Search

Your search keyword '"Hugo Rabier"' showing total 10 results
Start Over Author "Hugo Rabier"
10 results on '"Hugo Rabier"'

1. Economic valuation of informal care provided to people after a myocardial infarction in France

Author

Hugo Rabier, Hassan Serrier, Anne-Marie Schott, Nathan Mewton, Michel Ovize, Norbert Nighoghossian, Antoine Duclos, and Cyrille Colin

Subjects
Informal care, Myocardial infarction, Contingent valuation method, Willingness to pay, Cost, France, Public aspects of medicine, RA1-1270
Abstract

Abstract Background The aim of this study was to estimate the mean cost per caregiver of informal care during the first year after myocardial infarction event in France. Methods We used the Handicap-Santé French survey carried out in 2008 to obtain data about MI survivors and their caregivers. After obtaining the total number of informal care hours provided by caregiver during the first year after MI event, we estimated the value of informal care using the proxy good method and the contingent valuation method. Results For MI people receiving informal care, an annual mean cost was estimated at €12,404 (SD = 13,012) with the proxy good method and €12,798 (SD = 13,425) with the contingent valuation method per caregiver during the first year after myocardial infarction event. Conclusions The present study suggests that informal care should be included more widely in economic evaluations in order not to underestimate the cost of diseases which induce disability.

Published
2019
Full Text
View/download PDF

2. National cost study versus hospital cost accounting for organ recovery cost assessment in a French hospital group

Author

Abdelbaste Hrifach, Christell Ganne, Sandrine Couray-Targe, Coralie Brault, Pascale Guerre, Hassan Serrier, Hugo Rabier, Gwen Grguric, Pierre Farge, and Cyrille Colin

Subjects
Cost data source, Hospital cost accounting, National cost study, Organ recovery, Medicine (General), R5-920
Abstract

Abstract Background The choice of cost data sources is crucial, because it influences the results of cost studies, decisions of hospital managers and ultimately national directives of policy makers. The main objective of this study was to compare a hospital cost accounting system in a French hospital group and the national cost study (ENC) considering the cost of organ recovery procedures. The secondary objective was to compare these approaches to the weighting method used in the ENC to assess organ recovery costs. Methods The resources consumed during the hospital stay and organ recovery procedure were identified and quantified retrospectively from hospital discharge abstracts and the national discharge abstract database. Identified items were valued using hospital cost accounting, followed by 2010–2011 ENC data, and then weighted using 2010–2011 ENC data. A Kruskal–Wallis test was used to determine whether at least two of the cost databases provided different results. Then, a Mann–Whitney test was used to compare the three cost databases. Results The costs assessed using hospital cost accounting differed significantly from those obtained using the ENC data (Mann–Whitney; P-value

Published
2018
Full Text
View/download PDF

4. Pharmacogenetic-guided glimepiride therapy in type-2 diabetes mellitus: a cost-effectiveness study

Author

Hassan Serrier, Cécile Fokoun, Hugo Rabier, Michel Tod, Laurent Bourguignon, and Sylvain Goutelle

Subjects
0301 basic medicine, medicine.medical_specialty, Genotyping Techniques, Cost effectiveness, Cost-Benefit Analysis, Disease, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Diabetes mellitus, Genetics, Humans, Hypoglycemic Agents, Medicine, Dosing, Intensive care medicine, Cytochrome P-450 CYP2C9, Pharmacology, Polymorphism, Genetic, business.industry, Type 2 Diabetes Mellitus, Health Care Costs, medicine.disease, Glimepiride, Regimen, Sulfonylurea Compounds, Treatment Outcome, 030104 developmental biology, Diabetes Mellitus, Type 2, Molecular Medicine, business, Pharmacogenetics, medicine.drug
Abstract

The demonstration of the link between certain genetic variations and drug response has allowed the emergence of pharmacogenetics, which offers many opportunities to improve patient care. Type-2 diabetes mellitus is a disease for which several gene polymorphisms have been reported to be associated with drug response. Sulfonylureas are commonly used for the management of this disease. Genetic polymorphisms of CYP2C9, the main enzyme involved in the metabolism of sulfonylureas, have been associated with the risk of severe hypoglycaemia, particularly in poor metabolizers carrying CYP2C9 *3/*3 genotype, and especially in the case of patients treated with glimepiride. The objectives of the present study were to evaluate the potential clinical and economic outcomes of using CYP2C9 genotype data to guide the management of SU regimen in patients initiating glimepiride therapy, and to identify factors affecting the cost-effectiveness of this treatment scheme. The analysis was conducted using a decision tree, considering a 1-year time horizon, and taking as perspective that of the French national health insurance system. With pharmacogenetic-guided therapy, the cost to avoid an episode of severe hypoglycaemia event per 100 000 patients treated was €421 834. Genotyping cost was the most influential factor on the incremental cost-effectiveness ratio. In conclusion, the potential cost of CYP2C9 genotype-guided dosing for glimepiride therapy is relatively high, and associated with modest improvements with respect to the number of hypoglycaemia avoided, as compared with standard dosing. Additional economic studies are required to better specify the usefulness of CYP2C9 genotyping prior to glimepiride regimen initiation.

