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174 results on '"Huang, Keqing"'

2. Fluorinated polymer additives in Spiro-OMeTAD to improve the efficiency and stability of perovskite solar cells

Author

Tabi, Grace Dansoa, Nguyen, Dang-Thuan, Liang, Wensheng, Ji, Wenzhong, Lu, Teng, Trần-Phú, Thành, Lem, Olivier Lee Cheong, Mayon, Azul Osorio, Huang, Keqing, Chang, Li-Chun, Zhan, Hualin, Ahmad, Viqar, Mahmud, Arafat, Hou, Yihui, Wang, Wei, Bui, Anh Dinh, Nguyen, Hieu, Liu, Yun, Shen, Heping, Catchpole, Kylie R., Weber, Klaus J., White, Thomas P., Walter, Daniel, and Duong, The

Published
2024
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6. Universal Strategy with Structural and Chemical Crosslinking Interface for Efficient and Stable Perovskite Solar Cells

Author

Huang, Keqing, primary, Chang, Lichun, additional, Hou, Yihui, additional, Ji, Wenzhong, additional, Trần‐Phú, Thành, additional, Bui, Anh Dinh, additional, Mayon, Azul Osorio, additional, Wang, Wei, additional, Lem, Olivier Lee Cheong, additional, Nguyen, Dang‐Thuan, additional, Tabi, Grace Dansoa, additional, Duan, Leiping, additional, Liu, Yun, additional, Shen, Heping, additional, Yang, Junliang, additional, White, Thomas P., additional, Catchpole, Kylie R., additional, Weber, Klaus J., additional, and Duong, The, additional

Published
2024
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8. Void Formation and Radiation‐Induced Ion Migration in Perovskite Solar Cells under 10 MeV Proton Radiation.

Author

Nguyen, Dang‐Thuan, Bui, Anh Dinh, Huang, Keqing, Leung, Tik Lun, Chang, Li‐Chun, Nguyen, Khoa, Tabi, Grace Dansoa, Trần‐Phú, Thành, Nguyen, Hieu, Ho‐Baillie, Anita, Kluth, Patrick, Weber, Klaus, White, Thomas, and Duong, The

Subjects
SOLAR cells, ION migration & velocity, PEROVSKITE, PROTONS, RADIATION, PHOTOVOLTAIC power systems
Abstract

Perovskite solar cell (PSC) technology is a promising candidate for space applications because of its high power‐to‐weight ratio, low‐cost fabrication process, and good tolerance to high‐energy particle radiation. In this work, perovskite films and resultant high‐efficiency PSCs are assessed under 10 MeV proton radiation at fluences in the range 1e12–1e14 p cm−2, which are equivalent to 1 to 100 years in geostationary orbit (GEO) without any shielding or cover. For the first time, void formation and material ablation are detected on perovskite films, indicating structural damage of the materials under the proton radiation. Furthermore, ions inside the devices especially Au and Pb ions are displaced to underlying layers under the proton bombardment. These lead to the degradation of PSCs to ≈89% of the initial performance (from 24.1% to 21.4%) at the highest dose. The experimental results are supported by previous simulation works with a good fit in all optoelectronic parameters. This study provides insights into the degradation mechanism of PSCs under proton radiation and paves the way for the utilization of PSCs in space applications. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Constructing Additives Synergy Strategy to Doctor‐Blade Efficient CH3NH3PbI3 Perovskite Solar Cells under a Wide Range of Humidity from 45% to 82%

Author

Li, Hengyue, primary, Feng, Xiangxiang, additional, Huang, Keqing, additional, Lu, Siyuan, additional, Wang, Xinyue, additional, Feng, Erming, additional, Chang, Jianhui, additional, Long, Caoyu, additional, Gao, Yuanji, additional, Chen, Zhihui, additional, Yi, Chenyi, additional, He, Jun, additional, and Yang, Junliang, additional

Published
2023
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19. Bulk Incorporation with 4‐Methylphenethylammonium Chloride for Efficient and Stable Methylammonium‐Free Perovskite and Perovskite‐Silicon Tandem Solar Cells

Author

Duong, The, primary, Nguyen, Thuan, additional, Huang, Keqing, additional, Pham, Huyen, additional, Adhikari, Sunita Gautam, additional, Khan, Motiur Rahman, additional, Duan, Leiping, additional, Liang, Wensheng, additional, Fong, Kean Chern, additional, Shen, Heping, additional, Bui, Anh Dinh, additional, Mayon, Azul Osorio, additional, Truong, Thien, additional, Tabi, Grace, additional, Ahmad, Viqar, additional, Surve, Sachin, additional, Tong, Jingnan, additional, Kho, Teng, additional, Tran‐Phu, Thanh, additional, Lu, Teng, additional, Zheng, Jianghui, additional, Paetzold, Ulrich W., additional, Lemmer, Uli, additional, Baillie, Anita Ho, additional, Liu, Yun, additional, Andersson, Gunther, additional, White, Thomas, additional, Weber, Klaus, additional, and Catchpole, Kylie, additional

Published
2023
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26. A Two-Layer Location Choice Model Reveals What's New in the "New Retail".

