79,404 results on '"Hurst, A"'
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2. Homer's Odyssey and the Near East (review)
- Author
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Hurst, André
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- 2022
- Full Text
- View/download PDF
3. Innovating Bolometers' Mounting: A Gravity-Based Approach
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The CUPID Collaboration, Alfonso, K., Armatol, A., Augier, C., Avignone III, F. T., Azzolini, O., Barabash, A. S., Bari, G., Barresi, A., Baudin, D., Bellini, F., Benato, G., Benussi, L., Berest, V., Beretta, M., Bettelli, M., Biassoni, M., Billard, J., Boffelli, F., Boldrini, V., Brandani, E. D., Brofferio, C., Bucci, C., Buchynska, M., Camilleri, J., Campani, A., Cao, J., Capelli, C., Capelli, S., Caracciolo, V., Cardani, L., Carniti, P., Casali, N., Celi, E., Chang, C., Chapellier, M., Chen, H., Chiesa, D., Cintas, D., Clemenza, M., Colantoni, I., Copello, S., Cremonesi, O., Creswick, R. J., D'Addabbo, A., Dafinei, I., Danevich, F. A., De Dominicis, F., De Jesus, M., de Marcillac, P., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dompè, V., Drobizhev, A., Dumoulin, L., Fantini, G., Idrissi, M. El, Faverzani, M., Ferri, E., Ferri, F., Ferroni, F., Figueroa-Feliciano, E., Formaggio, J., Franceschi, A., Fu, S., Fujikawa, B. K., Gascon, J., Ghislandi, S., Giachero, A., Girola, M., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Grant, C., Gras, P., Guillaumon, P. V., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Helis, D. L., Huang, H. Z., Hurst, M. T., Imbert, L., Juillard, A., Karapetrov, G., Keppel, G., Khalife, H., Kobychev, V. V., Kolomensky, Yu. G., Kowalski, R., Lattaud, H., Lefevre, M., Lisovenko, M., Liu, R., Liu, Y., Loaiza, P., Ma, L., Mancarella, F., Manenti, N., Mariani, A., Marini, L., Marnieros, S., Martinez, M., Maruyama, R. H., Mas, Ph., Mayer, D., Mazzitelli, G., Mazzola, E., Mei, Y., Moore, M. N., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nones, C., Norman, E. B., Novosad, V., Nutini, I., O'Donnell, T., Olivieri, E., Olmi, M., Oregui, B. T., Pagan, S., Pageot, M., Pagnanini, L., Pasciuto, D., Pattavina, L., Pavan, M., Penek, Ò., Peng, H., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Pochon, O., Poda, D. V., Polakovic, T., Polischuk, O. G., Pottebaum, E. G., Pozzi, S., Previtali, E., Puiu, A., Puranam, S., Quitadamo, S., Rappoldi, A., Raselli, G. L., Ressa, A., Rizzoli, R., Rosenfeld, C., Rosier, P., Rossella, M., Scarpaci, J. A., Schmidt, B., Serino, R., Shaikina, A., Shang, K., Sharma, V., Shlegel, V. N., Singh, V., Sisti, M., Slocum, P., Speller, D., Surukuchi, P. T., Taffarello, L., Tomassini, S., Tomei, C., Torres, A., Torres, J. A., Tozzi, D., Tretyak, V. I., Trotta, D., Velazquez, M., Vetter, K. J., Wagaarachchi, S. L., Wang, G., Wang, L., Wang, R., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Xie, F., Xue, M., Yang, J., Yefremenko, V., Umatov, V. I., Zarytskyy, M. M., Zhu, T., Zolotarova, A., and Zucchelli, S.
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Physics - Instrumentation and Detectors ,High Energy Physics - Experiment ,Nuclear Experiment - Abstract
Cryogenic calorimeters, also known as bolometers, are among the leading technologies for searching for rare events. The CUPID experiment is exploiting this technology to deploy a tonne-scale detector to search for neutrinoless double-beta decay of $^{100}$Mo. The CUPID collaboration proposed an innovative approach to assembling bolometers in a stacked configuration, held in position solely by gravity. This gravity-based assembly method is unprecedented in the field of bolometers and offers several advantages, including relaxed mechanical tolerances and simplified construction. To assess and optimize its performance, we constructed a medium-scale prototype hosting 28 Li$_2$MoO$_4$ crystals and 30 Ge light detectors, both operated as cryogenic calorimeters at the Laboratori Nazionali del Gran Sasso (Italy). Despite an unexpected excess of noise in the light detectors, the results of this test proved (i) a thermal stability better than $\pm$0.5 mK at 10 mK, (ii) a good energy resolution of Li$_2$MoO$_4$ bolometers, (6.6 $\pm$ 2.2) keV FWHM at 2615 keV, and (iii) a Li$_2$MoO$_4$ light yield measured by the closest light detector of 0.36 keV/MeV, sufficient to guarantee the particle identification requested by CUPID.
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- 2025
4. Lossy Neural Compression for Geospatial Analytics: A Review
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Gomes, Carlos, Wittmann, Isabelle, Robert, Damien, Jakubik, Johannes, Reichelt, Tim, Martone, Michele, Maurogiovanni, Stefano, Vinge, Rikard, Hurst, Jonas, Scheurer, Erik, Sedona, Rocco, Brunschwiler, Thomas, Kesselheim, Stefan, Batic, Matej, Stier, Philip, Wegner, Jan Dirk, Cavallaro, Gabriele, Pebesma, Edzer, Marszalek, Michael, Belenguer-Plomer, Miguel A, Adriko, Kennedy, Fraccaro, Paolo, Kienzler, Romeo, Briq, Rania, Benassou, Sabrina, Lazzarini, Michele, and Albrecht, Conrad M
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Electrical Engineering and Systems Science - Signal Processing ,Computer Science - Artificial Intelligence ,Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Machine Learning ,Physics - Geophysics - Abstract
Over the past decades, there has been an explosion in the amount of available Earth Observation (EO) data. The unprecedented coverage of the Earth's surface and atmosphere by satellite imagery has resulted in large volumes of data that must be transmitted to ground stations, stored in data centers, and distributed to end users. Modern Earth System Models (ESMs) face similar challenges, operating at high spatial and temporal resolutions, producing petabytes of data per simulated day. Data compression has gained relevance over the past decade, with neural compression (NC) emerging from deep learning and information theory, making EO data and ESM outputs ideal candidates due to their abundance of unlabeled data. In this review, we outline recent developments in NC applied to geospatial data. We introduce the fundamental concepts of NC including seminal works in its traditional applications to image and video compression domains with focus on lossy compression. We discuss the unique characteristics of EO and ESM data, contrasting them with "natural images", and explain the additional challenges and opportunities they present. Moreover, we review current applications of NC across various EO modalities and explore the limited efforts in ESM compression to date. The advent of self-supervised learning (SSL) and foundation models (FM) has advanced methods to efficiently distill representations from vast unlabeled data. We connect these developments to NC for EO, highlighting the similarities between the two fields and elaborate on the potential of transferring compressed feature representations for machine--to--machine communication. Based on insights drawn from this review, we devise future directions relevant to applications in EO and ESM., Comment: self-consistent review paper
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- 2025
5. CUPID, the CUORE Upgrade with Particle Identification
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The CUPID Collaboration, Alfonso, K., Armatol, A., Augier, C., Avignone III, F. T., Azzolini, O., Barabash, A. S., Bari, G., Barresi, A., Baudin, D., Bellini, F., Benato, G., Benussi, L., Berest, V., Beretta, M., Bettelli, M., Biassoni, M., Billard, J., Boffelli, F., Boldrini, V., Brandani, E. D., Brofferio, C., Bucci, C., Buchynska, M., Camilleri, J., Campani, A., Cao, J., Capelli, C., Capelli, S., Caracciolo, V., Cardani, L., Carniti, P., Casali, N., Celi, E., Chang, C., Chen, H., Chiesa, D., Cintas, D., Clemenza, M., Colantoni, I., Copello, S., Cremonesi, O., Creswick, R. J., D'Addabbo, A., Dafinei, I., Danevich, F. A., De Dominicis, F., De Jesus, M., de Marcillac, P., Dell'Oro, S., Di Domizio, S., Di Lorenzo, S., Dixon, T., Drobizhev, A., Dumoulin, L., Idrissi, M. El, Faverzani, M., Ferri, E., Ferri, F., Ferroni, F., Figueroa-Feliciano, E., Formaggio, J., Franceschi, A., Fu, S., Fujikawa, B. K., Gascon, J., Ghislandi, S., Giachero, A., Girola, M., Gironi, L., Giuliani, A., Gorla, P., Gotti, C., Grant, C., Gras, P., Guillaumon, P. V., Gutierrez, T. D., Han, K., Hansen, E. V., Heeger, K. M., Helis, D. L., Huang, H. Z., Hurst, M. T., Imbert, L., Juillard, A., Karapetrov, G., Keppel, G., Khalife, H., Kobychev, V. V., Kolomensky, Yu. G., Kowalski, R., Lattaud, H., Lefevre, M., Lisovenko, M., Liu, R., Liu, Y., Loaiza, P., Ma, L., Mancarella, F., Manenti, N., Mariani, A., Marini, L., Marnieros, S., Martinez, M., Maruyama, R. H., Mas, Ph., Mayer, D., Mazzitelli, G., Mazzola, E., Mei, Y., Moore, M. N., Morganti, S., Napolitano, T., Nastasi, M., Nikkel, J., Nones, C., Norman, E. B., Novosad, V., Nutini, I., O'Donnell, T., Olivieri, E., Olmi, M., Oregui, B. T., Pagan, S., Pageot, M., Pagnanini, L., Pasciuto, D., Pattavina, L., Pavan, M., Penek, Ö., Peng, H., Pessina, G., Pettinacci, V., Pira, C., Pirro, S., Pochon, O., Poda, D. V., Polakovic, T., Polischuk, O. G., Pottebaum, E. G., Pozzi, S., Previtali, E., Puiu, A., Puranam, S., Quitadamo, S., Rappoldi, A., Raselli, G. L., Ressa, A., Rizzoli, R., Rosenfeld, C., Rosier, P., Rossella, M., Scarpaci, J. A., Schmidt, B., Serino, R., Shaikina, A., Shang, K., Sharma, V., Shlegel, V. N., Singh, V., Sisti, M., Slocum, P., Speller, D., Surukuchi, P. T., Taffarello, L., Tomassini, S., Tomei, C., Torres, A., Torres, J. A., Tozzi, D., Tretyak, V. I., Trotta, D., Velazquez, M., Vetter, K. J., Wagaarachchi, S. L., Wang, G., Wang, L., Wang, R., Welliver, B., Wilson, J., Wilson, K., Winslow, L. A., Xie, F., Xue, M., Yang, J., Yefremenko, V., Umatov, V. I., Zarytskyy, M. M., Zhu, T., Zolotarova, A., and Zucchelli, S.
