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192 results on '"Huang, Li-Bin"'

3. Long-term outcome of children with acute promyelocytic leukemia: a randomized study of oral versus intravenous arsenic by SCCLG-APL group

Author

Huang, Dan-Ping, Yang, Liang-Chun, Chen, Yi-Qiao, Wan, Wu-Qing, Zhou, Dun-Hua, Mai, Hui-Rong, Li, Wan-Li, Yang, Li-Hua, Lan, He-Kui, Chen, Hui-Qin, Guo, Bi-Yun, Zhen, Zi-Jun, Liu, Ri-Yang, Chen, Guo-Hua, Feng, Xiao-Qin, Liang, Cong, Wang, Li-Na, Li, Yu, Luo, Jie-Si, Fan, Zhong, Luo, Xue-Qun, Li, Bin, Tang, Yan-Lai, Zhang, Xiao-Li, and Huang, Li-Bin

Published
2023
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7. Pan-cancer single-cell analysis reveals the heterogeneity and plasticity of cancer-associated fibroblasts in the tumor microenvironment

Author

Luo, Han, Xia, Xuyang, Huang, Li-Bin, An, Hyunsu, Cao, Minyuan, Kim, Gyeong Dae, Chen, Hai-Ning, Zhang, Wei-Han, Shu, Yang, Kong, Xiangyu, Ren, Zhixiang, Li, Pei-Heng, Liu, Yang, Tang, Huairong, Sun, Ronghao, Li, Chao, Bai, Bing, Jia, Weiguo, Liu, Yi, Zhang, Wei, Yang, Li, Peng, Yong, Dai, Lunzhi, Hu, Hongbo, Jiang, Yong, Hu, Yiguo, Zhu, Jingqiang, Jiang, Hong, Li, Zhihui, Caulin, Carlos, Park, Jihwan, and Xu, Heng

Published
2022
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8. Benefits of the Continuous Use of 6-MP/MTX with Pulses of VCR/DEX in Maintenance Therapy for Pediatric Acute Lymphoblastic Leukemia: A Report from South China Children's Leukemia Group

Author

Qiu, Kun-yin, primary, Huang, Li-Bin, additional, Mai, Hui-Rong, additional, Li, Xin-yu, additional, Tang, Yan-Lai, additional, He, Ying-yi, additional, Liao, Ning, additional, Wu, Xue-dong, additional, Yang, Li-Hua, additional, Zhou, Dun-hua, additional, Wan, Wu-qing, additional, Chen, Hui-qin, additional, Liu, Ri-yang, additional, Chen, Qi-wen, additional, Ye, Zhong-lv, additional, Long, Xing-Jiang, additional, Zhen, Zijun, additional, Wu, Bei-yan, additional, Zhang, Xiao-Li, additional, Li, Chang-gang, additional, Wang, Jia-yi, additional, He, Yunyan, additional, Feng, Xiao-Qin, additional, Yu, Li-hua, additional, Liu, Ying, additional, Liu, Si-xi, additional, Li, Chi-kong, additional, and Fang, Jian-pei, additional

Published
2024
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12. Gene Expression Network and Circ_0008012 Promote Progression in MLL/AF4 Positive Acute Lymphoblastic Leukemia

Author

Tang, Yan-Lai, primary, Su, Jia-Yin, primary, Luo, Jie-Si, primary, Zhang, Li-Dan, additional, Zheng, Li-Min, additional, Liang, Cong, additional, Wang, Li-Na, additional, Li, Yu, additional, Fan, Zhong, additional, Huang, Dan-Ping, additional, Sun, Panpan, additional, Luo, Zhenhua, additional, Qi, Ning Hao, additional, Lan, Jing-Jing, additional, Zhang, Xiao-Li, additional, Huang, Li-Bin, additional, and Luo, Xue-Qun, additional

Published
2023
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14. Single cell immunoprofile of synovial fluid in rheumatoid arthritis with TNF-α/JAK inhibitor treatment

