129 results on '"Hui-Sheng Wang"'
Search Results
2. Case Report: Opportunities for Treatment of Severe COVID-19 Patients—Lessons From a Death Case
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Yan Wang, Zhuo Niu, Jia-Lin Peng, Hui-Sheng Wang, and Ke Zhang
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SARS-CoV-2 ,COVID-19 ,severe ,rescue ,treatment ,Medicine (General) ,R5-920 - Abstract
With the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the incidence of coronavirus disease (COVID-19) increases each day. To date, there is no specific anti-SARS-CoV-2 drug. The usual approach to treating COVID-19 is treating its symptoms. However, this approach is limited by the different conditions of each area. We treated a 57-year-old man who was initially diagnosed with a severe type of the infection, but he progressed to a critical condition and eventually died. We learned valuable lessons from this case. The first lesson is the need to use immediate invasive mechanical ventilation if there is no obvious improvement after using non-invasive ventilation for several hours, which directly affects the prognosis. Another lesson is the risk involved in transferring severe COVID-19 patients. In the process of transfer, various threats may be encountered at any time. Thus, accurate assessment of the patient's condition and strict medical conditions are highly required. During the patient's 25-day treatment, we performed cardiopulmonary resuscitation twice. Currently, many patients require invasive mechanical ventilation and transfer to a superior hospital. We hope our findings will provide some advice and help for treating severe and critical COVID-19 cases. more...
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- 2020
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Catalog
3. The three-body decays B(s)→ρf0(X)→ρπ−π+ in pQCD factorization approach
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Hui-sheng Wang, Xing-lin Wang, Fa-nong Zheng, Shao-min Liu, Jing Cao, and Qing-song Wang
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Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
In this paper, we study three-body decays B(s)→ρf0(X)→ρπ−π+ in the perturbative QCD (pQCD) factorization approach. By using two-pion distribution amplitudes (DAs), these decays can proceed mainly via quasi-two-body channels. The Flatté model for the f0(980) resonance and the Breit–Wigner formula for the f0(500), f0(1500), and f0(1790) resonances are adopted to parameterize the time-like scalar form factors. We also use Bugg's model for the wide f0(500) as a comparison. We evaluate S-wave resonance contributions, and show the contributions to the B(s)→ρπ+π− decay spectrums with respect to the two-pion invariant mass M(π+π−). The pQCD prediction of B→ρf0(500) is B(B0→ρ0f0(500))=4.43×10−8, B(B+→ρ+f0(500))=3.84×10−8 for Breit–Wigner model, and B(B0→ρ0f0(500))=4.91×10−8, B(B+→ρ+f0(500))=4.07×10−8 for Bugg's model. We also predict other resonance contributions B(Bs→ρ0f0(980))=8.91×10−8, B(Bs→ρ0f0(1500))=1.43×10−8 and B(Bs→ρ0f0(1790))=2.78×10−9. This study in pQCD approach can provide a ready reference to the running and forthcoming experiments. Further improvements in theories and experiments are expected so that we can understand the inner structure of the scalar mesons f0. more...
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- 2017
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4. Modulating the structural topologies from star-shape to cross-shape for Co–Dy heterometallic complexes with slow magnetic relaxation behavior
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Hui-Sheng Wang, Chun-Fang Yu, Si-Qi Ye, Yong Chen, Xueru Liu, Yanfang Wu, Pengfei Zhou, and Yi-Quan Zhang
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General Materials Science ,General Chemistry ,Condensed Matter Physics - Abstract
A star-like CoIII2DyIII2 complex (1) and a cross-shaped CoII/III–Dy complex (2) have been obtained, in which 1 exhibits double magnetic relaxation behavior, while 2 only shows slow magnetic relaxation signals. more...
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- 2023
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5. Geochemistry, geochronology and fluid inclusion studies of the Dongji epithermal gold deposit in Fujian province, south‐east China
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Liang‐Liang Huang, Hong‐Rui Fan, Feng‐Shan Ma, Ri‐Fu Liu, Hui‐Sheng Wang, Guang‐Shi Zheng, and Zhi‐Cheng Zhang
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Geology - Published
- 2022
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6. Significantly Enhancing the Single-Molecule-Magnet Performance of a Dinuclear Dy(III) Complex by Utilizing an Asymmetric Auxiliary Organic Ligand
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Hui-Sheng Wang, Peng-Fei Zhou, Jia Wang, Qiao-Qiao Long, Zhaobo Hu, Yong Chen, Jing Li, You Song, and Yi-Quan Zhang
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Inorganic Chemistry ,Physical and Theoretical Chemistry - Abstract
In this work, we employed an asymmetric auxiliary organic ligand (1,1,1-trifluoroacetylacetone, Htfac) to further regulate the magnetic relaxation behavior of series of Dy
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- 2021
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7. Regulating the distortion degree of the square antiprism coordination geometry in Dy–Na single ion magnets
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Hui-Sheng Wang, Ke Zhang, Zaichao Zhang, Zhao-Bo Hu, Zhi-Quan Pan, You Song, and Jia Wang
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Schiff base ,Denticity ,Materials science ,Ligand ,General Chemistry ,Condensed Matter Physics ,Magnetic susceptibility ,Ion ,Square antiprism ,chemistry.chemical_compound ,Crystallography ,chemistry ,Molecule ,General Materials Science ,Coordination geometry - Abstract
A novel [DyIIINaI] complex, [DyNa(L)2(MeOH)]·MeOH (1, H2L = N,N′-bis(2-oxy-3-methoxybenzylidene)-1,2-phenylenediamine), and a zigzag 1D chain based on the [DyIIINaI2] subunit, [DyNa2(L)2(NO3)]n·MeOH (2), were obtained by employing a multidentate Schiff base ligand H2L reacting with Dy(NO3)3·5H2O, NaN3 and NMe4OH·5H2O in MeOH or reacting with Dy(NO3)3·5H2O and NaOH in methanol. Structural analyses revealed that the DyIII in 1 and 2 is sandwiched between two L2− ligands, namely, the DyIII ion was coordinated by four phenoxido O and four amine N atoms from two L2− ligands. SHAPE software calculations and structural analysis indicated that the coordination geometry of DyIII in 1 and 2 is a distorted square antiprism (D4d), but the distortion degree of DyIII in 1 was smaller than that in 2. Additionally, in 1, one NaI is located on one of the N2O2 planes, and the NaI is coordinated by three phenoxido O and three methoxy O atoms from two L2− ligands and one coordinated MeOH molecule. However, in 2, two NaI ions are located on each of the N2O2 planes, in which the coordination environment of each NaI is completed by three phenoxido O atoms, three methoxy O atoms and two O atoms from one NO3− ion. Moreover, the [DyIIINaI2] units are linked into a zigzag 1D chain by nitrate anions. ac magnetic susceptibility measurements revealed that both complexes 1 and 2 exhibit field-induced single ion magnet behavior under a 1000 Oe dc field, with values of the effective energy barrier (Ueff) of 65.33(1) K for 1 and 84.23(1) K for 2. Interestingly, the Ueff values of 1 and 2 are both higher than the corresponding value of 40.1 K for a reported complex with the coordination geometry of a bicapped triangular prism. The moderate SIM performance of 1 and 2 in the Dy(III)-based SIMs with a SAP coordination geometry could be ascribed to the compressed SAP coordination environment of DyIII ions, dipole–dipole interactions and the deviation of the anisotropic axes from the S8 axis. more...
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- 2021
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8. Spinal 5-HT
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Xiao-Cui, Yuan, Yu-Ying, Wang, Li-Xia, Tian, Xiang-Ji, Yan, Yi-Xiao, Guo, Yu-Long, Zhao, Sani S, Baba, Hong, Jia, Hui-Sheng, Wang, Man, Li, and Fu-Quan, Huo
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Rats, Sprague-Dawley ,Mice ,Serotonin ,Electroacupuncture ,Spinal Cord ,Symporters ,Animals ,Receptor, Serotonin, 5-HT2A ,Chronic Pain ,Osteoarthritis, Knee ,Receptors, GABA-A ,Rats - Abstract
Knee osteoarthritis (KOA) is a highly prevalent, chronic joint disorder, and it is a typical disease which can develop chronic pain. Our previous study has proved that endocannabinoid (2-AG)-CB1R-GABA-5-HT pathway is involved in electroacupuncture (EA) mediated inhibition of chronic pain. However, it is still unclear which among the 5-HT receptor subtype is involved in EA evoked 5-HT mediated inhibition of chronic pain in the dorsal spinal cord. 5-HT more...
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- 2022
9. Activation and blockade of 5-HT
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Jia-Wei, Wang, Jian, Liu, Zhao-Long, Wang, Feng, Gao, Jie, Yang, Xiao-Chen, Wang, Yuan, Guo, Yong, Wang, Bo-Rui, Ma, Hui-Sheng, Wang, Yi-Wei, Hu, Yu-Ming, Zhang, Yan-Ping, Hui, and Li, Zhang
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Rats, Sprague-Dawley ,Serotonin ,Parkinsonian Disorders ,Animals ,Parkinson Disease ,Oxidopamine ,Hippocampus ,Rats - Abstract
Cognitive dysfunction is a common symptom in Parkinson's disease (PD). Serotonin4 (5-HT
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- 2021
10. Application of dynamic display technology to identify gaps after pulmonary vein isolation in catheter ablation of atrial fibrillation
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Wei-Tso Chen, Li-Wei Lo, Wen-Chin Tsai, Yenn-Jiang Lin, Shih-Lin Chang, Yu-Feng Hu, Fa-Po Chung, Jo-Nan Liao, Ta-Chuan Tuan, Tze-Fan Chao, Chin-Yu Lin, Ting-Yung Chang, Ling Kuo, Chih-Min Liu, Shin-Huei Liu, Wen-Han Cheng, Linda Lin, An Nu-Khanh Ton, Chu-Yu Hsu, Chhay Chheng, Ahmed Elimam, Hui-Sheng Wang, Ming-Ren Kuo, Pei-Heng Kao, and Shih-Ann Chen more...
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Technology ,Treatment Outcome ,Pulmonary Veins ,Atrial Fibrillation ,Catheter Ablation ,Humans ,Cardiology and Cardiovascular Medicine - Abstract
The identification of post pulmonary vein isolation (PVI) gaps by activation and voltage maps is time-consuming. This study aimed to investigate the characteristics, efficiency and accuracy of LiveView dynamic display module (EnSite™ Dynamic Display; Abbott, Abbott Park, IL, USA) in unmasking post PVI gaps and conduction block line.Twenty four patients with paroxysmal atrial fibrillation (PAF) who failed to achieve first-pass PVI or with recurrent PAF were enrolled. Ninety-six pulmonary veins (PVs) were evaluated, and gaps were identified in 25 (26.0%) PVs. The gap location was confirmed by activation and propagation maps; 110 frames on gaps and 118 frames on block lines were analyzed by using LiveView module. We defined isochronal crowding in the local activation time (LAT) mode as three colors between two adjacent electrodes. Each frame was classified as with or without isochronal crowding in LAT mode and one/continuous color or isochronal discontinuity in reentrant mode. The gray color inside the PVs was considered to represent conduction block.The isochronal crowding could be found on both gap and block line in LAT mode, whereas isochronal discontinuity only presented on the block line in reentrant mode. The sensitivity and specificity of isochronal discontinuity or gray color in reentrant mode to identify block line were 61.0% and 100%, respectively. The sensitivity and specificity of isochronal crowding or gray color in LAT mode to identify block line were 71.2% and 71.8%, respectively.Reentrant mode in LiveView module is very specific in identifying block lines. We proposed an efficient, practical algorithm to differentiate the block line from PV gaps. more...