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Physics - Instrumentation and Detectors ,High Energy Physics - Experiment ,Nuclear Experiment - Abstract
CUPID, the CUORE Upgrade with Particle Identification, is a next-generation experiment to search for neutrinoless double beta decay ($0\nu\beta\beta$) and other rare events using enriched Li$_2$$^{100}$MoO$_4$ scintillating bolometers. It will be hosted by the CUORE cryostat located at the Laboratori Nazionali del Gran Sasso in Italy. The main physics goal of CUPID is to search for $0\nu\beta\beta$\ of $^{100}$Mo with a discovery sensitivity covering the full neutrino mass regime in the inverted ordering scenario, as well as the portion of the normal ordering regime with lightest neutrino mass larger than 10 meV. With a conservative background index of 10$^{-4}$ cnts/(keV$\cdot$kg$\cdot$yr), 240 kg isotope mass, 5 keV FWHM energy resolution and 10 live-years of data taking, CUPID will have a 90\% C.L. half-life exclusion sensitivity of 1.8 $\cdot$ 10$^{27}$ yr, corresponding to an effective Majorana neutrino mass ($m_{\beta\beta}$) sensitivity of 9--15 meV, and a $3\sigma$ discovery sensitivity of 1 $\cdot$ 10$^{27}$ yr, corresponding to an $m_{\beta\beta}$ range of 12--21 meV., Comment: Prepared for submission to EPJC; 24 pages, 6 figures, and 2 tables
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- 2025
6. Conditional diffusion model with spatial attention and latent embedding for medical image segmentation
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Hejrati, Behzad, Banerjee, Soumyanil, Glide-Hurst, Carri, and Dong, Ming
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Electrical Engineering and Systems Science - Image and Video Processing ,Computer Science - Computer Vision and Pattern Recognition - Abstract
Diffusion models have been used extensively for high quality image and video generation tasks. In this paper, we propose a novel conditional diffusion model with spatial attention and latent embedding (cDAL) for medical image segmentation. In cDAL, a convolutional neural network (CNN) based discriminator is used at every time-step of the diffusion process to distinguish between the generated labels and the real ones. A spatial attention map is computed based on the features learned by the discriminator to help cDAL generate more accurate segmentation of discriminative regions in an input image. Additionally, we incorporated a random latent embedding into each layer of our model to significantly reduce the number of training and sampling time-steps, thereby making it much faster than other diffusion models for image segmentation. We applied cDAL on 3 publicly available medical image segmentation datasets (MoNuSeg, Chest X-ray and Hippocampus) and observed significant qualitative and quantitative improvements with higher Dice scores and mIoU over the state-of-the-art algorithms. The source code is publicly available at https://github.com/Hejrati/cDAL/., Comment: 13 pages, 5 figures, 3 tables, Accepted in MICCAI 2024
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- 2025
7. Unsupervised Tomato Split Anomaly Detection using Hyperspectral Imaging and Variational Autoencoders
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Abdulsalam, Mahmoud, Zahidi, Usman, Hurst, Bradley, Pearson, Simon, Cielniak, Grzegorz, and Brown, James
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Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Artificial Intelligence - Abstract
Tomato anomalies/damages pose a significant challenge in greenhouse farming. While this method of cultivation benefits from efficient resource utilization, anomalies can significantly degrade the quality of farm produce. A common anomaly associated with tomatoes is splitting, characterized by the development of cracks on the tomato skin, which degrades its quality. Detecting this type of anomaly is challenging due to dynamic variations in appearance and sizes, compounded by dataset scarcity. We address this problem in an unsupervised manner by utilizing a tailored variational autoencoder (VAE) with hyperspectral input. Preliminary analysis of the dataset enabled us to select the optimal range of wavelengths for detecting this anomaly. Our findings indicate that the 530nm - 550nm range is suitable for identifying tomato dry splits. The analysis on reconstruction loss allow us to not only detect the anomalies but also to some degree estimate the anomalous regions., Comment: CVPPA Workshop
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- 2025
8. The Role of the School Nurse in E-Cigarette Prevention and Cessation: A Scoping Review
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Alanna J. Russell, Kawkab Shishani, and Sheila Hurst
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E-cigarettes have rapidly gained popularity among youth in recent years. This scoping review identifies opportunities for school nurses to incorporate e-cigarette prevention strategies into their practice and identifies gaps for future research in school nursing evidence-based practice. Using the methodological framework developed by Arksey and O'Malley and advanced by Levac et al., a literature review was conducted using PubMed, Cumulative Index to Nursing and Allied Health (CINAHL), and Education Resources Information Center (ERIC) databases. A total of 15 articles were included in the final review. Articles for inclusion addressed interventions aimed at reducing e-cigarette use in K-12 schools. The results highlight two general types of school-based interventions: (1) universal e-cigarette prevention education and (2) targeted e-cigarette use-cessation programs. Each of these types of interventions presents a leadership opportunity for school nurses to engage within all domains of their scope of practice.
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- 2025
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9. Nutritional knowledge and practices of low-income women during pregnancy: a qualitative study in two Oaxacan cities.
