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27 results on '"Hulya Sungurtekin"'

2. Comparison of Spinal, Low-Dose Spinal and Epidural Anesthesia With Ropivacaine Plus Fentanyl for Transurethral Surgical Procedures

Author

Baris Ulker, Riza Hakan Erbay, Simay Serin, and Hulya Sungurtekin

Subjects
epidural anesthesia, low-dose spinal anesthesia, ropivacaine, transurethral surgery, Medicine (General), R5-920
Abstract

The aim of This study was to compare spinal, low-dose spinal, and epidural anesthesia using ropivacaine and fentanyl combinations for transurethral surgical procedures. Sixty patients with American Society of Anesthesiologists scores of I–III were allocated into three groups. After pre- loading with 5 mL/kg normal saline, patients in the spinal anesthesia group (Group S) received 15 mg of hyperbaric ropivacaine plus 25 μg of fentanyl intrathecally; patients in the epidural anesthesia group (Group E) received 112.5 mg of ropivacaine plus 25 μg of fentanyl epidurally via an epidural catheter; and patients in the low-dose spinal anesthesia group (Group L) received 10 mg of hyperbaric ropivacaine plus 25 μg of fentanyl intrathecally. Blood pressure, heart rate, peripheral oxygen saturation, time to onset of thoracic (T)-10 dermatome, two-segment sensorial block regression time, full recovery of sensorial block, maximum motor blockade levels, motor blockade regression time, additional analgesic administration, patient comfort, and complications were recorded. The time to the onset of T10 dermatome level was shortest in Group S and longest in Group E (p < 0.001). The sensorial blockade time and motor blockade regression time were shorted in Group L (p < 0.001). The two-segment sensorial block regression time in Group E exceeded that in the other groups. Additional analgesic administration was not needed in any group. No complications or adverse effects were observed in any patient. We conclude that all three anesthetic techniques may be used safely and are appropriate for transurethral surgical procedures. However, low-dose spinal anesthesia with ropivacaine plus fentanyl may be preferable in transurethral surgery because we reach an adequate sensorial level with less motor blockade.

Published
2010
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4. Secondary Infection and Co-infection in COVID-19 Patients Receiving Tocilizumab

Author

Çağla Erdoğan, Metin Kılınç, Beyza Şahin, and Hülya Sungurtekin

Subjects
seconder infection, covid-19, tocilizumab, Medicine, Internal medicine, RC31-1245, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Objective: Tocilizumab (TCZ) is a recombinant humanized anti-IL-6 receptor monoclonal antibody that is beneficial in critically ill COVID-19 patients. However, the clinical efficacy and safety of immunosuppressants (including tocilizumab, sarilumab and anakinra) in COVID-19 patients are not yet known. These treatments may predispose patients to infection. The aim of this study was to find any connection between the use of tocilizumab and increased secondary bacterial infections. Materials and Methods: In this study, we conducted retrospective analyses of secondary bacterial infections in COVID-19 patients in the intensive care unit. This study included patients with laboratory-confirmed COVID-19 infection or clinically and radiologically confirmed COVID-19 infections who were admitted to the university hospital adult ICUs between March 2020 and January 2022. Demographic data, recent exposure and travel history, clinical symptoms or signs, laboratory findings, and comorbidities were recorded. Microbial cultures from tracheal aspirates, blood, and urine were obtained at admission and throughout the hospital stay. The patients who received tocilizumab treatment noted and analyzed for seconder infections. Blood cultures were taken at least 48 h after the first dose of tocilizumab. Results: We found that 80 patients (%37) had positive culture samples at admission, and most of these cases were admitted to the ICU from various hospital wards. The analyzed data showed that the tocilizumab group had a higher incidence of positive culture samples (%75 vs %35, p=0,0001). The results showed that culture of tocilizumab taken patients had more incidence with metisilin resistance S. aureus, Klebsiella spp., and Acinetobacter spp. (p=0,0001). Infection and mortality rates were much higher than those in the usual care group. Conclusion: Secondary infections and sepsis are major risk factors for mortality. The pathogens detected were drug resistant and had a lower chance of treatment. The benefit of tocilizumab treatment was lost in these patients because of secondary infections. Future studies are needed to help determine the risks of tocilizumab treatments.

Published
2024
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6. Malnutrition and associated risk factors in nursing home residents in Turkey

Author

Fatih Sumer, Sadik Kilicturgay, Kubilay Demirag, Gulistan Bahat Ozturk, Osman Abbasoglu, Zeynel Abidin Öztürk, Zekeriya Ulger, Ozlem Yilmaz, Derya Hopanci Bicakli, Hulya Sungurtekin, Meltem Halil, S. Muratli, and Cafer Balci

Subjects
Malnutrition, business.industry, Environmental health, medicine, General Medicine, medicine.disease, business, Nursing homes
Published
2020

7. Spontaneous Pneumothorax and Pneumomediastinum in Covid-19 Pneumonia

Author

Cagla Erdogan, Metin Kilinc, Selvinaz Tanriverdi Yuksel, and Hulya Sungurtekin

Subjects
pneumomediastinum, pneumothorax, COVID-19, subcutaneous emphysema, Critical Care and Intensive Care Medicine
Abstract

Fifteen to twelve percent of COVID-19 patients who had mild to severe semptoms were hospitalized. Most of hospitalized patients had respiratory failure and admitted to the intensive care unit with the diagnosis of acute respiratory distress syndrome (ARDS). Pneumothorax (PX) and pneumomediastinum (PM) which can be seen as travmatic or spontaneous in intensive care unit (ICU) patients have a higher incidence in COVID-19 patients. Patients that admitted to ICU between April 2020 and November 2021, were reviewed for development of pneumothorax, pneumomediastinum and subcutaneous emphysema retrospectively. There was 13 patients who were developed these conditions in the study period. Five of them was male and median age for all patients was 62. Eight of them were intubated and mechanically ventilated. Only two of them discharged from ICU. The most common reason for death was sepsis due to secondary infections. Patients followed with physical examination, chest XR and computerized tomography (CT) if needed. Acute deterioation, increased oxygen demand and crepitation in the physical examination should be alarming findings in COVID-19 patients for PX and PM. Early management of these symptoms can be life saving.

Published
2022

8. Evaluation of the End-stage Patients in Intensive Care

Author

Hülya Sungurtekin and Semiha Yalçın

Subjects
end-stage patient, palliative care, intensive care unit, cost, Medicine, Internal medicine, RC31-1245, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Objective: The benefit of medical interventions applied in terminal patients who have no hope of recovery and whose death is thought to be approaching is still a controversial issue. In this study, it was aimed to analyze the terminal stage patients hospitalized in the intensive care unit. Materials and Methods: The general characteristics and laboratory results of 61 end-stage patients admitted to the adult intensive care unit of university hospital between December 2016 and may 2017 were examined. Life expectancy, mortality rates, factors affecting mortality, and costs per patient were evaluated according to the palliative prognostic index (PPI) and palliative care admission score (PCAS) of the patients. Results: Exitus patients had an average of 13.83 days of intensive care stay and patients who survived had a mean 30.69 days (p

Published
2023
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9. Evaluation of Alveolo-arterial Oxygen Gradient and Mortality in Different Respiratory Support Methods in Severe COVID-19 Patients Followed in the Intensive Care Unit

Author

Fatih Sargın, Anıl Kuvandık, Simay Karaduman, and Hülya Sungurtekin

Subjects
covid-19, nasal cannula, oxygen treatment, alveolo-arterial oxygen gradient, mechanical ventilation, Medicine, Internal medicine, RC31-1245, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Objective:Severe pneumonia is an important cause of mortality in coronavirus disease-2019 (COVID-19) infection. This study evaluated pulmonary gas exchange and mortality according to nasal cannula, high flow nasal cannula, non-invasive positive pressure ventilation and invasive mechanical ventilation used for treating hypoxemic respiratory failure in severe COVID-19 patients.Materials and Methods:Hundred and forty severe COVID-19 patients who were treated in Department of Anesthesiology Intensive Care Unit of Pamukkale University Hospital were reviewed retrospectively. Arterial blood gas results on the 1st, 3rd, 7th, 14th, and 21st days of admission were recorded.Results:The alveolo-arterial oxygen gradient of the patients receiving oxygen via nasal cannula was significantly lower than the patients receiving high-flow nasal cannula, non-invasive and invasive mechanical ventilation. When the other groups were compared, no significant difference was observed between the alveolo-arterial oxygen gradients of the patients who received high-flow nasal cannula, non-invasive and invasive mechanical ventilation support. We observed that the mortality of the patients who were admitted as intubated was significantly higher than the other groups.Conclusion:Invasive and non-invasive oxygen support resulted in similar alveolo-arterial oxygen gradients in severe COVID-19 patients at admission and at 3-week follow-up, but mortality was higher in intubated patients.

Published
2023
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10. International Nosocomial Infection Control Consortium report, data summary of 50 countries for 2010-2015: Device-associated module