Published
2021

5. Patients' productivity losses and informal care costs related to ischemic stroke: a French population-based study

Author

Cyrille Colin, Laurent Derex, Julie Haesebaert, Hugo Rabier, M. Barral, Anne Termoz, Norbert Nighoghossian, Marie Viprey, H. Serrier, and Anne-Marie Schott

Subjects
Male, Population, Brain Ischemia, Cohort Studies, 03 medical and health sciences, Indirect costs, 0302 clinical medicine, Cost of Illness, Modified Rankin Scale, medicine, Humans, 030212 general & internal medicine, education, Stroke, Aged, Ischemic Stroke, education.field_of_study, business.industry, Health Care Costs, medicine.disease, Cross-Sectional Studies, Neurology, Telephone interview, Caregivers, Presenteeism, Absenteeism, Female, Neurology (clinical), Patient Care, business, 030217 neurology & neurosurgery, Demography, Cohort study
Abstract

BACKGROUND AND PURPOSE Large societal costs of stroke should not be ignored. We aimed to estimate patients' productivity losses and informal care costs during the first year after ischemic stroke. METHODS A cross-sectional survey was performed within the STROKE69 regional population-based cohort study. At 1 year post-stroke, each patient and the corresponding main informal caregiver received questionnaires followed by a telephone interview if necessary. Time losses were valued using the human capital approach and proxy good method for patients with and without a professional activity, respectively. RESULTS Among the 222 patients with ischemic stroke (58% men; mean age 68 years; and 86% with a modified Rankin Scale (mRS) score of

Published
2020

6. Myocardial infarction: Economic, health, and social impacts on informal caregivers

Author

Cyrille Colin, Michel Ovize, Hugo Rabier, Anne-Marie Schott, Antoine Duclos, Marie Viprey, Norbert Nighoghossian, Gwen Grguric, Marine Barral, Pascale Guerre, Christell Julien, Jennifer Margier, Jessica Dalaudiere, Hassan Serrier, Asma Fares, Nathan Mewton, Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), Centre de Recherche et d'Application en Traitement de l'Image et du Signal (CREATIS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-École Supérieure Chimie Physique Électronique de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL), Animal Health Department, Instituto Vasco de Investigación y Desarrollo Agrario [Derio] (NEIKER), Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de recherche pour le développement [IRD] : UR206-Centre National de la Recherche Scientifique (CNRS), Centre d'études et de recherche sur les services de santé et la qualité de vie (CEReSS), Aix Marseille Université (AMU), Assistance Publique - Hôpitaux de Marseille (APHM), Department of Cardiology, Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (CREATIS), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Health Service and Performance Research (HESPER), Université de Lyon-Université de Lyon, Géosciences Paris Sud (GEOPS), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), Université de Lyon-Université de Lyon-École Supérieure de Chimie Physique Électronique de Lyon (CPE)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université de Toulouse (UT)-Université de Toulouse (UT), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), and ANR-16-RHUS-0009,MARVELOUS,MARVELOUS(2016)

Subjects
Male, Multivariate analysis, media_common.quotation_subject, [SDV]Life Sciences [q-bio], Population, 03 medical and health sciences, 0302 clinical medicine, Willingness to pay, Surveys and Questionnaires, Medicine, Humans, Interpersonal Relations, 030212 general & internal medicine, Prospective Studies, Survivors, education, media_common, Aged, Aged, 80 and over, education.field_of_study, Contingent valuation, business.industry, 030503 health policy & services, Health Policy, Caregiver burden, Middle Aged, Health indicator, Economic evaluation, Informal care, 3. Good health, Myocardial infarction, Feeling, Caregivers, Health impact, Social impact, Female, France, Patient Care, 0305 other medical science, business, Demography
Abstract