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Marian, Marian, Pérez, Ramona, McClain, Amanda, Hurst, Samantha, Reed, Elizabeth, Barker, Kathryn, and Lundgren, Rebecka
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Mexico ,Nutrition ,Nutrition practices ,Nutritional education ,Nutritional knowledge ,Nutritional supplements ,Pregnancy ,Prenatal care ,Humans ,Female ,Pregnancy ,Mexico ,Adult ,Health Knowledge ,Attitudes ,Practice ,Qualitative Research ,Poverty ,Young Adult ,Food Insecurity ,Pregnant People ,Social Support ,Diet - Abstract
BACKGROUND: Adequate dietary intake is critical for healthy pregnancies. Recent changes in social services in Mexico, coupled with high levels of food insecurity, call into question whether expecting women of the lowest socioeconomic status are able to meet their dietary and nutritional needs in this changing context. The aim of this study was to explore the nutritional practices, education and received and employed among women during their pregnancy. METHODS: Guided by Ecological Systems Theory and an Intersectionality Framework, this qualitative study was carried out in Oaxaca City and Puerto Escondido, in Oaxaca, a Mexican state with high levels of food insecurity. Women who had at least one child in the past five years and had lived in Oaxaca for the past five years were eligible to participate. Twenty-five women participated in semi-structured in-depth interviews conducted between June and December of 2023. A grounded theory approach was used for coding. NVivo was used for coding and analyses. RESULTS: Five key themes emerged linked to individual-level characteristics and the multiple social identities related to the social support for nutritional knowledge and practices among low-income Oaxacan women during pregnancy: (1) Life experiences, sociodemographic, and health characteristics that influence nutritional practices and knowledge during pregnancy; (2) Female family members as a primary source of nutritional knowledge and food support; (3) Support from other members of womens social networks; (4) Medical guidance for nutrition during pregnancy; and (5) Quality and gaps in the broader health care system and social services. These themes highlight how womens own experiences and social identities and the different interpersonal and community-level environments, particularly those of mothers and grandmothers and health care providers, interact and shape womens nutritional knowledge and practices, such as foods and nutritional supplements consumed, during pregnancy. CONCLUSION: Nutritional knowledge and practices during pregnancy are impacted by multiple social identities women have and different factors at the individual, group, and structural level. Future multi-level approaches in research and programming that take into consideration the individual, family members, and other social influences are needed to address the gaps in nutrition that women in Oaxaca go through during the prenatal period.
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- 2025
10. GPT-4o System Card
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OpenAI, Hurst, Aaron, Lerer, Adam, Goucher, Adam P., Perelman, Adam, Ramesh, Aditya, Clark, Aidan, Ostrow, AJ, Welihinda, Akila, Hayes, Alan, Radford, Alec, Mądry, Aleksander, Baker-Whitcomb, Alex, Beutel, Alex, Borzunov, Alex, Carney, Alex, Chow, Alex, Kirillov, Alex, Nichol, Alex, Paino, Alex, Renzin, Alex, Passos, Alex Tachard, Kirillov, Alexander, Christakis, Alexi, Conneau, Alexis, Kamali, Ali, Jabri, Allan, Moyer, Allison, Tam, Allison, Crookes, Amadou, Tootoochian, Amin, Tootoonchian, Amin, Kumar, Ananya, Vallone, Andrea, Karpathy, Andrej, Braunstein, Andrew, Cann, Andrew, Codispoti, Andrew, Galu, Andrew, Kondrich, Andrew, Tulloch, Andrew, Mishchenko, Andrey, Baek, Angela, Jiang, Angela, Pelisse, Antoine, Woodford, Antonia, Gosalia, Anuj, Dhar, Arka, Pantuliano, Ashley, Nayak, Avi, Oliver, Avital, Zoph, Barret, Ghorbani, Behrooz, Leimberger, Ben, Rossen, Ben, Sokolowsky, Ben, Wang, Ben, Zweig, Benjamin, Hoover, Beth, Samic, Blake, McGrew, Bob, Spero, Bobby, Giertler, Bogo, Cheng, Bowen, Lightcap, Brad, Walkin, Brandon, Quinn, Brendan, Guarraci, Brian, Hsu, Brian, Kellogg, Bright, Eastman, Brydon, Lugaresi, Camillo, Wainwright, Carroll, Bassin, Cary, Hudson, Cary, Chu, Casey, Nelson, Chad, Li, Chak, Shern, Chan Jun, Conger, Channing, Barette, Charlotte, Voss, Chelsea, Ding, Chen, Lu, Cheng, Zhang, Chong, Beaumont, Chris, Hallacy, Chris, Koch, Chris, Gibson, Christian, Kim, Christina, Choi, Christine, McLeavey, Christine, Hesse, Christopher, Fischer, Claudia, Winter, Clemens, Czarnecki, Coley, Jarvis, Colin, Wei, Colin, Koumouzelis, Constantin, Sherburn, Dane, Kappler, Daniel, Levin, Daniel, Levy, Daniel, Carr, David, Farhi, David, Mely, David, Robinson, David, Sasaki, David, Jin, Denny, Valladares, Dev, Tsipras, Dimitris, Li, Doug, Nguyen, Duc Phong, Findlay, Duncan, Oiwoh, Edede, Wong, Edmund, Asdar, Ehsan, Proehl, Elizabeth, Yang, Elizabeth, Antonow, Eric, Kramer, Eric, Peterson, Eric, Sigler, Eric, Wallace, Eric, Brevdo, Eugene, Mays, Evan, Khorasani, Farzad, Such, Felipe Petroski, Raso, Filippo, Zhang, Francis, von Lohmann, Fred, Sulit, Freddie, Goh, Gabriel, Oden, Gene, Salmon, Geoff, Starace, Giulio, Brockman, Greg, Salman, Hadi, Bao, Haiming, Hu, Haitang, Wong, Hannah, Wang, Haoyu, Schmidt, Heather, Whitney, Heather, Jun, Heewoo, Kirchner, Hendrik, Pinto, Henrique Ponde de Oliveira, Ren, Hongyu, Chang, Huiwen, Chung, Hyung Won, Kivlichan, Ian, O'Connell, Ian, Osband, Ian, Silber, Ian, Sohl, Ian, Okuyucu, Ibrahim, Lan, Ikai, Kostrikov, Ilya, Sutskever, Ilya, Kanitscheider, Ingmar, Gulrajani, Ishaan, Coxon, Jacob, Menick, Jacob, Pachocki, Jakub, Aung, James, Betker, James, Crooks, James, Lennon, James, Kiros, Jamie, Leike, Jan, Park, Jane, Kwon, Jason, Phang, Jason, Teplitz, Jason, Wei, Jason, Wolfe, Jason, Chen, Jay, Harris, Jeff, Varavva, Jenia, Lee, Jessica Gan, Shieh, Jessica, Lin, Ji, Yu, Jiahui, Weng, Jiayi, Tang, Jie, Yu, Jieqi, Jang, Joanne, Candela, Joaquin Quinonero, Beutler, Joe, Landers, Joe, Parish, Joel, Heidecke, Johannes, Schulman, John, Lachman, Jonathan, McKay, Jonathan, Uesato, Jonathan, Ward, Jonathan, Kim, Jong Wook, Huizinga, Joost, Sitkin, Jordan, Kraaijeveld, Jos, Gross, Josh, Kaplan, Josh, Snyder, Josh, Achiam, Joshua, Jiao, Joy, Lee, Joyce, Zhuang, Juntang, Harriman, Justyn, Fricke, Kai, Hayashi, Kai, Singhal, Karan, Shi, Katy, Karthik, Kavin, Wood, Kayla, Rimbach, Kendra, Hsu, Kenny, Nguyen, Kenny, Gu-Lemberg, Keren, Button, Kevin, Liu, Kevin, Howe, Kiel, Muthukumar, Krithika, Luther, Kyle, Ahmad, Lama, Kai, Larry, Itow, Lauren, Workman, Lauren, Pathak, Leher, Chen, Leo, Jing, Li, Guy, Lia, Fedus, Liam, Zhou, Liang, Mamitsuka, Lien, Weng, Lilian, McCallum, Lindsay, Held, Lindsey, Ouyang, Long, Feuvrier, Louis, Zhang, Lu, Kondraciuk, Lukas, Kaiser, Lukasz, Hewitt, Luke, Metz, Luke, Doshi, Lyric, Aflak, Mada, Simens, Maddie, Boyd, Madelaine, Thompson, Madeleine, Dukhan, Marat, Chen, Mark, Gray, Mark, Hudnall, Mark, Zhang, Marvin, Aljubeh, Marwan, Litwin, Mateusz, Zeng, Matthew, Johnson, Max, Shetty, Maya, Gupta, Mayank, Shah, Meghan, Yatbaz, Mehmet, Yang, Meng Jia, Zhong, Mengchao, Glaese, Mia, Chen, Mianna, Janner, Michael, Lampe, Michael, Petrov, Michael, Wu, Michael, Wang, Michele, Fradin, Michelle, Pokrass, Michelle, Castro, Miguel, de Castro, Miguel Oom Temudo, Pavlov, Mikhail, Brundage, Miles, Wang, Miles, Khan, Minal, Murati, Mira, Bavarian, Mo, Lin, Molly, Yesildal, Murat, Soto, Nacho, Gimelshein, Natalia, Cone, Natalie, Staudacher, Natalie, Summers, Natalie, LaFontaine, Natan, Chowdhury, Neil, Ryder, Nick, Stathas, Nick, Turley, Nick, Tezak, Nik, Felix, Niko, Kudige, Nithanth, Keskar, Nitish, Deutsch, Noah, Bundick, Noel, Puckett, Nora, Nachum, Ofir, Okelola, Ola, Boiko, Oleg, Murk, Oleg, Jaffe, Oliver, Watkins, Olivia, Godement, Olivier, Campbell-Moore, Owen, Chao, Patrick, McMillan, Paul, Belov, Pavel, Su, Peng, Bak, Peter, Bakkum, Peter, Deng, Peter, Dolan, Peter, Hoeschele, Peter, Welinder, Peter, Tillet, Phil, Pronin, Philip, Tillet, Philippe, Dhariwal, Prafulla, Yuan, Qiming, Dias, Rachel, Lim, Rachel, Arora, Rahul, Troll, Rajan, Lin, Randall, Lopes, Rapha Gontijo, Puri, Raul, Miyara, Reah, Leike, Reimar, Gaubert, Renaud, Zamani, Reza, Wang, Ricky, Donnelly, Rob, Honsby, Rob, Smith, Rocky, Sahai, Rohan, Ramchandani, Rohit, Huet, Romain, Carmichael, Rory, Zellers, Rowan, Chen, Roy, Chen, Ruby, Nigmatullin, Ruslan, Cheu, Ryan, Jain, Saachi, Altman, Sam, Schoenholz, Sam, Toizer, Sam, Miserendino, Samuel, Agarwal, Sandhini, Culver, Sara, Ethersmith, Scott, Gray, Scott, Grove, Sean, Metzger, Sean, Hermani, Shamez, Jain, Shantanu, Zhao, Shengjia, Wu, Sherwin, Jomoto, Shino, Wu, Shirong, Shuaiqi, Xia, Phene, Sonia, Papay, Spencer, Narayanan, Srinivas, Coffey, Steve, Lee, Steve, Hall, Stewart, Balaji, Suchir, Broda, Tal, Stramer, Tal, Xu, Tao, Gogineni, Tarun, Christianson, Taya, Sanders, Ted, Patwardhan, Tejal, Cunninghman, Thomas, Degry, Thomas, Dimson, Thomas, Raoux, Thomas, Shadwell, Thomas, Zheng, Tianhao, Underwood, Todd, Markov, Todor, Sherbakov, Toki, Rubin, Tom, Stasi, Tom, Kaftan, Tomer, Heywood, Tristan, Peterson, Troy, Walters, Tyce, Eloundou, Tyna, Qi, Valerie, Moeller, Veit, Monaco, Vinnie, Kuo, Vishal, Fomenko, Vlad, Chang, Wayne, Zheng, Weiyi, Zhou, Wenda, Manassra, Wesam, Sheu, Will, Zaremba, Wojciech, Patil, Yash, Qian, Yilei, Kim, Yongjik, Cheng, Youlong, Zhang, Yu, He, Yuchen, Zhang, Yuchen, Jin, Yujia, Dai, Yunxing, and Malkov, Yury