Author

Víctor Daniel Rosenthal, Hail M. Al-Abdely, Amani Ali El-Kholy, Safa A Aziz AlKhawaja, Hakan Leblebicioglu, Yatin Mehta, Vineya Rai, Nguyen Viet Hung, Souha Sami Kanj, Mona Foda Salama, Estuardo Salgado-Yepez, Naheed Elahi, Rayo Morfin Otero, Anucha Apisarnthanarak, Braulio Matias De Carvalho, Bat Erdene Ider, Dale Fisher, Maria Carmen S.G. Buenaflor, Michael M. Petrov, Ana Marcela Quesada-Mora, Farid Zand, Vaidotas Gurskis, Tanja Anguseva, Aamer Ikram, Daisy Aguilar de Moros, Wieslawa Duszynska, Nepomuceno Mejia, Florin George Horhat, Vladislav Belskiy, Vesna Mioljevic, Gabriela Di Silvestre, Katarina Furova, Gloria Y. Ramos-Ortiz, May Osman Gamar Elanbya, Hindra Irawan Satari, Umesh Gupta, Tarek Dendane, Lul Raka, Humberto Guanche-Garcell, Bijie Hu, Denis Padgett, Kushlani Jayatilleke, Najla Ben Jaballah, Eleni Apostolopoulou, Walter Enrique Prudencio Leon, Alejandra Sepulveda-Chavez, Hector Miguel Telechea, Andrew Trotter, Carlos Alvarez-Moreno, Luis Kushner-Davalos, J.E. Desse, D.M. Maurizi, A.M. Montanini, G.J. Chaparro, J.P. Stagnaro, A. Romani, A.C. Bianchi, G. Álvarez, A. Palaoro, M. Bernan, R. Cabrera-Montesino, C. Domínguez, C.G. Rodríguez, C.G. Silva, E. Bogdanowicz, F.O. Riera, G. Benchetrit, I. Perez, J. Vimercati, L.S. Marcos, L. Ramasco, M. Caridi, M.C. Oyola, M.C. Rodríguez, M.L. Spadaro, M.S. Olivieri, P. Saul, P.D. Juarez, R.H. Pérez, P. Botta, D.Q. Quintana, A.M. Ríos, V. Chediack, W. Chilon, Ameena Isa Alsayegh, Fatema Hasan Yaseen, Lateefa Fardan Hani, Saleh Fakher Sowar, Tahira Anwar Magray, E.A. Medeiros, A. Alves De Oliveira, A. Romario-Mendes, C. Fernandes-Valente, C. Santos, D. Escudeiro, D. Azevedo-Ferreira Lima, D. Azevedo-Pereira, E.M. Onzi-Siliprandi, F. Serpa-Maia, F. Aguiar-Leitao, G. Assuncao-Ponte, J. Dos Anjos-Lima, J. Olszewski, K. Harten Pinto Coelho, L.F. Alves De Lima, M. Mendonca, M.L. Maciel-Canuto Amaral, M.T. Tenorio, S. Gerah, M. Andrade-Oliveira-Reis, M. Moreira, M. Ximenes-Rocha Batista, R.S. Campos-Uchoa, R. Rocha-Vasconcelos Carneiro, R. Amaral De Moraes, S.C. Do Nascimento, T. Moreira-Matos, T.M. Lima-De Barros Araujo, T. De Jesus Pinheiro-Bandeira, V.L. Machado-Silva, W.M. Santos Monteiro, E. Hristozova, E.D. Kostadinov, K. Angelova, V.A. Velinova, V.J. Dicheva, X. Guo, G. Ye, R. Li, L. Song, K. Liu, T. Liu, G. Song, C. Wang, X. Yang, H. Yu, Y. Yang, A. Martínez, A.R. Vargas-García, A. Lagares-Guzmán, A.P. González, C. Linares, C. Ávila-Acosta, D. Santofimio, D. Yepes-Gomez, D.A. Marin-Tobar, D.P. Mazo-Elorza, E.G. Chapeta-Parada, G. Camacho-Moreno, G.E. Roncancio-Vill, I.A. Valderrama-Marquez, J.E. Ruiz-Gallardo, J.O. Ospina-Martínez, J. Osorio, J.I. Marín-Uribe, J.C. López, S. Gualtero, J.R. Rojas, K. Gomez-Nieto, L.Y.M. Rincon, L. Meneses-Ovallos, L.M. Canas-Giraldo, L.D. Burgos-Florez, M. Amaral-Almeida Costa, M. Rodriguez, N. Barahona-Guzmán, O. Mancera-Paez, P.A. Rios-Arana, R. Ortega, S.L. Romero-Torres, S.M. Pulido-Leon, S. Valderrama, V.M. Moreno-Mejia, W. Raigoza-Martinez, W. Villamil-Gomez, Y.A. Pardo-Lopez, A. Argüello-Ruiz, A. Solano-Chinchilla, G.A. Muñoz-Gutierrez, I. Calvo-Hernández, L. Maroto-Vargas, M.A. Zuniga, M. Valverde-Hernandez, O. Chavarria-Ugalde, B. Herrera, C. Díaz, M.M. Bovera, C. Cevallos, C. Pelaez, E. Jara, V. Delgado, E.E. Coello-Gordon, F. Picoita, F.M. Guerrero-Toapant, F. Valencia, G. Santacruz, H. Gonzalez, L.N. Pazmino, M.F. Garcia, M. Arboleda, M. Lascano, N. Alquinga, V. Ramírez, Reham H.A. Yousef, Abd El Moniem Moustafa, A. Ahmed, A.M. Elansary, Ahmad Mahmoud Ali, Ahmed Hasanin, Antoine Abdel Messih, Arwa Ramadan, B.A. El Awady, D.M. Hassan, Doaa Abd El Aziz, Hala Hamza, Hala Mounir Agha, Islam Abdullorziz Ghazi, J. ElKholy, May Abdel Fattah, Mervat Elanany, M. Mansour, M.M.A. Haleim, R. Fouda, Rasha Hamed El-Sherif, S. Bekeit, V. Bayani, Y.S. Elkholy, Y.M. Abdelhamid, Zeinab Salah, D.M. Rivera, A. Chawla, A.N. Manked, A. Azim, A. Mubarak, A. Thakur, A.V. Dharan, A. Patil, A. Sasidharan, Anil Kumar Bilolikar, A. Anirban Karmakar, A.M. Mathew, Anuja Kulkarni, Anuradha Agarwal, Anuradha Sriram, A. Dwivedy, Arnab Dasgupta, A. Bhakta, Arul Rose Suganya, A. Poojary, Ashwin Kumar Mani, Asmita Sakle, Babu K. Abraham, Baby Padmini, B. Ramachandran, Banambar Ray, Basanta Kumar Pati, Bhaskar Narayan Chaudhury, Biraj Mohan Mishra, S. Biswas, M. Bri Saibala, Burhan Q. Jawadwala, C. Rodrigues, Chirag Modi, Chirag Patel, D.K. Khanna, Dedeepiya Devaprasad, Deepa Divekar, Deepesh G. Aggarwal, J.V. Divatia, Dolatsinh Zala, Edwin Pathrose, Fazil Abubakar, Felcy Chacko, G.S. Gehlot, Gautam Khanna, H.K. Sale, Indranil Roy, Jayant Shelgaonkar, Jehangir Sorabjee, Jincy Eappen, Justin Mathew, Jyotishka Pal, Karthikeya Varma, Kashmira Limaye Joshi, Kavita Sandhu, R. Kelkar, Lakshmi Ranganathan, L. Pushparaj, Madhav Lavate, Madhavi Latha, Madhupriya Suryawanshi, M. Bhattacharyya, Maithili Kavathekar, Manoj Kumar Agarwal, Mayur Patel, Mehul Shah, M.N. Sivakumar, Mohit Kharbanda, Mrinmoy Bej, Mrunalini Potdar, M. Chakravarthy, M. Karpagam, S.N. Myatra, N. Gita, N.P. Rao, N. Sen, N. Ramakrishnan, N. Jaggi, N. Saini, N.K. Pawar, Nikhil Modi, Nirav Pandya, Nisith Mohanty, Pooja Thakkar, Pradnya Joshi, Prafulla Kumar Sahoo, Pravin Kumar Nair, Priyadarshini Senthil Kumar, Priyanka Patil, Purnima Mukherjee, P. Mathur, Purvi Shah, R. Sukanya, Rajalakshmi Arjun, Rajesh Chawla, Ram Gopalakrishnan, Ramesh Venkataraman, S. Raut, Ravikumar Krupanandan, Reshma Tejam, Richa Misra, Ritesh Debroy, S. Saranya, Sajith Narayanan, Sanghamitra Mishra, Sanjith Saseedharan, Sankar Sengupta, S.K. Patnaik, Saswati Sinha, Seelas Blessymole, Seema Rohra, Senthilkumar Rajagopal, Shanta Mukherjee, Sharmila Sengupta, Sheeba John, Shefali Bhattacharya, null Sijo, Sinchan Bhattacharyya, S. Singh, T. Sohanlal, Sonali Vadi, S.S. Dalal, S.K. Todi, Subodh Kumar, Sudha Kansal, Sudhjan Misra, Sudipta Bhattacharyya, Suhas Nirkhiwale, Sujit Kar Purkayastha, Sujoy Mukherjee, S. Sahu, Sunil Sharma, Suresh Kumar, S. Basu, S. Shetty, S. Shah, T. Singhal, Thara Francis, Thejasvini Anand, V. Venkateshwar, Valsa Thomas, V. Kothari, null Velupandi, Vini Kantroo, Gortap Sitohang, Retno Kadarsih, Anahita Sanaei, Behzad Maghsudi, Golnar Sabetian, Mansoor Masjedi, Masoud Alebouyeh, Somayeh Jahani Sherafat, Yassir Khidir Mohamed, Abdulrahim Al Khamis, Adnan Soliman Alsaadi, Ahmed Abdoh Al-Jarie, Aisha Hassan Mutwalli, A.S.K. Rillorta, Anumol Thomas, Ashraf Kelany, Athena Manao, Dhaffer Moghram Alamri, E.B. Santiago, E.P. Cruzpero, Fahad Ahmed Sawan, Fatima Abdullah Al Qasmah, Haeel Alabdaly, Hajer Am Al-Dossary, Hala Ahmed, Hala Roshdi, Halima Yahia Al-Alkami, Hana Hanafi, Hassan Eisa Ammari, Hatem Mohd Al Hani, Ibrahim A.M. Alzaydani Asiri, Jeffrey Asidera Mendoza, Jomol Philipose, Joy Ola Selga, null Kehkashan, Khalid Mohammed Ghalilah, Leide Shyrine Redito, L. Josph, M. Al-Alawi, Manal Mansour Al-Gethamy, Marjory Madco, M.G. Manuel, M. Girvan, Mervat Aldalaton, M. De Guzman, Modhi Alkhamaly, Mohammad Masfar, Mohammed Ahmed Ali Karrar, Munayfa Musallam Al Azmi, Myrna Lim Quisai, Myrna Misador Torres, N. Al-Abdullah, Nader Ahmed Tawfic, Nashwa Elsayed, Nawal Salah Abdulkhalik, Nehad Abdulshakour Bugis, Neilia Cardinal Ariola, N. Gad, Nesreen Alghosn, Nidal Tashkandi, N. Al Zharani, P.A. De Vera, Radhika Krishnan, Raed Hassan Al Shehri, Rasha Nour Aldeen Jaha, Reny Thomas, Rhea Lynn Cresencia, R. Penuliar, R.V. Lozada, S. Al Qahtani, Sameh Twfik, Sarah Hassan Al Faraj, Sherin El-Sherbiny, Siti Jhulmina B. Alih, Solita Briones, Syed Zahid Bukhari, Tariq Saad Abdulhadi Alotaibi, Uma Gopal, Usha Nair, Wael Abdulrahman Abdulatif, Waleed Mohd Hussain, Wynndale Mae Demotica, G. Spahija, N. Baftiu, A. Gashi, Abeer A. Omar, A.M. Mohamed, F.M. Rebello, Haifaa Hassan Almousa, Naglaa Mahmoud Abdo, S.M. George, Soad Khamis, Suja Thomas, A. Ahmad Zaatari, A. Anwar Al Souheil, H. Ayash, I. Zeid, J. Tannous, N.K. Zahreddine, R. Ahmadieh, T. Mahfouz, T. Kardas, V. Tanzi, Z. Kanafani, Z. Hammoud, A. Dagys, D. Grinkeviciute, R. Kevalas, T. Kondratas, Milena Petrovska, Katja Popovska, Zan Mitrev, Zaneta Bogoevska Miteva, Katerina Jankovska, Snezana Tufekcievska Guroska, Chin Seng Gan, Ainul Auzani Othman, Aliza Mohamad Yusof, Anis Siham Zainal Abidin, Fadzlina Abdul Aziz, Foong Kit Weng, Hasimah Zainol, Kamal Bashar Abu Bakar, Lucy Chai See Lum, Marzida Mansor, Mazuin Kamarul Zaman, Mohamad Fadhil Hadi Jamaluddin, Mohd Shahnaz Hasan, Raha Abdul Rahman, Rhendra Hardy Mohamad Zaini, Rosliza Zhazali, Sasheela Sri La Sri Ponnampala, Soo Lin Chuah, Wan Fadzlina Wan Mohd Shukeri, Wan Nazaruddin Wan Hassan, Wan Nurbayah Wan Yusoff, Wan Rahiza Wan Mat, M.A. Cureno-Diaz, G. Aguirre-Avalos, A. Flores-Alvarado, A. Cerero-Gudino, A. Zamores-Pedroza, B. Cano-Munoz, B.E. Hernandez-Chena, C.C. Carreon-Martinez, H. Coronado-Magana, F. Corona-Jimenez, E. Rodriguez-Noriega, E. Alcala-Martinez, E. Gonzalez-Diaz, F.M. Guerra-Infante, G. Arteaga-Troncoso, G. Martinez-Falcon, G. Leon-Garnica, H.A. Delgado-Aguirre, H.R. Perez-Gomez, I.E. Sosa-Gonzalez, J.A. Galindo-Olmeda, J.J. Ayala-Gaytan, J. Rodriguez-Pacheco, L. Zamorano-Flores, J.A. Lopez-Pulgarin, M.G. Miranda-Novales, M. Ramírez, M. Lopez-Hurtado, M. Lozano, M.E. Gomez, M.E. Sanchez-Castuera, M. Kasten-Monges, M. Gonzalez-Martinez, M. Sanchez-Vargas, M.C. Culebro-Burguet, M.A. Altuzar-Figueroa, J.C. Mijangos-Mendez, O.G. Ramires, O.S. Espinosa, R. De Leon-Escobedo, R. Salas-Flores, R. Ruiz-Rendon, S. Petersen-Morfin, S.A. Aguirre-Diaz, S. Esparza-Ahumada, S. Vega-Gonzalez, V. Gaona-Flores, V.A. Monroy-Colin, Z. Cruz-Rivera, A. Bat-Erdene, Batsaikhan Narankhuu, Batsuren Choijamts, Battsetseg Tuvdennyam, Byambadorj Batkhuu, K.H. Chuluunchimeg, D. Enkhtsetseg, G. Batjargal, G. Bayasgalan, M. Dorj, Naranpurev Mendsaikhan, Otgon Baatar, P. Suvderdene, S. Baigalmaa, T. Khajidmaa, Tsolmon Begzjav, null Tsuyanga, Z. Ariyasuren, A.A. Zeggwagh, K. Berechid, K. Abidi, N. Madani, R. Abouqal, Anjeela Koirala, Rashmi Giri, Samana Sainju, Subhash Prasad Acharya, Abeera Ahmed, Aun Raza, Azra Parveen, Faisal Sultan, Maria Khan, Nadeem Paul, Nargis Daud, Sana Yusuf, Summiya Nizamuddin, E. Garcia-Mayorca, E.G. Castaño, J.L. Moreno-Castillo, J.M. Ballinas-Aquino, L. Lara, M. Vargas, M.I. Rojas-Bonilla, S.J. Ramos, T. Mapp, V. De Iturrado, C.E. La Hoz Vergara, C.F. Linares-Calderon, D. Moreno, E. Ramirez, F.M. Ramírez Wong, G.M. Montenegro-Orrego, H.R. Sandoval-Castillo, J. Pichilingue-Chagray, J. Mueras-Quevedo, K.F. Aibar-Yaranga, L.I. Castillo-Bravo, L.M. Santivanez-Monge, M.J. Mayorga-Espichan, M.L.G. Rosario-Tueros, M.V. Changano-Rodriguez, N.E. Salazar-Ramirez, V.A. Marquez-Mondalgo, Anna Lyn N. Tajanlangit, Arnefelina S. Tamayo, Cristina Mari Jean P. Llames, Ever Labro, Ana P. Dy, J.D. Fortin, L.D. Bergosa, L.G. Salvio, V. Bermudez, M.C. Sg-Buenaflor, M.F. Trajano, M.T. Mendoza, O.P. Javellana, R.R. Maglente, Y. Arreza-Galapia, J.A. Navoa-Ng, A. Kubler, B. Barteczko-Grajek, B. Dragan, M. Zurawska, M. Mikaszewska-Sokolewicz, M. Zielinska, G.Y. Ramos-Ortiz, A. Florin-Rogobete, C. Daliborca Vlad, D. Muntean, D. Sandesc, M. Papurica, M. Licker, Ovidiu Horea Bedreag, R. Popescu, S.D. Grecu, V. Dumitrascu, A. Molkov, D. Galishevskiy, M. Furman, A. Simic, D. Lekic, G. Ristic, J. Eremija, J. Kojovic, L. Nikolic, M. Bjelovic, A. Lesnakova, S. Hlinkova, M.O. Gamar-Elanbya, Namphon Supa, Pornpheth Prasan, Rungratchanee Pimathai, Suthinee Wanitanukool, Suwara Somabutr, N. Ben-Jaballah, A. Borgi, A. Bouziri, A. Dilek, A. Oncul, A. Kaya, Ali Pekcan Demiroz, A. Gunduz, A. Ozgultekin, Asuman Inan, A.N. Yalcin, A. Ramazanoglu, A. Engin, A. Willke, Basak Ceyda Meco, C. Aygun, C. Bulut, C. Uzun, C. Becerik, Cigdem Ataman Hatipoglu, Cigdem Yildirim Guclu, D. Ozdemir, D. Yildizdas, D. Ugurcan, E. Azak, E. Guclu, Esmeray Mutlu Yilmaz, F. Sebnem-Erdinc, F. Sirmatel, F. Ulger, Ferhat Sari, Filiz Kizilates, G. Usluer, G. Ceylan, G. Ersoz, G. Kaya, Gunay Tuncer Ertem, G. Senol, Hasan Agin, Hatice Cabadak, H. Yilmaz, Hulya Sungurtekin, Humeyra Zengin, H. Turgut, I. Ozgunes, I. Devrim, I. Erdem, Inşa Gul Ekiz Işcanlı, M. Mehmet Bakir, M.F. Geyik, M. Oral, M. Meric, M. Cengiz, M. Ozcelik, M. Altindis, M. Sunbul, N. Elaldi, N. Kuyucu, N. Unal, N. Oztoprak, N. Yasar, Nurettin Erben, Nuri Bayram, Oguz Dursun, Oguz Karabay, O. Coskun, Ozden Ozgur Horoz, Ozge Turhan, Ozlem Sarac Sandal, Recep Tekin, Saban Esen, Selvi Yener Erdogan, Serhat Unal, Sevim Karacorlu, Suha Sen, Suzan Sacar, Volkan Yarar, Yeliz Oruc, Yusuf Sahip, Zeynep Kaya, Anamma Philip, Ashraf Elhoufi, Hussain Alrahma, E. Sachez, F. Perez, G.D. Empaire, H. Vidal, L. Montes-Bravo, M.E. Guzman Siritt, N. Orozco, N. Navarrete, Y. Ruiz, Z. Duran-Gil De Anez, Dang Thi Van Trang, Dao Quang Minh, Dao Xuan Co, Dinh Pham Phuong Anh, Le Thi Anh Thu, Le Thi Diem Tuyet, Le Thi Thu Nguyet, Ngo uy Chau, Nguyen Gia Binh, Nguyen Phuc Tien, Nguyen Quoc Anh, Phan Thi Hang, Tran Thi My Hanh, Tran Thi Thuy Hang, Truong Anh Thu, Vo Thi Hong Thoa, Ondokuz Mayıs Üniversitesi, and MERİÇ KOÇ, MELİHA

