865 results on '"Huang, Zhi-Shu"'
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2. Disrupting the protein-protein interaction network of Hsp72 inhibits adipogenic differentiation and lipid synthesis in adipocytes
3. Identification of sanguinarine as c-MYC transcription inhibitor through enhancing the G-quadruplex-NM23-H2 interactions
4. Design, synthesis and structure-activity relationship of novel 2-pyrimidinylindole derivatives as orally available anti-obesity agents
5. Synergistic anticancer activity of HSP70 and HSF1 inhibitors in colorectal cancer cells: A new strategy for combination therapy
6. Mitochondrial RelA empowers mtDNA G-quadruplex formation for hypoxia adaptation in cancer cells
7. Regulation of VEGF gene expression by bisacridine derivative through promoter i-motif for cancer treatment
8. Constructing triazole-modified quinazoline derivatives as selective c-MYC G-quadruplex ligands and potent anticancer agents through click chemistry
9. Design, synthesis and evaluation of 2-pyrimidinylindole derivatives as anti-obesity agents by regulating lipid metabolism
10. Development of a fluorescent chemical probe with the ability to visualize nascent phase-separated stress granules
11. Syntheses and evaluation of acridone derivatives as anticancer agents targeting Kras promoter i-motif structure
12. Regulation of c-Kit gene transcription selectively by bisacridine derivative through promoter dual i-motif structures
13. Xanthone sulfonamide derivatives-A novel series of α-glucosidase inhibitors with different inhibitory types
14. Dual-color imaging of DNA and RNA simultaneously with an aggregation/monomer-based deep-red fluorescent probe
15. New Therapeutic Method for Alleviating Damage of Acute Kidney Injury Through BCL-2 Gene Promoter I-Motif.
16. 9-Bromo-2,3-diethylbenzo[de]chromene-7,8-dione (MSN54): A novel non-intercalative topoisomerase II catalytic inhibitor
17. L‐aspartate ameliorates diet‐induced obesity by increasing adipocyte energy expenditure.
18. Syntheses and evaluation of acridone-naphthalimide derivatives for regulating oncogene PDGFR-β expression
19. Efficient and rational development of a new fluorescent probe specific for RNA G-quadruplex imaging in cells
20. Recent advances in fluorescent probes for G-quadruplex nucleic acids
21. A drug-like imidazole-benzothiazole conjugate inhibits malignant melanoma by stabilizing the c-MYC G-quadruplex
22. Discovery of a promising agent IQZ23 for the treatment of obesity and related metabolic disorders
23. Design, synthesis and biological evaluation of novel perimidine o-quinone derivatives as non-intercalative topoisomerase II catalytic inhibitors
24. Pyridocarbazole alkaloids from Ochrosia borbonica: lipid-lowering agents inhibit the cell proliferation and adipogenesis of 3T3-L1 adipocyte via intercalating into supercoiled DNA
25. Bouchardatine suppresses rectal cancer in mice by disrupting its metabolic pathways via activating the SIRT1-PGC-1α-UCP2 axis
26. Syntheses and evaluation of new Quinoline derivatives for inhibition of hnRNP K in regulating oncogene c-myc transcription
27. Development of Novel N‑Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde Group.
28. Mulberry Diels-Alder-type adducts from Morus alba as multi-targeted agents for Alzheimer's disease
29. Discovery of Ingenane Diterpenoids from Euphorbia hylonoma as Antiadipogenic Agents
30. Synthesis and evaluation of 1,2,3,4-tetrahydro-1-acridone analogues as potential dual inhibitors for amyloid-beta and tau aggregation
31. Tuning the selectivity of a commercial cyanine nucleic acid dye for preferential sensing of hybrid telomeric G-quadruplex DNA
32. Synthesis, cytotoxicity and structure-activity relationship of indolizinoquinolinedione derivatives as DNA topoisomerase IB catalytic inhibitors
33. Design, synthesis and biological evaluation of novel bouchardatine analogs as potential inhibitors of adipogenesis/lipogenesis in 3T3-L1 adipocytes
34. Identification of small molecules capable of regulating conformational changes of telomeric G-quadruplex
35. Synthesis of carbazole derivatives containing chalcone analogs as non-intercalative topoisomerase II catalytic inhibitors and apoptosis inducers
36. Targeting ATP-binding site of WRN Helicase: Identification of novel inhibitors through pocket analysis and Molecular Dynamics-Enhanced virtual screening
37. Interaction of Quindoline derivative with telomeric repeat–containing RNA induces telomeric DNA-damage response in cancer cells through inhibition of telomeric repeat factor 2
38. Curcusone C induces telomeric DNA-damage response in cancer cells through inhibition of telomeric repeat factor 2
39. Synthesis and evaluation of 7-substituted-5,6-dihydrobenzo[c]acridine derivatives as new c-KIT promoter G-quadruplex binding ligands
40. Design, synthesis and evaluation of 2-arylethenyl-N-methylquinolinium derivatives as effective multifunctional agents for Alzheimer's disease treatment
41. Analogues of xanthones——Chalcones and bis-chalcones as α-glucosidase inhibitors and anti-diabetes candidates
42. Syntheses and antibacterial activity of soluble 9-bromo substituted indolizinoquinoline-5,12-dione derivatives
43. Development of an engineered carbazole/thiazole orange conjugating probe for G-quadruplexes
44. Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5′-UTR RNA G‑Quadruplexes.
45. Divergent Fluorinations of Vinylcyclopropanes: Ring‐Opening 1,5‐Hydrofluorination and Ring‐Retaining 1,2‐Difluorination
46. Design and Synthesis of Bouchardatine Derivatives as a Novel AMP-Activated Protein Kinase Activator for the Treatment of Colorectal Cancer
47. Design, synthesis and biological evaluation of 4-anilinoquinazoline derivatives as new c-myc G-quadruplex ligands
48. Accurate high-throughput identification of parallel G-quadruplex topology by a new tetraaryl-substituted imidazole
49. Blocking the binding of WT1 to bcl-2 promoter by G-quadruplex ligand SYUIQ-FM05
50. Complicated behavior of G-quadruplexes and evaluating G-quadruplexes' ligands in various systems mimicking cellular circumstance
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