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Computer Science - Computation and Language ,Computer Science - Artificial Intelligence ,Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Computers and Society ,Computer Science - Machine Learning ,Computer Science - Sound ,Electrical Engineering and Systems Science - Audio and Speech Processing - Abstract
GPT-4o is an autoregressive omni model that accepts as input any combination of text, audio, image, and video, and generates any combination of text, audio, and image outputs. It's trained end-to-end across text, vision, and audio, meaning all inputs and outputs are processed by the same neural network. GPT-4o can respond to audio inputs in as little as 232 milliseconds, with an average of 320 milliseconds, which is similar to human response time in conversation. It matches GPT-4 Turbo performance on text in English and code, with significant improvement on text in non-English languages, while also being much faster and 50\% cheaper in the API. GPT-4o is especially better at vision and audio understanding compared to existing models. In line with our commitment to building AI safely and consistent with our voluntary commitments to the White House, we are sharing the GPT-4o System Card, which includes our Preparedness Framework evaluations. In this System Card, we provide a detailed look at GPT-4o's capabilities, limitations, and safety evaluations across multiple categories, focusing on speech-to-speech while also evaluating text and image capabilities, and measures we've implemented to ensure the model is safe and aligned. We also include third-party assessments on dangerous capabilities, as well as discussion of potential societal impacts of GPT-4o's text and vision capabilities.
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- 2024
11. Relay Incentive Mechanisms Using Wireless Power Transfer in Non-Cooperative Networks
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Hurst, Winston and Mostofi, Yasamin
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Computer Science - Computer Science and Game Theory ,Electrical Engineering and Systems Science - Systems and Control - Abstract
This paper studies the use of a multi-attribute auction in a communication system to bring about efficient relaying in a non-cooperative setting. We consider a system where a source seeks to offload data to an access point (AP) while balancing both the timeliness and energy-efficiency of the transmission. A deep fade in the communication channel (due to, e.g., a line-of-sight blockage) makes direct communication costly, and the source may alternatively rely on non-cooperative UEs to act as relays. We propose a multi-attribute auction to select a UE and to determine the duration and power of the transmission, with payments to the UE taking the form of energy sent via wireless power transfer (WPT). The quality of the channel from a UE to the AP constitutes private information, and bids consist of a transmission time and transmission power. We show that under a second-preferred-offer auction, truthful bidding by all candidate UEs forms a Nash Equilibrium. However, this auction is not incentive compatible, and we present a modified auction in which truthful bidding is in fact a dominant strategy. Extensive numerical experimentation illustrates the efficacy of our approach, which we compare to a cooperative baseline. We demonstrate that with as few as two candidates, our improved mechanism leads to as much as a 76% reduction in energy consumption, and that with as few as three candidates, the transmission time decreases by as much as 55%. Further, we see that as the number of candidates increases, the performance of our mechanism approaches that of the cooperative baseline. Overall, our findings highlight the potential of multi-attribute auctions to enhance the efficiency of data transfer in non-cooperative settings.
- Published
- 2024
12. Crowd Size Estimation for Non-Uniform Spatial Distributions with mmWave Radar
- Author
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Pallaprolu, Anurag, Kattekola, Aaditya Prakash, Hurst, Winston, Madhow, Upamanyu, Sabharwal, Ashutosh, and Mostofi, Yasamin
- Subjects
Electrical Engineering and Systems Science - Signal Processing - Abstract
Sensing with RF signals such as mmWave radar has gained considerable interest in recent years. This is particularly relevant to 6G networks, which aim to integrate sensing and communication (ISAC) capabilities for enhanced functionality. The contextual information provided by such sensing, whether collected by standalone non-ISAC units or integrated within ISAC, can not only optimize cellular network assets but can also serve as a valuable tool for a wide range of applications beyond network optimization. In this context, we present a novel methodology for crowd size estimation using monostatic mmWave radar, which is capable of accurately counting large crowds that are unevenly distributed across space. Our estimation approach relies on the rigorous derivation of occlusion probabilities, which are then used to mathematically characterize the probability distributions that describe the number of agents visible to the radar as a function of the crowd size. We then estimate the true crowd size by comparing these derived mathematical models to the empirical distribution of the number of visible agents detected by the radar. This method requires minimal sensing capabilities (e.g., angle-of-arrival information is not needed), thus being well suited for either a dedicated mmWave radar or an ISAC system. Extensive numerical simulations validate our methodology, demonstrating strong performance across diverse spatial distributions and for crowd sizes of up to (and including) 30 agents. We achieve a mean absolute error (MAE) of 0.48 agents, significantly outperforming a baseline which assumes that the agents are uniformly distributed in the area. Overall, our approach holds significant promise for a variety of applications including network resource allocation, crowd management, and urban planning.
- Published
- 2024
13. Multi-Attribute Auctions for Efficient Operation of Non-Cooperative Relaying Systems
- Author
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Hurst, Winston and Mostofi, Yasamin
- Subjects
Computer Science - Computer Science and Game Theory ,Electrical Engineering and Systems Science - Systems and Control - Abstract
This paper studies the use of a multi-attribute auction in a communication system to bring about efficient relaying in a non-cooperative setting. We consider a system where a source seeks to offload data to an access point (AP) while balancing both the timeliness and energy-efficiency of the transmission. A deep fade in the communication channel (due to, e.g., a line-of-sight blockage) makes direct communication costly, and the source may alternatively rely on non-cooperative UEs to act as relays. We propose a multi-attribute auction to select a UE and to determine the duration and power of the transmission, with payments to the UE taking the form of energy sent via wireless power transfer (WPT). The quality of the channel from a UE to the AP constitutes private information, and bids consist of a transmission time and transmission power. We show that under a second-preferred-offer auction, truthful bidding by all candidate UEs forms a Nash Equilibrium. However, this auction is not incentive compatible, and we present a modified auction in which truthful bidding is in fact a dominant strategy. Extensive numerical experimentation illustrates the efficacy of our approach, which we compare to a cooperative baseline. We demonstrate that with as few as two candidates, our improved mechanism leads to as much as a 76% reduction in energy consumption, and that with as few as three candidates, the transmission time decreases by as much as 55\%. Further, we see that as the number of candidates increases, the performance of our mechanism approaches that of the cooperative baseline. Overall, our findings highlight the potential of multi-attribute auctions to enhance the efficiency of data transfer in non-cooperative settings.