Subjects
Male, 0301 basic medicine, Pediatrics, Imipenem, Antibiotic resistance, Epidemiology, health care facilities, manpower, and services, Ceftazidime, Global Health, 0302 clinical medicine, Bloodstream infection, Prospective Studies, 030212 general & internal medicine, Child, Aged, 80 and over, Cross Infection, Urinary tract infection, Incidence, Health Policy, Ventilator-associated pneumonia, Middle Aged, Intensive Care Units, Infectious Diseases, Amikacin, Child, Preschool, Limited resources countries, Female, medicine.drug, Adult, medicine.medical_specialty, Adolescent, Health care-associated infection, 030106 microbiology, Catheter-associated urinary tract infection, Developing countries, Young Adult, 03 medical and health sciences, Intensive care, medicine, Humans, Hospital infection, Aged, business.industry, Infant, Newborn, Public Health, Environmental and Occupational Health, Infant, Device use, Nosocomial infection control, medicine.disease, Emergency medicine, Central line-associated bloodstream infections, business
Abstract

Hasan, M. Shahnaz/0000-0002-7493-7416; Abouqal, Redouane/0000-0002-6117-4341; Altindis, Mustafa/0000-0003-0411-9669; Masjedi, Mansoor/0000-0001-6175-9289; Popescu, Roxana/0000-0002-9387-1141; Mikaszewska-Sokolewicz, Malgorzata A/0000-0002-1148-7817; Meco, Basak Ceyda/0000-0003-2951-9634; Kumar, Perikala Vijayananda/0000-0001-8315-7000; Zand, Farid/0000-0003-3489-3372; Maghsoudi, Behzad/0000-0002-1279-8799; KAMARUL ZAMAN, MAZUIN/0000-0002-7920-6399; Gan, Chin Seng/0000-0002-6758-4798; Horoz, Ozden Ozgur/0000-0001-7590-650X; Medeiros, Eduardo A/0000-0002-6205-259X; Sabetian, Golnar/0000-0001-8764-2150; UNAL, SERHAT/0000-0003-1184-4711; Gan, Chin Seng/0000-0002-6758-4798; Delia, Muntean/0000-0001-9100-4530; Yalcin, Ata Nevzat/0000-0002-7243-7354; Leblebicioglu, Hakan/0000-0002-6033-8543; Horhat, Florin George/0000-0001-6133-0204; Yousef, Reham H. A./0000-0003-4004-3008; Delgado Aguirre, Hector Alberto/0000-0001-5448-7975; El Kholy, Amani/0000-0002-0645-7664; Rodriguez Ferrer, Marena Luz/0000-0002-8053-8454; Sanaei Dashti, Anahita/0000-0002-2827-3575; KARABAY, OGUZ/0000-0003-1514-1685; Barahona G., Nayide/0000-0003-3559-6900; Stagnaro, Juan Pablo/0000-0003-3836-9957; Alexandru Florin, Rogobete/0000-0003-1286-4431; KAYA, ZEYNEP/0000-0002-8468-2103; Dragan, Barbara/0000-0003-3108-4211; alvarez Moreno, carlos Arturo/0000-0001-5419-4494; Gonzalez Martinez, Marisela del Rocio/0000-0003-1474-736X; Jayatilleke, Kushlani/0000-0002-3931-6630; Unal, Necmettin/0000-0002-9440-7893; Duszynska, Wieslawa/0000-0002-5880-4904; Ngo, Quy Chau/0000-0002-6787-2757; Elmanakhly, Arwa/0000-0001-8557-0536; yildizdas, dincer/0000-0003-0739-5108; Kanj, Souha/0000-0001-6413-3396; Gupta, Umesh/0000-0001-7717-1404 WOS: 000392626300014 PubMed: 27742143 Background: We report the results of International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2010-December 2015 in 703 intensive care units (ICUs) in Latin America, Europe, Eastern Mediterranean, Southeast Asia, and Western Pacific. Methods: During the 6-year study period, using Centers for Disease Control and Prevention National Healthcare Safety Network (CDC-NHSN) definitions for device-associated health care-associated infection (DAHAI), we collected prospective data from861,284 patients hospitalized in INICC hospital ICUs for an aggregate of 3,506,562 days. Results: Although device use in INICC ICUs was similar to that reported from CDC-NHSN ICUs, DA-HAI rates were higher in the INICC ICUs: in the INICC medical-surgical ICUs, the pooled rate of central lineassociated bloodstream infection, 4.1 per 1,000 central line-days, was nearly 5-fold higher than the 0.8 per 1,000 central line-days reported from comparable US ICUs, the overall rate of ventilator-associated pneumonia was also higher, 13.1 versus 0.9 per 1,000 ventilator-days, as was the rate of catheterassociated urinary tract infection, 5.07 versus 1.7 per 1,000 catheter-days. From blood cultures samples, frequencies of resistance of Pseudomonas isolates to amikacin (29.87% vs 10%) and to imipenem (44.3% vs 26.1%), and of Klebsiella pneumoniae isolates to ceftazidime (73.2% vs 28.8%) and to imipenem (43.27% vs 12.8%) were also higher in the INICC ICUs compared with CDC-NHSN ICUs. Conclusions: Although DA-HAIs in INICC ICU patients continue to be higher than the rates reported in CDC-NSHN ICUs representing the developed world, we have observed a significant trend toward the reduction of DA-HAI rates in INICC ICUs as shown in each international report. It is INICC's main goal to continue facilitating education, training, and basic and cost-effective tools and resources, such as standardized forms and an online platform, to tackle this problem effectively and systematically. (C) 2016 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved. VDR; Foundation to Fight against Nosocomial Infections The funding for design, development, maintenance, technical support, data validation, and report generation of the Surveillance Online System, and the activities carried out at International Nosocomial Infection Control Consortium headquarters, were provided by VDR and the Foundation to Fight against Nosocomial Infections.