Author

Xu, Liyan, Li, Fu, Huang, Keqing, and Ning, Jing

Subjects
ELECTRONIC commerce, COMPETITIVE advantage in business, STORE location, COFFEEHOUSES, INTERNET, ARTIFICIAL intelligence
Abstract

Copyright of Annals of the American Association of Geographers is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023
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30. Modulation of intestinal microbiota by glycyrrhizic acid prevents high-fat diet-enhanced pre-metastatic niche formation and metastasis

Author

Honglei Chen, Chenlong Wang, Yanzhuo Liu, Xiaoxiao Liu, Jing Yang, Miao Qiu, Yuqing Yang, Jing Zhang, Huang Keqing, Yu Xiong, and Honglin Tang

Subjects
0301 basic medicine, Colon, Immunology, Anti-Inflammatory Agents, Melanoma, Experimental, Macrophage polarization, CCL2, Gut flora, Diet, High-Fat, HMGB1, Metastasis, Immunomodulation, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Tumor Microenvironment, medicine, Animals, Humans, Immunology and Allergy, Calgranulin A, Neoplasm Metastasis, biology, Chemistry, Macrophages, digestive, oral, and skin physiology, Deoxycholic acid, NF-kappa B, Cell migration, Glycyrrhizic Acid, biology.organism_classification, medicine.disease, Gastrointestinal Microbiome, Phenotype, 030104 developmental biology, Cancer research, biology.protein, Cytokines, Dysbiosis, 030215 immunology
Abstract

High-fat diet (HFD) promotes lung pre-metastatic niche formation and metastasis. Thus, there is an urgent need to identify the underlying mechanisms and develop strategies to overcome them. Here we demonstrate that glycyrrhizic acid (GA) prevents HFD-enhanced pre-metastatic niche formation and metastasis through gut microbiota. GA reduced HFD-enhanced myeloid-derived suppressor cell recruitment, pro-metastatic protein S100A8/A9 expression and metastasis burden of 4T1 breast cancer and B16F10 melanoma, accompanied by gut microbiota alteration and colonic macrophage polarization far away the M1-like phenotype. These parameters were greatly decreased by treatment with antibiotics, recolonization of Desulfovibrio vulgaris and Clostridium sordellii, and administration of lipopolysaccharide or deoxycholic acid. Macrophage depletion attenuated HFD-enhanced pre-metastatic niche formation and metastasis, but failed to further affect the effects of GA. Mechanistically, counteraction of HFD-enhanced gut microbiota dysbiosis by GA inhibited Gr-1+ myeloid cell migration and S100A8/A9 expression through decreasing the proportion of M1-like macrophages and their production of CCL2 and TNF-α in the colons via LPS/HMGB1/NF-κB signaling inactivation. Together, targeting the gut microbiota by GA to modulate colonic macrophages could be a novel strategy for the prevention of HFD-enhanced pre-metastatic niche formation and metastasis.

Published
2019

31. Creating a Dual‐Functional 2D Perovskite Layer at the Interface to Enhance the Performance of Flexible Perovskite Solar Cells

Author

Long, Caoyu, primary, Huang, Keqing, additional, Chang, Jianhui, additional, Zuo, Chuantian, additional, Gao, Yuanji, additional, Luo, Xin, additional, Liu, Biao, additional, Xie, Haipeng, additional, Chen, Zhihui, additional, He, Jun, additional, Huang, Han, additional, Gao, Yongli, additional, Ding, Liming, additional, and Yang, Junliang, additional

Published
2021
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34. CYP4X1 Inhibition by Flavonoid CH625 Normalizes Glioma Vasculature through Reprogramming TAMs via CB2 and EGFR-STAT3 Axis

Author

Jing Yang, Chenlong Wang, Yuqing Yang, Miao Qiu, Ying Li, Honglei Chen, Huang Keqing, Yanzhuo Liu, and Xiaoxiao Liu

Subjects
STAT3 Transcription Factor, 0301 basic medicine, Angiogenesis, T-Lymphocytes, T cell, Down-Regulation, Peripheral blood mononuclear cell, Receptor, Cannabinoid, CB2, Neovascularization, 03 medical and health sciences, Cytochrome P-450 Enzyme System, Downregulation and upregulation, Cell Movement, Transforming Growth Factor beta, Cell Line, Tumor, Glioma, medicine, Cytochrome P-450 Enzyme Inhibitors, Humans, STAT3, Flavonoids, Pharmacology, Neovascularization, Pathologic, biology, Chemistry, Macrophages, medicine.disease, ErbB Receptors, 030104 developmental biology, medicine.anatomical_structure, Cancer research, biology.protein, Molecular Medicine, Pericyte, medicine.symptom
Abstract