- Published
- 2024
14. Coacervation drives morphological diversity of mRNA encapsulating nanoparticles
- Author
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Pert, Emmit K., Hurst, Paul J., Waymouth, Robert M., and Rotskoff, Grant M.
- Subjects
Condensed Matter - Soft Condensed Matter - Abstract
The spatial arrangement of components within an mRNA encapsulating nanoparticle has consequences for its thermal stability, which is a key parameter for therapeutic utility. The mesostructure of mRNA nanoparticles formed with cationic polymers have several distinct putative structures: here, we develop a field theoretic simulation model to compute the phase diagram for amphiphilic block copolymers that balance coacervation and hydrophobicity as driving forces for assembly. We predict several distinct morphologies for the mesostructure of these nanoparticles, depending on salt conditions and hydrophobicity. We compare our predictions with cryogenic-electron microscopy images of mRNA encapsulated by charge altering releasable transporters. In addition, we provide a GPU-accelerated, open-source codebase for general purpose field theoretic simulations, which we anticipate will be a useful tool for the community.
- Published
- 2024
15. Optimizing the Optical Properties of Tin Oxide Aerogels through Defect Passivation
- Author
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Hardy II, John F., King, Madison, Hurst, Stephanie, and daCunha, Carlo R.
- Subjects
Condensed Matter - Materials Science - Abstract
Tin oxide aerogels were synthesized using an epoxide-assisted technique and characterized with Fourier transform infrared, X-ray diffraction, and UV-Vis to study the effects of post-synthesis annealing and peroxide treatment. While bulk tin oxide exhibits an optical bandgap of $3.6$ eV, its aerogel form often displays a larger apparent bandgap around $4.6$ eV due to defects. Our study reveals that annealing induces a partial phase change from SnO$_2$ to SnO, but is ineffective in removing defects. Conversely, peroxide passivation effectively lowers the bandgap and disorder levels, suggesting that dangling bonds are the primary cause of the increased bandgap in tin oxide aerogels. These findings offer insights for optimizing the optical properties of tin oxide aerogels for applications like solar cells.
- Published
- 2024
16. Beyond the Pale: Poor Whites as Uncontrolled Social Contagion in Harriet Beecher Stowe’s Dred
- Author
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Hurst, Allison L.
- Published
- 2020
- Full Text
- View/download PDF
17. Integrating Indigenous Science, Culture, and Social Justice Concerns into First-Year STEM Curriculum: Improving Intellectual Growth, Psychosocial Factors Associated with Retention, and Academic Achievement of Students from Racially Minoritized Groups Historically Underrepresented in STEM
- Author
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Amy Sprowles, Jessica Smith, Patricia Siering, Steven Margell, Frank Shaughnessy, Alison O'Dowd, Kerri J. Malloy, Matthew P. Hurst, P. Dawn Goley, Lisa Morehead-Hillman, Borbolla Mazzag, Gillian Black, L. Chook Chook Hillman, Dale Oliver, Katlin R. Goldenberg, Angela Rich, Sonja Manor, Matthew D. Johnson, and Eileen Cashman
- Abstract
Deficits in college degree attainment limit important perspectives and ways of knowing that inspire creativity and innovation. Disproportional outcomes for racially minoritized groups that are historically underrepresented in science, technology, engineering, and mathematics exacerbate this problem and promote societal inequities, structural racism, professional segregation, and racial wealth gaps. Culturally responsive programming that incorporates empathy and equity for non-majority populations can empower students from diverse backgrounds to achieve their educational goals. This paper describes the outcomes of a first-year place-based learning community in which students studied the science, culture, values, and social justice concerns of the Indigenous people of the Klamath River Basin by completing a water quality experiment alongside faculty, Indigenous scientists, and cultural experts. A combination of survey data and thematic analysis was used to evaluate the impact of the program on intellectual growth, gains in psychosocial factors associated with first-year student success, and academic achievement. All student participants demonstrated intellectual growth and gains in psychosocial factors associated with STEM retention, but the effects were most pronounced for students who identified parallels between issues faced by Native American communities and their home communities. The most significant gains in STEM retention and academic achievement occurred for URG students (students from underrepresented groups) who learned about Native American culture through the water quality laboratory. The majority of students expressed the importance of understanding the cultural, environmental, and/or social justice issues of Native American people to their future careers. We believe ours is one of the first studies that specifically examines the improved outcomes for first-year URG college STEM students that can result from curriculum that highlights scientific, cultural, and social justice concerns of Indigenous communities.
- Published
- 2024
18. Toward Spatial Control of Reaction Selectivity on Photocatalysts Using Area-Selective Atomic Layer Deposition on the Model Dual Site Electrocatalyst Platform.
- Author
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McNeary, W, Stinson, William, Waqar, Moaz, Zang, Wenjie, Pan, Xiaoqing, Esposito, Daniel, and Hurst, Katherine
- Subjects
area-selective deposition ,atomic layer deposition ,dual-site photocatalyst ,electrocatalysis ,hydrogen production ,oxide coatings ,scanning electrochemical microscopy - Abstract
Photocatalytic water splitting is a promising route to low-cost, green H2. However, this approach is currently limited in its solar-to-hydrogen conversion efficiency. One major source of efficiency loss is attributed to the high rates of undesired side and back reactions, which are exacerbated by the proximity of neighboring oxidation and reduction sites. Nanoscopic oxide coatings have previously been used to selectively block undesired reactants from reaching active sites; however, a coating encapsulating the entire photocatalyst particle limits activity as it cannot facilitate both half-reactions. In this work, area selective atomic layer deposition (AS-ALD) was used to selectively deposit semipermeable TiO2 films onto model metallic cocatalysts for enhancing reaction selectivity while maintaining a high overall activity. Pt and Au were used as exemplary reduction and oxidation cocatalyst sites, respectively, where Au was deactivated toward ALD growth through self-assembled thiol monolayers while TiO2 was coated onto Pt sites. Electroanalytical measurements of monometallic thin film electrodes showed that the TiO2-encapsulated Pt effectively suppressed undesired H2 oxidation and Fe(II)/Fe(III) redox reactions while still permitting the desired hydrogen evolution reaction (HER). A planar model photocatalyst platform containing patterned interdigitated arrays of Au and Pt microelectrodes was further assessed using scanning electrochemical microscopy (SECM), demonstrating the successful use of AS-ALD to enable local reaction selectivity in a dual-reaction-site (photo)electrocatalytic system. Finally, interdigitated microelectrodes having independent potential control were used to show that selectively deposited TiO2 coatings can suppress the rate of back reactions on neighboring active sites by an order of magnitude compared with uncoated control samples.
- Published
- 2024
19. Open ChCh
- Author
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Hurst, Abigail
- Published
- 2022
20. Honed to shine
- Author
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Hurst, Abigail
- Published
- 2022
21. Work ; Duplex with a difference, Sand-hills sentinel, Bringing the community and culture in
- Author
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Marriage, Guy, O'Sullivan, Michael, and Hurst, Abigail
- Published
- 2022
22. Supposing Truth is a Woman – What Then?
- Author
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Hurst, Andrea
- Subjects
JOURNALS: South African Journal of Philosophy: Postprints - Abstract
Nietzsche's analysis of the self-poisoning of ‘the will to power’ and his insistence upon overcoming its ideological outcome (the dogmatist's fake ‘Truth’) by recognizing the ‘un-truth’ of a ‘logic of contamination,’ demonstrates that he understands ‘truth’ as a paradox. What may one accordingly expect in response to the question ‘Supposing truth is a woman – what then?’, posed in the preface to Beyond Good and Evil (1966)? Supported by Derrida's Spurs: Nietzsche's Styles, I argue that Nietzsche could have drawn two radically different analogies between paradoxical ‘truth’ and ‘woman.’ However, due to the very kind of ideological conditioning (patriarchal), which his ‘free thinking’ resists in principle, he explicitly draws only one, hazarding a self-betraying performative contradiction. The obvious move might be to retain the valuable critique of ideology made possible by his analysis of the ‘will to power,’ while jettisoning the self-undermining rhetoric that constructs sexual difference according to values handed down by patriarchy. However, retaining and working through the terms of sexual difference, and highlighting Nietzsche's blindness concerning women, has the advantage of calling attention to its significance. The fact that one may say in retrospect that even Nietzsche (of all thinkers!) remained blindly subject to ideological conditioning, points to its unconscious nature and raises the question of what ‘overcoming’ in relation to the will to power entails for the free thinkers he heralded.