Author

Xu, Heng, primary, Xia, Xuyang, additional, He, Chenjia, additional, Xue, Zhinan, additional, Wang, Yuelan, additional, Ren, Zhixiang, additional, Huang, Yupeng, additional, Luo, Han, additional, Chen, Hai-Ning, additional, Zhang, Weihan, additional, Huang, Li-Bin, additional, Shi, Yunying, additional, Bai, Yangjuan, additional, Cai, Pei, additional, Wang, Lanlan, additional, Zhang, Feng, additional, Qian, Maoxiang, additional, Zhang, Wei, additional, Shu, Yang, additional, Yin, Geng, additional, and Xie, Qibing, additional

Published
2023
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16. Clinical summary of pediatric acute lymphoblastic leukemia patients complicated with asparaginase-associated pancreatitis in SCCLG-ALL-2016 protocol.

Author

Wang, Jian, Jia, Wen-Guang, Yang, Li-Hua, Kuang, Wen-Yong, Huang, Li-Bin, Chen, Hui-Qin, Wang, Li-Na, Zhou, Dun-Hua, and Liao, Ning

Subjects
LYMPHOBLASTIC leukemia, ACUTE leukemia, DISEASE relapse, PANCREATITIS
Abstract

Asparaginase-associated pancreatitis (AAP) is a common and fatal complication after ASNase treatment in acute lymphoblastic leukemia(ALL). Here, a total of 1063 pediatric ALL patients treated with SCCLG-ALL-2016 regimen were collected since October 2016 to June 2020, including 35 patients with AAP. The clinical characteristics of AAP and non-AAP patients were compared. In AAP patients, the possible factors that affected the recurrence of AAP were analyzed, and the possible risk factors related to ALL-relapse were discussed. The results showed that age was a risk factor (P =.017) that affect the occurrence of AAP. In AAP patients, AAP tended to develop after the second use of PEG-ASNase (25.71%). In the follow-up chemotherapy, 17 patients re-exposed to ASNase and 7 cases developed AAP again with a percentage was 41.2%. There were no special factors that related with the recurrence of AAP. This study also found no association between the occurrence of AAP and prognosis of ALL, with the 4-year incidence of ALL relapse in AAP and non-AAP patients were 15.9% v.s.11.7% (HR: 1.009, 95% CI:0.370–2.752, P =.986), and there were no special factors that related with the ALL relapse among AAP patients. Based on the above results, the occurrence of AAP is related to age and should be vigilant after the second use of PEG-ASNase after use in pediatric ALL patients. Moreover, AAP is not associated with ALL relapse, but there is a high AAP recurrence rate when re-exposure to ASNase. [ABSTRACT FROM AUTHOR]

Published
2023
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18. Vincristine and dexamethasone pulses in addition to maintenance therapy among pediatric acute lymphoblastic leukemia (GD‐ALL‐2008): An open‐label, multicentre, randomized, phase III clinical trial

Author

Qiu, Kun‐yin, primary, Wang, Jia‐yi, additional, Huang, Li‐bin, additional, Li, Chang‐gang, additional, Xu, Lu‐hong, additional, Liu, Ri‐yang, additional, Chen, Hui‐qin, additional, Ruan, Yong‐sheng, additional, Zhen, Zi‐jun, additional, Li, Chi‐kong, additional, and Fang, Jian‐pei, additional

Published
2023
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20. Prognostic significance of CNSL at diagnosis of childhood B-cell acute lymphoblastic leukemia: A report from the South China Children’s Leukemia Group

Author

Xu, Lu-Hong, primary, Geng, Xu, additional, Liao, Ning, additional, Yang, Li-Hua, additional, Mai, Hui-Rong, additional, Wan, Wu-Qing, additional, Huang, Li-Bin, additional, Zheng, Min-Cui, additional, Tian, Chuan, additional, Chen, Hui-Qin, additional, Chen, Qi-Wen, additional, Long, Xing-Jiang, additional, Zhen, Zi-Jun, additional, Liu, Ri-Yang, additional, Li, Qiao-Ru, additional, Wu, Bei-Yan, additional, Wang, Li-Na, additional, Kong, Xian-Ling, additional, Chen, Guo-Hua, additional, Fang, Jian-Pei, additional, and Li, Yang, additional

Published
2022
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21. Differentiation Syndrome and Coagulation Disorder -- Comparison between treatment with Oral and Intravenous Arsenics in Pediatric Acute Promyelocytic Leukemia.