Tumor-associated macrophages (TAMs) are pivotal effector cells in angiogenesis. Here, we tested whether CYP4X1 inhibition in TAMs by flavonoid CH625 prolongs survival and normalizes glioma vasculature. CH625 was selected against the CYP4X1 3D model by virtual screening and showed inhibitory activity on the CYP4X1 catalytic production of 14,15-EET-EA in the M2-polarized human peripheral blood mononuclear cells (IC50 = 16.5 μM). CH625 improved survival and reduced tumor burden in the C6 and GL261 glioma intracranial and subcutaneous model. In addition, CH625 normalized vasculature (evidenced by a decrease in microvessel density and HIF-1α expression and an increase in tumor perfusion, pericyte coverage, and efficacy of temozolomide therapy) accompanied with the decreased secretion of 14,15-EET-EA, VEGF, and TGF-β in the TAMs. Furthermore, CH625 attenuated vascular abnormalization and immunosuppression induced by coimplantation of GL261 cells with CYP4X1high macrophages. In vitro TAM polarization away from the M2 phenotype by CH625 inhibited proliferation and migration of endothelial cells, enhanced pericyte migration and T cell proliferation, and decreased VEGF and TGF-β production accompanied with the downregulation of CB2 and EGFR-dependent downstream STAT3 expression. These effects were reversed by overexpression of CYP4X1 and STAT3 or exogenous addition of 14,15-EET-EA, VEGF, TGF-β, EGF, and CB2 inhibitor AM630. These results suggest that CYP4X1 inhibition in TAMs by CH625 prolongs survival and normalizes tumor vasculature in glioma via CB2 and EGFR-STAT3 axis and may serve as a novel therapeutic strategy for human glioma.

Published
2018

35. Progress on growth of metal halide perovskites by vapor-phase synthesis and their applications.

Author

Xiang, Yang, Mo, Xindi, Li, Xing, Huang, Keqing, He, Pei, Dai, Guozhang, and Yang, Junliang

Subjects
METAL halides, OPTOELECTRONIC devices, LIGHT emitting diodes, SOLAR cells, THIN films
Abstract

Metal halide perovskites (MHPs) show excellent optoelectronic properties and exhibit great potential applications in optoelectronic devices, such as solar cells (SCs), photodetectors, light-emitting diodes (LEDs), lasers, and so on. Vapor-phase synthesis provides an important way to grow large-scale, high-quality MHP thin films and micro-/nanostructures, exhibiting wide applications in constructing all kinds of optoelectronic devices. In this review, we systematically summarize the growth of perovskite thin film and the nano-/microstructure by vapor-phase synthesis. The detailed classification of vapor-phase synthesis is first introduced, and the effects of the substrates on the growth process are discussed subsequently. Then, the applications of perovskite thin films and micro-/nanostructures grown by vapor-phase synthesis in SCs, photodetectors, LEDs, lasers, and so forth, are discussed in detail. Finally, the conclusions and outlook are presented. [ABSTRACT FROM AUTHOR]

Published
2022
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36. Efficient organic solar cells with the active layer fabricated from glovebox to ambient condition

Author

Li, Hengyue, primary, Huang, Keqing, additional, Dong, Yanan, additional, Guo, Xiaotong, additional, Yang, Yu, additional, Luo, Qun, additional, Ma, Chang-Qi, additional, Li, Dongfan, additional, Lu, Guanghao, additional, Xiong, Jian, additional, Zhang, Jian, additional, Yang, Yingguo, additional, Gao, Xingyu, additional, and Yang, Junliang, additional

Published
2020
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37. γ-ray Radiation on Flexible Perovskite Solar Cells

Author

Huang, Keqing, primary, Yang, Kaixin, additional, Li, Hengyue, additional, Zheng, Shuaizhi, additional, Wang, Jinbin, additional, Guo, Hongxia, additional, Peng, Yongyi, additional, Zhong, Xiangli, additional, and Yang, Junliang, additional

Published
2020
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45. Revealing the microstructure evolution of inorganic CsPbI2Br perovskite via synchrotron radiation grazing incidence X‐ray diffraction.

