485 results on '"Hurley, James B."'
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2. Acetyl-CoA carboxylase inhibition increases retinal pigment epithelial cell fatty acid flux and restricts apolipoprotein efflux
3. CRISPR editing of anti-anemia drug target rescues independent preclinical models of retinitis pigmentosa
4. Aerobic Glycolysis in Photoreceptors Supports Energy Demand in the Absence of Mitochondrial Coupling
5. A versatile pumpless multi-channel fluidics system for maintenance and real-time functional assessment of tissue and cells
6. Proline provides a nitrogen source in the retinal pigment epithelium to synthesize and export amino acids for the neural retina
7. Non-photopic and photopic visual cycles differentially regulate immediate, early, and late phases of cone photoreceptor-mediated vision
8. Reassessing retinal pigment epithelial ketogenesis: Enzymatic assays for ketone body levels provide inaccurate results
9. Mitochondria: The Retina’s Achilles’ Heel in AMD
10. Absence of retbindin blocks glycolytic flux, disrupts metabolic homeostasis, and leads to photoreceptor degeneration
11. Daily mitochondrial dynamics in cone photoreceptors
12. Loss of MPC1 reprograms retinal metabolism to impair visual function
13. Increasing Ca2+ in photoreceptor mitochondria alters metabolites, accelerates photoresponse recovery, and reveals adaptations to mitochondrial stress
14. How Excessive cGMP Impacts Metabolic Proteins in Retinas at the Onset of Degeneration
15. Mitochondria: The Retina’s Achilles’ Heel in AMD
16. Acetyl-CoA carboxylase inhibition increases RPE cell fatty acid oxidation and limits apolipoprotein efflux
17. Medium Depth Influences O2 Availability and Metabolism in Human RPE Cultures
18. Editorial: Retinal metabolism in health and disease.
19. Leber Congenital Amaurosis Linked to AIPL1: A Mouse Model Reveals Destabilization of cGMP Phosphodiesterase
20. A Zebrafish Model for Pyruvate Dehydrogenase Deficiency: Rescue of Neurological Dysfunction and Embryonic Lethality Using a Ketogenic Diet
21. Maintaining and Assessing Various Tissue and Cell Types of the Eye Using a Novel Pumpless Fluidics System
22. Decision letter: Photoreceptor disc incisures form as an adaptive mechanism ensuring the completion of disc enclosure
23. AIPL1, a Protein Implicated in Leber's Congenital Amaurosis, Interacts with and Aids in Processing of Farnesylated Proteins
24. Energy Metabolism in the Vertebrate Retina
25. Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium
26. Mitochondrial Calcium Uniporter (MCU) deficiency reveals an alternate path for Ca2+ uptake in photoreceptor mitochondria
27. Biochemical Analysis of a Dimerization Domain Mutation in RetGC-1 Associated with Dominant Cone-Rod Dystrophy
28. Abnormal Photoresponses and Light-Induced Apoptosis in Rods Lacking Rhodopsin Kinase
29. Two Amino Acid Substitutions Convert a Guanylyl Cyclase, RetGC-1, into an Adenylyl Cyclase
30. Proline provides a nitrogen source in the retinal pigment epithelium to synthesize and export amino acids for the neural retina
31. Medium depth influences O2availability and metabolism in cultured RPE cells
32. The Core Domain of a New Retina Specific RGS Protein Stimulates the GTPase Activity of Transducin in vitro
33. Responses of the Phototransduction Cascade to Dim Light
34. How Excessive cGMP Impacts Metabolic Proteins in Retinas at the Onset of Degeneration
35. The multi-tissue landscape of somatic mtDNA mutations indicates tissue-specific accumulation and removal in aging
36. Author response: The multi-tissue landscape of somatic mtDNA mutations indicates tissue-specific accumulation and removal in aging
37. CRISPR-Editing of Anti-Anemia Drug Target Rescues Independent Preclinical Models of Retinitis Pigmentosa
38. Transducin-Deficient Rod Photoreceptors Evaluated With Optical Coherence Tomography and Oxygen Consumption Rate Energy Biomarkers
39. Decision letter: The Na+/K+ pump dominates control of glycolysis in hippocampal dentate granule cells
40. Multi-tissue landscape of somatic mtDNA mutations indicates tissue specific accumulation and removal in aging
41. Pyruvate kinase and aspartate-glutamate carrier distributions reveal key metabolic links between neurons and glia in retina
42. Pyruvate kinase M2 regulates photoreceptor structure, function, and viability
43. Biochemical Function of the LCA Linked Protien, Aryl Hydrocarbon Receptor Interacting Protein Like-1 (AIPL1) : Role of AIPL1 in retina
44. Succinate metabolism in the retinal pigment epithelium uncouples respiration from ATP synthesis
45. Cytosolic reducing power preserves glutamate in retina
46. Na v 1.1 Channels are critical for intercellular communication in the suprachiasmatic nucleus and for normal circadian rhythms
47. Monocarboxylate Transporter 1 (MCT1) Mediates Succinate Export in the Retina
48. Flow of energy in the outer retina in darkness and in light
49. Correction: Fluidics system for resolving concentration-dependent effects of dissolved gases on tissue metabolism
50. Extracellular matrix dysfunction in Sorsby patient-derived retinal pigment epithelium
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