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- 2021
11. Clinical course of patients with severe SARS-CoV-2 infection co-treatment with Jin Si Herbal Tea in Eastern Taiwan: A retrospective cohort study
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Pei-Chen Li, Hui-Sheng Wang, Marthandam Asokan Shibu, Jhen Wang, Shiau-Huei Huang, Jeng-Hung Wang, Ji-Hung Wang, Chih-Yang Huang, Chien-Yi Chiang, Yu-Jung Lin, Tsung-Jung Ho, Shinn-Zong Lin, Hui-Chun Chung, Hsin-Yuan Yu, San-Hua Su, Ying-Fang Chou, Chia-Hui Tai, Dah-Ching Ding, and Cheng Yen Shih more...
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Complementary and alternative medicine - Abstract
Coronavirus disease-2019 (COVID-19) has affected more than 608 million people and has killed 6.5 million people in the world. A few studies showed traditional Chinese medicine can be beneficial for COVID-19 treatment. An herbal preparation Jin Si Herbal Tea (JS) was formulated with herbal extracts known for their potential to decrease spike protein and ACE2 interaction, 3CL, and TRPMSS2 protease activity, and thus aimed to evaluate the clinical course of JS co-treatment along with the usual treatment schedule given for severe COVID-19 patients.This retrospective cohort study included patients with severe COVID-19 admitted to Hualien Tzu Chi Hospital between June and July 2021. All the patients were co-treated with JS and the primary outcome was death. The secondary outcomes included laboratory exam, Ct value, clinical course, and hospital stays. There were 10 patients recruited in this study and divided into 70 years and ≧ 70 years groups (n = 5 in each group).Older patients (≧70 years) had a higher Charlson Comorbidity Index, VACO index, and lower hemoglobin levels than 70 years patients. The trend of lymphocyte count, LDH, D-dimer, and Ct value of non-survivors was not consistent with previous studies. The death rate was 20% and the recovery rate to mild illness in 14 days was 40%.In conclusion, this is the first clinical study of JS co-treatment in severe COVID-19 patients. JS co-treatment might reduce death rate and recovery time. Further large-scale clinical trials would be expected. more...
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- 2021
12. Modulating the structural topologies and magnetic relaxation behaviour of the Mn–Dy compounds by using different auxiliary organic ligands
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You Song, Zaichao Zhang, Zhao-Bo Hu, Hui-Sheng Wang, Zhi-Quan Pan, Ke Zhang, and Yong Chen
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chemistry.chemical_classification ,Ketone ,Ligand ,Metal ions in aqueous solution ,General Chemistry ,Catalysis ,Ion ,Magnetization ,Crystallography ,chemistry ,Zigzag ,Materials Chemistry ,Tetrahedron ,Molecule - Abstract
A pentanuclear heterometallic complex [MnIII4DyIII(HL)4{(py)2CO2}2Cl2](OH) (1, H3L = 2-((2-hydroxybenzylidene)amino)propane-1,3-diol, (py)2C(OH)2 = the gem-diol form of 2,2′-dipyridyl ketone) and a one-dimensional (1D) chain [Mn2Dy(HL)2(hmp)2(CH3COO)2N3]n·H2O (2, Hhmp = 2-pyridinemethanol) were obtained by the assemblies of the H3L ligand and Dy(NO3)3·5H2O with MnCl2·4H2O and 2,2′-dipyridyl ketone or with manganese acetate and 2-pyridinemethanol under different alkaline solutions. In 1, four MnIII ions formed an irregular tetrahedron, in which four MnIII ions were linked with the central DyIII by eight O atoms from HL2− or from (py)2CO22− ligands. In 2, one DyIII and two MnIII formed a [Mn2Dy] unit, in which the metal ions were bridged by one N3− ion and by four O atoms of two HL2− and two hmp− ligands, and then these [Mn2Dy] units were further linked by the O atoms from HL2− ligands and formed a 1D zigzag chain. Magnetic studies indicated that both complexes exhibit slow relaxation behavior, with the effective energy barriers of 7.9 K and 9.6(0) K for 1 and 2, respectively, which might represent new members for the rarely polynuclear Mn–Dy single molecule magnets. The orientations of the easy magnetization axes of DyIII ions in 1 and 2 were estimated by the Magellan program, indicating that the easy axes of DyIII in 1 are nearly directed to C16 and C47 from (py)2CO22− ligands, while the axis in 2 is almost directed to O5 (from the acetate ligand). more...
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- 2020
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13. Two Trinuclear CuIIComplexes: Effect of Phosphonate Ligand on the Magnetic Property and Electrocatalytic Reactivity for Water Oxidation
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Ya-Rong Liu, Xia Zhang, Yuhua Fan, Mei Wang, Xue-Yang Mao, Ning-Ning Shi, Hui-Sheng Wang, and Jinmiao Wang
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010405 organic chemistry ,Ligand ,Metal ions in aqueous solution ,Organic Chemistry ,chemistry.chemical_element ,General Chemistry ,Crystal structure ,010402 general chemistry ,Electrochemistry ,01 natural sciences ,Biochemistry ,Phosphonate ,Magnetic susceptibility ,Copper ,0104 chemical sciences ,law.invention ,chemistry.chemical_compound ,Crystallography ,chemistry ,law ,Electron paramagnetic resonance - Abstract
Two trinuclear copper phosphonate complexes, [Cu3 (pda)3 (tBuPO3 )]⋅2(Et3 NH) (1) and [Cu3 (pda)3 (PhPO3 )]⋅2(Et3 NH) (2), have been synthesized and investigated by a combination of X-ray crystallography, PXRD, magneto- and electrochemistry, EPR, in situ UV-vis spectroelectrochemistry and DLS. The two complexes feature almost identical crystal structures, the anions of which are both supported by pda2- and tBuPO3 2- /PhPO3 2- groups, bridging three five-coordinated CuII atoms to form a crown-like structure. This is the first time that trinuclear copper phosphonate complexes have been isolated and characterized. Magnetic susceptibility measurements reveal that complexes 1 and 2 both display overall ferromagnetic characters, but with different exchange interactions between the metal ions within the two clusters. The electrocatalytic activity for water oxidation of the two complexes was preliminarily investigated, which reveals that both of the two complexes can carry out electrocatalytic water oxidation in a neutral system owing to the introduction of phosphonate ligands into the complexes, with a TOF of about 0.82 s-1 (1) and 0.58 s-1 (2), respectively. We propose that the presence of phosphonate ligands may affect the magnetic property and catalytic activity of the complexes. more...
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- 2019
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14. A Dy-based complex with the magnetic relaxation behavior regulated by enclosing one DyIII ion into a Calix[8]arene ligand
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Zhao-Bo Hu, Yong Chen, Cheng-Ling Yin, Hui-Sheng Wang, Zaichao Zhang, Zhi-Quan Pan, and Qiao-Qiao Long
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Materials science ,Ligand ,Metal ions in aqueous solution ,Infrared spectroscopy ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,Ion ,Inorganic Chemistry ,Dodecahedron ,Crystallography ,Materials Chemistry ,Molecule ,Physical and Theoretical Chemistry ,0210 nano-technology ,Anisotropy ,Powder diffraction - Abstract
A new Dy Na complex [DyIIINaI(CH3CO2)2(DMF)3(H6C8A)]·4DMF (1, DMF = N,N-dimethylformamide, H8C8A = p-tert-butylcalix[8]arene) was obtained and it was characterized by elemental analyses, IR spectroscopy, single-crystal X-ray diffraction analyses, PXRD and magnetic properties. In 1, one DyIII and one NaIII were linked by two O atoms from two CH3CO2− and the two metal ions were enclosed into a H8C8A. The remaining coordination sites of the DyIII and NaI ions were occupied by three O atoms from three DMF coordinated molecules. The DyIII ion in 1 adopts eight coordinate with a triangular dodecahedron. Magnetic property studies indicated complex 1 show slow magnetic relaxation behavior under 1000 Oe applied dc field. Additionally, the orientation of the anisotropy axis for the DyIII in 1 was estimated by Magellan program and the anisotropic axis is aligned along Dy1-O2 bond with an angle of 12.608°. more...
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- 2019
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15. Activation and blockade of dorsal hippocampal Serotonin6 receptors regulate anxiety-like behaviors in a unilateral 6-hydroxydopamine rat model of Parkinson’s disease
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Yi Wei Liu, Yu-Ming Zhang, Li Chen, Yuan Guo, Hui Sheng Wang, Kun Cheng Liu, Jin Zhang, Li Zhang, Shu Xuan Lv, and Wen Xie
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0301 basic medicine ,Agonist ,medicine.medical_specialty ,Elevated plus maze ,medicine.drug_class ,Chemistry ,General Medicine ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Endocrinology ,medicine.anatomical_structure ,Neurology ,Anxiogenic ,Dopamine ,Internal medicine ,medicine ,Neurology (clinical) ,Serotonin ,Medial forebrain bundle ,030217 neurology & neurosurgery ,5-HT receptor ,medicine.drug ,Basolateral amygdala - Abstract
Objectives: This study aimed to investigate the effect of serotonin6 (5-HT6) receptors in the dorsal hippocampus (dHip) on the regulation of Parkinson's disease (PD)-associated anxiety. Methods: We examined whether intra-dHip injection of both 5-HT6 receptor agonist and antagonist was involved in the regulation of anxiety-like behaviors in sham-operated rats and rats with unilateral 6-hydroxydopamine (6-OHDA) lesions of the medial forebrain bundle by the open-field and elevated plus maze (EPM) tests. Four weeks after injection of 6-OHDA, the concentrations of dopamine (DA), noradrenaline (NA) and 5-hydroxytryptamine (5-HT) in relative related brain regions were measured by reverse-phase high-performance liquid chromatography. Results: In sham-operated rats, intra-dHip injection of both 5-HT6 receptor agonist WAY208466 (3 and 6 µg/rat) and antagonist SB258585 (4 µg/rat) increased the percentage of time spent in the center area in the open-field test and percentages of open arm entries and open arm time in EPM test, indicating that induced anxiolytic effects. In the lesioned rats, WAY208466 (1.5, 3 and 6 µg/rat) produced anxiolytic responses, whereas SB258585 (2 and 4 µg/rat) produced anxiogenic effects. Neurochemical results showed that intra-dHip injection of WAY208466 (6 µg/rat) decreased NA level in the amygdala, and SB258585 (4 µg/rat) increased DA levels in the dHip and vHip in sham-operated rats, whereas WAY208466 increased DA levels in the dHip, vHip, and amygdala in the lesioned rats. Discussion: dHip 5-HT6 receptors are involved in the regulation of anxiety-like behaviors, which may be mediated through different neurochemical mechanisms, and the dHip is an important site involved in these effects. Abbreviation: PD: Parkinson's disease;6-OHDA: 6-hydroxydopamine; dHip: dorsal hippocampus; vHip: ventral hippocampus; 5-HT: serotonin; MFB: medial forebrain bundle; DA: dopamine; NA: noradrenaline; EPM: elevated plus-maze; GABA: gamma-aminobutyric acid; BLA: basolateral amygdala. more...