- Published
- 2007
23. Measurement resolution enhanced coherence for lattice fermions
- Author
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Hurst, H. M., Teoh, Yik Haw, and Spielman, I. B.
- Subjects
Condensed Matter - Quantum Gases ,Quantum Physics - Abstract
Weak measurement enables the extraction of targeted information from a quantum system while minimizing decoherence due to measurement backaction. However, in many-body quantum systems backaction can have unexpected effects on wavefunction collapse. We theoretically study a minimal many-particle model consisting of weakly measured non-interacting fermions in a one dimensional lattice. Repeated measurement of on-site occupation number with single-site resolution stochastically drives the system toward a Fock state, regardless of the initial state. This need not be the case for measurements that do not, even in principle, have single-site spatial resolution. We numerically show for systems with up to 16 sites that decreasing the spatial resolution strongly affects both the rate of stochastic evolution for each quantum trajectory and the allowed final states. The full Hilbert space can be partitioned into backaction-free subspaces (BFSs) the elements of which are indistinguishable to these measurements. Repeated measurements will drive any initial state into a single BFS, leading to a steady state that is a fixed point of the measurement process. We exactly calculate the properties of these BFSs for systems up to 32 sites and find that even for moderate reductions in measurement resolution they yield non-trivial steady state entanglement and coherence., Comment: Published version
- Published
- 2024
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- View/download PDF
24. Recurrence and survival after robotic vs laparoscopic liver resection in very-early to early-stage (BCLC 0-A) hepatocellular carcinoma
- Author
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Bernardi, Lorenzo, Balzano, Emanuele, Roesel, Raffaello, Senatore, Annamaria, Pezzati, Daniele, Catalano, Gabriele, Garo, Maria Luisa, Tincani, Giovanni, Majno-Hurst, Pietro, Ghinolfi, Davide, and Cristaudi, Alessandra
- Published
- 2025
- Full Text
- View/download PDF
25. Perceptions of sarcopenia in patients, health and care professionals, and the public: a scoping review of studies from different countries
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Lewis, Emma Grace, Hurst, Christopher, Errington, Linda, and Sayer, Avan A.
- Published
- 2025
- Full Text
- View/download PDF
26. Cross-sectional and longitudinal associations between glycaemic measures and grip strength in people without diabetes in the UK Biobank cohort study
- Author
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Granic, Antoneta, Cooper, Rachel, Hurst, Christopher, Hillman, Susan J., Dodds, Richard M., Witham, Miles D., and Sayer, Avan A.
- Published
- 2025
- Full Text
- View/download PDF
27. Pharmacology and Mechanism of Action of Suzetrigine, a Potent and Selective NaV1.8 Pain Signal Inhibitor for the Treatment of Moderate to Severe Pain
- Author
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Osteen, Jeremiah D., Immani, Swapna, Tapley, Tim L., Indersmitten, Tim, Hurst, Nicole W., Healey, Tiffany, Aertgeerts, Kathleen, Negulescu, Paul A., and Lechner, Sandra M.
- Published
- 2025
- Full Text
- View/download PDF
28. Intracerebroventricular B7-H3-targeting CAR T cells for diffuse intrinsic pontine glioma: a phase 1 trial
- Author
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Vitanza, Nicholas A., Ronsley, Rebecca, Choe, Michelle, Seidel, Kristy, Huang, Wenjun, Rawlings-Rhea, Stephanie D., Beam, Madison, Steinmetzer, Leonel, Wilson, Ashley L., Brown, Christopher, Beebe, Adam, Lindgren, Catherine, Gustafson, Joshua A., Wein, Amy, Holtzclaw, Susan, Hoeppner, Corrine, Goldstein, Hannah E., Browd, Samuel R., Hauptman, Jason S., Lee, Amy, Ojemann, Jeffrey G., Crotty, Erin E., Leary, Sarah E. S., Perez, Francisco A., Wright, Jason N., Alonso, Marta M., Dun, Matthew D., Foster, Jessica B., Hurst, Diana, Kong, Ada, Thomsen, Alison, Orentas, Rimas J., Albert, Catherine M., Pinto, Navin, Annesley, Colleen, Gardner, Rebecca A., Ho, On, Pattabhi, Sowmya, Gust, Juliane, Wendler, Jason P., Park, Julie R., and Jensen, Michael C.
- Published
- 2025
- Full Text
- View/download PDF
29. Lower Pregnancy and Live Birth Rates with Vaginal Endometrin Plus Intramuscular Progesterone Every Third Day Versus Intramuscular Progesterone Alone in Programmed Frozen Embryo Transfers: A Retrospective Case-control Study
- Author
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Ying, Luke Y., Hurst, Bradley S., Matthews, Michelle, Usadi, Rebecca, Coddington, Charles C., Eskew, Ashley M., and Ying, Ying
- Published
- 2025
- Full Text
- View/download PDF
30. Exploring Technical and Creative Posts in Online Live Coding Communities: An Analysis of Tidal Club and in_thread.
- Author
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William Payne 0003, Matthew Kaney, Izabella Rodrigues, and Amy Hurst
- Published
- 2025
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- View/download PDF
31. BEAST DB: Grand-Canonical Database of Electrocatalyst Properties
- Author
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Tezak, Cooper, Clary, Jacob, Gerits, Sophie, Quinton, Joshua, Rich, Benjamin, Singstock, Nicholas, Alherz, Abdulaziz, Aubry, Taylor, Clark, Struan, Hurst, Rachel, Del Ben, Mauro, Sutton, Christopher, Sundararaman, Ravishankar, Musgrave, Charles, and Vigil-Fowler, Derek
- Subjects
Condensed Matter - Materials Science ,Physics - Chemical Physics - Abstract
We present BEAST DB, an open-source database comprised of ab initio electrochemical data computed using grand-canonical density functional theory in implicit solvent at consistent calculation parameters. The database contains over 20,000 surface calculations and covers a broad set of heterogeneous catalyst materials and electrochemical reactions. Calculations were performed at self-consistent fixed potential as well as constant charge to facilitate comparisons to the computational hydrogen electrode. This article presents common use cases of the database to rationalize trends in catalyst activity, screen catalyst material spaces, understand elementary mechanistic steps, analyze electronic structure, and train machine learning models to predict higher fidelity properties. Users can interact graphically with the database by querying for individual calculations to gain granular understanding of reaction steps or by querying for an entire reaction pathway on a given material using an interactive reaction pathway tool. BEAST DB will be periodically updated, with planned future updates to include advanced electronic structure data, surface speciation studies, and greater reaction coverage., Comment: 24 pages, 8 figures
- Published
- 2024
32. Two-Shot Optimization of Compositionally Complex Refractory Alloys
- Author
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Paramore, James D., Butler, Brady G., Hurst, Michael T., Hastings, Trevor, Lewis, Daniel O., Norris, Eli, Barkai, Benjamin, Cline, Joshua, Miller, Braden, Cortes, Jose, Karaman, Ibrahim, Pharr, George M., and Arroyave, Raymundo
- Subjects
Condensed Matter - Materials Science - Abstract
In this paper, a synergistic computational/experimental approach is presented for the rapid discovery and characterization of novel alloys within the compositionally complex (i.e., "medium/high entropy") refractory alloy space of Ti-V-Nb-Mo-Hf-Ta-W. This was demonstrated via a material design cycle aimed at simultaneously maximizing the objective properties of high specific hardness (hardness normalized by density) and high specific elastic modulus (elastic modulus normalized by density). This framework utilizes high-throughput computational thermodynamics and intelligent filtering to first reduce the untenably large alloy space to a feasible size, followed by an iterative design cycle comprised of high-throughput synthesis, processing, and characterization in batch sizes of 24 alloys. After the first iteration, Bayesian optimization was utilized to inform selection of the next batch of 24 alloys. This paper demonstrates the benefit of using batch Bayesian optimization (BBO) in material design, as significant gains in the objective properties were observed after only two iterations or "shots" of the design cycle without using any prior knowledge or physical models of how the objective properties relate to the design inputs (i.e., composition). Specifically, the hypervolume of the Pareto front increased by 54% between the first and second iterations. Furthermore, 10 of the 24 alloys in the second iteration dominated all alloys from the first iteration.