Published
2016

11. Usefulness of APACHE-II, SOFA, ISARIC/WHO 4C Mortality Score and CO-RADS for Mortality Prediction of Critically Ill Coronavirus Disease-2019 Patients

Author

Hülya Sungurtekin, Fatih Sargın, Metin Kılınç, Mithat Kahramanoğlu, Mert Akbulut, Ferruh Ayoğlu, Ahmet Çalışkan, and Simay Karaduman

Subjects
covid-19, intensive care, co-rads classification, 4c mortality score, sofa score, apache-ii score, Medicine, Internal medicine, RC31-1245, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Objective:It was aimed to report the Acute Physiology and Chronic Health Evaluation-II (APACHE-II) score, Sequential Organ Failure Assessment (SOFA) score, Glasgow coma scale (GCS), 4C mortality score and the coronavirus disease-2019 (COVID-19) Reporting and Data System (CO-RADS) in predicting the outcome of critically ill COVID-19 patients.Materials and Methods:Patients with laboratory-confirmed COVID-19 infection or clinical and radiological confirmed COVID-19 infection who were admitted to adult intensive care unit (ICU) were included. Clinical characteristics, outcomes, APACHE-II score, SOFA score, International Severe Acute Respiratory and Emerging Infections Consortium/World Health Organization 4C mortality score and CO-RADS classification were reported at admission.Results:Two hundred seventy six patients were included in this study. The mean age was higher in non-survivor patients. The most common cause of hospitalization was respiratory failure (67%). The common co-morbidities were hypertension (51.8%), cardiac disease (43.4%) and diabetes (33.6%). Organ failure was present in 61.5% of the patients. The mean APACHE-II, SOFA, GCS and 4C mortality scores were higher in non-survivor patients. 4C mortality and SOFA scores showed higher predictive accuracy for mortality with an area under the curve 0.736 and 0.706, respectively. 4C mortality had sensitivity of 78.9% and specificity of 58.1% whereas of SOFA had a sensitivity of 78.9% and a specificity of 53.3%.Conclusion:4C mortality and SOFA scores could be a predictors of mortality in COVID-19 patients in the ICU.

Published
2023
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12. Evaluation of the end stage patients in intensive care

Author

Hulya Sungurtekin and Semiha Yalcin

Subjects
medicine.medical_specialty, business.industry, Intensive care, Medicine, General Medicine, Emergency Nursing, Stage (cooking), Critical Care Nursing, business, Intensive care medicine
Published
2020

13. Potentially Inappropriate Treatments in Intensive Care Units (INAPPT-ICU): Point Prevalence Study

Author

Elif Erdoğan Öngel, Hülya Sungurtekin, Dilek Memiş, Demet Tok Aydın, Hilal Ayoğlu, Ferruh Ayoğlu, Işıl Özkoçak Turan, Çetin Kaymak, Dilek Özcengiz, Mustafa Kemal Bayar, and Yalım Dikmen

Subjects
terminal care, inappropriate treatments, intensive care units, advanced care planning, patient care planning, Medicine, Internal medicine, RC31-1245, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Objective: Technological advances increased prolonged life expectancy of the terminal patients, who had end-stage diseases. End-of-life care in intensive care units (ICU) has increased with the rise in admissions of terminal patients to ICU. Our aims in this study were to determine the prevalence of terminal patients, and to find the reasons for potentially inappropriate treatments in ICUs. Materials and Methods: It was nationwide, multicenter, point prevalence and observational study. All adult patients, who stayed more than 48 h in the ICU, were enrolled. All patients were recorded on an electronic case record form, consisting of data on patient demographics, treatments, family participation and mini survey for physicians. The study was conducted on October 15, 2018 with a follow-up for 30 days. Results: Of 1127 patients 286 (25%) ICU patients were diagnosed as terminal patients by ICU physicians depending on primary physician statement. Terminal patients relatives requests and physicians legal concerns reduced end-of-life care quality. Terminal patients had significantly increased usage of mechanical ventilation, inotropic drugs, and poor end-of-life care quality (p

Published
2022
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14. Creutzfeldt-Jakob Disease After the Coronavirus Disease-2019 Vaccination

Author

Anıl Kuvandık, Ecenur Özcan, Simay Karaduman, and Hülya Sungurtekin

Subjects
covid-19, vaccine, creutzfeldt-jakob disease, prion protein, Medicine, Internal medicine, RC31-1245, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Reports of neurological problems are increasing for the clinical presentation of coronavirus disease-2019 (COVID-19). The clinical presentation reported in this study seemed to be a combination of nonspecific complications of the systemic disease, inflammation of the cerebrovascular system, and the effects of a direct viral infection. Creutzfeldt-Jakob disease, a spongiform encephalopathy caused by prions, is characterized by a severe neurological destruction, which has an extremely high mortality. In this publication, we presented a patient who was admitted to the Pamukkale University Anesthesiology Intensive Care Units with the neurological findings that developed after the COVID-19 vaccine (CoronaVac, Sinovac Life Sciences, Beijing, China). The patient died due to the progressive neurological disorders. In cases where rapidly progressive neurological disorders are observed, Creutzfeldt-Jakob disease should be considered and the role of immunity-related conditions in the progression of the disease should be investigated.

Published
2022
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15. Evaluation of the Prognosis of Cancer Patients Treated in Intensive Care Units

Author

Gökhan Kılınç, Simay Karaduman, and Hülya Sungurtekin

Subjects
cancer, intensive care unit, prognosis, Medicine, Internal medicine, RC31-1245, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Objective:The number of cancer cases and mean life expectancy are increasing with improvements in diagnosis and treatment options. This increase creates the need for intensive care units (ICUs) for cancer patients. This study aimed to determine the risk factors associated with admission of cancer patients to the ICU, intensive care prognosis, and mortality rates and cost per patient.Materials and Methods:In this study, we analyzed the data of cancer patients who were followed up in Pamukkale University Faculty of Medicine, Anesthesiology ICU. The variables that were analyzed included intensive care prognosis, mortality rates, risk factors affecting mortality, and cost per patient. ICU patient’s folders, epicrisis reports, and follow-up documents of 251 patients with solid or systemic malignancies who were admitted to the ICU of Pamukkale University Faculty of Medicine, Anesthesiology Department for a period of two-years were analyzed.Results:The most common reason for admission to ICU for patients with solid or systemic malignancies was respiratory failure 63.34% (n=159) followed by sepsis 16.33% (n=41) and cardiac arrest 5.17% (n=13). According to the cancer staging of the patients, 58.5% (n=147) were classified as stage 4 and 16.3% (n=41) as stage 3. The cost per patient per day in the ICU ranged from 186.86 Turkish Liras (TL) to 4407.39 TL and the mean cost was 1628.49±524.12 TL. The mortality rate among these cancer patients was 89.2%.Conclusion:Most of the cancer patients died in the ICU with high medical expenses. When patients are evaluated for admission to the ICU, the patient’s primary physician and ICU physician should reach a consensus as to whether the patient is in a terminal condition or not and whether palliative care should be administered to them.

Published
2022
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16. International Nosocomial Infection Control Consortium (INICC) report, data summary of 43 countries for 2007-2012. Device-associated module