ObjectivesThe aim of the study was to measure the economic impact of informal care (IC) on caregivers assisting myocardial infarction (MI) survivors in France. Health and social impacts were also described.MethodsData from the prospective 2008 Health and Disabilities Households Survey (Enquête Handicap-Santé), carried out among the French general population, were used to obtain information about patients with MI and their informal caregivers. To estimate the approximate monetary value of IC, three methods were used: the proxy good method, opportunity cost method (OCM), and contingent valuation method (CVM). A multivariate analysis was performed to determine the associations of the IC duration and the existence of professional care with the health indicators stated by caregivers.ResultsThe analysis included data from 147 caregivers. The mean value of IC ranged from €9,679 per year using the CVM to €11,288 per year using the OCM (p> .05). The mean willingness to pay for an additional hour of IC was €10.9 (SD = 8.3). A total of 46.2 percent of caregivers reported that IC negatively affected theirs physical condition, and 46.3 percent reported that it negatively affected their psychological health. In addition, 40.1 percent declared that caregiving activity made them anxious and 38.8 percent stated they felt alone. Associations were identified between the duration of IC and feeling the need to be replaced, feeling alone and making sacrifices (p< .05).ConclusionsInformal caregiver burden may be recognized in health technology assessment in order not to underestimate the cost of strategies and to facilitate the comparability of cost-effectiveness outcomes between studies.

Published
2020

8. Quality Assessment of Reporting of Economic Evaluation in Cardiac Sugery: Has it Improved?

Author

Abdelbaste Hrifach, Cyrille Colin, Hassan Serrier, Hugo Rabier, Pascale Guerre, Jean-François Obadia, Christell Julien, Nermine Laaboub, Daniel Grinberg, Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Géosciences Paris Sud (GEOPS), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL), Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Institut de recherche pour le développement [IRD] : UR206-Centre National de la Recherche Scientifique (CNRS)-Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC), Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National de la Recherche Agronomique (INRA), Muséum national d'Histoire naturelle (MNHN)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de recherche pour le développement [IRD] : UR206-Centre National de la Recherche Scientifique (CNRS), and Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
medicine.medical_specialty, Cost-Benefit Analysis, media_common.quotation_subject, [SDV]Life Sciences [q-bio], 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Humans, Medicine, Quality (business), Cardiac Surgical Procedures, media_common, Cardiac surgery procedures, Health economics, business.industry, Quality assessment, Health Policy, Economic evaluation, Economics, Medical, Cardiac Surgery procedures, Bibliometrics, Research Design, Family medicine, Transparency (graphic), Periodicals as Topic, business, Inclusion (education), 030217 neurology & neurosurgery
Abstract

ObjectivesCardiac surgery has seen substantial scientific progress over recent decades. Health economic evaluations have become important tools for decision makers to prioritize scarce health resources. The present study aimed to identify and critically appraise the reporting quality of health economic evaluations conducted in the field of cardiac surgery.MethodsA literature search was performed to identify health economic evaluations in cardiac surgery. The consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement was used to assess the quality of reporting of studies.ResultsA total 4,705 articles published between 1981 and 2016 were identified; sixty-nine studies fulfilled the inclusion criteria. There was a trend toward a greater number of publications and reporting quality over time. Six (8.7 percent) studies were conducted between 1981 and 1990, nine (13 percent) between 1991 and 2000, twenty-four (34.8 percent) between 2001 and 2010, and thirty (43.5 percent) after 2011. The mean CHEERS score of all articles was 16.7/24; for those published between 1980 and 1990 the mean (SD) score was 10.2 (±1.4), for those published between 1991 and 2000 it was 11.2 (±2.4), between 2001 and 2010 it was 15.3 (±4.8), and after 2011 it was 19.9 (±2.9). The quality of reporting was still insufficient for several studies after 2000, especially concerning items “characterizing heterogeneity,” “assumptions,” and “choice of model.”ConclusionsThe present study suggests that, even if the quantity and the quality of health economics evaluation in cardiac surgery has increased, there remains a need for improvement in several reporting criteria to ensure greater transparency.

Published
2019

10. PCV42 MYOCARDIAL INFARCTION: ECONOMIC, HEALTH, AND SOCIAL IMPACTS ON INFORMAL CAREGIVERS

Author

G. Grguric, M. Ovize, N. Mewton, P. Guerre, C. Julien, Antoine Duclos, Marie Viprey, H. Serrier, A. Fares, M. Barral, Cyrille Colin, J. Margier, Anne-Marie Schott, Hugo Rabier, J. Dalaudiere, and Norbert Nighoghossian

Subjects
Gerontology, business.industry, Health Policy, Public Health, Environmental and Occupational Health, medicine, Myocardial infarction, medicine.disease, business
Published
2019

Catalog

Books, media, physical & digital resources
See catalog results