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- 2019
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16. Activation and blockade of 5-HT4 receptors in the dorsal hippocampus enhance working and hippocampus-dependent memories in the unilateral 6-hydroxydopamine lesioned rats
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Jia-Wei Wang, Jian Liu, Zhao-Long Wang, Feng Gao, Jie Yang, Xiao-Chen Wang, Yuan Guo, Yong Wang, Bo-Rui Ma, Hui-Sheng Wang, Yi-Wei Hu, Yu-Ming Zhang, Yan-Ping Hui, and Li Zhang
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Behavioral Neuroscience - Published
- 2022
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17. Influence of the Different Types of Auxiliary Noncarboxylate Organic Ligands on the Topologies and Magnetic Relaxation Behavior of Zn-Dy Heterometallic Single Molecule Magnets
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Zhao-Bo Hu, Hui-Sheng Wang, Jia Wang, You Song, Zaichao Zhang, Yi-Quan Zhang, and Ke Zhang
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010405 organic chemistry ,Ligand ,Dimer ,Crystal structure ,010402 general chemistry ,01 natural sciences ,0104 chemical sciences ,Inorganic Chemistry ,Magnetization ,Dodecahedron ,chemistry.chemical_compound ,Crystallography ,chemistry ,Ab initio quantum chemistry methods ,Molecule ,Physical and Theoretical Chemistry ,Coordination geometry - Abstract
In this work, we first synthesized a Zn-Dy complex, [Zn6Dy2(L)6(tea)2(CH3OH)2]·6CH3OH·8H2O (H2L = N-3-methoxysalicylidene-2-amino-3-hydroxypyridine, teaH3 = triethanolamine, 1), by employing H2L, anhydrous ZnCl2, and Dy(NO3)3·5H2O reacting with auxiliary ligand teaH3 in the mixture of CH3OH and DMF. When teaH3 and the solvent CH3OH in the reaction system of 1 were replaced by the auxiliary ligand 2,6-pyridinedimethanol (pdmH2) and the solvent MeCN, another Zn-Dy complex, [Zn4Dy4(L)6(pdm)2(pdmH)4]·10CH3CN·5H2O (2), was obtained. For 1, its crystal structure can be viewed as a dimer of two Zn3DyIII units. However, for 2, four DyIII form a zigzag arrangement, and each of its terminals linked two ZnII ions. Interestingly, although the structural topologies of 1 and 2 are different, the coordination geometries of DyIII in 1 and 2 are all triangular dodecahedron (TDD-8). The difference is that the continuous shape measure (CShM) values of DyIII in 1 are larger than the corresponding values in 2. Magnetic investigation revealed that the diluted sample 1@Y exhibits two magnetic relaxation processes, while 2 only exhibits a single relaxation process. Ab initio calculations indicated that, in the crystal lattice of 1, two complexes exhibiting slightly different CShM values of DyIII result in the double relaxation behavior of 1@Y. However, for 2, one of two DyIII fragments possesses a fast quantum tunneling of magnetization (QTM), resulting in its magnetic process presented at T < 1.8 K, so 2 exhibits single relaxation behavior. More importantly, the theoretical calculations also clearly indicated that the weak ligation at equatorial sites of DyIII in 1 and 2 ensure 1@Y and 2 possess SMM behavior, although the coordination geometry of DyIII (TDD-8) in 1 and 2 severely deviates from the ideal polyhedron and its axial symmetry is low. more...
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- 2021
18. Activation and Blockade of 5-HT 4 Receptors in the Dorsal Hippocampus Enhance Working and Hippocampus-Dependent Memories in the Unilateral 6-Hydroxydopamine Lesioned Rats
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Jia-Wei Wang, Jian Liu, Zhao-Long Wang, Feng Gao, Jie Yang, Xiao-Chen Wang, Yuan Guo, Yong Wang, Bo-Rui Ma, Hui-Sheng Wang, Yi-Wei Hu, Yu-Ming Zhang, Yan-Ping Hui, and Li Zhang
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History ,Polymers and Plastics ,Business and International Management ,Industrial and Manufacturing Engineering - Published
- 2021
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19. Regulation of magnetic relaxation behavior by replacing 3d transition metal ions in [M2Dy2] complexes containing two different organic chelating ligands
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You Song, Hui-Sheng Wang, Zhao-Bo Hu, Yong Chen, Cheng-Ling Yin, Yi-Quan Zhang, Zaichao Zhang, and Zhi-Quan Pan
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Materials science ,Magnetic moment ,010405 organic chemistry ,010402 general chemistry ,01 natural sciences ,0104 chemical sciences ,Ion ,Inorganic Chemistry ,Dodecahedron ,chemistry.chemical_compound ,Crystallography ,chemistry ,Ab initio quantum chemistry methods ,Diethylenetriamine ,Single-molecule magnet ,Ground state ,Quantum tunnelling - Abstract
Four tetranuclear 3d–4f complexes, namely [Fe2Ln2(L)2(teaH)2(Cl)2](NO3)2·4CH3CN (H2L = N1,N3-bis(3-methoxysalicylidene)diethylenetriamine, teaH3 = triethanolamine, Ln = Dy for 1 and Ln = Gd for 1′) and [Co2Ln2(L)2(pdm)2(CH3COO)2(CH3OH)2](NO3)2·xCH3OH·yH2O (pdmH2 = 2,6-pyridinedimethanol, Ln = Dy, x = 5 and y = 2.5 for 2 and Ln = Gd, x = 6 and y = 1.5 for 2′), have been reported. Two FeIII and two DyIII in 1 formed a zigzag Fe1–Dy1–Dy1a–Fe1a arrangement with a Fe1–Dy1–Dy1a angle of 105.328(3)°. However, in contrast to 1, two CoIII and two DyIII ions in 2 formed a more linear Co1–Dy1–Dy1a–Co1a arrangement with a Co1–Dy1–Dy1a angle of 141.86(2)°. Additionally, two DyIII ions in 1 are eight-coordinated with a triangular dodecahedron geometry, while two DyIII ions in 2 adopt nine-coordination with a muffin geometry. Magnetic studies revealed slow magnetic relaxation behavior for 1, with an energy barrier Ea of 6.9 K. For 2, single molecule magnet behavior was presented under a zero dc field with an effective energy barrier Ueff of 64.0(9) K. Ab initio calculations for 1 and 2 indicate that compared to 2, complex 1 has a larger transversal magnetic moment of its ground Kramers doublets (KD) and a larger value of the tunnelling parameter (Δt) for the exchanged coupled ground state, which may result in poor single molecule magnet behavior for 1. more...
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- 2019
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20. Synthesis, crystal structures and magnetic properties of a series of chair-like heterometallic [Fe4Ln2] (Ln = GdIII, DyIII, HoIII, and ErIII) complexes with mixed organic ligands
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Yi-Quan Zhang, Hui-Sheng Wang, Qiao-Qiao Long, Zhao-Bo Hu, Feng-Jun Yang, Zhi-Quan Pan, Cheng-Ling Yin, Lin Yue, and You Song
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chemistry.chemical_classification ,Ketone ,Materials science ,010405 organic chemistry ,Ligand ,Crystal structure ,010402 general chemistry ,01 natural sciences ,Magnetic susceptibility ,0104 chemical sciences ,Inorganic Chemistry ,Magnetic anisotropy ,Crystallography ,chemistry ,Ab initio quantum chemistry methods ,Molecule ,Single-molecule magnet - Abstract
Four chair-like hexanuclear Fe-Ln complexes containing mixed organic ligands, namely, [Fe4Ln2{(py)2CO2}4(pdm)2(NO3)2(H2O)2Cl4]·xCH3CN·yH2O (Ln = GdIII (1, x = 1, y = 0), DyIII (2, x = 1, y = 1), HoIII (3, x = 0, y = 2), and ErIII (4, x = 1, y = 3); (py)2CO2H2 = the gem-diol form of di-2-pyridyl ketone and pdmH2 = 2,6-pyridinedimethanol) have been obtained by employing di-2-pyridyl ketone and 2,6-pyridinedimethanol reacting with FeCl3 and Ln(NO3)3 in MeCN. The structures of 1-4 are similar to each other except for the number of lattice solvent molecules. Four FeIII and two LnIII in these complexes comprise a chair-like core with the "body" constructed by four FeIII ions and the "end" constructed by two LnIII ions. Among the four compounds, 2 shows field-induced single molecule magnet behavior as revealed by ac magnetic susceptibility studies, with the effective energy barrier and the pre-exponential factor of 22.07 K and 8.44 × 10-7 s, respectively. Ab initio calculations indicated that, among 2_Dy, 3_Ho and 4_Er fragments, the energy gap between the lowest two spin-orbit states for 2_Dy is the largest, while the tunneling gap for 2 is the smallest. These might be the reasons for complex 2 exhibiting SMM behavior. Additionally, the orientations of the magnetic anisotropy of DyIII in 2 were obtained by electrostatic calculations and ab initio calculations, both indicating that the directions of the main magnetic axis of Dy1 ions are almost aligned along Dy1-O5 (O5 from the pdm2- ligand). more...