Author

Víctor Daniel Rosenthal, Dennis George Maki, Yatin Mehta, Hakan Leblebicioglu, Ziad Ahmed Memish, Haifaa Hassan Al-Mousa, Hanan Balkhy, Bijie Hu, Carlos Alvarez-Moreno, Eduardo Alexandrino Medeiros, Anucha Apisarnthanarak, Lul Raka, Luis E. Cuellar, Altaf Ahmed, Josephine Anne Navoa-Ng, Amani Ali El-Kholy, Souha Sami Kanj, Ider Bat-Erdene, Wieslawa Duszynska, Nguyen Van Truong, Leonardo N. Pazmino, Lucy Chai See-Lum, Rosalia Fernández-Hidalgo, Gabriela Di-Silvestre, Farid Zand, Sona Hlinkova, Vladislav Belskiy, Hussain Al-Rahma, Marco Tulio Luque-Torres, Nesil Bayraktar, Zan Mitrev, Vaidotas Gurskis, Dale Fisher, Ilham Bulos Abu-Khader, Kamal Berechid, Arnaldo Rodríguez-Sánchez, Florin George Horhat, Osiel Requejo-Pino, Nassya Hadjieva, Nejla Ben-Jaballah, Elías García-Mayorca, Luis Kushner-Dávalos, Srdjan Pasic, Luis E. Pedrozo-Ortiz, Eleni Apostolopoulou, Nepomuceno Mejía, May Osman Gamar-Elanbya, Kushlani Jayatilleke, Miriam de Lourdes-Dueñas, Guadalupe Aguirre-Avalos, Diego Marcelo Maurizi, Adriana Montanini, Maria Laura Spadaro, Lorenzo Santiago Marcos, Priscila Botta, Florencia Maria Jerez, Maria Constanza Chavez, Lucia Ramasco, Maria Isabel Colqui, Maria Silvia Olivieri, Ana Silvia Rearte, Gladys Edith Correa, Paola Deolinda Juarez, Paola Fabiana Gallardo, Miriam Patricia Brito, Gabriel Horacio Mendez, Julia Rosa Valdez, Lorena Paola Cardena, Jose Maria Harystoy, Gustavo Jorge Chaparro, Claudia Gabriela Rodriguez, Rodolfo Toomey, Maria Caridi, Monica Viegas, Marisa Liliana Bernan, Adriana Romani, Claudia Beatriz Dominguez, Luis Kushner Davalos, Rosana Richtmann, Camila Almeida Silva, Tatiane T. Rodrigues, Amaury Mielle Filho, Ernandi Dagoberto Seerig Palme, Aline Besen, Caroline Lazzarini, Caroline Batista Cardoso, Francisco Kennedy Azevedo, Ana Paula Fontes Pinheiro, Aparecida Camacho, Braulio Matias De Carvalho, Maria Jose Monteiro De Assis, Ana Paula Vasconcelos Carneiro, Maria Lilian Maciel Canuto, Keyla Harten Pinto Coelho, Tamiris Moreira, Agamenon Alves Oliveira, Marcela Maria Sousa Colares, Marcia Maria De Paula Bessa, Tereza De Jesus Pinheiro Gomes Bandeira, Renata Amaral De Moraes, Danilo Amâncio Campos, Tânia Mara Lima De Barros Araújo, Maria Tereza Freitas Tenório, Simone Amorim, Manuela Amaral, Julianne Da Luz Lima, Lindalva Pino Da Silva Neta, Caphiane Batista, Fabio Jorge De Lima Silva, Maria C. Ferreira De Souza, Katia Arruda Guimaraes, Julia Marcia Maluf Lopes, Karina M. Nogueira Napoles, Lorena Luiza Silva Neto Avelar, Lilian Aguiar Vieira, Luis Gustavo De Oliveira Cardo, Christianne F.V. Takeda, Glaydson A. Ponte, Fco Eduardo Aguiar Leitão, Ricardo De Souza Kuchenbecker, Rodrigo Pires Dos Santos, Erci Maria Onzi Siliprandi, Luiz Fernando Baqueiro Freitas, Ianick Souto Martins, Daiane Casi, Maria Angela Maretti Da Silva, Sergio Blecher, Margarete Villins, Reinaldo Salomao, Solange Regina Oliveira Castro, Daniela V. Da Silva Escudero, Mariana Andrade Oliveira Reis, Marcelo Mendonca, Valter Furlan, Antonio Claudio do Amaral Baruzzi, Tarquino Eristidesg Sanchez, Marina Moreira, Wania Vasconcelos de Freitas, Leonardo Passos de Souza, Velmira Angelova Velinova, Michael M. Petrov, Dimitar Georgiev Karadimov, Emil D. Kostadinov, Violeta Jivkova Dicheva, Chaohua Wang, Xiuqin Guo, Xihua Geng, Shufang Wang, Jinzhi Zhang, Ling Zhu, Shufang Zhuo, Chunli Guo, Tao Lili, Li Ruisheng, Liu Kun, Xuesong Yang, Li Yimin, Mao Pu, Li Changan, Yiang Shumei, Wu Kangxiong, Lin Meiyi, Guxiang Ye, Xu Ziqin, Suo Yao, Song Liqiang, Luis Marino Cañas Giraldo, Elsa Margarita Trujillo Ramirez, Paola Andrea Rios, Juan Carlos Torres Millan, Edwin Giovanny Chapeta Parada, Andres Eduardo Mindiola Rochel, Andres H. Corchuelo Martinez, Ana Marãa Perez Fernandez, Nayide Barahona Guzman, Alfredo Lagares Guzman, Marena Rodriguez Ferrer, Yazmin Leon Vega, Heidi Johanna Munoz, Germán Camacho Moreno, Sandra Liliana Romero Torres, Herlidia Taboada Hernandez, Ismael A. Valderrama MarquezClaudia Linares, Monica Espinosa Valencia, Lusayda Sanchez Corrales, Sandra Milena Bonilla, Jorge Ivan Marin Uribe, David Yepes Gomez, Javier Ospina Martinez, Luz Dary Burgos Florez, Johanna Osorio, Dagoberto Santofimio, Lorena Matta Cortes, Wilmer Villamil-Gomez, Gabriel Munoz Gutierrez, Adela Arguello Ruiz, Carlos Gonzalez Fuentes, Antonio Solano Chinchilla, Ivar Calvo Hernandez, Olber Chavarria Ugalde, Humberto Guanche Garcell, Clara Morales Perez, Selin Bardak, Sumru Ozkan, Nepomuceno Mejia, Adrian M. Puello Guerrero Glenny Mirabal, Margarita Delgado, Ramona Severino, Eliesel Lacerda, Gilda Tolari, María Marcela Bovera, Diego Barahona Pinto, Pedro Fernández González, Gasdali Santacruz, Nelly Alquinga, Celso Zaruma, Nelson Remache, Diego Morocho, Mario Arboleda, Mario Cadena Zapata, Maria Fernanda Garcia, Fabricio Picoita, Jorge Velez, Marcia Valle, Estuardo Salgado Yepez, Diego Morocho Tutillo, Ricardo Arteaga Mora, Andrea Peña Padilla, Mayra Chango, Karina Cabezas, Shirley Tenorio López, Ana Lucía Bonilla Escudero, Gladys Tatiana Sánchez, Hugo Alberto Gonzalez Flores, Islam Abdullorziz Ghazi, Mohamed Hassan, Ghada A. Ismail, Reham Hamed, Mona Mohiedden Abdel-Halim, May Abd El-Fattah, Doaa Abdel-Aziz, Zeinab Salah Seliem, Rasha Hamed Elsherif, Reham Ali Dewdar, Abeer Ahmed Mohmed, Lamiaa Abdel-Fatteh Ahmed, Lilian De Jesus Machuca, Concepcion Bran De Casares, Prokopis Kithreotis, Maria Daganou, Dimitrios Veldekis, Maria Kartsonaki, Achilleas Gikas, Marco Tulio Luque Torres, Denis Padgett, Doris Maribel Rivera, Namita Jaggi, Camilla Rodrigues, Bhagyesh Shah, Keyur Parikh, Jigar Patel, Riya Thakkar, Murali Chakravarthy, B.N. Gokul, R. Sukanya, Leema Pushparaj, Thejas Vini, Sukanya Rangaswamy, Saroj Kumar Patnaik, Vempati Venkateshwar, Biju John, Shamsher Dalal, Suneeta Sahu, Samir Sahu, Banambar Ray, Sudhiranjan Misra, Nisith Mohanty, Biraj Mohan Mishra, Prafulla Sahoo, Naresh Parmar, Sanghamitra Mishra, Basanta Kumar Pati, Santosh Singh, Bhabani Shankar Pati, Aparajita Panda, Swarna Banergee, Dipankar Padhihari, Soumya Samal, Karthikeya Varma, Velu Pandi Suresh Kumar, Ram Gopalakrishnan, Nagarajan Ramakrishnan, Babu Kuruvilla Abraham, Senthilkumar Rajagopal, Ramesh Venkatraman, Ashwin Kumar Mani, Dedeepiya Devaprasad, Lakshmi Ranganathan, Thara Francis, Kotturathu Mammen Cherain, Bala Ramachandran, Ravikumar Krupanandan, S. Muralidharan, Murali Karpagam, Baby Padmini, S. Saranya, Siva Kumar, Nirav Pandya, Rajesh Kakkar, Tenzin Zompa, Narinder Saini, Srinivas Samavedam, Ganshyam Jagathkar, Suhas Nirkhiwale, G.S. Gehlot, Shefali Bhattacharya, Sanjeev Sood, Suman Singh, Sanjeev Singh, Subhash Kumar Todi, Mahuya Bhattacharyya, Arpita Bhakta, Susmita Basu, Anuradha Agarwal, Manoj Agarwal, Mohit Kharbanda, Sankar Sengupta, Anirban Karmakar, Debkishore Gupta, Ajoy Krishna Sarkar, Rimita Dey, Chandramouli Bhattacharya, Mammen Chandy, V.R. Ramanan, Aseem Mahajan, Manas Roy, Sanjay Bhattacharya, Saswati Sinha, Indranil Roy, Umesh Gupta, Sujoy Mukherjee, Mrinmoy Bej, Purnima Mukherjee, Sumana Baidya, Afzal Azim, Asmita Sagar Sakle, Jehangir Soli Sorabjee, Mrunalini Subhash Potdar, Vaibhavi R. Subhedar, F.E. Udwadia, Hena Francis, Arpita Dwivedy, Sheena Binu, Suvin Shetty, Pravin Kumar Nair, Devendra K. Khanna, Felcy Chacko, Seelas Blessymole, Preeti Rajeev Mehta, Tanu Singhal, Sweta Shah, Vatsal Kothari, Reshma Naik, Mayur Harshadrai Patel, Deepesh Gokulchand Aggarwal, Burhanuddin Qutbuddin Jawadwala, Niketa Kaul Pawar, Shoeb Nizamuddin Kardekar, Abizer Nuruddin Manked, S.N. Myatra, J.V. Divatia, R. Kelkar, S.K. Biswas, V. Raut, S. Sampat, Alka Thool, Anil Karlekar, Sumi Nandwani, Sudhir Gupta, Sanjay Singhal, Madhu Gupta, Purva Mathur, Subodh Kumar, Kavita Sandhu, Arnab Dasgupta, Abhijeet Raha, Padmalatha Raman, Ashoo Wadhera, Binesh Badyal, Sarika Juneja, Bikas Mishra, Sunil Sharma, Megha Mehrotra, Jayant Shelgaonkar, Vikram Padbidri, Rohini Dhawale, Sheena Mary Sibin, Dileep Mane, Hanamant Kashinath Sale, Mohammad Mukhit Abdul Gaffar Kazi, Supriya Chabukswar, Anju Mathew, Dipti Gaikwad, Amol Harshe, Gita Nadimpalli, Sunil Bhamare, Soniya Thorat, Omnarayan Sarda, Pattabhiramarao Nadimpalli, Angelina Mendonca, Sujata