Author

Luo, Jie-si, primary, Zhang, Xiao-Li, additional, Huang, Dan-Ping, additional, Chen, Yi-Qiao, additional, Wan, Wu-Qing, additional, Mai, Huirong, additional, Chen, Hui-Qin, additional, Wen, Hong, additional, Liu, Ri-Yang, additional, Chen, Guohua, additional, Li, Yu, additional, Luo, Xue-Qun, additional, Tang, Yan-Lai, additional, and Huang, Li-Bin, additional

Published
2022
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24. Prognostic Value and Outcome for ETV6/RUNX1-Positive Pediatric Acute Lymphoblastic Leukemia: A Report From the South China Children’s Leukemia Group

Author

Qiu, Kun-yin, primary, Xu, Hong-gui, additional, Luo, Xue-qun, additional, Mai, Hui-rong, additional, Liao, Ning, additional, Yang, Li-hua, additional, Zheng, Min-cui, additional, Wan, Wu-qing, additional, Wu, Xue-dong, additional, Liu, Ri-yang, additional, Chen, Qi-wen, additional, Chen, Hui-qin, additional, Sun, Xiao-fei, additional, Jiang, Hua, additional, Long, Xing-jiang, additional, Chen, Guo-hua, additional, Li, Xin-yu, additional, Li, Chang-gang, additional, Huang, Li-bin, additional, Ling, Ya-yun, additional, Lin, Dan-na, additional, Wen, Chuan, additional, Kuang, Wen-yong, additional, Feng, Xiao-qin, additional, Ye, Zhong-lv, additional, Wu, Bei-yan, additional, He, Xiang-lin, additional, Li, Qiao-ru, additional, Wang, Li-na, additional, Kong, Xian-ling, additional, Xu, Lu-hong, additional, Li, Chi-kong, additional, and Fang, Jian-pei, additional

Published
2021
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40. Up-regulated miR-155 is associated with poor prognosis in childhood acute lymphoblastic leukemia and promotes cell proliferation targeting ZNF238.

Author

Liang, Cong, Li, Yu, Wang, Li-Na, Zhang, Xiao-Li, Luo, Jie-Si, Peng, Chun-Jin, Tang, Wen-Yan, Huang, Li-Bin, Tang, Yan-Lai, and Luo, Xue-Qun

Subjects
LYMPHOBLASTIC leukemia, ACUTE leukemia, CELL proliferation, PROGNOSIS, FLOW cytometry
Abstract

Acute lymphoblastic leukemia (ALL) is one of the most common malignancies in children. Our aim was to identify a novel miRNA that can predict prognosis of childhood ALL patients and explore its potential mechanism. The miRNA expression profiles of childhood ALL were analyzed using GEO database and HiSeq instruments. The expression of miR-155 was examined by RT–PCR in 42 ALL patients. To investigate the role of miR-155 in ALL, four ALL cell lines (CEM-C1, Jurkat, MOLT-3 and MOLT-4) were transfected with miR-155 mimics, miR-155 inhibitors or corresponding controls. Dual-luciferase reporter system was applied to confirm the miR-155 target ZNF238. Moreover, proliferation and apoptosis were evaluated by MTT and flow cytometry. Dataset GSE56489 and GSE23024 demonstrated that miR-155 was up-regulated and ZNF238 was down-regulated at diagnosis status of ALL. High miR-155 expression was associated with poor outcome. Overexpressed miR-155 promoted ALL cell proliferation and inhibited apoptosis. Dual-luciferase reporter result showed that miR-155 directly regulated ZNF238. Silencing ZNF238 promoted cell proliferation in ALL cells. Our research indicating that miR-155 might possess potential value as a biomarker for predicting the prognosis of individuals. However, the role of ZNF238 in childhood ALL remain unknown. In the present study, we found the possible role of ZNF238 as a new tumor suppressor in ALL, which might be necessary for the antiproliferative functions of normal cells to counteract ALL formation. Our results propose that miR-155 is in association with poor prognosis of childhood ALL. Furthermore, miR-155 could promote cell proliferation targeting ZNF238. [ABSTRACT FROM AUTHOR]