Author

Dong, Yanan, Huang, Keqing, Chang, Jianhui, Zhang, Jian, Yang, Yingguo, and Yang, Junliang

Abstract

Perovskite devices have been developed rapidly over the past decade and all‐inorganic perovskite devices have attracted wide interest due to their outstanding stability. The crystallization process and microstructures of inorganic perovskite play important roles on the device performance. Herein, synchrotron radiation grazing incidence X‐ray diffraction (GIXRD) was utilized to investigate the microstructure evolution of CsPbI2Br all‐inorganic perovskite film during post annealing, as well as its influence on the performance of CsPbI2Br perovskite solar cells (PSCs). It was found that high‐temperature (240°C) flash annealing accelerated the precursor solution to rapidly crystallize within a few seconds and reduced the generation of non‐perovskite phase. The centroid and full‐width at half‐maximum (FWHM) of perovskite diffraction peaks, corresponding to lattice constant and crystallite size of perovskite, respectively, changed gradually with the flash annealing time. The flash annealing time was optimized to be 10 seconds, leading to the suitable microstructure and crystallite size, as well as the best photovoltaic performance of PSCs. These results indicate that the microstructure evolution of all‐inorganic perovskite film during the post flash annealing plays a key role in the device performance. [ABSTRACT FROM AUTHOR]

Published
2021
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46. Multi-walled carbon nanotubes exacerbate doxorubicin-induced cardiotoxicity by altering gut microbiota and pulmonary and colonic macrophage phenotype in mice

Author

Yanzhuo Liu, Xuewei Chen, Xiaoxiao Liu, Honglei Chen, Chenlong Wang, Wen Liu, Huang Keqing, Jing Yang, and Xuehan Chen

Subjects
Male, 0301 basic medicine, Heart Diseases, Colon, Interleukin-1beta, Macrophage polarization, Apoptosis, Gut flora, Pharmacology, Toxicology, Feces, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Macrophage, Myocytes, Cardiac, Doxorubicin, Lung, Cells, Cultured, Chemokine CCL2, Cardiotoxicity, Antibiotics, Antineoplastic, biology, Nanotubes, Carbon, Tumor Necrosis Factor-alpha, Chemistry, Macrophages, biology.organism_classification, medicine.disease, Anti-Bacterial Agents, Gastrointestinal Microbiome, Mice, Inbred C57BL, Phenotype, 030104 developmental biology, Mechanism of action, Dysbiosis, medicine.symptom, 030217 neurology & neurosurgery, medicine.drug
Abstract

Epidemiologic studies show that the levels of air pollutants and particulate matter are positively associated with the morbidity and mortality of cardiovascular diseases. Here we demonstrate that the intratracheal instillation of multi-walled carbon nanotubes (MWCNTs), a standard fine particle, exacerbate doxorubicin (DOX)-induced cardiotoxicity in mice through altering gut microbiota and pulmonary and colonic macrophage phenotype. MWCNTs (25 μg/kg per day, 5 days a week for 3 weeks) promoted cardiotoxicity and apoptosis in the DOX (2 mg/kg, twice a week for 5 weeks)-treated C57BL/6 mice. MWCNTs exaggerated DOX-induced gut microbiota dysbiosis characterized by the increased abundances of Helicobacteraceae and Coriobacteriaceae. In addition, MWCNTs promoted DOX-induced M1-like polarization of colonic macrophages with an increase in TNF-α, IL-1β and CC chemokine ligand 2 in peripheral blood. Importantly, treatment with the antibiotics attenuated MWCNTs plus DOX-induced apoptosis of cardiomyocytes and M1-like polarization of colonic macrophages. The fecal microbiota transplantation demonstrated that MWCNTs exaggerated DOX-induced cardiotoxicity with M1-like polarization of colonic macrophages. The conditioned medium from MWCNTs-treated pulmonary macrophages promoted DOX-induced gut microbiota dysbiosis and colonic macrophage polarization. Furthermore, the co-culture of macrophages and fecal bacteria promoted M1-like macrophage polarization and their production of TNF-α and IL-1β, and thereby exacerbated the effects of MWCNTs. Moreover, IL-1β and TNF-α blockade, either alone or in combination attenuated MWCNTs-exacerbated cardiotoxicity. In summary, MWCNTs exacerbate DOX-induced cardiotoxicity in mice through gut microbiota and pulmonary and colonic macrophage interaction. Our findings identify a novel mechanism of action of inhaled particle-driven cardiotoxicity.

Published
2020

49. Radiation tolerance of perovskite solar cells under gamma ray

Author

Yang, Kaixin, primary, Huang, Keqing, additional, Li, Xiaolei, additional, Zheng, Shuaizhi, additional, Hou, Pengfei, additional, Wang, Jinbin, additional, Guo, Hongxia, additional, Song, Hongjia, additional, Li, Bo, additional, Li, Hengyue, additional, Liu, Biao, additional, Zhong, Xiangli, additional, and Yang, Junliang, additional

Published
2019
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