Malik, Asmita Kamble, Nilakshi Kumari, Sohini Arora, Nita Munshi, Deepa Ganesh Divekar, Maithili Satish Kavathekar, Anuja Kedar Kulkarni, Madhupriya Vijay Suryawanshi, Madhavi Latha Bommala, Anil Bilolikar, Kashmira Limaye Joshi, Charulata Pamnani, Harvinder Wasan, Sonali Khamkar, Leena Steephen, Arjun Rajalakshmi, Anzar Thair, Aisha Mubarak, Swathy Sathish, Suresh Kumar, H. Sunil, Sujith Sujith, null Dinesh, Nagamani Sen, Nitin Shinde, Masoud Alebouyeh, Somayeh Jahani-Sherafat, Mohammad Reza Zali, Mohammad Reza Sarbazi, Nahid Mansouri, Elahe Tajeddin, Maryam Razaghi, Simasadat Seyedjavadi, Marjan Rashidan, Mansoor Masjedi, Behzad Maghsudi, Golnar Sabetian, Anahita Sanaei, Atefeh Yousefipour, Abdullah Mufareh Assiri, Elaine Mari Furukawa-Cinquini, Areej Dhafer Alshehri, Alysia Faye Giani, Nadia Lynette Demaisip, Elizabeth Laungayan Cortez, Analen Fabros Cabato, Jerlie Mae Gonzales Celiz, Ibrahim A.M. Al-Zaydani Asiri, Yassir Khidir Mohammed, Mohammed Abdullah Al Raey, Ali Omer Abdul Aziz, Saeed Ali Al Darani, Misbah Rehman Aziz, Roaa Hasan Basri, Duaa Khalil Al-Awadi, Syed Zahid Bukhari, Rosita Gasmin Aromin, Evangelina Balon Ubalde, Apsia Musa Molano, Hessa Abdullah Al Enizy, Celia Flores Baldonado, Fatima Mohammad Al Adwani, Arlu Marie Casuyon Pahilanga, Avigail M. Tan, Sonia Joseph, Deepa Sasidharan Nair, Nabeela Abdullah Al-Abdullah, Grace Sindayen, Annalyn Amor Malificio, Diaa Abdullah Mohammed, Hanan Mesfer Al Ghamdi, Ameurfina Curioso Silo, Marianina Brenda V. Valisto, Nektarios Foteinakis, Sameeh Salem Ghazal, Mercy V. Joseph, Ahmed Hakawi, Antigona Hasani, Ismet Jusufi, Gazmend Spahija, Nehat Baftiu, Agreta Gecaj-Gashi, Nasser Yehia Aly, Mohammad El-Dossoky Noweir, Suga Thomas Varghese, Ruby Jose Ramapurath, Amna Mostafa Mohamed, Sneha Mary George, Anu Kurian, Amani Fouad Sayed, Mona Foda Salama, Abeer Aly Omar, Flavie Maria Rebello, Dennis Malungcot Narciso, Nada Kara Zahreddine, Zeina Kanafani, Tala Kardas, Bassel Molaeb, Lamia Jurdi, Anwar Al Souheil, Mohamad Ftouni, Hasan Ayash, Tahsine Mahfouz, Tomas Kondratas, Dovile Grinkeviciute, Rimantas Kevalas, Greta Gailiene, Algirdas Dagys, Milena Petrovska, Katja Popovska, Zaneta Bogoevska-Miteva, Katerina Jankovska, Snezana Tufekcievska Guroska, Tanja Anguseva, Wan Nurbayah Wan Yusoff, Anis Shiham Zainal Abidin, Chin Seng Gan, Hasimah Zainol, Vineya Rai, Wong Kang Kwong, Mohd Shahnaz Hasan, Sasheela Sri La Sri Ponnampala, Jeyaganesh Veerakumaran, Ojan Assadian, Doan Mai Phuong, Nguyen Gia Binh, Kerinjeet Kaur, Joelene Lim, Lian-Huat Tan, Jegathesan Manikavasagam, Yuet-Meng Cheong, Hilario Coronado Magaña, Julio Cesar Mijangos Méndez, Federico Corona Jiménez, Sergio Esparza-Ahumada, Rayo Morfin-Otero, Eduardo Rodriguez-Noriega, Susana Gutierrez-Martinez, Hector Raul Perez-Gomez, Gerardo León-Garnica, Christian Mendoza-Mujica, Martha Cecilia Culebro Burguet, Jorge Horacio Portillo-Gallo, Fernando Aguilera Almazán, Gaspar Iglesias Miramontes, Maria del Rosario Vázquez Olivas, Lucio Alberto Aguilar Angel, Marisol Sanchez Vargas, Angel Orlando Flores Alvarado, Roberto Carlos Mares Morales, Luis Carlos Fernandez Alvarez, Hector Armando Rincon Leon, Karla Reyna Navarro Fuentes, Yuri Mariela Perez Hernandez, Gabriela Martinez Falcon, Angel Gonzalez Vargas, Marco A. Trujillo Juarez, Antonio Martinez Mulia, Paulina Alma Ulloa Camacho, Martha Y. Martinez-Marroquin, Marco Montell Garcia, Araceli Martinez Martinez, Elena Leon Sanchez, Guadalupe Gomez Flores, Marisela del Rocío González Martínez, Jesús Alfonso Galindo Olmeda, Georgina Olivarez, Enrique Barbachano Rodriguez, María Magdalena Gutierrez Castillo, María Guadalupe Villa González, Isaura Beatriz Sauceda Castañeda, Jaime Martínez Rodriguez, Otgon Baatar, Byambadorj Batkhuu, Kabiri Meryem, Barkat Amina, Rédouane Abouqal, Amine Ali Zeggwagh, Tarek Dendane, Khalid Abidi, Naoufel Madani, Syed Faisal Mahmood, Badaruddin A. Memon, Gul Hassan Bhutto, Nadeem Paul, Azra Parveen, Aun Raza, Amjad Mahboob, Summiya Nizamuddin, Faisal Sultan, Hammad Nazeer, Ashraf Ali Khan, Arifa Hafeez, Lydia Lara, Trudell Mapp, Balkys Alvarez, Magda Ivonne Rojas-Bonilla, Elizabeth Castano, Daisy A. De Moros, Roberto Espinoza Atarama, Maria Elena Calisto Pazos, Alfredo Paucar, Marlene Tasayco Ramos, Jenny Jurado, Dafne Moreno, Marãa E. Cruz Saldarriaga, Eliza Ramirez, Carlos Enrique La Hoz Vergara, Walter Enrique Prudencio Leon, Luis Isidro Castillo Bravo, Katya Fernanda Aibar Yaranga, Janet E. Pichilingue Chagray, Vanessa A. Marquez Mondalgo, Socorro Torres Zegarra, Nazario Silva Astete, Francisco Campos Guevara, Javier Soto Pastrana, Carlos F. Linares Calderon, Manuel Jesus Mayorga Espichan, Luis Martin Santivanez Monge, Maria V. Changano Rodriguez, Zoila Rosa Diaz Tavera, Fernando Martin Ramirez Wong, Selene Manga Chavez, Teodora Atencio-Espinoza, Victoria D. Villanueva, Maria Teresa Blanco-Abuy, Arnefelina S. Tamayo, Lailane D. Bergosa, Cristina Mari Jean P. Llames, Marilou F. Trajano, Suzette A. Bunsay, Jessica C. Amor, Regina Berba, Maria Carmen Sg Buenaflor, Ever Labro, Myrna T. Mendoza, Ofelia P. Javellana, Lilibeth G. Salvio, Rhoda Gay Rayco, Vanessa Bermudez, Andrzej Kubler, Marzena Zielinska, Magdalena Kosmider-Zurawska, Barbara Barteczko-Grajek, Ewa Szewczyk, Barbara Dragan, Malgorzata Anna Mikaszewska-Sokolewicz, Tomasz Lazowski, Elsie Cancel, Monica Sorina Licker, Liliana Alina Dragomirescu, Victor Dumitrascu, Dorel Sandesc, Ovidiu Bedreag, Marius Papurica, Delia Muntean, Igor Kotkov, Vladimir Kretov, Vladimir Shalapuda, Alexander Molkov, Sergey Puzanov, Ivan Utkin, Alexander Tchekulaev, Valentina Tulupova, Ljubica Nikolic, Goran Ristic, Jelena Eremija, Jelena Kojovic, Dragana Lekic, Sladjana Vasiljevic, Anna Lesnakova, Alzbeta Marcekova, Katarina Furova, May Osman Gamar Elanbya, Malik Abdo Ali, Shobhana Kumari Kadankunnel, Suwara Somabutr, Rungratchanee Pimathai, Suthinee Wanitanukool, Montri Luxsuwong, Namphon Supa, Pornpheth Prasan, Visanu Thamlikitkul, Silom Jamulitrat, Nonglak Suwalak, Parichart Phainuphong, Bouziri Asma, Borgi Aida, Bel Hadj Sarra, Khaldi Ammar, Gunay Tuncer Ertem, Cemal Bulut, Cigdem Ataman Hatipoglu, Fatma Sebnem Erdinc, Ali Pekcan Demiroz, Menekse Ozcelik, Basak Ceyda Meco, Mehmet Oral, Necmettin Unal, Cigdem Yildirim Guclu, Tanıl Kendirli, Erdal İnce, Ergin Çiftçi, Ayhan Yaman, Çağlar Ödek, Adem Karbuz, Bilge Aldemir Kocabaş, Nilgün Altın, Salih Cesur, Begum Atasay, Omer Erdeve, Hasan Akduman, Dilek Kahvecioglu, Ufuk Cakir, Duran Yildiz, Atila Kilic, Saadet Arsan, Dilek Arman, Serhat Unal, Yasemin Gelebek, Humeyra Zengin, Suha Sen, Hatice Cabadak, Ayse Erbay, Ata Nevzat Yalcin, Ozge Turhan, Melike Cengiz, Oguz Dursun, Perihan Gunasan, Sehnaz Kaya, Atilla Ramazanoglu, Cemal Ustun, Aliye Yasayacak, Hayrettin Akdeniz, Fatma Sirmatel, Ali Metin Otkun, Suzan Sacar, Alper Sener, Huseyn Turgut, Hulya Sungurtekin, Dogaç Ugurcan, Ceyda Necan, Cansu Yilmaz, Davut Ozdemir, Mehmet Faruk Geyik, Nevin Ince, Ayse Danis, Selvi Yener Erdogan, Nurettin Erben, Gaye Usluer, Ilhan Ozgunes, Cengiz Uzun, Oral Oncul, Levent Gorenek, Hakan Erdem, Orhan Baylan, Asu Ozgultekin, Asuman Inan, Sibel Bolukcu, Gunes Senol, Halil Ozdemir, Zeynel Gokmen, Sonay Incesoy Ozdemir, Ali Kaya, Gulden Ersoz, Necdet Kuyucu, Sevim Karacorlu, Zeynep Kaya, Ertugrul Guclu, Gulsume Kaya, Oguz Karabay, Saban Esen, Canan Aygun, Fatma Ulger, Ahmet Dilek, Hava Yilmaz, Mustafa Sunbul, Aynur Engin, Mehmet Bakir, Nazif Elaldi, Iftihar Koksal, Dincer Yildizdas, Ozden Ozgur Horoz, Ayşe Willke, Meliha Meriç Koç, Emel Azak, Naheed Elahi, Philip Annamma, Ashraf El Houfi, Maria Catalina Pirez Garcia, Hector Vidal, Fernando Perez, Gabriel D. Empaire, Yvis Ruiz, Dulce Hernandez, Dayana Aponte, Evelyn Salinas, Claudia Diaz, María Eugenia Guzmán Siritt, Zenaida Durán Gil De Añez, Luis Montes Bravo, Nelva Orozco, Eugenia Mejías, Nguyen Viet Hung, Nguyen Quoc Anh, Ngo Quy Chau, Truong Anh Thu, Le Thi Diem Tuyet, Dang Thi Van Trang, Vo Thi Hong Thoa, Nguyen Phuc Tien, Le Thi Anh Thu, Phan Thi Hang, Tran Thi My Hanh, Tran Thi Thuy Hang, Dinh Pham Phuong Anh, Ondokuz Mayıs Üniversitesi, KILIÇ, ATİLA, and MERİÇ KOÇ, MELİHA