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- 2019
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21. Single molecule magnet behaviors of Zn4Ln2 (Ln = DyIII, TbIII) complexes with multidentate organic ligands formed by absorption of CO2 in air through in situ reactions
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Yi-Quan Zhang, Qiao-Qiao Long, Cheng-Ling Yin, Zhi-Quan Pan, Zhao-Bo Hu, Jing Li, Hui-Sheng Wang, Zaichao Zhang, and You Song
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Materials science ,Denticity ,010405 organic chemistry ,Ligand ,Crystal structure ,010402 general chemistry ,01 natural sciences ,0104 chemical sciences ,Ion ,Inorganic Chemistry ,Crystallography ,Magnetization ,chemistry.chemical_compound ,chemistry ,Ab initio quantum chemistry methods ,Diethylenetriamine ,Single-molecule magnet - Abstract
In this work, we report the syntheses, crystal structures and magnetic properties of three novel Zn–Ln mixed metal complexes, namely [Zn4Dy2(L1)2(L2)2(N3)2]Cl2·2H2O (1), [Zn4Tb2(L1)2(L2)2(Cl)2][ZnN3Cl3]·2H2O (2), and [Zn4Gd2(L1)2(L2)2(Cl)2][ZnN3Cl3]·2H2O (3), in which L12− and L23− were formed from the ligand L [L = N1,N3-bis(3-methoxysalicylidene)diethylenetriamine] through in situ reactions. Interestingly, carbon dioxide in air was absorbed in the process of forming carbamate ligand L23−; this can be ascribed to the insertion of CO2 into M–N amide bonds. Moreover, 1 and 2 represent the first series of 3d–4f SMMs containing carbamate ligands by fixation of CO2 in air. Single-crystal X-ray diffraction analyses reveal that the crystal structures of 1 and 2 are anion-dependent, i.e., the apical positions of the two ZnII ions in 1 and 2 are occupied by an N atom of N3− and by Cl−, respectively. However, the topologies of 2 and 3 are similar. Two ZnII ions and one LnIII (Ln = Dy (1), Tb (2) and Gd (3)) form nearly linear trinuclear [Zn2Ln] units which are double-bridged by two L23− ligands. Magnetic studies reveal that two complexes show single molecule magnet behavior under a direct current (dc) field, with effective energy barriers (Ueff) of 30.66(5) K for 1 and 8.87(3) K for 2. Ab initio calculations reveal that the DyIII ions in 1 and the TbIII ions in 2 are axial in nature; however, a difference in the tunnel splitting of 1 and 2 leads to variation in the magnetization blockades of the two complexes. Theoretical calculations also indicate that the directions of the main magnetic axes severely deviate from the coordination atoms of the first spheres of DyIII and TbIII in 1 and 2; thus further results in poor SMM behavior of the two complexes. more...
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- 2019
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22. Modulation of the directions of the anisotropic axes of DyIII ions through utilizing two kinds of organic ligands or replacing DyIII ions by FeIII ions
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Hui-Sheng Wang, Zhao-Bo Hu, Cheng-Ling Yin, Zaichao Zhang, Yong Chen, and Zhi-Quan Pan
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chemistry.chemical_classification ,Ketone ,Materials science ,Ligand ,General Chemistry ,Condensed Matter Physics ,Ion ,Magnetization ,Crystallography ,Magnetic anisotropy ,chemistry ,Atom ,Tetrahedron ,Molecular symmetry ,General Materials Science - Abstract
To modulate the molecular symmetry of tetrahedral Dy4 complexes, in this paper, we reported two complexes based on a Dy4 or Dy2Fe2 tetrahedral unit, namely, [Dy4(NO3)(HL)4{(py)2C(OH)O}2](OH)·6CH3CN·0.5H2O (1, H3L = 2-((2-hydroxybenzylidene)amino) propane-1,3-diol, (py)2C(OH)2 = the gem-diol form of di-2-pyridyl ketone) and [Fe4Dy2(μ4-O)(HL)3{(py)2CO2}{(py)2C(OH)O}{(py)2C(OCH3)O}(L′)Cl3]Cl·6CH3CN·3.5H2O (2, H2L′ = 2-amino-1,3-propanediol). In 1, each of the four sides of the Dy4 tetrahedron was constructed from one O atom of one (py)2C(OH)O− ligand and one O atom of one HL12− ligand, one side was constructed from two O atoms of two (py)2C(OH)O− ligands, and the remaining side was not constructed from organic ligands. Consequently, NO3− in 1 adopts an unprecedented η4, η1, η1, μ4 coordination mode, in which one O atom (O17) linked with four DyIII and each of another two O atoms further coordinated with a DyIII ion. For 2, the tetrahedral unit was composed of two DyIII ions and two FeIII ions, and each of the two DyIII ions is further linked with an FeIII ion. Slow relaxation behavior was observed for both complexes, with an energy barrier of 8.73 K for 1 under a zero dc field and 13.80 K for 2 under a 1500 Oe dc field, respectively. The orientations of the magnetic anisotropy of DyIII in 1 and 2 were calculated by the Magellan program, indicating that the easy magnetization axes of the four DyIII ions in 1 were not directed to O17, while the axes in 2 are nearly parallel to each other. more...
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- 2019
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23. Synthesis, crystal structures and magnetic properties of a series of pentanuclear heterometallic [CuII3LnIII2] (Ln = Ho, Dy, and Gd) complexes containing mixed organic ligands
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Zhao-Bo Hu, Zhi-Yong Huang, Zaichao Zhang, Hui-Sheng Wang, Qiao-Qiao Long, Feng-Jun Yang, Wei Chen, Yong Chen, and You Song
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02 engineering and technology ,General Chemistry ,Crystal structure ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Magnetic susceptibility ,Catalysis ,0104 chemical sciences ,Crystallography ,Paramagnetism ,Magnetization ,Magnetic anisotropy ,chemistry.chemical_compound ,Ferromagnetism ,chemistry ,Diethylenetriamine ,Materials Chemistry ,Antiferromagnetism ,0210 nano-technology - Abstract
In this paper, we present the synthesis, crystal structures and magnetic properties of three complexes with formulae [Cu3Ln2(L)2(teaH)2(N3)2Cl2]·xCH3CN (H2L = N1,N3-bis(3-methoxysalicylidene)diethylenetriamine, teaH3 = triethanolamine; Ln = Ho, x = 3 for 1, Ln = Dy, x = 2 for 2 and Ln = Gd, x = 3 for 3), and the structural topologies of 1–3 are unprecedented. The structural analyses revealed that the metal ions in 1–3 formed a kite-like topology with Ln1, Ln2 and Cu1 located on the body, while Cu2 and Cu3 located on both wings. The dc data of 3 were fitted, which showed that the magnetic couplings are antiferromagnetic between CuII and between GdIII ions, while they are ferromagnetic between CuII and GdIII ions. AC magnetic susceptibility studies for 1 and 2 indicated that both complexes exhibit frequency dependent χ′′ signals at low temperature, but no χ′′ peaks were observed, which may be due to the deviation from ideal geometry for HoIII in 1 and DyIII in 2 and the presence of weak magnetic couplings between paramagnetic ions within the two complexes. For 3, the ac magnetic susceptibilities with zero dc fields show no frequency dependent χ′′ signals because of the isotropy of GdIII. The orientation of the easy magnetization axes of two DyIII in 2 was estimated using the Magellan program, indicating that the magnetic anisotropy axes for Dy1 and Dy2 are almost perpendicular with the angle of 86.630°. more...
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- 2019
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24. Sequential recovery of Cu(II), Cr(III), and Zn(II) from electroplating sludge leaching solution by an on-line biosorption method with dosage controlling
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Jing Wang, Ru-yi Zhou, Jun-xia Yu, Hui-sheng Wang, Qiu-yan Guo, Ke-qi Liu, Hao-dong Chen, and Ru-An Chi
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Renewable Energy, Sustainability and the Environment ,Strategy and Management ,Building and Construction ,Industrial and Manufacturing Engineering ,General Environmental Science - Published
- 2022
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25. Field-induced single molecule magnet behavior of a DyIII-NaI one-dimensional chain extended by acetate ions
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Cheng-Ling Yin, Zhao-Bo Hu, Zaichao Zhang, Yong Chen, You Song, Bi-Tian Xia, Hui-Sheng Wang, Zhi-Quan Pan, and Qiao-Qiao Long
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Materials science ,010405 organic chemistry ,Ligand ,Infrared spectroscopy ,010402 general chemistry ,01 natural sciences ,0104 chemical sciences ,Ion ,Inorganic Chemistry ,chemistry.chemical_compound ,Crystallography ,chemistry ,Diethylenetriamine ,Atom ,Materials Chemistry ,Single-molecule magnet ,Physical and Theoretical Chemistry ,Anisotropy ,Acetonitrile - Abstract
A novel DyIII-NaI one-dimensional chain, namely [DyIIINaI(L)(CH3CO2)2]n·2CH3CN (1, H2L = N1,N3‑bis(3‑methoxysalicylidene)diethylenetriamine), was synthesized by treating H2L, di-2-pyridyl ketone (dpk), and NaHCO3 with Dy(CH3CO2)2·6H2O in acetonitrile. Complex 1 was characterized by elemental analyses, IR spectroscopy, single-crystal X-ray diffraction analyses and magnetic properties. Structural analyses revealed that 1 consists of a neutral one-dimensional (1D) chain. In each [DyNa] unit, one DyIII and one NaI ions are bridged by two phenoxido O atoms from one L2− ligand and one carboxyl O atom from one CH3CO2−. Moreover, the [DyNa] units were further connected by two carboxyl O atoms from another CH3CO2−. The magnetic studies revealed that 1 exhibits the field-induced single molecule magnet behavior with an effective energy of 13.21 K. The orientation of the anisotropy axes for the DyIII in 1 was estimated by Magellan program, indicating that the directionality of the anisotropic axes is almost collinear to the Dy1-O8 bond, with an angle of 3.085°. more...
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- 2018
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26. Identification of metabolite biomarkers for L-DOPA-induced dyskinesia in a rat model of Parkinson’s disease by metabolomic technology
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Lu Yao, Ge-Juan Zhang, Yi-Na Sun, Li Zhang, Yong Wang, Jian Liu, Cheng-Xue Du, and Hui-Sheng Wang
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Male ,0301 basic medicine ,Dyskinesia, Drug-Induced ,Parkinson's disease ,Apomorphine ,genetic structures ,Polyunsaturated Alkamides ,Metabolite ,Arachidonic Acids ,Striatum ,Motor Activity ,Pharmacology ,Glycerides ,Antiparkinson Agents ,Levodopa ,Rats, Sprague-Dawley ,Pathogenesis ,03 medical and health sciences ,Behavioral Neuroscience ,chemistry.chemical_compound ,0302 clinical medicine ,Metabolomics ,Parkinsonian Disorders ,Animals ,Medicine ,Oxidopamine ,Cannabinoid Receptor Agonists ,business.industry ,medicine.disease ,Sphingolipid ,Endocannabinoid system ,Corpus Striatum ,eye diseases ,body regions ,Disease Models, Animal ,030104 developmental biology ,chemistry ,Dyskinesia ,Dopamine Agonists ,Metabolome ,sense organs ,medicine.symptom ,business ,Biomarkers ,030217 neurology & neurosurgery ,Endocannabinoids - Abstract
L-DOPA-induced dyskinesia (LID) is a frequent complication of chronic L-DOPA therapy in the clinical treatment of Parkinson's disease (PD). The pathogenesis of LID involves complex molecular mechanisms in the striatum. Metabolomics can shed light on striatal metabolic alterations in LID. In the present study, we compared metabolomics profiles of striatum tissue from Parkinsonian rats with or without dyskinetic symptoms after chronic L-DOPA administration. A liquid chromatography-mass spectrometry based global metabolomics method combined with multivariate statistical analyses were used to detect candidate metabolites associated with LID. 36 dysregulated metabolites in the striatum of LID rats, including anandamide, 2-arachidonoylglycerol, adenosine, glutamate and sphingosine1-phosphate were identified. Furthermore, IMPaLA metabolite set analysis software was used to identify differentially regulated metabolic pathways. The results showed that the metabolic pathways of "Retrograde endocannabinoid signaling", "Phospholipase D signaling pathway", "Glycerophospholipid metabolism" and "Sphingolipid signaling", etc. were dysregulated in LID rats compared to non-LID controls. Moreover, integrated pathway analysis based on results from the present metabolomics and our previous gene expression data in LID rats further demonstrates that aberrant "Retrograde endocannabinoid signaling" pathway might be involved in the development of LID. The present results provide a new profile for the understanding of the pathological mechanism of LID. more...
