A, additional, and Watts, Richard A, additional

Published
2022
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36. 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for granulomatosis with polyangiitis

Author

Robson, Joanna C, primary, Grayson, Peter C, additional, Ponte, Cristina, additional, Suppiah, Ravi, additional, Craven, Anthea, additional, Judge, Andrew, additional, Khalid, Sara, additional, Hutchings, Andrew, additional, Watts, Richard A, additional, Merkel, Peter A, additional, and Luqmani, Raashid A, additional

Published
2022
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40. 2022 American College of Rheumatology/EULAR Classification Criteria for Giant Cell Arteritis.

Author

Ponte, Cristina, Grayson, Peter C., Robson, Joanna C., Suppiah, Ravi, Gribbons, Katherine Bates, Judge, Andrew, Craven, Anthea, Khalid, Sara, Hutchings, Andrew, Watts, Richard A., Merkel, Peter A., Luqmani, Raashid A., Gatenby, Paul, Hill, Catherine, Ranganathan, Dwarakanathan, Kronbichler, Andreas, Blockmans, Daniel, Barra, Lillian, Carette, Simon, and Pagnoux, Christian

Subjects
TEMPORAL arteries, C-reactive protein, RESEARCH evaluation, BIOPSY, CONFIDENCE intervals, RESEARCH methodology, GIANT cell arteritis, SEVERITY of illness index, BLOOD sedimentation
Abstract

Objective: To develop and validate updated classification criteria for giant cell arteritis (GCA). Methods: Patients with vasculitis or comparator diseases were recruited into an international cohort. The study proceeded in 6 phases: 1) identification of candidate items, 2) prospective collection of candidate items present at the time of diagnosis, 3) expert panel review of cases, 4) data‐driven reduction of candidate items, 5) derivation of a points‐based risk classification score in a development data set, and 6) validation in an independent data set. Results: The development data set consisted of 518 cases of GCA and 536 comparators. The validation data set consisted of 238 cases of GCA and 213 comparators. Age ≥50 years at diagnosis was an absolute requirement for classification. The final criteria items and weights were as follows: positive temporal artery biopsy or temporal artery halo sign on ultrasound (+5); erythrocyte sedimentation rate ≥50 mm/hour or C‐reactive protein ≥10 mg/liter (+3); sudden visual loss (+3); morning stiffness in shoulders or neck, jaw or tongue claudication, new temporal headache, scalp tenderness, temporal artery abnormality on vascular examination, bilateral axillary involvement on imaging, and fluorodeoxyglucose–positron emission tomography activity throughout the aorta (+2 each). A patient could be classified as having GCA with a cumulative score of ≥6 points. When these criteria were tested in the validation data set, the model area under the curve was 0.91 (95% confidence interval [95% CI] 0.88–0.94) with a sensitivity of 87.0% (95% CI 82.0–91.0%) and specificity of 94.8% (95% CI 91.0–97.4%). Conclusion: The 2022 American College of Rheumatology/EULAR GCA classification criteria are now validated for use in clinical research. [ABSTRACT FROM AUTHOR]

Published
2022
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41. 2022 American College of Rheumatology/EULAR Classification Criteria for Takayasu Arteritis.

Author

Grayson, Peter C., Ponte, Cristina, Suppiah, Ravi, Robson, Joanna C., Gribbons, Katherine Bates, Judge, Andrew, Craven, Anthea, Khalid, Sara, Hutchings, Andrew, Danda, Debashish, Luqmani, Raashid A., Watts, Richard A., Merkel, Peter A., Gatenby, Paul, Hill, Catherine, Ranganathan, Dwarakanathan, Kronbichler, Andreas, Blockmans, Daniel, Barra, Lillian, and Carette, Simon

Subjects
BLOOD pressure, CONFIDENCE intervals, RHEUMATOLOGY, AGE distribution, ANGINA pectoris, TAKAYASU arteritis, DIAGNOSTIC imaging, SEX distribution, DESCRIPTIVE statistics, SENSITIVITY & specificity (Statistics), VASCULITIS, INTERMITTENT claudication, PULSE (Heart beat)
Abstract

Objective: To develop and validate new classification criteria for Takayasu arteritis (TAK). Methods: Patients with vasculitis or comparator diseases were recruited into an international cohort. The study proceeded in 6 phases: 1) identification of candidate criteria items, 2) collection of candidate items present at diagnosis, 3) expert panel review of cases, 4) data‐driven reduction of candidate items, 5) derivation of a points‐based classification score in a development data set, and 6) validation in an independent data set. Results: The development data set consisted of 316 cases of TAK and 323 comparators. The validation data set consisted of an additional 146 cases of TAK and 127 comparators. Age ≤60 years at diagnosis and imaging evidence of large‐vessel vasculitis were absolute requirements to classify a patient as having TAK. The final criteria items and weights were as follows: female sex (+1), angina (+2), limb claudication (+2), arterial bruit (+2), reduced upper extremity pulse (+2), reduced pulse or tenderness of a carotid artery (+2), blood pressure difference between arms of ≥20 mm Hg (+1), number of affected arterial territories (+1 to +3), paired artery involvement (+1), and abdominal aorta plus renal or mesenteric involvement (+3). A patient could be classified as having TAK with a cumulative score of ≥5 points. When these criteria were tested in the validation data set, the model area under the curve was 0.97 (95% confidence interval [95% CI] 0.94–0.99) with a sensitivity of 93.8% (95% CI 88.6–97.1%) and specificity of 99.2% (95% CI 96.7–100.0%). Conclusion: The 2022 American College of Rheumatology/EULAR classification criteria for TAK are now validated for use in research. [ABSTRACT FROM AUTHOR]

Published
2022
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48. 2015 Recommendations for the management of polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative

Author

Dejaco, Christian, Singh, Yogesh P, Perel, Pablo, Hutchings, Andrew, Camellino, Dario, Mackie, Sarah, Abril, Andy, Bachta, Artur, Balint, Peter, Barraclough, Kevin, Bianconi, Lina, Buttgereit, Frank, Carsons, Steven, Ching, Daniel, Cid, Maria, Cimmino, Marco, Diamantopoulos, Andreas, Docken, William, Duftner, Christina, Fashanu, Billy, Gilbert, Kate, Hildreth, Pamela, Hollywood, Jane, Jayne, David, Lima, Manuella, Maharaj, Ajesh, Mallen, Christian, Martinez-Taboada, Victor, Maz, Mehrdad, Merry, Steven, Miller, Jean, Mori, Shunsuke, Neill, Lorna, Nordborg, Elisabeth, Nott, Jennifer, Padbury, Hannah, Pease, Colin, Salvarani, Carlo, Schirmer, Michael, Schmidt, Wolfgang, Spiera, Robert, Tronnier, David, Wagner, Alexandre, Whitlock, Madeline, Matteson, Eric L, and Dasgupta, Bhaskar

Published
2015
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