Subjects
Imipenem, medicine.medical_specialty, Pediatrics, Low income countries, Asia, Epidemiology, Klebsiella pneumoniae, Health care-associated infection, Antibiotic resistance, Catheter-associated urinary tract infection, Ceftazidime, Network, Bloodstream infection, Developing countries, Nosocomial infection, Intensive care, medicine, Ventilator-associated pneumonia, Humans, Hospital infection, Prospective Studies, Urinary tract infection, Cross Infection, Infection Control, biology, business.industry, Health Policy, Public Health, Environmental and Occupational Health, medicine.disease, Nosocomial infection control, biology.organism_classification, Device-associated infection, United States, Europe, Pneumonia, Intensive Care Units, Infectious Diseases, Latin America, Amikacin, Emergency medicine, Africa, Limited resources countries, Central line-associated bloodstream infections, Centers for Disease Control and Prevention, U.S, business, medicine.drug
Abstract

Maghsoudi, Behzad/0000-0002-1279-8799; Kritsotakis, Evangelos/0000-0002-9526-3852; Yalcin, Ata Nevzat/0000-0002-7243-7354; Mikaszewska-Sokolewicz, Malgorzata A/0000-0002-1148-7817; ALDEMIR KOCABAS, Bilge/0000-0002-6396-5243; Masjedi, Mohammad Reza/0000-0002-6871-382X; Masjedi, Mansoor/0000-0001-6175-9289; Gan, Chin Seng/0000-0002-6758-4798; Oncul, Oral/0000-0002-1681-1866; Sabetian, Golnar/0000-0001-8764-2150; YAMAN, Ayhan/0000-0002-5651-1286; Ozdemir, Halil/0000-0002-7318-1688; Leon, Hector Armando Rincon/0000-0003-0715-200X; Delia, Muntean/0000-0001-9100-4530; Atasay, Fatma Begum/0000-0002-9114-5293; Zand, Farid/0000-0003-3489-3372; Kuchenbecker, Ricardo/0000-0002-4707-3683; Medeiros, Eduardo A/0000-0002-6205-259X; ROMERO LOPEZ-ALBERCA, CRISTINA/0000-0001-5856-8668; Salomao, Reinaldo/0000-0003-1149-4598; ozdemir, sonay incesoy/0000-0003-2863-901X; Meco, Basak Ceyda/0000-0003-2951-9634; Horoz, Ozden Ozgur/0000-0001-7590-650X; Horhat, Florin George/0000-0001-6133-0204; Kazi, Mohammad Mukhit/0000-0003-3824-5540; Ciftci, Ergin/0000-0002-4955-160X; Abouqal, Redouane/0000-0002-6117-4341; Leblebicioglu, Hakan/0000-0002-6033-8543; Garcell, Humberto Guanche/0000-0001-7279-0062; Kendirli, Tanil/0000-0001-9458-2803; de Souza, Maria Cecilia B V/0000-0003-0318-3087; Sanaei Dashti, Anahita/0000-0002-2827-3575; UNAL, SERHAT/0000-0003-1184-4711; alvarez Moreno, carlos Arturo/0000-0001-5419-4494; Barahona G., Nayide/0000-0003-3559-6900; Rodriguez Ferrer, Marena Luz/0000-0002-8053-8454; Karabay, Oguz/0000-0003-0502-432X; Kaya, Sehnaz/0000-0003-0002-1517; ERDEVE, OMER/0000-0002-3193-0812; Gonzalez Martinez, Marisela del Rocio/0000-0003-1474-736X; Gikas, Achilleas/0000-0002-8455-9631; Baylan, Orhan/0000-0002-6529-7824; Mitrev, Zan/0000-0001-7859-8821; yildizdas, dincer/0000-0003-0739-5108; Ngo, Quy Chau/0000-0002-6787-2757; Duszynska, Wieslawa/0000-0002-5880-4904; KAYA, ZEYNEP/0000-0002-8468-2103; Dragan, Barbara/0000-0003-3108-4211; Gupta, Umesh/0000-0001-7717-1404; Navarro Fuentes, Karla Reyna/0000-0002-6894-8872; zali, Mohammadreza/0000-0002-9027-4560; Morocho Tutillo, Diego Rolando/0000-0002-4974-7856; El Kholy, Amani/0000-0002-0645-7664; Kanj, Souha/0000-0001-6413-3396; Assiri, Abdullah/0000-0002-5605-2876; Unal, Necmettin/0000-0002-9440-7893; Jayatilleke, Kushlani/0000-0002-3931-6630; KARABAY, OGUZ/0000-0003-1514-1685 WOS: 000341307100001 PubMed: 25179325 We report the results of an International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2007-December 2012 in 503 intensive care units (ICUs) in Latin America, Asia, Africa, and Europe. During the 6-year study using the Centers for Disease Control and Prevention's (CDC) U.S. National Healthcare Safety Network (NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 605,310 patients hospitalized in the INICC's ICUs for an aggregate of 3,338,396 days. Although device utilization in the INICC's ICUs was similar to that reported from ICUs in the U.S. in the CDC's NHSN, rates of device-associated nosocomial infection were higher in the ICUs of the INICC hospitals: the pooled rate of central line-associated bloodstream infection in the INICC's ICUs, 4.9 per 1,000 central line days, is nearly 5-fold higher than the 0.9 per 1,000 central line days reported from comparable U. S. ICUs. The overall rate of ventilator-associated pneumonia was also higher (16.8 vs 1.1 per 1,000 ventilator days) as was the rate of catheter-associated urinary tract infection (5.5 vs 1.3 per 1,000 catheter days). Frequencies of resistance of Pseudomonas isolates to amikacin (42.8% vs 10%) and imipenem (42.4% vs 26.1%) and Klebsiella pneumoniae isolates to ceftazidime (71.2% vs 28.8%) and imipenem (19.6% vs 12.8%) were also higher in the INICC's ICUs compared with the ICUs of the CDC's NHSN. Copyright (C) 2014 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

Published
2014

17. Effect of cerebral embolization on regional autoregulation during cardiopulmonary bypass in dogs

Author

Hulya Sungurtekin, Thomas A. Orszulak, David J. Cook, and Umar S. Boston

Subjects
Pulmonary and Respiratory Medicine, Mean arterial pressure, medicine.medical_treatment, Hemodynamics, Blood Pressure, Cerebral autoregulation, law.invention, Dogs, law, Laser-Doppler Flowmetry, Cardiopulmonary bypass, Animals, Medicine, Embolization, Cerebral perfusion pressure, Cardiopulmonary Bypass, business.industry, Brain, Microspheres, Blood pressure, Cerebral blood flow, Regional Blood Flow, Cerebrovascular Circulation, Anesthesia, Surgery, Cardiology and Cardiovascular Medicine, business
Abstract

Background . Embolization during cardiopulmonary bypass probably alters cerebral autoregulation. Therefore, using laser Doppler flowmetry we investigated the cerebral blood flow velocity changes in response to changes in arterial pressure, before and after embolization in a canine bypass model. Methods . After Institutional Animal Care and Use Committee approval, 8 anesthetized dogs had a laser Doppler flow probe positioned over the temporoparietal dura. During 37° C cardiopulmonary bypass, the cerebral blood flow velocity response to changing mean arterial pressure (40 to 85 mm Hg in random order) was assessed before and after systemic embolization of 100 mg of 97-μm latex microspheres. Results . Before embolization, cerebral blood flow velocity increased 39% as mean arterial pressure increased from 40 to 85 mm Hg. Following embolization, a 94% increase in cerebral blood flow velocity was demonstrated over the same mean arterial pressure range. The slopes of the curves relating cerebral blood flow velocity to mean arterial pressure were 0.21 ± 0.74 and 1.31 ± 0.87, before and after embolization ( p = 0.016) respectively. Conclusions . Regional cerebral blood flow autoregulation may be impaired by microembolization known to occur during cardiopulmonary bypass, increasing the dependence of cerebral blood flow on mean arterial pressure.

Published
2000

18. Characteristics and outcomes of 974 COVID-19 patients in intensive care units in Turkey

Author

Hülya Sungurtekin, Cansu Ozgen, Ulku Arslan, Kemal Tolga Saracoglu, Volkan Yarar, Ahmet Sari, Ayse Turan Civraz, Ali Aydin Altunkan, Hilal Ayoglu, Nilgun Kavrut Ozturk, Nihal Bulut Yuksel, Birgul Yelken, Elif Bombaci, Gokhan Kilinc, Damla Akman, Pinar Demir, Ferruh Ayoglu, Fulya Ciyiltepe, Ahmet Caliskan, and Simay Karaduman

Subjects
Medicine
Abstract

BACKGROUND: In our previous report on Turkish COVID-19 patients requiring intensive care, the 24 patients in a single ICU were elderly and mortality was high. We extended our analysis to include patients admitted to ten ICUs. OBJECTIVES: Report the demographics, clinical features, imaging findings, comorbidities, and outcomes in COVID-19 patients. DESIGN: Retrospective. SETTING: Intensive care unit. PATIENTS AND METHODS: The study includes patients with clinical and radiological confirmed or laboratory-confirmed COVID-19 infection who were admitted to ten ICUs between 15 March and 30 June 2020. MAIN OUTCOME MEASURES: Clinical outcomes, therapies, and death during hospitalization SAMPLE SIZE: 974, including 571 males (58%). RESULTS: The median age (range) was 72 (21–101) years for patients who died (n=632, 64.9%) and 70 (16–99) years for patients who lived (n=342, 35.2%) (P

Published
2021
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19. Catheter entrapment during balloon angioplasty in patient with in-stent restenosis: an unusual complication and its surgical management

Author

Vefa Ozcan, Hulya Sungurtekin, Ibrahim Goksin, Ender Semiz, Ercan Gurses, Ahmet Baltalarli, and Mustafa Saçar

Subjects
Male, angiocardiography, right coronary artery, Percutaneous, medicine.medical_treatment, heparin, Balloon, Coronary Angiography, Restenosis, Angioplasty, Transluminal, Percutaneous Coronary, emergency surgery, Angioplasty, Balloon, Coronary, Coronary Artery Bypass, catheter complication, balloon catheter entrapment, adult, article, stenosis, Middle Aged, Catheter, medicine.anatomical_structure, operating room, Right coronary artery, Stents, Radiology, Cardiology and Cardiovascular Medicine, Artery, Pulmonary and Respiratory Medicine, Reoperation, medicine.medical_specialty, percutaneous transluminal angioplasty, Coronary Restenosis, angina pectoris, coronary artery bypass graft, medicine.artery, Angioplasty, medicine, case report, Humans, human, Angina, Unstable, guide wire, business.industry, Balloon catheter, medicine.disease, anamnesis, Surgery, business, in stent restenosis
Abstract

Entrapment of coronary angioplasty hardware is one of the rare complications of percutaneous coronary artery interventions. We reported herein a case of 58-year-old man with an entrapped balloon catheter and guidewire within the right coronary artery during the application of a conventional balloon angioplasty for in-stent restenosis. Surgical removal of the entrapped balloon catheter and guidewire was performed successfully with a coronary artery bypass grafting to the affected vessel. The application of the balloon angioplasty for in-stent restenosis requires every caution against such type of complications. © 2007 by Blackwell Futura Publishing, Inc.