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- 2018
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27. Synthesis and electrocatalytic reactivity for water oxidation of two cerium complexes
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Changneng Chen, Mei Wang, Yuhua Fan, Tian-Xiang Lan, Xia Zhang, and Hui-Sheng Wang
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chemistry.chemical_element ,02 engineering and technology ,Manganese ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,Ion ,Cerium ,chemistry ,Materials Chemistry ,Reactivity (chemistry) ,Physical and Theoretical Chemistry ,0210 nano-technology ,Nuclear chemistry - Abstract
Two cerium complexes with and without manganese ion, [MnCe4(dipic)6(H2O)20][Ce(dipic)3]2·7H2O (dipic = dipicolinate) (1) and [Ce2(H2O)4(O2CMe)6][Ce(H2O)4(NO3)2(O2CMe)]2·2H2O·2MeOH (2), have been pr... more...
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- 2018
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28. Syntheses, crystal structures and magnetic properties of sandglass DyIII9 and irregular tetrahedron DyIII4 complexes
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Cheng-Ling Yin, Qiao-Qiao Long, Zi-Wei Xu, Zhi-Quan Pan, and Hui-Sheng Wang
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chemistry.chemical_classification ,Ketone ,010405 organic chemistry ,Stereochemistry ,Chemistry ,chemistry.chemical_element ,Crystal structure ,010402 general chemistry ,01 natural sciences ,0104 chemical sciences ,Square antiprism ,Ion ,Inorganic Chemistry ,Magnetic anisotropy ,Crystallography ,chemistry.chemical_compound ,Materials Chemistry ,Tetrahedron ,Dysprosium ,Hemiacetal ,Physical and Theoretical Chemistry - Abstract
The synthesis, crystal structures, and magnetic properties of a nonanuclear dysprosium complex [Dy9(μ3-OH)8(μ4-OH)2(N3)8{(py)2C(OCH3)O}8](OH)·4H2O (1, (py)2C(OCH3)OH = the hemiacetal form of di-2-pyridyl ketone) and a tetranuclear dysprosium complex [Dy4(μ4-O)(μ-N3)2(μ-OCH3)2(L)4](OH)2·3.5CH3OH (2, HL = 2-(benzothiazol-2-yl-hydrazonomethyl)-6-methoxyphenol) have been prepared and structural characterization. Nine DyIII ions in 1 form a sandglass with the eight DyIII atoms at the apexes and one DyIII ion located at the center of a square antiprism formed by eight DyIII ions, while four DyIII ions in 2 form an irregular tetrahedron. Complexes 1 and 2 have been investigated by direct current (dc) and alternating current (ac) susceptibility measurements. The ac susceptibility studies revealed that complexes 1 and 2 exhibit slow magnetic relaxation. Moreover, complex 2 shows two-step thermal magnetic relaxation with their energy barriers of about 15 K and 2.68 K, respectively. The orientations of the magnetic anisotropy of DyIII ions in 1 and 2 were also estimated by electrostatic calculations. more...
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- 2018
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29. Spinal 5-HT2A receptor is involved in electroacupuncture inhibition of chronic pain
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Xiao-Cui Yuan, Yu-Ying Wang, Li-Xia Tian, Xiang-Ji Yan, Yi-Xiao Guo, Yu-Long Zhao, Sani S Baba, Hong Jia, Hui-Sheng Wang, Man Li, and Fu-Quan Huo
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Cellular and Molecular Neuroscience ,Anesthesiology and Pain Medicine ,Molecular Medicine - Abstract
Knee osteoarthritis (KOA) is a highly prevalent, chronic joint disorder, and it is a typical disease which can develop chronic pain. Our previous study has proved that endocannabinoid (2-AG)-CB1R-GABA-5-HT pathway is involved in electroacupuncture (EA) mediated inhibition of chronic pain. However, it is still unclear which among the 5-HT receptor subtype is involved in EA evoked 5-HT mediated inhibition of chronic pain in the dorsal spinal cord. 5-HT2A is a G protein-coupled receptor and it is involved in 5-HT descending pain modulation system. We found that EA treatment at frequency of 2 Hz +1 mA significantly increased the expression of 5-HT2A receptor in the dorsal spinal cord and intrathecal injection of 5-HT2A receptor antagonist or agonist reversed or mimicked the analgesic effect of EA in each case respectively. Intrathecal injection of a selective GABAA receptor antagonist Bicuculline also reversed the EA effect on pain hypersensitivity. Additionally, EA treatment reversed the reduced expression of GABAA receptor and KCC2 in the dorsal spinal cord of KOA mice. Furthermore, we demonstrated that intrathecal 5-HT2A receptor antagonist/agonist reversed or mimicked the effect of EA up-regulate of KCC2 expression, respectively. Similarly, intrathecal injection of PLC and PKC inhibitors prevented both anti-allodynic effect and up-regulation of KCC2 expression by EA treatment. Our data suggest that EA treatment up-regulated KCC2 expression through activating 5-HT2A-Gq-PLC-PKC pathway and enhanced the inhibitory function of GABAA receptor, thereby inhibiting chronic pain in a mouse model of KOA. more...
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- 2022
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30. Two tetranuclear 3d–4f heterometal complexes Mn2Ln2 (Ln = Dy, Gd): synthesis, structure, magnetism, and electrocatalytic reactivity for water oxidation
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Hui-Sheng Wang, Changneng Chen, Mei Wang, Tian-Xiang Lan, Wei-Song Gao, and Yuhua Fan
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Lanthanide ,010405 organic chemistry ,Metal ions in aqueous solution ,chemistry.chemical_element ,General Chemistry ,Manganese ,Overpotential ,010402 general chemistry ,Electrochemistry ,01 natural sciences ,Magnetic susceptibility ,Catalysis ,0104 chemical sciences ,Metal ,Crystallography ,chemistry ,visual_art ,Materials Chemistry ,visual_art.visual_art_medium ,Reactivity (chemistry) - Abstract
In this present study, two Mn/Ln clusters, [Mn2Ln2(O2CMe)6(pdmH)2L](NO3)·H2O (Ln = Dy (1), Gd (2)), have been synthesized and experimentally investigated by X-ray crystallography, PXRD, magneto- and electrochemistry. By X-ray analysis, it is shown that the two complexes are isomorphous, both possessing one [MnIIMnIIILnIII2(μ3-O)2]6+ core with four metal atoms in one plane arranged in a butterfly conformation. This is the first time that mixed-valent manganese (MnII and MnIII) and LnIII heterometal tetranuclear complexes have been isolated and characterized. Magnetic susceptibility measurements reveal that compounds 1 and 2 both display overall weak ferromagnetic exchanges between the metal ions within the clusters. The temperature dependencies of the out-of-phase (χM′) and in-phase (χM′) ac susceptibility signals exhibit no significant frequency-dependency for compounds 1 and 2, which suggests that the two complexes may not be SMMs. Electrochemical studies indicate that compounds 1 and 2 can both catalyze water oxidation at a potential of ∼1.70 V with an overpotential of ∼880 mV vs. NHE, which could be due to a cooperative catalytic effect between the manganese and lanthanide ions. more...
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- 2018
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31. The role and mechanism of glutamic NMDA receptor in the mechanical hyperalgesia in diabetic rats
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Jin Wang, Zhaohui Sun, Yuzhao Wang, Yuan Guo, and Hui-Sheng Wang
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Male ,Pain Threshold ,0301 basic medicine ,medicine.medical_specialty ,medicine.medical_treatment ,Intraperitoneal injection ,Glutamic Acid ,CREB ,Receptors, N-Methyl-D-Aspartate ,Diabetes Mellitus, Experimental ,Rats, Sprague-Dawley ,Random Allocation ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Diabetes mellitus ,medicine ,Animals ,Phosphorylation ,Cyclic AMP Response Element-Binding Protein ,biology ,business.industry ,Antagonist ,Glutamate receptor ,General Medicine ,Analgesics, Non-Narcotic ,Streptozotocin ,medicine.disease ,Posterior Horn Cells ,030104 developmental biology ,Endocrinology ,Neurology ,Hyperalgesia ,Touch ,Anesthesia ,biology.protein ,NMDA receptor ,Neurology (clinical) ,Dizocilpine Maleate ,medicine.symptom ,business ,Excitatory Amino Acid Antagonists ,030217 neurology & neurosurgery ,medicine.drug - Abstract
Some studies have shown that painful neuropathy is a common and costly complication of both type 1 and type 2 diabetes mellitus, and glutamate is involved in the process although the mechanisms are not clear. The purpose of the present study was to investigate the effect of N-methyl-D-aspartate (NMDA) receptor on mechanical hyperalgesia in diabetic rats and the possible mechanism.Diabetic rat model was established by intraperitoneal injection of streptozotocin (STZ, 1%, 70 mg/kg) once, and evaluated by the change in the fasting blood glucose. The mechanical hyperalgesia was estimated by mechanical withdrawal threshold (MWT) using a set of calibrated Von Frey's filaments. In addition, the expressions of phosphorylated NMDA NR1 and phosphorylated cAMP response element binding protein (pCREB) in L4/L5 dorsal horns of spinal cord were observed.Behavioral results showed that MK-801, an antagonist of NMDA receptor, could reduce the proportion of mechanical hyperalgesia in diabetic rats from 76.67 to 20.00%. Meanwhile, the mean MWTs in STZ group or saline-treated STZ group decreased significantly at 3-8 week, while, the MWTs in MK-801 treated STZ group were significant higher than those in STZ or saline-treated STZ group. In addition, the expressions of NMDA NR1 and pCREB in L4/5 dorsal horns of spinal cord were significant higher in diabetic rats, and MK-801 down-regulated their expressions partly.All these results suggested that NMDA receptor and pCREB in the spinal cord were involved in the regulation of mechanical hyperalgesia in diabetic rats. more...