Published
2021
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43. Melatonin inhibits MLL-rearranged leukemia via RBFOX3/hTERT and NF-κB/COX-2 signaling pathways

Author

Tang, Yan-Lai, primary, Sun, Xi, additional, Huang, Li-Bin, additional, Liu, Xiao-Jian, additional, Qin, Ge, additional, Wang, Li-Na, additional, Zhang, Xiao-Li, additional, Ke, Zhi-Yong, additional, Luo, Jie-Si, additional, Liang, Cong, additional, Peng, Chun-Jin, additional, Tang, Wen-Yan, additional, Li, Yu, additional, Huang, Wenlin, additional, Luo, Xue-Qun, additional, and Deng, Wuguo, additional

Published
2019
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45. Multicenter randomized trial of arsenic trioxide and Realgar-Indigo naturalisformula in pediatric patients with acute promyelocytic leukemia: Interim results of the SCCLG-APL clinical study

Author

Yang, Ming-Hua, primary, Wan, Wu-Qing, additional, Luo, Jie-Si, additional, Zheng, Min-Cui, additional, Huang, Ke, additional, Yang, Li-Hua, additional, Mai, Hui-Rong, additional, Li, Jian, additional, Chen, Hui-Qin, additional, Sun, Xiao-Fei, additional, Liu, Ri-Yang, additional, Chen, Guo-Hua, additional, Feng, Xiaoqin, additional, Ke, Zhi-Yong, additional, Li, Bin, additional, Tang, Yan-Lai, additional, Huang, Li-Bin, additional, and Luo, Xue-Qun, additional

Published
2018
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46. Temperature compensation of monitoring circuit for silicon MEMS gyroscope

Author

杨波 Yang Bo, 王寿荣 Wang Shou-rong, 曹慧亮 Cao Hui-liang, 李宏生 Li Hong-sheng, and 黄丽斌 Huang Li-bin

Subjects
Engineering, Silicon, chemistry, business.industry, Vibrating structure gyroscope, Electronic engineering, chemistry.chemical_element, business, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, Compensation (engineering)
Published
2013

48. Two new prenylflavonoids from Morus alba

Author

Gao, Li, primary, Li, Yuan-Dong, additional, Zhu, Bao-Kun, additional, Li, Zhi-Yu, additional, Huang, Li-Bin, additional, Li, Xian-Yi, additional, Wang, Fei, additional, Ren, Fu-Cai, additional, and Liao, Tou-Gen, additional

Published
2017
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50. Multicenter randomized trial of arsenic trioxide and Realgar‐Indigo naturalis formula in pediatric patients with acute promyelocytic leukemia: Interim results of the SCCLG‐APL clinical study.

Author

Yang, Ming‐Hua, Wan, Wu‐Qing, Luo, Jie‐Si, Zheng, Min‐Cui, Huang, Ke, Yang, Li‐Hua, Mai, Hui‐Rong, Li, Jian, Chen, Hui‐Qin, Sun, Xiao‐Fei, Liu, Ri‐Yang, Chen, Guo‐Hua, Feng, Xiaoqin, Ke, Zhi‐Yong, Li, Bin, Tang, Yan‐Lai, Huang, Li‐Bin, and Luo, Xue‐Qun

Published
2018
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