- Published
- 2024
33. Uncrewed Vehicles in 6G Networks: A Unifying Treatment of Problems, Formulations, and Tools
- Author
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Hurst, Winston, Evmorfos, Spilios, Petropulu, Athina, and Mostofi, Yasamin
- Subjects
Electrical Engineering and Systems Science - Systems and Control ,Computer Science - Networking and Internet Architecture - Abstract
Uncrewed Vehicles (UVs) functioning as autonomous agents are anticipated to play a crucial role in the 6th Generation of wireless networks. Their seamless integration, cost-effectiveness, and the additional controllability through motion planning make them an attractive deployment option for a wide range of applications, both as assets in the network (e.g., mobile base stations) and as consumers of network services (e.g., autonomous delivery systems). However, despite their potential, the convergence of UVs and wireless systems brings forth numerous challenges that require attention from both academia and industry. This paper then aims to offer a comprehensive overview encompassing the transformative possibilities as well as the significant challenges associated with UV-assisted next-generation wireless communications. Considering the diverse landscape of possible application scenarios, problem formulations, and mathematical tools related to UV-assisted wireless systems, the underlying core theme of this paper is the unification of the problem space, providing a structured framework to understand the use cases, problem formulations, and necessary mathematical tools. Overall, the paper sets forth a clear understanding of how uncrewed vehicles can be integrated in the 6G ecosystem, paving the way towards harnessing the full potential at this intersection.
- Published
- 2024
34. Emergent Cooperation for Energy-efficient Connectivity via Wireless Power Transfer
- Author
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Hurst, Winston, Pallaprolu, Anurag, and Mostofi, Yasamin
- Subjects
Electrical Engineering and Systems Science - Systems and Control - Abstract
This paper addresses the challenge of incentivizing energy-constrained, non-cooperative user equipment (UE) to serve as cooperative relays. We consider a source UE with a non-line-of-sight channel to an access point (AP), where direct communication may be infeasible or may necessitate a substantial transmit power. Other UEs in the vicinity are viewed as relay candidates, and our aim is to enable energy-efficient connectivity for the source, while accounting for the self-interested behavior and private channel state information of these candidates, by allowing the source to ``pay" the candidates via wireless power transfer (WPT). We propose a cooperation-inducing protocol, inspired by Myerson auction theory, which ensures that candidates truthfully report power requirements while minimizing the expected power used by the source. Through rigorous analysis, we establish the regularity of valuations for lognormal fading channels, which allows for the efficient determination of the optimal source transmit power. Extensive simulation experiments, employing real-world communication and WPT parameters, validate our theoretical framework. Our results demonstrate over 71% reduction in outage probability with as few as 4 relay candidates, compared to the non-cooperative scenario, and as much as 70% source power savings compared to a baseline approach, highlighting the efficacy of our proposed methodology.
- Published
- 2024
35. Probing the active sites of oxide encapsulated electrocatalysts with controllable oxygen evolution selectivity
- Author
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Stinson, William DH, Stinson, Robert S, Jin, Jingjing, Chen, Zejie, Xu, Mingjie, Aydin, Fikret, Wang, Yinxian, Calegari Andrade, Marcos F, Pan, Xiaoqing, Pham, Tuan Anh, Hurst, Katherine E, Ogitsu, Tadashi, Ardo, Shane, and Esposito, Daniel V
- Subjects
Engineering ,Materials Engineering ,Chemical Sciences ,Nanotechnology ,Bioengineering - Abstract
Electrocatalysts encapsulated by nanoscopic overlayers can control the rate of redox reactions at the outer surface of the overlayer or at the buried interface between the overlayer and the active catalyst, leading to complex behavior in the presence of two competing electrochemical reactions. This study investigated oxide encapsulated electrocatalysts (OECs) comprised of iridium (Ir) thin films coated with an ultrathin (2-10 nm thick) silicon oxide (SiOx) or titanium oxide (TiOx) overlayer. The performance of SiOx|Ir and TiOx|Ir thin film electrodes towards the oxygen evolution reaction (OER) and Fe(ii)/Fe(iii) redox reactions were evaluated. An improvement in selectivity towards the OER was observed for all OECs. Overlayer properties, namely ionic and electronic conductivity, were assessed using a combination of electroanalytical methods and molecular dynamics simulations. SiOx and TiOx overlayers were found to be permeable to H2O and O2 such that the OER can occur at the MOx|Ir (M = Ti, Si) buried interface, which was further supported with molecular dynamics simulations of model SiO2 coatings. In contrast, Fe(ii)/Fe(iii) redox reactions occur to the same degree with TiOx overlayers having thicknesses less than 4 nm as bare electrocatalyst, while SiOx overlayers inhibit redox reactions at all thicknesses. This observation is attributed to differences in electronic transport between the buried interface and outer overlayer surface, as measured with through-plane conductivity measurements of wetted overlayer materials. These findings reveal the influence of oxide overlayer properties on the activity and selectivity of OECs and suggest opportunities to tune these properties for a wide range of electrochemical reactions.
- Published
- 2024
36. Psychosocial experiences are associated with human brain mitochondrial biology
- Author
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Trumpff, Caroline, Monzel, Anna S, Sandi, Carmen, Menon, Vilas, Klein, Hans-Ulrich, Fujita, Masashi, Lee, Annie, Petyuk, Vladislav A, Hurst, Cheyenne, Duong, Duc M, Seyfried, Nicholas T, Wingo, Aliza P, Wingo, Thomas S, Wang, Yanling, Thambisetty, Madhav, Ferrucci, Luigi, Bennett, David A, De Jager, Philip L, and Picard, Martin
- Subjects
Biological Psychology ,Biochemistry and Cell Biology ,Psychology ,Biological Sciences ,Behavioral and Social Science ,Social Determinants of Health ,Brain Disorders ,Human Genome ,Basic Behavioral and Social Science ,Aging ,Neurodegenerative ,Mental Illness ,Genetics ,Mental Health ,Neurosciences ,1.1 Normal biological development and functioning ,2.1 Biological and endogenous factors ,2.3 Psychological ,social and economic factors ,Generic health relevance ,Neurological ,Humans ,Mitochondria ,Male ,Oxidative Phosphorylation ,Female ,Brain ,Aged ,Stress ,Psychological ,Middle Aged ,Prefrontal Cortex ,Neurons ,Proteomics ,Affect ,single ,nucleus RNA sequencing (RNA ,seq) revealed strong cell ,type ,specific associations ,mitochondria | psychosocial factors | proteome | transcriptome | single cell RNA ,seq ,resolution ,positive psychosocial ,human brain health. ,mitochondria ,proteome ,psychosocial factors ,single cell RNA-seq ,transcriptome - Abstract
Psychosocial experiences affect brain health and aging trajectories, but the molecular pathways underlying these associations remain unclear. Normal brain function relies on energy transformation by mitochondria oxidative phosphorylation (OxPhos). Two main lines of evidence position mitochondria both as targets and drivers of psychosocial experiences. On the one hand, chronic stress exposure and mood states may alter multiple aspects of mitochondrial biology; on the other hand, functional variations in mitochondrial OxPhos capacity may alter social behavior, stress reactivity, and mood. But are psychosocial exposures and subjective experiences linked to mitochondrial biology in the human brain? By combining longitudinal antemortem assessments of psychosocial factors with postmortem brain (dorsolateral prefrontal cortex) proteomics in older adults, we find that higher well-being is linked to greater abundance of the mitochondrial OxPhos machinery, whereas higher negative mood is linked to lower OxPhos protein content. Combined, positive and negative psychosocial factors explained 18 to 25% of the variance in the abundance of OxPhos complex I, the primary biochemical entry point that energizes brain mitochondria. Moreover, interrogating mitochondrial psychobiological associations in specific neuronal and nonneuronal brain cells with single-nucleus RNA sequencing (RNA-seq) revealed strong cell-type-specific associations for positive psychosocial experiences and mitochondria in glia but opposite associations in neurons. As a result, these "mind-mitochondria" associations were masked in bulk RNA-seq, highlighting the likely underestimation of true psychobiological effect sizes in bulk brain tissues. Thus, self-reported psychosocial experiences are linked to human brain mitochondrial phenotypes.
- Published
- 2024
37. Toward an Authentic Understanding of Catholic School Identity
- Author
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Christopher Hurst
- Abstract
Researchers have studied Catholic schools for decades, often in an attempt to extrapolate from them lessons that may help public schools accomplish similar levels of academic achievement and other desirable goals, such as social mobility, social efficiency, and democratic equality. But research that attempts to understand Catholic education from a secular perspective inevitably misunderstands the purpose of education that Catholic schools themselves claim to pursue, i.e., beatitude. This unique purpose is the source of Catholic school identity. Here, Christopher Hurst argues that by considering Catholic education as the practice of a distinctly Catholic tradition, researchers can authentically assess how well Catholic schools are achieving their own stated goals, and whether their practices can be applied outside of a particular Catholic context.