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- 2017
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32. Synthesis, crystal structures and magnetic properties of a series of chair-like heterometallic [Fe
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Hui-Sheng, Wang, Qiao-Qiao, Long, Zhao-Bo, Hu, Lin, Yue, Feng-Jun, Yang, Cheng-Ling, Yin, Zhi-Quan, Pan, Yi-Quan, Zhang, and You, Song
- Abstract
Four chair-like hexanuclear Fe-Ln complexes containing mixed organic ligands, namely, [Fe
- Published
- 2019
33. Regulation of magnetic relaxation behavior by replacing 3d transition metal ions in [M
- Author
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Hui-Sheng, Wang, Cheng-Ling, Yin, Zhao-Bo, Hu, Yong, Chen, Zhi-Quan, Pan, You, Song, Yi-Quan, Zhang, and Zai-Chao, Zhang
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Four tetranuclear 3d-4f complexes, namely [Fe
- Published
- 2019
34. Involvement of the Dorsal Hippocampus 5-HT1A Receptors in the Regulation of Depressive-Like Behaviors in Hemiparkinsonian Rats
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Yi-Fan, Jiang, Jian, Liu, Jie, Yang, Yuan, Guo, Wei, Hu, Jin, Zhang, Xue-Mei, La, Wen, Xie, Hui-Sheng, Wang, and Li, Zhang
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Male ,8-Hydroxy-2-(di-n-propylamino)tetralin ,Habenula ,Behavior, Animal ,Depression ,Pyridines ,Medial Forebrain Bundle ,Prefrontal Cortex ,Parkinson Disease ,Serotonin 5-HT1 Receptor Agonists ,Amygdala ,Hippocampus ,Piperazines ,Rats ,Rats, Sprague-Dawley ,Disease Models, Animal ,Receptor, Serotonin, 5-HT1A ,Animals ,Serotonin Antagonists - Abstract
Depression is one of the most common neuropsychiatric disturbances in Parkinson's disease (PD), but its pathophysiology is not definite. Lines of evidence have indicated that the hippocampus and serotonin 1A (5-HT1A) receptors are related to the regulation of depression.The purpose of the present study was to observe the effect of 5-HT1A receptors in the dorsal hippocampus (dHIP) on PD-related depression in rats.Unilateral 6-hydroxydopamine lesioning of the medial forebrain bundle (MFB) was used to establish the hemiparkinsonian rat model. The effects of intra-dHIP injection of the 5-HT1A receptor -agonist 8-hydroxy-2-(dipropylamino)tetralin hydrobromide (8-OH-DPAT) or antagonist WAY-100635 on depressive-like behaviors were observed in sucrose preference and forced swim tests in control and lesioned rats. Monoamine levels including dopamine (DA), 5-HT, and noradrenaline (NA) in depression-related brain regions were determined by a neurochemical method in all groups.Behavioral results showed that MFB lesions induced depressive-like behaviors. Intra-dHIP injection of 8-OH-DPAT produced antidepressant effects, while WAY-100635 induced or increased the depressive-like behaviors in both control and the lesioned rats. Neurochemical results found that intra-dHIP injection of 8-OH-DPAT significantly increased DA and 5-HT levels in the medial prefrontal cortex (mPFC), lateral habenula (LHb), ventral hippocampus and amygdala in the lesioned group and decreased NA levels in the mPFC and LHb in the control group. Moreover, after injection of WAY-100635, NA levels in all these regions of the lesioned group were significantly increased.These findings suggest that hippocampal 5-HT1A receptors regulate depression and PD-related depression by neurochemical mechanisms. more...
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- 2019
35. Serotonin
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Ye, Liu, Jian, Liu, Si Rui, Jiao, Xin, Liu, Yuan, Guo, Jin, Zhang, Jie, Yang, Wen, Xie, Hui Sheng, Wang, and Li, Zhang
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Male ,Neurons ,8-Hydroxy-2-(di-n-propylamino)tetralin ,Serotonin ,Pyridines ,Dopamine ,Medial Forebrain Bundle ,Prefrontal Cortex ,Parkinson Disease ,Hippocampus ,Piperazines ,Temporal Lobe ,Rats ,Serotonin Receptor Agonists ,Rats, Sprague-Dawley ,Disease Models, Animal ,Memory, Short-Term ,Parkinsonian Disorders ,Memory ,Receptor, Serotonin, 5-HT1A ,Animals ,Habituation, Psychophysiologic - Abstract
Although the dorsal hippocampus (dHPC) and serotonin
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- 2019
36. Activation and blockade of dorsal hippocampal Serotonin
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Kun Cheng, Liu, Yuan, Guo, Jin, Zhang, Li, Chen, Yi Wei, Liu, Shu Xuan, Lv, Wen, Xie, Hui Sheng, Wang, Yu Ming, Zhang, and Li, Zhang
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Male ,Rats, Sprague-Dawley ,Disease Models, Animal ,Serotonin ,Sulfonamides ,Anti-Anxiety Agents ,Dopamine ,Receptors, Serotonin ,Animals ,Parkinson Disease ,Anxiety ,Piperazines - Published
- 2019
37. Two Trinuclear Cu
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Jin-Miao, Wang, Ya-Rong, Liu, Xue-Yang, Mao, Ning-Ning, Shi, Xia, Zhang, Hui-Sheng, Wang, Yu-Hua, Fan, and Mei, Wang
- Abstract
Two trinuclear copper phosphonate complexes, [Cu
- Published
- 2019
38. Activation and Blockade of Serotonin-4 Receptors in the Lateral Habenula Produce Antidepressant Effects in the Hemiparkinsonian Rat
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Jin Zhang, Tao Wang, Cheng-Xue Du, Yuan Guo, Wen Xie, Hui-Sheng Wang, Li Zhang, Jian Liu, and Shu-Xuan Lv
- Subjects
medicine.medical_specialty ,Serotonin ,Serotonin 5-HT4 Receptor Antagonists ,Dopamine ,Hippocampus ,Prefrontal Cortex ,Substantia nigra ,chemistry.chemical_compound ,Norepinephrine ,Serotonin 5-HT4 Receptor Agonists ,Neurochemical ,Internal medicine ,medicine ,Animals ,Neurotransmitter ,Biological Psychiatry ,Habenula ,Behavior, Animal ,Chemistry ,Pars compacta ,Depression ,Parkinson Disease ,Antidepressive Agents ,Rats ,Psychiatry and Mental health ,Disease Models, Animal ,Neuropsychology and Physiological Psychology ,Endocrinology ,Monoamine neurotransmitter ,medicine.drug - Abstract
Background: The 5-hydroxytryptamine (5-HT) neurotransmitter system and lateral habenula (LHb) are involved in the regulation of depression, while the mechanisms remain to be clarified. Objectives: The effects and possible mecha-nism underlying activation or blockade of 5-HT4 receptors (5-HT4Rs) in the LHb in depression were investigated by behavioral and neurochemical methods based on a Parkinson’s disease (PD) rat model. Method: 6-Hydroxydopamine (6-OHDA) was injected unilaterally into the substantia nigra pars compacta to establish the PD rat model. The depressive-like behaviors were measured by the forced swimming test (FST) and sucrose preference test (SPT). The concentrations of dopamine (DA), noradrenaline (NA) and 5-HT in the related brain regions were measured by a neurochemical method. Results: The 6-OHDA lesions increased the immobility time in the FST and decreased the sucrose consumption in the SPT, suggesting the induction of depressive-like behaviors. Intra-LHb injection of BIMU-8 (5-HT4R agonist) or GR113808 (5-HT4R antagonist) produced antidepressant effects in the lesioned rats. Intra-LHb injection of BIMU-8 significantly increased the DA levels in the medial prefrontal cortex (mPFC) and ventral hippocampus (vHip), increased the 5-HT level in the mPFC and decreased the NA level in the vHip only in the lesioned rats, while intra-LHb injection of GR113808 changed DA, NA and 5-HT levels in the mPFC, LHb and vHip in both sham and the lesioned rats. Conclusions: All these results suggest that activation or blockade of the LHb 5-HT4Rs produce antidepressant effects in the 6-OHDA-lesioned rats, which are related to the changes of monoamines in the limbic and limbic-related regions. more...
- Published
- 2019
39. Activation and blockade of serotonin
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Yuan, Guo, Li, Zhang, Jin, Zhang, Cheng-Xue, Du, Shu-Xuan, Lv, Tao, Wang, Hui-Sheng, Wang, Wen, Xie, and Jian, Liu
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Male ,Habenula ,Serotonin ,Serotonin 5-HT4 Receptor Antagonists ,Sulfonamides ,Indoles ,Dose-Response Relationship, Drug ,Microinjections ,Dopamine ,Brain ,Bridged Bicyclo Compounds, Heterocyclic ,Rats ,Substantia Nigra ,Norepinephrine ,Serotonin 5-HT4 Receptor Agonists ,Memory, Short-Term ,Parkinsonian Disorders ,Animals ,Benzimidazoles ,Receptors, Serotonin, 5-HT4 ,Maze Learning ,Oxidopamine - Published
- 2019
40. Recent advances in 3d-4f magnetic complexes with several types of non-carboxylate organic ligands
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Hui-Sheng Wang, Zhi-Quan Pan, Ke Zhang, and You Song
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Steric effects ,Spintronics ,010405 organic chemistry ,Chemistry ,Ligand ,010402 general chemistry ,01 natural sciences ,0104 chemical sciences ,Ion ,Inorganic Chemistry ,Metal ,chemistry.chemical_compound ,Computational chemistry ,visual_art ,Magnet ,Materials Chemistry ,visual_art.visual_art_medium ,Molecule ,Carboxylate ,Physical and Theoretical Chemistry - Abstract
Since 1993, single molecule magnets (SMMs) have received a wide attention for their potential applications in high-density information storage device, quantum computer and spintronics. Particularly, since a CuII2TbII2 complex was found to possess slow magnetic relaxation behavior in 2004, 3d-4f heterometallic complexes are being investigated because they can provide the moderate magnetic couplings between 3d and 4f ions and can provide the significant single-ion magnetic anisotropies of 4f ions, which are in favor of improving SMM performance. Choosing an appropriate organic ligand with ligating atoms linked with 3d and 4f ions simultaneously is a key to synthesize 3d-4f complexes. However, synthesizing 3d-4f complexes by employing two kinds of non-carboxylate organic ligands has received little attention. We believe that the metal core topologies, the magnetic couplings, coordination geometries of 4f ions and the magnetic relaxation behavior of the 3d-4f complexes could be modulated by employing several types of non-carboxylate organic ligands due to the large steric effects between the non-carboxylate organic ligands. Based on the considerations, in recent years, we concentrated on the investigations of the 3d-4f complexes with several types of non-carboxylate organic ligands. In this review, we will present a summary of the 3d-4f complexes reported by us. The studies indicate that the metal core topologies and the magnetic couplings of the obtained 3d-4f complexes were indeed regulated, and most of the complexes possess SMM behavior. Finally, we provided some suggestions to further improve the SMM performance of the 3d-4f complexes. more...
