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12 results on '"Hulzink, J."'

1. Design of 100 muW wireless sensor nodes for biomedical monitoring

Author

Yseboodt, L., de Nil, M., Huisken, J., Berekovic, M., Zhao, Q., Bouwens, F., Hulzink, J., van Meerbergen, J., Yseboodt, L., de Nil, M., Huisken, J., Berekovic, M., Zhao, Q., Bouwens, F., Hulzink, J., and van Meerbergen, J.

Abstract

Wireless sensor nodes span a wide range of applications. This paper focuses on the biomedical area, more specifically on healthcare monitoring applications. Power dissipation is the dominant design constraint in this domain. This paper shows the different steps to develop a digital signal processing architecture for a single channel electrocardiogram application, which is used as an application example. The target power consumption is 100 μW as that is the power energy scavengers can deliver. We follow a bottleneck-driven approach: first the algorithm is tuned to the target processor, then coarse grained clock-gating is applied, next the static as well as the dynamic dissipation of the digital processor is reduced by tuning the core to the target domain. The impact of each step is quantified. A solution of 11 μW is possible for both radio and DSP running the electrocardiogram algorithm.

Published
2009

3. Ultra Low Power programmable biomedical SoC for on-body ECG and EEG processing

Author

Busze, B., primary, de Groot, H., additional, Santana, O., additional, Abbo, A., additional, Yseboodt, L., additional, van Meerbergen, J., additional, Bennebroek, M., additional, Bouwens, F., additional, Konijnenburg, M., additional, De Nil, M., additional, Ashouei, M., additional, Hulzink, J., additional, Zhou, J., additional, Stuyt, J., additional, and Huisken, J., additional

Published
2010
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11. An ultra low energy biomedical signal processing system operating at near-threshold.

Author

Hulzink J, Konijnenburg M, Ashouei M, Breeschoten A, Berset T, Huisken J, Stuyt J, de Groot H, Barat F, David J, and Van Ginderdeuren J

Abstract

This paper presents a voltage-scalable digital signal processing system designed for the use in a wireless sensor node (WSN) for ambulatory monitoring of biomedical signals. To fulfill the requirements of ambulatory monitoring, power consumption, which directly translates to the WSN battery lifetime and size, must be kept as low as possible. The proposed processing platform is an event-driven system with resources to run applications with different degrees of complexity in an energy-aware way. The architecture uses effective system partitioning to enable duty cycling, single instruction multiple data (SIMD) instructions, power gating, voltage scaling, multiple clock domains, multiple voltage domains, and extensive clock gating. It provides an alternative processing platform where the power and performance can be scaled to adapt to the application need. A case study on a continuous wavelet transform (CWT)-based heart-beat detection shows that the platform not only preserves the sensitivity and positive predictivity of the algorithm but also achieves the lowest energy/sample for ElectroCardioGram (ECG) heart-beat detection publicly reported today.

Published
2011
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12. The expression of tgas118, encoding a defensin in Lycopersicon esculentum, is regulated by gibberellin.

Author

van den Heuvel KJ, Hulzink JM, Barendse GW, and Wullems GJ

Subjects
Amino Acid Sequence, Cloning, Molecular, DNA, Complementary, DNA, Plant isolation & purification, Gibberellins metabolism, Molecular Sequence Data, Mutation, Plant Growth Regulators metabolism, Plant Structures cytology, Plant Structures drug effects, Plant Structures genetics, RNA, Messenger isolation & purification, RNA, Plant, Defensins genetics, Defensins metabolism, Gene Expression Regulation, Plant, Gibberellins pharmacology, Solanum lycopersicum genetics, Plant Growth Regulators pharmacology, Plant Proteins genetics
Abstract

A flower specific cDNA, tgas118, has been isolated after differential screening of a gib-1 anther cDNA library of Lycopersicon esculentum. The corresponding mRNA was present in all tissues analysed. Northern blot analysis revealed that in wild-type tomato the gene was predominantly expressed throughout flower development, while in the gibberellin (GA)-deficient mutant of tomato (gib-1) the abundance declined. Treatment of the mutant with GA resulted in an accumulation of the tgas118 mRNA within hours in leaf and bud tissues. In the leaf, GA1, GA3 and GA9 were effective in enhancing the expression while GA4 was not. In addition to GA, wounding and dehydration also increased the accumulation of tgas118 mRNA in leaf tissue. In situ hybridization showed that application of 50 ng GA3 bud(-1) induced a similar spatial expression of the tgas118 mRNA in gib-1 buds 24 h post treatment to that found in wild-type flower buds. The deduced TGAS118 protein displays up to 77% similarity with defensins and as its expression is up-regulated by stimuli such as wounding it is proposed that it may play a role in protection against pathogens.

Published
2001
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