Published
2007

20. Iatrogenic cardiac herniation and torsion after surgery for a penetrating cardiac injury

Author

Gokhan, Onem, Ahmet, Baltalarli, Hulya, Sungurtekin, Harun, Evrengul, Ali Vefa, Ozcan, Seyda, Kaya, and Mustafa, Sacar

Subjects
Male, Pacemaker, Artificial, Torsion Abnormality, Hernia, Adolescent, Heart Diseases, Iatrogenic Disease, Wounds, Penetrating, Wounds, Stab, Brief Communication, body regions, Heart Injuries, biological sciences, otorhinolaryngologic diseases, Humans, Herniorrhaphy
Abstract

Cardiac herniation and torsion is a rare condition associated with a high mortality rate. We present an unusual case of sudden cardiogenic shock that was caused by torsion and herniation of the heart after an operation for a penetrating cardiac injury. The patient was successfully treated by urgent surgical intervention.

Published
2007

22. Preservation of pleural integrity in patients undergoing coronary artery bypass grafting: effect on postoperative bleeding and respiratory function

Author

Ibrahim, Goksin, Ahmet, Baltalarli, Mustafa, Sacar, Hulya, Sungurtekin, Vefa, Ozcan, Ercan, Gurses, Seyda, Kaya, and Harun, Evrengul

Subjects
Lung Diseases, Male, Chi-Square Distribution, Incidence, Hemorrhage, Statistics, Nonparametric, Respiratory Function Tests, Pleural Effusion, Logistic Models, Postoperative Complications, Humans, Pleura, Female, Hospital Mortality, Prospective Studies, Coronary Artery Bypass, Internal Mammary-Coronary Artery Anastomosis
Abstract

The purpose of this study was to evaluate the influence of preserved integrity of pleura on postoperative bleeding and respiratory function in patients undergoing coronary artery bypass grafting (CABG).Seventy-two CABG patients who received pedunculated IMA graft without opening the pleura (group of intact pleura, group IP) between July 2002 and September 2004 were matched to 72 CABG patients who received pedunculated IMA graft with opened pleura (group of opened pleura, group OP). To match the patients with IP and unique patients with OP, logistic regression was used to develop a propensity score. The C statistic for this model was 0.79. Patients with IP were matched to unique patients with OP with an identical 5-digit propensity score. If this could not be done, we proceeded to a 4-, 3-, 2-, or 1-digit match. Patients characteristics were well matched. There were no differences in preoperative and peroperative variables between the groups. The incidence of postoperative pleural effusion and thoracentesis were significantly lower in group IP than group OP (pleural effusion in 15.2 versus 30.5%; p = 0.029, thoracentesis in 5.5 versus 18.5%; p = 0.036). Other pulmonary complications such as prolonged ventilation, reintubation, pneumothorax, atelectasis, diaphragmatic paralysis were similar in both groups. Patients with IP had significantly lower blood loss (520 versus 870 ml; p0.001) and whole blood unit transfusion (26.3 versus 41.6%, p = 0.036). Also, intensive care unit and hospital stay were similar in both groups.Meticulous internal mammary artery harvesting and preservation of the pleural integrity significantly reduces postoperative bleeding and pleural effusion.

Published
2006

23. Differential perfusion: a new technique for isolated brain cooling during cardiopulmonary bypass

Author

Hulya Sungurtekin, John A Macoviak, Umar S. Boston, David J. Cook, and Christopher G.A. McGregor

Subjects
Pulmonary and Respiratory Medicine, Aortic arch, medicine.medical_specialty, Swine, Aorta, Thoracic, law.invention, law, Hypothermia, Induced, Internal medicine, medicine.artery, Ascending aorta, Cardiopulmonary bypass, Medicine, Animals, Aorta, Cardiopulmonary Bypass, business.industry, Brain, Cannula, Perfusion, Blood pressure, Anesthesia, Descending aorta, cardiovascular system, Cardiology, Surgery, Cardiology and Cardiovascular Medicine, business
Abstract

Background . The purpose of this study was to determine the feasibility of differential perfusion of the aortic arch and descending aorta during cardiopulmonary bypass using a cannula designed for aortic segmentation. Methods . Pigs weighing 57 kg (n = 8), underwent cardiopulmonary bypass using the dual lumen aortic cannula. An inflatable balloon separated proximal (aortic arch) and distal (descending aorta) ports. During differential perfusion, the aorta was segmented and the arch and descending aorta perfused differentially using parallel heat exchangers. Ability to independently control brain and body temperature, cardiopulmonary bypass flow rate and mean arterial blood pressure was determined. Results . During differential perfusion cerebral hypothermia (27°C) with systemic normothermia (38°C) was established in 23 minutes. Independent control of arch and descending aortic flow and mean arterial blood pressure was possible. Analysis of internal jugular venous O 2 saturation data indicated an increase in the ratio of cerebral O 2 supply to demand during differential perfusion. Conclusions . A cannulation system segmenting the aorta allows independent control of cerebral and systemic perfusion. This device could provide significant cerebral protection while maintaining the advantages of warm systemic cardiopulmonary bypass temperatures.

Published
2000

24. Relationship between Cardiopulmonary Bypass Flow Rate and Cerebral Embolization in Dogs

Author

Hulya Sungurtekin, David J. Cook, and Walter Plöchl

Subjects
Mean arterial pressure, Pump flow, medicine.medical_treatment, animal experiment, Hemodynamics, Blood Pressure, brain embolism, Risk Assessment, animal tissue, arterial carbon dioxide tension, law.invention, brain tissue, Coronary circulation, Dogs, law, Coronary Circulation, Cardiopulmonary bypass, Animals, Medicine, brain blood flow, Embolization, Fluorescent Dyes, nonhuman, Cardiopulmonary Bypass, business.industry, Vascular disease, pathogenesis, article, Cerebral blood flow, medicine.disease, Microspheres, Cerebral emboli, blood flow velocity, Anesthesiology and Pain Medicine, Blood pressure, medicine.anatomical_structure, priority journal, Intracranial Embolism, Anesthesia, dog, hemoglobin determination, mean arterial pressure, business
Abstract

Background Cerebral embolization is a primary cause of cardiac surgical neurologic morbidity. During cardiopulmonary bypass (CPB), there are well-defined periods of embolic risk. In theory, cerebral embolization might be reduced by an increase in pump flow during these periods. The purpose of this study was to determine the CPB flow-embolization relation in a canine model. Methods Twenty mongrel dogs underwent CPB at 35 degrees C with alpha-stat management and a fentanyl-midazolam anesthetic. In each animal, CPB flow was adjusted to achieve a mean arterial pressure of 65-75 mmHg. During CPB, an embolic load of 1.2 x 10(5) 67 microm fluorescent microspheres was injected into the arterial inflow line. Before and after embolization, cerebral blood flow was determined using 15-microm microspheres. Tissue was taken from 12 brain regions and microspheres were recovered. The relation between pump flow and embolization/g of brain was determined. Results The mean arterial pressure at embolization was 67 +/-4 mmHg, and the range of pump flow was 0.9-3.5 l x min(-1)x m(-2). Cerebral blood flow was independent of pump flow. At lower pump flow, the percentage of that flow delivered to the brain increased. There was a strong inverse relation between pump flow and cerebral embolization (r = -0.708, P < 0.000 by Spearman rank order correlation). Conclusions Cerebral embolization is determined by the CPB flow. At an unchanged mean arterial pressure, as pump flow is reduced, a progressively greater proportion of that flow is delivered to the brain.

Published
1999

25. Tramadol Versus Low Dose Tramadol-paracetamol for Patient Controlled Analgesia During Spinal Vertebral Surgery

Author

Esad Emir, Simay Serin, Hakan Erbay, Hülya Sungurtekin, and Erkan Tomatir

Subjects
paracetamol, patient controlled analgesia, postoperative analgesia, spinal vertebral surgery, tramadol, Medicine (General), R5-920
Abstract

Pain intensity may be high in the postoperative period after spinal vertebral surgery. The aim of the study was to compare the effectiveness and cost of patient controlled analgesia (PCA) with tramadol versus low dose tramadol-paracetamol on postoperative pain. A total of 60 patients were randomly divided into two groups. One group received 1.5 mg/kg tramadol (Group T) while the other group received 0.75 mg/kg tramadol plus 1 g of paracetamol (Group P) intravenously via a PCA device immediately after surgery and the patients were transferred to a recovery room, Tramadol was continuously infused at a rate of 0.5 mL/h in both groups, at a dose of 10 mg/mL in Group T and 5 mg/mL in Group P. The bolus and infusion programs were adjusted to administer a 1 mL bolus dose of tramadol with a lock time of 10 minutes. In Group P, 1 g of paracetamol was injected intravenously every 6 hours. The four-point nausea scale, numeric rating scale for pain assessment, Ramsey sedation scale, blood pressure, heart rate, respiration rate, peripheral oxygen saturation values and side effects were recorded at 0, 15 and 30 minutes, and at 1, 2, 4, 6, 12, 18 and 24 hours. The time to reach an Aldrete score of 9 was also recorded. A cost analysis for both groups was performed. In Group P, the numeric rating scale scores were significantly lower than that in Group T at 0 and 15 minutes. The number of side effects, additional analgesic requirement and the total dose of tramadol were lower in Group P than in Group T. However, the total cost of postoperative analgesics was significantly higher in Group P than in Group T (p < 0.001). We conclude that PCA using tramadol-paracetamol could be used safely for postoperative pain relief after spinal vertebral surgery, although at a higher cost than with tramadol alone.

Published
2010
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26. [APACHE II, APACHE III, SOFA scoring systems, platelet counts and mortality in septic and nonseptic patients]

Author

Balci C, Sungurtekin H, Gürses E, and HULYA sungurtekin

Subjects
APACHE, Adult, Aged, Female, Humans, Intensive Care Units, Male, Middle Aged, Platelet Count, Predictive Value of Tests, Prospective Studies, Shock, Septic/*diagnosis/mortality/pathology, Turkey/epidemiology, bacterial infections and mycoses
Abstract

BACKGROUND: The aim of the current prospective study was to examine the prognostic value of APACHE II, APACHE III (Acute Physiology and Chronic Health Evakuation II and III) and SOFA (Sepsis-related Organ Failure Assessment) scores and platelet counts in septic and nonseptic patients hospitalized and treated in ICU units. METHODS: One hundred and twenty ICU patients were included in this study. Patients were grouped as septic survivors, septic nonsurvivors, nonseptic survivors and nonseptic nonsurvivors. The SOFA, APACHE II and III scores, and platelet counts were recorded at the admission in the ICU units and discharge.from the hospital. RESULTS: Patients were grouped as septic survivors (n=42), septic nonsurvivors (n=14), nonseptic survivors (n=48) and nonseptic nonsurvivors (n=16). The highest SOFA, APACHE II and III scores and the lowest platelet counts were observed in septic nonsurvivors when compared with the other patient groups. All score values and platelet counts were found to be significant in prediction of mortality in septic patients. CONCLUSIONS: According to our results obtained in septic and non-septic patients, we concluded that SOFA, APACHE II and III scores and platelet counts might be used in the prediction of mortality in septic patients.

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