- Published
- 2021
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41. Syntheses, crystal structures, and magnetic properties of a family of heterometallic octanuclear [Cu6Ln2] (Ln = Dy(<scp>iii</scp>), Tb(<scp>iii</scp>), Ho(<scp>iii</scp>), Er(<scp>iii</scp>), and Gd(<scp>iii</scp>)) complexes
- Author
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Zhi-Yong Huang, Feng-Jun Yang, Zhi-Quan Pan, Hui-Sheng Wang, Wei Chen, and Qiao-Qiao Long
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chemistry.chemical_classification ,Ketone ,010405 organic chemistry ,Inorganic chemistry ,General Chemistry ,Crystal structure ,010402 general chemistry ,01 natural sciences ,Catalysis ,0104 chemical sciences ,chemistry.chemical_compound ,Crystallography ,Ferromagnetism ,chemistry ,Triethanolamine ,Materials Chemistry ,medicine ,Molecule ,Isostructural ,Acetonitrile ,Triethylamine ,medicine.drug - Abstract
A new family of octanuclear Cu–Ln complexes, [Cu6Ln2(tea)2{(py)2CO2}3Cl6]·xH2O (Ln = Dy (1), Tb (2), Ho (3), Er (4), Gd (5); x = 1 for 1, 3 and 5, x = 0 for 2 and x = 7 for 4; (py)2CO2H2 = the gem-diol form of di-2-pyridyl ketone, teaH3 = triethanolamine), has been synthesized and characterized by single-crystal X-ray diffraction, elemental analyses, IR and magnetic properties. These complexes are all isostructural and were obtained by following a self-assembly reaction involving CuCl2·2H2O, Ln(NO3)3·6H2O, di-2-pyridyl ketone, triethanolamine and triethylamine in acetonitrile at room temperature. Single-crystal X-ray diffraction analyses indicate that the LnIII ions in these complexes are seven-coordinate, which is rare in 3d–4f complexes and 4f complexes. The geometries of LnIII in these complexes severely deviate from capped octahedrons. Moreover, coordination sites of Ln were occupied by two (py)2CO22− and one tea3− ligands, without the presence of coordinated solvent molecules such as H2O and small anions such as NO3− ions, which is also rare in 4f ions complexes. The direct-current magnetic susceptibilities show that the ferromagnetic coupling interactions between CuII and Ln ions are presented by fitting the data of 1/χMversus T using the Curie–Weiss law and fitting the data of χMT versus T of 5 (Gd) using PHI program. AC magnetic measurements of 1–5 without dc field and 2000 Oe dc fields show no temperature- and frequency-dependent signals, which may be due to the low symmetry of the coordination configuration of Ln in these complexes. more...
- Published
- 2017
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42. Activation and blockade of serotonin6 receptors in the dorsal hippocampus enhance T maze and hole-board performance in a unilateral 6-hydroxydopamine rat model of Parkinson's disease
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Hui Sheng Wang, Jun Yi Li, Cheng Xue Du, Li Bo Li, Li Zhang, Yu-Ming Zhang, Hui Hui Tan, Kun Cheng Liu, Jin Zhang, and Wen Xie
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0301 basic medicine ,Hydroxydopamine ,medicine.medical_specialty ,Chemistry ,General Neuroscience ,Hippocampus ,Striatum ,T-maze ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Endocrinology ,Dopamine ,Internal medicine ,medicine ,Neurology (clinical) ,Serotonin ,Medial forebrain bundle ,Molecular Biology ,Neuroscience ,030217 neurology & neurosurgery ,5-HT receptor ,Developmental Biology ,medicine.drug - Abstract
The role of dorsal hippocampus (DH) serotonin6 (5-HT6) receptors in memory is unknown, particularly in memory impairment of Parkinson's disease. We tested here effects of activation and blockade of DH 5-HT6 receptors on working and hippocampus-dependent memories in rats with unilateral 6-hydroxydopamine lesions of the medial forebrain bundle. The lesion induced working and hippocampus-dependent memory impairments as measured by the T-maze rewarded alternation and hole-board tests, and decreased dopamine (DA) levels in the striatum, medial prefrontal cortex (mPFC), DH and amygdala. Intra-DH injection of 5-HT6 receptor agonist WAY208466 (1.5, 3 and 6µg/rat) did not change choice accuracy and the number of head-dippings when re-exposure to hole-board in sham-operated rats, while 5-HT6 receptor antagonist SB258585 (4µg/rat) increased choice accuracy and decreased the number of head-dippings. In the lesioned rats, both WAY208466 (3 and 6µg/rat) and SB258585 (2 and 4µg/rat) increased choice accuracy and decreased the number of head-dippings. Neurochemical results showed that intra-DH injection of WAY208466 or SB258585 produced significant effects on DA and noradrenaline (NA) levels in the mPFC (WAY208466: sham-operated, NA -44%; lesioned, DA 522%, NA -47%; SB258585: sham-operated, DA 72%, NA 85%; lesioned, DA -68%), DH (WAY208466: lesioned, DA 427%; SB258585: sham-operated, DA 119%, NA 206%) and amygdala (WAY208466: sham-operated, NA -28%; lesioned, DA 302%; SB258585: sham-operated, NA 183%); however, 5-HT levels in these brain regions were not changed. These findings suggest DA depletion plays a key role in working and hippocampus-dependent memory impairments, and 5-HT6 receptors in the DH are involved in the regulation of the memories. more...
- Published
- 2016
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43. Synthesis, crystal structures and magnetic properties of a 1D chain based on trinuclear Cu subunits and a Cu4Dy2 complex
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Zhi-Quan Pan, Ke Zhang, Jia Wang, Zhao-Bo Hu, Yong Chen, You Song, and Hui-Sheng Wang
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chemistry.chemical_classification ,Ketone ,010405 organic chemistry ,Ligand ,chemistry.chemical_element ,Crystal structure ,010402 general chemistry ,01 natural sciences ,Copper ,0104 chemical sciences ,Inorganic Chemistry ,chemistry.chemical_compound ,Magnetization ,Crystallography ,chemistry ,Ferromagnetism ,Materials Chemistry ,Antiferromagnetism ,Physical and Theoretical Chemistry ,Triethylamine - Abstract
A one-dimensional (1D) chain [Cu3(HL)2(N3)(Mtta)]n.0.5CH3CN (1, H3L = 2-((2-hydroxybenzylidene)amino)propane-1,3-diol and Mtta = 5-methyl tetrazolate) and a Cu4Dy2 complex [Cu4Dy2{(py)2CO2}2{(py)2C(OH)O}2(CH3COO)4(N3)4].3CH3CN (2, (py)2C(OH)2 = the gem-diol form of di-2-pyridyl ketone) were obtained by the assemblies of the H3L ligand and Dy(NO3)3·5H2O with copper nitrate or with copper acetate and di-2-pyridyl ketone under the MeCN solution containing triethylamine or containing NaOH. In 1, three CuII ions were linked into a trinuclear Cu unit by three neighboring N atoms of Mtta ligand and two alkoxido-type O atoms from two HL2− ligands, then these units were further linked into a one-dimensional (1D) chain by two phenoxido O atoms from two HL2− ligands. In 2, two CuII and two DyIII ions formed a butterfly-type topology, which was further linked another two CuII by the O atoms from (py)2CO22– or from acetate ligands. Magnetic studies indicated that, in 1, the magnetic coupling through the paths of Cu N N Cu and Cu-Oalkoxido-Cu is antiferromagnetic (J1 = −14.81 cm−1), and its value was first determined in the polynuclear Cu complexes containing Mtta ligand. However, the magnetic coupling through the path of Cu-Ophenoxido-Cu is ferromagnetic (J2 = 24.61 cm−1). Magnetic studies revealed that 1 exhibits slow magnetic relaxation behavior, with an energy barrier Ueff of 6.06 K. The orientations of the easy magnetization axes of DyIII ions in 2 was estimated by Magellan program, indicating that the easy axes of DyIII in 2 are roughly aligned along alkoxido-type O atoms (O3 and O3a), which is slightly longer than other Dy-O distances. more...
- Published
- 2021
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44. A water stable layered Tb(iii) polycarboxylate with high proton conductivity over 10
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Lu, Feng, Hui-Sheng, Wang, Hai-Long, Xu, Wen-Tao, Huang, Tian-Yu, Zeng, Qing-Rong, Cheng, Zhi-Quan, Pan, and Hong, Zhou
- Abstract
An unprecedented Tb(iii) polycarboxylate, {[Tb4(TTHA)2(H2O)4]·7H2O}n (1), has been synthesized. It possesses an efficient proton transfer pathway formed by water molecules and carboxyl groups, which exhibits proton conductivity over 10-2 S cm-1 at 295-358 K and 98% relative humidity. more...
- Published
- 2019
45. Single molecule magnet behaviors of Zn
- Author
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Cheng-Ling, Yin, Zhao-Bo, Hu, Qiao-Qiao, Long, Hui-Sheng, Wang, Jing, Li, You, Song, Zai-Chao, Zhang, Yi-Quan, Zhang, and Zhi-Quan, Pan
- Abstract
In this work, we report the syntheses, crystal structures and magnetic properties of three novel Zn-Ln mixed metal complexes, namely [Zn4Dy2(L1)2(L2)2(N3)2]Cl2·2H2O (1), [Zn4Tb2(L1)2(L2)2(Cl)2][ZnN3Cl3]·2H2O (2), and [Zn4Gd2(L1)2(L2)2(Cl)2][ZnN3Cl3]·2H2O (3), in which L12- and L23- were formed from the ligand L [L = N1,N3-bis(3-methoxysalicylidene)diethylenetriamine] through in situ reactions. Interestingly, carbon dioxide in air was absorbed in the process of forming carbamate ligand L23-; this can be ascribed to the insertion of CO2 into M-N amide bonds. Moreover, 1 and 2 represent the first series of 3d-4f SMMs containing carbamate ligands by fixation of CO2 in air. Single-crystal X-ray diffraction analyses reveal that the crystal structures of 1 and 2 are anion-dependent, i.e., the apical positions of the two ZnII ions in 1 and 2 are occupied by an N atom of N3- and by Cl-, respectively. However, the topologies of 2 and 3 are similar. Two ZnII ions and one LnIII (Ln = Dy (1), Tb (2) and Gd (3)) form nearly linear trinuclear [Zn2Ln] units which are double-bridged by two L23- ligands. Magnetic studies reveal that two complexes show single molecule magnet behavior under a direct current (dc) field, with effective energy barriers (Ueff) of 30.66(5) K for 1 and 8.87(3) K for 2. Ab initio calculations reveal that the DyIII ions in 1 and the TbIII ions in 2 are axial in nature; however, a difference in the tunnel splitting of 1 and 2 leads to variation in the magnetization blockades of the two complexes. Theoretical calculations also indicate that the directions of the main magnetic axes severely deviate from the coordination atoms of the first spheres of DyIII and TbIII in 1 and 2; thus further results in poor SMM behavior of the two complexes. more...
