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To present a comprehensive overview of different risk factors for early onset preeclampsia (<34 weeks gestation, EOP) vs. late onset (LOP). South-Reunion University's maternity (Reunion Island, Indian Ocean). 18.5 year-observational population-based cohort study (2001–2019). Epidemiological perinatal database with information on obstetrical and neonatal risk factors. All consecutive singleton pregnancies (>21 weeks) compared with all preeclamptic pregnancies delivered in the south of Reunion island. Comparing risk factors between EOP and LOP. Among 1814 singleton preeclamptic pregnancies (600 EOP and 1214 LOP), EOP women were older than LOP 29.5 vs. 28.6 years, p =.009, primigravidas (OR 0.78 [0.63–0.96], p =.02) were prone to LOP. History of preeclampsia (PE) (aOR 12.8 vs. 7.1), chronic hypertension (aOR 6.5 vs. 4.5) had much higher adjusted odds ratios for EOP than for LOP, p <.001. Specific to EOP: coagulopathies (aOR 2.95, p =.04), stimulated pregnancies (aOR 3.9, p =.02). Specific to LOP: renal diseases (aOR 2.0, p =.05) and protective effect for smoking (aOR 0.75, p =.008). EOP women were prone to have a lower BMI. "Placental preeclampsia" (defective placentation) being linked to early onset PE (<34 weeks gestation) while "maternal preeclampsia" (maternal cardiovascular predisposition) being typically manifesting as the late form of the disease LOP is not systematically verified. Future researches are needed to propose a more adapted paradigm. Risk factors for different preeclampsia phenotypes (early/late); challenging proposed models [ABSTRACT FROM AUTHOR]

The effect of chemically defined extracts from Echinacea angustifolia roots on rhinovirus infection is evaluated using three preparations produced by extractions from E. angustifolia roots. The extracts of Echinacea angustifolia root, either alone or in combination, do not have clinically significant effects on infection with a rhinovirus or on the clinical illness that results from it.

Objectives. We examined the pregnancy outcomes of three ethnic groups: African-American Blacks, non-Hispanic Whites, and Filipinos. In an attempt to reduce ethnic dissimilarities in parental employment and access to health care, this investigation compared the single-live-birth outcomes of married, adult women who resided in the state of Hawaii and who indicated that their spouse was no active-duty status in the US military. Methods. The date for this study were obtained from the 1979-1989 Hawaii vital-record file that provides linked live birth-infant death information. Multiple logistic regression was used to calculate odds ratios for the independent effects of maternal factors on low birthweight and neonatal mortality. Results. Significant differences in maternal age maternal education, paternal education, parity, hospital of delivery, and use of prenatal care were observed among the ethnic groups. The results of a logistic regression analysis of low birthweight indicated significantly higher risks for Filipinos and Blacks compared with Whites. For very low birthweight, only an increased risk for Blacks was observed. No ethnic differences in neonatal mortality were found. Conclusions. This investigation revealed more comparable infant mortality experiences among the ethnic groups in spite of persistent birthweight differences. (Am J Public Health. 1993;83:1721-1725), Infants born to Filipinos and blacks may have a greater risk of having low birth weight than infants born to whites. Researchers examined the birth records from 1979 to 1989 in three ethnic groups residing in Hawaii. These groups were African-American blacks, non-Hispanic whites and Filipinos. the mothers were married to active-duty military men and at least 18 years old. Parental and prenatal care, pregnancy outcome, birth weight and delivery date statistics varied significantly according to ethnic group. White infants had the lowest rate of low birth weight and early delivery. Black and Filipino infants had the highest risk for low birth weight. However, African-American infants had the highest risk for very low birth weight. The rates for Filipinos and whites were comparable. The risk of infant mortality was not influenced by ethnicity although a higher risk was identified for blacks.