- Published
- 2024
- Full Text
- View/download PDF
38. Implementation and Evaluation of a Multi-Level, Place-Based Tobacco Prevention and Control Program at a Minority-Serving Institution in Texas
- Author
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Brad Love, Rosemary Coffman, Charulata Ghosh, Jennifer Cofer, Alex N. Hurst, Katherine Oestman, Mayra Aquino, Lauren Kriss, Mansi Shah, Gerold Dermid, Margaret Raber, Ernest Hawk, Michael T. Walsh, and Ruth Rechis
- Abstract
Multi-level, place-based interventions have proven effective at promoting a range of health behaviors, including tobacco control and discouraging the uptake of tobacco products. This paper describes the implementation and impact of a 3-year, multi-level tobacco prevention and control program at a community-college minority-serving institution (MSI) on the Texas Gulf Coast within the context of a broader multi-sector, cross-functional health coalition. The intervention studied included a tobacco-free policy, a large-scale communication campaign highlighting parts of the intervention and prevention and cessation resources. The intervention was bolstered by the support of a community-led Steering Committee and tobacco control experts. Results from the first 3 years of implementation show that tobacco-free policies were largely supported by community members, awareness of the policy increased over time, and tobacco prevention and cessation resources were successfully embedded into campus norms. This multi-component approach shows how a community college was able to effectively reach students and staff on their campus to increase awareness of both the campus tobacco-free policy and the availability of tobacco prevention and cessation resources. Additionally, it also offers lessons for future tobacco prevention and control work in higher education.
- Published
- 2024
- Full Text
- View/download PDF
39. Institutionalizing Internal Goods through Catholic School Identity
- Author
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Christopher Hurst
- Abstract
Catholic schools, in order to be Catholic, lay claim to a particular sense of what these schools are and what they are not; that is, they claim Catholic school identity. Organizations such as Catholic schools have a strong identity if these claims are central to their core mission, distinct from the claims of other organizations, and consistent over time. The distinctiveness of Catholic school identity implies that Catholic educational practice must be rooted in a particularly Catholic tradition, and the centrality of Catholic school identity implies that excellent Catholic schools can derive internal goods only available to these schools. But claims to a distinct identity are undercut by the pursuit of external goods such as wealth, power, and prestige, as these external goods are neither central to the mission of any school, nor do they distinguish Catholic schools from other forms of school. In particular, Catholic school principals must balance their schools' need for legitimacy with their desire to claim a strong Catholic identity. This paper provides a framework for understanding the internal goods that comprise Catholic school identity, the external goods these schools need to survive, and the process of judgment principals must use to maintain Catholic school identity.
- Published
- 2024
- Full Text
- View/download PDF
40. The role of cross- and interdisciplinary climate research centres
- Author
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Herziger, Atar and Hurst, Kristin F.
- Published
- 2025
- Full Text
- View/download PDF
41. Integrated Science Teaching in Atmospheric Ice Nucleation Research: Immersion Freezing Experiments
- Author
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Elise K. Wilbourn, Sarah Alrimaly, Holly Williams, Jacob Hurst, Gregory P. McGovern, Todd A. Anderson, and Naruki Hiranuma
- Abstract
This paper introduces hands-on curricular modules integrated with research in atmospheric ice nucleation, which is an important phenomenon potentially influencing global climate change. The primary goal of this work is to promote meaningful laboratory exercises to enhance the competence of students in the fields of science, technology, engineering, and math (STEM) by applying an appropriate methodology to laboratory ice nucleation measurements. To achieve this goal, three laboratory modules were developed with 18 STEM interns and tested by 28 students in a classroom setting. Students were trained to experimentally simulate atmospheric ice nucleation and cloud droplet freezing. For practical training, this work utilized a simple freezing assay device called the West Texas Cryogenic Refrigerator Applied to Freezing Test (WT-CRAFT) system. More specifically, students were provided with hands-on lessons to calibrate WT-CRAFT with deionized water and apply analytical techniques to understand the physicochemical properties of bulk water and droplet freezing. All procedures to implement the developed modules were typewritten during this process, and shareable read-ahead exploration materials were developed and compiled as a curricular product. Additionally, students conducted complementary analyses to identify possible catalysts of heterogeneous freezing in the water. The water analyses included: pH, conductivity, surface tension, and electron microscopy-energy-dispersive X-ray spectroscopy. During the data and image analysis process, students learned how to analyze droplet freezing spectra as a function of temperature, screen and interpret the data, perform uncertainty analyses, and estimate ice nucleation efficiency using computer programs. Based on the formal program assessment of learning outcomes and direct (yet deidentified) student feedback, we broadly achieved our goals to (1) improve their problem-solving skills by combining multidisciplinary science and math skills and (2) disseminate data and results with variability and uncertainty. The developed modules can be applied at any institute to advance undergraduate and graduate curricula in environmental science.
- Published
- 2023
- Full Text
- View/download PDF
42. An exploratory study on the benefits of transit orientated development (TOD) to rail infrastructure projects
- Author
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Farnes, Ken, Hurst, Neville, Wong, Woon-Weng, and Wilkinson, Sara
- Published
- 2025
- Full Text
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43. A novel method of refining the performance of rail systems: an evaluation of system dynamics using discrete event simulation
- Author
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Gharehbaghi, Koorosh, Farnes, Ken, and Hurst, Neville
- Published
- 2025
- Full Text
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44. Transcervical Fibroid Ablation (TFA): Current Status and New Developments
- Author
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Roy, K. H., Lindner, Leslie Hansen, Gill, Tasha L., and Hurst, Bradley S.
- Published
- 2024
- Full Text
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45. The role of dairy alternatives in just food system transitions: a scoping review
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Hurst, Georgie and Pant, Laxmi Prasad
- Published
- 2024
- Full Text
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46. Erklärbare künstliche Intelligenz im CRISP-DM-Prozess
- Author
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Hurst, Marco, Wentzien, Marcel, and Schmalzried, Dirk
- Published
- 2024
- Full Text
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47. Challenges in Paediatric Xenotransplantation: Ethical Components Requiring Distinct Attention in Children and Obligations to Patients and Society
- Author
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Merlocco, Anthony and Hurst, Daniel J.
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- 2024
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48. A kinematically complex multi-articular motor skill for investigating implicit motor learning
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Solomon, Jack P., Hurst, Austin J., Kraeutner, Sarah N., Ingram, Tony G. J., and Boe, Shaun G.
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- 2024
- Full Text
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49. Which Are the Optimal Screening Tools for Internet Use Disorder in Children and Adolescents? A Systematic Review of Psychometric Evidence
- Author
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Schlossarek, Samantha, Hohls, Lisa, Schmidt, Hannah, Bischof, Anja, Bischof, Gallus, Brandt, Dominique, Borgwardt, Stefan, Browne, Dillon T., Christakis, Dimitri, Pietra, Pamela Hurst-Della, Demetrovics, Zsolt, and Rumpf, Hans-Jürgen
- Published
- 2024
- Full Text
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50. Topological analysis and experimental control of transformations of domain walls in magnetic cylindrical nanowires
- Author
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Álvaro-Gómez, L., Hurst, J., Hegde, S., Ruiz-Gómez, S., Pereiro, E., Aballe, L., Toussaint, J. C, Pérez, L., Masseboeuf, A., Thirion, C., Fruchart, O., and Gusakova, D.
- Subjects
Condensed Matter - Mesoscale and Nanoscale Physics ,Mathematical Physics - Abstract
Topology is a powerful tool for categorizing magnetization textures, highlighting specific features in both 2D systems, such as thin films or curved surfaces, and in 3D bulk systems. In the emerging field of 3D nanomagnetism within confined geometries, the contributions from both volume and surface must be considered, requiring appropriate topological analysis to obtain a complete view of the system. Here, we consider domain walls in cylindrical magnetic nanowires to illustrate the use of topological invariants. We begin with micromagnetic simulations of domain wall transformation under the stimulus of an \OErsted field, tracking bulk and surface topological signatures, and analyzing the interplay between multiple micromagnetic objects. For instance, the extensive analysis allowed us to highlight mechanisms of domain wall type conversion from topologically non-trivial to trivial states, a phenomenon disregarded in previous studies. Additionally, we provide experimental evidence of the transient states predicted to occur during the dynamical process.
- Published
- 2024
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