- Published
- 2018
46. Two unprecedented decanuclear heterometallic [MnII2MnIII6LnIII2] (Ln = Dy, Tb) complexes displaying relaxation of magnetization
- Author
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Qiao-Qiao Long, Hui-Sheng Wang, Feng-Jun Yang, Zhi-Yong Huang, Zhi-Quan Pan, Wei Chen, and You Song
- Subjects
chemistry.chemical_classification ,Ketone ,010405 organic chemistry ,Inorganic chemistry ,Crystal structure ,010402 general chemistry ,01 natural sciences ,Magnetic susceptibility ,0104 chemical sciences ,Ion ,Inorganic Chemistry ,Crystallography ,Magnetization ,chemistry ,Triethanolamine ,medicine ,Molecule ,Monoclinic crystal system ,medicine.drug - Abstract
We report the syntheses, crystal structures, and magnetic properties of two 3d–4f heterometallic compounds; namely, [Mn8Ln2O2(OH)2{(py)2CO2}4(teaH)4(CH3COO)6]·6CH3CN·2H2O (LnIII = Dy (1), Tb (2); (py)2CO2H2 = the gem-diol form of di-2-pyridyl ketone, teaH3 = triethanolamine). Both compounds were prepared by the reaction of Mn(OAc)2·4H2O, Ln(NO3)3·5H2O (Ln = Dy and Tb) with the ligands di-2-pyridyl ketone and triethanolamine in MeCN, and they crystallize in the monoclinic space group C2/c. [Mn8Ln2] complexes have not been reported before, and the metallic cores of both complexes were unprecedented. In these cores, two Dy or Tb and two Mn ions comprised a well-known butterfly topology, with three of the remaining six Mn atoms each being situated on either side of the butterfly, linked through two μ3-O2− ions. Six MnIII and two MnII were in six-coordinated distorted octahedrons and two LnIII ions were in nine-coordinated distorted muffins. Interestingly, the coordination sites of LnIII ions are occupied by six O and two N atoms from two teaH2− ligands and one μ3-O2− atom, without the presence of coordinated solvent molecules such as H2O and small anions such as NO3− ions, which is rare in 3d–4f complexes. Remarkably, alternating current (ac) magnetic susceptibility measurements revealed that both complexes displayed dynamic anisotropic magnetic behaviour. The effective energy barrier (Ueff) of complex 2 was estimated to be 18.97 K through high frequency (111–9111 Hz) ac susceptibility measurements. The low symmetry of the coordination configuration of Ln3+ in 1 and 2 may be responsible for the small energy barriers of these two compounds. more...
- Published
- 2016
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47. Electrical signal propagated across acupoints along Foot Taiyang Bladder Meridian in rats
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Hui-Sheng Wang, Fanrong Yao, Zhang-Jin Zhang, Yuan Guo, Dong-Yuan Cao, and Yan Zhao
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Male ,Pain Threshold ,medicine.medical_specialty ,Urinary Bladder ,Rat model ,Electro acupuncture ,Stimulation ,Meridians ,Discharge rate ,Rats, Sprague-Dawley ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Animals ,Pharmacology (medical) ,business.industry ,General Medicine ,030205 complementary & alternative medicine ,Antidromic ,Surgery ,Sprague dawley ,Electroacupuncture ,Endocrinology ,Complementary and alternative medicine ,Medicine public health ,Meridian (astronomy) ,business ,Acupuncture Points ,030217 neurology & neurosurgery - Abstract
To investigate the electrical signals propagated along Foot Taiyang Bladder Meridian (BL) in a rat model. The experiments were performed on Dark-Agouti (DA), DA.1U and Sprague Dawley (SD) rats. The antidromic electrical stimulation was applied on the nerve innervating "Pishu" (BL 20) to mimic the acupoint electro-acupuncture (EA). The activities recording from adjacent nerve innervating acupoint "Danshu" (BL 19) or "Weishu" (BL 21) were recorded as indics for acupoint, including the mechanical threshold and discharge rate. After mimic EA on BL 20, C and Aδ units from adjacent BL 19 or BL 21 were sensitized including the decrease in mechanical threshold and increase in discharge rates in DA, DA.1U and SD rats, especially in DA rats. The average discharge rate increased from 2.40±0.26 to 6.06±0.55 and from 1.92±0.42 to 6.17±1.10 impulse/min (P more...
- Published
- 2015
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48. The major histocompatibility complex genes impact pain response in DA and DA.1U rats
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Li Li, Dong-Yuan Cao, Hui-Sheng Wang, Wen Xie, Yan Zhao, Fanrong Yao, and Yuan Guo
- Subjects
Male ,Pain Threshold ,medicine.medical_specialty ,Time Factors ,Congenic ,Pain ,Experimental and Cognitive Psychology ,Major Histocompatibility Complex ,Behavioral Neuroscience ,Nerve Fibers ,Animals, Congenic ,Formaldehyde ,Histocompatibility Antigens ,Physical Stimulation ,Internal medicine ,Threshold of pain ,medicine ,Animals ,Pain Measurement ,business.industry ,Spinal cord ,Rats ,Histocompatibility ,Disease Models, Animal ,Electrophysiology ,Endocrinology ,Nociception ,medicine.anatomical_structure ,Gene Expression Regulation ,Spinal Cord ,Hyperalgesia ,Anesthesia ,Female ,medicine.symptom ,Licking ,business ,Disinfectants - Abstract
Our recent studies have shown that the difference in basal pain sensitivity to mechanical and thermal stimulation between Dark-Agouti (DA) rats and a novel congenic DA.1U rats is major histocompatibility complex (MHC) genes dependent. In the present study, we further used DA and DA.1U rats to investigate the role of MHC genes in formalin-induced pain model by behavioral, electrophysiological and immunohistochemical methods. Behavioral results showed biphasic nociceptive behaviors increased significantly following the intraplantar injection of formalin in the hindpaw of DA and DA.1U rats. The main nociceptive behaviors were lifting and licking, especially in DA rats (P more...
- Published
- 2015
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49. Synthesis, Crystal Structures, and Magnetic Properties of Heterodimetallic Ru III –3d Coordination Compounds Based on a Meridional Tricyanoruthenium(III) Building Block
- Author
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Li-Hui Jia, Jing Xiang, Tai-Chu Lau, Song Gao, Shie-Ming Peng, and Hui-Sheng Wang
- Subjects
chemistry.chemical_classification ,Stereochemistry ,Cyanide ,Zonal and meridional ,Crystal structure ,Coordination complex ,Inorganic Chemistry ,chemistry.chemical_compound ,Bipyridine ,Paramagnetism ,Crystallography ,chemistry ,Octahedron ,Cyclen - Abstract
The synthesis, crystal structures, and magnetic properties of three cyano-bridged heterodimetallic compounds prepared from the paramagnetic RuIII building block mer-[RuIII(CN-sap)(CN)3]2– (1) are described. Complex 1 reacts with [MnII(LN5)(Cl)(H2O)]Cl and [MnII(bipy)2(Cl)2] (bipy = bipyridine) to produce the 1D zigzag chain {[RuIII(CN-sap)(CN)](μ-CN)2[MnII(LN5)]·3MeOH}n {2; LN5 = 2,13-dimethyl-3,6,9,12,18-pentaazabicyclo[12.3.1]octadeca-1(18),2,12,14,16-pentaene, CN-sapH2 = 2-hydroxy-N-(2-hydroxyphenyl)benzimidoyl cyanide} and the octanuclear compound {[RuIII(CN-sap)(CN)](μ-CN)2[MnII(bipy)(MeOH)][RuIII(CN-sap)](μ-CN)3[MnII(bipy)2]}2·8MeOH (3), respectively. The MnII centers have a pentagonal-bipyramidal environment in 2 and a distorted octahedral environment in 3. Complex 1 reacts with [NiII(cyclen)(Cl)2] (cyclen = 1,4,7,10-tetraazacyclododecane) in MeOH to produce the molecular square {[RuIII(CN-sap)(CN)](μ-CN)2[NiII(cyclen)]}2·8MeOH (4). Compounds 2 and 3 exhibit antiferromagnetic coupling between the RuIII and MnII centers, whereas 4 exhibits ferromagnetic coupling between the RuIII and NiII centers through the cyano bridges. more...
- Published
- 2015
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50. The three-body decays B ( s ) → ρf 0 ( X )→ ρπ − π + in pQCD factorization approach
- Author
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Qing-song Wang, Fa-nong Zheng, Jing Cao, Hui-sheng Wang, Xinglin Wang, and Shao-min Liu
- Subjects
Physics ,Nuclear and High Energy Physics ,Particle physics ,Meson ,010308 nuclear & particles physics ,Scalar (mathematics) ,Resonance ,Perturbative QCD ,01 natural sciences ,Theoretical physics ,Amplitude ,Factorization ,0103 physical sciences ,lcsh:QC770-798 ,lcsh:Nuclear and particle physics. Atomic energy. Radioactivity ,Invariant mass ,010306 general physics ,Scalar meson - Abstract
In this paper, we study three-body decays B ( s ) → ρ f 0 ( X ) → ρ π − π + in the perturbative QCD (pQCD) factorization approach. By using two-pion distribution amplitudes (DAs), these decays can proceed mainly via quasi-two-body channels. The Flatte model for the f 0 ( 980 ) resonance and the Breit–Wigner formula for the f 0 ( 500 ) , f 0 ( 1500 ) , and f 0 ( 1790 ) resonances are adopted to parameterize the time-like scalar form factors. We also use Bugg's model for the wide f 0 ( 500 ) as a comparison. We evaluate S-wave resonance contributions, and show the contributions to the B ( s ) → ρ π + π − decay spectrums with respect to the two-pion invariant mass M ( π + π − ) . The pQCD prediction of B → ρ f 0 ( 500 ) is B ( B 0 → ρ 0 f 0 ( 500 ) ) = 4.43 × 10 − 8 , B ( B + → ρ + f 0 ( 500 ) ) = 3.84 × 10 − 8 for Breit–Wigner model, and B ( B 0 → ρ 0 f 0 ( 500 ) ) = 4.91 × 10 − 8 , B ( B + → ρ + f 0 ( 500 ) ) = 4.07 × 10 − 8 for Bugg's model. We also predict other resonance contributions B ( B s → ρ 0 f 0 ( 980 ) ) = 8.91 × 10 − 8 , B ( B s → ρ 0 f 0 ( 1500 ) ) = 1.43 × 10 − 8 and B ( B s → ρ 0 f 0 ( 1790 ) ) = 2.78 × 10 − 9 . This study in pQCD approach can provide a ready reference to the running and forthcoming experiments. Further improvements in theories and experiments are expected so that we can understand the inner structure of the scalar mesons f 0 . more...
- Published
- 2017
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